
LOMETS (Local Meta-Threading-Server) is an on-line web service
for protein structure prediction.
It generates 3D models by collecting high-scoring target-to-template alignments
from 8 locally-installed threading programs
(FUGUE, HHsearch, MUSTER, PPA, PROSPECT2, SAM-T02, SPARKS, SP3).
A detailed description of the server can been seen in
the Readme file.
The output of LOMETS includes
(see an illustrative example):
- The best 10 threading models selected from 160 models by the confidence score
- Top 10 target-template alignments of individual threading servers
- Prediction of spatial C-alpha and side-chain contact and distance map
- Full-length models built by MODELLER guided by consensus restraints
Reference:
S. Wu, Y. Zhang.
LOMETS: A local meta-threading-server for protein structure prediction.
Nucleic Acids Research 2007; 35: 3375-3382
(download the PDF file).
Click here
to download the benchmark set of 620 non-redundant proteins used by
LOMETS.
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