Function Annotation for BL0143731

Receptor Information
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PDB ID 3c59
Chain A
Resolution 2.3 Å
UniProt ID P43220 (Glucagon-like peptide 1 receptor)
Ligand Binding/Catalytic Sites
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Ligand Information
ID Name (Show Synonyms) Chemaxon Viewer Binding Affinity
III Peptide ligand (ASP, LEU, SER, LYS, GLN, MET, GLU, GLU, GLU, ALA, VAL, ARG, MET, PHE, ILE, GLU, TRP, LEU, LYS, ASN, GLY, GLY, PRO, SER, SER, GLY, ALA) N/A IC50=5nM, from PDBbind-CN
Ligand-Protein Interaction
Global View, download receptor, ligand Local View Binding Site Residues
V30 S31 L32 W39 E68 Y69 Y88 L89 P90 R121 E127 E128
Catalytic Site Residues N/A
Enzyme Commission
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EC Number Name
N/A N/A
Gene Ontology
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GO Terms Name Ontology
GO:0004930 G-protein coupled receptor activity Molecular Function
GO:0004967 glucagon receptor activity Molecular Function
GO:0007186 G-protein coupled receptor signaling pathway Biological Process
GO:0008528 G-protein coupled peptide receptor activity Molecular Function
GO:0016020 membrane Cellular Component
External Links
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Reference:
Jianyi Yang, Ambrish Roy and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).