Function Annotation for BL0217099

Receptor Information
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PDB ID 3vw7
Chain A
Resolution 2.2 Å
UniProt ID P25116 (Proteinase-activated receptor 1)
Ligand Binding/Catalytic Sites
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Ligand Information
ID Name (Show Synonyms) Chemaxon Viewer Binding Affinity
VPX ETHYL [(1R,3AR,4AR,6R,8AR,9S,9AS)-9-{(E)-2-[5-(3- FLUOROPHENYL)PYRIDIN-2-YL]ETHENYL}-1-METHYL-3- OXODODECAHYDRONAPHTHO[2,3-C]FURAN-6-YL]CARBAMATE;VORAPAXAR N/A
Ligand-Protein Interaction
Global View, download receptor, ligand Local View Binding Site Residues
Y183 Y187 G233 P236 L237 H255 D256 V257 L258 F271 L332 L333 H336 Y337 L340 A349 Y350 Y353
Catalytic Site Residues N/A
Enzyme Commission
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EC Number Name
3.2.1.17 Lysozyme
Gene Ontology
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GO Terms Name Ontology
GO:0042742 defense response to bacterium Biological Process
GO:0016998 cell wall macromolecule catabolic process Biological Process
GO:0016787 hydrolase activity Molecular Function
GO:0009253 peptidoglycan catabolic process Biological Process
GO:0008152 metabolic process Biological Process
GO:0003796 lysozyme activity Molecular Function
GO:0019835 cytolysis Biological Process
GO:0016798 hydrolase activity, acting on glycosyl bonds Molecular Function
GO:0003824 catalytic activity Molecular Function
External Links
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Reference:
Jianyi Yang, Ambrish Roy and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).