Function Annotation for BL0202179

Receptor Information
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PDB ID 3rze
Chain A
Resolution 3.1 Å
UniProt ID P35367 (Histamine H1 receptor)
Ligand Binding/Catalytic Sites
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Ligand Information
ID Name (Show Synonyms) Chemaxon Viewer Binding Affinity
D7V (3Z)-3-(DIBENZO[B,E]OXEPIN-11(6H)-YLIDENE)-N,N-DIMETHYLPROPAN-1-AMINE N/A
Ligand-Protein Interaction
Global View, download receptor, ligand Local View Binding Site Residues
D107 Y108 S111 T112 I115 W158 N198 W428 Y431 F432 F435 Y458
Catalytic Site Residues N/A
Enzyme Commission
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EC Number Name
3.2.1.17 Lysozyme
Gene Ontology
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GO Terms Name Ontology
GO:0003796 lysozyme activity Molecular Function
GO:0003824 catalytic activity Molecular Function
GO:0004871 signal transducer activity Molecular Function
GO:0004930 G-protein coupled receptor activity Molecular Function
GO:0004969 histamine receptor activity Molecular Function
GO:0005634 nucleus Cellular Component
GO:0005737 cytoplasm Cellular Component
GO:0005886 plasma membrane Cellular Component
GO:0005887 integral to plasma membrane Cellular Component
GO:0006954 inflammatory response Biological Process
GO:0007165 signal transduction Biological Process
GO:0007186 G-protein coupled receptor signaling pathway Biological Process
GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway Biological Process
GO:0007268 synaptic transmission Biological Process
GO:0008152 metabolic process Biological Process
GO:0009253 peptidoglycan catabolic process Biological Process
GO:0009629 response to gravity Biological Process
GO:0010894 negative regulation of steroid biosynthetic process Biological Process
GO:0016020 membrane Cellular Component
GO:0016021 integral to membrane Cellular Component
GO:0016787 hydrolase activity Molecular Function
GO:0016798 hydrolase activity, acting on glycosyl bonds Molecular Function
GO:0016998 cell wall macromolecule catabolic process Biological Process
GO:0019835 cytolysis Biological Process
GO:0032962 positive regulation of inositol trisphosphate biosynthetic process Biological Process
GO:0042742 defense response to bacterium Biological Process
GO:0045429 positive regulation of nitric oxide biosynthetic process Biological Process
GO:0045907 positive regulation of vasoconstriction Biological Process
GO:0048016 inositol phosphate-mediated signaling Biological Process
GO:0051381 histamine binding Molecular Function
GO:0071420 cellular response to histamine Biological Process
GO:0005730 nucleolus Cellular Component
External Links
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Reference:
Jianyi Yang, Ambrish Roy and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).