a request about TM-SCORE,STRUM.TM-align.

Hello,professor. I am a PHD from NANJING (Jiangsu province.China ).I am so sorry to bother you . But I met some problems on the applicatin on I-TASSER,STRUM which were developed by your team. In order to predict the protein of two similar amino-acid sequences (Identification and protein simulation of the single-amino-acid substitution;Ala/Thr).I want to find out whether there is any difference between in the two protein. but the problem is that the correlation between the results of TM-align. STRUM.and tm-score..could you please help? thank you , waiting for your reply..