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Name | Lysophosphatidic acid receptor 3 |
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Species | Rattus norvegicus (Rat) |
Gene | Lpar3 |
Synonym | Edg7 endothelial differentiation gene 7, lysophosphatidic acid G-protein-coupled receptor 7 LPA receptor 3 LPA-3 LPA3 receptor [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 354 |
Amino acid sequence | MNECHYDKRMDFFYNRSNTDTADEWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVITNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWLLRQGLLDTSLTASLANLLVIAVERHMSIMRMRIHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLIFWTVSNLLAFFIMVVVYVRIYMYVKRKTNVLSPHTSGSISRRRAPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCKQCNVQHVKRWFLLLALLNSVMNPIIYSYKDEDMYNTMRKMICCAPHDSNAERHPSRIPSTIHSRSDTGSQYLEDSISQGQVCNKSSS |
UniProt | Q8K5E0 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4424 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL199400 |
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Molecular formula | C21H40O5PS- |
IUPAC name | [(2R,4R)-2-[(E)-heptadec-9-enyl]-1,3-dioxolan-4-yl]methoxy-hydroxy-oxido-sulfanylidene-lambda5-phosphane |
Molecular weight | 435.58 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 1 |
XlogP | 7.7 |
Synonyms | potassium O-((2R,4R)-2-(heptadec-9-enyl)-1,3-dioxolan-4-yl)methyl O-hydrogenphosphorothioate BDBM50177335 |
Inchi Key | GPCDCYBCUTWZFV-OBDVNYBASA-M |
Inchi ID | InChI=1S/C21H41O5PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-24-18-20(26-21)19-25-27(22,23)28/h8-9,20-21H,2-7,10-19H2,1H3,(H2,22,23,28)/p-1/b9-8+/t20-,21-/m1/s1 |
PubChem CID | 91936391 |
ChEMBL | N/A |
IUPHAR | N/A |
BindingDB | 50177335 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 194.0 nM | PMID16290140 | BindingDB |
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