Function Annotation for BL0224693

Receptor Information
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PDB ID 4djh
Chain A
Resolution 2.9 Å
UniProt ID P41145 (Kappa-type opioid receptor)
Ligand Binding/Catalytic Sites
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Ligand Information
ID Name (Show Synonyms) Chemaxon Viewer Binding Affinity
JDC (3R)-7-HYDROXY-N-{(2S)-1-[(3R,4R)-4-(3-HYDROXYPHENYL)-3,4-DIMETHYLPIPERIDIN-1-YL]-3-METHYLBUTAN-2-YL}-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXAMIDE N/A
Ligand-Protein Interaction
Global View, download receptor, ligand Local View Binding Site Residues
V108 T111 Q115 W124 V134 L135 D138 Y139 M142 K227 V230 W287 I290 I294 I316 G319 Y320
Catalytic Site Residues N/A
Enzyme Commission
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EC Number Name
N/A N/A
Gene Ontology
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GO Terms Name Ontology
GO:0003796 lysozyme activity Molecular Function
GO:0003824 catalytic activity Molecular Function
GO:0007186 G-protein coupled receptor signaling pathway Biological Process
GO:0008152 metabolic process Biological Process
GO:0009253 peptidoglycan catabolic process Biological Process
GO:0016021 integral to membrane Cellular Component
GO:0016787 hydrolase activity Molecular Function
GO:0016798 hydrolase activity, acting on glycosyl bonds Molecular Function
GO:0016998 cell wall macromolecule catabolic process Biological Process
GO:0019835 cytolysis Biological Process
GO:0042742 defense response to bacterium Biological Process
External Links
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Reference:
Jianyi Yang, Ambrish Roy and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).