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Name | Putative P2Y purinoceptor 10 |
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Species | Homo sapiens (Human) |
Gene | P2RY10 |
Synonym | P2Y-like receptor P2RY10 purinergic receptor P2Y purinergic receptor P2Y, G-protein coupled 10 purinergic receptor P2Y10 [ Show all ] |
Disease | N/A |
Length | 339 |
Amino acid sequence | MANLDKYTETFKMGSNSTSTAEIYCNVTNVKFQYSLYATTYILIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMYASICFLTCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILRSTDLNNNKSCFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTISLRQPPMAFQGISERQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETIISSCPVVRIALYFHPFCLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSKESGSSMIG |
UniProt | O00398 |
Protein Data Bank | N/A |
GPCR-HGmod model | O00398 |
3D structure model | This predicted structure model is from GPCR-EXP O00398. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3562166 |
IUPHAR | 165 |
DrugBank | N/A |
Name | Sphingosine 1-phosphate |
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Molecular formula | C18H38NO5P |
IUPAC name | [(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enyl] dihydrogen phosphate |
Molecular weight | 379.478 |
Hydrogen bond acceptor | 6 |
Hydrogen bond donor | 4 |
XlogP | 1.9 |
Synonyms | ZINC8860500 (2-amino-3-hydroxy-octadec-4-enoxy)phosphonic acid (E)-D-erythro-2-amino-1-(dihydrogenphosphate)-4-octadecene-1,3-diol C18H38NO5P D07UGA [ Show all ] |
Inchi Key | DUYSYHSSBDVJSM-KRWOKUGFSA-N |
Inchi ID | InChI=1S/C18H38NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h14-15,17-18,20H,2-13,16,19H2,1H3,(H2,21,22,23)/b15-14+/t17-,18+/m0/s1 |
PubChem CID | 5283560 |
ChEMBL | CHEMBL225155 |
IUPHAR | 911 |
BindingDB | 50158348 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 50.1187 nM | PMID18466763 | IUPHAR |
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