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GLASS

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	5-hydroxytryptamine receptor 1B
Species	Mus musculus (Mouse)
Gene	Htr1b
Synonym	HTR1D2 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 5-HT1Dbeta 5-HT1DB 5-HT1B serotonin receptor 5-HT1B receptor 5-HT1B 5-HT-1B serotonin receptor 1B [ Show all ]
Disease	N/A for non-human GPCRs
Length	386
Amino acid sequence	MEEQGIQCAPPPPAASQTGVPLTNLSHNCSADGYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVEYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEMLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCAG
UniProt	P28334
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3708691
IUPHAR	2
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
536269	CHEMBL3915107	C21H23ClN2O3	386.876	4 / 0	3.4	Yes
26595	Yohimbine	C21H26N2O3	354.45	4 / 2	2.9	Yes
553558	spiperone	C23H26FN3O2	395.478	5 / 1	3.0	Yes
553684	Ketanserin	C22H22FN3O3	395.434	5 / 1	2.6	Yes
554109	S(-)-Pindolol	C14H20N2O2	248.326	3 / 3	1.8	Yes
163944	pindolol	C14H20N2O2	248.326	3 / 3	1.8	Yes
540373	CHEMBL3900699	C22H26N2O4	382.46	5 / 0	2.7	Yes
176700	RU 24969	C14H16N2O	228.295	2 / 2	1.8	Yes
554311	5-OH-Dpat	C16H25NO	247.382	2 / 1	4.1	Yes
289183	Cyanopindolol	C16H21N3O2	287.363	4 / 3	2.0	Yes
290310	serotonin	C10H12N2O	176.219	2 / 3	0.2	Yes
554945	mianserin	C18H20N2	264.372	2 / 0	3.4	Yes
375969	5-Carboxamidotryptamine	C11H13N3O	203.245	2 / 3	-0.6	Yes

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