GPCR-I-TASSER results for Q71V90

[Click on Q71V90_results.tar.bz2 to download the tarball file including all modeling results listed on this page]

  Submitted Sequence

>Q71V90
KTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLC
TMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTL
TFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRIT
RMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFL
DENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHP

  Predicted Secondary Structure

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |               
KTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHP
PredictionCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCSSSSSCCSSSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
Conf.Score96768899999999999999689999999848887966788899999999999999999999998288855206544454667798766899999999997999880379869917998508982579999999999999999999999999999999983347898631430213045567799999999998799999999998745612599999999999999999898999997289999999998076468877677778777678997

  Predicted Solvent Accessibility

Sequence                  20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |               
KTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHP
Prediction83310040123030301010001010010037431223002111301131001010102003013001000100302331333100000000020000001010001203437432101020244433132011112132133332210120111001101434336544443341100000000002102101322010100200230433201100101020301230133100100004501420250033235435666444446435748
Values range from 0 (buried residue) to 9 (highly exposed residue)

  Top 5 Models predicted by GPCR-I-TASSER

Download Model 1 Download Model 2 Download Model 3 Download Model 4 Download Model 5
C-score=0.49
 C-score=-1.62
 C-score=-1.09
 C-score=-0.38
 C-score=-0.69
 
Estimated accuracy of Model1: 0.78±0.10 (TM-score)    5.0±3.2Å (RMSD)    (Read more about C-score of generated models)
Estimated local accuracy of Model1: The estiamted distances (between model and native structure, shown in 1st figure) for residues are more reliable for aligned (i.e., residues with high alignment coverage shown in 2nd figure) α-helix and β-strand regions.
Download estimated local accuracy of Model2, Model3, Model4, Model5

  Top 10 templates used by GPCR-I-TASSER

Rank PDB
Hit		Iden1Iden2Cov.Norm.
Z-score		Download
Align.		                   20                  40                  60                  80                 100                 120                 140                 160                 180                 200                 220                 240                 260
                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |                   |               
Sec.Str
Seq		CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCSSSSSCCSSSSSSCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
KTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHP
14dklA 0.96 0.90 0.92 3.47Download KTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRNIFEAYEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI----------------------
24dklA 0.96 0.90 0.92 3.00Download KTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRNIFEAYEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI----------------------
34djhA 0.70 0.65 0.91 2.55Download KTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVIECSLQFPDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVGTWDAYREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA-----ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------------------
44djhA 0.71 0.65 0.91 3.99Download KTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVIECSLQFPDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSAYREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSAA-----LSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------------------
54djhA 0.71 0.64 0.89 3.88Download KTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVIECSLQFPDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVR-----LLSDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA-----ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------------------
64djhA 0.72 0.65 0.91 2.44Download KTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVIECSLQFPDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGNREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSAAL-----SSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------------------
74djhA 0.72 0.64 0.89 3.69Download KTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVIECSLQFPDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLS-----DRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSA-----ALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------------------
84djhA 0.71 0.64 0.89 4.06Download KTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVRVDVIECSLQFPDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVR-----LLSDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSAA-----LSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------------------
94djhA 0.71 0.64 0.89 4.29Download KTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVIECSLQFPDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVR-----LLSDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSAA-----LSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCF---------------------P
104djhA 0.71 0.64 0.89 4.22Download KTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVIECSLQFPDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVR-----LLSDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSAA-----LSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFP---------------------
(a)All the residues are colored in black; however, those residues in template which are identical to the residue in the query sequence are highlighted in color. Coloring scheme is based on the property of amino acids, where polar are brightly coloured while non-polar residues are colored in dark shade. (more about the colors used)
(b)Rank of templates represents the top ten threading templates used by I-TASSER.
(c)Ident1 is the percentage sequence identity of the templates in the threading aligned region with the query sequence.
(d)Ident2 is the percentage sequence identity of the whole template chains with query sequence.
(e)Cov. represents the coverage of the threading alignment and is equal to the number of aligned residues divided by the length of query protein.
(f)Norm. Z-score is the normalized Z-score of the threading alignments. Alignment with a Normalized Z-score >1 mean a good alignment and vice versa.
(g)Download Align. provides the 3D structure of the aligned regions of the threading templates.
(h)The top 10 alignments reported above (in order of their ranking) are from the following threading programs:
       1: HHSEARCH   2: HHSEARCH2   3: wdPPAS   4: SP3   5: wdPPAS   6: SPARKS-X   7: Neff-PPAS   8: dPPAS   9: PROSPECT2   10: PPAS   


[Click on Q71V90_results.tar.bz2 to download the tarball file including all modeling results listed on this page]


 Please cite following article when you use the GPCR-I-TASSER server:
J Zhang, J Yang, R Jang, Y Zhang. GPCR-I-TASSER: A new hybrid approach to G protein-coupled receptor structure modeling with application to the human genome, submitted, 2014.