BindProf is a method for predicting free energy changes (ΔΔG) of protein-protein binding interactions upon mutations of residues at the interface. While BindProf adopts a multi-scale approach using multiple sources of information at different levels of structural resolution, a unique feature of BindProf is the inclusion of an interface structural profile score derived from multiple structure alignments from analogous protein-protein interactions (>> read more about BindProf ...).
From May. 10 to Jul. 30, 2020 (CASP14 season), the BindProf server will be closed to external users. Jobs already submitted will not be affected. We apologize for any inconvenience this may cause.
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