Yang Zhang's Research Group

We are interested in:
I-TASSER model vs crystal structure of T0604_1, a CASP9 FM target

    Determining structure and function of protein molecules is a cornerstone of modern biology and medicine. The main focus of our lab is to develop bioinformatics algorithms to predict 3-dimensional structure of protein molecules from amino acid sequence and deduce the biological functions based on the sequence-to-structure-to-function paradigm. We are also working on protein engineering and design, as well as modeling ligand-protein and protein-protein interactions. We are especially interested in the structure of G protein-coupled receptors (GPCR) and the interactions with associated ligands with the purpose of developing new drugs to regulate these interactions ( >> read more ... ).

The Zhang Lab news:

Research Highlights:

 


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