You can:
| Name | Alpha-1A adrenergic receptor |
|---|---|
| Species | Oryctolagus cuniculus (Rabbit) |
| Gene | ADRA1A |
| Synonym | Alpha-1A adrenoceptor Alpha-1A adrenoreceptor Alpha-1C adrenergic receptor |
| Disease | N/A for non-human GPCRs |
| Length | 466 |
| Amino acid sequence | MVFLSGNASDSSNCTHPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIISLCVISIDRYIGVSYPLRYPTIVTQRRGLRALLCVWAFSLVISVGPLFGWRQPAPDDETICQINEEPGYVLFSALGSFYVPLTIILAMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGVASAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPPETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLKIQCLRRKQSSKHALGYTLHAPSQALEGQHKDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPRGSARITVPKDQSACTTARVRSKSFLQVCCCVGPSTPNPGENHQVPTIKIHTISLSENGEEV |
| UniProt | O02824 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3637 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 2112 |  CHEMBL91326 | C24H34N4O2 | 410.562 | 5 / 1 | 4.2 | Yes |
| 3641 |  LASSBio-683 | C20H25ClN2O3 | 376.881 | 5 / 1 | N/A | N/A |
| 8207 |  BW-723C86 | C16H18N2OS | 286.393 | 3 / 2 | 3.0 | Yes |
| 12756 |  CHEMBL327168 | C24H30N6O2 | 434.544 | 7 / 1 | 3.2 | Yes |
| 13575 |  CHEMBL91989 | C27H32F3N5O2 | 515.581 | 9 / 1 | 5.3 | No |
| 16276 |  CHEMBL88181 | C23H31N3O2S | 413.58 | 5 / 0 | 3.9 | Yes |
| 17890 |  Bmy-7378 | C22H31N3O3 | 385.508 | 5 / 0 | 2.8 | Yes |
| 18824 |  LASSBio-724 | C19H25ClN2 | 316.873 | 2 / 1 | N/A | N/A |
| 26545 |  Rauwolscine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26616 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 28650 |  CHEMBL313775 | C25H32F3N7O2 | 519.573 | 10 / 2 | 4.1 | No |
| 30251 |  CHEMBL111372 | C14H17N3O3S | 307.368 | 5 / 3 | 1.4 | Yes |
| 32031 |  CHEMBL88160 | C26H34F3N7O2 | 533.6 | 10 / 1 | 4.3 | No |
| 36164 |  CHEMBL433348 | C23H30N4O2 | 394.519 | 6 / 1 | 3.8 | Yes |
| 39215 |  CHEMBL92901 | C22H31N5O2 | 397.523 | 6 / 2 | 3.3 | Yes |
| 46428 |  LASSBio-773 | C21H27ClN2O3 | 390.908 | 5 / 1 | N/A | N/A |
| 49599 |  CHEMBL330579 | C23H30F3N5O2 | 465.521 | 9 / 1 | 4.3 | Yes |
| 53647 |  CHEMBL327351 | C22H31N5O3 | 413.522 | 7 / 2 | 2.8 | Yes |
| 54776 |  CHEMBL2153423 | C20H25ClN2O3 | 376.881 | 5 / 1 | N/A | N/A |
| 63154 |  phenylpropanolamine | C9H13NO | 151.209 | 2 / 2 | 0.8 | Yes |
| 66963 |  TAMSULOSIN | C20H28N2O5S | 408.513 | 7 / 2 | 2.7 | Yes |
| 70957 |  CHEMBL2261355 | C15H19N3O2S | 305.396 | 4 / 2 | 2.1 | Yes |
| 70961 |  CHEMBL111496 | C15H19N3O2S | 305.396 | 4 / 2 | 2.1 | Yes |
| 73325 |  CHEMBL314114 | C22H28F3N5O | 435.495 | 8 / 1 | 4.1 | Yes |
| 84497 |  CHEMBL327231 | C27H33FN8O2 | 520.613 | 9 / 1 | 3.4 | No |
| 87185 |  SCHEMBL7097480 | C14H17N3O2S | 291.369 | 4 / 2 | 1.7 | Yes |
| 87191 |  CHEMBL111554 | C14H17N3O2S | 291.369 | 4 / 2 | 1.7 | Yes |
| 88072 |  CHEMBL111463 | C15H19N3O2S | 305.396 | 4 / 1 | 1.9 | Yes |
| 92852 |  CHEMBL90878 | C27H31ClF3N5O2 | 550.023 | 9 / 1 | 5.9 | No |
| 94252 |  CHEMBL330060 | C23H32N4O2 | 396.535 | 5 / 1 | 3.9 | Yes |
| 99300 |  CHEMBL89397 | C27H31FN6O2 | 490.583 | 8 / 1 | 4.0 | Yes |
| 100357 |  CHEMBL88633 | C21H30N6O2 | 398.511 | 7 / 1 | 2.5 | Yes |
| 105686 |  CHEMBL90746 | C27H33N5O | 443.595 | 5 / 1 | 4.8 | Yes |
| 106597 |  CHEMBL314880 | C26H34N6O | 446.599 | 5 / 1 | 3.9 | Yes |
| 109253 |  CHEMBL91951 | C24H33N5O | 407.562 | 5 / 1 | 4.1 | Yes |
| 115739 |  5-Methylurapidil | C21H31N5O3 | 401.511 | 6 / 1 | 1.9 | Yes |
| 120824 |  IDAZOXAN | C11H12N2O2 | 204.229 | 3 / 1 | 0.7 | Yes |
| 127331 |  LASSBio-675 | C21H27ClN2O2 | 374.909 | 4 / 1 | N/A | N/A |
| 127713 |  Ethanesulfonamide, N-[3-(1H-imidazol-4-ylmethyl)-2-methylphenyl]- | C13H17N3O2S | 279.358 | 4 / 2 | 1.7 | Yes |
| 131372 |  prazosin | C19H21N5O4 | 383.408 | 8 / 1 | 2.0 | Yes |
| 133225 |  CHEMBL329601 | C22H31N5OS | 413.584 | 6 / 1 | 3.7 | Yes |
| 134310 |  CHEMBL329773 | C23H30ClFN7O2+ | 490.988 | 7 / 2 | 4.0 | Yes |
| 138899 |  CHEMBL91480 | C23H33N5O3 | 427.549 | 7 / 1 | 3.1 | Yes |
| 141171 |  CHEMBL322492 | C15H19N3O2S | 305.396 | 4 / 2 | 2.3 | Yes |
| 143488 |  CHEMBL111682 | C12H15N3O2S | 265.331 | 4 / 2 | 1.3 | Yes |
| 148855 |  CHEMBL91605 | C25H34FN7O2 | 483.592 | 8 / 1 | 3.3 | Yes |
| 150344 |  CHEMBL89222 | C21H30N6O | 382.512 | 6 / 1 | 2.5 | Yes |
| 447695 |  SCHEMBL7098572 | C14H15N3O2S | 289.353 | 4 / 2 | 1.3 | Yes |
| 168737 |  CHEMBL89822 | C29H40F3N7O2 | 575.681 | 10 / 1 | 5.6 | No |
| 174093 |  CHEMBL323440 | C15H19N3O2S | 305.396 | 4 / 2 | 2.1 | Yes |
| 178396 |  CHEMBL315496 | C27H33FN6O3 | 508.598 | 8 / 2 | 3.1 | No |
| 179542 |  CHEMBL327872 | C23H30N6O2 | 422.533 | 7 / 1 | 2.9 | Yes |
| 180194 |  CHEMBL88664 | C21H29N5O2 | 383.496 | 6 / 2 | 2.8 | Yes |
| 187159 |  CHEMBL91547 | C23H31FN7O2+ | 456.546 | 7 / 2 | 3.4 | Yes |
| 188280 |  CHEMBL90869 | C23H29F3N4O3 | 466.505 | 9 / 1 | 3.6 | Yes |
| 189543 |  CHEMBL109755 | C14H19N3O2S | 293.385 | 4 / 2 | 0.8 | Yes |
| 190047 |  LASSBio-730 | C20H27ClN2 | 330.9 | 2 / 1 | N/A | N/A |
| 194466 |  A 61603 HYDROBROMIDE | C14H20BrN3O3S | 390.296 | 5 / 4 | N/A | N/A |
| 199745 |  CHEMBL111584 | C15H19N3O2S | 305.396 | 4 / 1 | 1.7 | Yes |
| 209328 |  CHEMBL88856 | C22H28N6O | 392.507 | 6 / 1 | 2.9 | Yes |
| 209727 |  UNII-2L5SGH4CVS | C22H31N5O2 | 397.523 | 6 / 1 | 3.1 | Yes |
| 212212 |  AC1NKXXY | C17H19N3O | 281.359 | 2 / 2 | 3.3 | Yes |
| 214314 |  CHEMBL442394 | C15H19N3O3S | 321.395 | 5 / 2 | 1.7 | Yes |
| 218775 |  CHEMBL111537 | C16H21N3O2S | 319.423 | 4 / 2 | 2.5 | Yes |
| 233959 |  CHEMBL111151 | C13H15N3O3S | 293.341 | 5 / 2 | 0.9 | Yes |
| 238056 |  LASSBio-728 | C18H23ClN2O | 318.845 | 3 / 1 | N/A | N/A |
| 245836 |  CHEMBL420620 | C22H30FN5O2 | 415.513 | 7 / 1 | 3.2 | Yes |
| 247709 |  A61603 | C14H19N3O3S | 309.384 | 5 / 3 | 0.4 | Yes |
| 248365 |  LASSBio-670 | C20H25ClN2O3 | 376.881 | 5 / 1 | N/A | N/A |
| 254465 |  CHEMBL91278 | C25H35N5O2 | 437.588 | 6 / 1 | 3.9 | Yes |
| 258378 |  CHEMBL93054 | C21H29N5O2 | 383.496 | 6 / 2 | 3.0 | Yes |
| 260874 |  CHEMBL111771 | C14H17N3O2S | 291.369 | 4 / 2 | 1.5 | Yes |
| 262642 |  CHEMBL88435 | C22H31N5O | 381.524 | 5 / 1 | 3.5 | Yes |
| 283153 |  CHEMBL93736 | C22H31N5O2 | 397.523 | 6 / 1 | 2.8 | Yes |
| 284976 |  CHEMBL91338 | C23H31N3O3 | 397.519 | 5 / 0 | 3.3 | Yes |
| 288597 |  CHEMBL90287 | C21H29N5O | 367.497 | 5 / 1 | 3.2 | Yes |
| 292545 |  CHEMBL91785 | C23H33N5O2 | 411.55 | 6 / 1 | 3.5 | Yes |
| 292639 |  CHEMBL89030 | C24H34N4O2 | 410.562 | 5 / 1 | 4.2 | Yes |
| 300023 |  CHEMBL108804 | C14H17N3O3S | 307.368 | 5 / 3 | 1.4 | Yes |
| 301537 |  ABT-866 | C12H15N3O2S | 265.331 | 4 / 2 | 1.4 | Yes |
| 304112 |  benalfocin | C11H14ClN | 195.69 | 1 / 0 | 2.9 | Yes |
| 306156 |  CHEMBL91400 | C24H35N5O | 409.578 | 5 / 1 | 4.5 | Yes |
| 308669 |  CHEMBL327232 | C22H31N5O3 | 413.522 | 7 / 2 | 2.8 | Yes |
| 317005 |  CHEMBL313157 | C23H33N5O2 | 411.55 | 6 / 1 | 3.5 | Yes |
| 318770 |  LASSBio-632 | C20H25ClN2O2 | 360.882 | 4 / 1 | N/A | N/A |
| 325760 |  CHEMBL109848 | C15H17N3O | 255.321 | 2 / 2 | 1.9 | Yes |
| 339226 |  LASSBio-629 | C19H23ClN2O3 | 362.854 | 5 / 1 | N/A | N/A |
| 346835 |  CHEMBL325897 | C16H19N3O2S | 317.407 | 4 / 2 | 2.3 | Yes |
| 348198 |  CHEMBL322082 | C14H16ClN3O2S | 325.811 | 4 / 2 | 2.3 | Yes |
| 349218 |  LASSBio-682 | C19H22Cl2N2O2 | 381.297 | 4 / 1 | N/A | N/A |
| 351663 |  terazosin | C19H25N5O4 | 387.44 | 8 / 1 | 1.4 | Yes |
| 353948 |  3600-87-1 | C10H15NO3 | 197.234 | 4 / 2 | 0.1 | Yes |
| 360515 |  LASSBio-719B | C17H21ClN2 | 288.819 | 2 / 1 | N/A | N/A |
| 362852 |  CHEMBL322042 | C14H16FN3O2S | 309.359 | 5 / 2 | 1.8 | Yes |
| 376199 |  LASSBio-771 | C18H23ClN2 | 302.846 | 2 / 1 | N/A | N/A |
| 377608 |  CHEMBL110751 | C15H14F3N3O | 309.292 | 5 / 2 | 3.0 | Yes |
| 383609 |  CHEMBL315785 | C25H34FN7O2 | 483.592 | 8 / 1 | 3.2 | Yes |
| 384620 |  CHEMBL88109 | C25H30N6O2 | 446.555 | 7 / 1 | 2.5 | Yes |
| 389303 |  CHEMBL328545 | C28H35N5O | 457.622 | 5 / 1 | 5.1 | No |
| 395355 |  RS-17053 | C24H29ClN2O2 | 412.958 | 3 / 2 | 5.5 | No |
zhanglab
zhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218