Function Annotation for BL0152618

Receptor Information
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PDB ID 3eml
Chain A
Resolution 2.6 Å
UniProt ID P29274 (Adenosine receptor A2a)
Ligand Binding/Catalytic Sites
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Ligand Information
ID Name (Show Synonyms) Chemaxon Viewer Binding Affinity
ZMA 4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL Kd=1.8nM, from PDBbind-CN
Kd=0.1-64nM, from BindingDB
Kd=0.22nM, from BindingDB
Ligand-Protein Interaction
Global View, download receptor, ligand Local View Binding Site Residues
L85 F168 E169 M177 W246 L249 H250 N253 H264 L267 M270
Catalytic Site Residues
D1020 E1011
Enzyme Commission
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EC Number Name
N/A N/A
Gene Ontology
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GO Terms Name Ontology
GO:0003796 lysozyme activity Molecular Function
GO:0007186 G-protein coupled receptor signaling pathway Biological Process
GO:0009253 peptidoglycan catabolic process Biological Process
GO:0016021 integral to membrane Cellular Component
GO:0016998 cell wall macromolecule catabolic process Biological Process
External Links
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Reference:
Jianyi Yang, Ambrish Roy and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).