You can:
| Name | Neuromedin-K receptor |
|---|---|
| Species | Cavia porcellus (Guinea pig) |
| Gene | TACR3 |
| Synonym | Neurokinin B receptor NK-3 receptor NK-3R NKR Tachykinin receptor 3 |
| Disease | N/A for non-human GPCRs |
| Length | 440 |
| Amino acid sequence | MASPAGNLSAWPGWGWPPPAALRNLTSSPAPTASPSPAPSWTPSPRPGPAHPFLQPPWAVALWSLAYGAVVAVAVLGNLVVIWIVLAHKRMRTVTNSFLVNLAFADAAMAALNALVNFIYALHGEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATRIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGSRQHFTYHMIVIVLVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYQEQLKAKRKVVKMMIIVVVTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIHVSSYDELELKATRLHPMRQSSLYTVTRMESMSVVFDSNDGDSARSSHQKRGTTRDVGSNVCSRRNSKSTSTTASFVSSSHMSVEEGS |
| UniProt | P30098 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3799 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 2498 |  Substance P | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
| 5215 |  CHEMBL296014 | C32H47N3O5 | 553.744 | 5 / 4 | 5.6 | No |
| 17568 |  ELEDOISIN | C54H85N13O15S | 1188.41 | 17 / 14 | -3.6 | No |
| 19023 |  GR-159897 | C23H27FN2O2S | 414.539 | 5 / 1 | 3.4 | Yes |
| 20866 |  CHEMBL449091 | C45H64N10O10 | 905.067 | 10 / 10 | 0.2 | No |
| 21972 |  L-Serine,N-[1-oxo-3-(2-pentylphenyl)propyl]-L-threonyl-(aE)-a,b-didehydro-N-methyltyrosyl-L-leucyl-D-phenylalanyl-L-allothreonyl-L-asparaginyl-,(7®1)-lactone | C54H72N8O13 | 1041.21 | 13 / 10 | 4.9 | No |
| 22460 |  CHEMBL303548 | C36H36N4O4 | 588.708 | 4 / 2 | 4.6 | No |
| 22469 |  L001421 | C36H36N4O4 | 588.708 | 4 / 2 | 4.6 | No |
| 24268 |  Talnetant | C25H22N2O2 | 382.463 | 3 / 2 | 5.7 | No |
| 36137 |  PD157672 | C32H47N5O5 | 581.758 | 5 / 5 | 4.5 | No |
| 36402 |  CHEMBL225297 | C39H47N9O7S | 785.921 | 10 / 7 | 1.2 | No |
| 37245 |  CHEMBL307433 | C45H66N10O10 | 907.083 | 10 / 10 | 0.8 | No |
| 50427 |  Substance P, C-terminal pentapeptide | C36H49N7O7S | 723.89 | 8 / 7 | 2.1 | No |
| 68123 |  CHEMBL2369767 | C43H59N9O9 | 845.999 | 9 / 9 | 1.3 | No |
| 72875 |  CHEMBL299377 | C35H41Cl2N3O2 | 606.632 | 3 / 0 | 7.0 | No |
| 72881 |  Osanetant | C35H41Cl2N3O2 | 606.632 | 3 / 0 | 7.0 | No |
| 78380 |  Substance P (5-11) | C41H60N10O9S | 869.052 | 11 / 10 | -0.5 | No |
| 80944 |  CHEMBL225588 | C44H54N8O6 | 790.966 | 8 / 6 | 3.1 | No |
| 81431 |  CP 96345 | C28H32N2O | 412.577 | 3 / 1 | 5.4 | No |
| 83593 |  CHEMBL306072 | C43H62N10O10S | 911.089 | 11 / 10 | -0.5 | No |
| 88826 |  CHEMBL583102 | C60H81N13O14S2 | 1272.51 | 18 / 13 | -0.8 | No |
| 116209 |  CHEMBL295301 | C33H48N4O5 | 580.77 | 5 / 4 | 5.3 | No |
| 118622 |  Senktide | C40H55N7O11S | 841.978 | 12 / 8 | 1.1 | No |
| 143279 |  CHEMBL45340 | C29H40F2N4O4 | 546.66 | 6 / 4 | 5.2 | No |
| 153732 |  CHEMBL389459 | C37H42N6O5 | 650.78 | 6 / 5 | 3.1 | No |
| 154322 |  CHEMBL567849 | C28H33Cl2F4N3O2 | 590.485 | 7 / 0 | 5.9 | No |
| 168490 |  CHEMBL225475 | C45H56N8O5 | 788.994 | 7 / 6 | 4.3 | No |
| 177259 |  CHEMBL124208 | C24H26FN3O2 | 407.489 | 4 / 1 | 4.0 | Yes |
| 184824 |  NKB [MePhe7] | C56H81N13O14S2 | 1224.46 | 18 / 13 | -1.4 | No |
| 193909 |  CHEMBL2369766 | C43H61N9O9 | 848.015 | 9 / 9 | 2.0 | No |
| 194773 |  CHEMBL33650 | C23H29N3O4 | 411.502 | 4 / 3 | 2.5 | Yes |
| 210345 |  CHEMBL32248 | C28H28N4O4 | 484.556 | 4 / 4 | 3.5 | Yes |
| 223775 |  Neurokinin B | C55H79N13O14S2 | 1210.43 | 18 / 14 | -1.6 | No |
| 223783 |  Neurokinin beta | C55H79N13O14S2 | 1210.43 | 18 / 14 | -1.6 | No |
| 252724 |  CHEMBL46795 | C35H40Cl2N2O6 | 655.613 | 7 / 1 | 5.6 | No |
| 252726 |  CHEMBL295785 | C35H40Cl2N2O6 | 655.613 | 7 / 1 | 5.6 | No |
| 252729 |  CHEMBL298247 | C35H40Cl2N2O6 | 655.613 | 7 / 1 | 5.6 | No |
| 252732 |  CHEMBL295615 | C35H40Cl2N2O6 | 655.613 | 7 / 1 | 5.6 | No |
| 254002 |  CHEMBL567198 | C27H34Cl3N3O2 | 538.938 | 3 / 0 | 5.5 | No |
| 259147 |  Saredutant | C31H35Cl2N3O2 | 552.54 | 3 / 1 | 5.9 | No |
| 259155 |  CHEMBL56835 | C31H35Cl2N3O2 | 552.54 | 3 / 1 | 5.9 | No |
| 261244 |  CHEMBL358863 | C21H24N2O | 320.436 | 2 / 2 | 3.6 | Yes |
| 267150 |  MEN-11558 | C33H35N5O4 | 565.674 | 4 / 5 | 3.3 | No |
| 267736 |  CHEMBL387506 | C38H44N6O5 | 664.807 | 6 / 6 | 3.4 | No |
| 297622 |  SB 235375 | C27H24N2O4 | 440.499 | 5 / 2 | 5.1 | No |
| 301359 |  CHEMBL295680 | C20H20N2O2 | 320.392 | 2 / 1 | 3.0 | Yes |
| 306969 |  CHEMBL2115416 | C34H38Cl2N2O6S | 673.646 | 8 / 0 | 4.7 | No |
| 306970 |  CHEMBL2114963 | C34H38Cl2N2O6S | 673.646 | 8 / 0 | 4.7 | No |
| 306973 |  CHEMBL2114965 | C34H38Cl2N2O6S | 673.646 | 8 / 0 | 4.7 | No |
| 306976 |  CHEMBL2115415 | C34H38Cl2N2O6S | 673.646 | 8 / 0 | 4.7 | No |
| 365943 |  CHEMBL59413 | C22H25FN2O2S | 400.512 | 5 / 2 | 3.4 | Yes |
| 376095 |  CHEMBL311917 | C36H50N6O7S | 710.891 | 8 / 6 | 2.6 | No |
| 378051 |  CHEMBL441040 | C18H19NO2 | 281.355 | 2 / 0 | 2.9 | Yes |
| 386340 |  CHEMBL372587 | C34H39Cl2N3O5 | 640.602 | 6 / 1 | 5.7 | No |
| 386346 |  MDL-105212 | C34H39Cl2N3O5 | 640.602 | 6 / 1 | 5.7 | No |
| 389291 |  PYR-GLN-PHE-PHE-GLY-LEU-MET-NH2 | C41H57N9O9S | 852.021 | 10 / 9 | 0.6 | No |
| 396245 |  CHEMBL565894 | C29H33Cl2F4N3O2 | 602.496 | 7 / 0 | 6.0 | No |
| 407616 |  ICIG 864 | C21H22N2O | 318.42 | 2 / 1 | 3.3 | Yes |
| 423420 |  CHEMBL81919 | C37H51N7O7S | 737.917 | 8 / 6 | 2.2 | No |
| 424068 |  CHEMBL47146 | C29H41FN4O4 | 528.669 | 5 / 4 | 5.1 | No |
| 431540 |  Burapitant | C31H35Cl2F6N3O3 | 682.529 | 10 / 1 | 6.2 | No |
| 440655 |  CHEMBL297327 | C32H47N3O5 | 553.744 | 5 / 4 | 5.6 | No |
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