You can:
| Name | Thyrotropin-releasing hormone receptor |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Trhr |
| Synonym | Thyroliberin receptor TRH receptor TRH-R TRH-R1 TRH1 receptor |
| Disease | N/A for non-human GPCRs |
| Length | 393 |
| Amino acid sequence | MENDTVSEMNQTELQPQAAVALEYQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKESDRFSTELEDITVTDTYVSTTKVSFDDTCLASEN |
| UniProt | P21761 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2467 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 521703 |  CHEMBL3780191 | C19H26I2N6O4 | 656.264 | 5 / 3 | -0.3 | No |
| 521837 |  CHEMBL3780248 | C23H27ClN6O4 | 486.957 | 5 / 3 | 0.7 | Yes |
| 15591 |  CHEMBL607173 | C21H26N4O4 | 398.463 | 4 / 2 | 0.1 | Yes |
| 15592 |  BDBM50050529 | C21H26N4O4 | 398.463 | 4 / 2 | 0.1 | Yes |
| 521925 |  CHEMBL3781522 | C17H23ClN6O4 | 410.859 | 5 / 3 | -1.2 | Yes |
| 467704 |  CHEMBL3600445 | C23H23I2N7O3 | 699.292 | 6 / 2 | 1.5 | No |
| 470292 |  CHEMBL3601786 | C18H21I2N7O3 | 637.221 | 6 / 2 | 0.2 | No |
| 523777 |  CHEMBL3782037 | C18H25IN6O4 | 516.34 | 5 / 3 | -1.2 | No |
| 524462 |  CHEMBL3781773 | C23H27IN6O4 | 578.411 | 5 / 3 | 0.4 | No |
| 524535 |  CHEMBL3780836 | C16H20Cl2N6O4 | 431.274 | 5 / 4 | -0.5 | Yes |
| 524581 |  CHEMBL3780549 | C23H26I2N6O4 | 704.308 | 5 / 3 | 0.5 | No |
| 479319 |  CHEMBL3600448 | C19H26N8O3 | 414.47 | 7 / 4 | -0.1 | Yes |
| 525480 |  CHEMBL3779931 | C18H25BrN6O4 | 469.34 | 5 / 3 | -0.8 | Yes |
| 143758 |  Pyr3TRH | C17H23N5O4 | 361.402 | 5 / 3 | -2.1 | Yes |
| 481206 |  CHEMBL3601781 | C17H20BrN7O3 | 450.297 | 6 / 3 | 0.0 | Yes |
| 155806 |  CHEMBL180789 | C20H18ClN3O3 | 383.832 | 4 / 1 | 5.2 | No |
| 482357 |  CHEMBL3601782 | C16H19BrN8O3 | 451.285 | 7 / 4 | -0.2 | Yes |
| 483095 |  CHEMBL3601785 | C17H20BrN7O3 | 450.297 | 6 / 2 | -0.5 | Yes |
| 187122 |  CHEMBL2370383 | C19H30N4O4 | 378.473 | 4 / 3 | 0.5 | Yes |
| 527365 |  CHEMBL3781024 | C23H27BrN6O4 | 531.411 | 5 / 3 | 0.7 | No |
| 488302 |  CHEMBL3600444 | C24H25I2N7O3 | 713.319 | 6 / 2 | 1.9 | No |
| 527548 |  CHEMBL3780633 | C17H22I2N6O4 | 628.21 | 5 / 3 | -1.1 | No |
| 527755 |  CHEMBL3780802 | C18H24I2N6O4 | 642.237 | 5 / 3 | -0.8 | No |
| 491326 |  CHEMBL3600447 | C20H27N7O3 | 413.482 | 6 / 3 | 0.1 | Yes |
| 528430 |  CHEMBL3780645 | C17H23IN6O4 | 502.313 | 5 / 3 | -1.5 | No |
| 494591 |  CHEMBL3601784 | C16H17I2N7O3 | 609.167 | 6 / 3 | -0.1 | No |
| 260181 |  CHEMBL360939 | C20H19ClN2O | 338.835 | 2 / 1 | 5.0 | Yes |
| 277423 |  CHEMBL181006 | C20H19N3O3 | 349.39 | 4 / 1 | 4.5 | Yes |
| 278776 |  CHEMBL359845 | C20H19N3O3 | 349.39 | 4 / 1 | 4.5 | Yes |
| 291709 |  PK 11195 | C21H21ClN2O | 352.862 | 2 / 0 | 5.5 | No |
| 300717 |  CHEMBL180456 | C17H13ClN2O | 296.754 | 2 / 1 | 4.0 | Yes |
| 500331 |  CHEMBL3600452 | C16H18BrN7O3 | 436.27 | 6 / 3 | -0.4 | Yes |
| 310706 |  CHEMBL179883 | C18H15ClN2O | 310.781 | 2 / 1 | 4.4 | Yes |
| 312841 |  CHEMBL39363 | C17H24N6O4 | 376.417 | 5 / 3 | -2.2 | Yes |
| 501617 |  CHEMBL3600451 | C16H18ClN7O3 | 391.816 | 6 / 3 | -0.5 | Yes |
| 316216 |  CHEMBL180833 | C19H17ClN2O | 324.808 | 2 / 1 | 4.9 | Yes |
| 336991 |  CHEMBL107238 | C22H30N4O4 | 414.506 | 4 / 2 | 0.9 | Yes |
| 336992 |  CHEMBL319910 | C22H30N4O4 | 414.506 | 4 / 2 | 0.9 | Yes |
| 504981 |  CHEMBL3600446 | C19H25N7O3 | 399.455 | 6 / 3 | -0.3 | Yes |
| 356256 |  CHEMBL179860 | C21H21ClN2O | 352.862 | 2 / 0 | 5.4 | No |
| 360822 |  CHEMBL181118 | C20H19N3O3 | 349.39 | 4 / 1 | 4.5 | Yes |
| 531716 |  CHEMBL3780373 | C19H27BrN6O4 | 483.367 | 5 / 3 | -0.3 | Yes |
| 531724 |  CHEMBL3781873 | C16H20I2N6O4 | 614.183 | 5 / 4 | -1.1 | No |
| 510206 |  CHEMBL3600453 | C16H17Br2N7O3 | 515.166 | 6 / 3 | 0.6 | No |
| 396602 |  protirelin | C16H22N6O4 | 362.39 | 5 / 4 | -2.5 | Yes |
| 396605 |  Thyrotropin releasing hormone | C16H22N6O4 | 362.39 | 5 / 4 | -2.5 | Yes |
| 532908 |  CHEMBL3780746 | C17H23BrN6O4 | 455.313 | 5 / 3 | -1.1 | Yes |
| 403447 |  CHEMBL179861 | C20H19ClN2O | 338.835 | 2 / 1 | 5.3 | No |
| 512758 |  CHEMBL3601783 | C16H18Br2N8O3 | 530.181 | 7 / 4 | 0.8 | No |
| 514312 |  CHEMBL3600450 | C20H32N6O3 | 404.515 | 5 / 4 | 0.3 | Yes |
| 514865 |  CHEMBL3600449 | C20H32N6O3 | 404.515 | 5 / 4 | 0.4 | Yes |
| 426600 |  Pyroglutamyl-phenylalanyl-prolinamide | C19H24N4O4 | 372.425 | 4 / 3 | -0.6 | Yes |
| 517070 |  CHEMBL3600454 | C17H19Br2N7O3 | 529.193 | 6 / 3 | 1.0 | No |
zhanglab
zhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218