You can:
| Name | Type-1 angiotensin II receptor |
|---|---|
| Species | Bos taurus (Bovine) |
| Gene | AGTR1 |
| Synonym | Angiotensin II type-1 receptor AT1 |
| Disease | N/A for non-human GPCRs |
| Length | 359 |
| Amino acid sequence | MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFKIILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE |
| UniProt | P25104 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3374 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 660 |  CHEMBL47177 | C33H35N7O2 | 561.69 | 7 / 1 | 5.4 | No |
| 662 |  CHEMBL295532 | C33H35N7O2 | 561.69 | 7 / 1 | 5.4 | No |
| 1938 |  CHEMBL400424 | C24H23N7O2 | 441.495 | 6 / 2 | 3.9 | Yes |
| 2056 |  CHEMBL51634 | C26H26N6O | 438.535 | 5 / 1 | 5.6 | No |
| 2431 |  CHEMBL241684 | C23H21N7O2 | 427.468 | 6 / 1 | 3.4 | Yes |
| 7397 |  CHEMBL113714 | C23H24N2O5 | 408.454 | 6 / 3 | 3.4 | Yes |
| 10512 |  CHEMBL299151 | C28H33N5O3 | 487.604 | 6 / 1 | 5.2 | No |
| 11127 |  CHEMBL71410 | C24H21N7O2 | 439.479 | 7 / 3 | 4.1 | Yes |
| 11606 |  CHEMBL303264 | C24H20N6O3 | 440.463 | 7 / 2 | 4.1 | Yes |
| 12858 |  CHEMBL51712 | C27H26N6O2 | 466.545 | 6 / 1 | 5.5 | No |
| 12884 |  CHEMBL439743 | C24H26N2O5 | 422.481 | 6 / 2 | 3.7 | Yes |
| 13522 |  CHEMBL299340 | C27H26N6O2 | 466.545 | 6 / 2 | 5.5 | No |
| 15944 |  CHEMBL417366 | C22H22N2O5 | 394.427 | 6 / 3 | 3.0 | Yes |
| 21503 |  CHEMBL295959 | C30H31N6NaO2 | 530.608 | 7 / 0 | N/A | No |
| 24580 |  CHEMBL51689 | C25H22N6O2 | 438.491 | 6 / 1 | 4.0 | Yes |
| 24673 |  CHEMBL326086 | C22H22N6O3 | 418.457 | 7 / 3 | 2.6 | Yes |
| 26859 |  CHEMBL287374 | C33H28N8O2 | 568.641 | 7 / 2 | 5.2 | No |
| 26878 |  CHEMBL296719 | C36H33N7O2 | 595.707 | 7 / 1 | 6.3 | No |
| 28269 |  CHEMBL413163 | C48H70N14O11S | 1051.23 | 15 / 12 | -2.1 | No |
| 30023 |  CHEMBL299391 | C32H32N8O | 544.663 | 7 / 1 | 5.1 | No |
| 30444 |  BDBM50282882 | C32H29N9O3 | 587.644 | 9 / 2 | 3.7 | No |
| 31131 |  CHEMBL304032 | C21H20N6O2 | 388.431 | 5 / 2 | 2.7 | Yes |
| 31311 |  CHEMBL62936 | C28H26N6O2 | 478.556 | 5 / 1 | 4.4 | Yes |
| 31913 |  CHEMBL69221 | C25H19F3N6O3 | 508.461 | 10 / 1 | 5.1 | No |
| 33007 |  CHEMBL116094 | C23H24N6O3 | 432.484 | 7 / 3 | 2.9 | Yes |
| 33786 |  CHEMBL55366 | C26H24N6O2 | 452.518 | 6 / 1 | 3.8 | Yes |
| 36696 |  CHEMBL2058376 | C30H29F3N4O3S | 582.642 | 9 / 1 | 7.3 | No |
| 37373 |  CHEMBL302973 | C24H17F3N6O3 | 494.434 | 10 / 2 | 4.8 | Yes |
| 37588 |  CHEMBL295695 | C33H35N7O2 | 561.69 | 7 / 1 | 5.5 | No |
| 38199 |  CHEMBL62269 | C25H27N7O3 | 473.537 | 6 / 1 | 2.4 | Yes |
| 38945 |  CHEMBL54194 | C28H28N6O2 | 480.572 | 6 / 1 | 5.8 | No |
| 41642 |  CHEMBL49262 | C25H27N5O3 | 445.523 | 6 / 1 | 3.6 | Yes |
| 48521 |  CHEMBL303170 | C25H22N6O3 | 454.49 | 7 / 2 | 3.5 | Yes |
| 48837 |  CHEMBL299753 | C27H26N6O2 | 466.545 | 6 / 1 | 5.5 | No |
| 51500 |  CHEMBL298836 | C26H24N6O2 | 452.518 | 6 / 1 | 3.9 | Yes |
| 54284 |  CHEBI:58506 | C50H71N13O12 | 1046.2 | 13 / 12 | -0.4 | No |
| 61875 |  CHEMBL306670 | C18H18N4O5 | 370.365 | 6 / 1 | 4.6 | Yes |
| 66059 |  CHEMBL50092 | C21H20N2O5 | 380.4 | 6 / 3 | 2.6 | Yes |
| 66479 |  CHEMBL301072 | C28H28N6O2 | 480.572 | 6 / 1 | 5.8 | No |
| 67389 |  CHEMBL302815 | C27H26N6O3 | 482.544 | 7 / 1 | 5.3 | No |
| 69995 |  CHEMBL510065 | C35H31ClN6 | 571.125 | 3 / 1 | 8.2 | No |
| 70471 |  CHEMBL295959 | C30H31N6O2- | 507.618 | 7 / 0 | 4.2 | No |
| 70689 |  CHEMBL69475 | C18H18Br2N2O | 438.163 | 2 / 1 | 5.8 | No |
| 71283 |  CHEMBL262914 | C48H68N14O12 | 1033.16 | 15 / 12 | -0.7 | No |
| 72420 |  CHEMBL433895 | C26H25N7 | 435.535 | 5 / 1 | 4.9 | Yes |
| 72600 |  CHEMBL402669 | C70H103N13O13 | 1334.67 | 15 / 12 | 9.5 | No |
| 75538 |  CHEMBL245644 | C24H23N7O2 | 441.495 | 6 / 1 | 3.7 | Yes |
| 77412 |  CHEMBL115273 | C21H20N6O2 | 388.431 | 6 / 2 | 3.5 | Yes |
| 78562 |  CHEMBL124449 | C27H29N5O3 | 471.561 | 6 / 1 | 4.3 | Yes |
| 80806 |  CHEMBL128920 | C23H21N7O2 | 427.468 | 6 / 2 | 3.3 | Yes |
| 81007 |  CHEMBL265681 | C48H68N12O11 | 989.145 | 13 / 12 | 0.9 | No |
| 81009 |  CHEMBL411624 | C48H68N12O11 | 989.145 | 13 / 12 | 0.9 | No |
| 81213 |  CHEMBL26875 | C27H19N5O2S | 477.542 | 6 / 2 | 4.6 | Yes |
| 81461 |  CV-11194 | C26H24N6O2 | 452.518 | 6 / 2 | 5.1 | No |
| 82319 |  CHEMBL297714 | C34H36N6O2 | 560.702 | 6 / 1 | 5.9 | No |
| 86964 |  CHEMBL301547 | C36H39N7O3 | 617.754 | 8 / 1 | 5.8 | No |
| 87122 |  CHEMBL344093 | C30H30N6O3S | 554.669 | 8 / 1 | 5.3 | No |
| 87749 |  CHEMBL55939 | C27H26N6O2 | 466.545 | 6 / 1 | 4.3 | Yes |
| 88119 |  CHEMBL297583 | C34H31N7O3 | 585.668 | 8 / 1 | 5.7 | No |
| 90286 |  CHEMBL44605 | C35H37N7O4 | 619.726 | 9 / 1 | 5.0 | No |
| 91583 |  CHEMBL406888 | C66H101N13O13 | 1284.61 | 15 / 12 | 8.2 | No |
| 91969 |  CHEMBL52824 | C26H24N6O2 | 452.518 | 6 / 1 | 3.9 | Yes |
| 92871 |  CHEMBL129447 | C26H25N7O2 | 467.533 | 7 / 2 | 4.8 | Yes |
| 95823 |  CHEMBL309084 | C23H18N6O3 | 426.436 | 7 / 2 | 3.7 | Yes |
| 96965 |  CHEMBL304772 | C25H22N6O2S | 470.551 | 7 / 2 | 5.1 | No |
| 97908 |  CHEMBL51078 | C29H35N5O3 | 501.631 | 6 / 1 | 5.7 | No |
| 98431 |  CHEMBL64670 | C23H24N6O2 | 416.485 | 5 / 1 | 3.3 | Yes |
| 99179 |  pimobendan | C19H18N4O2 | 334.379 | 4 / 2 | 2.7 | Yes |
| 99739 |  CHEMBL69236 | C25H22N6O2S | 470.551 | 7 / 2 | 4.2 | Yes |
| 100498 |  CHEMBL69124 | C26H24N6O2 | 452.518 | 6 / 2 | 4.9 | Yes |
| 100812 |  CHEMBL295279 | C34H31N7O2S | 601.729 | 8 / 1 | 6.3 | No |
| 101589 |  CHEMBL123348 | C25H27N5O3 | 445.523 | 6 / 1 | 3.6 | Yes |
| 101958 |  CHEMBL65503 | C30H28N6O4 | 536.592 | 7 / 1 | 4.2 | No |
| 102406 |  CHEMBL439527 | C48H69N13O9S | 1004.22 | 13 / 12 | -0.5 | No |
| 102770 |  CHEMBL453934 | C35H34N6 | 538.699 | 3 / 1 | 6.4 | No |
| 103440 |  CHEMBL302811 | C26H25N7O2 | 467.533 | 7 / 3 | 5.0 | Yes |
| 104293 |  CHEMBL292316 | C23H24N6O2 | 416.485 | 5 / 1 | 3.4 | Yes |
| 104483 |  CHEMBL441649 | C22H20N6O4 | 432.44 | 8 / 3 | 3.4 | Yes |
| 104530 |  CHEMBL428475 | C48H69N13O10 | 988.161 | 13 / 12 | -1.0 | No |
| 104532 |  CHEMBL266899 | C48H69N13O10 | 988.161 | 13 / 12 | -1.0 | No |
| 106775 |  CHEMBL67636 | C26H24N6O2 | 452.518 | 6 / 2 | 5.0 | Yes |
| 107610 |  CHEMBL300279 | C31H33N7O3 | 551.651 | 8 / 2 | 4.0 | No |
| 107611 |  CHEMBL433278 | C31H33N7O3 | 551.651 | 8 / 2 | 4.0 | No |
| 107969 |  CHEMBL45805 | C33H33N7O4 | 591.672 | 9 / 2 | 2.5 | No |
| 108032 |  CHEMBL68622 | C27H26N6O3 | 482.544 | 7 / 1 | 5.3 | No |
| 108517 |  CHEMBL2058371 | C30H32N4O3S | 528.671 | 6 / 1 | 6.8 | No |
| 109164 |  CHEMBL51606 | C32H31N7O4 | 577.645 | 9 / 1 | 4.0 | No |
| 109165 |  CHEMBL298943 | C32H31N7O4 | 577.645 | 9 / 1 | 4.0 | No |
| 110224 |  CHEMBL52343 | C26H23ClN6O2 | 486.96 | 6 / 2 | 5.8 | No |
| 110853 |  CHEMBL51349 | C26H26N6O | 438.535 | 5 / 1 | 5.6 | No |
| 113720 |  CHEMBL53803 | C33H35N7O2 | 561.69 | 7 / 1 | 5.4 | No |
| 113721 |  CHEMBL52791 | C33H35N7O2 | 561.69 | 7 / 1 | 5.4 | No |
| 113737 |  CHEMBL300186 | C22H20N2O6 | 408.41 | 7 / 3 | 3.7 | Yes |
| 118081 |  CHEMBL112414 | C25H28N2O5 | 436.508 | 6 / 3 | 4.1 | Yes |
| 120041 |  CHEMBL268342 | C48H69N13O9 | 972.162 | 12 / 11 | -0.7 | No |
| 121261 |  CHEMBL294485 | C26H24N6O2 | 452.518 | 6 / 1 | 4.3 | Yes |
| 122517 |  CHEMBL358121 | C30H30N6O | 490.611 | 5 / 1 | 5.4 | No |
| 122723 |  CHEMBL115206 | C24H26N6O2 | 430.512 | 6 / 2 | 4.7 | Yes |
| 123055 |  CHEMBL298741 | C28H31N7 | 465.605 | 5 / 1 | 5.4 | No |
| 123477 |  CHEMBL216687 | C48H70N14O10 | 1003.18 | 14 / 13 | -1.7 | No |
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