Determining structure and function of protein molecules is a cornerstone
of modern biology and medicine. The main focus of our lab is
to develop bioinformatics algorithms to predict 3-dimensional structures
of protein molecules from amino acid sequences
and deduce the biological functions based on the
sequence-to-structure-to-function paradigm.
We are also working on the modeling of ligand-protein and protein-protein interactions.
We are especially interested in the structures of G protein-coupled receptors
(GPCR) and the interactions with the associated ligands with the purpose of
developing new drugs to regulate these interactions
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