GLASS (GPCR-Ligand Association) database is a manually curated repository for experimentally-validated GPCR-ligand interactions. Along with relevant GPCR and chemical information, GPCR-ligand association data are extracted and integrated into GLASS from literature and public databases. (>>more about the GLASS database)
The current database was updated on February 16, 2016, which contains:
February 14, 2016:
Happy Valentine's Day! The browse ligand and browse family features have been fixed. Thank you to Hongjiu Zhang for assistance.
August 5, 2016: Added 2D molecule structures to GPCR search results. Thank you to Dr. Andrew Horti for this useful suggestion. This change should hopefully facilitate the browsing of molecules.
June 24, 2016: Fixed bug where DrugBank entries were not showing up.
March 1, 2015: Redesigned the database schemas.
February 17, 2015: Migrated the website to the new framework.
August 12, 2014: Added searches for GPCR by family and for ligands by chemical structure.
June 30, 2014: Added batch TSV and SDF download.
June 28, 2014: Added synonyms for GPCRs and ligands, as well as Lipinski's rule of five check.
June 24, 2014: Set up the database website.
W Chan, H Zhang, J Yang, J Brender, J Hur, A Ozgur, Y Zhang. GLASS: a comprehensive database for experimentally-validated GPCR-ligand associations. Bioinformatics, 31: 3035-3042 (2015). [PDF] [Support Information] [Database]
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