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Add restraints to I-TASSER modeling


If users know some information about the structure of the modeled proteins, the information can be conveniently uploaded to the I-TASSER server. These information can substantially improve the quality of structural and function predictions. The I-TASSER server currently accepts two types of user-specified restraints: (1) inter-residue contant and distance restraints; (2) template structures and template-target alignments.

The server provides 4 convenient options to assign the restraints:

How to add inter-residue distance & contact restraints?

How to specify a template protein which I-TASSER modeling will be based on?

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