Function Annotation for BL0023850

Receptor Information
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PDB ID 1iss
Chain A
Resolution 3.3 Å
UniProt ID P23385 (Metabotropic glutamate receptor 1)
Ligand Binding/Catalytic Sites
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Ligand Information
ID Name (Show Synonyms) Chemaxon Viewer Binding Affinity
MCG (S)-ALPHA-METHYL-4-CARBOXYPHENYLGLYCINE Kd=50000-540000nM, from BindingDB
IC50=4300-700000nM, from BindingDB
Ligand-Protein Interaction
Global View, download receptor, ligand Local View Binding Site Residues
Y74 S165 S186 T188 K409
Catalytic Site Residues N/A
Enzyme Commission
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EC Number Name
N/A N/A
Gene Ontology
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GO Terms Name Ontology
GO:0004930 G-protein coupled receptor activity Molecular Function
GO:0007186 G-protein coupled receptor signaling pathway Biological Process
GO:0016021 integral to membrane Cellular Component
External Links
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Reference:
Jianyi Yang, Ambrish Roy and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).