Function Annotation for BL0195884

Receptor Information
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PDB ID 3qak
Chain A
Resolution 2.71 Å
UniProt ID P29274 (Adenosine receptor A2a)
Ligand Binding/Catalytic Sites
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Ligand Information
ID Name (Show Synonyms) Chemaxon Viewer Binding Affinity
UKA 6-(2,2-DIPHENYLETHYLAMINO)-9-[(2R,3R,4S,5S)-5-(ETHYLCARBAMOYL)-3,4-DIHYDROXY-OXOLAN-2-YL]-N-[2-[(1-PYRIDIN-2-YLPIPERIDIN-4-YL)CARBAMOYLAMINO]ETHYL]PURINE-2-CARBOXAMIDE IC50=4nM, from BindingDB
Ligand-Protein Interaction
Global View, download receptor, ligand Local View Binding Site Residues
I66 V84 L85 T88 I92 L167 F168 E169 M177 W246 L249 H250 N253 T256 H264 L267 M270 Y271 I274 S277 H278
Catalytic Site Residues N/A
Enzyme Commission
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EC Number Name
3.2.1.17 Lysozyme
Gene Ontology
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GO Terms Name Ontology
GO:0003796 lysozyme activity Molecular Function
GO:0007186 G-protein coupled receptor signaling pathway Biological Process
GO:0009253 peptidoglycan catabolic process Biological Process
GO:0016021 integral to membrane Cellular Component
GO:0016998 cell wall macromolecule catabolic process Biological Process
External Links
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Reference:
Jianyi Yang, Ambrish Roy and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).