You can:
| Name | Melanin-concentrating hormone receptor 1 |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Mchr1 |
| Synonym | SLC-1 {ECO:0000303|PubMed:11159839} MCHR-1 MCHR MCH1R MCH1 receptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 353 |
| Amino acid sequence | MDLQASLLSTGPNASNISDGQDNFTLAGPPPRTRSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT |
| UniProt | Q8JZL2 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4730 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 3663 |  CHEMBL216192 | C28H32N4O3 | 472.589 | 4 / 3 | 4.5 | Yes |
| 521610 |  CHEMBL3786346 | C25H26N4O4 | 446.507 | 7 / 0 | 2.5 | Yes |
| 9175 |  CHEMBL434747 | C30H40ClFN4O2 | 543.124 | 5 / 1 | 6.8 | No |
| 9258 |  CHEMBL196390 | C28H31N5O2 | 469.589 | 4 / 2 | 4.5 | Yes |
| 13740 |  CHEMBL188937 | C23H28N2O5 | 412.486 | 6 / 1 | 3.4 | Yes |
| 522032 |  CHEMBL3787261 | C25H28N4O5 | 464.522 | 8 / 1 | 2.2 | Yes |
| 21109 |  CHEMBL380509 | C28H33F5N4O | 536.591 | 8 / 1 | 5.1 | No |
| 25300 |  CHEMBL372721 | C26H28Cl2N4O | 483.437 | 3 / 1 | 5.3 | No |
| 522351 |  AZD-1979 | C25H26N4O5 | 462.506 | 8 / 0 | 2.0 | Yes |
| 27083 |  CHEMBL229715 | C29H36ClFN4O | 511.082 | 4 / 1 | 6.4 | No |
| 36676 |  CHEMBL211672 | C31H25F5N4 | 548.561 | 8 / 1 | 7.2 | No |
| 37337 |  CHEMBL190842 | C30H35F4N5O | 557.638 | 8 / 1 | 5.1 | No |
| 39411 |  CHEMBL373887 | C34H36N4O4 | 564.686 | 5 / 3 | 6.1 | No |
| 44133 |  CHEMBL424720 | C30H35N3O3 | 485.628 | 4 / 2 | 5.0 | Yes |
| 522927 |  CHEMBL3787170 | C22H23FN4O4 | 426.448 | 8 / 0 | 2.6 | Yes |
| 47993 |  CHEMBL424836 | C28H31N5O3 | 485.588 | 5 / 3 | 3.9 | Yes |
| 50595 |  CHEMBL383432 | C28H33ClF4N4O2 | 569.042 | 8 / 1 | 5.9 | No |
| 58862 |  CHEMBL197210 | C28H31N5O2 | 469.589 | 4 / 3 | 4.8 | Yes |
| 61322 |  CHEMBL208025 | C29H32F4N4O2 | 544.595 | 8 / 1 | 4.9 | No |
| 66106 |  CHEMBL206831 | C28H31F4N5O | 529.584 | 8 / 2 | 4.3 | No |
| 66559 |  CHEMBL208573 | C29H22F4N4O | 518.516 | 7 / 1 | 5.8 | No |
| 70801 |  CHEMBL215279 | C29H33N3O3 | 471.601 | 4 / 2 | 4.8 | Yes |
| 72354 |  CHEMBL425013 | C28H29N5O2 | 467.573 | 4 / 0 | 4.3 | Yes |
| 523802 |  US8685958, 5 | C26H28N4O5 | 476.533 | 8 / 0 | 2.5 | Yes |
| 84218 |  CHEMBL585664 | C27H28F2N4O3 | 494.543 | 8 / 0 | 2.3 | Yes |
| 90155 |  CHEMBL229823 | C28H35Cl2N5O | 528.522 | 4 / 1 | 6.6 | No |
| 91521 |  CHEMBL205979 | C28H36ClFN4O3S | 563.129 | 6 / 1 | 4.0 | No |
| 524184 |  CHEMBL3787134 | C22H24N4O4 | 408.458 | 7 / 0 | 2.5 | Yes |
| 92718 |  CHEMBL214177 | C24H31N3O3 | 409.53 | 4 / 2 | 3.6 | Yes |
| 95946 |  CHEMBL215841 | C23H29N3O3 | 395.503 | 4 / 2 | 3.2 | Yes |
| 97270 |  CHEMBL372291 | C26H27N5O2 | 441.535 | 4 / 2 | 4.1 | Yes |
| 106860 |  CHEMBL381162 | C25H32ClFN4OS | 491.066 | 5 / 1 | 4.4 | Yes |
| 106966 |  CHEMBL433596 | C27H24F4N4O2 | 512.509 | 8 / 2 | 4.5 | No |
| 524650 |  CHEMBL3785343 | C25H28N4O4 | 448.523 | 7 / 0 | 2.8 | Yes |
| 111947 |  CHEMBL203445 | C28H31F4N5O | 529.584 | 8 / 1 | 4.4 | No |
| 116583 |  CHEMBL204881 | C29H36F4N4O2 | 548.627 | 8 / 1 | 5.0 | No |
| 121386 |  CHEMBL191393 | C27H24F4N4O2 | 512.509 | 8 / 2 | 4.5 | No |
| 121703 |  CHEMBL388972 | C31H41Cl2N5O4S | 650.66 | 7 / 2 | 4.6 | No |
| 122475 |  CHEMBL229462 | C24H30ClFN4OS | 477.039 | 5 / 2 | 3.7 | Yes |
| 128168 |  CHEMBL206616 | C28H33F5N4O | 536.591 | 8 / 1 | 5.1 | No |
| 129063 |  CHEMBL206195 | C28H33ClF4N4O2 | 569.042 | 8 / 1 | 5.9 | No |
| 130502 |  CHEMBL203166 | C28H30F4N4O2 | 530.568 | 8 / 2 | 4.6 | No |
| 131189 |  CHEMBL215418 | C28H31BrN4O3 | 551.485 | 4 / 3 | 5.2 | No |
| 134097 |  CHEMBL187296 | C22H26N2O2 | 350.462 | 3 / 1 | 3.9 | Yes |
| 143436 |  CHEMBL229988 | C28H34ClFN4O2 | 513.054 | 5 / 2 | 5.0 | No |
| 145092 |  CHEMBL186825 | C28H30N2O4 | 458.558 | 5 / 1 | 4.6 | Yes |
| 145685 |  CHEMBL441886 | C23H29ClFN5OS | 478.027 | 6 / 2 | 3.1 | Yes |
| 525804 |  CHEMBL3787333 | C22H24N4O3 | 392.459 | 6 / 0 | 2.9 | Yes |
| 150604 |  CHEMBL196599 | C27H29N5O2 | 455.562 | 4 / 3 | 4.4 | Yes |
| 154109 |  CHEMBL214535 | C32H33N3O3 | 507.634 | 4 / 2 | 5.6 | No |
| 156601 |  CHEMBL390290 | C25H29ClFN3O2S | 490.034 | 5 / 1 | 4.9 | Yes |
| 158600 |  CHEMBL229223 | C29H34ClFN4O2 | 525.065 | 5 / 2 | 5.1 | No |
| 160774 |  CHEMBL193583 | C29H32N4O2 | 468.601 | 4 / 2 | 4.3 | Yes |
| 169958 |  CHEMBL197054 | C28H30N6O3 | 498.587 | 5 / 3 | 3.0 | Yes |
| 170366 |  CHEMBL195914 | C28H27N5O2 | 465.557 | 4 / 0 | 4.3 | Yes |
| 170464 |  CHEMBL190068 | C27H30ClFN4O2 | 497.011 | 5 / 2 | 4.3 | Yes |
| 170466 |  CHEMBL193164 | C27H30ClFN4O2 | 497.011 | 5 / 2 | 4.3 | Yes |
| 170470 |  CHEMBL193260 | C27H30ClFN4O2 | 497.011 | 5 / 2 | 4.3 | Yes |
| 173489 |  CHEMBL189496 | C20H20Cl2N2O3 | 407.291 | 4 / 1 | 4.4 | Yes |
| 178045 |  CHEMBL187503 | C28H27N3O3 | 453.542 | 5 / 1 | 4.4 | Yes |
| 180341 |  CHEMBL363336 | C27H28N2O3 | 428.532 | 4 / 1 | 4.7 | Yes |
| 184232 |  CHEMBL374844 | C25H29Cl2N5O | 486.441 | 4 / 2 | 5.3 | No |
| 184752 |  CHEMBL377843 | C32H28F4N4 | 544.598 | 7 / 1 | 7.1 | No |
| 184926 |  CHEMBL384626 | C29H34N4O3 | 486.616 | 4 / 2 | 4.7 | Yes |
| 527022 |  CHEMBL3786272 | C23H26N4O4 | 422.485 | 7 / 0 | 2.9 | Yes |
| 191325 |  CHEMBL378019 | C31H37F4N5O | 571.665 | 8 / 1 | 5.7 | No |
| 527262 |  CHEMBL3786841 | C26H28N4O5 | 476.533 | 8 / 0 | 2.4 | Yes |
| 204654 |  CHEMBL186333 | C21H21F3N2O4 | 422.404 | 8 / 1 | 4.3 | Yes |
| 206085 |  CHEMBL383798 | C26H27N5O2 | 441.535 | 4 / 2 | 4.1 | Yes |
| 207751 |  CHEMBL211820 | C30H26Cl2N4 | 513.466 | 3 / 1 | 7.4 | No |
| 208007 |  CHEMBL372570 | C27H29N5O2 | 455.562 | 4 / 2 | 4.1 | Yes |
| 211287 |  CHEMBL383340 | C29H37ClFN5O2 | 542.096 | 5 / 2 | 3.9 | No |
| 221475 |  CHEMBL215958 | C30H33N3O3 | 483.612 | 4 / 2 | 5.2 | No |
| 450458 |  CHEMBL229290 | C28H36ClFN4O3S | 563.129 | 6 / 2 | 4.0 | No |
| 228308 |  CHEMBL373886 | C34H36N4O3 | 548.687 | 4 / 3 | 6.2 | No |
| 229706 |  CHEMBL196115 | C29H33N5O3 | 499.615 | 5 / 2 | 4.4 | Yes |
| 233231 |  CHEMBL375520 | C29H36ClFN4O2 | 527.081 | 5 / 2 | 5.4 | No |
| 233233 |  CHEMBL229112 | C29H36ClFN4O2 | 527.081 | 5 / 2 | 5.4 | No |
| 234469 |  CHEMBL214280 | C28H31ClN4O3 | 507.031 | 4 / 3 | 5.2 | No |
| 236672 |  CHEMBL216561 | C30H36N4O2 | 484.644 | 4 / 3 | 5.1 | No |
| 240799 |  CHEMBL196991 | C26H34N6O | 446.599 | 4 / 2 | 3.1 | Yes |
| 241449 |  CHEMBL426292 | C26H27N5O2 | 441.535 | 4 / 2 | 4.1 | Yes |
| 243305 |  CHEMBL229461 | C24H26ClFN4OS | 473.007 | 5 / 1 | 4.9 | Yes |
| 245436 |  CHEMBL179501 | C28H30N4O2 | 454.574 | 4 / 1 | 4.3 | Yes |
| 248070 |  CHEMBL425744 | C27H29N5O2 | 455.562 | 4 / 2 | 4.1 | Yes |
| 249140 |  CHEMBL205397 | C26H28ClFN4O2 | 482.984 | 5 / 2 | 3.8 | Yes |
| 250230 |  CHEMBL381810 | C27H34ClFN4O | 485.044 | 4 / 1 | 4.7 | Yes |
| 254632 |  CHEMBL382668 | C30H34F4N4O | 542.623 | 7 / 1 | 6.1 | No |
| 259239 |  CHEMBL382631 | C27H28F4N4O2 | 516.541 | 8 / 2 | 4.1 | No |
| 528969 |  CHEMBL3670644 | C26H28N4O5 | 476.533 | 8 / 0 | 2.5 | Yes |
| 529126 |  US8685958, 8 | C25H26N4O4 | 446.507 | 7 / 0 | 2.4 | Yes |
| 265816 |  CHEMBL365714 | C28H30N2O4 | 458.558 | 5 / 1 | 4.6 | Yes |
| 267701 |  CHEMBL374843 | C28H33ClF2N4O | 515.046 | 5 / 1 | 6.0 | No |
| 272116 |  CHEMBL441726 | C24H26Cl2FN5O | 490.404 | 5 / 2 | 4.8 | Yes |
| 529289 |  CHEMBL3785663 | C24H24N4O4 | 432.48 | 7 / 0 | 2.1 | Yes |
| 273341 |  CHEMBL384247 | C28H31N3O4 | 473.573 | 5 / 2 | 5.1 | No |
| 274125 |  CHEMBL185688 | C28H30N2O4 | 458.558 | 5 / 1 | 4.6 | Yes |
| 279546 |  CHEMBL382177 | C27H33ClF2N4O | 503.035 | 5 / 1 | 4.8 | No |
| 281650 |  CHEMBL186469 | C21H24N2O4 | 368.433 | 5 / 1 | 3.1 | Yes |
| 529601 |  CHEMBL3786311 | C26H30N4O5 | 478.549 | 8 / 0 | 2.8 | Yes |
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