2011/10/15:
Visualization was enabled for the top 10 proteins analogous to the
I-TASSER models and for the enzyme commission predictions.
2011/10/09:
The function homology search was extended
to the entire PDB library. This helps increase the coverage and
accuracy of the structure-based function of the I-TASSER server.
2011/08/01:
The I-TASSER server had the 20,000th user registered (Congratulations!).
2011/03/28:
The first version of the I-TASSER Suite (Version 1.1) was publicly released
for download and installation. It is free for academic and non-profit
users.
2011/02/25:
The first beta-version of the I-TASSER standalone package
was ready for download and test.
2011/02/22:
A new message board was set up for the I-TASSER related Q&A discussions.
2010/12/20:
A new program, COFACTOR, was used for the structure-based protein function
predictions on ligand-binding site, enzyme number, and gene-ontology.
COFACTOR was ranked as the best method for function prediction in the
CASP9 experiment (Congratulations!).
2010/12/19:
A new Java-base viewer, Jmol, was used to display predicted models
and ligand-binding sites.
2010/11/18:
Solvent accessibility predictions were shown in the modeling result page.
2010/07/20:
A new option was added to allow users exclude specific proteins from
the I-TASSER template library.
2010/01/12:
The I-TASSER server was moved from the University of Kansas to
the University of Michigan Medical School. The new supercomputer cluster
at UM provides help in significant speeding up the I-TASSER modeling procedure.
2009/11/15:
Fragment Guided Molecular Dynamic simulations (FG-MD) were implemented on
I-TASSER models for steric clashes removal and local structure refinement.
2009/10/17:
A timer was added to the
Queue page to allow users track the implementation time of their
targets. A number of other changes were made in the Queue page for
improving the efficiency of retrieving I-TASSER output data.
2009/10/15:
A new interface
Search
was added to allow users to search targets
and predictions through the I-TASSER database.
2009/07/20:
Added features to allow users to assign external restraints
to guide the I-TASSER structural modeling. The user-specified information
includes:
2009/03/16:
Structure-based function predictions were developed
based on the global and local match of the predicted 3D models with
the known homolog and analog proteins. The function predictions
include ligand binding site, enzyme commission, and gene ontology.
2009/01/10:
Two new predictions were added in the output page: