gene name common name UniProt entry (canonical isoform) COFACTOR (MF) COFACTOR (BP) COFACTOR (CC) Function description UniProt-GOA (non-IEA) UniProtGOA (IEA only) UniProt annotation score NextProt (GOLD) NextProt (SILVER) chromosome location tissue-specific protein expression tissue-specific RNA expression sequence FAM57A FAM57A FA57A_HUMAN (Q8TBR7-2) GO:0016740 (1.00) ! transferase activity; GO:0050291 (0.99) ! sphingosine N-acyltransferase activity; GO:0042277 (0.21) ! peptide binding; GO:0004985 (0.21) ! opioid receptor activity; GO:1901338 (0.20) ! catecholamine binding; GO:0050780 (0.20) ! dopamine receptor binding; GO:0008227 (0.20) ! G-protein coupled amine receptor activity; GO:0004952 (0.20) ! dopamine neurotransmitter receptor activity; GO:0042802 (0.18) ! identical protein binding; GO:0020037 (0.18) ! heme binding; GO:0019899 (0.18) ! enzyme binding; GO:0009055 (0.18) ! electron carrier activity; GO:0005506 (0.18) ! iron ion binding; GO:0003796 (0.18) ! lysozyme activity; GO:0001609 (0.18) ! G-protein coupled adenosine receptor activity; GO:0051377 (0.01) ! mannose-ethanolamine phosphotransferase activity GO:0044763 (0.99) ! single-organism cellular process; GO:0032502 (0.69) ! developmental process; GO:0044767 (0.64) ! single-organism developmental process; GO:0048856 (0.59) ! anatomical structure development; GO:1901564 (0.57) ! organonitrogen compound metabolic process; GO:0044237 (0.57) ! cellular metabolic process; GO:0006629 (0.57) ! lipid metabolic process; GO:0048869 (0.55) ! cellular developmental process; GO:0016043 (0.54) ! cellular component organization; GO:0007420 (0.54) ! brain development; GO:0021952 (0.53) ! central nervous system projection neuron axonogenesis; GO:0001654 (0.53) ! eye development; GO:0006672 (0.46) ! ceramide metabolic process; GO:0046467 (0.42) ! membrane lipid biosynthetic process; GO:0046513 (0.41) ! ceramide biosynthetic process; GO:0050794 (0.32) ! regulation of cellular process; GO:0048523 (0.31) ! negative regulation of cellular process; GO:0045596 (0.28) ! negative regulation of cell differentiation; GO:0050896 (0.27) ! response to stimulus; GO:0006950 (0.26) ! response to stress; GO:0006954 (0.25) ! inflammatory response; GO:1901615 (0.24) ! organic hydroxy compound metabolic process; GO:1901360 (0.24) ! organic cyclic compound metabolic process; GO:0080090 (0.23) ! regulation of primary metabolic process; GO:0060255 (0.23) ! regulation of macromolecule metabolic process; GO:0031323 (0.23) ! regulation of cellular metabolic process; GO:0071702 (0.22) ! organic substance transport; GO:0070887 (0.22) ! cellular response to chemical stimulus; GO:0065009 (0.22) ! regulation of molecular function; GO:0065008 (0.22) ! regulation of biological quality; GO:0051649 (0.22) ! establishment of localization in cell; GO:0044260 (0.22) ! cellular macromolecule metabolic process; GO:0032268 (0.22) ! regulation of cellular protein metabolic process; GO:0031324 (0.22) ! negative regulation of cellular metabolic process; GO:0030534 (0.22) ! adult behavior; GO:0010605 (0.22) ! negative regulation of macromolecule metabolic process; GO:0010033 (0.22) ! response to organic substance; GO:0009636 (0.22) ! response to toxic substance; GO:0009628 (0.22) ! response to abiotic stimulus; GO:0006811 (0.22) ! ion transport; GO:0006355 (0.22) ! regulation of transcription, DNA-templated; GO:2000113 (0.21) ! negative regulation of cellular macromolecule biosynthetic process; GO:1901700 (0.21) ! response to oxygen-containing compound; GO:0098810 (0.21) ! neurotransmitter reuptake; GO:0071705 (0.21) ! nitrogen compound transport; GO:0070848 (0.21) ! response to growth factor; GO:0051931 (0.21) ! regulation of sensory perception; GO:0051705 (0.21) ! multi-organism behavior; GO:0051703 (0.21) ! intraspecies interaction between organisms; GO:0051091 (0.21) ! positive regulation of sequence-specific DNA binding transcription factor activity; GO:0050905 (0.21) ! neuromuscular process; GO:0050881 (0.21) ! musculoskeletal movement; GO:0046942 (0.21) ! carboxylic acid transport; GO:0045934 (0.21) ! negative regulation of nucleobase-containing compound metabolic process; GO:0043086 (0.21) ! negative regulation of catalytic activity; GO:0042391 (0.21) ! regulation of membrane potential; GO:0036294 (0.21) ! cellular response to decreased oxygen levels; GO:0033554 (0.21) ! cellular response to stress; GO:0033135 (0.21) ! regulation of peptidyl-serine phosphorylation; GO:0032459 (0.21) ! regulation of protein oligomerization; GO:0031333 (0.21) ! negative regulation of protein complex assembly; GO:0007631 (0.21) ! feeding behavior; GO:0006869 (0.21) ! lipid transport; GO:0006816 (0.21) ! calcium ion transport; GO:0006606 (0.21) ! protein import into nucleus; GO:0001934 (0.21) ! positive regulation of protein phosphorylation; GO:0001666 (0.21) ! response to hypoxia; GO:2000650 (0.20) ! negative regulation of sodium ion transmembrane transporter activity; GO:1903963 (0.20) ! arachidonate transport; GO:1903531 (0.20) ! negative regulation of secretion by cell; GO:1902532 (0.20) ! negative regulation of intracellular signal transduction; GO:0097305 (0.20) ! response to alcohol; GO:0090068 (0.20) ! positive regulation of cell cycle process; GO:0090066 (0.20) ! regulation of anatomical structure size; GO:0072503 (0.20) ! cellular divalent inorganic cation homeostasis; GO:0071310 (0.20) ! cellular response to organic substance; GO:0060159 (0.20) ! regulation of dopamine receptor signaling pathway; GO:0060004 (0.20) ! reflex; GO:0055074 (0.20) ! calcium ion homeostasis; GO:0051940 (0.20) ! regulation of catecholamine uptake involved in synaptic transmission; GO:0051896 (0.20) ! regulation of protein kinase B signaling; GO:0051785 (0.20) ! positive regulation of nuclear division; GO:0051781 (0.20) ! positive regulation of cell division; GO:0051583 (0.20) ! dopamine uptake involved in synaptic transmission; GO:0051350 (0.20) ! negative regulation of lyase activity; GO:0051224 (0.20) ! negative regulation of protein transport; GO:0051047 (0.20) ! positive regulation of secretion; GO:0050802 (0.20) ! circadian sleep/wake cycle, sleep; GO:0050708 (0.20) ! regulation of protein secretion; GO:0050433 (0.20) ! regulation of catecholamine secretion; GO:0048713 (0.20) ! regulation of oligodendrocyte differentiation; GO:0048638 (0.20) ! regulation of developmental growth; GO:0045931 (0.20) ! positive regulation of mitotic cell cycle; GO:0045893 (0.20) ! positive regulation of transcription, DNA-templated; GO:0045892 (0.20) ! negative regulation of transcription, DNA-templated; GO:0045745 (0.20) ! positive regulation of G-protein coupled receptor protein signaling pathway; GO:0045686 (0.20) ! negative regulation of glial cell differentiation; GO:0042749 (0.20) ! regulation of circadian sleep/wake cycle; GO:0042127 (0.20) ! regulation of cell proliferation; GO:0035813 (0.20) ! regulation of renal sodium excretion; GO:0035482 (0.20) ! gastric motility; GO:0035264 (0.20) ! multicellular organism growth; GO:0032846 (0.20) ! positive regulation of homeostatic process; GO:0032465 (0.20) ! regulation of cytokinesis; GO:0032415 (0.20) ! regulation of sodium:proton antiporter activity; GO:0032309 (0.20) ! icosanoid secretion; GO:0032225 (0.20) ! regulation of synaptic transmission, dopaminergic; GO:0032102 (0.20) ! negative regulation of response to external stimulus; GO:0031987 (0.20) ! locomotion involved in locomotory behavior; GO:0031623 (0.20) ! receptor internalization; GO:0031280 (0.20) ! negative regulation of cyclase activity; GO:0030818 (0.20) ! negative regulation of cAMP biosynthetic process; GO:0014075 (0.20) ! response to amine; GO:0014072 (0.20) ! response to isoquinoline alkaloid; GO:0014046 (0.20) ! dopamine secretion; GO:0009057 (0.20) ! macromolecule catabolic process; GO:0007088 (0.20) ! regulation of mitotic nuclear division; GO:0006875 (0.20) ! cellular metal ion homeostasis; GO:0006584 (0.20) ! catecholamine metabolic process; GO:0006357 (0.20) ! regulation of transcription from RNA polymerase II promoter; GO:0003081 (0.20) ! regulation of systemic arterial blood pressure by renin-angiotensin; GO:0002029 (0.20) ! desensitization of G-protein coupled receptor protein signaling pathway; GO:0001964 (0.20) ! startle response; GO:1903524 (0.19) ! positive regulation of blood circulation; GO:1901135 (0.19) ! carbohydrate derivative metabolic process; GO:0072677 (0.19) ! eosinophil migration; GO:0071621 (0.19) ! granulocyte chemotaxis; GO:0071417 (0.19) ! cellular response to organonitrogen compound; GO:0071407 (0.19) ! cellular response to organic cyclic compound; GO:0060732 (0.19) ! positive regulation of inositol phosphate biosynthetic process; GO:0050803 (0.19) ! regulation of synapse structure or activity; GO:0044248 (0.19) ! cellular catabolic process; GO:0032960 (0.19) ! regulation of inositol trisphosphate biosynthetic process; GO:0019932 (0.19) ! second-messenger-mediated signaling; GO:0019229 (0.19) ! regulation of vasoconstriction; GO:0009416 (0.19) ! response to light stimulus; GO:0008306 (0.19) ! associative learning; GO:0042742 (0.18) ! defense response to bacterium; GO:0022900 (0.18) ! electron transport chain; GO:0019835 (0.18) ! cytolysis; GO:0019076 (0.18) ! viral release from host cell; GO:0016998 (0.18) ! cell wall macromolecule catabolic process; GO:0010579 (0.18) ! positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; GO:0009253 (0.18) ! peptidoglycan catabolic process; GO:0008542 (0.18) ! visual learning; GO:0007596 (0.18) ! blood coagulation; GO:0007200 (0.18) ! phospholipase C-activating G-protein coupled receptor signaling pathway; GO:0006968 (0.18) ! cellular defense response; GO:0006915 (0.18) ! apoptotic process; GO:0006909 (0.18) ! phagocytosis; GO:0001973 (0.18) ! adenosine receptor signaling pathway; GO:0045599 (0.10) ! negative regulation of fat cell differentiation; GO:0006644 (0.06) ! phospholipid metabolic process; GO:0008203 (0.05) ! cholesterol metabolic process; GO:0007399 (0.05) ! nervous system development; GO:0019538 (0.03) ! protein metabolic process; GO:0044267 (0.02) ! cellular protein metabolic process; GO:0030163 (0.02) ! protein catabolic process; GO:0001302 (0.02) ! replicative cell aging; GO:0072721 (0.01) ! cellular response to dithiothreitol; GO:0071492 (0.01) ! cellular response to UV-A; GO:0060052 (0.01) ! neurofilament cytoskeleton organization; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0051974 (0.01) ! negative regulation of telomerase activity; GO:0051935 (0.01) ! glutamate reuptake; GO:0050885 (0.01) ! neuromuscular process controlling balance; GO:0050884 (0.01) ! neuromuscular process controlling posture; GO:0045861 (0.01) ! negative regulation of proteolysis; GO:0045494 (0.01) ! photoreceptor cell maintenance; GO:0044257 (0.01) ! cellular protein catabolic process; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0036146 (0.01) ! cellular response to mycotoxin; GO:0035690 (0.01) ! cellular response to drug; GO:0035176 (0.01) ! social behavior; GO:0021523 (0.01) ! somatic motor neuron differentiation; GO:0008361 (0.01) ! regulation of cell size; GO:0007628 (0.01) ! adult walking behavior; GO:0007601 (0.01) ! visual perception; GO:0007040 (0.01) ! lysosome organization; GO:0007006 (0.01) ! mitochondrial membrane organization; GO:0006506 (0.01) ! GPI anchor biosynthetic process; GO:0001306 (0.01) ! age-dependent response to oxidative stress GO:0005887 (1.00) ! integral component of plasma membrane; GO:0005886 (1.00) ! plasma membrane; GO:0044444 (0.99) ! cytoplasmic part; GO:0043229 (0.99) ! intracellular organelle; GO:0043227 (0.99) ! membrane-bounded organelle; GO:0005783 (0.98) ! endoplasmic reticulum; GO:0097458 (0.37) ! neuron part; GO:0042995 (0.37) ! cell projection; GO:0098590 (0.29) ! plasma membrane region; GO:0044463 (0.29) ! cell projection part; GO:0005794 (0.29) ! Golgi apparatus; GO:0005737 (0.29) ! cytoplasm; GO:0043005 (0.25) ! neuron projection; GO:0030430 (0.25) ! host cell cytoplasm; GO:0044456 (0.22) ! synapse part; GO:0030425 (0.22) ! dendrite; GO:0030054 (0.22) ! cell junction; GO:0045211 (0.15) ! postsynaptic membrane; GO:0045202 (0.15) ! synapse; GO:0044297 (0.15) ! cell body; GO:0043679 (0.15) ! axon terminus; GO:0043025 (0.12) ! neuronal cell body; GO:0042597 (0.12) ! periplasmic space; GO:0032279 (0.12) ! asymmetric synapse; GO:0005768 (0.12) ! endosome; GO:0044446 (0.10) ! intracellular organelle part; GO:0005793 (0.10) ! endoplasmic reticulum-Golgi intermediate compartment; GO:0045121 (0.09) ! membrane raft; GO:0042383 (0.09) ! sarcolemma; GO:0031253 (0.09) ! cell projection membrane; GO:0005769 (0.09) ! early endosome; GO:0043234 (0.08) ! protein complex; GO:0097381 (0.06) ! photoreceptor disc membrane; GO:0060342 (0.06) ! photoreceptor inner segment membrane; GO:0043235 (0.06) ! receptor complex; GO:0043197 (0.06) ! dendritic spine; GO:0042622 (0.06) ! photoreceptor outer segment membrane; GO:0032809 (0.06) ! neuronal cell body membrane; GO:0032280 (0.06) ! symmetric synapse; GO:0031982 (0.06) ! vesicle; GO:0030424 (0.06) ! axon; GO:0016324 (0.06) ! apical plasma membrane; GO:0009986 (0.06) ! cell surface; GO:0005911 (0.06) ! cell-cell junction; GO:0005901 (0.06) ! caveola; GO:0005764 (0.06) ! lysosome; GO:0005634 (0.06) ! nucleus; GO:0001917 (0.06) ! photoreceptor inner segment; GO:0001750 (0.06) ! photoreceptor outer segment; GO:0000139 (0.06) ! Golgi membrane; GO:0005789 (0.04) ! endoplasmic reticulum membrane; GO:0071944 (0.03) ! cell periphery; GO:0045177 (0.03) ! apical part of cell; GO:0032590 (0.03) ! dendrite membrane; GO:0030867 (0.03) ! rough endoplasmic reticulum membrane; GO:0030660 (0.03) ! Golgi-associated vesicle membrane; GO:0030139 (0.03) ! endocytic vesicle; GO:0016323 (0.03) ! basolateral plasma membrane; GO:0014069 (0.03) ! postsynaptic density; GO:0009897 (0.03) ! external side of plasma membrane; GO:0005829 (0.03) ! cytosol; GO:0005654 (0.03) ! nucleoplasm; GO:0061576 (0.02) ! acyl-CoA ceramide synthase complex GO:0005886 ! plasma membrane; GO:0005515 ! protein binding GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 GO:0005515 ! protein binding 732412-742972 (17p13.3) Skin - Not Sun Exposed (Suprapubic): 100.10; Skin - Sun Exposed (Lower leg): 82.99; Cells - Transformed fibroblasts: 40.88; Esophagus - Mucosa: 31.07; Vagina: 30.35; Cells - EBV-transformed lymphocytes: 25.44; Testis: 19.01; Cervix - Ectocervix: 18.05; Pituitary: 16.76; Prostate: 16.61; Bladder: 16.54; Cervix - Endocervix: 16.34; Stomach: 15.38; Minor Salivary Gland: 15.32; Nerve - Tibial: 14.37; Brain - Cerebellum: 13.71; Brain - Cerebellar Hemisphere: 13.55; Fallopian Tube: 13.53; Uterus: 12.82; Thyroid: 12.66; Lung: 11.68; Ovary: 11.06; Artery - Aorta: 10.85; Adipose - Visceral (Omentum): 10.33; Artery - Coronary: 10.08; Breast - Mammary Tissue: 8.65; Small Intestine - Terminal Ileum: 8.53; Adipose - Subcutaneous: 8.52; Esophagus - Gastroesophageal Junction: 7.72; Esophagus - Muscularis: 7.70; Colon - Transverse: 7.62; Artery - Tibial: 7.52; Colon - Sigmoid: 7.13; Brain - Hypothalamus: 6.04; Brain - Frontal Cortex (BA9): 5.93; Brain - Cortex: 5.89; Brain - Anterior cingulate cortex (BA24): 5.04; Spleen: 5.00; Brain - Amygdala: 4.96; Brain - Nucleus accumbens (basal ganglia): 4.93; Kidney - Cortex: 4.79; Pancreas: 4.79; Brain - Caudate (basal ganglia): 4.42; Brain - Hippocampus: 4.20; Brain - Substantia nigra: 4.05; Heart - Atrial Appendage: 3.92; Adrenal Gland: 3.82; Brain - Putamen (basal ganglia): 3.78; Brain - Spinal cord (cervical c-1): 3.61; Heart - Left Ventricle: 1.89; Liver: 1.20; Muscle - Skeletal: 1.12; Whole Blood: 0.50; MLLTLAGGALFFPGLFALCTWALRRSQPGWSRTDCVMISTRLVSSVHAVLATGSGIVIIRSCDDVITGRHWLAREYVWFLIPYMIYDSYAMYLCEWCRTRDQNRAPSLTLRNFLSRNRLMITHHAVILFVLVPVAQRLRGDLGDFFVGCIFTAELSTPFVSLGRVLIQLKQQHTLLYKVNGILTLATFLSCRILLFPFMYWSYGRQQGLSLLQVPFSIPFYCNVANAFLVAPQIYWFCLLCRKAVRLFDTPQAKKDG TLCD2 TLC domain-containing protein 2 TLCD2_HUMAN (A6NGC4-1) GO:0016740 (0.86) ! transferase activity; GO:0050291 (0.76) ! sphingosine N-acyltransferase activity; GO:0005216 (0.59) ! ion channel activity; GO:0009881 (0.55) ! photoreceptor activity; GO:0051377 (0.05) ! mannose-ethanolamine phosphotransferase activity; GO:0008757 (0.05) ! S-adenosylmethionine-dependent methyltransferase activity GO:0044763 (0.97) ! single-organism cellular process; GO:0008152 (0.90) ! metabolic process; GO:0071704 (0.89) ! organic substance metabolic process; GO:0044238 (0.89) ! primary metabolic process; GO:0044237 (0.89) ! cellular metabolic process; GO:0006643 (0.76) ! membrane lipid metabolic process; GO:0006672 (0.73) ! ceramide metabolic process; GO:0044765 (0.61) ! single-organism transport; GO:0050794 (0.60) ! regulation of cellular process; GO:0006811 (0.60) ! ion transport; GO:0034220 (0.58) ! ion transmembrane transport; GO:0019538 (0.58) ! protein metabolic process; GO:0044267 (0.56) ! cellular protein metabolic process; GO:0050896 (0.55) ! response to stimulus; GO:0006464 (0.54) ! cellular protein modification process; GO:0018298 (0.53) ! protein-chromophore linkage; GO:0007602 (0.53) ! phototransduction; GO:0032502 (0.52) ! developmental process; GO:0048856 (0.50) ! anatomical structure development; GO:0046467 (0.48) ! membrane lipid biosynthetic process; GO:0046513 (0.46) ! ceramide biosynthetic process; GO:0015992 (0.40) ! proton transport; GO:0006644 (0.34) ! phospholipid metabolic process; GO:0008203 (0.31) ! cholesterol metabolic process; GO:0007399 (0.31) ! nervous system development; GO:0048869 (0.24) ! cellular developmental process; GO:0016043 (0.24) ! cellular component organization; GO:0032989 (0.21) ! cellular component morphogenesis; GO:0021952 (0.19) ! central nervous system projection neuron axonogenesis; GO:0007420 (0.19) ! brain development; GO:0001654 (0.19) ! eye development; GO:0048523 (0.11) ! negative regulation of cellular process; GO:0080090 (0.07) ! regulation of primary metabolic process; GO:0071702 (0.07) ! organic substance transport; GO:0060255 (0.07) ! regulation of macromolecule metabolic process; GO:0031323 (0.07) ! regulation of cellular metabolic process; GO:0030163 (0.07) ! protein catabolic process; GO:0009247 (0.05) ! glycolipid biosynthetic process; GO:0060052 (0.04) ! neurofilament cytoskeleton organization; GO:0060041 (0.04) ! retina development in camera-type eye; GO:0051935 (0.04) ! glutamate reuptake; GO:0050885 (0.04) ! neuromuscular process controlling balance; GO:0050884 (0.04) ! neuromuscular process controlling posture; GO:0050881 (0.04) ! musculoskeletal movement; GO:0045861 (0.04) ! negative regulation of proteolysis; GO:0045494 (0.04) ! photoreceptor cell maintenance; GO:0044257 (0.04) ! cellular protein catabolic process; GO:0043066 (0.04) ! negative regulation of apoptotic process; GO:0035176 (0.04) ! social behavior; GO:0021523 (0.04) ! somatic motor neuron differentiation; GO:0008361 (0.04) ! regulation of cell size; GO:0008306 (0.04) ! associative learning; GO:0007628 (0.04) ! adult walking behavior; GO:0007601 (0.04) ! visual perception; GO:0007040 (0.04) ! lysosome organization; GO:0007006 (0.04) ! mitochondrial membrane organization; GO:0006869 (0.04) ! lipid transport; GO:0001306 (0.04) ! age-dependent response to oxidative stress; GO:0045599 (0.03) ! negative regulation of fat cell differentiation; GO:0032259 (0.03) ! methylation; GO:0006355 (0.03) ! regulation of transcription, DNA-templated; GO:0046476 (0.02) ! glycosylceramide biosynthetic process; GO:0044182 (0.02) ! filamentous growth of a population of unicellular organisms; GO:0009826 (0.02) ! unidimensional cell growth; GO:0006506 (0.02) ! GPI anchor biosynthetic process GO:0044464 (1.00) ! cell part; GO:0016021 (1.00) ! integral component of membrane; GO:0016020 (1.00) ! membrane; GO:0044424 (0.81) ! intracellular part; GO:0044444 (0.77) ! cytoplasmic part; GO:0005783 (0.75) ! endoplasmic reticulum; GO:0005886 (0.55) ! plasma membrane; GO:0005793 (0.24) ! endoplasmic reticulum-Golgi intermediate compartment; GO:0005794 (0.04) ! Golgi apparatus; GO:0005789 (0.03) ! endoplasmic reticulum membrane; GO:0005737 (0.03) ! cytoplasm GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 2 1702790-1710438 (17p13.3) Adrenal Gland: 8.64; Adipose - Subcutaneous: 7.79; Cells - Transformed fibroblasts: 7.48; Colon - Transverse: 7.12; Small Intestine - Terminal Ileum: 6.85; Nerve - Tibial: 5.68; Adipose - Visceral (Omentum): 5.52; Lung: 5.01; Bladder: 4.88; Cervix - Ectocervix: 4.74; Esophagus - Mucosa: 4.72; Fallopian Tube: 4.37; Vagina: 4.35; Breast - Mammary Tissue: 4.20; Cervix - Endocervix: 3.85; Ovary: 3.33; Artery - Tibial: 3.31; Minor Salivary Gland: 3.27; Artery - Coronary: 2.82; Esophagus - Muscularis: 2.69; Uterus: 2.66; Artery - Aorta: 2.66; Esophagus - Gastroesophageal Junction: 2.50; Colon - Sigmoid: 2.48; Liver: 2.46; Skin - Not Sun Exposed (Suprapubic): 2.17; Stomach: 2.07; Skin - Sun Exposed (Lower leg): 2.03; Thyroid: 2.01; Prostate: 1.76; Spleen: 1.09; Heart - Atrial Appendage: 1.05; Pituitary: 0.99; Kidney - Cortex: 0.82; Testis: 0.77; Heart - Left Ventricle: 0.57; Muscle - Skeletal: 0.56; Pancreas: 0.52; Brain - Spinal cord (cervical c-1): 0.39; Brain - Cortex: 0.26; Brain - Hypothalamus: 0.25; Brain - Anterior cingulate cortex (BA24): 0.25; Brain - Frontal Cortex (BA9): 0.24; Brain - Caudate (basal ganglia): 0.23; Brain - Hippocampus: 0.23; Brain - Substantia nigra: 0.22; Brain - Putamen (basal ganglia): 0.22; Brain - Amygdala: 0.22; Brain - Nucleus accumbens (basal ganglia): 0.20; Brain - Cerebellum: 0.20; Brain - Cerebellar Hemisphere: 0.14; Whole Blood: 0.09; Cells - EBV-transformed lymphocytes: 0.07; MAPTGLLVAGASFLAFRGLHWGLRRLPTPESAARDRWQWWNLCVSLAHSLLSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLADGADLLWNQTLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLRKLLLLSRQAPSLAFSVTSWASLATLALFRLVPLGWMSLWLFRQHHQVPLALVTLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHEKTRGTRTRRDNGPVTSNSSTLSLKD ZZEF1 Zinc finger ZZ-type and EF-hand domain-containing protein 1 ZZEF1_HUMAN (O43149-1) GO:0003824 (0.56) ! catalytic activity; GO:0016740 (0.53) ! transferase activity; GO:0004842 (0.32) ! ubiquitin-protein transferase activity; GO:0004672 (0.13) ! protein kinase activity; GO:0044877 (0.12) ! macromolecular complex binding; GO:0043169 (0.12) ! cation binding; GO:0009931 (0.12) ! calcium-dependent protein serine/threonine kinase activity; GO:0005516 (0.12) ! calmodulin binding; GO:0004683 (0.12) ! calmodulin-dependent protein kinase activity; GO:0046872 (0.11) ! metal ion binding; GO:0043130 (0.11) ! ubiquitin binding; GO:0005509 (0.10) ! calcium ion binding; GO:0042802 (0.09) ! identical protein binding; GO:0008092 (0.09) ! cytoskeletal protein binding; GO:0003700 (0.09) ! transcription factor activity, sequence-specific DNA binding; GO:0019899 (0.07) ! enzyme binding; GO:0005102 (0.07) ! receptor binding; GO:0003779 (0.07) ! actin binding; GO:0003712 (0.07) ! transcription cofactor activity; GO:0032403 (0.06) ! protein complex binding; GO:0004402 (0.06) ! histone acetyltransferase activity; GO:0003713 (0.06) ! transcription coactivator activity; GO:0003682 (0.06) ! chromatin binding; GO:0003676 (0.05) ! nucleic acid binding; GO:0051015 (0.04) ! actin filament binding; GO:0044212 (0.04) ! transcription regulatory region DNA binding; GO:0043565 (0.04) ! sequence-specific DNA binding; GO:0019901 (0.04) ! protein kinase binding; GO:0070011 (0.03) ! peptidase activity, acting on L-amino acid peptides; GO:0048306 (0.03) ! calcium-dependent protein binding; GO:0019904 (0.03) ! protein domain specific binding; GO:0017166 (0.03) ! vinculin binding; GO:0008307 (0.03) ! structural constituent of muscle; GO:0001078 (0.03) ! transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0000977 (0.03) ! RNA polymerase II regulatory region sequence-specific DNA binding; GO:0061630 (0.02) ! ubiquitin protein ligase activity; GO:0042803 (0.02) ! protein homodimerization activity; GO:0042169 (0.02) ! SH2 domain binding; GO:0008168 (0.02) ! methyltransferase activity; GO:0008134 (0.02) ! transcription factor binding; GO:0005215 (0.02) ! transporter activity; GO:0005178 (0.02) ! integrin binding; GO:0005161 (0.02) ! platelet-derived growth factor receptor binding; GO:0005080 (0.02) ! protein kinase C binding; GO:0004888 (0.02) ! transmembrane signaling receptor activity; GO:0004252 (0.02) ! serine-type endopeptidase activity; GO:1990226 (0.01) ! histone methyltransferase binding; GO:0098772 (0.01) ! molecular function regulator; GO:0050998 (0.01) ! nitric-oxide synthase binding; GO:0050699 (0.01) ! WW domain binding; GO:0044017 (0.01) ! histone acetyltransferase activity (H3-K27 specific); GO:0043993 (0.01) ! histone acetyltransferase activity (H3-K18 specific); GO:0043426 (0.01) ! MRF binding; GO:0042800 (0.01) ! histone methyltransferase activity (H3-K4 specific); GO:0042393 (0.01) ! histone binding; GO:0042166 (0.01) ! acetylcholine binding; GO:0033613 (0.01) ! activating transcription factor binding; GO:0032183 (0.01) ! SUMO binding; GO:0031625 (0.01) ! ubiquitin protein ligase binding; GO:0030165 (0.01) ! PDZ domain binding; GO:0017022 (0.01) ! myosin binding; GO:0015464 (0.01) ! acetylcholine receptor activity; GO:0008289 (0.01) ! lipid binding; GO:0008270 (0.01) ! zinc ion binding; GO:0008140 (0.01) ! cAMP response element binding protein binding; GO:0005160 (0.01) ! transforming growth factor beta receptor binding; GO:0005125 (0.01) ! cytokine activity; GO:0004889 (0.01) ! acetylcholine-activated cation-selective channel activity; GO:0003723 (0.01) ! RNA binding; GO:0003684 (0.01) ! damaged DNA binding; GO:0002162 (0.01) ! dystroglycan binding; GO:0001085 (0.01) ! RNA polymerase II transcription factor binding; GO:0001047 (0.01) ! core promoter binding GO:0009987 (0.84) ! cellular process; GO:0043170 (0.64) ! macromolecule metabolic process; GO:0044238 (0.63) ! primary metabolic process; GO:0044260 (0.61) ! cellular macromolecule metabolic process; GO:0019538 (0.61) ! protein metabolic process; GO:0065007 (0.50) ! biological regulation; GO:0006464 (0.50) ! cellular protein modification process; GO:0050789 (0.49) ! regulation of biological process; GO:0050794 (0.44) ! regulation of cellular process; GO:0032446 (0.36) ! protein modification by small protein conjugation; GO:0016567 (0.35) ! protein ubiquitination; GO:0044699 (0.31) ! single-organism process; GO:0048518 (0.24) ! positive regulation of biological process; GO:0042787 (0.23) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0048522 (0.21) ! positive regulation of cellular process; GO:0044763 (0.21) ! single-organism cellular process; GO:0007165 (0.21) ! signal transduction; GO:0006508 (0.21) ! proteolysis; GO:0032502 (0.20) ! developmental process; GO:0016043 (0.19) ! cellular component organization; GO:0044767 (0.18) ! single-organism developmental process; GO:0006511 (0.18) ! ubiquitin-dependent protein catabolic process; GO:0019222 (0.16) ! regulation of metabolic process; GO:0080090 (0.15) ! regulation of primary metabolic process; GO:0060255 (0.15) ! regulation of macromolecule metabolic process; GO:0048856 (0.15) ! anatomical structure development; GO:0031323 (0.15) ! regulation of cellular metabolic process; GO:0032501 (0.14) ! multicellular organismal process; GO:0018193 (0.14) ! peptidyl-amino acid modification; GO:0035556 (0.13) ! intracellular signal transduction; GO:0051171 (0.12) ! regulation of nitrogen compound metabolic process; GO:0009755 (0.12) ! hormone-mediated signaling pathway; GO:2000112 (0.11) ! regulation of cellular macromolecule biosynthetic process; GO:0051128 (0.11) ! regulation of cellular component organization; GO:0048869 (0.11) ! cellular developmental process; GO:0048583 (0.11) ! regulation of response to stimulus; GO:0046777 (0.11) ! protein autophosphorylation; GO:0043161 (0.11) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0032268 (0.11) ! regulation of cellular protein metabolic process; GO:0031325 (0.11) ! positive regulation of cellular metabolic process; GO:0023051 (0.11) ! regulation of signaling; GO:0019219 (0.11) ! regulation of nucleobase-containing compound metabolic process; GO:0018105 (0.11) ! peptidyl-serine phosphorylation; GO:0010646 (0.11) ! regulation of cell communication; GO:0010604 (0.11) ! positive regulation of macromolecule metabolic process; GO:0010468 (0.11) ! regulation of gene expression; GO:0009738 (0.11) ! abscisic acid-activated signaling pathway; GO:0044707 (0.10) ! single-multicellular organism process; GO:0031399 (0.10) ! regulation of protein modification process; GO:0006355 (0.10) ! regulation of transcription, DNA-templated; GO:0070979 (0.09) ! protein K11-linked ubiquitination; GO:0050896 (0.09) ! response to stimulus; GO:0043933 (0.09) ! macromolecular complex subunit organization; GO:0031401 (0.09) ! positive regulation of protein modification process; GO:0009966 (0.09) ! regulation of signal transduction; GO:0008054 (0.09) ! negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation; GO:0006357 (0.09) ! regulation of transcription from RNA polymerase II promoter; GO:0065008 (0.08) ! regulation of biological quality; GO:0051130 (0.08) ! positive regulation of cellular component organization; GO:0048513 (0.08) ! animal organ development; GO:0033043 (0.08) ! regulation of organelle organization; GO:1902531 (0.07) ! regulation of intracellular signal transduction; GO:0051239 (0.07) ! regulation of multicellular organismal process; GO:0016239 (0.07) ! positive regulation of macroautophagy; GO:0009653 (0.07) ! anatomical structure morphogenesis; GO:0007166 (0.07) ! cell surface receptor signaling pathway; GO:0006996 (0.07) ! organelle organization; GO:0006325 (0.07) ! chromatin organization; GO:1902589 (0.06) ! single-organism organelle organization; GO:0061061 (0.06) ! muscle structure development; GO:0051179 (0.06) ! localization; GO:0048519 (0.06) ! negative regulation of biological process; GO:0032879 (0.06) ! regulation of localization; GO:0065009 (0.05) ! regulation of molecular function; GO:0048584 (0.05) ! positive regulation of response to stimulus; GO:0048523 (0.05) ! negative regulation of cellular process; GO:0048468 (0.05) ! cell development; GO:0035065 (0.05) ! regulation of histone acetylation; GO:0031058 (0.05) ! positive regulation of histone modification; GO:0007010 (0.05) ! cytoskeleton organization; GO:0006928 (0.05) ! movement of cell or subcellular component; GO:0006810 (0.05) ! transport; GO:0003008 (0.05) ! system process; GO:0001932 (0.05) ! regulation of protein phosphorylation; GO:2000026 (0.04) ! regulation of multicellular organismal development; GO:1901576 (0.04) ! organic substance biosynthetic process; GO:0051726 (0.04) ! regulation of cell cycle; GO:0044271 (0.04) ! cellular nitrogen compound biosynthetic process; GO:0044093 (0.04) ! positive regulation of molecular function; GO:0043408 (0.04) ! regulation of MAPK cascade; GO:0035066 (0.04) ! positive regulation of histone acetylation; GO:0030154 (0.04) ! cell differentiation; GO:0022607 (0.04) ! cellular component assembly; GO:0022414 (0.04) ! reproductive process; GO:0009967 (0.04) ! positive regulation of signal transduction; GO:0009888 (0.04) ! tissue development; GO:0007525 (0.04) ! somatic muscle development; GO:0007517 (0.04) ! muscle organ development; GO:0007167 (0.04) ! enzyme linked receptor protein signaling pathway; GO:0007154 (0.04) ! cell communication; GO:0006950 (0.04) ! response to stress; GO:0006914 (0.04) ! autophagy; GO:0006338 (0.04) ! chromatin remodeling; GO:0001934 (0.04) ! positive regulation of protein phosphorylation; GO:0090287 (0.03) ! regulation of cellular response to growth factor stimulus; GO:0070372 (0.03) ! regulation of ERK1 and ERK2 cascade; GO:0051962 (0.03) ! positive regulation of nervous system development; GO:0051716 (0.03) ! cellular response to stimulus; GO:0051270 (0.03) ! regulation of cellular component movement; GO:0051049 (0.03) ! regulation of transport; GO:0050808 (0.03) ! synapse organization; GO:0050790 (0.03) ! regulation of catalytic activity; GO:0048747 (0.03) ! muscle fiber development; GO:0045935 (0.03) ! positive regulation of nucleobase-containing compound metabolic process; GO:0045214 (0.03) ! sarcomere organization; GO:0044702 (0.03) ! single organism reproductive process; GO:0042592 (0.03) ! homeostatic process; GO:0042127 (0.03) ! regulation of cell proliferation; GO:0040017 (0.03) ! positive regulation of locomotion; GO:0032989 (0.03) ! cellular component morphogenesis; GO:0031328 (0.03) ! positive regulation of cellular biosynthetic process; GO:0031324 (0.03) ! negative regulation of cellular metabolic process; GO:0022402 (0.03) ! cell cycle process; GO:0018205 (0.03) ! peptidyl-lysine modification; GO:0016570 (0.03) ! histone modification; GO:0016477 (0.03) ! cell migration; GO:0016236 (0.03) ! macroautophagy; GO:0014904 (0.03) ! myotube cell development; GO:0010975 (0.03) ! regulation of neuron projection development; GO:0010605 (0.03) ! negative regulation of macromolecule metabolic process; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0007519 (0.03) ! skeletal muscle tissue development; GO:0007389 (0.03) ! pattern specification process; GO:0007169 (0.03) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007088 (0.03) ! regulation of mitotic nuclear division; GO:0006941 (0.03) ! striated muscle contraction; GO:0006937 (0.03) ! regulation of muscle contraction; GO:0006461 (0.03) ! protein complex assembly; GO:0006366 (0.03) ! transcription from RNA polymerase II promoter; GO:0003006 (0.03) ! developmental process involved in reproduction; GO:2000649 (0.02) ! regulation of sodium ion transmembrane transporter activity; GO:1903047 (0.02) ! mitotic cell cycle process; GO:0090092 (0.02) ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0070374 (0.02) ! positive regulation of ERK1 and ERK2 cascade; GO:0061053 (0.02) ! somite development; GO:0060341 (0.02) ! regulation of cellular localization; GO:0060048 (0.02) ! cardiac muscle contraction; GO:0051641 (0.02) ! cellular localization; GO:0050877 (0.02) ! neurological system process; GO:0048741 (0.02) ! skeletal muscle fiber development; GO:0048646 (0.02) ! anatomical structure formation involved in morphogenesis; GO:0048608 (0.02) ! reproductive structure development; GO:0048008 (0.02) ! platelet-derived growth factor receptor signaling pathway; GO:0046716 (0.02) ! muscle cell cellular homeostasis; GO:0045944 (0.02) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045926 (0.02) ! negative regulation of growth; GO:0044765 (0.02) ! single-organism transport; GO:0043406 (0.02) ! positive regulation of MAP kinase activity; GO:0043122 (0.02) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0042981 (0.02) ! regulation of apoptotic process; GO:0033554 (0.02) ! cellular response to stress; GO:0032259 (0.02) ! methylation; GO:0031954 (0.02) ! positive regulation of protein autophosphorylation; GO:0030947 (0.02) ! regulation of vascular endothelial growth factor receptor signaling pathway; GO:0030335 (0.02) ! positive regulation of cell migration; GO:0030030 (0.02) ! cell projection organization; GO:0016573 (0.02) ! histone acetylation; GO:0016203 (0.02) ! muscle attachment; GO:0014068 (0.02) ! positive regulation of phosphatidylinositol 3-kinase signaling; GO:0010976 (0.02) ! positive regulation of neuron projection development; GO:0010769 (0.02) ! regulation of cell morphogenesis involved in differentiation; GO:0010629 (0.02) ! negative regulation of gene expression; GO:0010033 (0.02) ! response to organic substance; GO:0008586 (0.02) ! imaginal disc-derived wing vein morphogenesis; GO:0008284 (0.02) ! positive regulation of cell proliferation; GO:0008104 (0.02) ! protein localization; GO:0008038 (0.02) ! neuron recognition; GO:0007626 (0.02) ! locomotory behavior; GO:0007596 (0.02) ! blood coagulation; GO:0007411 (0.02) ! axon guidance; GO:0007268 (0.02) ! chemical synaptic transmission; GO:0007219 (0.02) ! Notch signaling pathway; GO:0006897 (0.02) ! endocytosis; GO:0003009 (0.02) ! skeletal muscle contraction; GO:0003002 (0.02) ! regionalization; GO:0001954 (0.02) ! positive regulation of cell-matrix adhesion; GO:0001755 (0.02) ! neural crest cell migration; GO:0001570 (0.02) ! vasculogenesis; GO:0000904 (0.02) ! cell morphogenesis involved in differentiation; GO:0000226 (0.02) ! microtubule cytoskeleton organization; GO:2000651 (0.01) ! positive regulation of sodium ion transmembrane transporter activity; GO:1902083 (0.01) ! negative regulation of peptidyl-cysteine S-nitrosylation; GO:1901700 (0.01) ! response to oxygen-containing compound; GO:1901385 (0.01) ! regulation of voltage-gated calcium channel activity; GO:0098779 (0.01) ! mitophagy in response to mitochondrial depolarization; GO:0086001 (0.01) ! cardiac muscle cell action potential; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0071705 (0.01) ! nitrogen compound transport; GO:0071310 (0.01) ! cellular response to organic substance; GO:0061635 (0.01) ! regulation of protein complex stability; GO:0060560 (0.01) ! developmental growth involved in morphogenesis; GO:0060395 (0.01) ! SMAD protein signal transduction; GO:0060314 (0.01) ! regulation of ryanodine-sensitive calcium-release channel activity; GO:0051704 (0.01) ! multi-organism process; GO:0051568 (0.01) ! histone H3-K4 methylation; GO:0051260 (0.01) ! protein homooligomerization; GO:0051129 (0.01) ! negative regulation of cellular component organization; GO:0050775 (0.01) ! positive regulation of dendrite morphogenesis; GO:0048749 (0.01) ! compound eye development; GO:0048729 (0.01) ! tissue morphogenesis; GO:0048640 (0.01) ! negative regulation of developmental growth; GO:0048598 (0.01) ! embryonic morphogenesis; GO:0048172 (0.01) ! regulation of short-term neuronal synaptic plasticity; GO:0048066 (0.01) ! developmental pigmentation; GO:0046928 (0.01) ! regulation of neurotransmitter secretion; GO:0046907 (0.01) ! intracellular transport; GO:0045665 (0.01) ! negative regulation of neuron differentiation; GO:0045475 (0.01) ! locomotor rhythm; GO:0045466 (0.01) ! R7 cell differentiation; GO:0044087 (0.01) ! regulation of cellular component biogenesis; GO:0043983 (0.01) ! histone H4-K12 acetylation; GO:0043982 (0.01) ! histone H4-K8 acetylation; GO:0043974 (0.01) ! histone H3-K27 acetylation; GO:0043971 (0.01) ! histone H3-K18 acetylation; GO:0043903 (0.01) ! regulation of symbiosis, encompassing mutualism through parasitism; GO:0043901 (0.01) ! negative regulation of multi-organism process; GO:0043623 (0.01) ! cellular protein complex assembly; GO:0043409 (0.01) ! negative regulation of MAPK cascade; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043043 (0.01) ! peptide biosynthetic process; GO:0042593 (0.01) ! glucose homeostasis; GO:0042068 (0.01) ! regulation of pteridine metabolic process; GO:0042060 (0.01) ! wound healing; GO:0040040 (0.01) ! thermosensory behavior; GO:0035994 (0.01) ! response to muscle stretch; GO:0034644 (0.01) ! cellular response to UV; GO:0034613 (0.01) ! cellular protein localization; GO:0033993 (0.01) ! response to lipid; GO:0033137 (0.01) ! negative regulation of peptidyl-serine phosphorylation; GO:0032922 (0.01) ! circadian regulation of gene expression; GO:0032102 (0.01) ! negative regulation of response to external stimulus; GO:0031347 (0.01) ! regulation of defense response; GO:0031290 (0.01) ! retinal ganglion cell axon guidance; GO:0031062 (0.01) ! positive regulation of histone methylation; GO:0030855 (0.01) ! epithelial cell differentiation; GO:0030707 (0.01) ! ovarian follicle cell development; GO:0030522 (0.01) ! intracellular receptor signaling pathway; GO:0030516 (0.01) ! regulation of axon extension; GO:0030509 (0.01) ! BMP signaling pathway; GO:0030308 (0.01) ! negative regulation of cell growth; GO:0030097 (0.01) ! hemopoiesis; GO:0030010 (0.01) ! establishment of cell polarity; GO:0022008 (0.01) ! neurogenesis; GO:0021986 (0.01) ! habenula development; GO:0019233 (0.01) ! sensory perception of pain; GO:0018076 (0.01) ! N-terminal peptidyl-lysine acetylation; GO:0016485 (0.01) ! protein processing; GO:0016198 (0.01) ! axon choice point recognition; GO:0016055 (0.01) ! Wnt signaling pathway; GO:0016049 (0.01) ! cell growth; GO:0015031 (0.01) ! protein transport; GO:0014809 (0.01) ! regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0010906 (0.01) ! regulation of glucose metabolic process; GO:0010881 (0.01) ! regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; GO:0010862 (0.01) ! positive regulation of pathway-restricted SMAD protein phosphorylation; GO:0009791 (0.01) ! post-embryonic development; GO:0009725 (0.01) ! response to hormone; GO:0008347 (0.01) ! glial cell migration; GO:0008283 (0.01) ! cell proliferation; GO:0008045 (0.01) ! motor neuron axon guidance; GO:0007528 (0.01) ! neuromuscular junction development; GO:0007527 (0.01) ! adult somatic muscle development; GO:0007507 (0.01) ! heart development; GO:0007474 (0.01) ! imaginal disc-derived wing vein specification; GO:0007464 (0.01) ! R3/R4 cell fate commitment; GO:0007417 (0.01) ! central nervous system development; GO:0007416 (0.01) ! synapse assembly; GO:0007413 (0.01) ! axonal fasciculation; GO:0007409 (0.01) ! axonogenesis; GO:0007283 (0.01) ! spermatogenesis; GO:0007275 (0.01) ! multicellular organism development; GO:0007274 (0.01) ! neuromuscular synaptic transmission; GO:0007271 (0.01) ! synaptic transmission, cholinergic; GO:0007269 (0.01) ! neurotransmitter secretion; GO:0007224 (0.01) ! smoothened signaling pathway; GO:0007155 (0.01) ! cell adhesion; GO:0007030 (0.01) ! Golgi organization; GO:0006915 (0.01) ! apoptotic process; GO:0006281 (0.01) ! DNA repair; GO:0006006 (0.01) ! glucose metabolic process; GO:0003231 (0.01) ! cardiac ventricle development; GO:0002040 (0.01) ! sprouting angiogenesis; GO:0002027 (0.01) ! regulation of heart rate; GO:0001890 (0.01) ! placenta development; GO:0001867 (0.01) ! complement activation, lectin pathway; GO:0001837 (0.01) ! epithelial to mesenchymal transition; GO:0001745 (0.01) ! compound eye morphogenesis; GO:0000281 (0.01) ! mitotic cytokinesis; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter; GO:0000076 (0.01) ! DNA replication checkpoint GO:0044464 (0.91) ! cell part; GO:0044424 (0.83) ! intracellular part; GO:0043226 (0.65) ! organelle; GO:0043229 (0.62) ! intracellular organelle; GO:0043227 (0.62) ! membrane-bounded organelle; GO:0043231 (0.58) ! intracellular membrane-bounded organelle; GO:0005634 (0.47) ! nucleus; GO:0005737 (0.46) ! cytoplasm; GO:0032991 (0.28) ! macromolecular complex; GO:0043234 (0.27) ! protein complex; GO:0044422 (0.24) ! organelle part; GO:0044446 (0.23) ! intracellular organelle part; GO:0044444 (0.21) ! cytoplasmic part; GO:0016020 (0.19) ! membrane; GO:0044428 (0.17) ! nuclear part; GO:1990234 (0.15) ! transferase complex; GO:0005886 (0.14) ! plasma membrane; GO:0044425 (0.12) ! membrane part; GO:0031461 (0.12) ! cullin-RING ubiquitin ligase complex; GO:0044459 (0.11) ! plasma membrane part; GO:0005773 (0.10) ! vacuole; GO:0005680 (0.10) ! anaphase-promoting complex; GO:0044421 (0.09) ! extracellular region part; GO:0005776 (0.09) ! autophagosome; GO:0098797 (0.08) ! plasma membrane protein complex; GO:0043232 (0.08) ! intracellular non-membrane-bounded organelle; GO:0016235 (0.07) ! aggresome; GO:0016010 (0.07) ! dystrophin-associated glycoprotein complex; GO:0045202 (0.06) ! synapse; GO:0044463 (0.05) ! cell projection part; GO:0044430 (0.05) ! cytoskeletal part; GO:0042383 (0.05) ! sarcolemma; GO:0031988 (0.05) ! membrane-bounded vesicle; GO:0005654 (0.05) ! nucleoplasm; GO:0005615 (0.05) ! extracellular space; GO:0097458 (0.04) ! neuron part; GO:0070062 (0.04) ! extracellular exosome; GO:0044451 (0.04) ! nucleoplasm part; GO:0042995 (0.04) ! cell projection; GO:0044449 (0.03) ! contractile fiber part; GO:0031594 (0.03) ! neuromuscular junction; GO:0031253 (0.03) ! cell projection membrane; GO:0005856 (0.03) ! cytoskeleton; GO:0005829 (0.03) ! cytosol; GO:0070938 (0.02) ! contractile ring; GO:0048471 (0.02) ! perinuclear region of cytoplasm; GO:0043235 (0.02) ! receptor complex; GO:0043005 (0.02) ! neuron projection; GO:0035097 (0.02) ! histone methyltransferase complex; GO:0031527 (0.02) ! filopodium membrane; GO:0030426 (0.02) ! growth cone; GO:0030175 (0.02) ! filopodium; GO:0030054 (0.02) ! cell junction; GO:0016021 (0.02) ! integral component of membrane; GO:0016014 (0.02) ! dystrobrevin complex; GO:0009986 (0.02) ! cell surface; GO:0005861 (0.02) ! troponin complex; GO:0005813 (0.02) ! centrosome; GO:0005794 (0.02) ! Golgi apparatus; GO:0005576 (0.02) ! extracellular region; GO:0000407 (0.02) ! pre-autophagosomal structure; GO:0000123 (0.02) ! histone acetyltransferase complex; GO:1990393 (0.01) ! 3M complex; GO:0098805 (0.01) ! whole membrane; GO:0098588 (0.01) ! bounding membrane of organelle; GO:0070461 (0.01) ! SAGA-type complex; GO:0045121 (0.01) ! membrane raft; GO:0044754 (0.01) ! autolysosome; GO:0044753 (0.01) ! amphisome; GO:0044666 (0.01) ! MLL3/4 complex; GO:0044456 (0.01) ! synapse part; GO:0044306 (0.01) ! neuron projection terminus; GO:0043034 (0.01) ! costamere; GO:0031467 (0.01) ! Cul7-RING ubiquitin ligase complex; GO:0031012 (0.01) ! extracellular matrix; GO:0030864 (0.01) ! cortical actin cytoskeleton; GO:0030659 (0.01) ! cytoplasmic vesicle membrane; GO:0030424 (0.01) ! axon; GO:0030055 (0.01) ! cell-substrate junction; GO:0030018 (0.01) ! Z disc; GO:0019898 (0.01) ! extrinsic component of membrane; GO:0016605 (0.01) ! PML body; GO:0016023 (0.01) ! cytoplasmic, membrane-bounded vesicle; GO:0015629 (0.01) ! actin cytoskeleton; GO:0009506 (0.01) ! plasmodesma; GO:0005938 (0.01) ! cell cortex; GO:0005892 (0.01) ! acetylcholine-gated channel complex; GO:0005887 (0.01) ! integral component of plasma membrane; GO:0005768 (0.01) ! endosome; GO:0005700 (0.01) ! polytene chromosome; GO:0005667 (0.01) ! transcription factor complex; GO:0000932 (0.01) ! cytoplasmic mRNA processing body; GO:0000790 (0.01) ! nuclear chromatin GO:0008270 ! zinc ion binding; GO:0005509 ! calcium ion binding; GO:0046872 ! metal ion binding 5 GO:0005509 ! calcium ion binding; GO:0008270 ! zinc ion binding 4004445-4143020 (17p13.2) Small Intestine - Terminal Ileum: 43.22; Esophagus - Muscularis: 31.11; Colon - Transverse: 28.12; Esophagus - Gastroesophageal Junction: 27.03; Spleen: 27.02; Thyroid: 25.73; Uterus: 25.32; Bladder: 25.27; Brain - Cerebellum: 25.15; Artery - Tibial: 24.35; Ovary: 23.78; Lung: 23.66; Brain - Cerebellar Hemisphere: 23.14; Pituitary: 23.03; Colon - Sigmoid: 22.73; Artery - Aorta: 22.63; Fallopian Tube: 22.41; Nerve - Tibial: 22.25; Prostate: 21.86; Skin - Sun Exposed (Lower leg): 21.84; Cervix - Endocervix: 21.42; Testis: 20.41; Cells - EBV-transformed lymphocytes: 20.20; Artery - Coronary: 20.08; Cervix - Ectocervix: 20.04; Adipose - Subcutaneous: 19.91; Skin - Not Sun Exposed (Suprapubic): 19.85; Breast - Mammary Tissue: 19.05; Muscle - Skeletal: 17.50; Esophagus - Mucosa: 17.39; Vagina: 17.06; Stomach: 16.68; Adrenal Gland: 15.86; Minor Salivary Gland: 15.42; Cells - Transformed fibroblasts: 15.19; Adipose - Visceral (Omentum): 14.74; Pancreas: 10.72; Whole Blood: 10.16; Brain - Cortex: 9.82; Heart - Atrial Appendage: 9.15; Brain - Spinal cord (cervical c-1): 8.98; Brain - Frontal Cortex (BA9): 8.79; Kidney - Cortex: 8.35; Brain - Hypothalamus: 7.76; Heart - Left Ventricle: 7.27; Brain - Nucleus accumbens (basal ganglia): 6.99; Brain - Substantia nigra: 6.88; Brain - Caudate (basal ganglia): 6.35; Liver: 6.34; Brain - Hippocampus: 6.33; Brain - Anterior cingulate cortex (BA24): 6.28; Brain - Putamen (basal ganglia): 5.75; Brain - Amygdala: 5.46; MGNAPSHSSEDEAAAAGGEGWGPHQDWAAVSGTTPGPGVAAPALPPAAALLEPARLREAAAALLPTPPCESLVSRHRGALFRWLEERLGRGEESVTLEQFRELLEARGAGCSSEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHIIRQLQACSLVPGFTDIFSESKEGLDIHSSMILRFLHRNRLSSAVMPYPMLEHCNNMCTMRSSVLKESLDQLVQKEKESPGDLTRSPEMDKLKSVAKCYAYIETSSNSADIDKMTNGETSSYWQSDGSACSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRNASDLQEVRDVHIPSNVTGYVTLLENANVSQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLHNTQKALRHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSVAKVMSSLCTITDHLDTQYDASSLILSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSSSDKFCAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLTISGYLRPARAEAEQSVTCAHCRKDTEESVCGATLLLRTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECVSAQTLLLQLLQSCFSVLQGDVLAASEEEKAPIQSPKGVEAAKELYTHLCDVVDKVDGDSVPMEILKQEVRNTLLNGAAIFFPNRQTRRNHLFTMMNVTEQEHKQSLQLTFRSLCTYFSDKDPGGLLLLPEKNDLAKMNISEVLAVMDTLVSVAARECELLMLSGAPGEVGSVLFSLFWSVQGSLLSWCYLQLKSTDSGAKDLAVDLIEKYVGQFLASMRAILESLFSQYSGKTIVERLCNSVFSMAARQLVIFLLDFCTLDIPHCVLLREFSVLTELLKKLCSGPEGGLRKLDVETWQQEQPVVLHTWTKESAHNYENNCHEVSVFVSPGATYFEVEFDDRCETEKRYDYLEFTDARGRKTRYDTKVGTDKWPKKVTFKAGPRLQFLFHSDSSHNEWGYKFTVTACGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVRQLGSNMVVPQAKMALVLSSPLWKPVFRHQVCPELELEASWPTHPHRNSKEVKNIPDDPCRHFLLDFAQSEPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVNSGGKIALSEEFAQVYSLADGIRIWMLEMKQKSLMSLGNEAEEKHSSEATEVNPESLAKECIEKSLLLLKFLPTGISSKESCEKLETADETSHLQPLNKRQRTSSVVEEHFQASVSPTEAAPPATGDQSPGLGTQPKLPSSSGLPAADVSPATAEEPLSPSTPTRRPPFTRGRLRLLSFRSMEEARLVPTVKEKYPVLKDVMDFIKDQSLSHRSVVKVLSLRKAQAQSILEVLKITQHCAESLGQPHCFHPPFILFLLELLTCQKDFTNYFGHLEGCGADLHKEIRDTYYQLVLFLVKAVKGFSSLNDRSLLPALSCVQTALLHLLDMGWEPNDLAFFVDIQLPDLLMKMSQENISVHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSWLLFAALALYSAHLASAEDVDGEKLDPQTRSSATTLRSQCMQLVGDCLMKAHQGKGLKALALLGVLPDGDSSLEDQALPVTVPTGASEEQLEKKAVQGAELSEAGNGKRAVHEEIRPVDFKQRNKADKGVSLSKDPSCQTQISDSPADASPPTGLPDAEDSEVSSQKPIEEKAVTPSPEQVFAECSQKRILGLLAAMLPPLKSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLLPAEVDAAVIKVLSAKHNLFAAGDSSIVPDGWKTTHLLFSLGAVCLDSRVGLDWACSMAEILRSLNSAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGGGQECGDSRAQLSQYSQHFAFIASHLLQSSMDSHCPEAVEATWVLSLALKGLYKTLKAHGFEEIRATFLQTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINALAEHGDLELDERGDREEEVERPVSSPGDPEQKKLDPLEGLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDYFFLEVQKRFDGDELTTDERIRSLAQRWQPSKSLRLEEQSAKAVDTDMIILPCLSRPARCDQATAESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSKRAVRDYLFRVNEATAVLYARHVLASLLAEWPSHVPVSEDILELSGPAHMTYILDMFMQLEEKHEWEKILQKVLQGCREDMLGTMALAACQFMEEPGMEVQVRESKHPYNNNTNFEDKVHIPGAIYLSIKFDSQCNTEEGCDELAMSSSSDFQQDRHSFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPHLPLAKIWEWLVGVACRQTGHQRLKAIHLLLRIVRCCGHSDLCDLALLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALTELFFVTENRAQELGVLQDYLLALTTDDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC SMTNL2 Smoothelin-like protein 2 SMTL2_HUMAN (Q2TAL5-1) GO:0008092 (0.77) ! cytoskeletal protein binding; GO:0003779 (0.42) ! actin binding; GO:1901363 (0.40) ! heterocyclic compound binding; GO:0097159 (0.40) ! organic cyclic compound binding; GO:0050660 (0.37) ! flavin adenine dinucleotide binding; GO:0046983 (0.30) ! protein dimerization activity; GO:0042802 (0.30) ! identical protein binding; GO:0042803 (0.29) ! protein homodimerization activity; GO:0003824 (0.29) ! catalytic activity; GO:0019899 (0.28) ! enzyme binding; GO:0017166 (0.28) ! vinculin binding; GO:0051393 (0.25) ! alpha-actinin binding; GO:0019904 (0.22) ! protein domain specific binding; GO:0017016 (0.22) ! Ras GTPase binding; GO:0016705 (0.22) ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; GO:0043167 (0.21) ! ion binding; GO:0046872 (0.20) ! metal ion binding; GO:0046914 (0.19) ! transition metal ion binding; GO:0044877 (0.15) ! macromolecular complex binding; GO:0032403 (0.14) ! protein complex binding; GO:0051015 (0.10) ! actin filament binding; GO:0008017 (0.10) ! microtubule binding; GO:0005198 (0.08) ! structural molecule activity; GO:0050839 (0.06) ! cell adhesion molecule binding; GO:0005215 (0.06) ! transporter activity; GO:0016740 (0.05) ! transferase activity; GO:0005102 (0.05) ! receptor binding; GO:0003676 (0.05) ! nucleic acid binding; GO:0098772 (0.04) ! molecular function regulator; GO:0071949 (0.04) ! FAD binding; GO:0044822 (0.04) ! poly(A) RNA binding; GO:0030506 (0.04) ! ankyrin binding; GO:0019901 (0.04) ! protein kinase binding; GO:0016772 (0.04) ! transferase activity, transferring phosphorus-containing groups; GO:0016709 (0.04) ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; GO:0008324 (0.04) ! cation transmembrane transporter activity; GO:0005178 (0.04) ! integrin binding; GO:0046873 (0.03) ! metal ion transmembrane transporter activity; GO:0030507 (0.03) ! spectrin binding; GO:0030374 (0.03) ! ligand-dependent nuclear receptor transcription coactivator activity; GO:0022836 (0.03) ! gated channel activity; GO:0016887 (0.03) ! ATPase activity; GO:0008307 (0.03) ! structural constituent of muscle; GO:0005261 (0.03) ! cation channel activity; GO:0005200 (0.03) ! structural constituent of cytoskeleton; GO:0098641 (0.02) ! cadherin binding involved in cell-cell adhesion; GO:0097367 (0.02) ! carbohydrate derivative binding; GO:0097110 (0.02) ! scaffold protein binding; GO:0044325 (0.02) ! ion channel binding; GO:0030674 (0.02) ! protein binding, bridging; GO:0019902 (0.02) ! phosphatase binding; GO:0017137 (0.02) ! Rab GTPase binding; GO:0008332 (0.02) ! low voltage-gated calcium channel activity; GO:0005543 (0.02) ! phospholipid binding; GO:0005487 (0.02) ! nucleocytoplasmic transporter activity; GO:0005088 (0.02) ! Ras guanyl-nucleotide exchange factor activity; GO:0004871 (0.02) ! signal transducer activity; GO:0004672 (0.02) ! protein kinase activity; GO:0003774 (0.02) ! motor activity; GO:0001055 (0.02) ! RNA polymerase II activity; GO:0070300 (0.01) ! phosphatidic acid binding; GO:0070080 (0.01) ! titin Z domain binding; GO:0051373 (0.01) ! FATZ binding; GO:0051219 (0.01) ! phosphoprotein binding; GO:0051010 (0.01) ! microtubule plus-end binding; GO:0050998 (0.01) ! nitric-oxide synthase binding; GO:0048365 (0.01) ! Rac GTPase binding; GO:0047485 (0.01) ! protein N-terminus binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0045505 (0.01) ! dynein intermediate chain binding; GO:0043914 (0.01) ! NADPH:sulfur oxidoreductase activity; GO:0043621 (0.01) ! protein self-association; GO:0043495 (0.01) ! protein anchor; GO:0042974 (0.01) ! retinoic acid receptor binding; GO:0034452 (0.01) ! dynactin binding; GO:0032029 (0.01) ! myosin tail binding; GO:0031490 (0.01) ! chromatin DNA binding; GO:0031432 (0.01) ! titin binding; GO:0031005 (0.01) ! filamin binding; GO:0030274 (0.01) ! LIM domain binding; GO:0019894 (0.01) ! kinesin binding; GO:0017124 (0.01) ! SH3 domain binding; GO:0017020 (0.01) ! myosin phosphatase regulator activity; GO:0008331 (0.01) ! high voltage-gated calcium channel activity; GO:0008157 (0.01) ! protein phosphatase 1 binding; GO:0008093 (0.01) ! cytoskeletal adaptor activity; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005546 (0.01) ! phosphatidylinositol-4,5-bisphosphate binding; GO:0005521 (0.01) ! lamin binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005201 (0.01) ! extracellular matrix structural constituent; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0004888 (0.01) ! transmembrane signaling receptor activity; GO:0004864 (0.01) ! protein phosphatase inhibitor activity; GO:0004702 (0.01) ! receptor signaling protein serine/threonine kinase activity; GO:0003777 (0.01) ! microtubule motor activity; GO:0003729 (0.01) ! mRNA binding; GO:0003725 (0.01) ! double-stranded RNA binding; GO:0002162 (0.01) ! dystroglycan binding; GO:0001882 (0.01) ! nucleoside binding; GO:0000977 (0.01) ! RNA polymerase II regulatory region sequence-specific DNA binding GO:0044699 (0.86) ! single-organism process; GO:0009987 (0.82) ! cellular process; GO:0044763 (0.76) ! single-organism cellular process; GO:0016043 (0.70) ! cellular component organization; GO:0032502 (0.69) ! developmental process; GO:0044767 (0.63) ! single-organism developmental process; GO:0048856 (0.59) ! anatomical structure development; GO:0065007 (0.51) ! biological regulation; GO:0050789 (0.47) ! regulation of biological process; GO:0006996 (0.47) ! organelle organization; GO:0007010 (0.45) ! cytoskeleton organization; GO:0050794 (0.44) ! regulation of cellular process; GO:1902589 (0.42) ! single-organism organelle organization; GO:0048869 (0.41) ! cellular developmental process; GO:0030029 (0.41) ! actin filament-based process; GO:0030036 (0.39) ! actin cytoskeleton organization; GO:0048519 (0.32) ! negative regulation of biological process; GO:0031032 (0.31) ! actomyosin structure organization; GO:0048523 (0.30) ! negative regulation of cellular process; GO:0048468 (0.30) ! cell development; GO:0045214 (0.28) ! sarcomere organization; GO:0008152 (0.28) ! metabolic process; GO:0080090 (0.26) ! regulation of primary metabolic process; GO:0060255 (0.26) ! regulation of macromolecule metabolic process; GO:0044237 (0.26) ! cellular metabolic process; GO:0032501 (0.26) ! multicellular organismal process; GO:0031323 (0.26) ! regulation of cellular metabolic process; GO:0007015 (0.26) ! actin filament organization; GO:0048747 (0.25) ! muscle fiber development; GO:0043933 (0.25) ! macromolecular complex subunit organization; GO:0014904 (0.25) ! myotube cell development; GO:0071822 (0.24) ! protein complex subunit organization; GO:0048741 (0.24) ! skeletal muscle fiber development; GO:0065009 (0.23) ! regulation of molecular function; GO:0051179 (0.23) ! localization; GO:0048518 (0.23) ! positive regulation of biological process; GO:0044710 (0.23) ! single-organism metabolic process; GO:0065008 (0.22) ! regulation of biological quality; GO:0051261 (0.22) ! protein depolymerization; GO:0031324 (0.22) ! negative regulation of cellular metabolic process; GO:0010605 (0.22) ! negative regulation of macromolecule metabolic process; GO:0009653 (0.22) ! anatomical structure morphogenesis; GO:0008154 (0.22) ! actin polymerization or depolymerization; GO:0001932 (0.22) ! regulation of protein phosphorylation; GO:0055114 (0.21) ! oxidation-reduction process; GO:0051336 (0.21) ! regulation of hydrolase activity; GO:0051248 (0.21) ! negative regulation of protein metabolic process; GO:0044707 (0.21) ! single-multicellular organism process; GO:0042981 (0.21) ! regulation of apoptotic process; GO:0006790 (0.21) ! sulfur compound metabolic process; GO:0051234 (0.20) ! establishment of localization; GO:0044092 (0.20) ! negative regulation of molecular function; GO:0042326 (0.20) ! negative regulation of phosphorylation; GO:0031400 (0.20) ! negative regulation of protein modification process; GO:2000117 (0.19) ! negative regulation of cysteine-type endopeptidase activity; GO:0043281 (0.19) ! regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0043069 (0.19) ! negative regulation of programmed cell death; GO:0006810 (0.19) ! transport; GO:0048522 (0.18) ! positive regulation of cellular process; GO:0048513 (0.17) ! animal organ development; GO:0051239 (0.16) ! regulation of multicellular organismal process; GO:0051641 (0.14) ! cellular localization; GO:0051128 (0.14) ! regulation of cellular component organization; GO:0051240 (0.12) ! positive regulation of multicellular organismal process; GO:0030030 (0.12) ! cell projection organization; GO:0022607 (0.12) ! cellular component assembly; GO:0009888 (0.12) ! tissue development; GO:0051649 (0.11) ! establishment of localization in cell; GO:0050896 (0.11) ! response to stimulus; GO:0050793 (0.11) ! regulation of developmental process; GO:0044700 (0.11) ! single organism signaling; GO:0051130 (0.10) ! positive regulation of cellular component organization; GO:0046907 (0.10) ! intracellular transport; GO:0033043 (0.10) ! regulation of organelle organization; GO:0032989 (0.10) ! cellular component morphogenesis; GO:0032879 (0.10) ! regulation of localization; GO:0007267 (0.10) ! cell-cell signaling; GO:0007017 (0.10) ! microtubule-based process; GO:1902578 (0.09) ! single-organism localization; GO:0061061 (0.09) ! muscle structure development; GO:0051094 (0.09) ! positive regulation of developmental process; GO:0048646 (0.09) ! anatomical structure formation involved in morphogenesis; GO:0045927 (0.09) ! positive regulation of growth; GO:0010639 (0.09) ! negative regulation of organelle organization; GO:0009886 (0.09) ! post-embryonic morphogenesis; GO:0000226 (0.09) ! microtubule cytoskeleton organization; GO:2000026 (0.08) ! regulation of multicellular organismal development; GO:0060284 (0.08) ! regulation of cell development; GO:0051493 (0.08) ! regulation of cytoskeleton organization; GO:0048812 (0.08) ! neuron projection morphogenesis; GO:0048731 (0.08) ! system development; GO:0048639 (0.08) ! positive regulation of developmental growth; GO:0044765 (0.08) ! single-organism transport; GO:0044087 (0.08) ! regulation of cellular component biogenesis; GO:0032886 (0.08) ! regulation of microtubule-based process; GO:0023051 (0.08) ! regulation of signaling; GO:0022414 (0.08) ! reproductive process; GO:0016192 (0.08) ! vesicle-mediated transport; GO:0010646 (0.08) ! regulation of cell communication; GO:0008104 (0.08) ! protein localization; GO:0007165 (0.08) ! signal transduction; GO:0006928 (0.08) ! movement of cell or subcellular component; GO:0071704 (0.07) ! organic substance metabolic process; GO:0051049 (0.07) ! regulation of transport; GO:0044802 (0.07) ! single-organism membrane organization; GO:0044702 (0.07) ! single organism reproductive process; GO:0035239 (0.07) ! tube morphogenesis; GO:0034613 (0.07) ! cellular protein localization; GO:0016203 (0.07) ! muscle attachment; GO:0010976 (0.07) ! positive regulation of neuron projection development; GO:0010769 (0.07) ! regulation of cell morphogenesis involved in differentiation; GO:0007475 (0.07) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.07) ! open tracheal system development; GO:0007423 (0.07) ! sensory organ development; GO:0007409 (0.07) ! axonogenesis; GO:0007275 (0.07) ! multicellular organism development; GO:0007026 (0.07) ! negative regulation of microtubule depolymerization; GO:1903047 (0.06) ! mitotic cell cycle process; GO:1902580 (0.06) ! single-organism cellular localization; GO:0090066 (0.06) ! regulation of anatomical structure size; GO:0051491 (0.06) ! positive regulation of filopodium assembly; GO:0048813 (0.06) ! dendrite morphogenesis; GO:0045773 (0.06) ! positive regulation of axon extension; GO:0045184 (0.06) ! establishment of protein localization; GO:0044260 (0.06) ! cellular macromolecule metabolic process; GO:0044238 (0.06) ! primary metabolic process; GO:0044057 (0.06) ! regulation of system process; GO:0035149 (0.06) ! lumen formation, open tracheal system; GO:0035147 (0.06) ! branch fusion, open tracheal system; GO:0030716 (0.06) ! oocyte fate determination; GO:0019219 (0.06) ! regulation of nucleobase-containing compound metabolic process; GO:0016319 (0.06) ! mushroom body development; GO:0016204 (0.06) ! determination of muscle attachment site; GO:0016199 (0.06) ! axon midline choice point recognition; GO:0009966 (0.06) ! regulation of signal transduction; GO:0007498 (0.06) ! mesoderm development; GO:0003008 (0.06) ! system process; GO:0001578 (0.06) ! microtubule bundle formation; GO:1903522 (0.05) ! regulation of blood circulation; GO:1903506 (0.05) ! regulation of nucleic acid-templated transcription; GO:1902582 (0.05) ! single-organism intracellular transport; GO:0090150 (0.05) ! establishment of protein localization to membrane; GO:0043009 (0.05) ! chordate embryonic development; GO:0042391 (0.05) ! regulation of membrane potential; GO:0042221 (0.05) ! response to chemical; GO:0034329 (0.05) ! cell junction assembly; GO:0015031 (0.05) ! protein transport; GO:0010468 (0.05) ! regulation of gene expression; GO:0007610 (0.05) ! behavior; GO:0007525 (0.05) ! somatic muscle development; GO:0007519 (0.05) ! skeletal muscle tissue development; GO:0006950 (0.05) ! response to stress; GO:0072657 (0.04) ! protein localization to membrane; GO:0060429 (0.04) ! epithelium development; GO:0051656 (0.04) ! establishment of organelle localization; GO:0051270 (0.04) ! regulation of cellular component movement; GO:0051050 (0.04) ! positive regulation of transport; GO:0045216 (0.04) ! cell-cell junction organization; GO:0040012 (0.04) ! regulation of locomotion; GO:0040011 (0.04) ! locomotion; GO:0032535 (0.04) ! regulation of cellular component size; GO:0031325 (0.04) ! positive regulation of cellular metabolic process; GO:0030155 (0.04) ! regulation of cell adhesion; GO:0016197 (0.04) ! endosomal transport; GO:0010604 (0.04) ! positive regulation of macromolecule metabolic process; GO:0009967 (0.04) ! positive regulation of signal transduction; GO:0009887 (0.04) ! organ morphogenesis; GO:0008016 (0.04) ! regulation of heart contraction; GO:0007626 (0.04) ! locomotory behavior; GO:0007527 (0.04) ! adult somatic muscle development; GO:0007517 (0.04) ! muscle organ development; GO:0007009 (0.04) ! plasma membrane organization; GO:0006897 (0.04) ! endocytosis; GO:0006886 (0.04) ! intracellular protein transport; GO:0006464 (0.04) ! cellular protein modification process; GO:0006355 (0.04) ! regulation of transcription, DNA-templated; GO:0003006 (0.04) ! developmental process involved in reproduction; GO:1902531 (0.03) ! regulation of intracellular signal transduction; GO:0090002 (0.03) ! establishment of protein localization to plasma membrane; GO:0060341 (0.03) ! regulation of cellular localization; GO:0051716 (0.03) ! cellular response to stimulus; GO:0051647 (0.03) ! nucleus localization; GO:0051241 (0.03) ! negative regulation of multicellular organismal process; GO:0048598 (0.03) ! embryonic morphogenesis; GO:0045944 (0.03) ! positive regulation of transcription from RNA polymerase II promoter; GO:0035556 (0.03) ! intracellular signal transduction; GO:0034333 (0.03) ! adherens junction assembly; GO:0033365 (0.03) ! protein localization to organelle; GO:0032970 (0.03) ! regulation of actin filament-based process; GO:0031175 (0.03) ! neuron projection development; GO:0030042 (0.03) ! actin filament depolymerization; GO:0022412 (0.03) ! cellular process involved in reproduction in multicellular organism; GO:0016477 (0.03) ! cell migration; GO:0010959 (0.03) ! regulation of metal ion transport; GO:0010927 (0.03) ! cellular component assembly involved in morphogenesis; GO:0007268 (0.03) ! chemical synaptic transmission; GO:0007155 (0.03) ! cell adhesion; GO:0007043 (0.03) ! cell-cell junction assembly; GO:0006997 (0.03) ! nucleus organization; GO:0006812 (0.03) ! cation transport; GO:0006612 (0.03) ! protein targeting to membrane; GO:0006468 (0.03) ! protein phosphorylation; GO:0006461 (0.03) ! protein complex assembly; GO:0003012 (0.03) ! muscle system process; GO:0002064 (0.03) ! epithelial cell development; GO:0002027 (0.03) ! regulation of heart rate; GO:0001952 (0.03) ! regulation of cell-matrix adhesion; GO:2000021 (0.02) ! regulation of ion homeostasis; GO:1904064 (0.02) ! positive regulation of cation transmembrane transport; GO:1903829 (0.02) ! positive regulation of cellular protein localization; GO:1903530 (0.02) ! regulation of secretion by cell; GO:1903523 (0.02) ! negative regulation of blood circulation; GO:1901576 (0.02) ! organic substance biosynthetic process; GO:0098602 (0.02) ! single organism cell adhesion; GO:0072661 (0.02) ! protein targeting to plasma membrane; GO:0070887 (0.02) ! cellular response to chemical stimulus; GO:0070509 (0.02) ! calcium ion import; GO:0060627 (0.02) ! regulation of vesicle-mediated transport; GO:0060361 (0.02) ! flight; GO:0055117 (0.02) ! regulation of cardiac muscle contraction; GO:0051646 (0.02) ! mitochondrion localization; GO:0051643 (0.02) ! endoplasmic reticulum localization; GO:0051222 (0.02) ! positive regulation of protein transport; GO:0050808 (0.02) ! synapse organization; GO:0048802 (0.02) ! notum morphogenesis; GO:0048734 (0.02) ! proboscis morphogenesis; GO:0046716 (0.02) ! muscle cell cellular homeostasis; GO:0045937 (0.02) ! positive regulation of phosphate metabolic process; GO:0045892 (0.02) ! negative regulation of transcription, DNA-templated; GO:0044271 (0.02) ! cellular nitrogen compound biosynthetic process; GO:0043623 (0.02) ! cellular protein complex assembly; GO:0042060 (0.02) ! wound healing; GO:0040023 (0.02) ! establishment of nucleus localization; GO:0040018 (0.02) ! positive regulation of multicellular organism growth; GO:0035220 (0.02) ! wing disc development; GO:0035150 (0.02) ! regulation of tube size; GO:0034453 (0.02) ! microtubule anchoring; GO:0033554 (0.02) ! cellular response to stress; GO:0033135 (0.02) ! regulation of peptidyl-serine phosphorylation; GO:0032940 (0.02) ! secretion by cell; GO:0032507 (0.02) ! maintenance of protein location in cell; GO:0032456 (0.02) ! endocytic recycling; GO:0032414 (0.02) ! positive regulation of ion transmembrane transporter activity; GO:0030705 (0.02) ! cytoskeleton-dependent intracellular transport; GO:0030534 (0.02) ! adult behavior; GO:0030522 (0.02) ! intracellular receptor signaling pathway; GO:0030431 (0.02) ! sleep; GO:0030334 (0.02) ! regulation of cell migration; GO:0030239 (0.02) ! myofibril assembly; GO:0030154 (0.02) ! cell differentiation; GO:0030048 (0.02) ! actin filament-based movement; GO:0019417 (0.02) ! sulfur oxidation; GO:0016070 (0.02) ! RNA metabolic process; GO:0010638 (0.02) ! positive regulation of organelle organization; GO:0010172 (0.02) ! embryonic body morphogenesis; GO:0010033 (0.02) ! response to organic substance; GO:0009628 (0.02) ! response to abiotic stimulus; GO:0009605 (0.02) ! response to external stimulus; GO:0008335 (0.02) ! female germline ring canal stabilization; GO:0007523 (0.02) ! larval visceral muscle development; GO:0007507 (0.02) ! heart development; GO:0007411 (0.02) ! axon guidance; GO:0007303 (0.02) ! cytoplasmic transport, nurse cell to oocyte; GO:0007166 (0.02) ! cell surface receptor signaling pathway; GO:0007094 (0.02) ! mitotic spindle assembly checkpoint; GO:0007044 (0.02) ! cell-substrate junction assembly; GO:0007018 (0.02) ! microtubule-based movement; GO:0006936 (0.02) ! muscle contraction; GO:0006913 (0.02) ! nucleocytoplasmic transport; GO:0006888 (0.02) ! ER to Golgi vesicle-mediated transport; GO:0003013 (0.02) ! circulatory system process; GO:0002119 (0.02) ! nematode larval development; GO:0002028 (0.02) ! regulation of sodium ion transport; GO:0002009 (0.02) ! morphogenesis of an epithelium; GO:0001954 (0.02) ! positive regulation of cell-matrix adhesion; GO:0001508 (0.02) ! action potential; GO:0000902 (0.02) ! cell morphogenesis; GO:0000281 (0.02) ! mitotic cytokinesis; GO:0000165 (0.02) ! MAPK cascade; GO:2001259 (0.01) ! positive regulation of cation channel activity; GO:2000651 (0.01) ! positive regulation of sodium ion transmembrane transporter activity; GO:1990126 (0.01) ! retrograde transport, endosome to plasma membrane; GO:1904025 (0.01) ! positive regulation of glucose catabolic process to lactate via pyruvate; GO:1903715 (0.01) ! regulation of aerobic respiration; GO:1903078 (0.01) ! positive regulation of protein localization to plasma membrane; GO:1902533 (0.01) ! positive regulation of intracellular signal transduction; GO:1902083 (0.01) ! negative regulation of peptidyl-cysteine S-nitrosylation; GO:1901653 (0.01) ! cellular response to peptide; GO:1901385 (0.01) ! regulation of voltage-gated calcium channel activity; GO:1901018 (0.01) ! positive regulation of potassium ion transmembrane transporter activity; GO:1900042 (0.01) ! positive regulation of interleukin-2 secretion; GO:1900024 (0.01) ! regulation of substrate adhesion-dependent cell spreading; GO:0099531 (0.01) ! presynaptic process involved in chemical synaptic transmission; GO:0099518 (0.01) ! vesicle cytoskeletal trafficking; GO:0099515 (0.01) ! actin filament-based transport; GO:0098910 (0.01) ! regulation of atrial cardiac muscle cell action potential; GO:0097320 (0.01) ! membrane tubulation; GO:0090324 (0.01) ! negative regulation of oxidative phosphorylation; GO:0090287 (0.01) ! regulation of cellular response to growth factor stimulus; GO:0090286 (0.01) ! cytoskeletal anchoring at nuclear membrane; GO:0090068 (0.01) ! positive regulation of cell cycle process; GO:0086010 (0.01) ! membrane depolarization during action potential; GO:0086001 (0.01) ! cardiac muscle cell action potential; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0071709 (0.01) ! membrane assembly; GO:0071526 (0.01) ! semaphorin-plexin signaling pathway; GO:0070972 (0.01) ! protein localization to endoplasmic reticulum; GO:0070885 (0.01) ! negative regulation of calcineurin-NFAT signaling cascade; GO:0070848 (0.01) ! response to growth factor; GO:0070830 (0.01) ! bicellular tight junction assembly; GO:0070372 (0.01) ! regulation of ERK1 and ERK2 cascade; GO:0061337 (0.01) ! cardiac conduction; GO:0061053 (0.01) ! somite development; GO:0061038 (0.01) ! uterus morphogenesis; GO:0060832 (0.01) ! oocyte animal/vegetal axis specification; GO:0060371 (0.01) ! regulation of atrial cardiac muscle cell membrane depolarization; GO:0060325 (0.01) ! face morphogenesis; GO:0060314 (0.01) ! regulation of ryanodine-sensitive calcium-release channel activity; GO:0060048 (0.01) ! cardiac muscle contraction; GO:0051893 (0.01) ! regulation of focal adhesion assembly; GO:0051764 (0.01) ! actin crosslink formation; GO:0051639 (0.01) ! actin filament network formation; GO:0051495 (0.01) ! positive regulation of cytoskeleton organization; GO:0051315 (0.01) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051271 (0.01) ! negative regulation of cellular component movement; GO:0051260 (0.01) ! protein homooligomerization; GO:0051090 (0.01) ! regulation of sequence-specific DNA binding transcription factor activity; GO:0051051 (0.01) ! negative regulation of transport; GO:0051017 (0.01) ! actin filament bundle assembly; GO:0050806 (0.01) ! positive regulation of synaptic transmission; GO:0048821 (0.01) ! erythrocyte development; GO:0048666 (0.01) ! neuron development; GO:0048644 (0.01) ! muscle organ morphogenesis; GO:0048633 (0.01) ! positive regulation of skeletal muscle tissue growth; GO:0048588 (0.01) ! developmental cell growth; GO:0048384 (0.01) ! retinoic acid receptor signaling pathway; GO:0048041 (0.01) ! focal adhesion assembly; GO:0046928 (0.01) ! regulation of neurotransmitter secretion; GO:0046622 (0.01) ! positive regulation of organ growth; GO:0046578 (0.01) ! regulation of Ras protein signal transduction; GO:0046331 (0.01) ! lateral inhibition; GO:0045908 (0.01) ! negative regulation of vasodilation; GO:0045907 (0.01) ! positive regulation of vasoconstriction; GO:0045820 (0.01) ! negative regulation of glycolytic process; GO:0045793 (0.01) ! positive regulation of cell size; GO:0045747 (0.01) ! positive regulation of Notch signaling pathway; GO:0045186 (0.01) ! zonula adherens assembly; GO:0045162 (0.01) ! clustering of voltage-gated sodium channels; GO:0045104 (0.01) ! intermediate filament cytoskeleton organization; GO:0045087 (0.01) ! innate immune response; GO:0045035 (0.01) ! sensory organ precursor cell division; GO:0044719 (0.01) ! regulation of imaginal disc-derived wing size; GO:0044703 (0.01) ! multi-organism reproductive process; GO:0044351 (0.01) ! macropinocytosis; GO:0043578 (0.01) ! nuclear matrix organization; GO:0043087 (0.01) ! regulation of GTPase activity; GO:0043043 (0.01) ! peptide biosynthetic process; GO:0043001 (0.01) ! Golgi to plasma membrane protein transport; GO:0042692 (0.01) ! muscle cell differentiation; GO:0042493 (0.01) ! response to drug; GO:0042330 (0.01) ! taxis; GO:0042307 (0.01) ! positive regulation of protein import into nucleus; GO:0042127 (0.01) ! regulation of cell proliferation; GO:0040005 (0.01) ! chitin-based cuticle attachment to epithelium; GO:0036010 (0.01) ! protein localization to endosome; GO:0035994 (0.01) ! response to muscle stretch; GO:0035372 (0.01) ! protein localization to microtubule; GO:0035357 (0.01) ! peroxisome proliferator activated receptor signaling pathway; GO:0035264 (0.01) ! multicellular organism growth; GO:0035162 (0.01) ! embryonic hemopoiesis; GO:0034501 (0.01) ! protein localization to kinetochore; GO:0034446 (0.01) ! substrate adhesion-dependent cell spreading; GO:0034220 (0.01) ! ion transmembrane transport; GO:0033137 (0.01) ! negative regulation of peptidyl-serine phosphorylation; GO:0032509 (0.01) ! endosome transport via multivesicular body sorting pathway; GO:0032458 (0.01) ! slow endocytic recycling; GO:0032446 (0.01) ! protein modification by small protein conjugation; GO:0031647 (0.01) ! regulation of protein stability; GO:0031581 (0.01) ! hemidesmosome assembly; GO:0031532 (0.01) ! actin cytoskeleton reorganization; GO:0031134 (0.01) ! sister chromatid biorientation; GO:0030866 (0.01) ! cortical actin cytoskeleton organization; GO:0030834 (0.01) ! regulation of actin filament depolymerization; GO:0030707 (0.01) ! ovarian follicle cell development; GO:0030587 (0.01) ! sorocarp development; GO:0030335 (0.01) ! positive regulation of cell migration; GO:0030177 (0.01) ! positive regulation of Wnt signaling pathway; GO:0030049 (0.01) ! muscle filament sliding; GO:0030041 (0.01) ! actin filament polymerization; GO:0030035 (0.01) ! microspike assembly; GO:0023061 (0.01) ! signal release; GO:0021952 (0.01) ! central nervous system projection neuron axonogenesis; GO:0021692 (0.01) ! cerebellar Purkinje cell layer morphogenesis; GO:0019226 (0.01) ! transmission of nerve impulse; GO:0018105 (0.01) ! peptidyl-serine phosphorylation; GO:0017158 (0.01) ! regulation of calcium ion-dependent exocytosis; GO:0016358 (0.01) ! dendrite development; GO:0016337 (0.01) ! single organismal cell-cell adhesion; GO:0014894 (0.01) ! response to denervation involved in regulation of muscle adaptation; GO:0014883 (0.01) ! transition between fast and slow fiber; GO:0014823 (0.01) ! response to activity; GO:0014809 (0.01) ! regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion; GO:0014732 (0.01) ! skeletal muscle atrophy; GO:0014728 (0.01) ! regulation of the force of skeletal muscle contraction; GO:0010881 (0.01) ! regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; GO:0010812 (0.01) ! negative regulation of cell-substrate adhesion; GO:0010797 (0.01) ! regulation of multivesicular body size involved in endosome transport; GO:0010735 (0.01) ! positive regulation of transcription via serum response element binding; GO:0010721 (0.01) ! negative regulation of cell development; GO:0010632 (0.01) ! regulation of epithelial cell migration; GO:0010459 (0.01) ! negative regulation of heart rate; GO:0010045 (0.01) ! response to nickel cation; GO:0009607 (0.01) ! response to biotic stimulus; GO:0009566 (0.01) ! fertilization; GO:0009266 (0.01) ! response to temperature stimulus; GO:0008362 (0.01) ! chitin-based embryonic cuticle biosynthetic process; GO:0008360 (0.01) ! regulation of cell shape; GO:0007628 (0.01) ! adult walking behavior; GO:0007605 (0.01) ! sensory perception of sound; GO:0007528 (0.01) ! neuromuscular junction development; GO:0007416 (0.01) ! synapse assembly; GO:0007399 (0.01) ! nervous system development; GO:0007274 (0.01) ! neuromuscular synaptic transmission; GO:0007186 (0.01) ! G-protein coupled receptor signaling pathway; GO:0007163 (0.01) ! establishment or maintenance of cell polarity; GO:0007097 (0.01) ! nuclear migration; GO:0007041 (0.01) ! lysosomal transport; GO:0007030 (0.01) ! Golgi organization; GO:0007016 (0.01) ! cytoskeletal anchoring at plasma membrane; GO:0006972 (0.01) ! hyperosmotic response; GO:0006939 (0.01) ! smooth muscle contraction; GO:0006898 (0.01) ! receptor-mediated endocytosis; GO:0006606 (0.01) ! protein import into nucleus; GO:0006405 (0.01) ! RNA export from nucleus; GO:0006396 (0.01) ! RNA processing; GO:0006366 (0.01) ! transcription from RNA polymerase II promoter; GO:0006325 (0.01) ! chromatin organization; GO:0002682 (0.01) ! regulation of immune system process; GO:0002576 (0.01) ! platelet degranulation; GO:0001947 (0.01) ! heart looping; GO:0001934 (0.01) ! positive regulation of protein phosphorylation; GO:0001654 (0.01) ! eye development; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter GO:0044464 (0.99) ! cell part; GO:0044424 (0.97) ! intracellular part; GO:0044422 (0.75) ! organelle part; GO:0043226 (0.73) ! organelle; GO:0044446 (0.71) ! intracellular organelle part; GO:0043229 (0.70) ! intracellular organelle; GO:0044444 (0.68) ! cytoplasmic part; GO:0005737 (0.66) ! cytoplasm; GO:0016020 (0.52) ! membrane; GO:0043232 (0.51) ! intracellular non-membrane-bounded organelle; GO:0044430 (0.50) ! cytoskeletal part; GO:0044425 (0.44) ! membrane part; GO:0005856 (0.43) ! cytoskeleton; GO:0043227 (0.42) ! membrane-bounded organelle; GO:0005886 (0.42) ! plasma membrane; GO:0042995 (0.38) ! cell projection; GO:0032991 (0.38) ! macromolecular complex; GO:0043234 (0.37) ! protein complex; GO:0043231 (0.37) ! intracellular membrane-bounded organelle; GO:0044459 (0.36) ! plasma membrane part; GO:0030054 (0.36) ! cell junction; GO:0030055 (0.32) ! cell-substrate junction; GO:0005912 (0.31) ! adherens junction; GO:0044449 (0.30) ! contractile fiber part; GO:0005924 (0.28) ! cell-substrate adherens junction; GO:0044448 (0.27) ! cell cortex part; GO:0005739 (0.25) ! mitochondrion; GO:0042383 (0.24) ! sarcolemma; GO:0044428 (0.23) ! nuclear part; GO:0032432 (0.23) ! actin filament bundle; GO:0005925 (0.23) ! focal adhesion; GO:0005911 (0.23) ! cell-cell junction; GO:0030863 (0.22) ! cortical cytoskeleton; GO:0030864 (0.21) ! cortical actin cytoskeleton; GO:0016328 (0.21) ! lateral plasma membrane; GO:0005913 (0.21) ! cell-cell adherens junction; GO:0001725 (0.21) ! stress fiber; GO:0031252 (0.20) ! cell leading edge; GO:0030486 (0.20) ! smooth muscle dense body; GO:0005923 (0.20) ! bicellular tight junction; GO:1990357 (0.19) ! terminal web; GO:1902494 (0.19) ! catalytic complex; GO:0097433 (0.19) ! dense body; GO:0090637 (0.19) ! inner dense plaque of desmosome; GO:0090636 (0.19) ! outer dense plaque of desmosome; GO:0030027 (0.19) ! lamellipodium; GO:0005915 (0.19) ! zonula adherens; GO:1990234 (0.18) ! transferase complex; GO:0070013 (0.17) ! intracellular organelle lumen; GO:0005623 (0.17) ! cell; GO:0045254 (0.16) ! pyruvate dehydrogenase complex; GO:0045252 (0.16) ! oxoglutarate dehydrogenase complex; GO:0005759 (0.16) ! mitochondrial matrix; GO:0097458 (0.14) ! neuron part; GO:0044463 (0.14) ! cell projection part; GO:0099513 (0.12) ! polymeric cytoskeletal fiber; GO:0005829 (0.12) ! cytosol; GO:0005654 (0.12) ! nucleoplasm; GO:0005634 (0.12) ! nucleus; GO:0098590 (0.11) ! plasma membrane region; GO:0044421 (0.11) ! extracellular region part; GO:0031982 (0.10) ! vesicle; GO:0016021 (0.10) ! integral component of membrane; GO:0044437 (0.09) ! vacuolar part; GO:0044433 (0.09) ! cytoplasmic vesicle part; GO:0031988 (0.09) ! membrane-bounded vesicle; GO:0043209 (0.08) ! myelin sheath; GO:0043159 (0.08) ! acrosomal matrix; GO:0042645 (0.08) ! mitochondrial nucleoid; GO:0030175 (0.08) ! filopodium; GO:0009353 (0.08) ! mitochondrial oxoglutarate dehydrogenase complex; GO:0005967 (0.08) ! mitochondrial pyruvate dehydrogenase complex; GO:0005960 (0.08) ! glycine cleavage complex; GO:0005929 (0.08) ! cilium; GO:0070062 (0.07) ! extracellular exosome; GO:0033267 (0.07) ! axon part; GO:0005874 (0.07) ! microtubule; GO:1990752 (0.06) ! microtubule end; GO:0098797 (0.06) ! plasma membrane protein complex; GO:0030426 (0.06) ! growth cone; GO:0016324 (0.06) ! apical plasma membrane; GO:0015629 (0.06) ! actin cytoskeleton; GO:0005875 (0.06) ! microtubule associated complex; GO:0045169 (0.05) ! fusome; GO:0044451 (0.05) ! nucleoplasm part; GO:0044295 (0.05) ! axonal growth cone; GO:0035371 (0.05) ! microtubule plus-end; GO:0031253 (0.05) ! cell projection membrane; GO:0031090 (0.05) ! organelle membrane; GO:0030018 (0.05) ! Z disc; GO:0005927 (0.05) ! muscle tendon junction; GO:0000235 (0.05) ! astral microtubule; GO:0043005 (0.04) ! neuron projection; GO:0030056 (0.04) ! hemidesmosome; GO:0008091 (0.04) ! spectrin; GO:0098805 (0.03) ! whole membrane; GO:0098588 (0.03) ! bounding membrane of organelle; GO:0048471 (0.03) ! perinuclear region of cytoplasm; GO:0045202 (0.03) ! synapse; GO:0044456 (0.03) ! synapse part; GO:0044427 (0.03) ! chromosomal part; GO:0043235 (0.03) ! receptor complex; GO:0043034 (0.03) ! costamere; GO:0031965 (0.03) ! nuclear membrane; GO:0031430 (0.03) ! M band; GO:0016010 (0.03) ! dystrophin-associated glycoprotein complex; GO:0009925 (0.03) ! basal plasma membrane; GO:0005938 (0.03) ! cell cortex; GO:0005884 (0.03) ! actin filament; GO:0005665 (0.03) ! DNA-directed RNA polymerase II, core complex; GO:0005643 (0.03) ! nuclear pore; GO:0005635 (0.03) ! nuclear envelope; GO:0098589 (0.02) ! membrane region; GO:0070938 (0.02) ! contractile ring; GO:0043292 (0.02) ! contractile fiber; GO:0043025 (0.02) ! neuronal cell body; GO:0031941 (0.02) ! filamentous actin; GO:0031594 (0.02) ! neuromuscular junction; GO:0031527 (0.02) ! filopodium membrane; GO:0031256 (0.02) ! leading edge membrane; GO:0031226 (0.02) ! intrinsic component of plasma membrane; GO:0031012 (0.02) ! extracellular matrix; GO:0016023 (0.02) ! cytoplasmic, membrane-bounded vesicle; GO:0015630 (0.02) ! microtubule cytoskeleton; GO:0008305 (0.02) ! integrin complex; GO:0005882 (0.02) ! intermediate filament; GO:0005871 (0.02) ! kinesin complex; GO:0005865 (0.02) ! striated muscle thin filament; GO:0005768 (0.02) ! endosome; GO:0005622 (0.02) ! intracellular; GO:0005615 (0.02) ! extracellular space; GO:0000776 (0.02) ! kinetochore; GO:0099738 (0.01) ! cell cortex region; GO:0099503 (0.01) ! secretory vesicle; GO:0072686 (0.01) ! mitotic spindle; GO:0070852 (0.01) ! cell body fiber; GO:0055120 (0.01) ! striated muscle dense body; GO:0055038 (0.01) ! recycling endosome membrane; GO:0055037 (0.01) ! recycling endosome; GO:0045121 (0.01) ! membrane raft; GO:0045111 (0.01) ! intermediate filament cytoskeleton; GO:0044615 (0.01) ! nuclear pore nuclear basket; GO:0044454 (0.01) ! nuclear chromosome part; GO:0044432 (0.01) ! endoplasmic reticulum part; GO:0044306 (0.01) ! neuron projection terminus; GO:0043203 (0.01) ! axon hillock; GO:0043197 (0.01) ! dendritic spine; GO:0043194 (0.01) ! axon initial segment; GO:0042405 (0.01) ! nuclear inclusion body; GO:0034993 (0.01) ! LINC complex; GO:0034703 (0.01) ! cation channel complex; GO:0034399 (0.01) ! nuclear periphery; GO:0033270 (0.01) ! paranode region of axon; GO:0033268 (0.01) ! node of Ranvier; GO:0032587 (0.01) ! ruffle membrane; GO:0032155 (0.01) ! cell division site part; GO:0031674 (0.01) ! I band; GO:0031672 (0.01) ! A band; GO:0031143 (0.01) ! pseudopodium; GO:0031093 (0.01) ! platelet alpha granule lumen; GO:0030529 (0.01) ! intracellular ribonucleoprotein complex; GO:0030424 (0.01) ! axon; GO:0030133 (0.01) ! transport vesicle; GO:0030017 (0.01) ! sarcomere; GO:0030016 (0.01) ! myofibril; GO:0019898 (0.01) ! extrinsic component of membrane; GO:0016605 (0.01) ! PML body; GO:0016529 (0.01) ! sarcoplasmic reticulum; GO:0016528 (0.01) ! sarcoplasm; GO:0016363 (0.01) ! nuclear matrix; GO:0016327 (0.01) ! apicolateral plasma membrane; GO:0016235 (0.01) ! aggresome; GO:0014731 (0.01) ! spectrin-associated cytoskeleton; GO:0014704 (0.01) ! intercalated disc; GO:0014069 (0.01) ! postsynaptic density; GO:0009986 (0.01) ! cell surface; GO:0005930 (0.01) ! axoneme; GO:0005903 (0.01) ! brush border; GO:0005887 (0.01) ! integral component of plasma membrane; GO:0005868 (0.01) ! cytoplasmic dynein complex; GO:0005815 (0.01) ! microtubule organizing center; GO:0005802 (0.01) ! trans-Golgi network; GO:0005794 (0.01) ! Golgi apparatus; GO:0005770 (0.01) ! late endosome; GO:0005730 (0.01) ! nucleolus; GO:0005667 (0.01) ! transcription factor complex; GO:0005640 (0.01) ! nuclear outer membrane; GO:0005576 (0.01) ! extracellular region; GO:0001917 (0.01) ! photoreceptor inner segment; GO:0000785 (0.01) ! chromatin; GO:0000777 (0.01) ! condensed chromosome kinetochore 2 4583999-4608319 (17p13.2) Muscle - Skeletal: 280.65; Kidney - Cortex: 25.27; Fallopian Tube: 14.21; Ovary: 9.72; Adipose - Visceral (Omentum): 9.01; Esophagus - Muscularis: 8.62; Heart - Left Ventricle: 7.63; Lung: 6.71; Cervix - Ectocervix: 6.30; Cervix - Endocervix: 5.88; Nerve - Tibial: 5.83; Heart - Atrial Appendage: 5.61; Uterus: 5.14; Esophagus - Gastroesophageal Junction: 5.07; Bladder: 4.64; Vagina: 3.63; Prostate: 3.11; Breast - Mammary Tissue: 2.85; Pituitary: 2.68; Adipose - Subcutaneous: 2.48; Esophagus - Mucosa: 2.43; Testis: 2.14; Artery - Coronary: 1.79; Thyroid: 1.63; Colon - Sigmoid: 1.38; Spleen: 1.22; Small Intestine - Terminal Ileum: 1.22; Minor Salivary Gland: 1.18; Skin - Sun Exposed (Lower leg): 1.01; Skin - Not Sun Exposed (Suprapubic): 0.88; Stomach: 0.86; Colon - Transverse: 0.78; Artery - Tibial: 0.78; Artery - Aorta: 0.62; Brain - Hippocampus: 0.61; Brain - Cerebellum: 0.54; Brain - Cortex: 0.52; Brain - Caudate (basal ganglia): 0.42; Brain - Frontal Cortex (BA9): 0.40; Brain - Cerebellar Hemisphere: 0.39; Brain - Spinal cord (cervical c-1): 0.37; Brain - Putamen (basal ganglia): 0.36; Brain - Substantia nigra: 0.33; Brain - Anterior cingulate cortex (BA24): 0.32; Brain - Amygdala: 0.32; Brain - Hypothalamus: 0.32; Brain - Nucleus accumbens (basal ganglia): 0.27; Pancreas: 0.27; Adrenal Gland: 0.14; Cells - EBV-transformed lymphocytes: 0.08; Liver: 0.08; Whole Blood: 0.08; Cells - Transformed fibroblasts: 0.06; MEPAPDAQEARTVREALGRYEAALEGAVRALHEDMRGLQRGVERRVAEAMRLAGPLARTVADLQRDNQRLQAQLERLTRQVEALGLASGMSPVPGTPGTPSPPPAPGVPDRAPRLGSARFASHATFSLSGRGQSLDHDEASESEMRKTSNSCIMENGHQPGAGPGDGPPEIAQNFSAPDPPRPRPVSLSLRLPHQPVTAITRVSDRFSGETSAAALSPMSAATLGGLNPSPSEVITPWTPSPSEKNSSFTWSVPSSGYGAVTASKHSNSPPLVTPPQSPVSPQPPAITQVHRQGERRRELVRSQTLPRTSEAQARKALFEKWEQETAAGKGKGEARARLKRSQSFGVASASSIKQILLEWCRSKTLGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNSLSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYVQSLYNHLRRFE TM4SF5 Transmembrane 4 L6 family member 5 T4S5_HUMAN (O14894-1) GO:0015370 (0.50) ! solute:sodium symporter activity; GO:0005326 (0.50) ! neurotransmitter transporter activity GO:0048856 (1.00) ! anatomical structure development; GO:0044767 (1.00) ! single-organism developmental process; GO:0044763 (0.76) ! single-organism cellular process; GO:2000227 (0.64) ! negative regulation of pancreatic A cell differentiation; GO:2000077 (0.64) ! negative regulation of type B pancreatic cell development; GO:0090104 (0.64) ! pancreatic epsilon cell differentiation; GO:0031018 (0.64) ! endocrine pancreas development; GO:0042246 (0.36) ! tissue regeneration; GO:0044765 (0.34) ! single-organism transport GO:0016021 (1.00) ! integral component of membrane; GO:0005887 (0.05) ! integral component of plasma membrane GO:0005887 ! integral component of plasma membrane GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 2 4771884-4783213 (17p13.2) Liver: 126.20; Small Intestine - Terminal Ileum: 53.03; Colon - Transverse: 10.47; Stomach: 8.42; Kidney - Cortex: 8.34; Pancreas: 0.33; Testis: 0.20; Adrenal Gland: 0.12; Colon - Sigmoid: 0.11; Cervix - Endocervix: 0.09; MCTGKCARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMVLCPGIAAVRAGGKGCCGAGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPRCLMNGEWGYHFEDTAGAYLLNRTLWDRCEAPPRVVPWNVTLFSLLVAASCLEIVLCGIQLVNATIGVFCGDCRKKQDTPH VMO1 Vitelline membrane outer layer protein 1 homolog VMO1_HUMAN (Q7Z5L0-1) GO:0016787 (0.53) ! hydrolase activity; GO:0008061 (0.36) ! chitin binding; GO:0004568 (0.36) ! chitinase activity; GO:0004551 (0.17) ! nucleotide diphosphatase activity; GO:0004035 (0.17) ! alkaline phosphatase activity; GO:0030246 (0.15) ! carbohydrate binding; GO:0004930 (0.14) ! G-protein coupled receptor activity GO:0065007 (0.36) ! biological regulation; GO:0048856 (0.35) ! anatomical structure development; GO:0050794 (0.32) ! regulation of cellular process; GO:0071711 (0.25) ! basement membrane organization; GO:0033334 (0.25) ! fin morphogenesis; GO:0033333 (0.25) ! fin development; GO:0006032 (0.25) ! chitin catabolic process; GO:0043569 (0.12) ! negative regulation of insulin-like growth factor receptor signaling pathway; GO:0051965 (0.10) ! positive regulation of synapse assembly; GO:0007422 (0.10) ! peripheral nervous system development; GO:0007186 (0.10) ! G-protein coupled receptor signaling pathway; GO:0001895 (0.07) ! retina homeostasis GO:0070062 (1.00) ! extracellular exosome GO:0070062 ! extracellular exosome GO:0005576 ! extracellular region 3 4785285-4786433 (17p13.2) Pituitary: 36.65; Spleen: 27.55; Lung: 12.54; Artery - Aorta: 11.17; Artery - Coronary: 7.36; Nerve - Tibial: 6.98; Cervix - Endocervix: 6.64; Liver: 5.87; Minor Salivary Gland: 5.44; Brain - Spinal cord (cervical c-1): 5.05; Adipose - Visceral (Omentum): 4.66; Prostate: 4.35; Adipose - Subcutaneous: 3.86; Artery - Tibial: 3.81; Vagina: 3.72; Brain - Cerebellum: 3.67; Brain - Cerebellar Hemisphere: 3.66; Brain - Hypothalamus: 3.39; Small Intestine - Terminal Ileum: 3.22; Cells - Transformed fibroblasts: 3.14; Skin - Sun Exposed (Lower leg): 3.11; Uterus: 3.09; Skin - Not Sun Exposed (Suprapubic): 3.00; Breast - Mammary Tissue: 2.77; Brain - Frontal Cortex (BA9): 2.72; Brain - Cortex: 2.68; Kidney - Cortex: 2.65; Brain - Substantia nigra: 2.64; Adrenal Gland: 2.63; Colon - Sigmoid: 2.57; Fallopian Tube: 2.49; Cervix - Ectocervix: 2.43; Brain - Hippocampus: 2.40; Thyroid: 2.35; Brain - Nucleus accumbens (basal ganglia): 2.33; Brain - Anterior cingulate cortex (BA24): 2.28; Whole Blood: 2.10; Esophagus - Mucosa: 2.06; Colon - Transverse: 1.99; Brain - Amygdala: 1.98; Brain - Caudate (basal ganglia): 1.89; Bladder: 1.85; Esophagus - Gastroesophageal Junction: 1.77; Brain - Putamen (basal ganglia): 1.67; Esophagus - Muscularis: 1.63; Ovary: 1.59; Testis: 1.50; Stomach: 1.40; Heart - Atrial Appendage: 1.31; Pancreas: 0.69; Muscle - Skeletal: 0.60; Heart - Left Ventricle: 0.45; Cells - EBV-transformed lymphocytes: 0.14; MERGAGAKLLPLLLLLRATGFTCAQTDGRNGYTAVIEVTSGGPWGDWAWPEMCPDGFFASGFSLKVEPPQGIPGDDTALNGIRLHCARGNVLGNTHVVESQSGSWGEWSEPLWCRGGAYLVAFSLRVEAPTTLGDNTAANNVRFRCSDGEELQGPGLSWGDFGDWSDHCPKGACGLQTKIQGPRGLGDDTALNDARLFCCRS C17orf100 Uncharacterized protein C17orf100 CQ100_HUMAN (A8MU93-1) GO:0003824 (0.46) ! catalytic activity; GO:0016787 (0.27) ! hydrolase activity; GO:0016740 (0.25) ! transferase activity; GO:0052689 (0.23) ! carboxylic ester hydrolase activity; GO:0033040 (0.22) ! sour taste receptor activity; GO:0005262 (0.22) ! calcium channel activity; GO:1901363 (0.20) ! heterocyclic compound binding; GO:0097159 (0.20) ! organic cyclic compound binding; GO:0003881 (0.20) ! CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity; GO:0044822 (0.15) ! poly(A) RNA binding; GO:0008134 (0.15) ! transcription factor binding; GO:0003712 (0.15) ! transcription cofactor activity; GO:0001078 (0.15) ! transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0001047 (0.15) ! core promoter binding; GO:0000978 (0.15) ! RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0051015 (0.06) ! actin filament binding; GO:0030898 (0.06) ! actin-dependent ATPase activity; GO:0008861 (0.06) ! formate C-acetyltransferase activity; GO:0005547 (0.06) ! phosphatidylinositol-3,4,5-trisphosphate binding; GO:0005546 (0.06) ! phosphatidylinositol-4,5-bisphosphate binding; GO:0005524 (0.06) ! ATP binding; GO:0005516 (0.06) ! calmodulin binding; GO:0000146 (0.06) ! microfilament motor activity GO:0050794 (0.87) ! regulation of cellular process; GO:0030308 (0.84) ! negative regulation of cell growth; GO:0009987 (0.20) ! cellular process; GO:0044699 (0.17) ! single-organism process; GO:0044763 (0.14) ! single-organism cellular process; GO:0071704 (0.09) ! organic substance metabolic process; GO:0044710 (0.09) ! single-organism metabolic process; GO:0044238 (0.09) ! primary metabolic process; GO:0044237 (0.09) ! cellular metabolic process; GO:0006810 (0.09) ! transport; GO:0048856 (0.08) ! anatomical structure development; GO:0006928 (0.08) ! movement of cell or subcellular component; GO:0051716 (0.06) ! cellular response to stimulus; GO:0051017 (0.05) ! actin filament bundle assembly; GO:0030048 (0.05) ! actin filament-based movement; GO:0007399 (0.05) ! nervous system development; GO:0006892 (0.05) ! post-Golgi vesicle-mediated transport; GO:0006567 (0.05) ! threonine catabolic process; GO:0006006 (0.05) ! glucose metabolic process; GO:0071468 (0.04) ! cellular response to acidic pH; GO:0050982 (0.04) ! detection of mechanical stimulus; GO:0050915 (0.04) ! sensory perception of sour taste; GO:0006812 (0.04) ! cation transport; GO:0006661 (0.04) ! phosphatidylinositol biosynthetic process; GO:0001581 (0.04) ! detection of chemical stimulus involved in sensory perception of sour taste; GO:0048870 (0.03) ! cell motility; GO:0048839 (0.03) ! inner ear development; GO:0045669 (0.03) ! positive regulation of osteoblast differentiation; GO:0043032 (0.03) ! positive regulation of macrophage activation; GO:0042771 (0.03) ! intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0035458 (0.03) ! cellular response to interferon-beta; GO:0035457 (0.03) ! cellular response to interferon-alpha; GO:0016337 (0.03) ! single organismal cell-cell adhesion; GO:0007339 (0.03) ! binding of sperm to zona pellucida; GO:0006357 (0.03) ! regulation of transcription from RNA polymerase II promoter GO:0044464 (0.99) ! cell part; GO:0044424 (0.98) ! intracellular part; GO:0043226 (0.96) ! organelle; GO:0043227 (0.95) ! membrane-bounded organelle; GO:0043229 (0.93) ! intracellular organelle; GO:0043231 (0.92) ! intracellular membrane-bounded organelle; GO:0005737 (0.88) ! cytoplasm; GO:0005634 (0.81) ! nucleus; GO:0043234 (0.77) ! protein complex; GO:0016459 (0.76) ! myosin complex; GO:0044444 (0.68) ! cytoplasmic part; GO:0031988 (0.60) ! membrane-bounded vesicle; GO:0016020 (0.59) ! membrane; GO:0042995 (0.44) ! cell projection; GO:0016023 (0.44) ! cytoplasmic, membrane-bounded vesicle; GO:0044425 (0.34) ! membrane part; GO:0044421 (0.30) ! extracellular region part; GO:0030139 (0.30) ! endocytic vesicle; GO:0005886 (0.30) ! plasma membrane; GO:0070062 (0.27) ! extracellular exosome; GO:0043232 (0.26) ! intracellular non-membrane-bounded organelle; GO:0045335 (0.24) ! phagocytic vesicle; GO:0044459 (0.24) ! plasma membrane part; GO:0005829 (0.24) ! cytosol; GO:0045160 (0.18) ! myosin I complex; GO:0042641 (0.18) ! actomyosin; GO:0032982 (0.18) ! myosin filament; GO:0032009 (0.18) ! early phagosome; GO:0031941 (0.18) ! filamentous actin; GO:0031252 (0.18) ! cell leading edge; GO:0031143 (0.18) ! pseudopodium; GO:0031090 (0.18) ! organelle membrane; GO:0005938 (0.18) ! cell cortex; GO:0005903 (0.18) ! brush border; GO:0005794 (0.14) ! Golgi apparatus; GO:0005654 (0.13) ! nucleoplasm; GO:0098858 (0.11) ! actin-based cell projection; GO:0098589 (0.11) ! membrane region; GO:0097458 (0.11) ! neuron part; GO:0070685 (0.11) ! macropinocytic cup; GO:0048471 (0.11) ! perinuclear region of cytoplasm; GO:0044463 (0.11) ! cell projection part; GO:0044291 (0.11) ! cell-cell contact zone; GO:0016460 (0.11) ! myosin II complex; GO:0005884 (0.11) ! actin filament; GO:0005856 (0.11) ! cytoskeleton; GO:0005773 (0.11) ! vacuole; GO:0001891 (0.11) ! phagocytic cup; GO:0001726 (0.11) ! ruffle; GO:0001725 (0.11) ! stress fiber; GO:0000139 (0.11) ! Golgi membrane; GO:0044451 (0.08) ! nucleoplasm part; GO:0005730 (0.08) ! nucleolus; GO:1990753 (0.06) ! equatorial cell cortex; GO:0097513 (0.06) ! myosin II filament; GO:0097204 (0.06) ! phagocytic cup base; GO:0071944 (0.06) ! cell periphery; GO:0060171 (0.06) ! stereocilium membrane; GO:0045334 (0.06) ! clathrin-coated endocytic vesicle; GO:0045179 (0.06) ! apical cortex; GO:0045121 (0.06) ! membrane raft; GO:0043209 (0.06) ! myelin sheath; GO:0032593 (0.06) ! insulin-responsive compartment; GO:0032588 (0.06) ! trans-Golgi network membrane; GO:0032420 (0.06) ! stereocilium; GO:0032154 (0.06) ! cleavage furrow; GO:0031965 (0.06) ! nuclear membrane; GO:0031254 (0.06) ! cell trailing edge; GO:0030426 (0.06) ! growth cone; GO:0030424 (0.06) ! axon; GO:0030175 (0.06) ! filopodium; GO:0030016 (0.06) ! myofibril; GO:0016591 (0.06) ! DNA-directed RNA polymerase II, holoenzyme; GO:0016328 (0.06) ! lateral plasma membrane; GO:0010008 (0.06) ! endosome membrane; GO:0009925 (0.06) ! basal plasma membrane; GO:0005905 (0.06) ! clathrin-coated pit; GO:0005902 (0.06) ! microvillus; GO:0005826 (0.06) ! actomyosin contractile ring; GO:0005769 (0.06) ! early endosome; GO:0005643 (0.06) ! nuclear pore; GO:0005576 (0.06) ! extracellular region; GO:0001931 (0.06) ! uropod; GO:0000331 (0.06) ! contractile vacuole; GO:0043235 (0.03) ! receptor complex; GO:0034703 (0.03) ! cation channel complex; GO:0016021 (0.03) ! integral component of membrane; GO:0009986 (0.03) ! cell surface; GO:0005615 (0.03) ! extracellular space; GO:0042405 (0.02) ! nuclear inclusion body; GO:0020011 (0.02) ! apicoplast; GO:0016607 (0.02) ! nuclear speck 1 6651718-6693202 (17p13.1) Pituitary: 3.85; Skin - Not Sun Exposed (Suprapubic): 2.29; Skin - Sun Exposed (Lower leg): 2.19; Testis: 2.12; Thyroid: 1.96; Esophagus - Mucosa: 1.91; Brain - Nucleus accumbens (basal ganglia): 1.24; Spleen: 1.17; Cells - EBV-transformed lymphocytes: 1.11; Brain - Cerebellum: 0.78; Brain - Hypothalamus: 0.77; Brain - Cerebellar Hemisphere: 0.77; Brain - Frontal Cortex (BA9): 0.74; Brain - Cortex: 0.73; Brain - Caudate (basal ganglia): 0.72; Vagina: 0.65; Prostate: 0.64; Fallopian Tube: 0.60; Minor Salivary Gland: 0.60; Small Intestine - Terminal Ileum: 0.58; Brain - Putamen (basal ganglia): 0.52; Cervix - Ectocervix: 0.52; Brain - Anterior cingulate cortex (BA24): 0.50; Cervix - Endocervix: 0.47; Brain - Spinal cord (cervical c-1): 0.44; Bladder: 0.43; Lung: 0.40; Brain - Hippocampus: 0.38; Pancreas: 0.33; Brain - Amygdala: 0.30; Brain - Substantia nigra: 0.30; Breast - Mammary Tissue: 0.24; Kidney - Cortex: 0.21; Uterus: 0.20; Liver: 0.19; Ovary: 0.19; Colon - Transverse: 0.17; Cells - Transformed fibroblasts: 0.15; Stomach: 0.14; Colon - Sigmoid: 0.14; Adipose - Visceral (Omentum): 0.13; Adrenal Gland: 0.11; Esophagus - Muscularis: 0.10; MASARGAKQSSPRVGTTRYTETSTVRVETSSHRVETSSRRVETSQRRSEGPSLSPSGKRLPRILEASSRHVESSSQRTETTSRHVRASSLRVETSLHCAESPTPRPSRPPARTKKRPDEMLLPKGHQGARALSQDRKASSCQPASQLPGGPIIFGFMETNHKSM TMEM256 Transmembrane protein 256 TM256_HUMAN (Q8N2U0-1) GO:0022892 (0.57) ! substrate-specific transporter activity; GO:0017128 (0.55) ! phospholipid scramblase activity; GO:0003824 (0.47) ! catalytic activity; GO:0008865 (0.45) ! fructokinase activity; GO:0004454 (0.45) ! ketohexokinase activity; GO:0042803 (0.04) ! protein homodimerization activity; GO:0030955 (0.04) ! potassium ion binding; GO:0015081 (0.04) ! sodium ion transmembrane transporter activity; GO:0009678 (0.04) ! hydrogen-translocating pyrophosphatase activity; GO:0005509 (0.04) ! calcium ion binding; GO:0004427 (0.04) ! inorganic diphosphatase activity; GO:0000287 (0.04) ! magnesium ion binding GO:0009987 (0.59) ! cellular process; GO:0046835 (0.57) ! carbohydrate phosphorylation; GO:0006810 (0.46) ! transport; GO:0044351 (0.43) ! macropinocytosis; GO:0035725 (0.05) ! sodium ion transmembrane transport; GO:0015992 (0.05) ! proton transport GO:0043227 (0.61) ! membrane-bounded organelle; GO:0044464 (0.52) ! cell part; GO:0070062 (0.51) ! extracellular exosome; GO:0044424 (0.44) ! intracellular part; GO:0016020 (0.41) ! membrane; GO:0044444 (0.34) ! cytoplasmic part; GO:0044446 (0.26) ! intracellular organelle part; GO:0031090 (0.25) ! organelle membrane; GO:0005743 (0.24) ! mitochondrial inner membrane; GO:0016021 (0.23) ! integral component of membrane; GO:0043231 (0.10) ! intracellular membrane-bounded organelle; GO:0005737 (0.10) ! cytoplasm; GO:0005783 (0.08) ! endoplasmic reticulum; GO:0005886 (0.04) ! plasma membrane; GO:0044437 (0.03) ! vacuolar part; GO:0005887 (0.03) ! integral component of plasma membrane; GO:0005773 (0.03) ! vacuole; GO:0005576 (0.03) ! extracellular region; GO:0044162 (0.01) ! host cell cytoplasmic vesicle membrane; GO:0044161 (0.01) ! host cell cytoplasmic vesicle; GO:0043202 (0.01) ! lysosomal lumen; GO:0034364 (0.01) ! high-density lipoprotein particle; GO:0009279 (0.01) ! cell outer membrane; GO:0005774 (0.01) ! vacuolar membrane; GO:0005764 (0.01) ! lysosome; GO:0005622 (0.01) ! intracellular; GO:0005615 (0.01) ! extracellular space GO:0070062 ! extracellular exosome GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 2 7402975-7404137 (17p13.1) Cells - EBV-transformed lymphocytes: 125.35; Nerve - Tibial: 114.20; Cervix - Endocervix: 101.50; Cervix - Ectocervix: 98.81; Ovary: 92.08; Fallopian Tube: 88.67; Prostate: 86.75; Breast - Mammary Tissue: 85.71; Adipose - Visceral (Omentum): 83.41; Cells - Transformed fibroblasts: 83.03; Uterus: 82.64; Small Intestine - Terminal Ileum: 81.49; Brain - Spinal cord (cervical c-1): 80.98; Adipose - Subcutaneous: 77.24; Bladder: 75.93; Vagina: 74.54; Artery - Coronary: 71.48; Stomach: 68.31; Adrenal Gland: 68.28; Spleen: 67.69; Liver: 67.41; Thyroid: 64.81; Esophagus - Gastroesophageal Junction: 63.55; Colon - Sigmoid: 63.34; Artery - Aorta: 63.07; Kidney - Cortex: 63.00; Colon - Transverse: 61.34; Lung: 61.31; Esophagus - Mucosa: 60.46; Artery - Tibial: 59.78; Skin - Not Sun Exposed (Suprapubic): 58.70; Esophagus - Muscularis: 57.78; Minor Salivary Gland: 53.10; Brain - Substantia nigra: 52.04; Pituitary: 51.26; Heart - Atrial Appendage: 50.73; Skin - Sun Exposed (Lower leg): 50.32; Pancreas: 45.33; Brain - Frontal Cortex (BA9): 39.32; Brain - Amygdala: 38.91; Brain - Anterior cingulate cortex (BA24): 38.31; Brain - Hippocampus: 37.89; Brain - Nucleus accumbens (basal ganglia): 36.63; Brain - Hypothalamus: 36.63; Brain - Cerebellar Hemisphere: 35.70; Brain - Caudate (basal ganglia): 34.95; Brain - Cerebellum: 33.35; Brain - Cortex: 33.01; Brain - Putamen (basal ganglia): 32.99; Heart - Left Ventricle: 30.76; Muscle - Skeletal: 26.04; Testis: 17.31; Whole Blood: 13.33; MAGPAAAFRRLGALSGAAALGFASYGAHGAQFPDAYGKELFDKANKHHFLHSLALLGVPHCRKPLWAGLLLASGTTLFCTSFYYQALSGDPSIQTLAPAGGTLLLLGWLALAL SPEM2 Uncharacterized protein SPEM2 SPEM2_HUMAN (Q0P670-1) GO:0003824 (0.43) ! catalytic activity; GO:0005215 (0.25) ! transporter activity; GO:0022892 (0.24) ! substrate-specific transporter activity; GO:0008324 (0.23) ! cation transmembrane transporter activity; GO:0005261 (0.21) ! cation channel activity; GO:0046873 (0.19) ! metal ion transmembrane transporter activity; GO:0022836 (0.18) ! gated channel activity; GO:0022843 (0.17) ! voltage-gated cation channel activity; GO:0005245 (0.16) ! voltage-gated calcium channel activity; GO:0016740 (0.13) ! transferase activity; GO:1901363 (0.11) ! heterocyclic compound binding; GO:0097159 (0.11) ! organic cyclic compound binding; GO:0016772 (0.11) ! transferase activity, transferring phosphorus-containing groups; GO:0019899 (0.10) ! enzyme binding; GO:0003676 (0.10) ! nucleic acid binding; GO:0008332 (0.09) ! low voltage-gated calcium channel activity; GO:0097110 (0.07) ! scaffold protein binding; GO:0005198 (0.07) ! structural molecule activity; GO:0004672 (0.07) ! protein kinase activity; GO:0030234 (0.06) ! enzyme regulator activity; GO:0017016 (0.06) ! Ras GTPase binding; GO:0016787 (0.06) ! hydrolase activity; GO:0008331 (0.06) ! high voltage-gated calcium channel activity; GO:0044877 (0.05) ! macromolecular complex binding; GO:0005096 (0.05) ! GTPase activator activity; GO:0004674 (0.05) ! protein serine/threonine kinase activity; GO:0003723 (0.05) ! RNA binding; GO:0003712 (0.05) ! transcription cofactor activity; GO:0044822 (0.04) ! poly(A) RNA binding; GO:0043169 (0.04) ! cation binding; GO:0017137 (0.04) ! Rab GTPase binding; GO:0005201 (0.04) ! extracellular matrix structural constituent; GO:0005102 (0.04) ! receptor binding; GO:0004872 (0.04) ! receptor activity; GO:0004871 (0.04) ! signal transducer activity; GO:0003677 (0.04) ! DNA binding; GO:0001104 (0.04) ! RNA polymerase II transcription cofactor activity; GO:0001055 (0.04) ! RNA polymerase II activity; GO:0099600 (0.03) ! transmembrane receptor activity; GO:0046872 (0.03) ! metal ion binding; GO:0044212 (0.03) ! transcription regulatory region DNA binding; GO:0032403 (0.03) ! protein complex binding; GO:0019900 (0.03) ! kinase binding; GO:0016788 (0.03) ! hydrolase activity, acting on ester bonds; GO:0015077 (0.03) ! monovalent inorganic cation transmembrane transporter activity; GO:0008092 (0.03) ! cytoskeletal protein binding; GO:0005543 (0.03) ! phospholipid binding; GO:0003682 (0.03) ! chromatin binding; GO:0050839 (0.02) ! cell adhesion molecule binding; GO:0043565 (0.02) ! sequence-specific DNA binding; GO:0030507 (0.02) ! spectrin binding; GO:0019905 (0.02) ! syntaxin binding; GO:0019904 (0.02) ! protein domain specific binding; GO:0019901 (0.02) ! protein kinase binding; GO:0016887 (0.02) ! ATPase activity; GO:0008093 (0.02) ! cytoskeletal adaptor activity; GO:0005544 (0.02) ! calcium-dependent phospholipid binding; GO:0005522 (0.02) ! profilin binding; GO:0005509 (0.02) ! calcium ion binding; GO:0005487 (0.02) ! nucleocytoplasmic transporter activity; GO:0004888 (0.02) ! transmembrane signaling receptor activity; GO:0004715 (0.02) ! non-membrane spanning protein tyrosine kinase activity; GO:0003700 (0.02) ! transcription factor activity, sequence-specific DNA binding; GO:0003690 (0.02) ! double-stranded DNA binding; GO:1990841 (0.01) ! promoter-specific chromatin binding; GO:0098641 (0.01) ! cadherin binding involved in cell-cell adhesion; GO:0086059 (0.01) ! voltage-gated calcium channel activity involved SA node cell action potential; GO:0086056 (0.01) ! voltage-gated calcium channel activity involved in AV node cell action potential; GO:0070300 (0.01) ! phosphatidic acid binding; GO:0070097 (0.01) ! delta-catenin binding; GO:0070064 (0.01) ! proline-rich region binding; GO:0070011 (0.01) ! peptidase activity, acting on L-amino acid peptides; GO:0061630 (0.01) ! ubiquitin protein ligase activity; GO:0052689 (0.01) ! carboxylic ester hydrolase activity; GO:0051019 (0.01) ! mitogen-activated protein kinase binding; GO:0051015 (0.01) ! actin filament binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0043621 (0.01) ! protein self-association; GO:0042802 (0.01) ! identical protein binding; GO:0042800 (0.01) ! histone methyltransferase activity (H3-K4 specific); GO:0042166 (0.01) ! acetylcholine binding; GO:0042043 (0.01) ! neurexin family protein binding; GO:0034595 (0.01) ! phosphatidylinositol phosphate 5-phosphatase activity; GO:0032184 (0.01) ! SUMO polymer binding; GO:0031491 (0.01) ! nucleosome binding; GO:0030165 (0.01) ! PDZ domain binding; GO:0030145 (0.01) ! manganese ion binding; GO:0017124 (0.01) ! SH3 domain binding; GO:0017056 (0.01) ! structural constituent of nuclear pore; GO:0017049 (0.01) ! GTP-Rho binding; GO:0015464 (0.01) ! acetylcholine receptor activity; GO:0008536 (0.01) ! Ran GTPase binding; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008201 (0.01) ! heparin binding; GO:0008139 (0.01) ! nuclear localization sequence binding; GO:0008134 (0.01) ! transcription factor binding; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005546 (0.01) ! phosphatidylinositol-4,5-bisphosphate binding; GO:0005524 (0.01) ! ATP binding; GO:0005328 (0.01) ! neurotransmitter:sodium symporter activity; GO:0005249 (0.01) ! voltage-gated potassium channel activity; GO:0005080 (0.01) ! protein kinase C binding; GO:0005049 (0.01) ! nuclear export signal receptor activity; GO:0004930 (0.01) ! G-protein coupled receptor activity; GO:0004889 (0.01) ! acetylcholine-activated cation-selective channel activity; GO:0004857 (0.01) ! enzyme inhibitor activity; GO:0004702 (0.01) ! receptor signaling protein serine/threonine kinase activity; GO:0004620 (0.01) ! phospholipase activity; GO:0004407 (0.01) ! histone deacetylase activity; GO:0004004 (0.01) ! ATP-dependent RNA helicase activity; GO:0003777 (0.01) ! microtubule motor activity; GO:0003713 (0.01) ! transcription coactivator activity; GO:0001106 (0.01) ! RNA polymerase II transcription corepressor activity; GO:0000981 (0.01) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0000978 (0.01) ! RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0000287 (0.01) ! magnesium ion binding GO:0009987 (0.72) ! cellular process; GO:0044699 (0.62) ! single-organism process; GO:0065007 (0.57) ! biological regulation; GO:0044763 (0.54) ! single-organism cellular process; GO:0050789 (0.48) ! regulation of biological process; GO:0050794 (0.47) ! regulation of cellular process; GO:0044767 (0.36) ! single-organism developmental process; GO:0051179 (0.29) ! localization; GO:0065008 (0.28) ! regulation of biological quality; GO:0006810 (0.28) ! transport; GO:0016043 (0.23) ! cellular component organization; GO:0008152 (0.22) ! metabolic process; GO:0071704 (0.21) ! organic substance metabolic process; GO:0044238 (0.21) ! primary metabolic process; GO:0044237 (0.21) ! cellular metabolic process; GO:0050896 (0.20) ! response to stimulus; GO:0044260 (0.20) ! cellular macromolecule metabolic process; GO:0032501 (0.20) ! multicellular organismal process; GO:0007165 (0.19) ! signal transduction; GO:0048522 (0.18) ! positive regulation of cellular process; GO:0044707 (0.18) ! single-multicellular organism process; GO:0042391 (0.18) ! regulation of membrane potential; GO:0022414 (0.18) ! reproductive process; GO:0044702 (0.17) ! single organism reproductive process; GO:0040011 (0.17) ! locomotion; GO:0019222 (0.17) ! regulation of metabolic process; GO:0006928 (0.17) ! movement of cell or subcellular component; GO:0048646 (0.16) ! anatomical structure formation involved in morphogenesis; GO:0031323 (0.16) ! regulation of cellular metabolic process; GO:0007276 (0.16) ! gamete generation; GO:0003006 (0.16) ! developmental process involved in reproduction; GO:0080090 (0.15) ! regulation of primary metabolic process; GO:0060255 (0.15) ! regulation of macromolecule metabolic process; GO:0048856 (0.15) ! anatomical structure development; GO:0030317 (0.15) ! sperm motility; GO:0007291 (0.15) ! sperm individualization; GO:0007283 (0.15) ! spermatogenesis; GO:0051641 (0.14) ! cellular localization; GO:0032879 (0.14) ! regulation of localization; GO:0010468 (0.14) ! regulation of gene expression; GO:0007267 (0.14) ! cell-cell signaling; GO:2000112 (0.13) ! regulation of cellular macromolecule biosynthetic process; GO:1901360 (0.13) ! organic cyclic compound metabolic process; GO:0051239 (0.13) ! regulation of multicellular organismal process; GO:0051049 (0.13) ! regulation of transport; GO:0034641 (0.13) ! cellular nitrogen compound metabolic process; GO:0019219 (0.13) ! regulation of nucleobase-containing compound metabolic process; GO:0006812 (0.13) ! cation transport; GO:0090304 (0.12) ! nucleic acid metabolic process; GO:0051716 (0.12) ! cellular response to stimulus; GO:0051649 (0.12) ! establishment of localization in cell; GO:0048519 (0.12) ! negative regulation of biological process; GO:0042221 (0.12) ! response to chemical; GO:0008104 (0.12) ! protein localization; GO:0006816 (0.12) ! calcium ion transport; GO:0006355 (0.12) ! regulation of transcription, DNA-templated; GO:0009892 (0.11) ! negative regulation of metabolic process; GO:0006996 (0.11) ! organelle organization; GO:0006950 (0.11) ! response to stress; GO:1903522 (0.10) ! regulation of blood circulation; GO:0086010 (0.10) ! membrane depolarization during action potential; GO:0046907 (0.10) ! intracellular transport; GO:0033554 (0.10) ! cellular response to stress; GO:0031325 (0.10) ! positive regulation of cellular metabolic process; GO:0022607 (0.10) ! cellular component assembly; GO:0016070 (0.10) ! RNA metabolic process; GO:0010604 (0.10) ! positive regulation of macromolecule metabolic process; GO:0009653 (0.10) ! anatomical structure morphogenesis; GO:2000021 (0.09) ! regulation of ion homeostasis; GO:0071702 (0.09) ! organic substance transport; GO:0060627 (0.09) ! regulation of vesicle-mediated transport; GO:0051173 (0.09) ! positive regulation of nitrogen compound metabolic process; GO:0051128 (0.09) ! regulation of cellular component organization; GO:0048869 (0.09) ! cellular developmental process; GO:0045184 (0.09) ! establishment of protein localization; GO:0044249 (0.09) ! cellular biosynthetic process; GO:0031328 (0.09) ! positive regulation of cellular biosynthetic process; GO:0019538 (0.09) ! protein metabolic process; GO:0010628 (0.09) ! positive regulation of gene expression; GO:0010605 (0.09) ! negative regulation of macromolecule metabolic process; GO:0010557 (0.09) ! positive regulation of macromolecule biosynthetic process; GO:0009059 (0.09) ! macromolecule biosynthetic process; GO:0008016 (0.09) ! regulation of heart contraction; GO:0007268 (0.09) ! chemical synaptic transmission; GO:1902680 (0.08) ! positive regulation of RNA biosynthetic process; GO:0070509 (0.08) ! calcium ion import; GO:0043933 (0.08) ! macromolecular complex subunit organization; GO:0034654 (0.08) ! nucleobase-containing compound biosynthetic process; GO:0034645 (0.08) ! cellular macromolecule biosynthetic process; GO:0023051 (0.08) ! regulation of signaling; GO:0016192 (0.08) ! vesicle-mediated transport; GO:0010646 (0.08) ! regulation of cell communication; GO:0010629 (0.08) ! negative regulation of gene expression; GO:0010035 (0.08) ! response to inorganic substance; GO:0007166 (0.08) ! cell surface receptor signaling pathway; GO:0006974 (0.08) ! cellular response to DNA damage stimulus; GO:0006886 (0.08) ! intracellular protein transport; GO:0006464 (0.08) ! cellular protein modification process; GO:0006259 (0.08) ! DNA metabolic process; GO:0002027 (0.08) ! regulation of heart rate; GO:0001508 (0.08) ! action potential; GO:1903530 (0.07) ! regulation of secretion by cell; GO:0060371 (0.07) ! regulation of atrial cardiac muscle cell membrane depolarization; GO:0048523 (0.07) ! negative regulation of cellular process; GO:0044710 (0.07) ! single-organism metabolic process; GO:0032774 (0.07) ! RNA biosynthetic process; GO:0010045 (0.07) ! response to nickel cation; GO:0007167 (0.07) ! enzyme linked receptor protein signaling pathway; GO:0007010 (0.07) ! cytoskeleton organization; GO:0006281 (0.07) ! DNA repair; GO:0000398 (0.07) ! mRNA splicing, via spliceosome; GO:0090066 (0.06) ! regulation of anatomical structure size; GO:0065003 (0.06) ! macromolecular complex assembly; GO:0051050 (0.06) ! positive regulation of transport; GO:0050790 (0.06) ! regulation of catalytic activity; GO:0048731 (0.06) ! system development; GO:0046782 (0.06) ! regulation of viral transcription; GO:0044711 (0.06) ! single-organism biosynthetic process; GO:0035556 (0.06) ! intracellular signal transduction; GO:0034660 (0.06) ! ncRNA metabolic process; GO:0034613 (0.06) ! cellular protein localization; GO:0031324 (0.06) ! negative regulation of cellular metabolic process; GO:0019827 (0.06) ! stem cell population maintenance; GO:0016458 (0.06) ! gene silencing; GO:0007169 (0.06) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0006368 (0.06) ! transcription elongation from RNA polymerase II promoter; GO:0006367 (0.06) ! transcription initiation from RNA polymerase II promoter; GO:0006366 (0.06) ! transcription from RNA polymerase II promoter; GO:0006357 (0.06) ! regulation of transcription from RNA polymerase II promoter; GO:0003008 (0.06) ! system process; GO:1903532 (0.05) ! positive regulation of secretion by cell; GO:0071822 (0.05) ! protein complex subunit organization; GO:0055114 (0.05) ! oxidation-reduction process; GO:0051336 (0.05) ! regulation of hydrolase activity; GO:0050877 (0.05) ! neurological system process; GO:0050793 (0.05) ! regulation of developmental process; GO:0050434 (0.05) ! positive regulation of viral transcription; GO:0048583 (0.05) ! regulation of response to stimulus; GO:0048513 (0.05) ! animal organ development; GO:0044093 (0.05) ! positive regulation of molecular function; GO:0042795 (0.05) ! snRNA transcription from RNA polymerase II promoter; GO:0035019 (0.05) ! somatic stem cell population maintenance; GO:0033120 (0.05) ! positive regulation of RNA splicing; GO:0033068 (0.05) ! macrolide biosynthetic process; GO:0033043 (0.05) ! regulation of organelle organization; GO:0031047 (0.05) ! gene silencing by RNA; GO:0017158 (0.05) ! regulation of calcium ion-dependent exocytosis; GO:0008543 (0.05) ! fibroblast growth factor receptor signaling pathway; GO:0007610 (0.05) ! behavior; GO:0006468 (0.05) ! protein phosphorylation; GO:0006457 (0.05) ! protein folding; GO:0006370 (0.05) ! 7-methylguanosine mRNA capping; GO:0006353 (0.05) ! DNA-templated transcription, termination; GO:0006283 (0.05) ! transcription-coupled nucleotide-excision repair; GO:0001172 (0.05) ! transcription, RNA-templated; GO:1902589 (0.04) ! single-organism organelle organization; GO:1902580 (0.04) ! single-organism cellular localization; GO:0090630 (0.04) ! activation of GTPase activity; GO:0050767 (0.04) ! regulation of neurogenesis; GO:0048193 (0.04) ! Golgi vesicle transport; GO:0046331 (0.04) ! lateral inhibition; GO:0045956 (0.04) ! positive regulation of calcium ion-dependent exocytosis; GO:0044719 (0.04) ! regulation of imaginal disc-derived wing size; GO:0043009 (0.04) ! chordate embryonic development; GO:0042127 (0.04) ! regulation of cell proliferation; GO:0040005 (0.04) ! chitin-based cuticle attachment to epithelium; GO:0034220 (0.04) ! ion transmembrane transport; GO:0033365 (0.04) ! protein localization to organelle; GO:0031344 (0.04) ! regulation of cell projection organization; GO:0031338 (0.04) ! regulation of vesicle fusion; GO:0031327 (0.04) ! negative regulation of cellular biosynthetic process; GO:0030518 (0.04) ! intracellular steroid hormone receptor signaling pathway; GO:0018193 (0.04) ! peptidyl-amino acid modification; GO:0010033 (0.04) ! response to organic substance; GO:0008362 (0.04) ! chitin-based embryonic cuticle biosynthetic process; GO:0007475 (0.04) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.04) ! open tracheal system development; GO:0006461 (0.04) ! protein complex assembly; GO:0006325 (0.04) ! chromatin organization; GO:0002376 (0.04) ! immune system process; GO:1902582 (0.03) ! single-organism intracellular transport; GO:0070887 (0.03) ! cellular response to chemical stimulus; GO:0051240 (0.03) ! positive regulation of multicellular organismal process; GO:0051094 (0.03) ! positive regulation of developmental process; GO:0050890 (0.03) ! cognition; GO:0048589 (0.03) ! developmental growth; GO:0048584 (0.03) ! positive regulation of response to stimulus; GO:0048468 (0.03) ! cell development; GO:0045944 (0.03) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045892 (0.03) ! negative regulation of transcription, DNA-templated; GO:0045664 (0.03) ! regulation of neuron differentiation; GO:0044802 (0.03) ! single-organism membrane organization; GO:0043065 (0.03) ! positive regulation of apoptotic process; GO:0034622 (0.03) ! cellular macromolecular complex assembly; GO:0032940 (0.03) ! secretion by cell; GO:0032268 (0.03) ! regulation of cellular protein metabolic process; GO:0030154 (0.03) ! cell differentiation; GO:0030030 (0.03) ! cell projection organization; GO:0019220 (0.03) ! regulation of phosphate metabolic process; GO:0016337 (0.03) ! single organismal cell-cell adhesion; GO:0016049 (0.03) ! cell growth; GO:0009966 (0.03) ! regulation of signal transduction; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0008284 (0.03) ! positive regulation of cell proliferation; GO:0007626 (0.03) ! locomotory behavior; GO:0007017 (0.03) ! microtubule-based process; GO:0006874 (0.03) ! cellular calcium ion homeostasis; GO:0003013 (0.03) ! circulatory system process; GO:1904062 (0.02) ! regulation of cation transmembrane transport; GO:1903053 (0.02) ! regulation of extracellular matrix organization; GO:1903047 (0.02) ! mitotic cell cycle process; GO:1902531 (0.02) ! regulation of intracellular signal transduction; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:1901216 (0.02) ! positive regulation of neuron death; GO:0099531 (0.02) ! presynaptic process involved in chemical synaptic transmission; GO:0098910 (0.02) ! regulation of atrial cardiac muscle cell action potential; GO:0098876 (0.02) ! vesicle-mediated transport to the plasma membrane; GO:0090276 (0.02) ! regulation of peptide hormone secretion; GO:0080135 (0.02) ! regulation of cellular response to stress; GO:0072661 (0.02) ! protein targeting to plasma membrane; GO:0071705 (0.02) ! nitrogen compound transport; GO:0071495 (0.02) ! cellular response to endogenous stimulus; GO:0071310 (0.02) ! cellular response to organic substance; GO:0060560 (0.02) ! developmental growth involved in morphogenesis; GO:0060341 (0.02) ! regulation of cellular localization; GO:0051924 (0.02) ! regulation of calcium ion transport; GO:0051223 (0.02) ! regulation of protein transport; GO:0051130 (0.02) ! positive regulation of cellular component organization; GO:0050880 (0.02) ! regulation of blood vessel size; GO:0050769 (0.02) ! positive regulation of neurogenesis; GO:0048729 (0.02) ! tissue morphogenesis; GO:0048588 (0.02) ! developmental cell growth; GO:0048146 (0.02) ! positive regulation of fibroblast proliferation; GO:0046777 (0.02) ! protein autophosphorylation; GO:0044708 (0.02) ! single-organism behavior; GO:0044087 (0.02) ! regulation of cellular component biogenesis; GO:0043623 (0.02) ! cellular protein complex assembly; GO:0043414 (0.02) ! macromolecule methylation; GO:0043086 (0.02) ! negative regulation of catalytic activity; GO:0042493 (0.02) ! response to drug; GO:0042472 (0.02) ! inner ear morphogenesis; GO:0042110 (0.02) ! T cell activation; GO:0035637 (0.02) ! multicellular organismal signaling; GO:0034599 (0.02) ! cellular response to oxidative stress; GO:0033993 (0.02) ! response to lipid; GO:0032270 (0.02) ! positive regulation of cellular protein metabolic process; GO:0031503 (0.02) ! protein complex localization; GO:0030036 (0.02) ! actin cytoskeleton organization; GO:0023061 (0.02) ! signal release; GO:0018105 (0.02) ! peptidyl-serine phosphorylation; GO:0016570 (0.02) ! histone modification; GO:0016197 (0.02) ! endosomal transport; GO:0014070 (0.02) ! response to organic cyclic compound; GO:0010975 (0.02) ! regulation of neuron projection development; GO:0010769 (0.02) ! regulation of cell morphogenesis involved in differentiation; GO:0010243 (0.02) ! response to organonitrogen compound; GO:0009967 (0.02) ! positive regulation of signal transduction; GO:0008219 (0.02) ! cell death; GO:0007600 (0.02) ! sensory perception; GO:0007274 (0.02) ! neuromuscular synaptic transmission; GO:0007204 (0.02) ! positive regulation of cytosolic calcium ion concentration; GO:0007018 (0.02) ! microtubule-based movement; GO:0007015 (0.02) ! actin filament organization; GO:0006955 (0.02) ! immune response; GO:0006897 (0.02) ! endocytosis; GO:0006892 (0.02) ! post-Golgi vesicle-mediated transport; GO:0006888 (0.02) ! ER to Golgi vesicle-mediated transport; GO:0006887 (0.02) ! exocytosis; GO:0006836 (0.02) ! neurotransmitter transport; GO:0001932 (0.02) ! regulation of protein phosphorylation; GO:0001701 (0.02) ! in utero embryonic development; GO:0000902 (0.02) ! cell morphogenesis; GO:0000226 (0.02) ! microtubule cytoskeleton organization; GO:0000122 (0.02) ! negative regulation of transcription from RNA polymerase II promoter; GO:2001020 (0.01) ! regulation of response to DNA damage stimulus; GO:2000773 (0.01) ! negative regulation of cellular senescence; GO:2000352 (0.01) ! negative regulation of endothelial cell apoptotic process; GO:2000096 (0.01) ! positive regulation of Wnt signaling pathway, planar cell polarity pathway; GO:1990126 (0.01) ! retrograde transport, endosome to plasma membrane; GO:1990051 (0.01) ! activation of protein kinase C activity; GO:1904531 (0.01) ! positive regulation of actin filament binding; GO:1904528 (0.01) ! positive regulation of microtubule binding; GO:1903358 (0.01) ! regulation of Golgi organization; GO:1903210 (0.01) ! glomerular visceral epithelial cell apoptotic process; GO:1903055 (0.01) ! positive regulation of extracellular matrix organization; GO:1902715 (0.01) ! positive regulation of interferon-gamma secretion; GO:1902017 (0.01) ! regulation of cilium assembly; GO:1901566 (0.01) ! organonitrogen compound biosynthetic process; GO:1901361 (0.01) ! organic cyclic compound catabolic process; GO:1901300 (0.01) ! positive regulation of hydrogen peroxide-mediated programmed cell death; GO:1900364 (0.01) ! negative regulation of mRNA polyadenylation; GO:1900275 (0.01) ! negative regulation of phospholipase C activity; GO:1900042 (0.01) ! positive regulation of interleukin-2 secretion; GO:1900006 (0.01) ! positive regulation of dendrite development; GO:0098655 (0.01) ! cation transmembrane transport; GO:0097320 (0.01) ! membrane tubulation; GO:0097190 (0.01) ! apoptotic signaling pathway; GO:0090135 (0.01) ! actin filament branching; GO:0086091 (0.01) ! regulation of heart rate by cardiac conduction; GO:0086046 (0.01) ! membrane depolarization during SA node cell action potential; GO:0086045 (0.01) ! membrane depolarization during AV node cell action potential; GO:0086027 (0.01) ! AV node cell to bundle of His cell signaling; GO:0086018 (0.01) ! SA node cell to atrial cardiac muscle cell signalling; GO:0086016 (0.01) ! AV node cell action potential; GO:0086015 (0.01) ! SA node cell action potential; GO:0072358 (0.01) ! cardiovascular system development; GO:0071901 (0.01) ! negative regulation of protein serine/threonine kinase activity; GO:0071871 (0.01) ! response to epinephrine; GO:0071560 (0.01) ! cellular response to transforming growth factor beta stimulus; GO:0071385 (0.01) ! cellular response to glucocorticoid stimulus; GO:0071222 (0.01) ! cellular response to lipopolysaccharide; GO:0071214 (0.01) ! cellular response to abiotic stimulus; GO:0070972 (0.01) ! protein localization to endoplasmic reticulum; GO:0070374 (0.01) ! positive regulation of ERK1 and ERK2 cascade; GO:0070373 (0.01) ! negative regulation of ERK1 and ERK2 cascade; GO:0070301 (0.01) ! cellular response to hydrogen peroxide; GO:0061029 (0.01) ! eyelid development in camera-type eye; GO:0060429 (0.01) ! epithelium development; GO:0060411 (0.01) ! cardiac septum morphogenesis; GO:0060402 (0.01) ! calcium ion transport into cytosol; GO:0060384 (0.01) ! innervation; GO:0060324 (0.01) ! face development; GO:0060173 (0.01) ! limb development; GO:0060123 (0.01) ! regulation of growth hormone secretion; GO:0060047 (0.01) ! heart contraction; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0060026 (0.01) ! convergent extension; GO:0060021 (0.01) ! palate development; GO:0060020 (0.01) ! Bergmann glial cell differentiation; GO:0055013 (0.01) ! cardiac muscle cell development; GO:0051952 (0.01) ! regulation of amine transport; GO:0051601 (0.01) ! exocyst localization; GO:0051568 (0.01) ! histone H3-K4 methylation; GO:0051444 (0.01) ! negative regulation of ubiquitin-protein transferase activity; GO:0051353 (0.01) ! positive regulation of oxidoreductase activity; GO:0051315 (0.01) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051281 (0.01) ! positive regulation of release of sequestered calcium ion into cytosol; GO:0051260 (0.01) ! protein homooligomerization; GO:0051149 (0.01) ! positive regulation of muscle cell differentiation; GO:0051056 (0.01) ! regulation of small GTPase mediated signal transduction; GO:0050982 (0.01) ! detection of mechanical stimulus; GO:0050885 (0.01) ! neuromuscular process controlling balance; GO:0050853 (0.01) ! B cell receptor signaling pathway; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0050798 (0.01) ! activated T cell proliferation; GO:0050796 (0.01) ! regulation of insulin secretion; GO:0050731 (0.01) ! positive regulation of peptidyl-tyrosine phosphorylation; GO:0048858 (0.01) ! cell projection morphogenesis; GO:0048793 (0.01) ! pronephros development; GO:0048752 (0.01) ! semicircular canal morphogenesis; GO:0048738 (0.01) ! cardiac muscle tissue development; GO:0048675 (0.01) ! axon extension; GO:0048668 (0.01) ! collateral sprouting; GO:0048538 (0.01) ! thymus development; GO:0048536 (0.01) ! spleen development; GO:0048477 (0.01) ! oogenesis; GO:0048259 (0.01) ! regulation of receptor-mediated endocytosis; GO:0048227 (0.01) ! plasma membrane to endosome transport; GO:0048208 (0.01) ! COPII vesicle coating; GO:0046632 (0.01) ! alpha-beta T cell differentiation; GO:0046486 (0.01) ! glycerolipid metabolic process; GO:0045931 (0.01) ! positive regulation of mitotic cell cycle; GO:0045930 (0.01) ! negative regulation of mitotic cell cycle; GO:0045907 (0.01) ! positive regulation of vasoconstriction; GO:0045214 (0.01) ! sarcomere organization; GO:0045087 (0.01) ! innate immune response; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0043627 (0.01) ! response to estrogen; GO:0043584 (0.01) ! nose development; GO:0043525 (0.01) ! positive regulation of neuron apoptotic process; GO:0043161 (0.01) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043124 (0.01) ! negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043123 (0.01) ! positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043010 (0.01) ! camera-type eye development; GO:0042770 (0.01) ! signal transduction in response to DNA damage; GO:0042471 (0.01) ! ear morphogenesis; GO:0042384 (0.01) ! cilium assembly; GO:0042048 (0.01) ! olfactory behavior; GO:0040018 (0.01) ! positive regulation of multicellular organism growth; GO:0038083 (0.01) ! peptidyl-tyrosine autophosphorylation; GO:0036302 (0.01) ! atrioventricular canal development; GO:0036269 (0.01) ! swimming behavior; GO:0036010 (0.01) ! protein localization to endosome; GO:0035909 (0.01) ! aorta morphogenesis; GO:0035904 (0.01) ! aorta development; GO:0035791 (0.01) ! platelet-derived growth factor receptor-beta signaling pathway; GO:0035690 (0.01) ! cellular response to drug; GO:0035526 (0.01) ! retrograde transport, plasma membrane to Golgi; GO:0035418 (0.01) ! protein localization to synapse; GO:0035372 (0.01) ! protein localization to microtubule; GO:0035264 (0.01) ! multicellular organism growth; GO:0035116 (0.01) ! embryonic hindlimb morphogenesis; GO:0035095 (0.01) ! behavioral response to nicotine; GO:0035094 (0.01) ! response to nicotine; GO:0034976 (0.01) ! response to endoplasmic reticulum stress; GO:0034501 (0.01) ! protein localization to kinetochore; GO:0034446 (0.01) ! substrate adhesion-dependent cell spreading; GO:0033690 (0.01) ! positive regulation of osteoblast proliferation; GO:0033234 (0.01) ! negative regulation of protein sumoylation; GO:0033148 (0.01) ! positive regulation of intracellular estrogen receptor signaling pathway; GO:0032956 (0.01) ! regulation of actin cytoskeleton organization; GO:0032786 (0.01) ! positive regulation of DNA-templated transcription, elongation; GO:0032785 (0.01) ! negative regulation of DNA-templated transcription, elongation; GO:0032458 (0.01) ! slow endocytic recycling; GO:0032414 (0.01) ! positive regulation of ion transmembrane transporter activity; GO:0032353 (0.01) ! negative regulation of hormone biosynthetic process; GO:0031648 (0.01) ! protein destabilization; GO:0031505 (0.01) ! fungal-type cell wall organization; GO:0031497 (0.01) ! chromatin assembly; GO:0031175 (0.01) ! neuron projection development; GO:0031134 (0.01) ! sister chromatid biorientation; GO:0031113 (0.01) ! regulation of microtubule polymerization; GO:0031098 (0.01) ! stress-activated protein kinase signaling cascade; GO:0030705 (0.01) ! cytoskeleton-dependent intracellular transport; GO:0030540 (0.01) ! female genitalia development; GO:0030521 (0.01) ! androgen receptor signaling pathway; GO:0030516 (0.01) ! regulation of axon extension; GO:0030514 (0.01) ! negative regulation of BMP signaling pathway; GO:0030097 (0.01) ! hemopoiesis; GO:0030073 (0.01) ! insulin secretion; GO:0030041 (0.01) ! actin filament polymerization; GO:0030035 (0.01) ! microspike assembly; GO:0022408 (0.01) ! negative regulation of cell-cell adhesion; GO:0021772 (0.01) ! olfactory bulb development; GO:0021587 (0.01) ! cerebellum morphogenesis; GO:0021553 (0.01) ! olfactory nerve development; GO:0019933 (0.01) ! cAMP-mediated signaling; GO:0019886 (0.01) ! antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0019722 (0.01) ! calcium-mediated signaling; GO:0019233 (0.01) ! sensory perception of pain; GO:0019068 (0.01) ! virion assembly; GO:0016575 (0.01) ! histone deacetylation; GO:0016567 (0.01) ! protein ubiquitination; GO:0016477 (0.01) ! cell migration; GO:0016239 (0.01) ! positive regulation of macroautophagy; GO:0016080 (0.01) ! synaptic vesicle targeting; GO:0016079 (0.01) ! synaptic vesicle exocytosis; GO:0010923 (0.01) ! negative regulation of phosphatase activity; GO:0010880 (0.01) ! regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:0010564 (0.01) ! regulation of cell cycle process; GO:0008306 (0.01) ! associative learning; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008015 (0.01) ! blood circulation; GO:0007628 (0.01) ! adult walking behavior; GO:0007605 (0.01) ! sensory perception of sound; GO:0007596 (0.01) ! blood coagulation; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007517 (0.01) ! muscle organ development; GO:0007512 (0.01) ! adult heart development; GO:0007464 (0.01) ! R3/R4 cell fate commitment; GO:0007420 (0.01) ! brain development; GO:0007417 (0.01) ! central nervous system development; GO:0007416 (0.01) ! synapse assembly; GO:0007338 (0.01) ! single fertilization; GO:0007271 (0.01) ! synaptic transmission, cholinergic; GO:0007186 (0.01) ! G-protein coupled receptor signaling pathway; GO:0007173 (0.01) ! epidermal growth factor receptor signaling pathway; GO:0007158 (0.01) ! neuron cell-cell adhesion; GO:0007030 (0.01) ! Golgi organization; GO:0006975 (0.01) ! DNA damage induced protein phosphorylation; GO:0006936 (0.01) ! muscle contraction; GO:0006909 (0.01) ! phagocytosis; GO:0006898 (0.01) ! receptor-mediated endocytosis; GO:0006893 (0.01) ! Golgi to plasma membrane transport; GO:0006611 (0.01) ! protein export from nucleus; GO:0006606 (0.01) ! protein import into nucleus; GO:0006405 (0.01) ! RNA export from nucleus; GO:0006342 (0.01) ! chromatin silencing; GO:0006338 (0.01) ! chromatin remodeling; GO:0006336 (0.01) ! DNA replication-independent nucleosome assembly; GO:0006310 (0.01) ! DNA recombination; GO:0006082 (0.01) ! organic acid metabolic process; GO:0006073 (0.01) ! cellular glucan metabolic process; GO:0003226 (0.01) ! right ventricular compact myocardium morphogenesis; GO:0003222 (0.01) ! ventricular trabecula myocardium morphogenesis; GO:0003007 (0.01) ! heart morphogenesis; GO:0002474 (0.01) ! antigen processing and presentation of peptide antigen via MHC class I; GO:0002333 (0.01) ! transitional one stage B cell differentiation; GO:0002322 (0.01) ! B cell proliferation involved in immune response; GO:0002064 (0.01) ! epithelial cell development; GO:0001974 (0.01) ! blood vessel remodeling; GO:0001966 (0.01) ! thigmotaxis; GO:0001922 (0.01) ! B-1 B cell homeostasis; GO:0001666 (0.01) ! response to hypoxia; GO:0001555 (0.01) ! oocyte growth; GO:0001505 (0.01) ! regulation of neurotransmitter levels; GO:0001501 (0.01) ! skeletal system development; GO:0000278 (0.01) ! mitotic cell cycle; GO:0000245 (0.01) ! spliceosomal complex assembly GO:0044464 (1.00) ! cell part; GO:0044424 (0.95) ! intracellular part; GO:0032991 (0.58) ! macromolecular complex; GO:0043234 (0.57) ! protein complex; GO:0005737 (0.53) ! cytoplasm; GO:0043226 (0.52) ! organelle; GO:0043229 (0.49) ! intracellular organelle; GO:0044444 (0.46) ! cytoplasmic part; GO:0044422 (0.40) ! organelle part; GO:0044446 (0.39) ! intracellular organelle part; GO:0043227 (0.35) ! membrane-bounded organelle; GO:0044428 (0.31) ! nuclear part; GO:0043232 (0.31) ! intracellular non-membrane-bounded organelle; GO:0043231 (0.31) ! intracellular membrane-bounded organelle; GO:0016020 (0.31) ! membrane; GO:0005886 (0.29) ! plasma membrane; GO:0044451 (0.26) ! nucleoplasm part; GO:1902494 (0.24) ! catalytic complex; GO:1990234 (0.23) ! transferase complex; GO:0005829 (0.22) ! cytosol; GO:0061695 (0.21) ! transferase complex, transferring phosphorus-containing groups; GO:0005634 (0.21) ! nucleus; GO:0005665 (0.20) ! DNA-directed RNA polymerase II, core complex; GO:0044445 (0.17) ! cytosolic part; GO:0005654 (0.14) ! nucleoplasm; GO:0044425 (0.13) ! membrane part; GO:0044459 (0.10) ! plasma membrane part; GO:0044427 (0.10) ! chromosomal part; GO:0005856 (0.10) ! cytoskeleton; GO:0042597 (0.09) ! periplasmic space; GO:0034081 (0.09) ! polyketide synthase complex; GO:0005835 (0.09) ! fatty acid synthase complex; GO:0005832 (0.09) ! chaperonin-containing T-complex; GO:0005811 (0.09) ! lipid particle; GO:0005777 (0.09) ! peroxisome; GO:0005730 (0.09) ! nucleolus; GO:0005719 (0.09) ! nuclear euchromatin; GO:0005618 (0.09) ! cell wall; GO:0000974 (0.09) ! Prp19 complex; GO:0044421 (0.08) ! extracellular region part; GO:0097458 (0.06) ! neuron part; GO:0031982 (0.06) ! vesicle; GO:0016021 (0.06) ! integral component of membrane; GO:0098796 (0.05) ! membrane protein complex; GO:0042995 (0.05) ! cell projection; GO:0031988 (0.05) ! membrane-bounded vesicle; GO:0044430 (0.04) ! cytoskeletal part; GO:0043005 (0.04) ! neuron projection; GO:0031012 (0.04) ! extracellular matrix; GO:0012505 (0.04) ! endomembrane system; GO:0005887 (0.04) ! integral component of plasma membrane; GO:0005622 (0.04) ! intracellular; GO:0098797 (0.03) ! plasma membrane protein complex; GO:0070847 (0.03) ! core mediator complex; GO:0070062 (0.03) ! extracellular exosome; GO:0045202 (0.03) ! synapse; GO:0044463 (0.03) ! cell projection part; GO:0043025 (0.03) ! neuronal cell body; GO:0034702 (0.03) ! ion channel complex; GO:0031410 (0.03) ! cytoplasmic vesicle; GO:0031090 (0.03) ! organelle membrane; GO:0030054 (0.03) ! cell junction; GO:0016592 (0.03) ! mediator complex; GO:0098590 (0.02) ! plasma membrane region; GO:0098588 (0.02) ! bounding membrane of organelle; GO:0044666 (0.02) ! MLL3/4 complex; GO:0044456 (0.02) ! synapse part; GO:0044449 (0.02) ! contractile fiber part; GO:0044448 (0.02) ! cell cortex part; GO:0044431 (0.02) ! Golgi apparatus part; GO:0030529 (0.02) ! intracellular ribonucleoprotein complex; GO:0030426 (0.02) ! growth cone; GO:0030425 (0.02) ! dendrite; GO:0030133 (0.02) ! transport vesicle; GO:0030117 (0.02) ! membrane coat; GO:0019898 (0.02) ! extrinsic component of membrane; GO:0009986 (0.02) ! cell surface; GO:0005911 (0.02) ! cell-cell junction; GO:0005891 (0.02) ! voltage-gated calcium channel complex; GO:0005783 (0.02) ! endoplasmic reticulum; GO:1990316 (0.01) ! ATG1/ULK1 kinase complex; GO:0098858 (0.01) ! actin-based cell projection; GO:0097525 (0.01) ! spliceosomal snRNP complex; GO:0097060 (0.01) ! synaptic membrane; GO:0071013 (0.01) ! catalytic step 2 spliceosome; GO:0055038 (0.01) ! recycling endosome membrane; GO:0048788 (0.01) ! cytoskeleton of presynaptic active zone; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0045111 (0.01) ! intermediate filament cytoskeleton; GO:0044615 (0.01) ! nuclear pore nuclear basket; GO:0044613 (0.01) ! nuclear pore central transport channel; GO:0043679 (0.01) ! axon terminus; GO:0043195 (0.01) ! terminal bouton; GO:0043034 (0.01) ! costamere; GO:0033768 (0.01) ! SUMO-targeted ubiquitin ligase complex; GO:0032044 (0.01) ! DSIF complex; GO:0031430 (0.01) ! M band; GO:0031252 (0.01) ! cell leading edge; GO:0031234 (0.01) ! extrinsic component of cytoplasmic side of plasma membrane; GO:0030424 (0.01) ! axon; GO:0030134 (0.01) ! ER to Golgi transport vesicle; GO:0030127 (0.01) ! COPII vesicle coat; GO:0030018 (0.01) ! Z disc; GO:0017053 (0.01) ! transcriptional repressor complex; GO:0016323 (0.01) ! basolateral plasma membrane; GO:0016235 (0.01) ! aggresome; GO:0015629 (0.01) ! actin cytoskeleton; GO:0012507 (0.01) ! ER to Golgi transport vesicle membrane; GO:0009277 (0.01) ! fungal-type cell wall; GO:0005913 (0.01) ! cell-cell adherens junction; GO:0005892 (0.01) ! acetylcholine-gated channel complex; GO:0005871 (0.01) ! kinesin complex; GO:0005865 (0.01) ! striated muscle thin filament; GO:0005819 (0.01) ! spindle; GO:0005813 (0.01) ! centrosome; GO:0005802 (0.01) ! trans-Golgi network; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005770 (0.01) ! late endosome; GO:0005769 (0.01) ! early endosome; GO:0005739 (0.01) ! mitochondrion; GO:0005694 (0.01) ! chromosome; GO:0005684 (0.01) ! U2-type spliceosomal complex; GO:0005643 (0.01) ! nuclear pore; GO:0005615 (0.01) ! extracellular space; GO:0005576 (0.01) ! extracellular region; GO:0001726 (0.01) ! ruffle; GO:0000777 (0.01) ! condensed chromosome kinetochore; GO:0000145 (0.01) ! exocyst; GO:0000118 (0.01) ! histone deacetylase complex GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 2 7425615-7427568 (17p13.1) MENQLWHNTVRCCNQYQESPHDAEDILLLLLGLIVLVNIGINVATMMWHGLQNALDKMIDWATQKNEIQASESPPSGPPDKAQDVHIHCILDPVQVKMSRPTQYSSFSCHHFSNHHSSSLLRCVRRRRRRHRRCRRRCCNHQQRPQNYRQIPHSHSVFRNPHRSQKMSQLHRVPFFDQEDPDSYLEEEDNLPFPYPKYPRRGWGGFYQRAGLPSNVGLWGHQGGILASLPPPSLYLSPELRCMPKRVEARSELRLQSYGRHGSQSRLWGNVEAEQWASSPPPPHRLPPNPSWVPVGHSPYPSVGWMLYDSWDQRRRGTEGFERPPASVSRNARPEAQGCREHHSPQSHQQSLLGHAYGQSHRSPHPSTEPLGYSSQDPREVRRRAADWAEALPAWRPLTTSASLTVLDEASHQRTPAPSSVLVPHSSQPWPKVQAADPAPPPTMFVPLSRNPGGNANYQVYDSLELKRQVQKSRARSSSLPPASTSTLRPSLHRSQTEKLN CDRT15 CMT1A duplicated region transcript 15 protein CDRTF_HUMAN (Q96T59-1) GO:0003824 (0.69) ! catalytic activity; GO:0030234 (0.57) ! enzyme regulator activity; GO:0016887 (0.55) ! ATPase activity; GO:0003777 (0.55) ! microtubule motor activity; GO:0043178 (0.49) ! alcohol binding; GO:0032934 (0.49) ! sterol binding; GO:0015248 (0.49) ! sterol transporter activity; GO:0008047 (0.49) ! enzyme activator activity; GO:0071814 (0.40) ! protein-lipid complex binding; GO:0070405 (0.40) ! ammonium ion binding; GO:0042277 (0.40) ! peptide binding; GO:0070325 (0.30) ! lipoprotein particle receptor binding; GO:0034190 (0.30) ! apolipoprotein receptor binding; GO:0004857 (0.30) ! enzyme inhibitor activity; GO:0071889 (0.19) ! 14-3-3 protein binding; GO:0019901 (0.19) ! protein kinase binding; GO:0030695 (0.16) ! GTPase regulator activity; GO:0004702 (0.14) ! receptor signaling protein serine/threonine kinase activity GO:0009987 (0.87) ! cellular process; GO:0044699 (0.83) ! single-organism process; GO:0044763 (0.79) ! single-organism cellular process; GO:0006810 (0.68) ! transport; GO:0050794 (0.64) ! regulation of cellular process; GO:0016043 (0.57) ! cellular component organization; GO:0071702 (0.55) ! organic substance transport; GO:0006928 (0.55) ! movement of cell or subcellular component; GO:0007165 (0.54) ! signal transduction; GO:0065008 (0.53) ! regulation of biological quality; GO:0044707 (0.53) ! single-multicellular organism process; GO:0051239 (0.52) ! regulation of multicellular organismal process; GO:0055092 (0.49) ! sterol homeostasis; GO:0045940 (0.49) ! positive regulation of steroid metabolic process; GO:0042157 (0.49) ! lipoprotein metabolic process; GO:0034645 (0.49) ! cellular macromolecule biosynthetic process; GO:0034377 (0.49) ! plasma lipoprotein particle assembly; GO:0016101 (0.49) ! diterpenoid metabolic process; GO:0015914 (0.49) ! phospholipid transport; GO:0010872 (0.49) ! regulation of cholesterol esterification; GO:0007265 (0.46) ! Ras protein signal transduction; GO:2000026 (0.44) ! regulation of multicellular organismal development; GO:0045595 (0.44) ! regulation of cell differentiation; GO:1904729 (0.40) ! regulation of intestinal lipid absorption; GO:1902653 (0.40) ! secondary alcohol biosynthetic process; GO:0090208 (0.40) ! positive regulation of triglyceride metabolic process; GO:0061365 (0.40) ! positive regulation of triglyceride lipase activity; GO:0055090 (0.40) ! acylglycerol homeostasis; GO:0051004 (0.40) ! regulation of lipoprotein lipase activity; GO:0050996 (0.40) ! positive regulation of lipid catabolic process; GO:0050727 (0.40) ! regulation of inflammatory response; GO:0046889 (0.40) ! positive regulation of lipid biosynthetic process; GO:0045923 (0.40) ! positive regulation of fatty acid metabolic process; GO:0042304 (0.40) ! regulation of fatty acid biosynthetic process; GO:0035023 (0.40) ! regulation of Rho protein signal transduction; GO:0034381 (0.40) ! plasma lipoprotein particle clearance; GO:0032488 (0.40) ! Cdc42 protein signal transduction; GO:0032374 (0.40) ! regulation of cholesterol transport; GO:0032102 (0.40) ! negative regulation of response to external stimulus; GO:0031348 (0.40) ! negative regulation of defense response; GO:0031331 (0.40) ! positive regulation of cellular catabolic process; GO:0031328 (0.40) ! positive regulation of cellular biosynthetic process; GO:0030299 (0.40) ! intestinal cholesterol absorption; GO:0016126 (0.40) ! sterol biosynthetic process; GO:0010896 (0.40) ! regulation of triglyceride catabolic process; GO:0006897 (0.40) ! endocytosis; GO:0010769 (0.38) ! regulation of cell morphogenesis involved in differentiation; GO:0030705 (0.36) ! cytoskeleton-dependent intracellular transport; GO:0007018 (0.36) ! microtubule-based movement; GO:0044767 (0.35) ! single-organism developmental process; GO:1900024 (0.30) ! regulation of substrate adhesion-dependent cell spreading; GO:0071560 (0.30) ! cellular response to transforming growth factor beta stimulus; GO:0070587 (0.30) ! regulation of cell-cell adhesion involved in gastrulation; GO:0060353 (0.30) ! regulation of cell adhesion molecule production; GO:0055114 (0.30) ! oxidation-reduction process; GO:0051492 (0.30) ! regulation of stress fiber assembly; GO:0051235 (0.30) ! maintenance of location; GO:0051129 (0.30) ! negative regulation of cellular component organization; GO:0050711 (0.30) ! negative regulation of interleukin-1 secretion; GO:0050706 (0.30) ! regulation of interleukin-1 beta secretion; GO:0050673 (0.30) ! epithelial cell proliferation; GO:0048732 (0.30) ! gland development; GO:0046579 (0.30) ! positive regulation of Ras protein signal transduction; GO:0046470 (0.30) ! phosphatidylcholine metabolic process; GO:0045055 (0.30) ! regulated exocytosis; GO:0043542 (0.30) ! endothelial cell migration; GO:0043086 (0.30) ! negative regulation of catalytic activity; GO:0042325 (0.30) ! regulation of phosphorylation; GO:0035376 (0.30) ! sterol import; GO:0035270 (0.30) ! endocrine system development; GO:0034114 (0.30) ! regulation of heterotypic cell-cell adhesion; GO:0032691 (0.30) ! negative regulation of interleukin-1 beta production; GO:0032233 (0.30) ! positive regulation of actin filament bundle assembly; GO:0031667 (0.30) ! response to nutrient levels; GO:0031647 (0.30) ! regulation of protein stability; GO:0031399 (0.30) ! regulation of protein modification process; GO:0031103 (0.30) ! axon regeneration; GO:0022408 (0.30) ! negative regulation of cell-cell adhesion; GO:0019637 (0.30) ! organophosphate metabolic process; GO:0018193 (0.30) ! peptidyl-amino acid modification; GO:0010901 (0.30) ! regulation of very-low-density lipoprotein particle remodeling; GO:0010811 (0.30) ! positive regulation of cell-substrate adhesion; GO:0010803 (0.30) ! regulation of tumor necrosis factor-mediated signaling pathway; GO:0010770 (0.30) ! positive regulation of cell morphogenesis involved in differentiation; GO:0007178 (0.30) ! transmembrane receptor protein serine/threonine kinase signaling pathway; GO:0006935 (0.30) ! chemotaxis; GO:0002739 (0.30) ! regulation of cytokine secretion involved in immune response; GO:0002719 (0.30) ! negative regulation of cytokine production involved in immune response; GO:0001960 (0.30) ! negative regulation of cytokine-mediated signaling pathway; GO:0000165 (0.30) ! MAPK cascade; GO:0002244 (0.23) ! hematopoietic progenitor cell differentiation; GO:0071786 (0.15) ! endoplasmic reticulum tubular network organization; GO:0050770 (0.12) ! regulation of axonogenesis; GO:0042110 (0.12) ! T cell activation; GO:0006605 (0.12) ! protein targeting; GO:0042733 (0.08) ! embryonic digit morphogenesis; GO:0035115 (0.08) ! embryonic forelimb morphogenesis; GO:0032330 (0.08) ! regulation of chondrocyte differentiation; GO:0007596 (0.08) ! blood coagulation GO:0044464 (0.97) ! cell part; GO:0044424 (0.91) ! intracellular part; GO:0016020 (0.79) ! membrane; GO:0044446 (0.73) ! intracellular organelle part; GO:0032991 (0.71) ! macromolecular complex; GO:0044425 (0.62) ! membrane part; GO:0044444 (0.60) ! cytoplasmic part; GO:0043234 (0.54) ! protein complex; GO:0043226 (0.54) ! organelle; GO:0016021 (0.54) ! integral component of membrane; GO:0043229 (0.49) ! intracellular organelle; GO:0043227 (0.49) ! membrane-bounded organelle; GO:0044430 (0.47) ! cytoskeletal part; GO:0005886 (0.47) ! plasma membrane; GO:0043231 (0.44) ! intracellular membrane-bounded organelle; GO:0005871 (0.44) ! kinesin complex; GO:0070062 (0.35) ! extracellular exosome; GO:0005829 (0.33) ! cytosol; GO:0005634 (0.33) ! nucleus; GO:0072562 (0.29) ! blood microparticle; GO:0042627 (0.29) ! chylomicron; GO:0034364 (0.29) ! high-density lipoprotein particle; GO:0034361 (0.29) ! very-low-density lipoprotein particle; GO:0005737 (0.29) ! cytoplasm; GO:0005615 (0.29) ! extracellular space; GO:0005576 (0.29) ! extracellular region; GO:0044432 (0.27) ! endoplasmic reticulum part; GO:0009986 (0.23) ! cell surface; GO:0043005 (0.20) ! neuron projection; GO:0071782 (0.18) ! endoplasmic reticulum tubular network; GO:0005789 (0.18) ! endoplasmic reticulum membrane; GO:0098796 (0.17) ! membrane protein complex; GO:0044459 (0.17) ! plasma membrane part; GO:0043233 (0.17) ! organelle lumen; GO:0005769 (0.17) ! early endosome; GO:0030424 (0.15) ! axon; GO:0005903 (0.13) ! brush border; GO:0071682 (0.11) ! endocytic vesicle lumen; GO:0043190 (0.11) ! ATP-binding cassette (ABC) transporter complex; GO:0034366 (0.11) ! spherical high-density lipoprotein particle; GO:0034365 (0.11) ! discoidal high-density lipoprotein particle; GO:0034363 (0.11) ! intermediate-density lipoprotein particle; GO:0034362 (0.11) ! low-density lipoprotein particle; GO:0031012 (0.11) ! extracellular matrix; GO:0030139 (0.11) ! endocytic vesicle; GO:0005794 (0.11) ! Golgi apparatus; GO:0005788 (0.11) ! endoplasmic reticulum lumen; GO:0005783 (0.11) ! endoplasmic reticulum; GO:0061645 (0.06) ! endocytic patch; GO:0046581 (0.06) ! intercellular canaliculus; GO:0043025 (0.06) ! neuronal cell body; GO:0034774 (0.06) ! secretory granule lumen; GO:0030425 (0.06) ! dendrite; GO:0016324 (0.06) ! apical plasma membrane; GO:0009579 (0.06) ! thylakoid; GO:0009535 (0.06) ! chloroplast thylakoid membrane; GO:0009523 (0.06) ! photosystem II; GO:0009507 (0.06) ! chloroplast; GO:0005935 (0.06) ! cellular bud neck; GO:0005934 (0.06) ! cellular bud tip; GO:0001400 (0.06) ! mating projection base; GO:0000144 (0.06) ! cellular bud neck septin ring 1 14235673-14236862 (17p12) Testis: 18.64; Spleen: 0.41; Small Intestine - Terminal Ileum: 0.30; Brain - Cerebellum: 0.24; Cells - EBV-transformed lymphocytes: 0.24; Esophagus - Mucosa: 0.23; Prostate: 0.20; Skin - Not Sun Exposed (Suprapubic): 0.20; Skin - Sun Exposed (Lower leg): 0.19; Brain - Cerebellar Hemisphere: 0.19; Cervix - Ectocervix: 0.17; Cells - Transformed fibroblasts: 0.17; Lung: 0.17; Fallopian Tube: 0.16; Vagina: 0.16; Colon - Transverse: 0.16; Liver: 0.15; Thyroid: 0.14; Minor Salivary Gland: 0.14; Artery - Aorta: 0.14; Cervix - Endocervix: 0.13; Stomach: 0.11; Ovary: 0.11; Pituitary: 0.11; Adrenal Gland: 0.10; Uterus: 0.09; Heart - Atrial Appendage: 0.09; Heart - Left Ventricle: 0.08; Esophagus - Gastroesophageal Junction: 0.08; Artery - Coronary: 0.08; Esophagus - Muscularis: 0.08; Brain - Spinal cord (cervical c-1): 0.07; Breast - Mammary Tissue: 0.07; Nerve - Tibial: 0.07; Kidney - Cortex: 0.07; Colon - Sigmoid: 0.06; Bladder: 0.06; Whole Blood: 0.06; Adipose - Subcutaneous: 0.06; Adipose - Visceral (Omentum): 0.06; Artery - Tibial: 0.05; Pancreas: 0.05; Brain - Frontal Cortex (BA9): 0.04; Muscle - Skeletal: 0.04; Brain - Cortex: 0.04; Brain - Hippocampus: 0.03; Brain - Substantia nigra: 0.03; Brain - Nucleus accumbens (basal ganglia): 0.03; Brain - Hypothalamus: 0.03; MFSCCFPTSRGCCFRNGGSESLFRRCRRRLIPHPRRLSPVVIRRIQVPQDSLGQALAGQATPEIPLGLQLHTVLVQEIQELIEAQTLAPGPCAEVRALPAPAAEPEPAWEEAPPERALELEGAPAKDQTNEELPEITEVPESIKRRLGRRVPAATPAPRGNLLLQAWMRVHSWASRLFAPNVLPGTGP LRRC75A Leucine-rich repeat-containing protein 75A LR75A_HUMAN (Q8NAA5-1) GO:0030234 (0.37) ! enzyme regulator activity; GO:0004857 (0.36) ! enzyme inhibitor activity; GO:0005102 (0.20) ! receptor binding; GO:0008134 (0.19) ! transcription factor binding; GO:0042974 (0.17) ! retinoic acid receptor binding; GO:0003824 (0.16) ! catalytic activity; GO:0097159 (0.14) ! organic cyclic compound binding; GO:1901363 (0.13) ! heterocyclic compound binding; GO:0097367 (0.11) ! carbohydrate derivative binding; GO:0019899 (0.10) ! enzyme binding; GO:0016740 (0.10) ! transferase activity; GO:0019904 (0.09) ! protein domain specific binding; GO:0004872 (0.08) ! receptor activity; GO:0003676 (0.08) ! nucleic acid binding; GO:0008092 (0.07) ! cytoskeletal protein binding; GO:0004842 (0.06) ! ubiquitin-protein transferase activity; GO:0003779 (0.06) ! actin binding; GO:0000166 (0.06) ! nucleotide binding; GO:0038023 (0.05) ! signaling receptor activity; GO:0016787 (0.05) ! hydrolase activity; GO:0005539 (0.05) ! glycosaminoglycan binding; GO:0005524 (0.05) ! ATP binding; GO:0005523 (0.05) ! tropomyosin binding; GO:0003677 (0.05) ! DNA binding; GO:0045502 (0.04) ! dynein binding; GO:0043565 (0.04) ! sequence-specific DNA binding; GO:0042393 (0.04) ! histone binding; GO:0050700 (0.03) ! CARD domain binding; GO:0048495 (0.03) ! Roundabout binding; GO:0042277 (0.03) ! peptide binding; GO:0032403 (0.03) ! protein complex binding; GO:0019902 (0.03) ! phosphatase binding; GO:0008201 (0.03) ! heparin binding; GO:0008047 (0.03) ! enzyme activator activity; GO:0004888 (0.03) ! transmembrane signaling receptor activity; GO:0004860 (0.03) ! protein kinase inhibitor activity; GO:0004197 (0.03) ! cysteine-type endopeptidase activity; GO:0003723 (0.03) ! RNA binding; GO:0097110 (0.02) ! scaffold protein binding; GO:0044212 (0.02) ! transcription regulatory region DNA binding; GO:0042834 (0.02) ! peptidoglycan binding; GO:0042802 (0.02) ! identical protein binding; GO:0032500 (0.02) ! muramyl dipeptide binding; GO:0032090 (0.02) ! Pyrin domain binding; GO:0015321 (0.02) ! sodium-dependent phosphate transmembrane transporter activity; GO:0008656 (0.02) ! cysteine-type endopeptidase activator activity involved in apoptotic process; GO:0008528 (0.02) ! G-protein coupled peptide receptor activity; GO:0005436 (0.02) ! sodium:phosphate symporter activity; GO:0005030 (0.02) ! neurotrophin receptor activity; GO:0004674 (0.02) ! protein serine/threonine kinase activity; GO:0004663 (0.02) ! Rab geranylgeranyltransferase activity; GO:0004198 (0.02) ! calcium-dependent cysteine-type endopeptidase activity; GO:0003725 (0.02) ! double-stranded RNA binding; GO:0003690 (0.02) ! double-stranded DNA binding; GO:0097153 (0.01) ! cysteine-type endopeptidase activity involved in apoptotic process; GO:0051879 (0.01) ! Hsp90 protein binding; GO:0044822 (0.01) ! poly(A) RNA binding; GO:0042803 (0.01) ! protein homodimerization activity; GO:0035064 (0.01) ! methylated histone binding; GO:0033612 (0.01) ! receptor serine/threonine kinase binding; GO:0031491 (0.01) ! nucleosome binding; GO:0030544 (0.01) ! Hsp70 protein binding; GO:0019901 (0.01) ! protein kinase binding; GO:0019199 (0.01) ! transmembrane receptor protein kinase activity; GO:0017137 (0.01) ! Rab GTPase binding; GO:0016922 (0.01) ! ligand-dependent nuclear receptor binding; GO:0016500 (0.01) ! protein-hormone receptor activity; GO:0008428 (0.01) ! ribonuclease inhibitor activity; GO:0008327 (0.01) ! methyl-CpG binding; GO:0008188 (0.01) ! neuropeptide receptor activity; GO:0005543 (0.01) ! phospholipid binding; GO:0005262 (0.01) ! calcium channel activity; GO:0005096 (0.01) ! GTPase activator activity; GO:0005000 (0.01) ! vasopressin receptor activity; GO:0004826 (0.01) ! phenylalanine-tRNA ligase activity; GO:0004535 (0.01) ! poly(A)-specific ribonuclease activity; GO:0004177 (0.01) ! aminopeptidase activity; GO:0003727 (0.01) ! single-stranded RNA binding; GO:0003714 (0.01) ! transcription corepressor activity; GO:0000979 (0.01) ! RNA polymerase II core promoter sequence-specific DNA binding GO:0065007 (0.73) ! biological regulation; GO:0050789 (0.73) ! regulation of biological process; GO:0009987 (0.67) ! cellular process; GO:0044699 (0.61) ! single-organism process; GO:0050794 (0.54) ! regulation of cellular process; GO:0071704 (0.48) ! organic substance metabolic process; GO:0044767 (0.48) ! single-organism developmental process; GO:0044238 (0.47) ! primary metabolic process; GO:0043170 (0.47) ! macromolecule metabolic process; GO:0065009 (0.45) ! regulation of molecular function; GO:0050790 (0.44) ! regulation of catalytic activity; GO:0044237 (0.44) ! cellular metabolic process; GO:0051239 (0.43) ! regulation of multicellular organismal process; GO:0044260 (0.43) ! cellular macromolecule metabolic process; GO:0019222 (0.40) ! regulation of metabolic process; GO:0048518 (0.39) ! positive regulation of biological process; GO:0044092 (0.39) ! negative regulation of molecular function; GO:0009057 (0.39) ! macromolecule catabolic process; GO:0060255 (0.38) ! regulation of macromolecule metabolic process; GO:0050793 (0.38) ! regulation of developmental process; GO:0031323 (0.38) ! regulation of cellular metabolic process; GO:2000026 (0.37) ! regulation of multicellular organismal development; GO:0090304 (0.37) ! nucleic acid metabolic process; GO:0044265 (0.37) ! cellular macromolecule catabolic process; GO:0080090 (0.36) ! regulation of primary metabolic process; GO:0048583 (0.36) ! regulation of response to stimulus; GO:0022603 (0.36) ! regulation of anatomical structure morphogenesis; GO:0048646 (0.35) ! anatomical structure formation involved in morphogenesis; GO:1901342 (0.34) ! regulation of vasculature development; GO:0016071 (0.34) ! mRNA metabolic process; GO:0006401 (0.34) ! RNA catabolic process; GO:0048522 (0.33) ! positive regulation of cellular process; GO:0048519 (0.33) ! negative regulation of biological process; GO:0001525 (0.33) ! angiogenesis; GO:0044763 (0.32) ! single-organism cellular process; GO:0048523 (0.31) ! negative regulation of cellular process; GO:0009966 (0.28) ! regulation of signal transduction; GO:0042981 (0.26) ! regulation of apoptotic process; GO:0031326 (0.26) ! regulation of cellular biosynthetic process; GO:0010556 (0.26) ! regulation of macromolecule biosynthetic process; GO:0010468 (0.26) ! regulation of gene expression; GO:2000112 (0.25) ! regulation of cellular macromolecule biosynthetic process; GO:1903506 (0.25) ! regulation of nucleic acid-templated transcription; GO:0009968 (0.25) ! negative regulation of signal transduction; GO:0031324 (0.24) ! negative regulation of cellular metabolic process; GO:0006355 (0.24) ! regulation of transcription, DNA-templated; GO:0050896 (0.23) ! response to stimulus; GO:0045595 (0.22) ! regulation of cell differentiation; GO:0010605 (0.21) ! negative regulation of macromolecule metabolic process; GO:0031327 (0.19) ! negative regulation of cellular biosynthetic process; GO:0010558 (0.19) ! negative regulation of macromolecule biosynthetic process; GO:0008284 (0.19) ! positive regulation of cell proliferation; GO:0060548 (0.18) ! negative regulation of cell death; GO:0045892 (0.18) ! negative regulation of transcription, DNA-templated; GO:0016043 (0.18) ! cellular component organization; GO:0048387 (0.17) ! negative regulation of retinoic acid receptor signaling pathway; GO:0045596 (0.17) ! negative regulation of cell differentiation; GO:0043066 (0.17) ! negative regulation of apoptotic process; GO:0006950 (0.17) ! response to stress; GO:0019538 (0.15) ! protein metabolic process; GO:0007165 (0.15) ! signal transduction; GO:0032268 (0.14) ! regulation of cellular protein metabolic process; GO:0009653 (0.14) ! anatomical structure morphogenesis; GO:0050776 (0.13) ! regulation of immune response; GO:0048584 (0.13) ! positive regulation of response to stimulus; GO:0010604 (0.13) ! positive regulation of macromolecule metabolic process; GO:0006952 (0.13) ! defense response; GO:0051336 (0.12) ! regulation of hydrolase activity; GO:0031347 (0.12) ! regulation of defense response; GO:0031325 (0.12) ! positive regulation of cellular metabolic process; GO:0009605 (0.12) ! response to external stimulus; GO:0002376 (0.12) ! immune system process; GO:0050778 (0.11) ! positive regulation of immune response; GO:0048869 (0.11) ! cellular developmental process; GO:0044093 (0.11) ! positive regulation of molecular function; GO:0032501 (0.11) ! multicellular organismal process; GO:0001817 (0.11) ! regulation of cytokine production; GO:0051704 (0.10) ! multi-organism process; GO:0044707 (0.10) ! single-multicellular organism process; GO:0043207 (0.10) ! response to external biotic stimulus; GO:0032879 (0.10) ! regulation of localization; GO:0030030 (0.10) ! cell projection organization; GO:1902531 (0.09) ! regulation of intracellular signal transduction; GO:0098542 (0.09) ! defense response to other organism; GO:0052547 (0.09) ! regulation of peptidase activity; GO:0051345 (0.09) ! positive regulation of hydrolase activity; GO:0051179 (0.09) ! localization; GO:0045088 (0.09) ! regulation of innate immune response; GO:0042221 (0.09) ! response to chemical; GO:0032270 (0.09) ! positive regulation of cellular protein metabolic process; GO:0051716 (0.08) ! cellular response to stimulus; GO:0051234 (0.08) ! establishment of localization; GO:0048858 (0.08) ! cell projection morphogenesis; GO:0045089 (0.08) ! positive regulation of innate immune response; GO:0043280 (0.08) ! positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0019220 (0.08) ! regulation of phosphate metabolic process; GO:0010033 (0.08) ! response to organic substance; GO:0001819 (0.08) ! positive regulation of cytokine production; GO:0065008 (0.07) ! regulation of biological quality; GO:0051223 (0.07) ! regulation of protein transport; GO:0030163 (0.07) ! protein catabolic process; GO:0022607 (0.07) ! cellular component assembly; GO:0006810 (0.07) ! transport; GO:0006508 (0.07) ! proteolysis; GO:0006464 (0.07) ! cellular protein modification process; GO:0002253 (0.07) ! activation of immune response; GO:1902532 (0.06) ! negative regulation of intracellular signal transduction; GO:1901700 (0.06) ! response to oxygen-containing compound; GO:0051090 (0.06) ! regulation of sequence-specific DNA binding transcription factor activity; GO:0050715 (0.06) ! positive regulation of cytokine secretion; GO:0050704 (0.06) ! regulation of interleukin-1 secretion; GO:0048856 (0.06) ! anatomical structure development; GO:0045936 (0.06) ! negative regulation of phosphate metabolic process; GO:0042325 (0.06) ! regulation of phosphorylation; GO:0032651 (0.06) ! regulation of interleukin-1 beta production; GO:0031399 (0.06) ! regulation of protein modification process; GO:0010557 (0.06) ! positive regulation of macromolecule biosynthetic process; GO:0008219 (0.06) ! cell death; GO:0007166 (0.06) ! cell surface receptor signaling pathway; GO:0006919 (0.06) ! activation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0002221 (0.06) ! pattern recognition receptor signaling pathway; GO:0071310 (0.05) ! cellular response to organic substance; GO:0070997 (0.05) ! neuron death; GO:0051603 (0.05) ! proteolysis involved in cellular protein catabolic process; GO:0051338 (0.05) ! regulation of transferase activity; GO:0051241 (0.05) ! negative regulation of multicellular organismal process; GO:0051128 (0.05) ! regulation of cellular component organization; GO:0050718 (0.05) ! positive regulation of interleukin-1 beta secretion; GO:0048812 (0.05) ! neuron projection morphogenesis; GO:0045944 (0.05) ! positive regulation of transcription from RNA polymerase II promoter; GO:0043122 (0.05) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043086 (0.05) ! negative regulation of catalytic activity; GO:0042742 (0.05) ! defense response to bacterium; GO:0032101 (0.05) ! regulation of response to external stimulus; GO:0009719 (0.05) ! response to endogenous stimulus; GO:0006996 (0.05) ! organelle organization; GO:0006955 (0.05) ! immune response; GO:0006915 (0.05) ! apoptotic process; GO:0001932 (0.05) ! regulation of protein phosphorylation; GO:0001816 (0.05) ! cytokine production; GO:1902589 (0.04) ! single-organism organelle organization; GO:0051606 (0.04) ! detection of stimulus; GO:0051402 (0.04) ! neuron apoptotic process; GO:0050727 (0.04) ! regulation of inflammatory response; GO:0043933 (0.04) ! macromolecular complex subunit organization; GO:0043549 (0.04) ! regulation of kinase activity; GO:0043161 (0.04) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0040007 (0.04) ! growth; GO:0033554 (0.04) ! cellular response to stress; GO:0032611 (0.04) ! interleukin-1 beta production; GO:0032495 (0.04) ! response to muramyl dipeptide; GO:0032269 (0.04) ! negative regulation of cellular protein metabolic process; GO:0032088 (0.04) ! negative regulation of NF-kappaB transcription factor activity; GO:0031348 (0.04) ! negative regulation of defense response; GO:0031344 (0.04) ! regulation of cell projection organization; GO:0022414 (0.04) ! reproductive process; GO:0016567 (0.04) ! protein ubiquitination; GO:0009967 (0.04) ! positive regulation of signal transduction; GO:0007476 (0.04) ! imaginal disc-derived wing morphogenesis; GO:0007409 (0.04) ! axonogenesis; GO:0006954 (0.04) ! inflammatory response; GO:0006928 (0.04) ! movement of cell or subcellular component; GO:0002224 (0.04) ! toll-like receptor signaling pathway; GO:0001818 (0.04) ! negative regulation of cytokine production; GO:1901701 (0.03) ! cellular response to oxygen-containing compound; GO:0070925 (0.03) ! organelle assembly; GO:0070269 (0.03) ! pyroptosis; GO:0060560 (0.03) ! developmental growth involved in morphogenesis; GO:0060271 (0.03) ! cilium morphogenesis; GO:0051346 (0.03) ! negative regulation of hydrolase activity; GO:0051270 (0.03) ! regulation of cellular component movement; GO:0051224 (0.03) ! negative regulation of protein transport; GO:0051130 (0.03) ! positive regulation of cellular component organization; GO:0051094 (0.03) ! positive regulation of developmental process; GO:0051092 (0.03) ! positive regulation of NF-kappaB transcription factor activity; GO:0050870 (0.03) ! positive regulation of T cell activation; GO:0050777 (0.03) ! negative regulation of immune response; GO:0050770 (0.03) ! regulation of axonogenesis; GO:0050728 (0.03) ! negative regulation of inflammatory response; GO:0048513 (0.03) ! animal organ development; GO:0045859 (0.03) ! regulation of protein kinase activity; GO:0045597 (0.03) ! positive regulation of cell differentiation; GO:0045087 (0.03) ! innate immune response; GO:0044765 (0.03) ! single-organism transport; GO:0044702 (0.03) ! single organism reproductive process; GO:0043124 (0.03) ! negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:0040011 (0.03) ! locomotion; GO:0035556 (0.03) ! intracellular signal transduction; GO:0032675 (0.03) ! regulation of interleukin-6 production; GO:0032610 (0.03) ! interleukin-1 alpha production; GO:0031297 (0.03) ! replication fork processing; GO:0031146 (0.03) ! SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; GO:0030154 (0.03) ! cell differentiation; GO:0030031 (0.03) ! cell projection assembly; GO:0022402 (0.03) ! cell cycle process; GO:0016049 (0.03) ! cell growth; GO:0015031 (0.03) ! protein transport; GO:0010927 (0.03) ! cellular component assembly involved in morphogenesis; GO:0009595 (0.03) ! detection of biotic stimulus; GO:0007015 (0.03) ! actin filament organization; GO:0006461 (0.03) ! protein complex assembly; GO:0002830 (0.03) ! positive regulation of type 2 immune response; GO:0002720 (0.03) ! positive regulation of cytokine production involved in immune response; GO:0002705 (0.03) ! positive regulation of leukocyte mediated immunity; GO:0002237 (0.03) ! response to molecule of bacterial origin; GO:0001933 (0.03) ! negative regulation of protein phosphorylation; GO:0000724 (0.03) ! double-strand break repair via homologous recombination; GO:2000813 (0.02) ! negative regulation of barbed-end actin filament capping; GO:2000553 (0.02) ! positive regulation of T-helper 2 cell cytokine production; GO:1902745 (0.02) ! positive regulation of lamellipodium organization; GO:1901222 (0.02) ! regulation of NIK/NF-kappaB signaling; GO:0071225 (0.02) ! cellular response to muramyl dipeptide; GO:0070431 (0.02) ! nucleotide-binding oligomerization domain containing 2 signaling pathway; GO:0070372 (0.02) ! regulation of ERK1 and ERK2 cascade; GO:0055085 (0.02) ! transmembrane transport; GO:0051641 (0.02) ! cellular localization; GO:0051639 (0.02) ! actin filament network formation; GO:0051607 (0.02) ! defense response to virus; GO:0050711 (0.02) ! negative regulation of interleukin-1 secretion; GO:0048846 (0.02) ! axon extension involved in axon guidance; GO:0046426 (0.02) ! negative regulation of JAK-STAT cascade; GO:0045630 (0.02) ! positive regulation of T-helper 2 cell differentiation; GO:0045345 (0.02) ! positive regulation of MHC class I biosynthetic process; GO:0044351 (0.02) ! macropinocytosis; GO:0043623 (0.02) ! cellular protein complex assembly; GO:0043123 (0.02) ! positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0042992 (0.02) ! negative regulation of transcription factor import into nucleus; GO:0042592 (0.02) ! homeostatic process; GO:0042384 (0.02) ! cilium assembly; GO:0042345 (0.02) ! regulation of NF-kappaB import into nucleus; GO:0035385 (0.02) ! Roundabout signaling pathway; GO:0032753 (0.02) ! positive regulation of interleukin-4 production; GO:0032715 (0.02) ! negative regulation of interleukin-6 production; GO:0032680 (0.02) ! regulation of tumor necrosis factor production; GO:0032496 (0.02) ! response to lipopolysaccharide; GO:0032490 (0.02) ! detection of molecule of bacterial origin; GO:0032479 (0.02) ! regulation of type I interferon production; GO:0030335 (0.02) ! positive regulation of cell migration; GO:0030036 (0.02) ! actin cytoskeleton organization; GO:0019221 (0.02) ! cytokine-mediated signaling pathway; GO:0018344 (0.02) ! protein geranylgeranylation; GO:0016477 (0.02) ! cell migration; GO:0010923 (0.02) ! negative regulation of phosphatase activity; GO:0009628 (0.02) ! response to abiotic stimulus; GO:0009306 (0.02) ! protein secretion; GO:0007275 (0.02) ! multicellular organism development; GO:0006814 (0.02) ! sodium ion transport; GO:0006469 (0.02) ! negative regulation of protein kinase activity; GO:0006082 (0.02) ! organic acid metabolic process; GO:0003008 (0.02) ! system process; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0000086 (0.02) ! G2/M transition of mitotic cell cycle; GO:2000363 (0.01) ! positive regulation of prostaglandin-E synthase activity; GO:2000327 (0.01) ! positive regulation of ligand-dependent nuclear receptor transcription coactivator activity; GO:2000321 (0.01) ! positive regulation of T-helper 17 cell differentiation; GO:2000110 (0.01) ! negative regulation of macrophage apoptotic process; GO:1901224 (0.01) ! positive regulation of NIK/NF-kappaB signaling; GO:1901223 (0.01) ! negative regulation of NIK/NF-kappaB signaling; GO:1900424 (0.01) ! regulation of defense response to bacterium; GO:1900029 (0.01) ! positive regulation of ruffle assembly; GO:1900026 (0.01) ! positive regulation of substrate adhesion-dependent cell spreading; GO:1900017 (0.01) ! positive regulation of cytokine production involved in inflammatory response; GO:0099402 (0.01) ! plant organ development; GO:0097300 (0.01) ! programmed necrotic cell death; GO:0090091 (0.01) ! positive regulation of extracellular matrix disassembly; GO:0071910 (0.01) ! determination of liver left/right asymmetry; GO:0071907 (0.01) ! determination of digestive tract left/right asymmetry; GO:0071407 (0.01) ! cellular response to organic cyclic compound; GO:0071222 (0.01) ! cellular response to lipopolysaccharide; GO:0070966 (0.01) ! nuclear-transcribed mRNA catabolic process, no-go decay; GO:0070374 (0.01) ! positive regulation of ERK1 and ERK2 cascade; GO:0070373 (0.01) ! negative regulation of ERK1 and ERK2 cascade; GO:0061339 (0.01) ! establishment or maintenance of monopolar cell polarity; GO:0060972 (0.01) ! left/right pattern formation; GO:0060585 (0.01) ! positive regulation of prostaglandin-endoperoxide synthase activity; GO:0060340 (0.01) ! positive regulation of type I interferon-mediated signaling pathway; GO:0060339 (0.01) ! negative regulation of type I interferon-mediated signaling pathway; GO:0060335 (0.01) ! positive regulation of interferon-gamma-mediated signaling pathway; GO:0051770 (0.01) ! positive regulation of nitric-oxide synthase biosynthetic process; GO:0051638 (0.01) ! barbed-end actin filament uncapping; GO:0051496 (0.01) ! positive regulation of stress fiber assembly; GO:0051301 (0.01) ! cell division; GO:0051259 (0.01) ! protein oligomerization; GO:0051168 (0.01) ! nuclear export; GO:0051014 (0.01) ! actin filament severing; GO:0050878 (0.01) ! regulation of body fluid levels; GO:0050871 (0.01) ! positive regulation of B cell activation; GO:0050713 (0.01) ! negative regulation of interleukin-1 beta secretion; GO:0050701 (0.01) ! interleukin-1 secretion; GO:0050679 (0.01) ! positive regulation of epithelial cell proliferation; GO:0048878 (0.01) ! chemical homeostasis; GO:0048872 (0.01) ! homeostasis of number of cells; GO:0048580 (0.01) ! regulation of post-embryonic development; GO:0048511 (0.01) ! rhythmic process; GO:0046645 (0.01) ! positive regulation of gamma-delta T cell activation; GO:0046415 (0.01) ! urate metabolic process; GO:0046330 (0.01) ! positive regulation of JNK cascade; GO:0045807 (0.01) ! positive regulation of endocytosis; GO:0045765 (0.01) ! regulation of angiogenesis; GO:0045751 (0.01) ! negative regulation of Toll signaling pathway; GO:0045747 (0.01) ! positive regulation of Notch signaling pathway; GO:0045416 (0.01) ! positive regulation of interleukin-8 biosynthetic process; GO:0045409 (0.01) ! negative regulation of interleukin-6 biosynthetic process; GO:0045359 (0.01) ! positive regulation of interferon-beta biosynthetic process; GO:0045356 (0.01) ! positive regulation of interferon-alpha biosynthetic process; GO:0045078 (0.01) ! positive regulation of interferon-gamma biosynthetic process; GO:0044546 (0.01) ! NLRP3 inflammasome complex assembly; GO:0044458 (0.01) ! motile cilium assembly; GO:0044319 (0.01) ! wound healing, spreading of cells; GO:0043928 (0.01) ! exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; GO:0043903 (0.01) ! regulation of symbiosis, encompassing mutualism through parasitism; GO:0043901 (0.01) ! negative regulation of multi-organism process; GO:0043552 (0.01) ! positive regulation of phosphatidylinositol 3-kinase activity; GO:0043487 (0.01) ! regulation of RNA stability; GO:0042994 (0.01) ! cytoplasmic sequestering of transcription factor; GO:0042787 (0.01) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0042494 (0.01) ! detection of bacterial lipoprotein; GO:0042347 (0.01) ! negative regulation of NF-kappaB import into nucleus; GO:0042110 (0.01) ! T cell activation; GO:0036159 (0.01) ! inner dynein arm assembly; GO:0036158 (0.01) ! outer dynein arm assembly; GO:0035725 (0.01) ! sodium ion transmembrane transport; GO:0035469 (0.01) ! determination of pancreatic left/right asymmetry; GO:0035419 (0.01) ! activation of MAPK activity involved in innate immune response; GO:0034248 (0.01) ! regulation of cellular amide metabolic process; GO:0034122 (0.01) ! negative regulation of toll-like receptor signaling pathway; GO:0034097 (0.01) ! response to cytokine; GO:0032760 (0.01) ! positive regulation of tumor necrosis factor production; GO:0032755 (0.01) ! positive regulation of interleukin-6 production; GO:0032754 (0.01) ! positive regulation of interleukin-5 production; GO:0032740 (0.01) ! positive regulation of interleukin-17 production; GO:0032736 (0.01) ! positive regulation of interleukin-13 production; GO:0032733 (0.01) ! positive regulation of interleukin-10 production; GO:0032720 (0.01) ! negative regulation of tumor necrosis factor production; GO:0032695 (0.01) ! negative regulation of interleukin-12 production; GO:0032663 (0.01) ! regulation of interleukin-2 production; GO:0032661 (0.01) ! regulation of interleukin-18 production; GO:0032621 (0.01) ! interleukin-18 production; GO:0032498 (0.01) ! detection of muramyl dipeptide; GO:0032480 (0.01) ! negative regulation of type I interferon production; GO:0031953 (0.01) ! negative regulation of protein autophosphorylation; GO:0031529 (0.01) ! ruffle organization; GO:0031396 (0.01) ! regulation of protein ubiquitination; GO:0030587 (0.01) ! sorocarp development; GO:0030324 (0.01) ! lung development; GO:0030318 (0.01) ! melanocyte differentiation; GO:0030277 (0.01) ! maintenance of gastrointestinal epithelium; GO:0030239 (0.01) ! myofibril assembly; GO:0030032 (0.01) ! lamellipodium assembly; GO:0022008 (0.01) ! neurogenesis; GO:0019827 (0.01) ! stem cell population maintenance; GO:0017085 (0.01) ! response to insecticide; GO:0016045 (0.01) ! detection of bacterium; GO:0010592 (0.01) ! positive regulation of lamellipodium assembly; GO:0010506 (0.01) ! regulation of autophagy; GO:0010305 (0.01) ! leaf vascular tissue pattern formation; GO:0010165 (0.01) ! response to X-ray; GO:0009934 (0.01) ! regulation of meristem structural organization; GO:0009933 (0.01) ! meristem structural organization; GO:0009888 (0.01) ! tissue development; GO:0009887 (0.01) ! organ morphogenesis; GO:0009792 (0.01) ! embryo development ending in birth or egg hatching; GO:0009742 (0.01) ! brassinosteroid mediated signaling pathway; GO:0009725 (0.01) ! response to hormone; GO:0009611 (0.01) ! response to wounding; GO:0009553 (0.01) ! embryo sac development; GO:0009058 (0.01) ! biosynthetic process; GO:0008588 (0.01) ! release of cytoplasmic sequestered NF-kappaB; GO:0008283 (0.01) ! cell proliferation; GO:0007614 (0.01) ! short-term memory; GO:0007584 (0.01) ! response to nutrient; GO:0007423 (0.01) ! sensory organ development; GO:0007411 (0.01) ! axon guidance; GO:0007283 (0.01) ! spermatogenesis; GO:0007254 (0.01) ! JNK cascade; GO:0007249 (0.01) ! I-kappaB kinase/NF-kappaB signaling; GO:0007186 (0.01) ! G-protein coupled receptor signaling pathway; GO:0007067 (0.01) ! mitotic nuclear division; GO:0006606 (0.01) ! protein import into nucleus; GO:0006432 (0.01) ! phenylalanyl-tRNA aminoacylation; GO:0006325 (0.01) ! chromatin organization; GO:0003356 (0.01) ! regulation of cilium beat frequency; GO:0003341 (0.01) ! cilium movement; GO:0002862 (0.01) ! negative regulation of inflammatory response to antigenic stimulus; GO:0002832 (0.01) ! negative regulation of response to biotic stimulus; GO:0002732 (0.01) ! positive regulation of dendritic cell cytokine production; GO:0002698 (0.01) ! negative regulation of immune effector process; GO:0002674 (0.01) ! negative regulation of acute inflammatory response; GO:0002606 (0.01) ! positive regulation of dendritic cell antigen processing and presentation; GO:0002374 (0.01) ! cytokine secretion involved in immune response; GO:0002367 (0.01) ! cytokine production involved in immune response; GO:0002227 (0.01) ! innate immune response in mucosa; GO:0001947 (0.01) ! heart looping; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter GO:0044464 (1.00) ! cell part; GO:0044424 (0.89) ! intracellular part; GO:0043226 (0.76) ! organelle; GO:0043227 (0.72) ! membrane-bounded organelle; GO:0005737 (0.69) ! cytoplasm; GO:0043229 (0.63) ! intracellular organelle; GO:0044444 (0.60) ! cytoplasmic part; GO:0044446 (0.59) ! intracellular organelle part; GO:0043234 (0.58) ! protein complex; GO:0016020 (0.57) ! membrane; GO:0043231 (0.56) ! intracellular membrane-bounded organelle; GO:0005886 (0.45) ! plasma membrane; GO:0044421 (0.38) ! extracellular region part; GO:0005634 (0.37) ! nucleus; GO:0031988 (0.36) ! membrane-bounded vesicle; GO:0070062 (0.35) ! extracellular exosome; GO:0044425 (0.33) ! membrane part; GO:0031224 (0.32) ! intrinsic component of membrane; GO:0044428 (0.31) ! nuclear part; GO:0044430 (0.28) ! cytoskeletal part; GO:0016021 (0.27) ! integral component of membrane; GO:0005829 (0.27) ! cytosol; GO:0044459 (0.23) ! plasma membrane part; GO:0061702 (0.21) ! inflammasome complex; GO:0031226 (0.21) ! intrinsic component of plasma membrane; GO:0005654 (0.20) ! nucleoplasm; GO:0043232 (0.18) ! intracellular non-membrane-bounded organelle; GO:0032311 (0.17) ! angiogenin-PRI complex; GO:0005887 (0.16) ! integral component of plasma membrane; GO:0031090 (0.11) ! organelle membrane; GO:0009986 (0.11) ! cell surface; GO:0005622 (0.11) ! intracellular; GO:0072557 (0.10) ! IPAF inflammasome complex; GO:0044427 (0.10) ! chromosomal part; GO:0005876 (0.10) ! spindle microtubule; GO:0005576 (0.10) ! extracellular region; GO:0072558 (0.09) ! NLRP1 inflammasome complex; GO:0031012 (0.09) ! extracellular matrix; GO:0005856 (0.09) ! cytoskeleton; GO:0005815 (0.09) ! microtubule organizing center; GO:1902494 (0.08) ! catalytic complex; GO:0005813 (0.08) ! centrosome; GO:0005794 (0.08) ! Golgi apparatus; GO:0005773 (0.08) ! vacuole; GO:0005615 (0.08) ! extracellular space; GO:0005578 (0.08) ! proteinaceous extracellular matrix; GO:1990234 (0.07) ! transferase complex; GO:0098687 (0.07) ! chromosomal region; GO:0048471 (0.07) ! perinuclear region of cytoplasm; GO:0044354 (0.07) ! macropinosome; GO:0031252 (0.07) ! cell leading edge; GO:0030027 (0.07) ! lamellipodium; GO:0005739 (0.07) ! mitochondrion; GO:0098805 (0.06) ! whole membrane; GO:0098588 (0.06) ! bounding membrane of organelle; GO:0045111 (0.06) ! intermediate filament cytoskeleton; GO:0031941 (0.06) ! filamentous actin; GO:0016023 (0.06) ! cytoplasmic, membrane-bounded vesicle; GO:0046696 (0.05) ! lipopolysaccharide receptor complex; GO:0045121 (0.05) ! membrane raft; GO:0044454 (0.05) ! nuclear chromosome part; GO:0042383 (0.05) ! sarcolemma; GO:0031965 (0.05) ! nuclear membrane; GO:0031362 (0.05) ! anchored component of external side of plasma membrane; GO:0030133 (0.05) ! transport vesicle; GO:0019005 (0.05) ! SCF ubiquitin ligase complex; GO:0009897 (0.05) ! external side of plasma membrane; GO:0005938 (0.05) ! cell cortex; GO:0005741 (0.05) ! mitochondrial outer membrane; GO:0000775 (0.05) ! chromosome, centromeric region; GO:0045169 (0.04) ! fusome; GO:0044463 (0.04) ! cell projection part; GO:0043596 (0.03) ! nuclear replication fork; GO:0042555 (0.03) ! MCM complex; GO:0035101 (0.03) ! FACT complex; GO:0005930 (0.03) ! axoneme; GO:0005662 (0.03) ! DNA replication factor A complex; GO:0098590 (0.02) ! plasma membrane region; GO:0072559 (0.02) ! NLRP3 inflammasome complex; GO:0043025 (0.02) ! neuronal cell body; GO:0030054 (0.02) ! cell junction; GO:0005968 (0.02) ! Rab-protein geranylgeranyltransferase complex; GO:0000784 (0.02) ! nuclear chromosome, telomeric region; GO:0045335 (0.01) ! phagocytic vesicle; GO:0042585 (0.01) ! germinal vesicle; GO:0042025 (0.01) ! host cell nucleus; GO:0031967 (0.01) ! organelle envelope; GO:0031933 (0.01) ! telomeric heterochromatin; GO:0031234 (0.01) ! extrinsic component of cytoplasmic side of plasma membrane; GO:0030529 (0.01) ! intracellular ribonucleoprotein complex; GO:0030016 (0.01) ! myofibril; GO:0030014 (0.01) ! CCR4-NOT complex; GO:0016323 (0.01) ! basolateral plasma membrane; GO:0015629 (0.01) ! actin cytoskeleton; GO:0009507 (0.01) ! chloroplast; GO:0009506 (0.01) ! plasmodesma; GO:0009328 (0.01) ! phenylalanine-tRNA ligase complex; GO:0008290 (0.01) ! F-actin capping protein complex; GO:0008180 (0.01) ! COP9 signalosome; GO:0005927 (0.01) ! muscle tendon junction; GO:0005903 (0.01) ! brush border; GO:0005764 (0.01) ! lysosome; GO:0005730 (0.01) ! nucleolus; GO:0005721 (0.01) ! pericentric heterochromatin; GO:0005664 (0.01) ! nuclear origin of replication recognition complex; GO:0001726 (0.01) ! ruffle; GO:0000776 (0.01) ! kinetochore 2 16441577-16492153 (17p11.2) MGTRQTKGSLAERASPGAAPGPRRERPDFWASLLLRAGDKAGRAGAGMPPYHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDALGAMEKLCRQLTYHLSPHSQWRRHRGLVKRKPQACLKAVLAGSPPDNTVDLSGIPLTSRDLERVTSYLQRCGEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRAVLRDLTDILKDPSKFPNVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILELGEGPGSGEEVREGTVGQEDPGGGPVAPAEDHHEGKETVAAAQT SPECC1 Cytospin-B CYTSB_HUMAN (Q5M775-1) GO:0008092 (0.53) ! cytoskeletal protein binding; GO:0046983 (0.45) ! protein dimerization activity; GO:0042802 (0.45) ! identical protein binding; GO:0019899 (0.45) ! enzyme binding; GO:0003779 (0.43) ! actin binding; GO:0042805 (0.42) ! actinin binding; GO:0005198 (0.41) ! structural molecule activity; GO:1901363 (0.40) ! heterocyclic compound binding; GO:0097367 (0.40) ! carbohydrate derivative binding; GO:0097159 (0.40) ! organic cyclic compound binding; GO:0032403 (0.40) ! protein complex binding; GO:0003824 (0.39) ! catalytic activity; GO:0051015 (0.38) ! actin filament binding; GO:0044389 (0.38) ! ubiquitin-like protein ligase binding; GO:0003676 (0.38) ! nucleic acid binding; GO:0001948 (0.38) ! glycoprotein binding; GO:0045296 (0.37) ! cadherin binding; GO:0017166 (0.36) ! vinculin binding; GO:0003723 (0.35) ! RNA binding; GO:0008013 (0.32) ! beta-catenin binding; GO:0016787 (0.30) ! hydrolase activity; GO:0017111 (0.28) ! nucleoside-triphosphatase activity; GO:0016887 (0.27) ! ATPase activity; GO:0003774 (0.25) ! motor activity; GO:0003777 (0.23) ! microtubule motor activity; GO:0042803 (0.10) ! protein homodimerization activity; GO:0016740 (0.09) ! transferase activity; GO:1990939 (0.08) ! ATP-dependent microtubule motor activity; GO:0015631 (0.07) ! tubulin binding; GO:0008574 (0.07) ! ATP-dependent microtubule motor activity, plus-end-directed; GO:0051393 (0.06) ! alpha-actinin binding; GO:0016301 (0.06) ! kinase activity; GO:0008017 (0.06) ! microtubule binding; GO:0098772 (0.05) ! molecular function regulator; GO:0051020 (0.05) ! GTPase binding; GO:0019901 (0.05) ! protein kinase binding; GO:0004672 (0.05) ! protein kinase activity; GO:0003677 (0.05) ! DNA binding; GO:0030695 (0.04) ! GTPase regulator activity; GO:0017137 (0.04) ! Rab GTPase binding; GO:0005215 (0.04) ! transporter activity; GO:0004674 (0.04) ! protein serine/threonine kinase activity; GO:0043565 (0.03) ! sequence-specific DNA binding; GO:0042623 (0.03) ! ATPase activity, coupled; GO:0036094 (0.03) ! small molecule binding; GO:0019904 (0.03) ! protein domain specific binding; GO:0005487 (0.03) ! nucleocytoplasmic transporter activity; GO:0005200 (0.03) ! structural constituent of cytoskeleton; GO:0005102 (0.03) ! receptor binding; GO:0005096 (0.03) ! GTPase activator activity; GO:0004702 (0.03) ! receptor signaling protein serine/threonine kinase activity; GO:0004518 (0.03) ! nuclease activity; GO:0060090 (0.02) ! binding, bridging; GO:0051880 (0.02) ! G-quadruplex DNA binding; GO:0044822 (0.02) ! poly(A) RNA binding; GO:0043047 (0.02) ! single-stranded telomeric DNA binding; GO:0032182 (0.02) ! ubiquitin-like protein binding; GO:0019894 (0.02) ! kinesin binding; GO:0008408 (0.02) ! 3'-5' exonuclease activity; GO:0008289 (0.02) ! lipid binding; GO:0008134 (0.02) ! transcription factor binding; GO:0004842 (0.02) ! ubiquitin-protein transferase activity; GO:0004017 (0.02) ! adenylate kinase activity; GO:0004003 (0.02) ! ATP-dependent DNA helicase activity; GO:0003691 (0.02) ! double-stranded telomeric DNA binding; GO:0001882 (0.02) ! nucleoside binding; GO:0000166 (0.02) ! nucleotide binding; GO:0000146 (0.02) ! microfilament motor activity; GO:0000014 (0.02) ! single-stranded DNA endodeoxyribonuclease activity; GO:1901981 (0.01) ! phosphatidylinositol phosphate binding; GO:0098641 (0.01) ! cadherin binding involved in cell-cell adhesion; GO:0071949 (0.01) ! FAD binding; GO:0070530 (0.01) ! K63-linked polyubiquitin binding; GO:0070491 (0.01) ! repressing transcription factor binding; GO:0048487 (0.01) ! beta-tubulin binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0046872 (0.01) ! metal ion binding; GO:0046332 (0.01) ! SMAD binding; GO:0045502 (0.01) ! dynein binding; GO:0044325 (0.01) ! ion channel binding; GO:0035256 (0.01) ! G-protein coupled glutamate receptor binding; GO:0031625 (0.01) ! ubiquitin protein ligase binding; GO:0030898 (0.01) ! actin-dependent ATPase activity; GO:0030674 (0.01) ! protein binding, bridging; GO:0030507 (0.01) ! spectrin binding; GO:0030506 (0.01) ! ankyrin binding; GO:0030374 (0.01) ! ligand-dependent nuclear receptor transcription coactivator activity; GO:0030159 (0.01) ! receptor signaling complex scaffold activity; GO:0019902 (0.01) ! phosphatase binding; GO:0017056 (0.01) ! structural constituent of nuclear pore; GO:0017048 (0.01) ! Rho GTPase binding; GO:0017022 (0.01) ! myosin binding; GO:0016709 (0.01) ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; GO:0008565 (0.01) ! protein transporter activity; GO:0008432 (0.01) ! JUN kinase binding; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008081 (0.01) ! phosphoric diester hydrolase activity; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005540 (0.01) ! hyaluronic acid binding; GO:0005528 (0.01) ! FK506 binding; GO:0005524 (0.01) ! ATP binding; GO:0005516 (0.01) ! calmodulin binding; GO:0005178 (0.01) ! integrin binding; GO:0005088 (0.01) ! Ras guanyl-nucleotide exchange factor activity; GO:0005078 (0.01) ! MAP-kinase scaffold activity; GO:0004872 (0.01) ! receptor activity; GO:0004620 (0.01) ! phospholipase activity; GO:0004526 (0.01) ! ribonuclease P activity; GO:0003755 (0.01) ! peptidyl-prolyl cis-trans isomerase activity; GO:0003700 (0.01) ! transcription factor activity, sequence-specific DNA binding; GO:0003682 (0.01) ! chromatin binding; GO:0002039 (0.01) ! p53 binding; GO:0000977 (0.01) ! RNA polymerase II regulatory region sequence-specific DNA binding GO:0009987 (0.84) ! cellular process; GO:0044699 (0.82) ! single-organism process; GO:0044763 (0.74) ! single-organism cellular process; GO:0016043 (0.67) ! cellular component organization; GO:0032502 (0.62) ! developmental process; GO:0044767 (0.60) ! single-organism developmental process; GO:0006996 (0.55) ! organelle organization; GO:0065007 (0.51) ! biological regulation; GO:0048856 (0.51) ! anatomical structure development; GO:1902589 (0.49) ! single-organism organelle organization; GO:0050789 (0.48) ! regulation of biological process; GO:0007010 (0.48) ! cytoskeleton organization; GO:0050794 (0.47) ! regulation of cellular process; GO:0048869 (0.46) ! cellular developmental process; GO:0051179 (0.45) ! localization; GO:0006928 (0.43) ! movement of cell or subcellular component; GO:0030029 (0.42) ! actin filament-based process; GO:0009653 (0.42) ! anatomical structure morphogenesis; GO:0030036 (0.41) ! actin cytoskeleton organization; GO:0051641 (0.39) ! cellular localization; GO:0022607 (0.37) ! cellular component assembly; GO:0048518 (0.34) ! positive regulation of biological process; GO:0030030 (0.34) ! cell projection organization; GO:0048522 (0.33) ! positive regulation of cellular process; GO:0008104 (0.33) ! protein localization; GO:0048519 (0.32) ! negative regulation of biological process; GO:0032989 (0.32) ! cellular component morphogenesis; GO:0032879 (0.32) ! regulation of localization; GO:0009888 (0.32) ! tissue development; GO:0048523 (0.31) ! negative regulation of cellular process; GO:0048513 (0.31) ! animal organ development; GO:0040011 (0.31) ! locomotion; GO:0048870 (0.30) ! cell motility; GO:0048858 (0.30) ! cell projection morphogenesis; GO:0022414 (0.30) ! reproductive process; GO:0060429 (0.29) ! epithelium development; GO:0051239 (0.29) ! regulation of multicellular organismal process; GO:0050896 (0.29) ! response to stimulus; GO:0050793 (0.29) ! regulation of developmental process; GO:0040012 (0.29) ! regulation of locomotion; GO:0034613 (0.29) ! cellular protein localization; GO:0034330 (0.29) ! cell junction organization; GO:0030031 (0.29) ! cell projection assembly; GO:0016477 (0.29) ! cell migration; GO:0007409 (0.29) ! axonogenesis; GO:0007155 (0.29) ! cell adhesion; GO:2000145 (0.28) ! regulation of cell motility; GO:0048729 (0.28) ! tissue morphogenesis; GO:0048583 (0.28) ! regulation of response to stimulus; GO:0043933 (0.28) ! macromolecular complex subunit organization; GO:0034332 (0.28) ! adherens junction organization; GO:0023051 (0.28) ! regulation of signaling; GO:0010646 (0.28) ! regulation of cell communication; GO:2000026 (0.27) ! regulation of multicellular organismal development; GO:0071822 (0.27) ! protein complex subunit organization; GO:0060284 (0.27) ! regulation of cell development; GO:0048589 (0.27) ! developmental growth; GO:0044702 (0.27) ! single organism reproductive process; GO:0016337 (0.27) ! single organismal cell-cell adhesion; GO:0009966 (0.27) ! regulation of signal transduction; GO:0006950 (0.27) ! response to stress; GO:1990138 (0.26) ! neuron projection extension; GO:0097581 (0.26) ! lamellipodium organization; GO:0051716 (0.26) ! cellular response to stimulus; GO:0050767 (0.26) ! regulation of neurogenesis; GO:0034109 (0.26) ! homotypic cell-cell adhesion; GO:0030168 (0.26) ! platelet activation; GO:0006461 (0.26) ! protein complex assembly; GO:0003006 (0.26) ! developmental process involved in reproduction; GO:0033554 (0.25) ! cellular response to stress; GO:0009967 (0.25) ! positive regulation of signal transduction; GO:0009887 (0.25) ! organ morphogenesis; GO:1901701 (0.24) ! cellular response to oxygen-containing compound; GO:0071495 (0.24) ! cellular response to endogenous stimulus; GO:0071310 (0.24) ! cellular response to organic substance; GO:0051271 (0.24) ! negative regulation of cellular component movement; GO:0051259 (0.24) ! protein oligomerization; GO:0051241 (0.24) ! negative regulation of multicellular organismal process; GO:0051093 (0.24) ! negative regulation of developmental process; GO:0042981 (0.24) ! regulation of apoptotic process; GO:0042127 (0.24) ! regulation of cell proliferation; GO:0031175 (0.24) ! neuron projection development; GO:0009968 (0.24) ! negative regulation of signal transduction; GO:0009611 (0.24) ! response to wounding; GO:0007043 (0.24) ! cell-cell junction assembly; GO:0007017 (0.24) ! microtubule-based process; GO:2001239 (0.23) ! regulation of extrinsic apoptotic signaling pathway in absence of ligand; GO:2001238 (0.23) ! positive regulation of extrinsic apoptotic signaling pathway; GO:2001237 (0.23) ! negative regulation of extrinsic apoptotic signaling pathway; GO:2001044 (0.23) ! regulation of integrin-mediated signaling pathway; GO:2000647 (0.23) ! negative regulation of stem cell proliferation; GO:2000178 (0.23) ! negative regulation of neural precursor cell proliferation; GO:1902692 (0.23) ! regulation of neuroblast proliferation; GO:1901099 (0.23) ! negative regulation of signal transduction in absence of ligand; GO:0097306 (0.23) ! cellular response to alcohol; GO:0071680 (0.23) ! response to indole-3-methanol; GO:0071417 (0.23) ! cellular response to organonitrogen compound; GO:0071407 (0.23) ! cellular response to organic cyclic compound; GO:0050768 (0.23) ! negative regulation of neurogenesis; GO:0048678 (0.23) ! response to axon injury; GO:0046546 (0.23) ! development of primary male sexual characteristics; GO:0042476 (0.23) ! odontogenesis; GO:0040013 (0.23) ! negative regulation of locomotion; GO:0031102 (0.23) ! neuron projection regeneration; GO:0022602 (0.23) ! ovulation cycle process; GO:0008589 (0.23) ! regulation of smoothened signaling pathway; GO:0008585 (0.23) ! female gonad development; GO:0090136 (0.22) ! epithelial cell-cell adhesion; GO:0051234 (0.22) ! establishment of localization; GO:0043297 (0.22) ! apical junction assembly; GO:0031032 (0.18) ! actomyosin structure organization; GO:0006810 (0.18) ! transport; GO:0048468 (0.17) ! cell development; GO:0045214 (0.16) ! sarcomere organization; GO:0051649 (0.15) ! establishment of localization in cell; GO:0007018 (0.15) ! microtubule-based movement; GO:0055001 (0.14) ! muscle cell development; GO:0032501 (0.14) ! multicellular organismal process; GO:0051128 (0.13) ! regulation of cellular component organization; GO:0048741 (0.13) ! skeletal muscle fiber development; GO:0065008 (0.12) ! regulation of biological quality; GO:0022402 (0.12) ! cell cycle process; GO:0046907 (0.11) ! intracellular transport; GO:0044707 (0.11) ! single-multicellular organism process; GO:0044237 (0.11) ! cellular metabolic process; GO:0033043 (0.10) ! regulation of organelle organization; GO:0000226 (0.10) ! microtubule cytoskeleton organization; GO:1902578 (0.09) ! single-organism localization; GO:0080090 (0.09) ! regulation of primary metabolic process; GO:0048646 (0.09) ! anatomical structure formation involved in morphogenesis; GO:0044238 (0.09) ! primary metabolic process; GO:0043170 (0.09) ! macromolecule metabolic process; GO:0031323 (0.09) ! regulation of cellular metabolic process; GO:0016192 (0.09) ! vesicle-mediated transport; GO:1903047 (0.08) ! mitotic cell cycle process; GO:0060255 (0.08) ! regulation of macromolecule metabolic process; GO:0044260 (0.08) ! cellular macromolecule metabolic process; GO:0051640 (0.07) ! organelle localization; GO:0051493 (0.07) ! regulation of cytoskeleton organization; GO:0044765 (0.07) ! single-organism transport; GO:1902580 (0.06) ! single-organism cellular localization; GO:0071702 (0.06) ! organic substance transport; GO:0070925 (0.06) ! organelle assembly; GO:0060325 (0.06) ! face morphogenesis; GO:0051656 (0.06) ! establishment of organelle localization; GO:0051240 (0.06) ! positive regulation of multicellular organismal process; GO:0051130 (0.06) ! positive regulation of cellular component organization; GO:0045184 (0.06) ! establishment of protein localization; GO:0032886 (0.06) ! regulation of microtubule-based process; GO:0010639 (0.06) ! negative regulation of organelle organization; GO:0007165 (0.06) ! signal transduction; GO:0007015 (0.06) ! actin filament organization; GO:1901879 (0.05) ! regulation of protein depolymerization; GO:0070507 (0.05) ! regulation of microtubule cytoskeleton organization; GO:0065009 (0.05) ! regulation of molecular function; GO:0061061 (0.05) ! muscle structure development; GO:0061024 (0.05) ! membrane organization; GO:0051246 (0.05) ! regulation of protein metabolic process; GO:0051171 (0.05) ! regulation of nitrogen compound metabolic process; GO:0051094 (0.05) ! positive regulation of developmental process; GO:0051049 (0.05) ! regulation of transport; GO:0044087 (0.05) ! regulation of cellular component biogenesis; GO:0040008 (0.05) ! regulation of growth; GO:0034641 (0.05) ! cellular nitrogen compound metabolic process; GO:0030705 (0.05) ! cytoskeleton-dependent intracellular transport; GO:0022604 (0.05) ! regulation of cell morphogenesis; GO:0019538 (0.05) ! protein metabolic process; GO:0015031 (0.05) ! protein transport; GO:0010927 (0.05) ! cellular component assembly involved in morphogenesis; GO:0009893 (0.05) ! positive regulation of metabolic process; GO:0009886 (0.05) ! post-embryonic morphogenesis; GO:2000112 (0.04) ! regulation of cellular macromolecule biosynthetic process; GO:1903506 (0.04) ! regulation of nucleic acid-templated transcription; GO:1902582 (0.04) ! single-organism intracellular transport; GO:0090304 (0.04) ! nucleic acid metabolic process; GO:0051726 (0.04) ! regulation of cell cycle; GO:0050790 (0.04) ! regulation of catalytic activity; GO:0048639 (0.04) ! positive regulation of developmental growth; GO:0044802 (0.04) ! single-organism membrane organization; GO:0044710 (0.04) ! single-organism metabolic process; GO:0044089 (0.04) ! positive regulation of cellular component biogenesis; GO:0042325 (0.04) ! regulation of phosphorylation; GO:0035239 (0.04) ! tube morphogenesis; GO:0032535 (0.04) ! regulation of cellular component size; GO:0031399 (0.04) ! regulation of protein modification process; GO:0031325 (0.04) ! positive regulation of cellular metabolic process; GO:0010976 (0.04) ! positive regulation of neuron projection development; GO:0010769 (0.04) ! regulation of cell morphogenesis involved in differentiation; GO:0010604 (0.04) ! positive regulation of macromolecule metabolic process; GO:0010468 (0.04) ! regulation of gene expression; GO:0007267 (0.04) ! cell-cell signaling; GO:0007026 (0.04) ! negative regulation of microtubule depolymerization; GO:0006886 (0.04) ! intracellular protein transport; GO:0006464 (0.04) ! cellular protein modification process; GO:0003008 (0.04) ! system process; GO:0001578 (0.04) ! microtubule bundle formation; GO:1903046 (0.03) ! meiotic cell cycle process; GO:1902531 (0.03) ! regulation of intracellular signal transduction; GO:0060341 (0.03) ! regulation of cellular localization; GO:0051491 (0.03) ! positive regulation of filopodium assembly; GO:0051050 (0.03) ! positive regulation of transport; GO:0048813 (0.03) ! dendrite morphogenesis; GO:0048598 (0.03) ! embryonic morphogenesis; GO:0048193 (0.03) ! Golgi vesicle transport; GO:0045773 (0.03) ! positive regulation of axon extension; GO:0044093 (0.03) ! positive regulation of molecular function; GO:0035556 (0.03) ! intracellular signal transduction; GO:0035149 (0.03) ! lumen formation, open tracheal system; GO:0035147 (0.03) ! branch fusion, open tracheal system; GO:0033365 (0.03) ! protein localization to organelle; GO:0032956 (0.03) ! regulation of actin cytoskeleton organization; GO:0032270 (0.03) ! positive regulation of cellular protein metabolic process; GO:0031324 (0.03) ! negative regulation of cellular metabolic process; GO:0030716 (0.03) ! oocyte fate determination; GO:0030154 (0.03) ! cell differentiation; GO:0022412 (0.03) ! cellular process involved in reproduction in multicellular organism; GO:0016319 (0.03) ! mushroom body development; GO:0016310 (0.03) ! phosphorylation; GO:0016204 (0.03) ! determination of muscle attachment site; GO:0016203 (0.03) ! muscle attachment; GO:0016199 (0.03) ! axon midline choice point recognition; GO:0010564 (0.03) ! regulation of cell cycle process; GO:0007610 (0.03) ! behavior; GO:0007527 (0.03) ! adult somatic muscle development; GO:0007498 (0.03) ! mesoderm development; GO:0007475 (0.03) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.03) ! open tracheal system development; GO:0007423 (0.03) ! sensory organ development; GO:0007034 (0.03) ! vacuolar transport; GO:0007009 (0.03) ! plasma membrane organization; GO:0006897 (0.03) ! endocytosis; GO:0006355 (0.03) ! regulation of transcription, DNA-templated; GO:0001932 (0.03) ! regulation of protein phosphorylation; GO:1903827 (0.02) ! regulation of cellular protein localization; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:0090150 (0.02) ! establishment of protein localization to membrane; GO:0070201 (0.02) ! regulation of establishment of protein localization; GO:0060627 (0.02) ! regulation of vesicle-mediated transport; GO:0060249 (0.02) ! anatomical structure homeostasis; GO:0055114 (0.02) ! oxidation-reduction process; GO:0051983 (0.02) ! regulation of chromosome segregation; GO:0051783 (0.02) ! regulation of nuclear division; GO:0051297 (0.02) ! centrosome organization; GO:0051294 (0.02) ! establishment of spindle orientation; GO:0051276 (0.02) ! chromosome organization; GO:0048802 (0.02) ! notum morphogenesis; GO:0048734 (0.02) ! proboscis morphogenesis; GO:0045935 (0.02) ! positive regulation of nucleobase-containing compound metabolic process; GO:0045934 (0.02) ! negative regulation of nucleobase-containing compound metabolic process; GO:0045786 (0.02) ! negative regulation of cell cycle; GO:0044708 (0.02) ! single-organism behavior; GO:0044271 (0.02) ! cellular nitrogen compound biosynthetic process; GO:0043623 (0.02) ! cellular protein complex assembly; GO:0043087 (0.02) ! regulation of GTPase activity; GO:0043085 (0.02) ! positive regulation of catalytic activity; GO:0042384 (0.02) ! cilium assembly; GO:0040023 (0.02) ! establishment of nucleus localization; GO:0035220 (0.02) ! wing disc development; GO:0034645 (0.02) ! cellular macromolecule biosynthetic process; GO:0034453 (0.02) ! microtubule anchoring; GO:0034333 (0.02) ! adherens junction assembly; GO:0033044 (0.02) ! regulation of chromosome organization; GO:0030834 (0.02) ! regulation of actin filament depolymerization; GO:0030431 (0.02) ! sleep; GO:0030334 (0.02) ! regulation of cell migration; GO:0030048 (0.02) ! actin filament-based movement; GO:0030042 (0.02) ! actin filament depolymerization; GO:0016197 (0.02) ! endosomal transport; GO:0010970 (0.02) ! establishment of localization by movement along microtubule; GO:0010959 (0.02) ! regulation of metal ion transport; GO:0010810 (0.02) ! regulation of cell-substrate adhesion; GO:0010638 (0.02) ! positive regulation of organelle organization; GO:0010628 (0.02) ! positive regulation of gene expression; GO:0010605 (0.02) ! negative regulation of macromolecule metabolic process; GO:0009628 (0.02) ! response to abiotic stimulus; GO:0009605 (0.02) ! response to external stimulus; GO:0007626 (0.02) ! locomotory behavior; GO:0007600 (0.02) ! sensory perception; GO:0007519 (0.02) ! skeletal muscle tissue development; GO:0007517 (0.02) ! muscle organ development; GO:0007507 (0.02) ! heart development; GO:0007411 (0.02) ! axon guidance; GO:0007389 (0.02) ! pattern specification process; GO:0007346 (0.02) ! regulation of mitotic cell cycle; GO:0007275 (0.02) ! multicellular organism development; GO:0007166 (0.02) ! cell surface receptor signaling pathway; GO:0007131 (0.02) ! reciprocal meiotic recombination; GO:0007059 (0.02) ! chromosome segregation; GO:0007051 (0.02) ! spindle organization; GO:0007030 (0.02) ! Golgi organization; GO:0007020 (0.02) ! microtubule nucleation; GO:0006974 (0.02) ! cellular response to DNA damage stimulus; GO:0006936 (0.02) ! muscle contraction; GO:0006913 (0.02) ! nucleocytoplasmic transport; GO:0006468 (0.02) ! protein phosphorylation; GO:0006357 (0.02) ! regulation of transcription from RNA polymerase II promoter; GO:0003341 (0.02) ! cilium movement; GO:0002064 (0.02) ! epithelial cell development; GO:0002009 (0.02) ! morphogenesis of an epithelium; GO:0001934 (0.02) ! positive regulation of protein phosphorylation; GO:0000904 (0.02) ! cell morphogenesis involved in differentiation; GO:0000281 (0.02) ! mitotic cytokinesis; GO:0000075 (0.02) ! cell cycle checkpoint; GO:2001257 (0.01) ! regulation of cation channel activity; GO:2000649 (0.01) ! regulation of sodium ion transmembrane transporter activity; GO:1990126 (0.01) ! retrograde transport, endosome to plasma membrane; GO:1904064 (0.01) ! positive regulation of cation transmembrane transport; GO:1903533 (0.01) ! regulation of protein targeting; GO:1903530 (0.01) ! regulation of secretion by cell; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1902481 (0.01) ! gamma-tubulin complex assembly; GO:1902115 (0.01) ! regulation of organelle assembly; GO:1900076 (0.01) ! regulation of cellular response to insulin stimulus; GO:0099643 (0.01) ! signal release from synapse; GO:0099531 (0.01) ! presynaptic process involved in chemical synaptic transmission; GO:0099515 (0.01) ! actin filament-based transport; GO:0098840 (0.01) ! protein transport along microtubule; GO:0097320 (0.01) ! membrane tubulation; GO:0097095 (0.01) ! frontonasal suture morphogenesis; GO:0090630 (0.01) ! activation of GTPase activity; GO:0090316 (0.01) ! positive regulation of intracellular protein transport; GO:0090307 (0.01) ! mitotic spindle assembly; GO:0090305 (0.01) ! nucleic acid phosphodiester bond hydrolysis; GO:0090287 (0.01) ! regulation of cellular response to growth factor stimulus; GO:0090286 (0.01) ! cytoskeletal anchoring at nuclear membrane; GO:0071496 (0.01) ! cellular response to external stimulus; GO:0070830 (0.01) ! bicellular tight junction assembly; GO:0070192 (0.01) ! chromosome organization involved in meiotic cell cycle; GO:0061337 (0.01) ! cardiac conduction; GO:0060361 (0.01) ! flight; GO:0060287 (0.01) ! epithelial cilium movement involved in determination of left/right asymmetry; GO:0060285 (0.01) ! cilium-dependent cell motility; GO:0060271 (0.01) ! cilium morphogenesis; GO:0051893 (0.01) ! regulation of focal adhesion assembly; GO:0051704 (0.01) ! multi-organism process; GO:0051646 (0.01) ! mitochondrion localization; GO:0051643 (0.01) ! endoplasmic reticulum localization; GO:0051642 (0.01) ! centrosome localization; GO:0051495 (0.01) ! positive regulation of cytoskeleton organization; GO:0051315 (0.01) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051310 (0.01) ! metaphase plate congression; GO:0051260 (0.01) ! protein homooligomerization; GO:0051056 (0.01) ! regulation of small GTPase mediated signal transduction; GO:0051051 (0.01) ! negative regulation of transport; GO:0051017 (0.01) ! actin filament bundle assembly; GO:0050848 (0.01) ! regulation of calcium-mediated signaling; GO:0050808 (0.01) ! synapse organization; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0048666 (0.01) ! neuron development; GO:0048568 (0.01) ! embryonic organ development; GO:0048384 (0.01) ! retinoic acid receptor signaling pathway; GO:0048278 (0.01) ! vesicle docking; GO:0048041 (0.01) ! focal adhesion assembly; GO:0047496 (0.01) ! vesicle transport along microtubule; GO:0046716 (0.01) ! muscle cell cellular homeostasis; GO:0046622 (0.01) ! positive regulation of organ growth; GO:0046605 (0.01) ! regulation of centrosome cycle; GO:0046330 (0.01) ! positive regulation of JNK cascade; GO:0045862 (0.01) ! positive regulation of proteolysis; GO:0045793 (0.01) ! positive regulation of cell size; GO:0045787 (0.01) ! positive regulation of cell cycle; GO:0045747 (0.01) ! positive regulation of Notch signaling pathway; GO:0045186 (0.01) ! zonula adherens assembly; GO:0045162 (0.01) ! clustering of voltage-gated sodium channels; GO:0045104 (0.01) ! intermediate filament cytoskeleton organization; GO:0045055 (0.01) ! regulated exocytosis; GO:0045035 (0.01) ! sensory organ precursor cell division; GO:0044772 (0.01) ! mitotic cell cycle phase transition; GO:0044351 (0.01) ! macropinocytosis; GO:0044265 (0.01) ! cellular macromolecule catabolic process; GO:0043406 (0.01) ! positive regulation of MAP kinase activity; GO:0043254 (0.01) ! regulation of protein complex assembly; GO:0043122 (0.01) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043086 (0.01) ! negative regulation of catalytic activity; GO:0043009 (0.01) ! chordate embryonic development; GO:0043001 (0.01) ! Golgi to plasma membrane protein transport; GO:0042391 (0.01) ! regulation of membrane potential; GO:0042073 (0.01) ! intraciliary transport; GO:0042060 (0.01) ! wound healing; GO:0040018 (0.01) ! positive regulation of multicellular organism growth; GO:0036159 (0.01) ! inner dynein arm assembly; GO:0036010 (0.01) ! protein localization to endosome; GO:0035786 (0.01) ! protein complex oligomerization; GO:0035357 (0.01) ! peroxisome proliferator activated receptor signaling pathway; GO:0035150 (0.01) ! regulation of tube size; GO:0035082 (0.01) ! axoneme assembly; GO:0034454 (0.01) ! microtubule anchoring at centrosome; GO:0034446 (0.01) ! substrate adhesion-dependent cell spreading; GO:0033135 (0.01) ! regulation of peptidyl-serine phosphorylation; GO:0032509 (0.01) ! endosome transport via multivesicular body sorting pathway; GO:0032508 (0.01) ! DNA duplex unwinding; GO:0032506 (0.01) ! cytokinetic process; GO:0032458 (0.01) ! slow endocytic recycling; GO:0032414 (0.01) ! positive regulation of ion transmembrane transporter activity; GO:0032147 (0.01) ! activation of protein kinase activity; GO:0031667 (0.01) ! response to nutrient levels; GO:0031581 (0.01) ! hemidesmosome assembly; GO:0031532 (0.01) ! actin cytoskeleton reorganization; GO:0031338 (0.01) ! regulation of vesicle fusion; GO:0031034 (0.01) ! myosin filament assembly; GO:0030866 (0.01) ! cortical actin cytoskeleton organization; GO:0030855 (0.01) ! epithelial cell differentiation; GO:0030835 (0.01) ! negative regulation of actin filament depolymerization; GO:0030707 (0.01) ! ovarian follicle cell development; GO:0030335 (0.01) ! positive regulation of cell migration; GO:0030239 (0.01) ! myofibril assembly; GO:0030198 (0.01) ! extracellular matrix organization; GO:0030111 (0.01) ! regulation of Wnt signaling pathway; GO:0030097 (0.01) ! hemopoiesis; GO:0030049 (0.01) ! muscle filament sliding; GO:0022008 (0.01) ! neurogenesis; GO:0021952 (0.01) ! central nervous system projection neuron axonogenesis; GO:0019722 (0.01) ! calcium-mediated signaling; GO:0019417 (0.01) ! sulfur oxidation; GO:0019226 (0.01) ! transmission of nerve impulse; GO:0018193 (0.01) ! peptidyl-amino acid modification; GO:0016567 (0.01) ! protein ubiquitination; GO:0016233 (0.01) ! telomere capping; GO:0016070 (0.01) ! RNA metabolic process; GO:0010797 (0.01) ! regulation of multivesicular body size involved in endosome transport; GO:0010735 (0.01) ! positive regulation of transcription via serum response element binding; GO:0010632 (0.01) ! regulation of epithelial cell migration; GO:0010459 (0.01) ! negative regulation of heart rate; GO:0010172 (0.01) ! embryonic body morphogenesis; GO:0009904 (0.01) ! chloroplast accumulation movement; GO:0009903 (0.01) ! chloroplast avoidance movement; GO:0009896 (0.01) ! positive regulation of catabolic process; GO:0009607 (0.01) ! response to biotic stimulus; GO:0009314 (0.01) ! response to radiation; GO:0008360 (0.01) ! regulation of cell shape; GO:0008335 (0.01) ! female germline ring canal stabilization; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0007628 (0.01) ! adult walking behavior; GO:0007605 (0.01) ! sensory perception of sound; GO:0007523 (0.01) ! larval visceral muscle development; GO:0007309 (0.01) ! oocyte axis specification; GO:0007303 (0.01) ! cytoplasmic transport, nurse cell to oocyte; GO:0007281 (0.01) ! germ cell development; GO:0007276 (0.01) ! gamete generation; GO:0007268 (0.01) ! chemical synaptic transmission; GO:0007169 (0.01) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007163 (0.01) ! establishment or maintenance of cell polarity; GO:0007099 (0.01) ! centriole replication; GO:0007097 (0.01) ! nuclear migration; GO:0007094 (0.01) ! mitotic spindle assembly checkpoint; GO:0007052 (0.01) ! mitotic spindle organization; GO:0007041 (0.01) ! lysosomal transport; GO:0007004 (0.01) ! telomere maintenance via telomerase; GO:0006997 (0.01) ! nucleus organization; GO:0006942 (0.01) ! regulation of striated muscle contraction; GO:0006941 (0.01) ! striated muscle contraction; GO:0006935 (0.01) ! chemotaxis; GO:0006898 (0.01) ! receptor-mediated endocytosis; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006612 (0.01) ! protein targeting to membrane; GO:0006606 (0.01) ! protein import into nucleus; GO:0006508 (0.01) ! proteolysis; GO:0006412 (0.01) ! translation; GO:0006405 (0.01) ! RNA export from nucleus; GO:0006325 (0.01) ! chromatin organization; GO:0003198 (0.01) ! epithelial to mesenchymal transition involved in endocardial cushion formation; GO:0003013 (0.01) ! circulatory system process; GO:0002682 (0.01) ! regulation of immune system process; GO:0002376 (0.01) ! immune system process; GO:0002119 (0.01) ! nematode larval development; GO:0001954 (0.01) ! positive regulation of cell-matrix adhesion; GO:0001947 (0.01) ! heart looping; GO:0001933 (0.01) ! negative regulation of protein phosphorylation; GO:0001817 (0.01) ! regulation of cytokine production; GO:0001654 (0.01) ! eye development; GO:0001505 (0.01) ! regulation of neurotransmitter levels; GO:0000742 (0.01) ! karyogamy involved in conjugation with cellular fusion; GO:0000724 (0.01) ! double-strand break repair via homologous recombination; GO:0000722 (0.01) ! telomere maintenance via recombination; GO:0000301 (0.01) ! retrograde transport, vesicle recycling within Golgi; GO:0000280 (0.01) ! nuclear division; GO:0000278 (0.01) ! mitotic cell cycle; GO:0000165 (0.01) ! MAPK cascade; GO:0000132 (0.01) ! establishment of mitotic spindle orientation; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter; GO:0000070 (0.01) ! mitotic sister chromatid segregation; GO:0000045 (0.01) ! autophagosome assembly; GO:0000022 (0.01) ! mitotic spindle elongation GO:0044464 (0.98) ! cell part; GO:0044424 (0.97) ! intracellular part; GO:0044422 (0.78) ! organelle part; GO:0044446 (0.76) ! intracellular organelle part; GO:0043226 (0.75) ! organelle; GO:0043229 (0.71) ! intracellular organelle; GO:0044430 (0.66) ! cytoskeletal part; GO:0044444 (0.64) ! cytoplasmic part; GO:0016020 (0.59) ! membrane; GO:0043232 (0.54) ! intracellular non-membrane-bounded organelle; GO:0044425 (0.52) ! membrane part; GO:0030054 (0.51) ! cell junction; GO:0005856 (0.51) ! cytoskeleton; GO:0005886 (0.48) ! plasma membrane; GO:0044459 (0.47) ! plasma membrane part; GO:0042995 (0.45) ! cell projection; GO:0005912 (0.45) ! adherens junction; GO:0005737 (0.42) ! cytoplasm; GO:0030055 (0.41) ! cell-substrate junction; GO:0043227 (0.40) ! membrane-bounded organelle; GO:0005924 (0.38) ! cell-substrate adherens junction; GO:0005911 (0.36) ! cell-cell junction; GO:0044449 (0.35) ! contractile fiber part; GO:0044448 (0.34) ! cell cortex part; GO:0005925 (0.34) ! focal adhesion; GO:0005913 (0.33) ! cell-cell adherens junction; GO:0043231 (0.30) ! intracellular membrane-bounded organelle; GO:0032432 (0.30) ! actin filament bundle; GO:0030027 (0.30) ! lamellipodium; GO:0042383 (0.29) ! sarcolemma; GO:0030863 (0.29) ! cortical cytoskeleton; GO:0043234 (0.28) ! protein complex; GO:0005915 (0.28) ! zonula adherens; GO:0001725 (0.28) ! stress fiber; GO:0030864 (0.27) ! cortical actin cytoskeleton; GO:1990357 (0.26) ! terminal web; GO:0090637 (0.26) ! inner dense plaque of desmosome; GO:0090636 (0.26) ! outer dense plaque of desmosome; GO:0031252 (0.26) ! cell leading edge; GO:0030486 (0.26) ! smooth muscle dense body; GO:0016328 (0.26) ! lateral plasma membrane; GO:0005923 (0.26) ! bicellular tight junction; GO:0097433 (0.25) ! dense body; GO:0005634 (0.20) ! nucleus; GO:0098590 (0.17) ! plasma membrane region; GO:0097458 (0.16) ! neuron part; GO:0044463 (0.16) ! cell projection part; GO:0031988 (0.16) ! membrane-bounded vesicle; GO:0015629 (0.15) ! actin cytoskeleton; GO:0099513 (0.14) ! polymeric cytoskeletal fiber; GO:0044421 (0.13) ! extracellular region part; GO:0070062 (0.12) ! extracellular exosome; GO:0044428 (0.11) ! nuclear part; GO:0098797 (0.09) ! plasma membrane protein complex; GO:0031090 (0.09) ! organelle membrane; GO:0005829 (0.09) ! cytosol; GO:0030175 (0.08) ! filopodium; GO:0005875 (0.08) ! microtubule associated complex; GO:0043005 (0.07) ! neuron projection; GO:0033267 (0.07) ! axon part; GO:0030427 (0.07) ! site of polarized growth; GO:0030018 (0.07) ! Z disc; GO:0005874 (0.07) ! microtubule; GO:0098588 (0.06) ! bounding membrane of organelle; GO:0045169 (0.06) ! fusome; GO:0035371 (0.06) ! microtubule plus-end; GO:0031253 (0.06) ! cell projection membrane; GO:0030426 (0.06) ! growth cone; GO:0016324 (0.06) ! apical plasma membrane; GO:0005927 (0.06) ! muscle tendon junction; GO:0005876 (0.06) ! spindle microtubule; GO:0005815 (0.06) ! microtubule organizing center; GO:0005794 (0.06) ! Golgi apparatus; GO:0098805 (0.05) ! whole membrane; GO:0044295 (0.05) ! axonal growth cone; GO:0016023 (0.05) ! cytoplasmic, membrane-bounded vesicle; GO:0008091 (0.05) ! spectrin; GO:0005654 (0.05) ! nucleoplasm; GO:0005576 (0.05) ! extracellular region; GO:0000235 (0.05) ! astral microtubule; GO:0099503 (0.04) ! secretory vesicle; GO:0048471 (0.04) ! perinuclear region of cytoplasm; GO:0045202 (0.04) ! synapse; GO:0031941 (0.04) ! filamentous actin; GO:0031256 (0.04) ! leading edge membrane; GO:0030424 (0.04) ! axon; GO:0015630 (0.04) ! microtubule cytoskeleton; GO:0005884 (0.04) ! actin filament; GO:0005635 (0.04) ! nuclear envelope; GO:0032587 (0.03) ! ruffle membrane; GO:0031965 (0.03) ! nuclear membrane; GO:0031594 (0.03) ! neuromuscular junction; GO:0030056 (0.03) ! hemidesmosome; GO:0016600 (0.03) ! flotillin complex; GO:0016342 (0.03) ! catenin complex; GO:0016323 (0.03) ! basolateral plasma membrane; GO:0016010 (0.03) ! dystrophin-associated glycoprotein complex; GO:0014704 (0.03) ! intercalated disc; GO:0009986 (0.03) ! cell surface; GO:0009925 (0.03) ! basal plasma membrane; GO:0008305 (0.03) ! integrin complex; GO:0005938 (0.03) ! cell cortex; GO:0005882 (0.03) ! intermediate filament; GO:0005871 (0.03) ! kinesin complex; GO:0005773 (0.03) ! vacuole; GO:0005623 (0.03) ! cell; GO:0005622 (0.03) ! intracellular; GO:0005615 (0.03) ! extracellular space; GO:0001726 (0.03) ! ruffle; GO:0001669 (0.03) ! acrosomal vesicle; GO:0070938 (0.02) ! contractile ring; GO:0045121 (0.02) ! membrane raft; GO:0045111 (0.02) ! intermediate filament cytoskeleton; GO:0044456 (0.02) ! synapse part; GO:0044450 (0.02) ! microtubule organizing center part; GO:0044441 (0.02) ! ciliary part; GO:0043034 (0.02) ! costamere; GO:0043025 (0.02) ! neuronal cell body; GO:0031527 (0.02) ! filopodium membrane; GO:0031143 (0.02) ! pseudopodium; GO:0030529 (0.02) ! intracellular ribonucleoprotein complex; GO:0030016 (0.02) ! myofibril; GO:0016327 (0.02) ! apicolateral plasma membrane; GO:0016234 (0.02) ! inclusion body; GO:0016021 (0.02) ! integral component of membrane; GO:0005903 (0.02) ! brush border; GO:0005865 (0.02) ! striated muscle thin filament; GO:0005789 (0.02) ! endoplasmic reticulum membrane; GO:0005783 (0.02) ! endoplasmic reticulum; GO:0005774 (0.02) ! vacuolar membrane; GO:0005768 (0.02) ! endosome; GO:0005739 (0.02) ! mitochondrion; GO:0005640 (0.02) ! nuclear outer membrane; GO:0098791 (0.01) ! Golgi subcompartment; GO:0098723 (0.01) ! skeletal muscle myofibril; GO:0097381 (0.01) ! photoreceptor disc membrane; GO:0097060 (0.01) ! synaptic membrane; GO:0070852 (0.01) ! cell body fiber; GO:0055120 (0.01) ! striated muscle dense body; GO:0055038 (0.01) ! recycling endosome membrane; GO:0055037 (0.01) ! recycling endosome; GO:0048046 (0.01) ! apoplast; GO:0045335 (0.01) ! phagocytic vesicle; GO:0045179 (0.01) ! apical cortex; GO:0044454 (0.01) ! nuclear chromosome part; GO:0043203 (0.01) ! axon hillock; GO:0043197 (0.01) ! dendritic spine; GO:0043194 (0.01) ! axon initial segment; GO:0042405 (0.01) ! nuclear inclusion body; GO:0034993 (0.01) ! LINC complex; GO:0033270 (0.01) ! paranode region of axon; GO:0033268 (0.01) ! node of Ranvier; GO:0032391 (0.01) ! photoreceptor connecting cilium; GO:0032154 (0.01) ! cleavage furrow; GO:0031981 (0.01) ! nuclear lumen; GO:0031674 (0.01) ! I band; GO:0031430 (0.01) ! M band; GO:0031371 (0.01) ! ubiquitin conjugating enzyme complex; GO:0031258 (0.01) ! lamellipodium membrane; GO:0031254 (0.01) ! cell trailing edge; GO:0031093 (0.01) ! platelet alpha granule lumen; GO:0031012 (0.01) ! extracellular matrix; GO:0030673 (0.01) ! axolemma; GO:0030017 (0.01) ! sarcomere; GO:0019898 (0.01) ! extrinsic component of membrane; GO:0016605 (0.01) ! PML body; GO:0016529 (0.01) ! sarcoplasmic reticulum; GO:0016363 (0.01) ! nuclear matrix; GO:0016235 (0.01) ! aggresome; GO:0014731 (0.01) ! spectrin-associated cytoskeleton; GO:0014069 (0.01) ! postsynaptic density; GO:0012506 (0.01) ! vesicle membrane; GO:0009570 (0.01) ! chloroplast stroma; GO:0009507 (0.01) ! chloroplast; GO:0009506 (0.01) ! plasmodesma; GO:0005934 (0.01) ! cellular bud tip; GO:0005930 (0.01) ! axoneme; GO:0005916 (0.01) ! fascia adherens; GO:0005826 (0.01) ! actomyosin contractile ring; GO:0005823 (0.01) ! central plaque of spindle pole body; GO:0005822 (0.01) ! inner plaque of spindle pole body; GO:0005814 (0.01) ! centriole; GO:0005813 (0.01) ! centrosome; GO:0005770 (0.01) ! late endosome; GO:0005743 (0.01) ! mitochondrial inner membrane; GO:0005730 (0.01) ! nucleolus; GO:0005618 (0.01) ! cell wall; GO:0001917 (0.01) ! photoreceptor inner segment; GO:0000151 (0.01) ! ubiquitin ligase complex; GO:0000139 (0.01) ! Golgi membrane GO:0016020 ! membrane; GO:0005634 ! nucleus 5 20009344-20319026 (17p11.2) High: stomach 2 (glandular cells);stomach 1 (glandular cells);epididymis (glandular cells);gallbladder (glandular cells);rectum (glandular cells);cervix, uterine (glandular cells);Medium: colon (endothelial cells; glandular cells);kidney (cells in glomeruli; cells in tubules);testis (cells in seminiferous ducts; Leydig cells);caudate (neuronal cells);tonsil (germinal center cells; non-germinal center cells);adrenal gland (glandular cells);endometrium 1 (cells in endometrial stroma; glandular cells);endometrium 2 (cells in endometrial stroma; glandular cells);salivary gland (glandular cells);smooth muscle (smooth muscle cells);duodenum (glandular cells);cerebral cortex (neuronal cells; neuropil);lymph node (germinal center cells; non-germinal center cells);placenta (trophoblastic cells);hippocampus (neuronal cells);bronchus (respiratory epithelial cells);parathyroid gland (glandular cells);urinary bladder (urothelial cells);appendix (glandular cells; lymphoid tissue);breast (glandular cells; myoepithelial cells);prostate (glandular cells);pancreas (exocrine glandular cells);cerebellum (cells in granular layer);spleen (cells in red pulp);bone marrow (hematopoietic cells);soft tissue 2 (adipocytes; peripheral nerve);small intestine (glandular cells);soft tissue 1 (chondrocytes; fibroblasts; peripheral nerve);nasopharynx (respiratory epithelial cells);lung (macrophages; pneumocytes);ovary (ovarian stroma cells);skin 1 (fibroblasts);skin 2 (epidermal cells);Low: cerebellum (cells in molecular layer);hippocampus (glial cells);fallopian tube (glandular cells);skin 1 (keratinocytes);soft tissue 2 (fibroblasts);tonsil (squamous epithelial cells);skeletal muscle (myocytes);thyroid gland (glandular cells);colon (peripheral nerve/ganglion);soft tissue 1 (adipocytes);esophagus (squamous epithelial cells);oral mucosa (squamous epithelial cells);cerebral cortex (glial cells);pancreas (islets of Langerhans); Brain - Spinal cord (cervical c-1): 19.62; Testis: 17.61; Artery - Aorta: 17.25; Artery - Coronary: 13.11; Ovary: 12.19; Brain - Frontal Cortex (BA9): 12.16; Artery - Tibial: 12.14; Brain - Cortex: 11.96; Brain - Substantia nigra: 11.32; Brain - Hippocampus: 10.12; Spleen: 9.58; Uterus: 9.46; Brain - Cerebellum: 9.33; Brain - Hypothalamus: 9.04; Adipose - Subcutaneous: 8.87; Brain - Cerebellar Hemisphere: 8.75; Nerve - Tibial: 8.36; Brain - Amygdala: 8.30; Brain - Anterior cingulate cortex (BA24): 8.08; Brain - Putamen (basal ganglia): 7.33; Brain - Caudate (basal ganglia): 7.25; Cells - EBV-transformed lymphocytes: 7.20; Brain - Nucleus accumbens (basal ganglia): 6.97; Fallopian Tube: 6.90; Colon - Transverse: 6.28; Adipose - Visceral (Omentum): 6.27; Breast - Mammary Tissue: 6.24; Stomach: 5.76; Adrenal Gland: 5.70; Pituitary: 5.08; Small Intestine - Terminal Ileum: 4.84; Lung: 4.49; Cervix - Endocervix: 4.44; Thyroid: 4.40; Prostate: 4.26; Minor Salivary Gland: 3.74; Esophagus - Mucosa: 3.60; Cervix - Ectocervix: 3.59; Esophagus - Gastroesophageal Junction: 3.15; Vagina: 2.95; Bladder: 2.83; Colon - Sigmoid: 2.51; Skin - Sun Exposed (Lower leg): 2.44; Esophagus - Muscularis: 2.42; Whole Blood: 2.18; Skin - Not Sun Exposed (Suprapubic): 2.10; Cells - Transformed fibroblasts: 1.92; Kidney - Cortex: 1.75; Pancreas: 1.33; Heart - Atrial Appendage: 1.23; Heart - Left Ventricle: 1.06; Muscle - Skeletal: 0.97; Liver: 0.23; MRSAAKPWNPAIRAGGHGPDRVRPLPAASSGMKSSKSSTSLAFESRLSRLKRASSEDTLNKPGSTAASGVVRLKKTATAGAISELTESRLRSGTGAFTTTKRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTPTPTKHLRTPSTKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSELKKYKEKRTLNAEGTDALGPNVDGTSVSPGDTEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIYLEHSPNSEGAASHTGDSSCPTSITQESSFGSPTGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSNPFKSSKCSTAGSSPNSVSELSLASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTTQEGKIIELEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLNEFLELERHNNNMMAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKDLLELSCNELRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQKSDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVANDIKCEAQQELRTVKRKLLEEEEKNARLQKELGDVQGHGRVVTSRAAPPPVDEEPESSEVDAAGRWPGVCVSRTSPTPPESATTVKSLIKSFDLGRPGGAGQNISVHKTPRSPLSGIPVRTAPAAAVSPMQRHSTYSSVRPASRGVTQRLDLPDLPLSDILKGRTETLKPDPHLRKSPSLESLSRPPSLGFGDTRLLSASTRAWKPQSKLSVERKDPLAALAREYGGSKRNALLKWCQKKTQGYANIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELNSQEKKRNLLLAFEAAESVGIKPSLELSEMLYTDRPDWQSVMQYVAQIYKYFET NATD1 NATD1 NATD1_HUMAN (Q8N6N6-1) GO:0004402 (0.33) ! histone acetyltransferase activity GO:0006473 (0.68) ! protein acetylation; GO:0018393 (0.44) ! internal peptidyl-lysine acetylation; GO:0001702 (0.37) ! gastrulation with mouth forming second; GO:0016573 (0.35) ! histone acetylation; GO:0006474 (0.35) ! N-terminal protein amino acid acetylation; GO:0050794 (0.33) ! regulation of cellular process; GO:0048523 (0.27) ! negative regulation of cellular process; GO:0048518 (0.20) ! positive regulation of biological process; GO:0007162 (0.17) ! negative regulation of cell adhesion; GO:0050435 (0.14) ! beta-amyloid metabolic process; GO:0043066 (0.14) ! negative regulation of apoptotic process; GO:0018003 (0.14) ! peptidyl-lysine N6-acetylation; GO:0010628 (0.14) ! positive regulation of gene expression; GO:0006749 (0.10) ! glutathione metabolic process; GO:0051586 (0.06) ! positive regulation of dopamine uptake involved in synaptic transmission; GO:0042493 (0.05) ! response to drug; GO:0007507 (0.04) ! heart development; GO:0007368 (0.04) ! determination of left/right symmetry GO:0044424 (1.00) ! intracellular part; GO:0043227 (0.78) ! membrane-bounded organelle; GO:0043231 (0.70) ! intracellular membrane-bounded organelle; GO:0043234 (0.64) ! protein complex; GO:0031248 (0.55) ! protein acetyltransferase complex; GO:0044444 (0.53) ! cytoplasmic part; GO:0044446 (0.46) ! intracellular organelle part; GO:0005737 (0.36) ! cytoplasm; GO:0044428 (0.33) ! nuclear part; GO:0044427 (0.33) ! chromosomal part; GO:0044425 (0.30) ! membrane part; GO:0005634 (0.30) ! nucleus; GO:0005777 (0.28) ! peroxisome; GO:0016021 (0.26) ! integral component of membrane; GO:0044454 (0.22) ! nuclear chromosome part; GO:0031090 (0.22) ! organelle membrane; GO:0044421 (0.21) ! extracellular region part; GO:0005654 (0.20) ! nucleoplasm; GO:0000790 (0.20) ! nuclear chromatin; GO:0000781 (0.20) ! chromosome, telomeric region; GO:0000123 (0.20) ! histone acetyltransferase complex; GO:0070062 (0.16) ! extracellular exosome; GO:0005829 (0.15) ! cytosol; GO:0005789 (0.14) ! endoplasmic reticulum membrane; GO:0031966 (0.13) ! mitochondrial membrane; GO:0005794 (0.12) ! Golgi apparatus; GO:0033116 (0.10) ! endoplasmic reticulum-Golgi intermediate compartment membrane; GO:0005793 (0.10) ! endoplasmic reticulum-Golgi intermediate compartment; GO:0072487 (0.09) ! MSL complex; GO:0071339 (0.09) ! MLL1 complex; GO:0020015 (0.09) ! glycosome; GO:0016363 (0.09) ! nuclear matrix; GO:0005783 (0.09) ! endoplasmic reticulum; GO:0005694 (0.09) ! chromosome; GO:0000784 (0.09) ! nuclear chromosome, telomeric region; GO:0000776 (0.09) ! kinetochore; GO:0005739 (0.08) ! mitochondrion; GO:0005615 (0.06) ! extracellular space; GO:0005715 (0.03) ! late recombination nodule GO:0005515 ! protein binding 2 GO:0005515 ! protein binding 21238870-21253410 (17p11.2) MAHSAAAVPLGALEQGCPIRVEHDRRRRQFTVRLNGCHDRAVLLYEYVGKRIVDLQHTEVPDAYRGRGIAKHLAKAALDFVVEEDLKAHLTCWYIQKYVKENPLPQYLERLQP LYRM9 LYR motif-containing protein 9 LYRM9_HUMAN (A8MSI8-1) GO:0003824 (0.63) ! catalytic activity; GO:0008137 (0.52) ! NADH dehydrogenase (ubiquinone) activity; GO:0031071 (0.11) ! cysteine desulfurase activity; GO:0051536 (0.06) ! iron-sulfur cluster binding GO:0009987 (0.71) ! cellular process; GO:0044699 (0.50) ! single-organism process; GO:0044763 (0.42) ! single-organism cellular process; GO:0022607 (0.41) ! cellular component assembly; GO:0043623 (0.36) ! cellular protein complex assembly; GO:0008152 (0.33) ! metabolic process; GO:0070271 (0.32) ! protein complex biogenesis; GO:0033108 (0.32) ! mitochondrial respiratory chain complex assembly; GO:0050794 (0.31) ! regulation of cellular process; GO:0050896 (0.29) ! response to stimulus; GO:0044237 (0.28) ! cellular metabolic process; GO:0034553 (0.28) ! mitochondrial respiratory chain complex II assembly; GO:0016192 (0.28) ! vesicle-mediated transport; GO:0051716 (0.26) ! cellular response to stimulus; GO:0044710 (0.26) ! single-organism metabolic process; GO:0044700 (0.26) ! single organism signaling; GO:0007399 (0.26) ! nervous system development; GO:0007154 (0.26) ! cell communication; GO:0006120 (0.21) ! mitochondrial electron transport, NADH to ubiquinone; GO:0015976 (0.06) ! carbon utilization; GO:0006111 (0.06) ! regulation of gluconeogenesis; GO:0044281 (0.05) ! small molecule metabolic process; GO:0033615 (0.05) ! mitochondrial proton-transporting ATP synthase complex assembly; GO:0032981 (0.04) ! mitochondrial respiratory chain complex I assembly; GO:0019233 (0.04) ! sensory perception of pain; GO:0016226 (0.04) ! iron-sulfur cluster assembly; GO:0006979 (0.04) ! response to oxidative stress; GO:0044351 (0.03) ! macropinocytosis; GO:0034227 (0.02) ! tRNA thio-modification GO:0044424 (0.88) ! intracellular part; GO:0044444 (0.83) ! cytoplasmic part; GO:0043227 (0.82) ! membrane-bounded organelle; GO:0043231 (0.75) ! intracellular membrane-bounded organelle; GO:0044446 (0.65) ! intracellular organelle part; GO:0005737 (0.56) ! cytoplasm; GO:0005739 (0.53) ! mitochondrion; GO:0044421 (0.42) ! extracellular region part; GO:0070062 (0.40) ! extracellular exosome; GO:0016020 (0.40) ! membrane; GO:0005576 (0.40) ! extracellular region; GO:0031090 (0.26) ! organelle membrane; GO:0005829 (0.26) ! cytosol; GO:0098805 (0.25) ! whole membrane; GO:0098588 (0.25) ! bounding membrane of organelle; GO:0005856 (0.25) ! cytoskeleton; GO:0005815 (0.25) ! microtubule organizing center; GO:0044425 (0.22) ! membrane part; GO:0032991 (0.22) ! macromolecular complex; GO:0005634 (0.17) ! nucleus; GO:0044429 (0.16) ! mitochondrial part; GO:0044428 (0.16) ! nuclear part; GO:1990707 (0.13) ! nuclear subtelomeric heterochromatin; GO:0070971 (0.13) ! endoplasmic reticulum exit site; GO:0044732 (0.13) ! mitotic spindle pole body; GO:0043209 (0.13) ! myelin sheath; GO:0042470 (0.13) ! melanosome; GO:0031934 (0.13) ! mating-type region heterochromatin; GO:0031901 (0.13) ! early endosome membrane; GO:0031618 (0.13) ! nuclear pericentric heterochromatin; GO:0030958 (0.13) ! RITS complex; GO:0030669 (0.13) ! clathrin-coated endocytic vesicle membrane; GO:0005925 (0.13) ! focal adhesion; GO:0005886 (0.13) ! plasma membrane; GO:0005769 (0.13) ! early endosome; GO:0001772 (0.13) ! immunological synapse; GO:0000139 (0.13) ! Golgi membrane; GO:0044455 (0.11) ! mitochondrial membrane part; GO:0043234 (0.11) ! protein complex; GO:0005747 (0.09) ! mitochondrial respiratory chain complex I; GO:0070013 (0.07) ! intracellular organelle lumen; GO:0005759 (0.05) ! mitochondrial matrix; GO:0045171 (0.04) ! intercellular bridge; GO:0005654 (0.04) ! nucleoplasm; GO:1990221 (0.02) ! L-cysteine desulfurase complex; GO:0031314 (0.02) ! extrinsic component of mitochondrial inner membrane; GO:0005783 (0.02) ! endoplasmic reticulum; GO:0005758 (0.02) ! mitochondrial intermembrane space; GO:0005743 (0.01) ! mitochondrial inner membrane 2 27878314-27894752 (17q11.2) Brain - Nucleus accumbens (basal ganglia): 49.65; Brain - Anterior cingulate cortex (BA24): 47.32; Brain - Frontal Cortex (BA9): 43.70; Nerve - Tibial: 43.53; Brain - Cortex: 39.62; Brain - Amygdala: 35.88; Thyroid: 33.59; Adrenal Gland: 32.92; Pituitary: 31.76; Brain - Hippocampus: 31.04; Brain - Hypothalamus: 30.89; Ovary: 29.91; Brain - Caudate (basal ganglia): 29.16; Testis: 24.35; Brain - Putamen (basal ganglia): 24.18; Cervix - Endocervix: 22.66; Brain - Cerebellar Hemisphere: 22.33; Brain - Cerebellum: 21.83; Brain - Substantia nigra: 21.66; Uterus: 21.61; Fallopian Tube: 19.71; Brain - Spinal cord (cervical c-1): 19.26; Prostate: 18.25; Adipose - Subcutaneous: 17.05; Breast - Mammary Tissue: 16.66; Cervix - Ectocervix: 16.07; Spleen: 15.59; Artery - Tibial: 14.87; Kidney - Cortex: 14.54; Colon - Sigmoid: 14.42; Artery - Coronary: 13.84; Esophagus - Gastroesophageal Junction: 13.79; Artery - Aorta: 13.42; Skin - Sun Exposed (Lower leg): 13.34; Esophagus - Muscularis: 12.98; Skin - Not Sun Exposed (Suprapubic): 12.23; Bladder: 11.92; Vagina: 10.48; Minor Salivary Gland: 10.30; Lung: 10.10; Small Intestine - Terminal Ileum: 8.73; Adipose - Visceral (Omentum): 8.69; Stomach: 8.44; Pancreas: 8.09; Cells - Transformed fibroblasts: 8.01; Cells - EBV-transformed lymphocytes: 7.20; Muscle - Skeletal: 7.04; Colon - Transverse: 6.99; Heart - Atrial Appendage: 6.89; Liver: 5.42; Heart - Left Ventricle: 4.19; Esophagus - Mucosa: 3.77; Whole Blood: 3.06; MAPLPGAELVRRPLQLYRYLLRCCQQLPTKGIQQHYKHAVRQSFRVHSDEDNPERIQQIIKRAIEDADWIMNKYKKQN RAB34 Ras-related protein Rab-34, isoform NARR NARR_HUMAN (P0DI83-1) GO:0003824 (0.33) ! catalytic activity; GO:0003700 (0.25) ! transcription factor activity, sequence-specific DNA binding; GO:0000981 (0.23) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:1901363 (0.19) ! heterocyclic compound binding; GO:0097159 (0.19) ! organic cyclic compound binding; GO:0016740 (0.19) ! transferase activity; GO:0016787 (0.18) ! hydrolase activity; GO:0016772 (0.17) ! transferase activity, transferring phosphorus-containing groups; GO:0003676 (0.17) ! nucleic acid binding; GO:0003723 (0.14) ! RNA binding; GO:0005198 (0.12) ! structural molecule activity; GO:0044877 (0.10) ! macromolecular complex binding; GO:0016779 (0.10) ! nucleotidyltransferase activity; GO:0034062 (0.09) ! RNA polymerase activity; GO:0008092 (0.09) ! cytoskeletal protein binding; GO:0097367 (0.08) ! carbohydrate derivative binding; GO:0005215 (0.08) ! transporter activity; GO:0000166 (0.08) ! nucleotide binding; GO:0035639 (0.07) ! purine ribonucleoside triphosphate binding; GO:0032555 (0.07) ! purine ribonucleotide binding; GO:0032550 (0.07) ! purine ribonucleoside binding; GO:0032403 (0.07) ! protein complex binding; GO:0022857 (0.07) ! transmembrane transporter activity; GO:0004672 (0.07) ! protein kinase activity; GO:0003779 (0.07) ! actin binding; GO:0001104 (0.07) ! RNA polymerase II transcription cofactor activity; GO:0042802 (0.06) ! identical protein binding; GO:0017111 (0.06) ! nucleoside-triphosphatase activity; GO:0016491 (0.06) ! oxidoreductase activity; GO:0008324 (0.06) ! cation transmembrane transporter activity; GO:0008307 (0.06) ! structural constituent of muscle; GO:0005524 (0.06) ! ATP binding; GO:0004871 (0.06) ! signal transducer activity; GO:0004650 (0.06) ! polygalacturonase activity; GO:0003968 (0.06) ! RNA-directed RNA polymerase activity; GO:0097493 (0.05) ! structural molecule activity conferring elasticity; GO:0051371 (0.05) ! muscle alpha-actinin binding; GO:0051015 (0.05) ! actin filament binding; GO:0046873 (0.05) ! metal ion transmembrane transporter activity; GO:0019899 (0.05) ! enzyme binding; GO:0016887 (0.05) ! ATPase activity; GO:0016788 (0.05) ! hydrolase activity, acting on ester bonds; GO:0005261 (0.05) ! cation channel activity; GO:0004872 (0.05) ! receptor activity; GO:0004748 (0.05) ! ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; GO:0004674 (0.05) ! protein serine/threonine kinase activity; GO:0004459 (0.05) ! L-lactate dehydrogenase activity; GO:0098772 (0.04) ! molecular function regulator; GO:0005262 (0.04) ! calcium channel activity; GO:0005201 (0.04) ! extracellular matrix structural constituent; GO:0003777 (0.04) ! microtubule motor activity; GO:0003682 (0.04) ! chromatin binding; GO:0003677 (0.04) ! DNA binding; GO:0001055 (0.04) ! RNA polymerase II activity; GO:0030234 (0.03) ! enzyme regulator activity; GO:0022836 (0.03) ! gated channel activity; GO:0005543 (0.03) ! phospholipid binding; GO:0005509 (0.03) ! calcium ion binding; GO:0005102 (0.03) ! receptor binding; GO:0004702 (0.03) ! receptor signaling protein serine/threonine kinase activity; GO:0070011 (0.02) ! peptidase activity, acting on L-amino acid peptides; GO:0052689 (0.02) ! carboxylic ester hydrolase activity; GO:0044822 (0.02) ! poly(A) RNA binding; GO:0044212 (0.02) ! transcription regulatory region DNA binding; GO:0034596 (0.02) ! phosphatidylinositol phosphate 4-phosphatase activity; GO:0034595 (0.02) ! phosphatidylinositol phosphate 5-phosphatase activity; GO:0031491 (0.02) ! nucleosome binding; GO:0022804 (0.02) ! active transmembrane transporter activity; GO:0019901 (0.02) ! protein kinase binding; GO:0017016 (0.02) ! Ras GTPase binding; GO:0008331 (0.02) ! high voltage-gated calcium channel activity; GO:0008134 (0.02) ! transcription factor binding; GO:0008017 (0.02) ! microtubule binding; GO:0005516 (0.02) ! calmodulin binding; GO:0005096 (0.02) ! GTPase activator activity; GO:0004888 (0.02) ! transmembrane signaling receptor activity; GO:0071949 (0.01) ! FAD binding; GO:0071889 (0.01) ! 14-3-3 protein binding; GO:0050998 (0.01) ! nitric-oxide synthase binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0045505 (0.01) ! dynein intermediate chain binding; GO:0043812 (0.01) ! phosphatidylinositol-4-phosphate phosphatase activity; GO:0043621 (0.01) ! protein self-association; GO:0042800 (0.01) ! histone methyltransferase activity (H3-K4 specific); GO:0042626 (0.01) ! ATPase activity, coupled to transmembrane movement of substances; GO:0042043 (0.01) ! neurexin family protein binding; GO:0031433 (0.01) ! telethonin binding; GO:0030506 (0.01) ! ankyrin binding; GO:0022820 (0.01) ! potassium ion symporter activity; GO:0017154 (0.01) ! semaphorin receptor activity; GO:0017124 (0.01) ! SH3 domain binding; GO:0017049 (0.01) ! GTP-Rho binding; GO:0016709 (0.01) ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; GO:0016298 (0.01) ! lipase activity; GO:0015379 (0.01) ! potassium:chloride symporter activity; GO:0015279 (0.01) ! store-operated calcium channel activity; GO:0008237 (0.01) ! metallopeptidase activity; GO:0008201 (0.01) ! heparin binding; GO:0005546 (0.01) ! phosphatidylinositol-4,5-bisphosphate binding; GO:0005544 (0.01) ! calcium-dependent phospholipid binding; GO:0005522 (0.01) ! profilin binding; GO:0005487 (0.01) ! nucleocytoplasmic transporter activity; GO:0005200 (0.01) ! structural constituent of cytoskeleton; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0004930 (0.01) ! G-protein coupled receptor activity; GO:0004864 (0.01) ! protein phosphatase inhibitor activity; GO:0004842 (0.01) ! ubiquitin-protein transferase activity; GO:0004713 (0.01) ! protein tyrosine kinase activity; GO:0004525 (0.01) ! ribonuclease III activity; GO:0004439 (0.01) ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; GO:0004438 (0.01) ! phosphatidylinositol-3-phosphatase activity; GO:0004407 (0.01) ! histone deacetylase activity; GO:0004198 (0.01) ! calcium-dependent cysteine-type endopeptidase activity; GO:0004180 (0.01) ! carboxypeptidase activity; GO:0003924 (0.01) ! GTPase activity; GO:0003725 (0.01) ! double-stranded RNA binding; GO:0003713 (0.01) ! transcription coactivator activity; GO:0003690 (0.01) ! double-stranded DNA binding; GO:0002020 (0.01) ! protease binding; GO:0001664 (0.01) ! G-protein coupled receptor binding; GO:0001106 (0.01) ! RNA polymerase II transcription corepressor activity GO:0009987 (0.59) ! cellular process; GO:0065007 (0.56) ! biological regulation; GO:0032502 (0.51) ! developmental process; GO:0050794 (0.50) ! regulation of cellular process; GO:0044699 (0.49) ! single-organism process; GO:0044763 (0.41) ! single-organism cellular process; GO:0016043 (0.32) ! cellular component organization; GO:0080090 (0.31) ! regulation of primary metabolic process; GO:0060255 (0.31) ! regulation of macromolecule metabolic process; GO:0031323 (0.31) ! regulation of cellular metabolic process; GO:0031326 (0.30) ! regulation of cellular biosynthetic process; GO:2000112 (0.29) ! regulation of cellular macromolecule biosynthetic process; GO:0019219 (0.29) ! regulation of nucleobase-containing compound metabolic process; GO:0006355 (0.28) ! regulation of transcription, DNA-templated; GO:0008152 (0.27) ! metabolic process; GO:0006357 (0.27) ! regulation of transcription from RNA polymerase II promoter; GO:0044767 (0.25) ! single-organism developmental process; GO:0071704 (0.23) ! organic substance metabolic process; GO:0048856 (0.23) ! anatomical structure development; GO:0051179 (0.22) ! localization; GO:0044238 (0.21) ! primary metabolic process; GO:0044237 (0.21) ! cellular metabolic process; GO:0043170 (0.21) ! macromolecule metabolic process; GO:0051234 (0.20) ! establishment of localization; GO:0044260 (0.20) ! cellular macromolecule metabolic process; GO:0006810 (0.19) ! transport; GO:0022607 (0.18) ! cellular component assembly; GO:0051641 (0.16) ! cellular localization; GO:0032501 (0.16) ! multicellular organismal process; GO:0006996 (0.16) ! organelle organization; GO:0043933 (0.15) ! macromolecular complex subunit organization; GO:0009653 (0.15) ! anatomical structure morphogenesis; GO:0044710 (0.14) ! single-organism metabolic process; GO:0007010 (0.14) ! cytoskeleton organization; GO:0065003 (0.13) ! macromolecular complex assembly; GO:0051649 (0.13) ! establishment of localization in cell; GO:0050896 (0.13) ! response to stimulus; GO:0048869 (0.13) ! cellular developmental process; GO:0006807 (0.13) ! nitrogen compound metabolic process; GO:1902589 (0.12) ! single-organism organelle organization; GO:0090304 (0.12) ! nucleic acid metabolic process; GO:0034622 (0.12) ! cellular macromolecular complex assembly; GO:0007165 (0.12) ! signal transduction; GO:0048518 (0.11) ! positive regulation of biological process; GO:0046907 (0.11) ! intracellular transport; GO:0016070 (0.11) ! RNA metabolic process; GO:0065008 (0.10) ! regulation of biological quality; GO:0055114 (0.10) ! oxidation-reduction process; GO:0048522 (0.10) ! positive regulation of cellular process; GO:0044707 (0.10) ! single-multicellular organism process; GO:0044271 (0.10) ! cellular nitrogen compound biosynthetic process; GO:0030036 (0.10) ! actin cytoskeleton organization; GO:0009059 (0.10) ! macromolecule biosynthetic process; GO:0071822 (0.09) ! protein complex subunit organization; GO:0048731 (0.09) ! system development; GO:0032774 (0.09) ! RNA biosynthetic process; GO:0016310 (0.09) ! phosphorylation; GO:0048523 (0.08) ! negative regulation of cellular process; GO:0044267 (0.08) ! cellular protein metabolic process; GO:0034645 (0.08) ! cellular macromolecule biosynthetic process; GO:0031032 (0.08) ! actomyosin structure organization; GO:0006461 (0.08) ! protein complex assembly; GO:0003008 (0.08) ! system process; GO:0097659 (0.07) ! nucleic acid-templated transcription; GO:0051704 (0.07) ! multi-organism process; GO:0051128 (0.07) ! regulation of cellular component organization; GO:0048646 (0.07) ! anatomical structure formation involved in morphogenesis; GO:0048468 (0.07) ! cell development; GO:0045214 (0.07) ! sarcomere organization; GO:0016192 (0.07) ! vesicle-mediated transport; GO:0008104 (0.07) ! protein localization; GO:0007154 (0.07) ! cell communication; GO:0006928 (0.07) ! movement of cell or subcellular component; GO:1901575 (0.06) ! organic substance catabolic process; GO:1901564 (0.06) ! organonitrogen compound metabolic process; GO:0051239 (0.06) ! regulation of multicellular organismal process; GO:0051170 (0.06) ! nuclear import; GO:0050793 (0.06) ! regulation of developmental process; GO:0044723 (0.06) ! single-organism carbohydrate metabolic process; GO:0044712 (0.06) ! single-organism catabolic process; GO:0044281 (0.06) ! small molecule metabolic process; GO:0032989 (0.06) ! cellular component morphogenesis; GO:0030030 (0.06) ! cell projection organization; GO:0019637 (0.06) ! organophosphate metabolic process; GO:0019079 (0.06) ! viral genome replication; GO:0010927 (0.06) ! cellular component assembly involved in morphogenesis; GO:0009755 (0.06) ! hormone-mediated signaling pathway; GO:0007399 (0.06) ! nervous system development; GO:0007267 (0.06) ! cell-cell signaling; GO:0007017 (0.06) ! microtubule-based process; GO:0007015 (0.06) ! actin filament organization; GO:0006950 (0.06) ! response to stress; GO:0006464 (0.06) ! cellular protein modification process; GO:0006353 (0.06) ! DNA-templated transcription, termination; GO:0006259 (0.06) ! DNA metabolic process; GO:0001172 (0.06) ! transcription, RNA-templated; GO:0000387 (0.06) ! spliceosomal snRNP assembly; GO:0000245 (0.06) ! spliceosomal complex assembly; GO:2000026 (0.05) ! regulation of multicellular organismal development; GO:1903047 (0.05) ! mitotic cell cycle process; GO:1902578 (0.05) ! single-organism localization; GO:0070925 (0.05) ! organelle assembly; GO:0051716 (0.05) ! cellular response to stimulus; GO:0048858 (0.05) ! cell projection morphogenesis; GO:0048729 (0.05) ! tissue morphogenesis; GO:0045595 (0.05) ! regulation of cell differentiation; GO:0043623 (0.05) ! cellular protein complex assembly; GO:0032879 (0.05) ! regulation of localization; GO:0031325 (0.05) ! positive regulation of cellular metabolic process; GO:0030518 (0.05) ! intracellular steroid hormone receptor signaling pathway; GO:0023051 (0.05) ! regulation of signaling; GO:0022604 (0.05) ! regulation of cell morphogenesis; GO:0022414 (0.05) ! reproductive process; GO:0015949 (0.05) ! nucleobase-containing small molecule interconversion; GO:0010646 (0.05) ! regulation of cell communication; GO:0010604 (0.05) ! positive regulation of macromolecule metabolic process; GO:0009263 (0.05) ! deoxyribonucleotide biosynthetic process; GO:0007018 (0.05) ! microtubule-based movement; GO:0006936 (0.05) ! muscle contraction; GO:0006260 (0.05) ! DNA replication; GO:0006096 (0.05) ! glycolytic process; GO:1902680 (0.04) ! positive regulation of RNA biosynthetic process; GO:0090066 (0.04) ! regulation of anatomical structure size; GO:0055008 (0.04) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.04) ! cardiac myofibril assembly; GO:0048739 (0.04) ! cardiac muscle fiber development; GO:0044765 (0.04) ! single-organism transport; GO:0044702 (0.04) ! single organism reproductive process; GO:0042221 (0.04) ! response to chemical; GO:0040011 (0.04) ! locomotion; GO:0034613 (0.04) ! cellular protein localization; GO:0033043 (0.04) ! regulation of organelle organization; GO:0030241 (0.04) ! skeletal muscle myosin thick filament assembly; GO:0030240 (0.04) ! skeletal muscle thin filament assembly; GO:0010975 (0.04) ! regulation of neuron projection development; GO:0010769 (0.04) ! regulation of cell morphogenesis involved in differentiation; GO:0010628 (0.04) ! positive regulation of gene expression; GO:0009966 (0.04) ! regulation of signal transduction; GO:0009605 (0.04) ! response to external stimulus; GO:0007275 (0.04) ! multicellular organism development; GO:0006941 (0.04) ! striated muscle contraction; GO:0006897 (0.04) ! endocytosis; GO:0006468 (0.04) ! protein phosphorylation; GO:0006325 (0.04) ! chromatin organization; GO:0002376 (0.04) ! immune system process; GO:0070887 (0.03) ! cellular response to chemical stimulus; GO:0065009 (0.03) ! regulation of molecular function; GO:0061061 (0.03) ! muscle structure development; GO:0051606 (0.03) ! detection of stimulus; GO:0051130 (0.03) ! positive regulation of cellular component organization; GO:0051049 (0.03) ! regulation of transport; GO:0050808 (0.03) ! synapse organization; GO:0050770 (0.03) ! regulation of axonogenesis; GO:0048812 (0.03) ! neuron projection morphogenesis; GO:0048589 (0.03) ! developmental growth; GO:0048193 (0.03) ! Golgi vesicle transport; GO:0046331 (0.03) ! lateral inhibition; GO:0045944 (0.03) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045892 (0.03) ! negative regulation of transcription, DNA-templated; GO:0045087 (0.03) ! innate immune response; GO:0044719 (0.03) ! regulation of imaginal disc-derived wing size; GO:0043009 (0.03) ! chordate embryonic development; GO:0042391 (0.03) ! regulation of membrane potential; GO:0040005 (0.03) ! chitin-based cuticle attachment to epithelium; GO:0033554 (0.03) ! cellular response to stress; GO:0033365 (0.03) ! protein localization to organelle; GO:0030705 (0.03) ! cytoskeleton-dependent intracellular transport; GO:0015031 (0.03) ! protein transport; GO:0009967 (0.03) ! positive regulation of signal transduction; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0008362 (0.03) ! chitin-based embryonic cuticle biosynthetic process; GO:0007610 (0.03) ! behavior; GO:0007475 (0.03) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.03) ! open tracheal system development; GO:0007268 (0.03) ! chemical synaptic transmission; GO:0006812 (0.03) ! cation transport; GO:1902580 (0.02) ! single-organism cellular localization; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:1901990 (0.02) ! regulation of mitotic cell cycle phase transition; GO:0086010 (0.02) ! membrane depolarization during action potential; GO:0080134 (0.02) ! regulation of response to stress; GO:0061024 (0.02) ! membrane organization; GO:0060627 (0.02) ! regulation of vesicle-mediated transport; GO:0060271 (0.02) ! cilium morphogenesis; GO:0051315 (0.02) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051129 (0.02) ! negative regulation of cellular component organization; GO:0051050 (0.02) ! positive regulation of transport; GO:0050877 (0.02) ! neurological system process; GO:0050792 (0.02) ! regulation of viral process; GO:0050790 (0.02) ! regulation of catalytic activity; GO:0048813 (0.02) ! dendrite morphogenesis; GO:0048588 (0.02) ! developmental cell growth; GO:0046486 (0.02) ! glycerolipid metabolic process; GO:0044089 (0.02) ! positive regulation of cellular component biogenesis; GO:0043627 (0.02) ! response to estrogen; GO:0035556 (0.02) ! intracellular signal transduction; GO:0035372 (0.02) ! protein localization to microtubule; GO:0034501 (0.02) ! protein localization to kinetochore; GO:0031346 (0.02) ! positive regulation of cell projection organization; GO:0031134 (0.02) ! sister chromatid biorientation; GO:0030334 (0.02) ! regulation of cell migration; GO:0030155 (0.02) ! regulation of cell adhesion; GO:0030031 (0.02) ! cell projection assembly; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0022411 (0.02) ! cellular component disassembly; GO:0019725 (0.02) ! cellular homeostasis; GO:0016477 (0.02) ! cell migration; GO:0016337 (0.02) ! single organismal cell-cell adhesion; GO:0010638 (0.02) ! positive regulation of organelle organization; GO:0010035 (0.02) ! response to inorganic substance; GO:0009582 (0.02) ! detection of abiotic stimulus; GO:0009581 (0.02) ! detection of external stimulus; GO:0009416 (0.02) ! response to light stimulus; GO:0007626 (0.02) ! locomotory behavior; GO:0007527 (0.02) ! adult somatic muscle development; GO:0007519 (0.02) ! skeletal muscle tissue development; GO:0007416 (0.02) ! synapse assembly; GO:0007276 (0.02) ! gamete generation; GO:0007166 (0.02) ! cell surface receptor signaling pathway; GO:0006898 (0.02) ! receptor-mediated endocytosis; GO:0006887 (0.02) ! exocytosis; GO:0006886 (0.02) ! intracellular protein transport; GO:0006396 (0.02) ! RNA processing; GO:0006366 (0.02) ! transcription from RNA polymerase II promoter; GO:0006336 (0.02) ! DNA replication-independent nucleosome assembly; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0002009 (0.02) ! morphogenesis of an epithelium; GO:0001932 (0.02) ! regulation of protein phosphorylation; GO:0000226 (0.02) ! microtubule cytoskeleton organization; GO:0000041 (0.02) ! transition metal ion transport; GO:2000311 (0.01) ! regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; GO:1904837 (0.01) ! beta-catenin-TCF complex assembly; GO:1902582 (0.01) ! single-organism intracellular transport; GO:1902287 (0.01) ! semaphorin-plexin signaling pathway involved in axon guidance; GO:1902170 (0.01) ! cellular response to reactive nitrogen species; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:1900364 (0.01) ! negative regulation of mRNA polyadenylation; GO:1900246 (0.01) ! positive regulation of RIG-I signaling pathway; GO:1900245 (0.01) ! positive regulation of MDA-5 signaling pathway; GO:1900087 (0.01) ! positive regulation of G1/S transition of mitotic cell cycle; GO:0090502 (0.01) ! RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0090257 (0.01) ! regulation of muscle system process; GO:0071453 (0.01) ! cellular response to oxygen levels; GO:0071391 (0.01) ! cellular response to estrogen stimulus; GO:0071277 (0.01) ! cellular response to calcium ion; GO:0071214 (0.01) ! cellular response to abiotic stimulus; GO:0061000 (0.01) ! negative regulation of dendritic spine development; GO:0060287 (0.01) ! epithelial cilium movement involved in determination of left/right asymmetry; GO:0060048 (0.01) ! cardiac muscle contraction; GO:0060047 (0.01) ! heart contraction; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0060026 (0.01) ! convergent extension; GO:0051666 (0.01) ! actin cortical patch localization; GO:0051601 (0.01) ! exocyst localization; GO:0051568 (0.01) ! histone H3-K4 methylation; GO:0051491 (0.01) ! positive regulation of filopodium assembly; GO:0051480 (0.01) ! regulation of cytosolic calcium ion concentration; GO:0051345 (0.01) ! positive regulation of hydrolase activity; GO:0051276 (0.01) ! chromosome organization; GO:0051127 (0.01) ! positive regulation of actin nucleation; GO:0051056 (0.01) ! regulation of small GTPase mediated signal transduction; GO:0050906 (0.01) ! detection of stimulus involved in sensory perception; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0050772 (0.01) ! positive regulation of axonogenesis; GO:0050434 (0.01) ! positive regulation of viral transcription; GO:0048814 (0.01) ! regulation of dendrite morphogenesis; GO:0048769 (0.01) ! sarcomerogenesis; GO:0048738 (0.01) ! cardiac muscle tissue development; GO:0048675 (0.01) ! axon extension; GO:0048598 (0.01) ! embryonic morphogenesis; GO:0048513 (0.01) ! animal organ development; GO:0048489 (0.01) ! synaptic vesicle transport; GO:0048488 (0.01) ! synaptic vesicle endocytosis; GO:0048477 (0.01) ! oogenesis; GO:0046856 (0.01) ! phosphatidylinositol dephosphorylation; GO:0046847 (0.01) ! filopodium assembly; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046549 (0.01) ! retinal cone cell development; GO:0046330 (0.01) ! positive regulation of JNK cascade; GO:0046164 (0.01) ! alcohol catabolic process; GO:0045956 (0.01) ! positive regulation of calcium ion-dependent exocytosis; GO:0045859 (0.01) ! regulation of protein kinase activity; GO:0045055 (0.01) ! regulated exocytosis; GO:0045010 (0.01) ! actin nucleation; GO:0044802 (0.01) ! single-organism membrane organization; GO:0044351 (0.01) ! macropinocytosis; GO:0043581 (0.01) ! mycelium development; GO:0043123 (0.01) ! positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043087 (0.01) ! regulation of GTPase activity; GO:0042742 (0.01) ! defense response to bacterium; GO:0042110 (0.01) ! T cell activation; GO:0036269 (0.01) ! swimming behavior; GO:0035995 (0.01) ! detection of muscle stretch; GO:0035239 (0.01) ! tube morphogenesis; GO:0035082 (0.01) ! axoneme assembly; GO:0035047 (0.01) ! centrosomal and pronuclear rotation; GO:0035046 (0.01) ! pronuclear migration; GO:0034220 (0.01) ! ion transmembrane transport; GO:0033148 (0.01) ! positive regulation of intracellular estrogen receptor signaling pathway; GO:0032786 (0.01) ! positive regulation of DNA-templated transcription, elongation; GO:0032785 (0.01) ! negative regulation of DNA-templated transcription, elongation; GO:0031623 (0.01) ! receptor internalization; GO:0031532 (0.01) ! actin cytoskeleton reorganization; GO:0031505 (0.01) ! fungal-type cell wall organization; GO:0031054 (0.01) ! pre-miRNA processing; GO:0031053 (0.01) ! primary miRNA processing; GO:0030521 (0.01) ! androgen receptor signaling pathway; GO:0030516 (0.01) ! regulation of axon extension; GO:0030422 (0.01) ! production of siRNA involved in RNA interference; GO:0030048 (0.01) ! actin filament-based movement; GO:0030042 (0.01) ! actin filament depolymerization; GO:0023061 (0.01) ! signal release; GO:0022407 (0.01) ! regulation of cell-cell adhesion; GO:0021591 (0.01) ! ventricular system development; GO:0019932 (0.01) ! second-messenger-mediated signaling; GO:0019827 (0.01) ! stem cell population maintenance; GO:0019233 (0.01) ! sensory perception of pain; GO:0016567 (0.01) ! protein ubiquitination; GO:0016239 (0.01) ! positive regulation of macroautophagy; GO:0016080 (0.01) ! synaptic vesicle targeting; GO:0014866 (0.01) ! skeletal myofibril assembly; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0009968 (0.01) ! negative regulation of signal transduction; GO:0009584 (0.01) ! detection of visible light; GO:0008360 (0.01) ! regulation of cell shape; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0007612 (0.01) ! learning; GO:0007298 (0.01) ! border follicle cell migration; GO:0007283 (0.01) ! spermatogenesis; GO:0007274 (0.01) ! neuromuscular synaptic transmission; GO:0007186 (0.01) ! G-protein coupled receptor signaling pathway; GO:0007167 (0.01) ! enzyme linked receptor protein signaling pathway; GO:0007162 (0.01) ! negative regulation of cell adhesion; GO:0007158 (0.01) ! neuron cell-cell adhesion; GO:0007094 (0.01) ! mitotic spindle assembly checkpoint; GO:0007059 (0.01) ! chromosome segregation; GO:0006979 (0.01) ! response to oxidative stress; GO:0006900 (0.01) ! membrane budding; GO:0006893 (0.01) ! Golgi to plasma membrane transport; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006828 (0.01) ! manganese ion transport; GO:0006816 (0.01) ! calcium ion transport; GO:0006605 (0.01) ! protein targeting; GO:0006508 (0.01) ! proteolysis; GO:0006412 (0.01) ! translation; GO:0006370 (0.01) ! 7-methylguanosine mRNA capping; GO:0006368 (0.01) ! transcription elongation from RNA polymerase II promoter; GO:0006367 (0.01) ! transcription initiation from RNA polymerase II promoter; GO:0006342 (0.01) ! chromatin silencing; GO:0006310 (0.01) ! DNA recombination; GO:0006281 (0.01) ! DNA repair; GO:0006275 (0.01) ! regulation of DNA replication; GO:0003300 (0.01) ! cardiac muscle hypertrophy; GO:0002227 (0.01) ! innate immune response in mucosa; GO:0001966 (0.01) ! thigmotaxis; GO:0001952 (0.01) ! regulation of cell-matrix adhesion; GO:0001701 (0.01) ! in utero embryonic development; GO:0001555 (0.01) ! oocyte growth; GO:0000902 (0.01) ! cell morphogenesis; GO:0000398 (0.01) ! mRNA splicing, via spliceosome; GO:0000147 (0.01) ! actin cortical patch assembly; GO:0000132 (0.01) ! establishment of mitotic spindle orientation; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter GO:0044464 (0.88) ! cell part; GO:0044424 (0.73) ! intracellular part; GO:0044422 (0.50) ! organelle part; GO:0044446 (0.48) ! intracellular organelle part; GO:0032991 (0.46) ! macromolecular complex; GO:0016020 (0.46) ! membrane; GO:0044425 (0.44) ! membrane part; GO:0043234 (0.43) ! protein complex; GO:0043226 (0.42) ! organelle; GO:0043229 (0.41) ! intracellular organelle; GO:0043227 (0.38) ! membrane-bounded organelle; GO:0044444 (0.36) ! cytoplasmic part; GO:0031224 (0.36) ! intrinsic component of membrane; GO:0043231 (0.35) ! intracellular membrane-bounded organelle; GO:0016021 (0.31) ! integral component of membrane; GO:0005737 (0.28) ! cytoplasm; GO:0005886 (0.26) ! plasma membrane; GO:0044428 (0.25) ! nuclear part; GO:0005634 (0.24) ! nucleus; GO:0019012 (0.21) ! virion; GO:0043232 (0.18) ! intracellular non-membrane-bounded organelle; GO:0044451 (0.17) ! nucleoplasm part; GO:0020002 (0.16) ! host cell plasma membrane; GO:0044430 (0.15) ! cytoskeletal part; GO:0005829 (0.15) ! cytosol; GO:0005654 (0.15) ! nucleoplasm; GO:0005576 (0.12) ! extracellular region; GO:1902494 (0.11) ! catalytic complex; GO:0044459 (0.11) ! plasma membrane part; GO:0044449 (0.11) ! contractile fiber part; GO:0005739 (0.11) ! mitochondrion; GO:0097458 (0.10) ! neuron part; GO:0055036 (0.10) ! virion membrane; GO:0044429 (0.10) ! mitochondrial part; GO:0044421 (0.10) ! extracellular region part; GO:0031226 (0.10) ! intrinsic component of plasma membrane; GO:0019031 (0.10) ! viral envelope; GO:0005622 (0.10) ! intracellular; GO:0042995 (0.09) ! cell projection; GO:0030018 (0.09) ! Z disc; GO:0098796 (0.07) ! membrane protein complex; GO:0043005 (0.07) ! neuron projection; GO:0030529 (0.07) ! intracellular ribonucleoprotein complex; GO:0044445 (0.06) ! cytosolic part; GO:0031430 (0.06) ! M band; GO:0031090 (0.06) ! organelle membrane; GO:1990234 (0.05) ! transferase complex; GO:0097504 (0.05) ! Gemini of coiled bodies; GO:0070847 (0.05) ! core mediator complex; GO:0048476 (0.05) ! Holliday junction resolvase complex; GO:0045261 (0.05) ! proton-transporting ATP synthase complex, catalytic core F(1); GO:0044463 (0.05) ! cell projection part; GO:0044427 (0.05) ! chromosomal part; GO:0043204 (0.05) ! perikaryon; GO:0042597 (0.05) ! periplasmic space; GO:0036464 (0.05) ! cytoplasmic ribonucleoprotein granule; GO:0034719 (0.05) ! SMN-Sm protein complex; GO:0032797 (0.05) ! SMN complex; GO:0031988 (0.05) ! membrane-bounded vesicle; GO:0016592 (0.05) ! mediator complex; GO:0015030 (0.05) ! Cajal body; GO:0005971 (0.05) ! ribonucleoside-diphosphate reductase complex; GO:0005759 (0.05) ! mitochondrial matrix; GO:0005753 (0.05) ! mitochondrial proton-transporting ATP synthase complex; GO:0005743 (0.05) ! mitochondrial inner membrane; GO:0005730 (0.05) ! nucleolus; GO:0070062 (0.04) ! extracellular exosome; GO:0061695 (0.04) ! transferase complex, transferring phosphorus-containing groups; GO:0031012 (0.04) ! extracellular matrix; GO:0005887 (0.04) ! integral component of plasma membrane; GO:0005875 (0.04) ! microtubule associated complex; GO:0005865 (0.04) ! striated muscle thin filament; GO:0005859 (0.04) ! muscle myosin complex; GO:0045202 (0.03) ! synapse; GO:0044456 (0.03) ! synapse part; GO:0044448 (0.03) ! cell cortex part; GO:0030054 (0.03) ! cell junction; GO:0005871 (0.03) ! kinesin complex; GO:0005819 (0.03) ! spindle; GO:0005665 (0.03) ! DNA-directed RNA polymerase II, core complex; GO:0000776 (0.03) ! kinetochore; GO:0098590 (0.02) ! plasma membrane region; GO:0098589 (0.02) ! membrane region; GO:0030426 (0.02) ! growth cone; GO:0009986 (0.02) ! cell surface; GO:0005874 (0.02) ! microtubule; GO:0005856 (0.02) ! cytoskeleton; GO:0005813 (0.02) ! centrosome; GO:0005794 (0.02) ! Golgi apparatus; GO:0005694 (0.02) ! chromosome; GO:0005615 (0.02) ! extracellular space; GO:0000785 (0.02) ! chromatin; GO:0000777 (0.02) ! condensed chromosome kinetochore; GO:0098858 (0.01) ! actin-based cell projection; GO:0098797 (0.01) ! plasma membrane protein complex; GO:0098588 (0.01) ! bounding membrane of organelle; GO:0071013 (0.01) ! catalytic step 2 spliceosome; GO:0071006 (0.01) ! U2-type catalytic step 1 spliceosome; GO:0051286 (0.01) ! cell tip; GO:0051233 (0.01) ! spindle midzone; GO:0048788 (0.01) ! cytoskeleton of presynaptic active zone; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0045211 (0.01) ! postsynaptic membrane; GO:0045177 (0.01) ! apical part of cell; GO:0045121 (0.01) ! membrane raft; GO:0045111 (0.01) ! intermediate filament cytoskeleton; GO:0044666 (0.01) ! MLL3/4 complex; GO:0043197 (0.01) ! dendritic spine; GO:0043195 (0.01) ! terminal bouton; GO:0035371 (0.01) ! microtubule plus-end; GO:0034703 (0.01) ! cation channel complex; GO:0032155 (0.01) ! cell division site part; GO:0032153 (0.01) ! cell division site; GO:0032044 (0.01) ! DSIF complex; GO:0031674 (0.01) ! I band; GO:0031672 (0.01) ! A band; GO:0031253 (0.01) ! cell projection membrane; GO:0030496 (0.01) ! midbody; GO:0030479 (0.01) ! actin cortical patch; GO:0030424 (0.01) ! axon; GO:0030134 (0.01) ! ER to Golgi transport vesicle; GO:0030127 (0.01) ! COPII vesicle coat; GO:0022625 (0.01) ! cytosolic large ribosomal subunit; GO:0016235 (0.01) ! aggresome; GO:0014069 (0.01) ! postsynaptic density; GO:0012506 (0.01) ! vesicle membrane; GO:0009277 (0.01) ! fungal-type cell wall; GO:0005938 (0.01) ! cell cortex; GO:0005930 (0.01) ! axoneme; GO:0005929 (0.01) ! cilium; GO:0005924 (0.01) ! cell-substrate adherens junction; GO:0005918 (0.01) ! septate junction; GO:0005905 (0.01) ! clathrin-coated pit; GO:0005869 (0.01) ! dynactin complex; GO:0005802 (0.01) ! trans-Golgi network; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005768 (0.01) ! endosome; GO:0005643 (0.01) ! nuclear pore; GO:0002116 (0.01) ! semaphorin receptor complex; GO:0001917 (0.01) ! photoreceptor inner segment; GO:0000794 (0.01) ! condensed nuclear chromosome; GO:0000790 (0.01) ! nuclear chromatin; GO:0000235 (0.01) ! astral microtubule; GO:0000145 (0.01) ! exocyst GO:0005730 ! nucleolus; GO:0005634 ! nucleus 5 28714281-28718429 (17q11.2) High: stomach 2 (glandular cells);testis (Leydig cells);stomach 1 (glandular cells);parathyroid gland (glandular cells);small intestine (glandular cells);duodenum (glandular cells);prostate (glandular cells);pancreas (islets of Langerhans);Medium: colon (glandular cells; peripheral nerve/ganglion);gallbladder (glandular cells);kidney (cells in tubules);testis (cells in seminiferous ducts);thyroid gland (glandular cells);adrenal gland (glandular cells);endometrium 1 (glandular cells);endometrium 2 (glandular cells);smooth muscle (smooth muscle cells);cerebral cortex (neuronal cells; neuropil);placenta (decidual cells; trophoblastic cells);bronchus (respiratory epithelial cells);skeletal muscle (myocytes);urinary bladder (urothelial cells);liver (hepatocytes);rectum (glandular cells);cervix, uterine (glandular cells);cerebellum (cells in granular layer);soft tissue 1 (adipocytes; peripheral nerve);soft tissue 2 (adipocytes);nasopharynx (respiratory epithelial cells);lung (macrophages);heart muscle (myocytes);Low: seminal vesicle (glandular cells);colon (endothelial cells);esophagus (squamous epithelial cells);kidney (cells in glomeruli);caudate (glial cells; neuronal cells);tonsil (non-germinal center cells; squamous epithelial cells);epididymis (glandular cells);vagina (squamous epithelial cells);salivary gland (glandular cells);cerebral cortex (endothelial cells; glial cells);lymph node (non-germinal center cells);hippocampus (glial cells; neuronal cells);appendix (glandular cells; lymphoid tissue);breast (glandular cells; myoepithelial cells);cervix, uterine (squamous epithelial cells);pancreas (exocrine glandular cells);cerebellum (cells in molecular layer);fallopian tube (glandular cells);bone marrow (hematopoietic cells);soft tissue 2 (fibroblasts);soft tissue 1 (chondrocytes; fibroblasts);skin 1 (fibroblasts; keratinocytes; Langerhans; melanocytes);skin 2 (epidermal cells); Artery - Aorta: 196.70; Ovary: 190.40; Cervix - Endocervix: 177.00; Cervix - Ectocervix: 173.35; Uterus: 170.70; Cells - Transformed fibroblasts: 166.80; Fallopian Tube: 147.30; Artery - Tibial: 142.70; Artery - Coronary: 136.20; Nerve - Tibial: 130.30; Bladder: 117.40; Colon - Sigmoid: 117.20; Prostate: 117.05; Esophagus - Gastroesophageal Junction: 116.50; Thyroid: 107.70; Esophagus - Muscularis: 105.00; Vagina: 100.00; Adrenal Gland: 87.36; Lung: 77.58; Breast - Mammary Tissue: 71.19; Adipose - Subcutaneous: 69.75; Adipose - Visceral (Omentum): 61.37; Skin - Sun Exposed (Lower leg): 55.01; Skin - Not Sun Exposed (Suprapubic): 47.97; Kidney - Cortex: 47.63; Spleen: 47.18; Colon - Transverse: 44.55; Pituitary: 43.43; Heart - Atrial Appendage: 37.84; Minor Salivary Gland: 36.18; Esophagus - Mucosa: 35.27; Small Intestine - Terminal Ileum: 30.18; Brain - Nucleus accumbens (basal ganglia): 21.15; Stomach: 21.11; Testis: 19.46; Brain - Anterior cingulate cortex (BA24): 19.30; Brain - Substantia nigra: 18.07; Brain - Amygdala: 17.55; Brain - Cortex: 17.46; Brain - Caudate (basal ganglia): 16.67; Brain - Cerebellum: 16.17; Brain - Hypothalamus: 15.61; Brain - Frontal Cortex (BA9): 14.73; Brain - Putamen (basal ganglia): 13.82; Brain - Spinal cord (cervical c-1): 12.90; Brain - Hippocampus: 12.38; Cells - EBV-transformed lymphocytes: 11.47; Brain - Cerebellar Hemisphere: 10.55; Whole Blood: 10.32; Heart - Left Ventricle: 10.13; Muscle - Skeletal: 5.79; Pancreas: 4.07; Liver: 2.95; MVGQPQPRDDVGSPRPRVIVGTIRPRVIVGTIRPRVIVGSARARPPPDGTPRPQLAAEESPRPRVIFGTPRARVILGSPRPRVIVSSPWPAVVVASPRPRTPVGSPWPRVVVGTPRPRVIVGSPRARVADADPASAPSQGALQGRRQDEHSGTRAEGSRPGGAAPVPEEGGRFARAQRLPPPRHLRLPGAPDRHRGQI FAM222B FAM222B F222B_HUMAN (Q8WU58-1) GO:0003676 (0.52) ! nucleic acid binding; GO:0003824 (0.48) ! catalytic activity; GO:0043169 (0.32) ! cation binding; GO:0003712 (0.20) ! transcription cofactor activity; GO:0003723 (0.18) ! RNA binding; GO:0016787 (0.14) ! hydrolase activity; GO:0016740 (0.14) ! transferase activity; GO:0003713 (0.14) ! transcription coactivator activity; GO:0044822 (0.12) ! poly(A) RNA binding; GO:0003677 (0.10) ! DNA binding; GO:0016772 (0.09) ! transferase activity, transferring phosphorus-containing groups; GO:0008134 (0.07) ! transcription factor binding; GO:0003700 (0.07) ! transcription factor activity, sequence-specific DNA binding; GO:0001104 (0.07) ! RNA polymerase II transcription cofactor activity; GO:0044877 (0.06) ! macromolecular complex binding; GO:0019899 (0.06) ! enzyme binding; GO:0005102 (0.06) ! receptor binding; GO:0001191 (0.06) ! transcriptional repressor activity, RNA polymerase II transcription factor binding; GO:0044212 (0.05) ! transcription regulatory region DNA binding; GO:0016788 (0.05) ! hydrolase activity, acting on ester bonds; GO:0005261 (0.05) ! cation channel activity; GO:0004672 (0.05) ! protein kinase activity; GO:0003714 (0.05) ! transcription corepressor activity; GO:0003682 (0.05) ! chromatin binding; GO:0051427 (0.04) ! hormone receptor binding; GO:0046873 (0.04) ! metal ion transmembrane transporter activity; GO:0043565 (0.04) ! sequence-specific DNA binding; GO:0030374 (0.04) ! ligand-dependent nuclear receptor transcription coactivator activity; GO:0022843 (0.04) ! voltage-gated cation channel activity; GO:0016887 (0.04) ! ATPase activity; GO:0016779 (0.04) ! nucleotidyltransferase activity; GO:0008233 (0.04) ! peptidase activity; GO:0005198 (0.04) ! structural molecule activity; GO:0004674 (0.04) ! protein serine/threonine kinase activity; GO:0004407 (0.04) ! histone deacetylase activity; GO:0001105 (0.04) ! RNA polymerase II transcription coactivator activity; GO:0070491 (0.03) ! repressing transcription factor binding; GO:0042623 (0.03) ! ATPase activity, coupled; GO:0005245 (0.03) ! voltage-gated calcium channel activity; GO:0004540 (0.03) ! ribonuclease activity; GO:0003964 (0.03) ! RNA-directed DNA polymerase activity; GO:0003887 (0.03) ! DNA-directed DNA polymerase activity; GO:0000976 (0.03) ! transcription regulatory region sequence-specific DNA binding; GO:0098772 (0.02) ! molecular function regulator; GO:0032403 (0.02) ! protein complex binding; GO:0017016 (0.02) ! Ras GTPase binding; GO:0008331 (0.02) ! high voltage-gated calcium channel activity; GO:0008190 (0.02) ! eukaryotic initiation factor 4E binding; GO:0008094 (0.02) ! DNA-dependent ATPase activity; GO:0008092 (0.02) ! cytoskeletal protein binding; GO:0008022 (0.02) ! protein C-terminus binding; GO:0005543 (0.02) ! phospholipid binding; GO:0005201 (0.02) ! extracellular matrix structural constituent; GO:0004402 (0.02) ! histone acetyltransferase activity; GO:0001106 (0.02) ! RNA polymerase II transcription corepressor activity; GO:0000987 (0.02) ! core promoter proximal region sequence-specific DNA binding; GO:0000981 (0.02) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0000977 (0.02) ! RNA polymerase II regulatory region sequence-specific DNA binding; GO:0070577 (0.01) ! lysine-acetylated histone binding; GO:0050681 (0.01) ! androgen receptor binding; GO:0046966 (0.01) ! thyroid hormone receptor binding; GO:0043426 (0.01) ! MRF binding; GO:0042800 (0.01) ! histone methyltransferase activity (H3-K4 specific); GO:0042277 (0.01) ! peptide binding; GO:0036002 (0.01) ! pre-mRNA binding; GO:0034596 (0.01) ! phosphatidylinositol phosphate 4-phosphatase activity; GO:0034595 (0.01) ! phosphatidylinositol phosphate 5-phosphatase activity; GO:0033613 (0.01) ! activating transcription factor binding; GO:0031491 (0.01) ! nucleosome binding; GO:0031490 (0.01) ! chromatin DNA binding; GO:0019904 (0.01) ! protein domain specific binding; GO:0019901 (0.01) ! protein kinase binding; GO:0017137 (0.01) ! Rab GTPase binding; GO:0016922 (0.01) ! ligand-dependent nuclear receptor binding; GO:0008536 (0.01) ! Ran GTPase binding; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008017 (0.01) ! microtubule binding; GO:0008013 (0.01) ! beta-catenin binding; GO:0005546 (0.01) ! phosphatidylinositol-4,5-bisphosphate binding; GO:0005544 (0.01) ! calcium-dependent phospholipid binding; GO:0005522 (0.01) ! profilin binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005249 (0.01) ! voltage-gated potassium channel activity; GO:0005096 (0.01) ! GTPase activator activity; GO:0004872 (0.01) ! receptor activity; GO:0004842 (0.01) ! ubiquitin-protein transferase activity; GO:0004725 (0.01) ! protein tyrosine phosphatase activity; GO:0004702 (0.01) ! receptor signaling protein serine/threonine kinase activity; GO:0004620 (0.01) ! phospholipase activity; GO:0004252 (0.01) ! serine-type endopeptidase activity; GO:0004004 (0.01) ! ATP-dependent RNA helicase activity; GO:0003779 (0.01) ! actin binding; GO:0003777 (0.01) ! microtubule motor activity; GO:0003729 (0.01) ! mRNA binding; GO:0003684 (0.01) ! damaged DNA binding; GO:0002039 (0.01) ! p53 binding; GO:0001228 (0.01) ! transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding; GO:0001158 (0.01) ! enhancer sequence-specific DNA binding; GO:0001099 (0.01) ! basal RNA polymerase II transcription machinery binding; GO:0001085 (0.01) ! RNA polymerase II transcription factor binding; GO:0001055 (0.01) ! RNA polymerase II activity; GO:0001047 (0.01) ! core promoter binding; GO:0000982 (0.01) ! transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0000978 (0.01) ! RNA polymerase II core promoter proximal region sequence-specific DNA binding; GO:0000384 (0.01) ! first spliceosomal transesterification activity GO:0009987 (0.61) ! cellular process; GO:0065007 (0.55) ! biological regulation; GO:0050789 (0.52) ! regulation of biological process; GO:0050794 (0.49) ! regulation of cellular process; GO:0044699 (0.41) ! single-organism process; GO:0019222 (0.33) ! regulation of metabolic process; GO:0060255 (0.32) ! regulation of macromolecule metabolic process; GO:0031323 (0.32) ! regulation of cellular metabolic process; GO:0044763 (0.31) ! single-organism cellular process; GO:0080090 (0.30) ! regulation of primary metabolic process; GO:0071704 (0.30) ! organic substance metabolic process; GO:0044238 (0.30) ! primary metabolic process; GO:0044237 (0.30) ! cellular metabolic process; GO:0010468 (0.30) ! regulation of gene expression; GO:0051171 (0.29) ! regulation of nitrogen compound metabolic process; GO:0044260 (0.29) ! cellular macromolecule metabolic process; GO:0016043 (0.29) ! cellular component organization; GO:0009889 (0.29) ! regulation of biosynthetic process; GO:2000112 (0.28) ! regulation of cellular macromolecule biosynthetic process; GO:0048518 (0.28) ! positive regulation of biological process; GO:0019219 (0.28) ! regulation of nucleobase-containing compound metabolic process; GO:0006355 (0.27) ! regulation of transcription, DNA-templated; GO:0032502 (0.26) ! developmental process; GO:0044767 (0.25) ! single-organism developmental process; GO:0048522 (0.23) ! positive regulation of cellular process; GO:0048519 (0.22) ! negative regulation of biological process; GO:0032501 (0.21) ! multicellular organismal process; GO:0050896 (0.19) ! response to stimulus; GO:0044707 (0.19) ! single-multicellular organism process; GO:0043933 (0.19) ! macromolecular complex subunit organization; GO:1902680 (0.18) ! positive regulation of RNA biosynthetic process; GO:0048856 (0.18) ! anatomical structure development; GO:0016070 (0.18) ! RNA metabolic process; GO:0010628 (0.18) ! positive regulation of gene expression; GO:0009892 (0.18) ! negative regulation of metabolic process; GO:0006357 (0.18) ! regulation of transcription from RNA polymerase II promoter; GO:0048523 (0.17) ! negative regulation of cellular process; GO:0010605 (0.17) ! negative regulation of macromolecule metabolic process; GO:0010629 (0.16) ! negative regulation of gene expression; GO:0051128 (0.15) ! regulation of cellular component organization; GO:0007165 (0.15) ! signal transduction; GO:0045893 (0.14) ! positive regulation of transcription, DNA-templated; GO:0006996 (0.14) ! organelle organization; GO:0031324 (0.13) ! negative regulation of cellular metabolic process; GO:0019538 (0.13) ! protein metabolic process; GO:0016071 (0.13) ! mRNA metabolic process; GO:0006950 (0.13) ! response to stress; GO:0065008 (0.12) ! regulation of biological quality; GO:0051179 (0.12) ! localization; GO:0048869 (0.12) ! cellular developmental process; GO:0022607 (0.12) ! cellular component assembly; GO:0009653 (0.12) ! anatomical structure morphogenesis; GO:0051172 (0.11) ! negative regulation of nitrogen compound metabolic process; GO:0048583 (0.11) ! regulation of response to stimulus; GO:0045944 (0.11) ! positive regulation of transcription from RNA polymerase II promoter; GO:0033043 (0.11) ! regulation of organelle organization; GO:0006810 (0.11) ! transport; GO:0006464 (0.11) ! cellular protein modification process; GO:0065003 (0.10) ! macromolecular complex assembly; GO:0051716 (0.10) ! cellular response to stimulus; GO:0045892 (0.10) ! negative regulation of transcription, DNA-templated; GO:0044271 (0.10) ! cellular nitrogen compound biosynthetic process; GO:0023051 (0.10) ! regulation of signaling; GO:0010646 (0.10) ! regulation of cell communication; GO:0009059 (0.10) ! macromolecule biosynthetic process; GO:0006396 (0.10) ! RNA processing; GO:0006325 (0.10) ! chromatin organization; GO:0048513 (0.09) ! animal organ development; GO:0034622 (0.09) ! cellular macromolecular complex assembly; GO:0032774 (0.09) ! RNA biosynthetic process; GO:0009966 (0.09) ! regulation of signal transduction; GO:0007166 (0.09) ! cell surface receptor signaling pathway; GO:0000398 (0.09) ! mRNA splicing, via spliceosome; GO:0070925 (0.08) ! organelle assembly; GO:0044087 (0.08) ! regulation of cellular component biogenesis; GO:0034645 (0.08) ! cellular macromolecule biosynthetic process; GO:0033554 (0.08) ! cellular response to stress; GO:0032879 (0.08) ! regulation of localization; GO:0030154 (0.08) ! cell differentiation; GO:0022618 (0.08) ! ribonucleoprotein complex assembly; GO:1902115 (0.07) ! regulation of organelle assembly; GO:0065009 (0.07) ! regulation of molecular function; GO:0051704 (0.07) ! multi-organism process; GO:0051641 (0.07) ! cellular localization; GO:0051239 (0.07) ! regulation of multicellular organismal process; GO:0051049 (0.07) ! regulation of transport; GO:0019827 (0.07) ! stem cell population maintenance; GO:0006974 (0.07) ! cellular response to DNA damage stimulus; GO:0006351 (0.07) ! transcription, DNA-templated; GO:0006259 (0.07) ! DNA metabolic process; GO:0098781 (0.06) ! ncRNA transcription; GO:0051649 (0.06) ! establishment of localization in cell; GO:0051052 (0.06) ! regulation of DNA metabolic process; GO:0050793 (0.06) ! regulation of developmental process; GO:0050434 (0.06) ! positive regulation of viral transcription; GO:0044702 (0.06) ! single organism reproductive process; GO:0042221 (0.06) ! response to chemical; GO:0035019 (0.06) ! somatic stem cell population maintenance; GO:0034063 (0.06) ! stress granule assembly; GO:0031047 (0.06) ! gene silencing by RNA; GO:0010603 (0.06) ! regulation of cytoplasmic mRNA processing body assembly; GO:0007610 (0.06) ! behavior; GO:0006367 (0.06) ! transcription initiation from RNA polymerase II promoter; GO:0006366 (0.06) ! transcription from RNA polymerase II promoter; GO:0006281 (0.06) ! DNA repair; GO:0003002 (0.06) ! regionalization; GO:0002376 (0.06) ! immune system process; GO:0000122 (0.06) ! negative regulation of transcription from RNA polymerase II promoter; GO:2000026 (0.05) ! regulation of multicellular organismal development; GO:1902578 (0.05) ! single-organism localization; GO:0046907 (0.05) ! intracellular transport; GO:0044093 (0.05) ! positive regulation of molecular function; GO:0042795 (0.05) ! snRNA transcription from RNA polymerase II promoter; GO:0035107 (0.05) ! appendage morphogenesis; GO:0033120 (0.05) ! positive regulation of RNA splicing; GO:0031399 (0.05) ! regulation of protein modification process; GO:0016570 (0.05) ! histone modification; GO:0010033 (0.05) ! response to organic substance; GO:0009968 (0.05) ! negative regulation of signal transduction; GO:0009888 (0.05) ! tissue development; GO:0009886 (0.05) ! post-embryonic morphogenesis; GO:0008543 (0.05) ! fibroblast growth factor receptor signaling pathway; GO:0006370 (0.05) ! 7-methylguanosine mRNA capping; GO:0006368 (0.05) ! transcription elongation from RNA polymerase II promoter; GO:0006353 (0.05) ! DNA-templated transcription, termination; GO:0006298 (0.05) ! mismatch repair; GO:0006283 (0.05) ! transcription-coupled nucleotide-excision repair; GO:0003008 (0.05) ! system process; GO:0001172 (0.05) ! transcription, RNA-templated; GO:0000018 (0.05) ! regulation of DNA recombination; GO:1902275 (0.04) ! regulation of chromatin organization; GO:0051240 (0.04) ! positive regulation of multicellular organismal process; GO:0051094 (0.04) ! positive regulation of developmental process; GO:0051050 (0.04) ! positive regulation of transport; GO:0050877 (0.04) ! neurological system process; GO:0048731 (0.04) ! system development; GO:0048646 (0.04) ! anatomical structure formation involved in morphogenesis; GO:0048584 (0.04) ! positive regulation of response to stimulus; GO:0048468 (0.04) ! cell development; GO:0045595 (0.04) ! regulation of cell differentiation; GO:0044765 (0.04) ! single-organism transport; GO:0035556 (0.04) ! intracellular signal transduction; GO:0035282 (0.04) ! segmentation; GO:0032844 (0.04) ! regulation of homeostatic process; GO:0018205 (0.04) ! peptidyl-lysine modification; GO:0016192 (0.04) ! vesicle-mediated transport; GO:0009605 (0.04) ! response to external stimulus; GO:0008104 (0.04) ! protein localization; GO:0007010 (0.04) ! cytoskeleton organization; GO:0006955 (0.04) ! immune response; GO:0006952 (0.04) ! defense response; GO:0006468 (0.04) ! protein phosphorylation; GO:0006338 (0.04) ! chromatin remodeling; GO:0003006 (0.04) ! developmental process involved in reproduction; GO:2000021 (0.03) ! regulation of ion homeostasis; GO:1902589 (0.03) ! single-organism organelle organization; GO:1902531 (0.03) ! regulation of intracellular signal transduction; GO:0090066 (0.03) ! regulation of anatomical structure size; GO:0086010 (0.03) ! membrane depolarization during action potential; GO:0071822 (0.03) ! protein complex subunit organization; GO:0071702 (0.03) ! organic substance transport; GO:0061061 (0.03) ! muscle structure development; GO:0051960 (0.03) ! regulation of nervous system development; GO:0051707 (0.03) ! response to other organism; GO:0051130 (0.03) ! positive regulation of cellular component organization; GO:0050890 (0.03) ! cognition; GO:0050790 (0.03) ! regulation of catalytic activity; GO:0048598 (0.03) ! embryonic morphogenesis; GO:0048589 (0.03) ! developmental growth; GO:0048569 (0.03) ! post-embryonic organ development; GO:0045879 (0.03) ! negative regulation of smoothened signaling pathway; GO:0045087 (0.03) ! innate immune response; GO:0044708 (0.03) ! single-organism behavior; GO:0042059 (0.03) ! negative regulation of epidermal growth factor receptor signaling pathway; GO:0040011 (0.03) ! locomotion; GO:0040008 (0.03) ! regulation of growth; GO:0035065 (0.03) ! regulation of histone acetylation; GO:0034613 (0.03) ! cellular protein localization; GO:0032989 (0.03) ! cellular component morphogenesis; GO:0032414 (0.03) ! positive regulation of ion transmembrane transporter activity; GO:0030030 (0.03) ! cell projection organization; GO:0022412 (0.03) ! cellular process involved in reproduction in multicellular organism; GO:0022402 (0.03) ! cell cycle process; GO:0019220 (0.03) ! regulation of phosphate metabolic process; GO:0009967 (0.03) ! positive regulation of signal transduction; GO:0009887 (0.03) ! organ morphogenesis; GO:0009880 (0.03) ! embryonic pattern specification; GO:0009790 (0.03) ! embryo development; GO:0009725 (0.03) ! response to hormone; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0008586 (0.03) ! imaginal disc-derived wing vein morphogenesis; GO:0007480 (0.03) ! imaginal disc-derived leg morphogenesis; GO:0007379 (0.03) ! segment specification; GO:0007267 (0.03) ! cell-cell signaling; GO:0007221 (0.03) ! positive regulation of transcription of Notch receptor target; GO:0007017 (0.03) ! microtubule-based process; GO:0006928 (0.03) ! movement of cell or subcellular component; GO:0006379 (0.03) ! mRNA cleavage; GO:0002682 (0.03) ! regulation of immune system process; GO:0001654 (0.03) ! eye development; GO:1903530 (0.02) ! regulation of secretion by cell; GO:1903047 (0.02) ! mitotic cell cycle process; GO:1902582 (0.02) ! single-organism intracellular transport; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:0090287 (0.02) ! regulation of cellular response to growth factor stimulus; GO:0070887 (0.02) ! cellular response to chemical stimulus; GO:0060627 (0.02) ! regulation of vesicle-mediated transport; GO:0050776 (0.02) ! regulation of immune response; GO:0050767 (0.02) ! regulation of neurogenesis; GO:0048812 (0.02) ! neuron projection morphogenesis; GO:0048729 (0.02) ! tissue morphogenesis; GO:0048639 (0.02) ! positive regulation of developmental growth; GO:0048193 (0.02) ! Golgi vesicle transport; GO:0046331 (0.02) ! lateral inhibition; GO:0045936 (0.02) ! negative regulation of phosphate metabolic process; GO:0045597 (0.02) ! positive regulation of cell differentiation; GO:0044719 (0.02) ! regulation of imaginal disc-derived wing size; GO:0044265 (0.02) ! cellular macromolecule catabolic process; GO:0043086 (0.02) ! negative regulation of catalytic activity; GO:0043009 (0.02) ! chordate embryonic development; GO:0042742 (0.02) ! defense response to bacterium; GO:0042325 (0.02) ! regulation of phosphorylation; GO:0042127 (0.02) ! regulation of cell proliferation; GO:0040029 (0.02) ! regulation of gene expression, epigenetic; GO:0040005 (0.02) ! chitin-based cuticle attachment to epithelium; GO:0034728 (0.02) ! nucleosome organization; GO:0034504 (0.02) ! protein localization to nucleus; GO:0032940 (0.02) ! secretion by cell; GO:0032446 (0.02) ! protein modification by small protein conjugation; GO:0032197 (0.02) ! transposition, RNA-mediated; GO:0031347 (0.02) ! regulation of defense response; GO:0030518 (0.02) ! intracellular steroid hormone receptor signaling pathway; GO:0030182 (0.02) ! neuron differentiation; GO:0022411 (0.02) ! cellular component disassembly; GO:0016575 (0.02) ! histone deacetylation; GO:0016573 (0.02) ! histone acetylation; GO:0016477 (0.02) ! cell migration; GO:0010959 (0.02) ! regulation of metal ion transport; GO:0010941 (0.02) ! regulation of cell death; GO:0010638 (0.02) ! positive regulation of organelle organization; GO:0010564 (0.02) ! regulation of cell cycle process; GO:0009952 (0.02) ! anterior/posterior pattern specification; GO:0008362 (0.02) ! chitin-based embryonic cuticle biosynthetic process; GO:0007626 (0.02) ! locomotory behavior; GO:0007614 (0.02) ! short-term memory; GO:0007600 (0.02) ! sensory perception; GO:0007526 (0.02) ! larval somatic muscle development; GO:0007507 (0.02) ! heart development; GO:0007475 (0.02) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.02) ! open tracheal system development; GO:0007420 (0.02) ! brain development; GO:0007346 (0.02) ! regulation of mitotic cell cycle; GO:0007219 (0.02) ! Notch signaling pathway; GO:0006913 (0.02) ! nucleocytoplasmic transport; GO:0006897 (0.02) ! endocytosis; GO:0006886 (0.02) ! intracellular protein transport; GO:0006812 (0.02) ! cation transport; GO:0006461 (0.02) ! protein complex assembly; GO:0002684 (0.02) ! positive regulation of immune system process; GO:0002244 (0.02) ! hematopoietic progenitor cell differentiation; GO:0002121 (0.02) ! inter-male aggressive behavior; GO:0001568 (0.02) ! blood vessel development; GO:0000226 (0.02) ! microtubule cytoskeleton organization; GO:2000651 (0.01) ! positive regulation of sodium ion transmembrane transporter activity; GO:2000241 (0.01) ! regulation of reproductive process; GO:1904837 (0.01) ! beta-catenin-TCF complex assembly; GO:1903532 (0.01) ! positive regulation of secretion by cell; GO:1903305 (0.01) ! regulation of regulated secretory pathway; GO:1902685 (0.01) ! positive regulation of receptor localization to synapse; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1902107 (0.01) ! positive regulation of leukocyte differentiation; GO:1901991 (0.01) ! negative regulation of mitotic cell cycle phase transition; GO:1901522 (0.01) ! positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus; GO:1900087 (0.01) ! positive regulation of G1/S transition of mitotic cell cycle; GO:0099643 (0.01) ! signal release from synapse; GO:0099531 (0.01) ! presynaptic process involved in chemical synaptic transmission; GO:0097305 (0.01) ! response to alcohol; GO:0097150 (0.01) ! neuronal stem cell population maintenance; GO:0090596 (0.01) ! sensory organ morphogenesis; GO:0090526 (0.01) ! regulation of gluconeogenesis involved in cellular glucose homeostasis; GO:0090276 (0.01) ! regulation of peptide hormone secretion; GO:0090114 (0.01) ! COPII-coated vesicle budding; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0072331 (0.01) ! signal transduction by p53 class mediator; GO:0071363 (0.01) ! cellular response to growth factor stimulus; GO:0071300 (0.01) ! cellular response to retinoic acid; GO:0070588 (0.01) ! calcium ion transmembrane transport; GO:0070050 (0.01) ! neuron cellular homeostasis; GO:0061418 (0.01) ! regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:0061314 (0.01) ! Notch signaling involved in heart development; GO:0060765 (0.01) ! regulation of androgen receptor signaling pathway; GO:0060674 (0.01) ! placenta blood vessel development; GO:0060560 (0.01) ! developmental growth involved in morphogenesis; GO:0060536 (0.01) ! cartilage morphogenesis; GO:0060485 (0.01) ! mesenchyme development; GO:0060429 (0.01) ! epithelium development; GO:0060411 (0.01) ! cardiac septum morphogenesis; GO:0060341 (0.01) ! regulation of cellular localization; GO:0060271 (0.01) ! cilium morphogenesis; GO:0060070 (0.01) ! canonical Wnt signaling pathway; GO:0060047 (0.01) ! heart contraction; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0055006 (0.01) ! cardiac cell development; GO:0055001 (0.01) ! muscle cell development; GO:0051924 (0.01) ! regulation of calcium ion transport; GO:0051656 (0.01) ! establishment of organelle localization; GO:0051568 (0.01) ! histone H3-K4 methylation; GO:0051495 (0.01) ! positive regulation of cytoskeleton organization; GO:0051301 (0.01) ! cell division; GO:0051276 (0.01) ! chromosome organization; GO:0051216 (0.01) ! cartilage development; GO:0051129 (0.01) ! negative regulation of cellular component organization; GO:0051091 (0.01) ! positive regulation of sequence-specific DNA binding transcription factor activity; GO:0051051 (0.01) ! negative regulation of transport; GO:0050829 (0.01) ! defense response to Gram-negative bacterium; GO:0050808 (0.01) ! synapse organization; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0050769 (0.01) ! positive regulation of neurogenesis; GO:0050768 (0.01) ! negative regulation of neurogenesis; GO:0048936 (0.01) ! peripheral nervous system neuron axonogenesis; GO:0048844 (0.01) ! artery morphogenesis; GO:0048806 (0.01) ! genitalia development; GO:0048703 (0.01) ! embryonic viscerocranium morphogenesis; GO:0048701 (0.01) ! embryonic cranial skeleton morphogenesis; GO:0048666 (0.01) ! neuron development; GO:0048580 (0.01) ! regulation of post-embryonic development; GO:0048488 (0.01) ! synaptic vesicle endocytosis; GO:0048259 (0.01) ! regulation of receptor-mediated endocytosis; GO:0046622 (0.01) ! positive regulation of organ growth; GO:0046578 (0.01) ! regulation of Ras protein signal transduction; GO:0046488 (0.01) ! phosphatidylinositol metabolic process; GO:0045815 (0.01) ! positive regulation of gene expression, epigenetic; GO:0045747 (0.01) ! positive regulation of Notch signaling pathway; GO:0045664 (0.01) ! regulation of neuron differentiation; GO:0045089 (0.01) ! positive regulation of innate immune response; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0044089 (0.01) ! positive regulation of cellular component biogenesis; GO:0044057 (0.01) ! regulation of system process; GO:0043967 (0.01) ! histone H4 acetylation; GO:0043966 (0.01) ! histone H3 acetylation; GO:0043923 (0.01) ! positive regulation by host of viral transcription; GO:0043623 (0.01) ! cellular protein complex assembly; GO:0043123 (0.01) ! positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043085 (0.01) ! positive regulation of catalytic activity; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0043044 (0.01) ! ATP-dependent chromatin remodeling; GO:0042921 (0.01) ! glucocorticoid receptor signaling pathway; GO:0042692 (0.01) ! muscle cell differentiation; GO:0042594 (0.01) ! response to starvation; GO:0042472 (0.01) ! inner ear morphogenesis; GO:0042147 (0.01) ! retrograde transport, endosome to Golgi; GO:0042110 (0.01) ! T cell activation; GO:0040014 (0.01) ! regulation of multicellular organism growth; GO:0035914 (0.01) ! skeletal muscle cell differentiation; GO:0035907 (0.01) ! dorsal aorta development; GO:0035295 (0.01) ! tube development; GO:0035148 (0.01) ! tube formation; GO:0035066 (0.01) ! positive regulation of histone acetylation; GO:0034644 (0.01) ! cellular response to UV; GO:0033962 (0.01) ! cytoplasmic mRNA processing body assembly; GO:0033132 (0.01) ! negative regulation of glucokinase activity; GO:0032786 (0.01) ! positive regulation of DNA-templated transcription, elongation; GO:0032535 (0.01) ! regulation of cellular component size; GO:0032101 (0.01) ! regulation of response to external stimulus; GO:0031123 (0.01) ! RNA 3'-end processing; GO:0031101 (0.01) ! fin regeneration; GO:0031063 (0.01) ! regulation of histone deacetylation; GO:0031032 (0.01) ! actomyosin structure organization; GO:0030900 (0.01) ! forebrain development; GO:0030865 (0.01) ! cortical cytoskeleton organization; GO:0030855 (0.01) ! epithelial cell differentiation; GO:0030705 (0.01) ! cytoskeleton-dependent intracellular transport; GO:0030521 (0.01) ! androgen receptor signaling pathway; GO:0030520 (0.01) ! intracellular estrogen receptor signaling pathway; GO:0030512 (0.01) ! negative regulation of transforming growth factor beta receptor signaling pathway; GO:0030431 (0.01) ! sleep; GO:0030336 (0.01) ! negative regulation of cell migration; GO:0030326 (0.01) ! embryonic limb morphogenesis; GO:0030324 (0.01) ! lung development; GO:0030308 (0.01) ! negative regulation of cell growth; GO:0030258 (0.01) ! lipid modification; GO:0030183 (0.01) ! B cell differentiation; GO:0030111 (0.01) ! regulation of Wnt signaling pathway; GO:0030099 (0.01) ! myeloid cell differentiation; GO:0030031 (0.01) ! cell projection assembly; GO:0022008 (0.01) ! neurogenesis; GO:0021654 (0.01) ! rhombomere boundary formation; GO:0021591 (0.01) ! ventricular system development; GO:0021514 (0.01) ! ventral spinal cord interneuron differentiation; GO:0019730 (0.01) ! antimicrobial humoral response; GO:0019233 (0.01) ! sensory perception of pain; GO:0018076 (0.01) ! N-terminal peptidyl-lysine acetylation; GO:0016925 (0.01) ! protein sumoylation; GO:0016322 (0.01) ! neuron remodeling; GO:0016049 (0.01) ! cell growth; GO:0016032 (0.01) ! viral process; GO:0010923 (0.01) ! negative regulation of phosphatase activity; GO:0010830 (0.01) ! regulation of myotube differentiation; GO:0010770 (0.01) ! positive regulation of cell morphogenesis involved in differentiation; GO:0010501 (0.01) ! RNA secondary structure unwinding; GO:0010038 (0.01) ! response to metal ion; GO:0010001 (0.01) ! glial cell differentiation; GO:0009953 (0.01) ! dorsal/ventral pattern formation; GO:0009582 (0.01) ! detection of abiotic stimulus; GO:0009581 (0.01) ! detection of external stimulus; GO:0009408 (0.01) ! response to heat; GO:0009303 (0.01) ! rRNA transcription; GO:0008582 (0.01) ! regulation of synaptic growth at neuromuscular junction; GO:0008340 (0.01) ! determination of adult lifespan; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008217 (0.01) ! regulation of blood pressure; GO:0007623 (0.01) ! circadian rhythm; GO:0007616 (0.01) ! long-term memory; GO:0007605 (0.01) ! sensory perception of sound; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007498 (0.01) ! mesoderm development; GO:0007492 (0.01) ! endoderm development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007417 (0.01) ! central nervous system development; GO:0007411 (0.01) ! axon guidance; GO:0007399 (0.01) ! nervous system development; GO:0007368 (0.01) ! determination of left/right symmetry; GO:0007350 (0.01) ! blastoderm segmentation; GO:0007298 (0.01) ! border follicle cell migration; GO:0007286 (0.01) ! spermatid development; GO:0007283 (0.01) ! spermatogenesis; GO:0007268 (0.01) ! chemical synaptic transmission; GO:0007162 (0.01) ! negative regulation of cell adhesion; GO:0007051 (0.01) ! spindle organization; GO:0007030 (0.01) ! Golgi organization; GO:0007018 (0.01) ! microtubule-based movement; GO:0007015 (0.01) ! actin filament organization; GO:0006915 (0.01) ! apoptotic process; GO:0006909 (0.01) ! phagocytosis; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006887 (0.01) ! exocytosis; GO:0006836 (0.01) ! neurotransmitter transport; GO:0006607 (0.01) ! NLS-bearing protein import into nucleus; GO:0006511 (0.01) ! ubiquitin-dependent protein catabolic process; GO:0006417 (0.01) ! regulation of translation; GO:0006406 (0.01) ! mRNA export from nucleus; GO:0006342 (0.01) ! chromatin silencing; GO:0006337 (0.01) ! nucleosome disassembly; GO:0006306 (0.01) ! DNA methylation; GO:0006275 (0.01) ! regulation of DNA replication; GO:0003007 (0.01) ! heart morphogenesis; GO:0002833 (0.01) ! positive regulation of response to biotic stimulus; GO:0002761 (0.01) ! regulation of myeloid leukocyte differentiation; GO:0002697 (0.01) ! regulation of immune effector process; GO:0002252 (0.01) ! immune effector process; GO:0002064 (0.01) ! epithelial cell development; GO:0001947 (0.01) ! heart looping; GO:0001946 (0.01) ! lymphangiogenesis; GO:0001932 (0.01) ! regulation of protein phosphorylation; GO:0001892 (0.01) ! embryonic placenta development; GO:0001889 (0.01) ! liver development; GO:0001837 (0.01) ! epithelial to mesenchymal transition; GO:0001822 (0.01) ! kidney development; GO:0001817 (0.01) ! regulation of cytokine production; GO:0001756 (0.01) ! somitogenesis; GO:0001701 (0.01) ! in utero embryonic development; GO:0001505 (0.01) ! regulation of neurotransmitter levels; GO:0001501 (0.01) ! skeletal system development; GO:0000290 (0.01) ! deadenylation-dependent decapping of nuclear-transcribed mRNA; GO:0000209 (0.01) ! protein polyubiquitination GO:0005654 (1.00) ! nucleoplasm GO:0005654 ! nucleoplasm 2 28755978-28855232 (17q11.2) High: stomach 2 (glandular cells);fallopian tube (glandular cells);urinary bladder (urothelial cells);small intestine (glandular cells);colon (glandular cells);gallbladder (glandular cells);rectum (glandular cells);duodenum (glandular cells);Medium: stomach 1 (glandular cells);seminal vesicle (glandular cells);lung (macrophages);esophagus (squamous epithelial cells);kidney (cells in glomeruli; cells in tubules);testis (cells in seminiferous ducts; Leydig cells);tonsil (germinal center cells; non-germinal center cells; squamous epithelial cells);endometrium 2 (cells in endometrial stroma; glandular cells);epididymis (glandular cells);endometrium 1 (glandular cells);thyroid gland (glandular cells);salivary gland (glandular cells);vagina (squamous epithelial cells);cerebral cortex (neuronal cells);hippocampus (glial cells; neuronal cells);bronchus (respiratory epithelial cells);parathyroid gland (glandular cells);appendix (glandular cells);breast (glandular cells; myoepithelial cells);prostate (glandular cells);cervix, uterine (glandular cells; squamous epithelial cells);pancreas (exocrine glandular cells; islets of Langerhans);cerebellum (Purkinje cells);nasopharynx (respiratory epithelial cells);Low: cerebellum (cells in granular layer);lymph node (germinal center cells; non-germinal center cells);placenta (decidual cells);caudate (neuronal cells);bone marrow (hematopoietic cells);adrenal gland (glandular cells);colon (endothelial cells);skin 1 (fibroblasts; keratinocytes; Langerhans; melanocytes);lung (pneumocytes);oral mucosa (squamous epithelial cells);cerebral cortex (endothelial cells);smooth muscle (smooth muscle cells);skin 2 (epidermal cells); Testis: 48.34; Brain - Cerebellar Hemisphere: 22.43; Muscle - Skeletal: 21.75; Brain - Cerebellum: 20.01; Esophagus - Muscularis: 19.35; Bladder: 17.00; Esophagus - Gastroesophageal Junction: 15.90; Pituitary: 15.48; Cervix - Endocervix: 15.15; Minor Salivary Gland: 14.29; Prostate: 14.15; Vagina: 13.69; Artery - Tibial: 13.63; Thyroid: 13.61; Cervix - Ectocervix: 12.95; Colon - Sigmoid: 12.72; Ovary: 12.24; Small Intestine - Terminal Ileum: 12.15; Lung: 12.14; Artery - Aorta: 12.04; Uterus: 12.01; Artery - Coronary: 11.92; Esophagus - Mucosa: 11.85; Colon - Transverse: 11.76; Breast - Mammary Tissue: 11.73; Nerve - Tibial: 11.37; Adipose - Subcutaneous: 11.36; Cells - Transformed fibroblasts: 11.08; Fallopian Tube: 10.93; Adipose - Visceral (Omentum): 10.01; Skin - Sun Exposed (Lower leg): 9.92; Brain - Frontal Cortex (BA9): 9.73; Cells - EBV-transformed lymphocytes: 9.47; Kidney - Cortex: 9.39; Skin - Not Sun Exposed (Suprapubic): 9.21; Spleen: 8.99; Brain - Spinal cord (cervical c-1): 8.69; Brain - Cortex: 8.41; Brain - Nucleus accumbens (basal ganglia): 7.63; Brain - Hypothalamus: 7.60; Brain - Caudate (basal ganglia): 7.27; Stomach: 7.10; Brain - Substantia nigra: 6.84; Adrenal Gland: 6.82; Brain - Anterior cingulate cortex (BA24): 6.80; Brain - Putamen (basal ganglia): 6.19; Heart - Atrial Appendage: 6.19; Brain - Hippocampus: 6.04; Brain - Amygdala: 5.93; Heart - Left Ventricle: 5.21; Pancreas: 4.18; Liver: 4.02; Whole Blood: 3.59; MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCAAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRAPGNRAPDPTESRSLHIQHPGYR EFCAB5 EF-hand calcium-binding domain-containing protein 5 EFCB5_HUMAN (A4FU69-1) GO:0003824 (0.32) ! catalytic activity; GO:0005198 (0.19) ! structural molecule activity; GO:1901363 (0.17) ! heterocyclic compound binding; GO:0097159 (0.17) ! organic cyclic compound binding; GO:0016787 (0.16) ! hydrolase activity; GO:0016740 (0.16) ! transferase activity; GO:0008092 (0.16) ! cytoskeletal protein binding; GO:0005102 (0.14) ! receptor binding; GO:0003676 (0.14) ! nucleic acid binding; GO:0016887 (0.13) ! ATPase activity; GO:0046789 (0.10) ! host cell surface receptor binding; GO:0044877 (0.10) ! macromolecular complex binding; GO:0004674 (0.10) ! protein serine/threonine kinase activity; GO:0032403 (0.09) ! protein complex binding; GO:0003774 (0.09) ! motor activity; GO:0003723 (0.09) ! RNA binding; GO:0019899 (0.07) ! enzyme binding; GO:0003779 (0.07) ! actin binding; GO:0098772 (0.06) ! molecular function regulator; GO:0044822 (0.06) ! poly(A) RNA binding; GO:0030674 (0.06) ! protein binding, bridging; GO:0005201 (0.06) ! extracellular matrix structural constituent; GO:0003777 (0.06) ! microtubule motor activity; GO:0051015 (0.05) ! actin filament binding; GO:0042623 (0.05) ! ATPase activity, coupled; GO:0005215 (0.05) ! transporter activity; GO:0005200 (0.05) ! structural constituent of cytoskeleton; GO:0004871 (0.05) ! signal transducer activity; GO:0046872 (0.04) ! metal ion binding; GO:0042802 (0.04) ! identical protein binding; GO:0030507 (0.04) ! spectrin binding; GO:0030234 (0.04) ! enzyme regulator activity; GO:0022892 (0.04) ! substrate-specific transporter activity; GO:0022857 (0.04) ! transmembrane transporter activity; GO:0019900 (0.04) ! kinase binding; GO:0008307 (0.04) ! structural constituent of muscle; GO:0008093 (0.04) ! cytoskeletal adaptor activity; GO:0005524 (0.04) ! ATP binding; GO:0004702 (0.04) ! receptor signaling protein serine/threonine kinase activity; GO:0003743 (0.04) ! translation initiation factor activity; GO:0042803 (0.03) ! protein homodimerization activity; GO:0030506 (0.03) ! ankyrin binding; GO:0019901 (0.03) ! protein kinase binding; GO:0015075 (0.03) ! ion transmembrane transporter activity; GO:0005096 (0.03) ! GTPase activator activity; GO:0004842 (0.03) ! ubiquitin-protein transferase activity; GO:0004687 (0.03) ! myosin light chain kinase activity; GO:0004683 (0.03) ! calmodulin-dependent protein kinase activity; GO:0003677 (0.03) ! DNA binding; GO:0097493 (0.02) ! structural molecule activity conferring elasticity; GO:0051371 (0.02) ! muscle alpha-actinin binding; GO:0046873 (0.02) ! metal ion transmembrane transporter activity; GO:0044212 (0.02) ! transcription regulatory region DNA binding; GO:0043531 (0.02) ! ADP binding; GO:0030898 (0.02) ! actin-dependent ATPase activity; GO:0030332 (0.02) ! cyclin binding; GO:0022804 (0.02) ! active transmembrane transporter activity; GO:0019215 (0.02) ! intermediate filament binding; GO:0017016 (0.02) ! Ras GTPase binding; GO:0008757 (0.02) ! S-adenosylmethionine-dependent methyltransferase activity; GO:0008134 (0.02) ! transcription factor binding; GO:0008094 (0.02) ! DNA-dependent ATPase activity; GO:0008017 (0.02) ! microtubule binding; GO:0005509 (0.02) ! calcium ion binding; GO:0005216 (0.02) ! ion channel activity; GO:0003682 (0.02) ! chromatin binding; GO:0001664 (0.02) ! G-protein coupled receptor binding; GO:0000981 (0.02) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0000146 (0.02) ! microfilament motor activity; GO:0098641 (0.01) ! cadherin binding involved in cell-cell adhesion; GO:0097110 (0.01) ! scaffold protein binding; GO:0071889 (0.01) ! 14-3-3 protein binding; GO:0070975 (0.01) ! FHA domain binding; GO:0051117 (0.01) ! ATPase binding; GO:0047485 (0.01) ! protein N-terminus binding; GO:0046965 (0.01) ! retinoid X receptor binding; GO:0044325 (0.01) ! ion channel binding; GO:0043565 (0.01) ! sequence-specific DNA binding; GO:0043495 (0.01) ! protein anchor; GO:0043141 (0.01) ! ATP-dependent 5'-3' DNA helicase activity; GO:0042826 (0.01) ! histone deacetylase binding; GO:0035259 (0.01) ! glucocorticoid receptor binding; GO:0032027 (0.01) ! myosin light chain binding; GO:0031762 (0.01) ! follicle-stimulating hormone receptor binding; GO:0031730 (0.01) ! CCR5 chemokine receptor binding; GO:0019902 (0.01) ! phosphatase binding; GO:0017137 (0.01) ! Rab GTPase binding; GO:0016922 (0.01) ! ligand-dependent nuclear receptor binding; GO:0016788 (0.01) ! hydrolase activity, acting on ester bonds; GO:0015293 (0.01) ! symporter activity; GO:0010521 (0.01) ! telomerase inhibitor activity; GO:0008574 (0.01) ! ATP-dependent microtubule motor activity, plus-end-directed; GO:0008565 (0.01) ! protein transporter activity; GO:0008270 (0.01) ! zinc ion binding; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005544 (0.01) ! calcium-dependent phospholipid binding; GO:0005539 (0.01) ! glycosaminoglycan binding; GO:0005522 (0.01) ! profilin binding; GO:0005391 (0.01) ! sodium:potassium-exchanging ATPase activity; GO:0005262 (0.01) ! calcium channel activity; GO:0005254 (0.01) ! chloride channel activity; GO:0005199 (0.01) ! structural constituent of cell wall; GO:0005085 (0.01) ! guanyl-nucleotide exchange factor activity; GO:0005080 (0.01) ! protein kinase C binding; GO:0004872 (0.01) ! receptor activity; GO:0004550 (0.01) ! nucleoside diphosphate kinase activity; GO:0004364 (0.01) ! glutathione transferase activity; GO:0004198 (0.01) ! calcium-dependent cysteine-type endopeptidase activity; GO:0004127 (0.01) ! cytidylate kinase activity; GO:0004017 (0.01) ! adenylate kinase activity; GO:0003714 (0.01) ! transcription corepressor activity; GO:0003690 (0.01) ! double-stranded DNA binding; GO:0001012 (0.01) ! RNA polymerase II regulatory region DNA binding; GO:0000287 (0.01) ! magnesium ion binding GO:0009987 (0.71) ! cellular process; GO:0044699 (0.66) ! single-organism process; GO:0044763 (0.50) ! single-organism cellular process; GO:0016043 (0.40) ! cellular component organization; GO:0065007 (0.38) ! biological regulation; GO:0032502 (0.32) ! developmental process; GO:0050789 (0.31) ! regulation of biological process; GO:0044767 (0.31) ! single-organism developmental process; GO:0050794 (0.30) ! regulation of cellular process; GO:0048856 (0.23) ! anatomical structure development; GO:0008152 (0.23) ! metabolic process; GO:0006996 (0.23) ! organelle organization; GO:1902589 (0.21) ! single-organism organelle organization; GO:0007010 (0.21) ! cytoskeleton organization; GO:0071704 (0.20) ! organic substance metabolic process; GO:0044237 (0.20) ! cellular metabolic process; GO:0032501 (0.20) ! multicellular organismal process; GO:0022607 (0.20) ! cellular component assembly; GO:0044238 (0.19) ! primary metabolic process; GO:0051179 (0.18) ! localization; GO:0043170 (0.18) ! macromolecule metabolic process; GO:0044260 (0.17) ! cellular macromolecule metabolic process; GO:0030029 (0.15) ! actin filament-based process; GO:0065008 (0.14) ! regulation of biological quality; GO:0030036 (0.14) ! actin cytoskeleton organization; GO:0019222 (0.14) ! regulation of metabolic process; GO:0009653 (0.14) ! anatomical structure morphogenesis; GO:0006928 (0.14) ! movement of cell or subcellular component; GO:0006810 (0.14) ! transport; GO:0080090 (0.13) ! regulation of primary metabolic process; GO:0050896 (0.13) ! response to stimulus; GO:0048646 (0.13) ! anatomical structure formation involved in morphogenesis; GO:0043933 (0.13) ! macromolecular complex subunit organization; GO:0031323 (0.13) ! regulation of cellular metabolic process; GO:0065003 (0.12) ! macromolecular complex assembly; GO:0048869 (0.12) ! cellular developmental process; GO:0016337 (0.12) ! single organismal cell-cell adhesion; GO:0010927 (0.12) ! cellular component assembly involved in morphogenesis; GO:0003008 (0.12) ! system process; GO:0060255 (0.11) ! regulation of macromolecule metabolic process; GO:0048523 (0.11) ! negative regulation of cellular process; GO:0048518 (0.11) ! positive regulation of biological process; GO:0044707 (0.11) ! single-multicellular organism process; GO:0034622 (0.11) ! cellular macromolecular complex assembly; GO:0019538 (0.11) ! protein metabolic process; GO:0051128 (0.10) ! regulation of cellular component organization; GO:0007017 (0.10) ! microtubule-based process; GO:0006464 (0.10) ! cellular protein modification process; GO:1902578 (0.09) ! single-organism localization; GO:0048522 (0.09) ! positive regulation of cellular process; GO:0032879 (0.09) ! regulation of localization; GO:0030030 (0.09) ! cell projection organization; GO:0008104 (0.09) ! protein localization; GO:0006950 (0.09) ! response to stress; GO:2000112 (0.08) ! regulation of cellular macromolecule biosynthetic process; GO:0051641 (0.08) ! cellular localization; GO:0051239 (0.08) ! regulation of multicellular organismal process; GO:0048731 (0.08) ! system development; GO:0048513 (0.08) ! animal organ development; GO:0034641 (0.08) ! cellular nitrogen compound metabolic process; GO:0031032 (0.08) ! actomyosin structure organization; GO:0019219 (0.08) ! regulation of nucleobase-containing compound metabolic process; GO:0006461 (0.08) ! protein complex assembly; GO:0090304 (0.07) ! nucleic acid metabolic process; GO:0071702 (0.07) ! organic substance transport; GO:0051716 (0.07) ! cellular response to stimulus; GO:0046907 (0.07) ! intracellular transport; GO:0044765 (0.07) ! single-organism transport; GO:0031034 (0.07) ! myosin filament assembly; GO:0010468 (0.07) ! regulation of gene expression; GO:0061024 (0.06) ! membrane organization; GO:0051252 (0.06) ! regulation of RNA metabolic process; GO:0050793 (0.06) ! regulation of developmental process; GO:0040011 (0.06) ! locomotion; GO:0033554 (0.06) ! cellular response to stress; GO:0022414 (0.06) ! reproductive process; GO:0016310 (0.06) ! phosphorylation; GO:0015031 (0.06) ! protein transport; GO:0010604 (0.06) ! positive regulation of macromolecule metabolic process; GO:0009886 (0.06) ! post-embryonic morphogenesis; GO:0007519 (0.06) ! skeletal muscle tissue development; GO:0007154 (0.06) ! cell communication; GO:0007018 (0.06) ! microtubule-based movement; GO:0007015 (0.06) ! actin filament organization; GO:0006936 (0.06) ! muscle contraction; GO:0090066 (0.05) ! regulation of anatomical structure size; GO:0071688 (0.05) ! striated muscle myosin thick filament assembly; GO:0065009 (0.05) ! regulation of molecular function; GO:0051049 (0.05) ! regulation of transport; GO:0050877 (0.05) ! neurological system process; GO:0048870 (0.05) ! cell motility; GO:0044702 (0.05) ! single organism reproductive process; GO:0044700 (0.05) ! single organism signaling; GO:0034613 (0.05) ! cellular protein localization; GO:0033043 (0.05) ! regulation of organelle organization; GO:0031325 (0.05) ! positive regulation of cellular metabolic process; GO:0031324 (0.05) ! negative regulation of cellular metabolic process; GO:0030240 (0.05) ! skeletal muscle thin filament assembly; GO:0030239 (0.05) ! myofibril assembly; GO:0023051 (0.05) ! regulation of signaling; GO:0022402 (0.05) ! cell cycle process; GO:0016192 (0.05) ! vesicle-mediated transport; GO:0010646 (0.05) ! regulation of cell communication; GO:0010605 (0.05) ! negative regulation of macromolecule metabolic process; GO:0009605 (0.05) ! response to external stimulus; GO:0007610 (0.05) ! behavior; GO:0007420 (0.05) ! brain development; GO:0006941 (0.05) ! striated muscle contraction; GO:0006886 (0.05) ! intracellular protein transport; GO:0006468 (0.05) ! protein phosphorylation; GO:0006357 (0.05) ! regulation of transcription from RNA polymerase II promoter; GO:0001654 (0.05) ! eye development; GO:0000226 (0.05) ! microtubule cytoskeleton organization; GO:2000113 (0.04) ! negative regulation of cellular macromolecule biosynthetic process; GO:1903047 (0.04) ! mitotic cell cycle process; GO:1902582 (0.04) ! single-organism intracellular transport; GO:0051270 (0.04) ! regulation of cellular component movement; GO:0051130 (0.04) ! positive regulation of cellular component organization; GO:0050790 (0.04) ! regulation of catalytic activity; GO:0048598 (0.04) ! embryonic morphogenesis; GO:0046331 (0.04) ! lateral inhibition; GO:0045935 (0.04) ! positive regulation of nucleobase-containing compound metabolic process; GO:0045934 (0.04) ! negative regulation of nucleobase-containing compound metabolic process; GO:0045214 (0.04) ! sarcomere organization; GO:0044802 (0.04) ! single-organism membrane organization; GO:0044719 (0.04) ! regulation of imaginal disc-derived wing size; GO:0044087 (0.04) ! regulation of cellular component biogenesis; GO:0044057 (0.04) ! regulation of system process; GO:0043010 (0.04) ! camera-type eye development; GO:0042981 (0.04) ! regulation of apoptotic process; GO:0042221 (0.04) ! response to chemical; GO:0040005 (0.04) ! chitin-based cuticle attachment to epithelium; GO:0032970 (0.04) ! regulation of actin filament-based process; GO:0031444 (0.04) ! slow-twitch skeletal muscle fiber contraction; GO:0031328 (0.04) ! positive regulation of cellular biosynthetic process; GO:0031175 (0.04) ! neuron projection development; GO:0030154 (0.04) ! cell differentiation; GO:0022618 (0.04) ! ribonucleoprotein complex assembly; GO:0016477 (0.04) ! cell migration; GO:0010557 (0.04) ! positive regulation of macromolecule biosynthetic process; GO:0009611 (0.04) ! response to wounding; GO:0008362 (0.04) ! chitin-based embryonic cuticle biosynthetic process; GO:0007475 (0.04) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.04) ! open tracheal system development; GO:0007411 (0.04) ! axon guidance; GO:0006396 (0.04) ! RNA processing; GO:2000026 (0.03) ! regulation of multicellular organismal development; GO:0098901 (0.03) ! regulation of cardiac muscle cell action potential; GO:0086004 (0.03) ! regulation of cardiac muscle cell contraction; GO:0072661 (0.03) ! protein targeting to plasma membrane; GO:0051704 (0.03) ! multi-organism process; GO:0051493 (0.03) ! regulation of cytoskeleton organization; GO:0051336 (0.03) ! regulation of hydrolase activity; GO:0048638 (0.03) ! regulation of developmental growth; GO:0048583 (0.03) ! regulation of response to stimulus; GO:0048468 (0.03) ! cell development; GO:0045892 (0.03) ! negative regulation of transcription, DNA-templated; GO:0043066 (0.03) ! negative regulation of apoptotic process; GO:0042391 (0.03) ! regulation of membrane potential; GO:0042127 (0.03) ! regulation of cell proliferation; GO:0034330 (0.03) ! cell junction organization; GO:0032989 (0.03) ! cellular component morphogenesis; GO:0032268 (0.03) ! regulation of cellular protein metabolic process; GO:0031103 (0.03) ! axon regeneration; GO:0030031 (0.03) ! cell projection assembly; GO:0019233 (0.03) ! sensory perception of pain; GO:0010906 (0.03) ! regulation of glucose metabolic process; GO:0010638 (0.03) ! positive regulation of organelle organization; GO:0010628 (0.03) ! positive regulation of gene expression; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0007626 (0.03) ! locomotory behavior; GO:0007417 (0.03) ! central nervous system development; GO:0007165 (0.03) ! signal transduction; GO:0006897 (0.03) ! endocytosis; GO:0001732 (0.03) ! formation of cytoplasmic translation initiation complex; GO:0000375 (0.03) ! RNA splicing, via transesterification reactions; GO:2000179 (0.02) ! positive regulation of neural precursor cell proliferation; GO:1903530 (0.02) ! regulation of secretion by cell; GO:1902532 (0.02) ! negative regulation of intracellular signal transduction; GO:1901576 (0.02) ! organic substance biosynthetic process; GO:0098910 (0.02) ! regulation of atrial cardiac muscle cell action potential; GO:0071496 (0.02) ! cellular response to external stimulus; GO:0060627 (0.02) ! regulation of vesicle-mediated transport; GO:0060341 (0.02) ! regulation of cellular localization; GO:0060041 (0.02) ! retina development in camera-type eye; GO:0055085 (0.02) ! transmembrane transport; GO:0055008 (0.02) ! cardiac muscle tissue morphogenesis; GO:0051707 (0.02) ! response to other organism; GO:0051457 (0.02) ! maintenance of protein location in nucleus; GO:0051240 (0.02) ! positive regulation of multicellular organismal process; GO:0051050 (0.02) ! positive regulation of transport; GO:0048884 (0.02) ! neuromast development; GO:0048703 (0.02) ! embryonic viscerocranium morphogenesis; GO:0048639 (0.02) ! positive regulation of developmental growth; GO:0045893 (0.02) ! positive regulation of transcription, DNA-templated; GO:0045109 (0.02) ! intermediate filament organization; GO:0044710 (0.02) ! single-organism metabolic process; GO:0044351 (0.02) ! macropinocytosis; GO:0044249 (0.02) ! cellular biosynthetic process; GO:0044093 (0.02) ! positive regulation of molecular function; GO:0043087 (0.02) ! regulation of GTPase activity; GO:0042787 (0.02) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0042592 (0.02) ! homeostatic process; GO:0042461 (0.02) ! photoreceptor cell development; GO:0035107 (0.02) ! appendage morphogenesis; GO:0035082 (0.02) ! axoneme assembly; GO:0033044 (0.02) ! regulation of chromosome organization; GO:0032880 (0.02) ! regulation of protein localization; GO:0032844 (0.02) ! regulation of homeostatic process; GO:0032298 (0.02) ! positive regulation of DNA-dependent DNA replication initiation; GO:0032270 (0.02) ! positive regulation of cellular protein metabolic process; GO:0032259 (0.02) ! methylation; GO:0031667 (0.02) ! response to nutrient levels; GO:0031581 (0.02) ! hemidesmosome assembly; GO:0031399 (0.02) ! regulation of protein modification process; GO:0031076 (0.02) ! embryonic camera-type eye development; GO:0030900 (0.02) ! forebrain development; GO:0030855 (0.02) ! epithelial cell differentiation; GO:0030844 (0.02) ! positive regulation of intermediate filament depolymerization; GO:0030048 (0.02) ! actin filament-based movement; GO:0022604 (0.02) ! regulation of cell morphogenesis; GO:0021558 (0.02) ! trochlear nerve development; GO:0021557 (0.02) ! oculomotor nerve development; GO:0021554 (0.02) ! optic nerve development; GO:0019220 (0.02) ! regulation of phosphate metabolic process; GO:0016203 (0.02) ! muscle attachment; GO:0016050 (0.02) ! vesicle organization; GO:0010639 (0.02) ! negative regulation of organelle organization; GO:0009887 (0.02) ! organ morphogenesis; GO:0008582 (0.02) ! regulation of synaptic growth at neuromuscular junction; GO:0008045 (0.02) ! motor neuron axon guidance; GO:0007611 (0.02) ! learning or memory; GO:0007422 (0.02) ! peripheral nervous system development; GO:0007409 (0.02) ! axonogenesis; GO:0007298 (0.02) ! border follicle cell migration; GO:0007275 (0.02) ! multicellular organism development; GO:0007163 (0.02) ! establishment or maintenance of cell polarity; GO:0006974 (0.02) ! cellular response to DNA damage stimulus; GO:0006888 (0.02) ! ER to Golgi vesicle-mediated transport; GO:0006811 (0.02) ! ion transport; GO:0006325 (0.02) ! chromatin organization; GO:0006259 (0.02) ! DNA metabolic process; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0003002 (0.02) ! regionalization; GO:0000910 (0.02) ! cytokinesis; GO:0000398 (0.02) ! mRNA splicing, via spliceosome; GO:0000122 (0.02) ! negative regulation of transcription from RNA polymerase II promoter; GO:2001259 (0.01) ! positive regulation of cation channel activity; GO:2000241 (0.01) ! regulation of reproductive process; GO:2000142 (0.01) ! regulation of DNA-templated transcription, initiation; GO:1903923 (0.01) ! positive regulation of protein processing in phagocytic vesicle; GO:1903919 (0.01) ! negative regulation of actin filament severing; GO:1903046 (0.01) ! meiotic cell cycle process; GO:1902685 (0.01) ! positive regulation of receptor localization to synapse; GO:1902513 (0.01) ! regulation of organelle transport along microtubule; GO:1902476 (0.01) ! chloride transmembrane transport; GO:1901739 (0.01) ! regulation of myoblast fusion; GO:1901575 (0.01) ! organic substance catabolic process; GO:1901021 (0.01) ! positive regulation of calcium ion transmembrane transporter activity; GO:1901018 (0.01) ! positive regulation of potassium ion transmembrane transporter activity; GO:0098911 (0.01) ! regulation of ventricular cardiac muscle cell action potential; GO:0098907 (0.01) ! regulation of SA node cell action potential; GO:0098792 (0.01) ! xenophagy; GO:0098779 (0.01) ! mitophagy in response to mitochondrial depolarization; GO:0090630 (0.01) ! activation of GTPase activity; GO:0090164 (0.01) ! asymmetric Golgi ribbon formation; GO:0086091 (0.01) ! regulation of heart rate by cardiac conduction; GO:0086073 (0.01) ! bundle of His cell-Purkinje myocyte adhesion involved in cell communication; GO:0086070 (0.01) ! SA node cell to atrial cardiac muscle cell communication; GO:0086066 (0.01) ! atrial cardiac muscle cell to AV node cell communication; GO:0086015 (0.01) ! SA node cell action potential; GO:0086014 (0.01) ! atrial cardiac muscle cell action potential; GO:0086010 (0.01) ! membrane depolarization during action potential; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0075525 (0.01) ! viral translational termination-reinitiation; GO:0075522 (0.01) ! IRES-dependent viral translational initiation; GO:0071896 (0.01) ! protein localization to adherens junction; GO:0071705 (0.01) ! nitrogen compound transport; GO:0071310 (0.01) ! cellular response to organic substance; GO:0071260 (0.01) ! cellular response to mechanical stimulus; GO:0070986 (0.01) ! left/right axis specification; GO:0070972 (0.01) ! protein localization to endoplasmic reticulum; GO:0061025 (0.01) ! membrane fusion; GO:0060328 (0.01) ! cytoplasmic actin-based contraction involved in forward cell motility; GO:0060048 (0.01) ! cardiac muscle contraction; GO:0060047 (0.01) ! heart contraction; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051893 (0.01) ! regulation of focal adhesion assembly; GO:0051348 (0.01) ! negative regulation of transferase activity; GO:0051315 (0.01) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051259 (0.01) ! protein oligomerization; GO:0050821 (0.01) ! protein stabilization; GO:0050766 (0.01) ! positive regulation of phagocytosis; GO:0050714 (0.01) ! positive regulation of protein secretion; GO:0048813 (0.01) ! dendrite morphogenesis; GO:0048749 (0.01) ! compound eye development; GO:0048739 (0.01) ! cardiac muscle fiber development; GO:0048738 (0.01) ! cardiac muscle tissue development; GO:0048589 (0.01) ! developmental growth; GO:0048562 (0.01) ! embryonic organ morphogenesis; GO:0048211 (0.01) ! Golgi vesicle docking; GO:0048194 (0.01) ! Golgi vesicle budding; GO:0046847 (0.01) ! filopodium assembly; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046664 (0.01) ! dorsal closure, amnioserosa morphology change; GO:0046663 (0.01) ! dorsal closure, leading edge cell differentiation; GO:0046622 (0.01) ! positive regulation of organ growth; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045859 (0.01) ! regulation of protein kinase activity; GO:0045597 (0.01) ! positive regulation of cell differentiation; GO:0045200 (0.01) ! establishment of neuroblast polarity; GO:0045056 (0.01) ! transcytosis; GO:0044849 (0.01) ! estrous cycle; GO:0044271 (0.01) ! cellular nitrogen compound biosynthetic process; GO:0044089 (0.01) ! positive regulation of cellular component biogenesis; GO:0043588 (0.01) ! skin development; GO:0043534 (0.01) ! blood vessel endothelial cell migration; GO:0043524 (0.01) ! negative regulation of neuron apoptotic process; GO:0043414 (0.01) ! macromolecule methylation; GO:0042542 (0.01) ! response to hydrogen peroxide; GO:0042493 (0.01) ! response to drug; GO:0042060 (0.01) ! wound healing; GO:0036371 (0.01) ! protein localization to T-tubule; GO:0036309 (0.01) ! protein localization to M-band; GO:0035493 (0.01) ! SNARE complex assembly; GO:0035372 (0.01) ! protein localization to microtubule; GO:0035317 (0.01) ! imaginal disc-derived wing hair organization; GO:0035277 (0.01) ! spiracle morphogenesis, open tracheal system; GO:0035206 (0.01) ! regulation of hemocyte proliferation; GO:0035159 (0.01) ! regulation of tube length, open tracheal system; GO:0035112 (0.01) ! genitalia morphogenesis; GO:0035017 (0.01) ! cuticle pattern formation; GO:0034501 (0.01) ! protein localization to kinetochore; GO:0034461 (0.01) ! uropod retraction; GO:0034394 (0.01) ! protein localization to cell surface; GO:0034332 (0.01) ! adherens junction organization; GO:0033693 (0.01) ! neurofilament bundle assembly; GO:0033298 (0.01) ! contractile vacuole organization; GO:0033292 (0.01) ! T-tubule organization; GO:0033275 (0.01) ! actin-myosin filament sliding; GO:0032940 (0.01) ! secretion by cell; GO:0032355 (0.01) ! response to estradiol; GO:0032060 (0.01) ! bleb assembly; GO:0031532 (0.01) ! actin cytoskeleton reorganization; GO:0031400 (0.01) ! negative regulation of protein modification process; GO:0031338 (0.01) ! regulation of vesicle fusion; GO:0031297 (0.01) ! replication fork processing; GO:0031270 (0.01) ! pseudopodium retraction; GO:0031154 (0.01) ! culmination involved in sorocarp development; GO:0031152 (0.01) ! aggregation involved in sorocarp development; GO:0031134 (0.01) ! sister chromatid biorientation; GO:0031060 (0.01) ! regulation of histone methylation; GO:0031058 (0.01) ! positive regulation of histone modification; GO:0031036 (0.01) ! myosin II filament assembly; GO:0030866 (0.01) ! cortical actin cytoskeleton organization; GO:0030837 (0.01) ! negative regulation of actin filament polymerization; GO:0030431 (0.01) ! sleep; GO:0030334 (0.01) ! regulation of cell migration; GO:0030241 (0.01) ! skeletal muscle myosin thick filament assembly; GO:0030224 (0.01) ! monocyte differentiation; GO:0030220 (0.01) ! platelet formation; GO:0030216 (0.01) ! keratinocyte differentiation; GO:0030182 (0.01) ! neuron differentiation; GO:0030038 (0.01) ! contractile actin filament bundle assembly; GO:0022008 (0.01) ! neurogenesis; GO:0019730 (0.01) ! antimicrobial humoral response; GO:0018205 (0.01) ! peptidyl-lysine modification; GO:0018149 (0.01) ! peptide cross-linking; GO:0016575 (0.01) ! histone deacetylation; GO:0016322 (0.01) ! neuron remodeling; GO:0016266 (0.01) ! O-glycan processing; GO:0016080 (0.01) ! synaptic vesicle targeting; GO:0014866 (0.01) ! skeletal myofibril assembly; GO:0010923 (0.01) ! negative regulation of phosphatase activity; GO:0010881 (0.01) ! regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; GO:0010524 (0.01) ! positive regulation of calcium ion transport into cytosol; GO:0010243 (0.01) ! response to organonitrogen compound; GO:0010212 (0.01) ! response to ionizing radiation; GO:0009967 (0.01) ! positive regulation of signal transduction; GO:0009267 (0.01) ! cellular response to starvation; GO:0008360 (0.01) ! regulation of cell shape; GO:0008355 (0.01) ! olfactory learning; GO:0008340 (0.01) ! determination of adult lifespan; GO:0008283 (0.01) ! cell proliferation; GO:0008258 (0.01) ! head involution; GO:0008088 (0.01) ! axo-dendritic transport; GO:0008037 (0.01) ! cell recognition; GO:0007614 (0.01) ! short-term memory; GO:0007595 (0.01) ! lactation; GO:0007584 (0.01) ! response to nutrient; GO:0007565 (0.01) ! female pregnancy; GO:0007528 (0.01) ! neuromuscular junction development; GO:0007525 (0.01) ! somatic muscle development; GO:0007522 (0.01) ! visceral muscle development; GO:0007520 (0.01) ! myoblast fusion; GO:0007498 (0.01) ! mesoderm development; GO:0007496 (0.01) ! anterior midgut development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007443 (0.01) ! Malpighian tubule morphogenesis; GO:0007435 (0.01) ! salivary gland morphogenesis; GO:0007399 (0.01) ! nervous system development; GO:0007395 (0.01) ! dorsal closure, spreading of leading edge cells; GO:0007391 (0.01) ! dorsal closure; GO:0007379 (0.01) ! segment specification; GO:0007350 (0.01) ! blastoderm segmentation; GO:0007346 (0.01) ! regulation of mitotic cell cycle; GO:0007186 (0.01) ! G-protein coupled receptor signaling pathway; GO:0007076 (0.01) ! mitotic chromosome condensation; GO:0007062 (0.01) ! sister chromatid cohesion; GO:0007026 (0.01) ! negative regulation of microtubule depolymerization; GO:0006971 (0.01) ! hypotonic response; GO:0006952 (0.01) ! defense response; GO:0006935 (0.01) ! chemotaxis; GO:0006911 (0.01) ! phagocytosis, engulfment; GO:0006898 (0.01) ! receptor-mediated endocytosis; GO:0006892 (0.01) ! post-Golgi vesicle-mediated transport; GO:0006874 (0.01) ! cellular calcium ion homeostasis; GO:0006816 (0.01) ! calcium ion transport; GO:0006749 (0.01) ! glutathione metabolic process; GO:0006629 (0.01) ! lipid metabolic process; GO:0006509 (0.01) ! membrane protein ectodomain proteolysis; GO:0006364 (0.01) ! rRNA processing; GO:0006260 (0.01) ! DNA replication; GO:0003223 (0.01) ! ventricular compact myocardium morphogenesis; GO:0003007 (0.01) ! heart morphogenesis; GO:0002934 (0.01) ! desmosome organization; GO:0002230 (0.01) ! positive regulation of defense response to virus by host; GO:0001934 (0.01) ! positive regulation of protein phosphorylation; GO:0001736 (0.01) ! establishment of planar polarity; GO:0001701 (0.01) ! in utero embryonic development; GO:0001558 (0.01) ! regulation of cell growth; GO:0001525 (0.01) ! angiogenesis; GO:0000902 (0.01) ! cell morphogenesis; GO:0000281 (0.01) ! mitotic cytokinesis; GO:0000245 (0.01) ! spliceosomal complex assembly; GO:0000077 (0.01) ! DNA damage checkpoint GO:0044464 (0.81) ! cell part; GO:0044424 (0.74) ! intracellular part; GO:0044422 (0.46) ! organelle part; GO:0043226 (0.42) ! organelle; GO:0044446 (0.41) ! intracellular organelle part; GO:0043229 (0.40) ! intracellular organelle; GO:0043227 (0.34) ! membrane-bounded organelle; GO:0043231 (0.29) ! intracellular membrane-bounded organelle; GO:0044430 (0.26) ! cytoskeletal part; GO:0032991 (0.26) ! macromolecular complex; GO:0044444 (0.25) ! cytoplasmic part; GO:0043234 (0.24) ! protein complex; GO:0005634 (0.22) ! nucleus; GO:0005737 (0.21) ! cytoplasm; GO:0043232 (0.17) ! intracellular non-membrane-bounded organelle; GO:0016020 (0.14) ! membrane; GO:0044421 (0.13) ! extracellular region part; GO:0044428 (0.12) ! nuclear part; GO:0005875 (0.12) ! microtubule associated complex; GO:0020036 (0.11) ! Maurer's cleft; GO:0033644 (0.10) ! host cell membrane; GO:0031982 (0.10) ! vesicle; GO:0031988 (0.09) ! membrane-bounded vesicle; GO:0044449 (0.08) ! contractile fiber part; GO:0005856 (0.08) ! cytoskeleton; GO:0070062 (0.07) ! extracellular exosome; GO:0044425 (0.07) ! membrane part; GO:0030054 (0.07) ! cell junction; GO:0005886 (0.07) ! plasma membrane; GO:0005654 (0.07) ! nucleoplasm; GO:0031012 (0.06) ! extracellular matrix; GO:0044459 (0.05) ! plasma membrane part; GO:0044431 (0.05) ! Golgi apparatus part; GO:0005871 (0.05) ! kinesin complex; GO:0005829 (0.05) ! cytosol; GO:0099513 (0.04) ! polymeric cytoskeletal fiber; GO:0098791 (0.04) ! Golgi subcompartment; GO:0097458 (0.04) ! neuron part; GO:0070161 (0.04) ! anchoring junction; GO:0043034 (0.04) ! costamere; GO:0042995 (0.04) ! cell projection; GO:0042641 (0.04) ! actomyosin; GO:0030055 (0.04) ! cell-substrate junction; GO:0030018 (0.04) ! Z disc; GO:0016460 (0.04) ! myosin II complex; GO:0098805 (0.03) ! whole membrane; GO:0098588 (0.03) ! bounding membrane of organelle; GO:0044448 (0.03) ! cell cortex part; GO:0044441 (0.03) ! ciliary part; GO:0044427 (0.03) ! chromosomal part; GO:0042383 (0.03) ! sarcolemma; GO:0031430 (0.03) ! M band; GO:0031252 (0.03) ! cell leading edge; GO:0016023 (0.03) ! cytoplasmic, membrane-bounded vesicle; GO:0005925 (0.03) ! focal adhesion; GO:0005911 (0.03) ! cell-cell junction; GO:0005882 (0.03) ! intermediate filament; GO:0005852 (0.03) ! eukaryotic translation initiation factor 3 complex; GO:0005802 (0.03) ! trans-Golgi network; GO:0005773 (0.03) ! vacuole; GO:0005730 (0.03) ! nucleolus; GO:0005694 (0.03) ! chromosome; GO:1902494 (0.02) ! catalytic complex; GO:0098590 (0.02) ! plasma membrane region; GO:0070938 (0.02) ! contractile ring; GO:0048471 (0.02) ! perinuclear region of cytoplasm; GO:0045179 (0.02) ! apical cortex; GO:0045111 (0.02) ! intermediate filament cytoskeleton; GO:0044451 (0.02) ! nucleoplasm part; GO:0044437 (0.02) ! vacuolar part; GO:0044433 (0.02) ! cytoplasmic vesicle part; GO:0044291 (0.02) ! cell-cell contact zone; GO:0043292 (0.02) ! contractile fiber; GO:0032154 (0.02) ! cleavage furrow; GO:0031674 (0.02) ! I band; GO:0031672 (0.02) ! A band; GO:0031226 (0.02) ! intrinsic component of plasma membrane; GO:0030424 (0.02) ! axon; GO:0030056 (0.02) ! hemidesmosome; GO:0016021 (0.02) ! integral component of membrane; GO:0015630 (0.02) ! microtubule cytoskeleton; GO:0005930 (0.02) ! axoneme; GO:0005865 (0.02) ! striated muscle thin filament; GO:0005859 (0.02) ! muscle myosin complex; GO:0005783 (0.02) ! endoplasmic reticulum; GO:0005768 (0.02) ! endosome; GO:1990753 (0.01) ! equatorial cell cortex; GO:0098552 (0.01) ! side of membrane; GO:0097418 (0.01) ! neurofibrillary tangle; GO:0097204 (0.01) ! phagocytic cup base; GO:0045202 (0.01) ! synapse; GO:0044454 (0.01) ! nuclear chromosome part; GO:0044440 (0.01) ! endosomal part; GO:0044432 (0.01) ! endoplasmic reticulum part; GO:0043025 (0.01) ! neuronal cell body; GO:0035097 (0.01) ! histone methyltransferase complex; GO:0033267 (0.01) ! axon part; GO:0032009 (0.01) ! early phagosome; GO:0031254 (0.01) ! cell trailing edge; GO:0031143 (0.01) ! pseudopodium; GO:0030529 (0.01) ! intracellular ribonucleoprotein complex; GO:0030496 (0.01) ! midbody; GO:0030426 (0.01) ! growth cone; GO:0030425 (0.01) ! dendrite; GO:0030315 (0.01) ! T-tubule; GO:0030141 (0.01) ! secretory granule; GO:0030057 (0.01) ! desmosome; GO:0030017 (0.01) ! sarcomere; GO:0030016 (0.01) ! myofibril; GO:0019898 (0.01) ! extrinsic component of membrane; GO:0016528 (0.01) ! sarcoplasm; GO:0016461 (0.01) ! unconventional myosin complex; GO:0016328 (0.01) ! lateral plasma membrane; GO:0016324 (0.01) ! apical plasma membrane; GO:0016323 (0.01) ! basolateral plasma membrane; GO:0015629 (0.01) ! actin cytoskeleton; GO:0014704 (0.01) ! intercalated disc; GO:0014069 (0.01) ! postsynaptic density; GO:0012507 (0.01) ! ER to Golgi transport vesicle membrane; GO:0012505 (0.01) ! endomembrane system; GO:0009986 (0.01) ! cell surface; GO:0009925 (0.01) ! basal plasma membrane; GO:0008305 (0.01) ! integrin complex; GO:0005913 (0.01) ! cell-cell adherens junction; GO:0005903 (0.01) ! brush border; GO:0005887 (0.01) ! integral component of plasma membrane; GO:0005883 (0.01) ! neurofilament; GO:0005874 (0.01) ! microtubule; GO:0005863 (0.01) ! striated muscle myosin thick filament; GO:0005826 (0.01) ! actomyosin contractile ring; GO:0005819 (0.01) ! spindle; GO:0005813 (0.01) ! centrosome; GO:0005796 (0.01) ! Golgi lumen; GO:0005795 (0.01) ! Golgi stack; GO:0005794 (0.01) ! Golgi apparatus; GO:0005774 (0.01) ! vacuolar membrane; GO:0005739 (0.01) ! mitochondrion; GO:0005657 (0.01) ! replication fork; GO:0005622 (0.01) ! intracellular; GO:0005615 (0.01) ! extracellular space; GO:0001931 (0.01) ! uropod; GO:0001726 (0.01) ! ruffle; GO:0001725 (0.01) ! stress fiber; GO:0001533 (0.01) ! cornified envelope; GO:0000794 (0.01) ! condensed nuclear chromosome; GO:0000785 (0.01) ! chromatin; GO:0000777 (0.01) ! condensed chromosome kinetochore; GO:0000331 (0.01) ! contractile vacuole; GO:0000139 (0.01) ! Golgi membrane; GO:0000118 (0.01) ! histone deacetylase complex GO:0005509 ! calcium ion binding; GO:0046872 ! metal ion binding 3 GO:0005509 ! calcium ion binding 29929200-30108452 (17q11.2) Testis: 11.52; Brain - Cerebellar Hemisphere: 0.96; Brain - Cerebellum: 0.90; Brain - Frontal Cortex (BA9): 0.36; Nerve - Tibial: 0.31; Brain - Substantia nigra: 0.30; Brain - Cortex: 0.29; Brain - Anterior cingulate cortex (BA24): 0.24; Colon - Transverse: 0.23; Brain - Nucleus accumbens (basal ganglia): 0.21; Brain - Hypothalamus: 0.20; Brain - Spinal cord (cervical c-1): 0.20; Brain - Hippocampus: 0.20; Thyroid: 0.19; Small Intestine - Terminal Ileum: 0.19; Bladder: 0.17; Brain - Caudate (basal ganglia): 0.16; Spleen: 0.15; Brain - Amygdala: 0.15; Colon - Sigmoid: 0.14; Cells - Transformed fibroblasts: 0.14; Lung: 0.14; Brain - Putamen (basal ganglia): 0.13; Kidney - Cortex: 0.11; Skin - Sun Exposed (Lower leg): 0.11; Stomach: 0.10; Adipose - Subcutaneous: 0.09; Skin - Not Sun Exposed (Suprapubic): 0.09; Esophagus - Gastroesophageal Junction: 0.09; Cervix - Endocervix: 0.09; Esophagus - Muscularis: 0.09; Artery - Aorta: 0.08; Minor Salivary Gland: 0.08; Prostate: 0.08; Artery - Coronary: 0.08; Vagina: 0.08; Breast - Mammary Tissue: 0.08; Uterus: 0.08; Cervix - Ectocervix: 0.08; Fallopian Tube: 0.06; Artery - Tibial: 0.06; Cells - EBV-transformed lymphocytes: 0.06; Pituitary: 0.06; Adipose - Visceral (Omentum): 0.05; Whole Blood: 0.05; Adrenal Gland: 0.05; Muscle - Skeletal: 0.05; Heart - Atrial Appendage: 0.04; Esophagus - Mucosa: 0.04; Pancreas: 0.04; Ovary: 0.03; Heart - Left Ventricle: 0.03; Liver: 0.01; MNESASQEELRPAQENRKEDKERKWNLTEVKELHETLQSVPDVPVKEDTNSVVEKAMDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKKNLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLDKLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQRLMKEVTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIIVKVANTRKQALQEQFDEWILDPKGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYISSHIKDLKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLALLELFYDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEGKSWSGEFFTCNWKMKYVTFEDEEQANLIYGNSRFTDLHSIIRNIQSCKEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVSETLTSFFKEGYVETEQEKMNALEQFSQNAFQVRQRLLLEAIFQKWDSDGSGFLDLKEVDELLYTYKEGMEKESMKKAKLHIQFPKPHPGHEVRLSSKQFQNYIELVVSELRGNEDQVLESVVEFLMNALERSHIESLRNSARRKWLHQIQCAAETSGVSLEPVYSETFKALMQDAEAHGNKKISAHISLLEENLLLPEKGNVLLRNVACTLDDAQFVLNRVLYRDMKGISFTVVDEGKPIHVPQVQYHGNIFFWNQSRNKHDYNGSFLALPLQDAYMRIFGVLAVDTLRDPHEINIFLPHEIRFYQGVANVFSTAYHYVHSREHILHIVITGIGWLYDVTSSITSITTYFVEPSPAQDSDYVLRNMMVTGQLGLTEIHKNPPTIHRKSCIFRDFLFKCTDSSEVVLASACGETHIVVPLRERTGEALGVLDFNIGQNRMLLCQEYKDLQKMMKVVQVACYEILGEFSGEIKKKYILEIENVREVQRAGILFFRIMLLELQESIQLLNSMEFVSLLLYDHTLVTEPNSPQDSKSMELEANVKLVRDILKAVILFFHPELEFSSDFGSWDKCKFYVNKYLVNNICAFDPTAKHVEVNVQLIDEYIRDHSRTEVWKFGNVVIEHLYHWIHICSALMKITKQLNSGITPPLPSKTDNYMYAKMPGEGLQEK EVI2B EVI2B EVI2B_HUMAN (P34910-1) GO:0005198 (0.37) ! structural molecule activity; GO:0003824 (0.30) ! catalytic activity; GO:0016740 (0.17) ! transferase activity; GO:1901363 (0.13) ! heterocyclic compound binding; GO:0097159 (0.13) ! organic cyclic compound binding; GO:0016787 (0.12) ! hydrolase activity; GO:0016772 (0.11) ! transferase activity, transferring phosphorus-containing groups; GO:0003676 (0.11) ! nucleic acid binding; GO:0008092 (0.09) ! cytoskeletal protein binding; GO:0005215 (0.08) ! transporter activity; GO:0016773 (0.06) ! phosphotransferase activity, alcohol group as acceptor; GO:0016301 (0.06) ! kinase activity; GO:0008190 (0.06) ! eukaryotic initiation factor 4E binding; GO:0005201 (0.06) ! extracellular matrix structural constituent; GO:0003779 (0.06) ! actin binding; GO:0003723 (0.06) ! RNA binding; GO:0044877 (0.05) ! macromolecular complex binding; GO:0019899 (0.05) ! enzyme binding; GO:0016788 (0.05) ! hydrolase activity, acting on ester bonds; GO:0004842 (0.05) ! ubiquitin-protein transferase activity; GO:0004672 (0.05) ! protein kinase activity; GO:0003677 (0.05) ! DNA binding; GO:0098772 (0.04) ! molecular function regulator; GO:0044822 (0.04) ! poly(A) RNA binding; GO:0019901 (0.04) ! protein kinase binding; GO:0017111 (0.04) ! nucleoside-triphosphatase activity; GO:0016779 (0.04) ! nucleotidyltransferase activity; GO:0008017 (0.04) ! microtubule binding; GO:0005487 (0.04) ! nucleocytoplasmic transporter activity; GO:0004871 (0.04) ! signal transducer activity; GO:0004674 (0.04) ! protein serine/threonine kinase activity; GO:0003712 (0.04) ! transcription cofactor activity; GO:0097367 (0.03) ! carbohydrate derivative binding; GO:0046872 (0.03) ! metal ion binding; GO:0030234 (0.03) ! enzyme regulator activity; GO:0016887 (0.03) ! ATPase activity; GO:0008233 (0.03) ! peptidase activity; GO:0005261 (0.03) ! cation channel activity; GO:0004872 (0.03) ! receptor activity; GO:0003682 (0.03) ! chromatin binding; GO:0001104 (0.03) ! RNA polymerase II transcription cofactor activity; GO:0001055 (0.03) ! RNA polymerase II activity; GO:0070011 (0.02) ! peptidase activity, acting on L-amino acid peptides; GO:0043565 (0.02) ! sequence-specific DNA binding; GO:0032403 (0.02) ! protein complex binding; GO:0016791 (0.02) ! phosphatase activity; GO:0008307 (0.02) ! structural constituent of muscle; GO:0008134 (0.02) ! transcription factor binding; GO:0008094 (0.02) ! DNA-dependent ATPase activity; GO:0005543 (0.02) ! phospholipid binding; GO:0005509 (0.02) ! calcium ion binding; GO:0005262 (0.02) ! calcium channel activity; GO:0005102 (0.02) ! receptor binding; GO:0005096 (0.02) ! GTPase activator activity; GO:0004888 (0.02) ! transmembrane signaling receptor activity; GO:0004702 (0.02) ! receptor signaling protein serine/threonine kinase activity; GO:0002039 (0.02) ! p53 binding; GO:0000981 (0.02) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0000166 (0.02) ! nucleotide binding; GO:1901981 (0.01) ! phosphatidylinositol phosphate binding; GO:0097493 (0.01) ! structural molecule activity conferring elasticity; GO:0071949 (0.01) ! FAD binding; GO:0052689 (0.01) ! carboxylic ester hydrolase activity; GO:0051371 (0.01) ! muscle alpha-actinin binding; GO:0051019 (0.01) ! mitogen-activated protein kinase binding; GO:0051015 (0.01) ! actin filament binding; GO:0048495 (0.01) ! Roundabout binding; GO:0045296 (0.01) ! cadherin binding; GO:0043495 (0.01) ! protein anchor; GO:0043140 (0.01) ! ATP-dependent 3'-5' DNA helicase activity; GO:0042803 (0.01) ! protein homodimerization activity; GO:0035064 (0.01) ! methylated histone binding; GO:0034596 (0.01) ! phosphatidylinositol phosphate 4-phosphatase activity; GO:0033857 (0.01) ! diphosphoinositol-pentakisphosphate kinase activity; GO:0031402 (0.01) ! sodium ion binding; GO:0031072 (0.01) ! heat shock protein binding; GO:0030955 (0.01) ! potassium ion binding; GO:0030507 (0.01) ! spectrin binding; GO:0030506 (0.01) ! ankyrin binding; GO:0030197 (0.01) ! extracellular matrix constituent, lubricant activity; GO:0019904 (0.01) ! protein domain specific binding; GO:0019887 (0.01) ! protein kinase regulator activity; GO:0017154 (0.01) ! semaphorin receptor activity; GO:0017016 (0.01) ! Ras GTPase binding; GO:0016709 (0.01) ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; GO:0009378 (0.01) ! four-way junction helicase activity; GO:0008757 (0.01) ! S-adenosylmethionine-dependent methyltransferase activity; GO:0008273 (0.01) ! calcium, potassium:sodium antiporter activity; GO:0008237 (0.01) ! metallopeptidase activity; GO:0008201 (0.01) ! heparin binding; GO:0008170 (0.01) ! N-methyltransferase activity; GO:0008139 (0.01) ! nuclear localization sequence binding; GO:0008135 (0.01) ! translation factor activity, RNA binding; GO:0008093 (0.01) ! cytoskeletal adaptor activity; GO:0008022 (0.01) ! protein C-terminus binding; GO:0008013 (0.01) ! beta-catenin binding; GO:0005544 (0.01) ! calcium-dependent phospholipid binding; GO:0005528 (0.01) ! FK506 binding; GO:0005524 (0.01) ! ATP binding; GO:0005522 (0.01) ! profilin binding; GO:0005249 (0.01) ! voltage-gated potassium channel activity; GO:0005200 (0.01) ! structural constituent of cytoskeleton; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0004857 (0.01) ! enzyme inhibitor activity; GO:0004725 (0.01) ! protein tyrosine phosphatase activity; GO:0004713 (0.01) ! protein tyrosine kinase activity; GO:0004620 (0.01) ! phospholipase activity; GO:0004553 (0.01) ! hydrolase activity, hydrolyzing O-glycosyl compounds; GO:0004540 (0.01) ! ribonuclease activity; GO:0004439 (0.01) ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; GO:0004438 (0.01) ! phosphatidylinositol-3-phosphatase activity; GO:0004407 (0.01) ! histone deacetylase activity; GO:0004402 (0.01) ! histone acetyltransferase activity; GO:0004252 (0.01) ! serine-type endopeptidase activity; GO:0003964 (0.01) ! RNA-directed DNA polymerase activity; GO:0003887 (0.01) ! DNA-directed DNA polymerase activity; GO:0003777 (0.01) ! microtubule motor activity; GO:0003755 (0.01) ! peptidyl-prolyl cis-trans isomerase activity; GO:0003729 (0.01) ! mRNA binding; GO:0003713 (0.01) ! transcription coactivator activity; GO:0003684 (0.01) ! damaged DNA binding; GO:0001106 (0.01) ! RNA polymerase II transcription corepressor activity; GO:0001047 (0.01) ! core promoter binding; GO:0000987 (0.01) ! core promoter proximal region sequence-specific DNA binding; GO:0000977 (0.01) ! RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000829 (0.01) ! inositol heptakisphosphate kinase activity; GO:0000828 (0.01) ! inositol hexakisphosphate kinase activity GO:0009987 (0.62) ! cellular process; GO:0044699 (0.48) ! single-organism process; GO:0065007 (0.45) ! biological regulation; GO:0051179 (0.43) ! localization; GO:0051234 (0.42) ! establishment of localization; GO:0006810 (0.41) ! transport; GO:0051649 (0.39) ! establishment of localization in cell; GO:0051641 (0.39) ! cellular localization; GO:0050789 (0.39) ! regulation of biological process; GO:0050794 (0.37) ! regulation of cellular process; GO:0046907 (0.37) ! intracellular transport; GO:0044763 (0.36) ! single-organism cellular process; GO:0071702 (0.34) ! organic substance transport; GO:0051169 (0.33) ! nuclear transport; GO:0050658 (0.32) ! RNA transport; GO:0045184 (0.32) ! establishment of protein localization; GO:0032502 (0.26) ! developmental process; GO:0016043 (0.26) ! cellular component organization; GO:0044767 (0.25) ! single-organism developmental process; GO:0008152 (0.25) ! metabolic process; GO:0071704 (0.24) ! organic substance metabolic process; GO:0044238 (0.23) ! primary metabolic process; GO:0044237 (0.23) ! cellular metabolic process; GO:0043170 (0.22) ! macromolecule metabolic process; GO:0044260 (0.21) ! cellular macromolecule metabolic process; GO:0048856 (0.20) ! anatomical structure development; GO:0048523 (0.18) ! negative regulation of cellular process; GO:0048518 (0.18) ! positive regulation of biological process; GO:0032501 (0.18) ! multicellular organismal process; GO:0048522 (0.16) ! positive regulation of cellular process; GO:0006996 (0.16) ! organelle organization; GO:0065008 (0.15) ! regulation of biological quality; GO:0051128 (0.15) ! regulation of cellular component organization; GO:0044707 (0.15) ! single-multicellular organism process; GO:0019538 (0.15) ! protein metabolic process; GO:0019222 (0.15) ! regulation of metabolic process; GO:0080090 (0.14) ! regulation of primary metabolic process; GO:0060255 (0.14) ! regulation of macromolecule metabolic process; GO:0050896 (0.13) ! response to stimulus; GO:0048869 (0.13) ! cellular developmental process; GO:0044267 (0.13) ! cellular protein metabolic process; GO:0043412 (0.13) ! macromolecule modification; GO:0031323 (0.13) ! regulation of cellular metabolic process; GO:0009653 (0.12) ! anatomical structure morphogenesis; GO:0007165 (0.12) ! signal transduction; GO:0006464 (0.12) ! cellular protein modification process; GO:0007010 (0.11) ! cytoskeleton organization; GO:1902589 (0.10) ! single-organism organelle organization; GO:0051171 (0.10) ! regulation of nitrogen compound metabolic process; GO:0033043 (0.10) ! regulation of organelle organization; GO:0010468 (0.10) ! regulation of gene expression; GO:0006950 (0.10) ! response to stress; GO:2000112 (0.09) ! regulation of cellular macromolecule biosynthetic process; GO:0051239 (0.09) ! regulation of multicellular organismal process; GO:0050793 (0.09) ! regulation of developmental process; GO:0048513 (0.09) ! animal organ development; GO:0022402 (0.09) ! cell cycle process; GO:0019219 (0.09) ! regulation of nucleobase-containing compound metabolic process; GO:1903047 (0.08) ! mitotic cell cycle process; GO:0051252 (0.08) ! regulation of RNA metabolic process; GO:0051129 (0.08) ! negative regulation of cellular component organization; GO:0043933 (0.08) ! macromolecular complex subunit organization; GO:0032879 (0.08) ! regulation of localization; GO:0030036 (0.08) ! actin cytoskeleton organization; GO:0009892 (0.08) ! negative regulation of metabolic process; GO:0007017 (0.08) ! microtubule-based process; GO:0006807 (0.08) ! nitrogen compound metabolic process; GO:2000026 (0.07) ! regulation of multicellular organismal development; GO:0090304 (0.07) ! nucleic acid metabolic process; GO:0051130 (0.07) ! positive regulation of cellular component organization; GO:0048731 (0.07) ! system development; GO:0048646 (0.07) ! anatomical structure formation involved in morphogenesis; GO:0045595 (0.07) ! regulation of cell differentiation; GO:0031324 (0.07) ! negative regulation of cellular metabolic process; GO:0022603 (0.07) ! regulation of anatomical structure morphogenesis; GO:0022414 (0.07) ! reproductive process; GO:0010639 (0.07) ! negative regulation of organelle organization; GO:0010605 (0.07) ! negative regulation of macromolecule metabolic process; GO:0007267 (0.07) ! cell-cell signaling; GO:0006355 (0.07) ! regulation of transcription, DNA-templated; GO:1902578 (0.06) ! single-organism localization; GO:0065009 (0.06) ! regulation of molecular function; GO:0051726 (0.06) ! regulation of cell cycle; GO:0051716 (0.06) ! cellular response to stimulus; GO:0051246 (0.06) ! regulation of protein metabolic process; GO:0048583 (0.06) ! regulation of response to stimulus; GO:0045664 (0.06) ! regulation of neuron differentiation; GO:0044702 (0.06) ! single organism reproductive process; GO:0032989 (0.06) ! cellular component morphogenesis; GO:0031344 (0.06) ! regulation of cell projection organization; GO:0031325 (0.06) ! positive regulation of cellular metabolic process; GO:0030030 (0.06) ! cell projection organization; GO:0023051 (0.06) ! regulation of signaling; GO:0022607 (0.06) ! cellular component assembly; GO:0022604 (0.06) ! regulation of cell morphogenesis; GO:0010646 (0.06) ! regulation of cell communication; GO:0010604 (0.06) ! positive regulation of macromolecule metabolic process; GO:0009058 (0.06) ! biosynthetic process; GO:0008104 (0.06) ! protein localization; GO:0007475 (0.06) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.06) ! open tracheal system development; GO:0006928 (0.06) ! movement of cell or subcellular component; GO:0006796 (0.06) ! phosphate-containing compound metabolic process; GO:0006357 (0.06) ! regulation of transcription from RNA polymerase II promoter; GO:0000226 (0.06) ! microtubule cytoskeleton organization; GO:2000113 (0.05) ! negative regulation of cellular macromolecule biosynthetic process; GO:1901990 (0.05) ! regulation of mitotic cell cycle phase transition; GO:1901576 (0.05) ! organic substance biosynthetic process; GO:0070647 (0.05) ! protein modification by small protein conjugation or removal; GO:0051049 (0.05) ! regulation of transport; GO:0050770 (0.05) ! regulation of axonogenesis; GO:0050769 (0.05) ! positive regulation of neurogenesis; GO:0048858 (0.05) ! cell projection morphogenesis; GO:0045934 (0.05) ! negative regulation of nucleobase-containing compound metabolic process; GO:0045786 (0.05) ! negative regulation of cell cycle; GO:0044765 (0.05) ! single-organism transport; GO:0044710 (0.05) ! single-organism metabolic process; GO:0044249 (0.05) ! cellular biosynthetic process; GO:0044087 (0.05) ! regulation of cellular component biogenesis; GO:0040008 (0.05) ! regulation of growth; GO:0035556 (0.05) ! intracellular signal transduction; GO:0033044 (0.05) ! regulation of chromosome organization; GO:0032268 (0.05) ! regulation of cellular protein metabolic process; GO:0016192 (0.05) ! vesicle-mediated transport; GO:0016070 (0.05) ! RNA metabolic process; GO:0010629 (0.05) ! negative regulation of gene expression; GO:0009966 (0.05) ! regulation of signal transduction; GO:0007275 (0.05) ! multicellular organism development; GO:0006952 (0.05) ! defense response; GO:0006325 (0.05) ! chromatin organization; GO:0002376 (0.05) ! immune system process; GO:0071822 (0.04) ! protein complex subunit organization; GO:0070507 (0.04) ! regulation of microtubule cytoskeleton organization; GO:0050790 (0.04) ! regulation of catalytic activity; GO:0050772 (0.04) ! positive regulation of axonogenesis; GO:0048870 (0.04) ! cell motility; GO:0048812 (0.04) ! neuron projection morphogenesis; GO:0048638 (0.04) ! regulation of developmental growth; GO:0045893 (0.04) ! positive regulation of transcription, DNA-templated; GO:0044089 (0.04) ! positive regulation of cellular component biogenesis; GO:0042221 (0.04) ! response to chemical; GO:0034613 (0.04) ! cellular protein localization; GO:0033554 (0.04) ! cellular response to stress; GO:0030307 (0.04) ! positive regulation of cell growth; GO:0030154 (0.04) ! cell differentiation; GO:0022610 (0.04) ! biological adhesion; GO:0016567 (0.04) ! protein ubiquitination; GO:0016203 (0.04) ! muscle attachment; GO:0009888 (0.04) ! tissue development; GO:0009628 (0.04) ! response to abiotic stimulus; GO:0009605 (0.04) ! response to external stimulus; GO:0009059 (0.04) ! macromolecule biosynthetic process; GO:0008037 (0.04) ! cell recognition; GO:0007423 (0.04) ! sensory organ development; GO:0007166 (0.04) ! cell surface receptor signaling pathway; GO:0007094 (0.04) ! mitotic spindle assembly checkpoint; GO:0007015 (0.04) ! actin filament organization; GO:0006913 (0.04) ! nucleocytoplasmic transport; GO:0006468 (0.04) ! protein phosphorylation; GO:0003008 (0.04) ! system process; GO:0000122 (0.04) ! negative regulation of transcription from RNA polymerase II promoter; GO:1902580 (0.03) ! single-organism cellular localization; GO:1902531 (0.03) ! regulation of intracellular signal transduction; GO:1901575 (0.03) ! organic substance catabolic process; GO:0070887 (0.03) ! cellular response to chemical stimulus; GO:0061061 (0.03) ! muscle structure development; GO:0051704 (0.03) ! multi-organism process; GO:0051656 (0.03) ! establishment of organelle localization; GO:0051491 (0.03) ! positive regulation of filopodium assembly; GO:0051050 (0.03) ! positive regulation of transport; GO:0048813 (0.03) ! dendrite morphogenesis; GO:0048589 (0.03) ! developmental growth; GO:0048468 (0.03) ! cell development; GO:0046331 (0.03) ! lateral inhibition; GO:0045944 (0.03) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045773 (0.03) ! positive regulation of axon extension; GO:0045087 (0.03) ! innate immune response; GO:0044723 (0.03) ! single-organism carbohydrate metabolic process; GO:0044719 (0.03) ! regulation of imaginal disc-derived wing size; GO:0044093 (0.03) ! positive regulation of molecular function; GO:0042787 (0.03) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0042592 (0.03) ! homeostatic process; GO:0040005 (0.03) ! chitin-based cuticle attachment to epithelium; GO:0035149 (0.03) ! lumen formation, open tracheal system; GO:0035147 (0.03) ! branch fusion, open tracheal system; GO:0034645 (0.03) ! cellular macromolecule biosynthetic process; GO:0034622 (0.03) ! cellular macromolecular complex assembly; GO:0033365 (0.03) ! protein localization to organelle; GO:0032774 (0.03) ! RNA biosynthetic process; GO:0032269 (0.03) ! negative regulation of cellular protein metabolic process; GO:0031032 (0.03) ! actomyosin structure organization; GO:0030716 (0.03) ! oocyte fate determination; GO:0030155 (0.03) ! regulation of cell adhesion; GO:0022412 (0.03) ! cellular process involved in reproduction in multicellular organism; GO:0016477 (0.03) ! cell migration; GO:0016319 (0.03) ! mushroom body development; GO:0016204 (0.03) ! determination of muscle attachment site; GO:0016199 (0.03) ! axon midline choice point recognition; GO:0010033 (0.03) ! response to organic substance; GO:0009968 (0.03) ! negative regulation of signal transduction; GO:0009967 (0.03) ! positive regulation of signal transduction; GO:0008362 (0.03) ! chitin-based embryonic cuticle biosynthetic process; GO:0007409 (0.03) ! axonogenesis; GO:0007155 (0.03) ! cell adhesion; GO:0007026 (0.03) ! negative regulation of microtubule depolymerization; GO:0006886 (0.03) ! intracellular protein transport; GO:0006461 (0.03) ! protein complex assembly; GO:0001932 (0.03) ! regulation of protein phosphorylation; GO:0001578 (0.03) ! microtubule bundle formation; GO:2000021 (0.02) ! regulation of ion homeostasis; GO:1902582 (0.02) ! single-organism intracellular transport; GO:1902275 (0.02) ! regulation of chromatin organization; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:0098542 (0.02) ! defense response to other organism; GO:0080134 (0.02) ! regulation of response to stress; GO:0071310 (0.02) ! cellular response to organic substance; GO:0070925 (0.02) ! organelle assembly; GO:0061024 (0.02) ! membrane organization; GO:0060627 (0.02) ! regulation of vesicle-mediated transport; GO:0050776 (0.02) ! regulation of immune response; GO:0048729 (0.02) ! tissue morphogenesis; GO:0048675 (0.02) ! axon extension; GO:0045859 (0.02) ! regulation of protein kinase activity; GO:0045214 (0.02) ! sarcomere organization; GO:0044711 (0.02) ! single-organism biosynthetic process; GO:0044265 (0.02) ! cellular macromolecule catabolic process; GO:0044092 (0.02) ! negative regulation of molecular function; GO:0043623 (0.02) ! cellular protein complex assembly; GO:0043087 (0.02) ! regulation of GTPase activity; GO:0043085 (0.02) ! positive regulation of catalytic activity; GO:0043009 (0.02) ! chordate embryonic development; GO:0042127 (0.02) ! regulation of cell proliferation; GO:0040023 (0.02) ! establishment of nucleus localization; GO:0032412 (0.02) ! regulation of ion transmembrane transporter activity; GO:0032386 (0.02) ! regulation of intracellular transport; GO:0032270 (0.02) ! positive regulation of cellular protein metabolic process; GO:0031400 (0.02) ! negative regulation of protein modification process; GO:0030518 (0.02) ! intracellular steroid hormone receptor signaling pathway; GO:0030334 (0.02) ! regulation of cell migration; GO:0022411 (0.02) ! cellular component disassembly; GO:0016570 (0.02) ! histone modification; GO:0016482 (0.02) ! cytosolic transport; GO:0016337 (0.02) ! single organismal cell-cell adhesion; GO:0016266 (0.02) ! O-glycan processing; GO:0016071 (0.02) ! mRNA metabolic process; GO:0010941 (0.02) ! regulation of cell death; GO:0010927 (0.02) ! cellular component assembly involved in morphogenesis; GO:0010638 (0.02) ! positive regulation of organelle organization; GO:0008283 (0.02) ! cell proliferation; GO:0007600 (0.02) ! sensory perception; GO:0007523 (0.02) ! larval visceral muscle development; GO:0007519 (0.02) ! skeletal muscle tissue development; GO:0007420 (0.02) ! brain development; GO:0007018 (0.02) ! microtubule-based movement; GO:0006997 (0.02) ! nucleus organization; GO:0006897 (0.02) ! endocytosis; GO:0006888 (0.02) ! ER to Golgi vesicle-mediated transport; GO:0006874 (0.02) ! cellular calcium ion homeostasis; GO:0006812 (0.02) ! cation transport; GO:0006508 (0.02) ! proteolysis; GO:0006417 (0.02) ! regulation of translation; GO:0006351 (0.02) ! transcription, DNA-templated; GO:0006338 (0.02) ! chromatin remodeling; GO:0006281 (0.02) ! DNA repair; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0003002 (0.02) ! regionalization; GO:0002684 (0.02) ! positive regulation of immune system process; GO:0000902 (0.02) ! cell morphogenesis; GO:2000651 (0.01) ! positive regulation of sodium ion transmembrane transporter activity; GO:1903046 (0.01) ! meiotic cell cycle process; GO:1902533 (0.01) ! positive regulation of intracellular signal transduction; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1902287 (0.01) ! semaphorin-plexin signaling pathway involved in axon guidance; GO:1901673 (0.01) ! regulation of mitotic spindle assembly; GO:1901564 (0.01) ! organonitrogen compound metabolic process; GO:1901136 (0.01) ! carbohydrate derivative catabolic process; GO:1900087 (0.01) ! positive regulation of G1/S transition of mitotic cell cycle; GO:0099531 (0.01) ! presynaptic process involved in chemical synaptic transmission; GO:0098901 (0.01) ! regulation of cardiac muscle cell action potential; GO:0097193 (0.01) ! intrinsic apoptotic signaling pathway; GO:0090630 (0.01) ! activation of GTPase activity; GO:0090287 (0.01) ! regulation of cellular response to growth factor stimulus; GO:0090267 (0.01) ! positive regulation of mitotic cell cycle spindle assembly checkpoint; GO:0090257 (0.01) ! regulation of muscle system process; GO:0090239 (0.01) ! regulation of histone H4 acetylation; GO:0090114 (0.01) ! COPII-coated vesicle budding; GO:0090090 (0.01) ! negative regulation of canonical Wnt signaling pathway; GO:0086010 (0.01) ! membrane depolarization during action potential; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0072661 (0.01) ! protein targeting to plasma membrane; GO:0072331 (0.01) ! signal transduction by p53 class mediator; GO:0071495 (0.01) ! cellular response to endogenous stimulus; GO:0071478 (0.01) ! cellular response to radiation; GO:0071470 (0.01) ! cellular response to osmotic stress; GO:0071363 (0.01) ! cellular response to growth factor stimulus; GO:0071345 (0.01) ! cellular response to cytokine stimulus; GO:0071300 (0.01) ! cellular response to retinoic acid; GO:0071241 (0.01) ! cellular response to inorganic substance; GO:0070849 (0.01) ! response to epidermal growth factor; GO:0061077 (0.01) ! chaperone-mediated protein folding; GO:0060429 (0.01) ! epithelium development; GO:0060361 (0.01) ! flight; GO:0060271 (0.01) ! cilium morphogenesis; GO:0060070 (0.01) ! canonical Wnt signaling pathway; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0060026 (0.01) ! convergent extension; GO:0055114 (0.01) ! oxidation-reduction process; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051646 (0.01) ! mitochondrion localization; GO:0051643 (0.01) ! endoplasmic reticulum localization; GO:0051607 (0.01) ! defense response to virus; GO:0051592 (0.01) ! response to calcium ion; GO:0051315 (0.01) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051292 (0.01) ! nuclear pore complex assembly; GO:0051276 (0.01) ! chromosome organization; GO:0051272 (0.01) ! positive regulation of cellular component movement; GO:0051225 (0.01) ! spindle assembly; GO:0051209 (0.01) ! release of sequestered calcium ion into cytosol; GO:0051056 (0.01) ! regulation of small GTPase mediated signal transduction; GO:0050982 (0.01) ! detection of mechanical stimulus; GO:0050878 (0.01) ! regulation of body fluid levels; GO:0050857 (0.01) ! positive regulation of antigen receptor-mediated signaling pathway; GO:0050853 (0.01) ! B cell receptor signaling pathway; GO:0050852 (0.01) ! T cell receptor signaling pathway; GO:0050829 (0.01) ! defense response to Gram-negative bacterium; GO:0050684 (0.01) ! regulation of mRNA processing; GO:0048846 (0.01) ! axon extension involved in axon guidance; GO:0048739 (0.01) ! cardiac muscle fiber development; GO:0048666 (0.01) ! neuron development; GO:0048598 (0.01) ! embryonic morphogenesis; GO:0048534 (0.01) ! hematopoietic or lymphoid organ development; GO:0048524 (0.01) ! positive regulation of viral process; GO:0048514 (0.01) ! blood vessel morphogenesis; GO:0048489 (0.01) ! synaptic vesicle transport; GO:0048488 (0.01) ! synaptic vesicle endocytosis; GO:0046832 (0.01) ! negative regulation of RNA export from nucleus; GO:0046827 (0.01) ! positive regulation of protein export from nucleus; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046488 (0.01) ! phosphatidylinositol metabolic process; GO:0046425 (0.01) ! regulation of JAK-STAT cascade; GO:0045947 (0.01) ! negative regulation of translational initiation; GO:0045665 (0.01) ! negative regulation of neuron differentiation; GO:0045089 (0.01) ! positive regulation of innate immune response; GO:0044772 (0.01) ! mitotic cell cycle phase transition; GO:0044712 (0.01) ! single-organism catabolic process; GO:0044708 (0.01) ! single-organism behavior; GO:0043578 (0.01) ! nuclear matrix organization; GO:0043484 (0.01) ! regulation of RNA splicing; GO:0043414 (0.01) ! macromolecule methylation; GO:0043408 (0.01) ! regulation of MAPK cascade; GO:0043254 (0.01) ! regulation of protein complex assembly; GO:0043122 (0.01) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0043044 (0.01) ! ATP-dependent chromatin remodeling; GO:0042307 (0.01) ! positive regulation of protein import into nucleus; GO:0042102 (0.01) ! positive regulation of T cell proliferation; GO:0042100 (0.01) ! B cell proliferation; GO:0040029 (0.01) ! regulation of gene expression, epigenetic; GO:0035385 (0.01) ! Roundabout signaling pathway; GO:0035372 (0.01) ! protein localization to microtubule; GO:0035295 (0.01) ! tube development; GO:0035264 (0.01) ! multicellular organism growth; GO:0034660 (0.01) ! ncRNA metabolic process; GO:0034599 (0.01) ! cellular response to oxidative stress; GO:0034501 (0.01) ! protein localization to kinetochore; GO:0034453 (0.01) ! microtubule anchoring; GO:0033227 (0.01) ! dsRNA transport; GO:0032970 (0.01) ! regulation of actin filament-based process; GO:0032958 (0.01) ! inositol phosphate biosynthetic process; GO:0032786 (0.01) ! positive regulation of DNA-templated transcription, elongation; GO:0032535 (0.01) ! regulation of cellular component size; GO:0032530 (0.01) ! regulation of microvillus organization; GO:0032197 (0.01) ! transposition, RNA-mediated; GO:0032101 (0.01) ! regulation of response to external stimulus; GO:0031990 (0.01) ! mRNA export from nucleus in response to heat stress; GO:0031647 (0.01) ! regulation of protein stability; GO:0031505 (0.01) ! fungal-type cell wall organization; GO:0031453 (0.01) ! positive regulation of heterochromatin assembly; GO:0031338 (0.01) ! regulation of vesicle fusion; GO:0031134 (0.01) ! sister chromatid biorientation; GO:0031060 (0.01) ! regulation of histone methylation; GO:0030866 (0.01) ! cortical actin cytoskeleton organization; GO:0030705 (0.01) ! cytoskeleton-dependent intracellular transport; GO:0030241 (0.01) ! skeletal muscle myosin thick filament assembly; GO:0030240 (0.01) ! skeletal muscle thin filament assembly; GO:0030217 (0.01) ! T cell differentiation; GO:0030198 (0.01) ! extracellular matrix organization; GO:0030182 (0.01) ! neuron differentiation; GO:0030163 (0.01) ! protein catabolic process; GO:0030100 (0.01) ! regulation of endocytosis; GO:0030042 (0.01) ! actin filament depolymerization; GO:0022600 (0.01) ! digestive system process; GO:0022008 (0.01) ! neurogenesis; GO:0019827 (0.01) ! stem cell population maintenance; GO:0019233 (0.01) ! sensory perception of pain; GO:0018205 (0.01) ! peptidyl-lysine modification; GO:0017157 (0.01) ! regulation of exocytosis; GO:0016575 (0.01) ! histone deacetylation; GO:0016458 (0.01) ! gene silencing; GO:0016236 (0.01) ! macroautophagy; GO:0016197 (0.01) ! endosomal transport; GO:0016191 (0.01) ! synaptic vesicle uncoating; GO:0010793 (0.01) ! regulation of mRNA export from nucleus; GO:0009887 (0.01) ! organ morphogenesis; GO:0009411 (0.01) ! response to UV; GO:0008610 (0.01) ! lipid biosynthetic process; GO:0008360 (0.01) ! regulation of cell shape; GO:0008335 (0.01) ! female germline ring canal stabilization; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008045 (0.01) ! motor neuron axon guidance; GO:0007626 (0.01) ! locomotory behavior; GO:0007605 (0.01) ! sensory perception of sound; GO:0007525 (0.01) ! somatic muscle development; GO:0007498 (0.01) ! mesoderm development; GO:0007492 (0.01) ! endoderm development; GO:0007417 (0.01) ! central nervous system development; GO:0007416 (0.01) ! synapse assembly; GO:0007339 (0.01) ! binding of sperm to zona pellucida; GO:0007303 (0.01) ! cytoplasmic transport, nurse cell to oocyte; GO:0007298 (0.01) ! border follicle cell migration; GO:0007283 (0.01) ! spermatogenesis; GO:0007268 (0.01) ! chemical synaptic transmission; GO:0007219 (0.01) ! Notch signaling pathway; GO:0007186 (0.01) ! G-protein coupled receptor signaling pathway; GO:0007162 (0.01) ! negative regulation of cell adhesion; GO:0007052 (0.01) ! mitotic spindle organization; GO:0007033 (0.01) ! vacuole organization; GO:0007005 (0.01) ! mitochondrion organization; GO:0006941 (0.01) ! striated muscle contraction; GO:0006892 (0.01) ! post-Golgi vesicle-mediated transport; GO:0006887 (0.01) ! exocytosis; GO:0006611 (0.01) ! protein export from nucleus; GO:0006511 (0.01) ! ubiquitin-dependent protein catabolic process; GO:0006470 (0.01) ! protein dephosphorylation; GO:0006469 (0.01) ! negative regulation of protein kinase activity; GO:0006404 (0.01) ! RNA import into nucleus; GO:0006368 (0.01) ! transcription elongation from RNA polymerase II promoter; GO:0006367 (0.01) ! transcription initiation from RNA polymerase II promoter; GO:0006366 (0.01) ! transcription from RNA polymerase II promoter; GO:0006334 (0.01) ! nucleosome assembly; GO:0006310 (0.01) ! DNA recombination; GO:0006302 (0.01) ! double-strand break repair; GO:0006020 (0.01) ! inositol metabolic process; GO:0002064 (0.01) ! epithelial cell development; GO:0001960 (0.01) ! negative regulation of cytokine-mediated signaling pathway; GO:0001934 (0.01) ! positive regulation of protein phosphorylation; GO:0001915 (0.01) ! negative regulation of T cell mediated cytotoxicity; GO:0001894 (0.01) ! tissue homeostasis; GO:0001892 (0.01) ! embryonic placenta development; GO:0001817 (0.01) ! regulation of cytokine production; GO:0001756 (0.01) ! somitogenesis; GO:0001701 (0.01) ! in utero embryonic development; GO:0001654 (0.01) ! eye development; GO:0001501 (0.01) ! skeletal system development; GO:0000398 (0.01) ! mRNA splicing, via spliceosome; GO:0000288 (0.01) ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; GO:0000281 (0.01) ! mitotic cytokinesis; GO:0000280 (0.01) ! nuclear division; GO:0000189 (0.01) ! MAPK import into nucleus; GO:0000132 (0.01) ! establishment of mitotic spindle orientation; GO:0000077 (0.01) ! DNA damage checkpoint; GO:0000018 (0.01) ! regulation of DNA recombination GO:0005887 (1.00) ! integral component of plasma membrane Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells. {ECO:0000269|PubMed:28186500}. GO:2000035 ! regulation of stem cell division; GO:0030854 ! positive regulation of granulocyte differentiation; GO:0061515 ! myeloid cell development; GO:0005887 ! integral component of plasma membrane; GO:0043066 ! negative regulation of apoptotic process; GO:0071157 ! negative regulation of cell cycle arrest; GO:0045660 ! positive regulation of neutrophil differentiation GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 5 GO:0030854 ! positive regulation of granulocyte differentiation; GO:0043066 ! negative regulation of apoptotic process; GO:0045660 ! positive regulation of neutrophil differentiation; GO:0061515 ! myeloid cell development; GO:0071157 ! negative regulation of cell cycle arrest; GO:2000035 ! regulation of stem cell division 31303766-31314112 (17q11.2) High: cerebellum (cells in molecular layer; Purkinje cells);lymph node (germinal center cells; non-germinal center cells);hippocampus (neuronal cells);caudate (neuronal cells);spleen (cells in red pulp; cells in white pulp);bone marrow (hematopoietic cells);tonsil (germinal center cells; non-germinal center cells);salivary gland (glandular cells);appendix (lymphoid tissue);colon (peripheral nerve/ganglion);lung (macrophages);cerebral cortex (neuronal cells);Medium: stomach 2 (glandular cells);small intestine (glandular cells);stomach 1 (glandular cells);liver (hepatocytes);bronchus (respiratory epithelial cells);testis (cells in seminiferous ducts);epididymis (glandular cells);endometrium 1 (glandular cells);endometrium 2 (glandular cells);appendix (glandular cells);colon (glandular cells);breast (glandular cells; myoepithelial cells);seminal vesicle (glandular cells);rectum (glandular cells);pancreas (exocrine glandular cells);skin 1 (Langerhans);kidney (cells in tubules);duodenum (glandular cells);Low: placenta (trophoblastic cells);caudate (glial cells);fallopian tube (glandular cells);skin 1 (keratinocytes);tonsil (squamous epithelial cells);skeletal muscle (myocytes);urinary bladder (urothelial cells);adrenal gland (glandular cells);thyroid gland (glandular cells);colon (endothelial cells);gallbladder (glandular cells);lung (pneumocytes);ovary (ovarian stroma cells);prostate (glandular cells);cervix, uterine (glandular cells);heart muscle (myocytes); Whole Blood: 618.20; Spleen: 186.30; Cells - EBV-transformed lymphocytes: 162.50; Lung: 65.21; Small Intestine - Terminal Ileum: 30.21; Cells - Transformed fibroblasts: 25.41; Brain - Spinal cord (cervical c-1): 19.71; Adipose - Visceral (Omentum): 18.33; Adipose - Subcutaneous: 15.60; Colon - Transverse: 13.51; Minor Salivary Gland: 13.36; Artery - Coronary: 13.18; Bladder: 12.37; Artery - Aorta: 10.57; Nerve - Tibial: 9.02; Cervix - Endocervix: 8.99; Breast - Mammary Tissue: 8.41; Brain - Substantia nigra: 8.33; Fallopian Tube: 7.94; Prostate: 7.57; Stomach: 7.00; Vagina: 6.57; Thyroid: 6.39; Colon - Sigmoid: 6.14; Adrenal Gland: 5.75; Artery - Tibial: 5.56; Uterus: 5.52; Esophagus - Muscularis: 5.44; Esophagus - Gastroesophageal Junction: 5.38; Brain - Hippocampus: 5.26; Cervix - Ectocervix: 5.15; Brain - Hypothalamus: 5.05; Esophagus - Mucosa: 4.86; Brain - Amygdala: 3.90; Skin - Sun Exposed (Lower leg): 3.75; Brain - Caudate (basal ganglia): 3.66; Skin - Not Sun Exposed (Suprapubic): 3.44; Brain - Putamen (basal ganglia): 3.39; Liver: 3.35; Heart - Atrial Appendage: 3.14; Brain - Nucleus accumbens (basal ganglia): 2.77; Kidney - Cortex: 2.70; Ovary: 2.58; Pituitary: 2.47; Testis: 2.44; Brain - Frontal Cortex (BA9): 2.37; Brain - Cortex: 2.06; Brain - Anterior cingulate cortex (BA24): 1.94; Heart - Left Ventricle: 1.46; Brain - Cerebellar Hemisphere: 1.42; Pancreas: 1.29; Brain - Cerebellum: 1.12; Muscle - Skeletal: 0.85; MDPKYFILILFCGHLNNTFFSKTETITTEKQSQPTLFTSSMSQVLANSQNTTGNPLGQPTQFSDTFSGQSISPAKVTAGQPTPAVYTSSEKPEAHTSAGQPLAYNTKQPTPIANTSSQQAVFTSARQLPSARTSTTQPPKSFVYTFTQQSSSVQIPSRKQITVHNPSTQPTSTVKNSPRSTPGFILDTTSNKQTPQKNNYNSIAAILIGVLLTSMLVAIIIIVLWKCLRKPVLNDQNWAGRSPFADGETPDICMDNIRENEISTKRTSIISLTPWKPSKSTLLADDLEIKLFESSENIEDSNNPKTEKIKDQVNGTSEDSADGSTVGTAVSSSDDADLPPPPPLLDLEGQESNQSDKPTMTIVSPLPNDSTSLPPSLDCLNQDCGDHKSEIIQSFPPLDSLNLPLPPVDFMKNQEDSNLEIQCQEFSIPPNSDQDLNESLPPPPAELL LRRC37B Leucine-rich repeat-containing protein 37B LR37B_HUMAN (Q96QE4-1) GO:0005215 (0.35) ! transporter activity; GO:0022892 (0.34) ! substrate-specific transporter activity; GO:0098772 (0.28) ! molecular function regulator; GO:0004857 (0.27) ! enzyme inhibitor activity; GO:0004860 (0.26) ! protein kinase inhibitor activity; GO:0005102 (0.16) ! receptor binding; GO:0097367 (0.15) ! carbohydrate derivative binding; GO:0004872 (0.15) ! receptor activity; GO:0005539 (0.14) ! glycosaminoglycan binding; GO:0008201 (0.13) ! heparin binding; GO:0048495 (0.12) ! Roundabout binding; GO:0004871 (0.12) ! signal transducer activity; GO:0003824 (0.12) ! catalytic activity; GO:1901363 (0.11) ! heterocyclic compound binding; GO:0097159 (0.11) ! organic cyclic compound binding; GO:0038023 (0.11) ! signaling receptor activity; GO:0003676 (0.10) ! nucleic acid binding; GO:0004888 (0.09) ! transmembrane signaling receptor activity; GO:0003723 (0.08) ! RNA binding; GO:0016740 (0.06) ! transferase activity; GO:0004930 (0.06) ! G-protein coupled receptor activity; GO:0004672 (0.05) ! protein kinase activity; GO:0044877 (0.04) ! macromolecular complex binding; GO:0016787 (0.04) ! hydrolase activity; GO:0005198 (0.04) ! structural molecule activity; GO:0004674 (0.04) ! protein serine/threonine kinase activity; GO:0044822 (0.03) ! poly(A) RNA binding; GO:0032403 (0.03) ! protein complex binding; GO:0019899 (0.03) ! enzyme binding; GO:0008092 (0.03) ! cytoskeletal protein binding; GO:0003725 (0.03) ! double-stranded RNA binding; GO:0001653 (0.03) ! peptide receptor activity; GO:0070851 (0.02) ! growth factor receptor binding; GO:0042802 (0.02) ! identical protein binding; GO:0019838 (0.02) ! growth factor binding; GO:0008528 (0.02) ! G-protein coupled peptide receptor activity; GO:0008289 (0.02) ! lipid binding; GO:0005518 (0.02) ! collagen binding; GO:0005201 (0.02) ! extracellular matrix structural constituent; GO:0003779 (0.02) ! actin binding; GO:0003700 (0.02) ! transcription factor activity, sequence-specific DNA binding; GO:0003682 (0.02) ! chromatin binding; GO:0003677 (0.02) ! DNA binding; GO:0097493 (0.01) ! structural molecule activity conferring elasticity; GO:0071723 (0.01) ! lipopeptide binding; GO:0070052 (0.01) ! collagen V binding; GO:0070011 (0.01) ! peptidase activity, acting on L-amino acid peptides; GO:0051371 (0.01) ! muscle alpha-actinin binding; GO:0051015 (0.01) ! actin filament binding; GO:0050840 (0.01) ! extracellular matrix binding; GO:0050431 (0.01) ! transforming growth factor beta binding; GO:0046873 (0.01) ! metal ion transmembrane transporter activity; GO:0045502 (0.01) ! dynein binding; GO:0042803 (0.01) ! protein homodimerization activity; GO:0042393 (0.01) ! histone binding; GO:0030695 (0.01) ! GTPase regulator activity; GO:0019902 (0.01) ! phosphatase binding; GO:0019901 (0.01) ! protein kinase binding; GO:0017016 (0.01) ! Ras GTPase binding; GO:0016791 (0.01) ! phosphatase activity; GO:0016779 (0.01) ! nucleotidyltransferase activity; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008190 (0.01) ! eukaryotic initiation factor 4E binding; GO:0008134 (0.01) ! transcription factor binding; GO:0008094 (0.01) ! DNA-dependent ATPase activity; GO:0008017 (0.01) ! microtubule binding; GO:0005543 (0.01) ! phospholipid binding; GO:0005520 (0.01) ! insulin-like growth factor binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005487 (0.01) ! nucleocytoplasmic transporter activity; GO:0005261 (0.01) ! cation channel activity; GO:0005154 (0.01) ! epidermal growth factor receptor binding; GO:0005126 (0.01) ! cytokine receptor binding; GO:0005048 (0.01) ! signal sequence binding; GO:0005030 (0.01) ! neurotrophin receptor activity; GO:0004963 (0.01) ! follicle-stimulating hormone receptor activity; GO:0004842 (0.01) ! ubiquitin-protein transferase activity; GO:0004826 (0.01) ! phenylalanine-tRNA ligase activity; GO:0004713 (0.01) ! protein tyrosine kinase activity; GO:0004702 (0.01) ! receptor signaling protein serine/threonine kinase activity; GO:0004061 (0.01) ! arylformamidase activity; GO:0003727 (0.01) ! single-stranded RNA binding; GO:0003713 (0.01) ! transcription coactivator activity; GO:0001875 (0.01) ! lipopolysaccharide receptor activity; GO:0001530 (0.01) ! lipopolysaccharide binding; GO:0001191 (0.01) ! transcriptional repressor activity, RNA polymerase II transcription factor binding; GO:0001104 (0.01) ! RNA polymerase II transcription cofactor activity; GO:0000981 (0.01) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0000976 (0.01) ! transcription regulatory region sequence-specific DNA binding; GO:0000166 (0.01) ! nucleotide binding GO:0065007 (0.62) ! biological regulation; GO:0050789 (0.61) ! regulation of biological process; GO:0009987 (0.60) ! cellular process; GO:0050794 (0.59) ! regulation of cellular process; GO:0044699 (0.53) ! single-organism process; GO:0044763 (0.48) ! single-organism cellular process; GO:0007165 (0.45) ! signal transduction; GO:0032502 (0.42) ! developmental process; GO:0044767 (0.41) ! single-organism developmental process; GO:0051179 (0.35) ! localization; GO:0016043 (0.35) ! cellular component organization; GO:0051641 (0.34) ! cellular localization; GO:0006810 (0.34) ! transport; GO:0051649 (0.33) ! establishment of localization in cell; GO:0008104 (0.33) ! protein localization; GO:0048583 (0.32) ! regulation of response to stimulus; GO:0006886 (0.32) ! intracellular protein transport; GO:0007166 (0.31) ! cell surface receptor signaling pathway; GO:0031323 (0.30) ! regulation of cellular metabolic process; GO:0080090 (0.29) ! regulation of primary metabolic process; GO:0009653 (0.29) ! anatomical structure morphogenesis; GO:0060255 (0.28) ! regulation of macromolecule metabolic process; GO:0048869 (0.28) ! cellular developmental process; GO:0048523 (0.28) ! negative regulation of cellular process; GO:0065009 (0.25) ! regulation of molecular function; GO:0030030 (0.25) ! cell projection organization; GO:0009966 (0.25) ! regulation of signal transduction; GO:0048858 (0.24) ! cell projection morphogenesis; GO:0019220 (0.24) ! regulation of phosphate metabolic process; GO:0051246 (0.23) ! regulation of protein metabolic process; GO:0050790 (0.23) ! regulation of catalytic activity; GO:0031324 (0.23) ! negative regulation of cellular metabolic process; GO:0010605 (0.23) ! negative regulation of macromolecule metabolic process; GO:0007409 (0.23) ! axonogenesis; GO:1902531 (0.22) ! regulation of intracellular signal transduction; GO:0042325 (0.22) ! regulation of phosphorylation; GO:0031399 (0.22) ! regulation of protein modification process; GO:0009968 (0.22) ! negative regulation of signal transduction; GO:0045936 (0.21) ! negative regulation of phosphate metabolic process; GO:0032269 (0.21) ! negative regulation of cellular protein metabolic process; GO:0001932 (0.21) ! regulation of protein phosphorylation; GO:0046426 (0.20) ! negative regulation of JAK-STAT cascade; GO:0019221 (0.20) ! cytokine-mediated signaling pathway; GO:0006469 (0.20) ! negative regulation of protein kinase activity; GO:0048518 (0.19) ! positive regulation of biological process; GO:0051239 (0.16) ! regulation of multicellular organismal process; GO:0051128 (0.15) ! regulation of cellular component organization; GO:0050896 (0.14) ! response to stimulus; GO:0050793 (0.14) ! regulation of developmental process; GO:2000026 (0.13) ! regulation of multicellular organismal development; GO:0051960 (0.12) ! regulation of nervous system development; GO:0045595 (0.12) ! regulation of cell differentiation; GO:0060284 (0.11) ! regulation of cell development; GO:0048522 (0.11) ! positive regulation of cellular process; GO:0022603 (0.11) ! regulation of anatomical structure morphogenesis; GO:0071704 (0.10) ! organic substance metabolic process; GO:0050770 (0.10) ! regulation of axonogenesis; GO:0048856 (0.10) ! anatomical structure development; GO:0048589 (0.10) ! developmental growth; GO:0048584 (0.10) ! positive regulation of response to stimulus; GO:0044237 (0.10) ! cellular metabolic process; GO:0006950 (0.10) ! response to stress; GO:0002376 (0.10) ! immune system process; GO:0048846 (0.09) ! axon extension involved in axon guidance; GO:0044238 (0.09) ! primary metabolic process; GO:0043170 (0.09) ! macromolecule metabolic process; GO:0035385 (0.09) ! Roundabout signaling pathway; GO:0002682 (0.09) ! regulation of immune system process; GO:0050776 (0.08) ! regulation of immune response; GO:0044260 (0.08) ! cellular macromolecule metabolic process; GO:0032501 (0.08) ! multicellular organismal process; GO:0031347 (0.08) ! regulation of defense response; GO:0009605 (0.08) ! response to external stimulus; GO:0006952 (0.08) ! defense response; GO:0002684 (0.08) ! positive regulation of immune system process; GO:0051704 (0.07) ! multi-organism process; GO:0045089 (0.07) ! positive regulation of innate immune response; GO:0043207 (0.07) ! response to external biotic stimulus; GO:0031326 (0.07) ! regulation of cellular biosynthetic process; GO:0019219 (0.07) ! regulation of nucleobase-containing compound metabolic process; GO:0002253 (0.07) ! activation of immune response; GO:0098542 (0.06) ! defense response to other organism; GO:0031325 (0.06) ! positive regulation of cellular metabolic process; GO:0010556 (0.06) ! regulation of macromolecule biosynthetic process; GO:0006928 (0.06) ! movement of cell or subcellular component; GO:0002224 (0.06) ! toll-like receptor signaling pathway; GO:2000112 (0.05) ! regulation of cellular macromolecule biosynthetic process; GO:0065008 (0.05) ! regulation of biological quality; GO:0051252 (0.05) ! regulation of RNA metabolic process; GO:0044707 (0.05) ! single-multicellular organism process; GO:0044267 (0.05) ! cellular protein metabolic process; GO:0032879 (0.05) ! regulation of localization; GO:0031328 (0.05) ! positive regulation of cellular biosynthetic process; GO:0022607 (0.05) ! cellular component assembly; GO:0010468 (0.05) ! regulation of gene expression; GO:0006996 (0.05) ! organelle organization; GO:0006807 (0.05) ! nitrogen compound metabolic process; GO:0090304 (0.04) ! nucleic acid metabolic process; GO:0051716 (0.04) ! cellular response to stimulus; GO:0051240 (0.04) ! positive regulation of multicellular organismal process; GO:0051049 (0.04) ! regulation of transport; GO:0048513 (0.04) ! animal organ development; GO:0045935 (0.04) ! positive regulation of nucleobase-containing compound metabolic process; GO:0044702 (0.04) ! single organism reproductive process; GO:0044093 (0.04) ! positive regulation of molecular function; GO:0044087 (0.04) ! regulation of cellular component biogenesis; GO:0043933 (0.04) ! macromolecular complex subunit organization; GO:0010604 (0.04) ! positive regulation of macromolecule metabolic process; GO:0010033 (0.04) ! response to organic substance; GO:0007411 (0.04) ! axon guidance; GO:0007188 (0.04) ! adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0006464 (0.04) ! cellular protein modification process; GO:0006355 (0.04) ! regulation of transcription, DNA-templated; GO:0003008 (0.04) ! system process; GO:1902589 (0.03) ! single-organism organelle organization; GO:1902578 (0.03) ! single-organism localization; GO:0065003 (0.03) ! macromolecular complex assembly; GO:0051241 (0.03) ! negative regulation of multicellular organismal process; GO:0051130 (0.03) ! positive regulation of cellular component organization; GO:0051094 (0.03) ! positive regulation of developmental process; GO:0045937 (0.03) ! positive regulation of phosphate metabolic process; GO:0040008 (0.03) ! regulation of growth; GO:0035556 (0.03) ! intracellular signal transduction; GO:0033043 (0.03) ! regulation of organelle organization; GO:0016477 (0.03) ! cell migration; GO:0016070 (0.03) ! RNA metabolic process; GO:0010629 (0.03) ! negative regulation of gene expression; GO:0010557 (0.03) ! positive regulation of macromolecule biosynthetic process; GO:0009967 (0.03) ! positive regulation of signal transduction; GO:0009617 (0.03) ! response to bacterium; GO:0007155 (0.03) ! cell adhesion; GO:0007010 (0.03) ! cytoskeleton organization; GO:0006955 (0.03) ! immune response; GO:0006954 (0.03) ! inflammatory response; GO:0006468 (0.03) ! protein phosphorylation; GO:0006357 (0.03) ! regulation of transcription from RNA polymerase II promoter; GO:0003006 (0.03) ! developmental process involved in reproduction; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:0071822 (0.02) ! protein complex subunit organization; GO:0070925 (0.02) ! organelle assembly; GO:0070887 (0.02) ! cellular response to chemical stimulus; GO:0051962 (0.02) ! positive regulation of nervous system development; GO:0051607 (0.02) ! defense response to virus; GO:0051270 (0.02) ! regulation of cellular component movement; GO:0051247 (0.02) ! positive regulation of protein metabolic process; GO:0051129 (0.02) ! negative regulation of cellular component organization; GO:0051093 (0.02) ! negative regulation of developmental process; GO:0051050 (0.02) ! positive regulation of transport; GO:0048731 (0.02) ! system development; GO:0048729 (0.02) ! tissue morphogenesis; GO:0048646 (0.02) ! anatomical structure formation involved in morphogenesis; GO:0048638 (0.02) ! regulation of developmental growth; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0048468 (0.02) ! cell development; GO:0045926 (0.02) ! negative regulation of growth; GO:0045893 (0.02) ! positive regulation of transcription, DNA-templated; GO:0045892 (0.02) ! negative regulation of transcription, DNA-templated; GO:0045087 (0.02) ! innate immune response; GO:0044765 (0.02) ! single-organism transport; GO:0044710 (0.02) ! single-organism metabolic process; GO:0044700 (0.02) ! single organism signaling; GO:0044248 (0.02) ! cellular catabolic process; GO:0044089 (0.02) ! positive regulation of cellular component biogenesis; GO:0042742 (0.02) ! defense response to bacterium; GO:0034622 (0.02) ! cellular macromolecular complex assembly; GO:0034613 (0.02) ! cellular protein localization; GO:0033554 (0.02) ! cellular response to stress; GO:0032101 (0.02) ! regulation of response to external stimulus; GO:0031175 (0.02) ! neuron projection development; GO:0030154 (0.02) ! cell differentiation; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0022402 (0.02) ! cell cycle process; GO:0016192 (0.02) ! vesicle-mediated transport; GO:0016071 (0.02) ! mRNA metabolic process; GO:0010941 (0.02) ! regulation of cell death; GO:0009888 (0.02) ! tissue development; GO:0009886 (0.02) ! post-embryonic morphogenesis; GO:0009755 (0.02) ! hormone-mediated signaling pathway; GO:0009628 (0.02) ! response to abiotic stimulus; GO:0007610 (0.02) ! behavior; GO:0007600 (0.02) ! sensory perception; GO:0007275 (0.02) ! multicellular organism development; GO:0007190 (0.02) ! activation of adenylate cyclase activity; GO:0007189 (0.02) ! adenylate cyclase-activating G-protein coupled receptor signaling pathway; GO:0007154 (0.02) ! cell communication; GO:0007017 (0.02) ! microtubule-based process; GO:0006396 (0.02) ! RNA processing; GO:0006325 (0.02) ! chromatin organization; GO:0002237 (0.02) ! response to molecule of bacterial origin; GO:0001817 (0.02) ! regulation of cytokine production; GO:0001558 (0.02) ! regulation of cell growth; GO:2000021 (0.01) ! regulation of ion homeostasis; GO:1904064 (0.01) ! positive regulation of cation transmembrane transport; GO:1903047 (0.01) ! mitotic cell cycle process; GO:1902582 (0.01) ! single-organism intracellular transport; GO:1901990 (0.01) ! regulation of mitotic cell cycle phase transition; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:1901565 (0.01) ! organonitrogen compound catabolic process; GO:1901361 (0.01) ! organic cyclic compound catabolic process; GO:0090287 (0.01) ! regulation of cellular response to growth factor stimulus; GO:0090263 (0.01) ! positive regulation of canonical Wnt signaling pathway; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0071727 (0.01) ! cellular response to triacyl bacterial lipopeptide; GO:0071726 (0.01) ! cellular response to diacyl bacterial lipopeptide; GO:0071705 (0.01) ! nitrogen compound transport; GO:0071396 (0.01) ! cellular response to lipid; GO:0070647 (0.01) ! protein modification by small protein conjugation or removal; GO:0070374 (0.01) ! positive regulation of ERK1 and ERK2 cascade; GO:0060627 (0.01) ! regulation of vesicle-mediated transport; GO:0060271 (0.01) ! cilium morphogenesis; GO:0060026 (0.01) ! convergent extension; GO:0055085 (0.01) ! transmembrane transport; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0051965 (0.01) ! positive regulation of synapse assembly; GO:0051640 (0.01) ! organelle localization; GO:0051493 (0.01) ! regulation of cytoskeleton organization; GO:0051345 (0.01) ! positive regulation of hydrolase activity; GO:0051224 (0.01) ! negative regulation of protein transport; GO:0051222 (0.01) ! positive regulation of protein transport; GO:0051056 (0.01) ! regulation of small GTPase mediated signal transduction; GO:0051048 (0.01) ! negative regulation of secretion; GO:0050829 (0.01) ! defense response to Gram-negative bacterium; GO:0050708 (0.01) ! regulation of protein secretion; GO:0048608 (0.01) ! reproductive structure development; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046700 (0.01) ! heterocycle catabolic process; GO:0046331 (0.01) ! lateral inhibition; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045930 (0.01) ! negative regulation of mitotic cell cycle; GO:0045773 (0.01) ! positive regulation of axon extension; GO:0045359 (0.01) ! positive regulation of interferon-beta biosynthetic process; GO:0045356 (0.01) ! positive regulation of interferon-alpha biosynthetic process; GO:0045214 (0.01) ! sarcomere organization; GO:0045078 (0.01) ! positive regulation of interferon-gamma biosynthetic process; GO:0044802 (0.01) ! single-organism membrane organization; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0044719 (0.01) ! regulation of imaginal disc-derived wing size; GO:0044708 (0.01) ! single-organism behavior; GO:0044270 (0.01) ! cellular nitrogen compound catabolic process; GO:0044265 (0.01) ! cellular macromolecule catabolic process; GO:0043902 (0.01) ! positive regulation of multi-organism process; GO:0043623 (0.01) ! cellular protein complex assembly; GO:0043331 (0.01) ! response to dsRNA; GO:0043087 (0.01) ! regulation of GTPase activity; GO:0043069 (0.01) ! negative regulation of programmed cell death; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0042592 (0.01) ! homeostatic process; GO:0042116 (0.01) ! macrophage activation; GO:0042059 (0.01) ! negative regulation of epidermal growth factor receptor signaling pathway; GO:0040029 (0.01) ! regulation of gene expression, epigenetic; GO:0040017 (0.01) ! positive regulation of locomotion; GO:0040005 (0.01) ! chitin-based cuticle attachment to epithelium; GO:0035239 (0.01) ! tube morphogenesis; GO:0034660 (0.01) ! ncRNA metabolic process; GO:0034250 (0.01) ! positive regulation of cellular amide metabolic process; GO:0034154 (0.01) ! toll-like receptor 7 signaling pathway; GO:0034121 (0.01) ! regulation of toll-like receptor signaling pathway; GO:0034063 (0.01) ! stress granule assembly; GO:0033365 (0.01) ! protein localization to organelle; GO:0033157 (0.01) ! regulation of intracellular protein transport; GO:0033044 (0.01) ! regulation of chromosome organization; GO:0032970 (0.01) ! regulation of actin filament-based process; GO:0032886 (0.01) ! regulation of microtubule-based process; GO:0032757 (0.01) ! positive regulation of interleukin-8 production; GO:0032496 (0.01) ! response to lipopolysaccharide; GO:0032490 (0.01) ! detection of molecule of bacterial origin; GO:0032414 (0.01) ! positive regulation of ion transmembrane transporter activity; GO:0032388 (0.01) ! positive regulation of intracellular transport; GO:0032271 (0.01) ! regulation of protein polymerization; GO:0032103 (0.01) ! positive regulation of response to external stimulus; GO:0031334 (0.01) ! positive regulation of protein complex assembly; GO:0031290 (0.01) ! retinal ganglion cell axon guidance; GO:0031103 (0.01) ! axon regeneration; GO:0030517 (0.01) ! negative regulation of axon extension; GO:0030336 (0.01) ! negative regulation of cell migration; GO:0030198 (0.01) ! extracellular matrix organization; GO:0030155 (0.01) ! regulation of cell adhesion; GO:0022602 (0.01) ! ovulation cycle process; GO:0021952 (0.01) ! central nervous system projection neuron axonogenesis; GO:0019752 (0.01) ! carboxylic acid metabolic process; GO:0019730 (0.01) ! antimicrobial humoral response; GO:0019439 (0.01) ! aromatic compound catabolic process; GO:0019233 (0.01) ! sensory perception of pain; GO:0018205 (0.01) ! peptidyl-lysine modification; GO:0016570 (0.01) ! histone modification; GO:0016458 (0.01) ! gene silencing; GO:0010959 (0.01) ! regulation of metal ion transport; GO:0010927 (0.01) ! cellular component assembly involved in morphogenesis; GO:0010921 (0.01) ! regulation of phosphatase activity; GO:0010639 (0.01) ! negative regulation of organelle organization; GO:0010638 (0.01) ! positive regulation of organelle organization; GO:0010603 (0.01) ! regulation of cytoplasmic mRNA processing body assembly; GO:0009887 (0.01) ! organ morphogenesis; GO:0009790 (0.01) ! embryo development; GO:0009725 (0.01) ! response to hormone; GO:0009612 (0.01) ! response to mechanical stimulus; GO:0009416 (0.01) ! response to light stimulus; GO:0009306 (0.01) ! protein secretion; GO:0008362 (0.01) ! chitin-based embryonic cuticle biosynthetic process; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008045 (0.01) ! motor neuron axon guidance; GO:0008037 (0.01) ! cell recognition; GO:0007507 (0.01) ! heart development; GO:0007498 (0.01) ! mesoderm development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007475 (0.01) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.01) ! open tracheal system development; GO:0007420 (0.01) ! brain development; GO:0007417 (0.01) ! central nervous system development; GO:0007416 (0.01) ! synapse assembly; GO:0007297 (0.01) ! ovarian follicle cell migration; GO:0007283 (0.01) ! spermatogenesis; GO:0007169 (0.01) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007156 (0.01) ! homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007018 (0.01) ! microtubule-based movement; GO:0007015 (0.01) ! actin filament organization; GO:0006935 (0.01) ! chemotaxis; GO:0006913 (0.01) ! nucleocytoplasmic transport; GO:0006897 (0.01) ! endocytosis; GO:0006811 (0.01) ! ion transport; GO:0006351 (0.01) ! transcription, DNA-templated; GO:0006338 (0.01) ! chromatin remodeling; GO:0006259 (0.01) ! DNA metabolic process; GO:0003013 (0.01) ! circulatory system process; GO:0003002 (0.01) ! regionalization; GO:0002833 (0.01) ! positive regulation of response to biotic stimulus; GO:0002761 (0.01) ! regulation of myeloid leukocyte differentiation; GO:0002700 (0.01) ! regulation of production of molecular mediator of immune response; GO:0002683 (0.01) ! negative regulation of immune system process; GO:0001818 (0.01) ! negative regulation of cytokine production; GO:0001654 (0.01) ! eye development; GO:0000398 (0.01) ! mRNA splicing, via spliceosome; GO:0000226 (0.01) ! microtubule cytoskeleton organization; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter GO:0044464 (0.72) ! cell part; GO:0044424 (0.53) ! intracellular part; GO:0005737 (0.49) ! cytoplasm; GO:0044421 (0.30) ! extracellular region part; GO:0005615 (0.25) ! extracellular space; GO:0005578 (0.23) ! proteinaceous extracellular matrix; GO:0044425 (0.17) ! membrane part; GO:0031224 (0.15) ! intrinsic component of membrane; GO:0044459 (0.14) ! plasma membrane part; GO:0016021 (0.14) ! integral component of membrane; GO:0031226 (0.13) ! intrinsic component of plasma membrane; GO:0005887 (0.12) ! integral component of plasma membrane; GO:0016020 (0.11) ! membrane; GO:0005886 (0.09) ! plasma membrane; GO:0043227 (0.06) ! membrane-bounded organelle; GO:0070062 (0.04) ! extracellular exosome; GO:0044444 (0.04) ! cytoplasmic part; GO:0043234 (0.04) ! protein complex; GO:0044446 (0.02) ! intracellular organelle part; GO:0043231 (0.02) ! intracellular membrane-bounded organelle; GO:0042567 (0.02) ! insulin-like growth factor ternary complex; GO:0009986 (0.02) ! cell surface; GO:0060076 (0.01) ! excitatory synapse; GO:0046658 (0.01) ! anchored component of plasma membrane; GO:0043235 (0.01) ! receptor complex; GO:0032588 (0.01) ! trans-Golgi network membrane; GO:0030426 (0.01) ! growth cone; GO:0030425 (0.01) ! dendrite; GO:0009897 (0.01) ! external side of plasma membrane; GO:0008076 (0.01) ! voltage-gated potassium channel complex; GO:0005783 (0.01) ! endoplasmic reticulum; GO:0005774 (0.01) ! vacuolar membrane; GO:0005739 (0.01) ! mitochondrion; GO:0005576 (0.01) ! extracellular region GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 32007872-32053504 (17q11.2) Medium: lymph node (non-germinal center cells);placenta (decidual cells);small intestine (glandular cells);stomach 1 (glandular cells);bone marrow (hematopoietic cells);bronchus (respiratory epithelial cells);tonsil (non-germinal center cells);parathyroid gland (glandular cells);skeletal muscle (myocytes);vagina (squamous epithelial cells);salivary gland (glandular cells);colon (glandular cells);gallbladder (glandular cells);stomach 2 (glandular cells);heart muscle (myocytes);esophagus (squamous epithelial cells);oral mucosa (squamous epithelial cells);rectum (glandular cells);duodenum (glandular cells);Low: placenta (trophoblastic cells);testis (Leydig cells);seminal vesicle (glandular cells);tonsil (squamous epithelial cells);epididymis (glandular cells);adrenal gland (glandular cells);appendix (glandular cells);colon (peripheral nerve/ganglion);cervix, uterine (squamous epithelial cells);nasopharynx (respiratory epithelial cells);lung (macrophages);smooth muscle (smooth muscle cells);pancreas (exocrine glandular cells);skin 1 (keratinocytes; melanocytes);kidney (cells in tubules);liver (hepatocytes); Testis: 27.32; Brain - Cerebellar Hemisphere: 26.18; Brain - Cerebellum: 23.46; Ovary: 12.76; Skin - Sun Exposed (Lower leg): 11.04; Pituitary: 10.86; Uterus: 10.43; Skin - Not Sun Exposed (Suprapubic): 10.34; Cervix - Endocervix: 9.71; Nerve - Tibial: 9.69; Fallopian Tube: 8.79; Cervix - Ectocervix: 8.51; Vagina: 8.05; Bladder: 7.34; Brain - Frontal Cortex (BA9): 7.12; Lung: 7.06; Brain - Cortex: 6.87; Brain - Spinal cord (cervical c-1): 6.51; Artery - Aorta: 6.49; Artery - Tibial: 6.39; Breast - Mammary Tissue: 6.38; Colon - Sigmoid: 6.25; Spleen: 6.25; Prostate: 6.21; Adipose - Subcutaneous: 6.05; Artery - Coronary: 6.00; Thyroid: 5.98; Brain - Nucleus accumbens (basal ganglia): 5.89; Brain - Anterior cingulate cortex (BA24): 5.79; Brain - Hippocampus: 5.66; Brain - Caudate (basal ganglia): 5.59; Small Intestine - Terminal Ileum: 5.57; Brain - Hypothalamus: 5.49; Brain - Amygdala: 5.48; Esophagus - Gastroesophageal Junction: 5.39; Esophagus - Muscularis: 4.83; Cells - EBV-transformed lymphocytes: 4.82; Minor Salivary Gland: 4.70; Brain - Putamen (basal ganglia): 4.63; Adipose - Visceral (Omentum): 4.31; Brain - Substantia nigra: 4.18; Colon - Transverse: 3.98; Esophagus - Mucosa: 3.86; Whole Blood: 3.75; Cells - Transformed fibroblasts: 3.49; Adrenal Gland: 3.37; Stomach: 3.18; Kidney - Cortex: 2.01; Muscle - Skeletal: 1.77; Heart - Atrial Appendage: 1.53; Pancreas: 1.45; Liver: 0.96; Heart - Left Ventricle: 0.82; MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA TMEM98 Transmembrane protein 98 TMM98_HUMAN (Q9Y2Y6-1) GO:0046914 (0.50) ! transition metal ion binding; GO:0046906 (0.50) ! tetrapyrrole binding; GO:0016676 (0.50) ! oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor; GO:0015078 (0.50) ! hydrogen ion transmembrane transporter activity; GO:0015002 (0.50) ! heme-copper terminal oxidase activity; GO:0009055 (0.50) ! electron carrier activity GO:0098662 (0.50) ! inorganic cation transmembrane transport; GO:0046034 (0.50) ! ATP metabolic process; GO:0045333 (0.50) ! cellular respiration; GO:0016310 (0.50) ! phosphorylation; GO:0015672 (0.50) ! monovalent inorganic cation transport; GO:0006818 (0.50) ! hydrogen transport; GO:0050794 (0.35) ! regulation of cellular process GO:0043231 (1.00) ! intracellular membrane-bounded organelle; GO:0005634 (0.52) ! nucleus; GO:0005783 (0.48) ! endoplasmic reticulum; GO:0005654 (0.07) ! nucleoplasm; GO:0005737 (0.04) ! cytoplasm GO:0005783 ! endoplasmic reticulum GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 32927910-32945106 (17q11.2) Ovary: 109.90; Nerve - Tibial: 62.17; Uterus: 60.80; Fallopian Tube: 51.22; Cells - Transformed fibroblasts: 45.72; Cervix - Endocervix: 45.38; Artery - Aorta: 39.12; Cervix - Ectocervix: 36.70; Prostate: 35.99; Brain - Spinal cord (cervical c-1): 30.36; Vagina: 28.84; Thyroid: 28.33; Small Intestine - Terminal Ileum: 27.55; Stomach: 27.26; Colon - Transverse: 26.89; Lung: 26.77; Artery - Coronary: 23.72; Adipose - Visceral (Omentum): 23.69; Minor Salivary Gland: 23.41; Adrenal Gland: 21.43; Breast - Mammary Tissue: 20.57; Bladder: 19.68; Esophagus - Gastroesophageal Junction: 19.62; Colon - Sigmoid: 17.97; Artery - Tibial: 17.88; Esophagus - Muscularis: 16.57; Pancreas: 15.51; Brain - Hippocampus: 14.59; Adipose - Subcutaneous: 14.33; Testis: 14.08; Brain - Putamen (basal ganglia): 14.08; Brain - Substantia nigra: 13.37; Brain - Caudate (basal ganglia): 13.34; Skin - Sun Exposed (Lower leg): 12.79; Pituitary: 12.41; Heart - Atrial Appendage: 11.45; Brain - Amygdala: 11.04; Brain - Nucleus accumbens (basal ganglia): 10.78; Skin - Not Sun Exposed (Suprapubic): 10.29; Kidney - Cortex: 9.96; Brain - Hypothalamus: 9.90; Spleen: 9.64; Esophagus - Mucosa: 9.29; Brain - Cerebellum: 8.78; Brain - Cerebellar Hemisphere: 8.26; Brain - Cortex: 7.10; Brain - Frontal Cortex (BA9): 6.37; Brain - Anterior cingulate cortex (BA24): 6.33; Liver: 3.73; Heart - Left Ventricle: 2.88; Muscle - Skeletal: 1.00; Whole Blood: 0.11; Cells - EBV-transformed lymphocytes: 0.10; METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI FNDC8 Fibronectin type III domain-containing protein 8 FNDC8_HUMAN (Q8TC99-1) GO:0003824 (0.61) ! catalytic activity; GO:0097367 (0.51) ! carbohydrate derivative binding; GO:1901363 (0.50) ! heterocyclic compound binding; GO:0097159 (0.50) ! organic cyclic compound binding; GO:0035639 (0.49) ! purine ribonucleoside triphosphate binding; GO:0032559 (0.49) ! adenyl ribonucleotide binding; GO:0032550 (0.49) ! purine ribonucleoside binding; GO:0016740 (0.37) ! transferase activity; GO:0004872 (0.37) ! receptor activity; GO:0016787 (0.35) ! hydrolase activity; GO:0004888 (0.35) ! transmembrane signaling receptor activity; GO:0004672 (0.35) ! protein kinase activity; GO:0008186 (0.31) ! RNA-dependent ATPase activity; GO:0008026 (0.31) ! ATP-dependent helicase activity; GO:0003724 (0.31) ! RNA helicase activity; GO:0004713 (0.28) ! protein tyrosine kinase activity; GO:0042802 (0.22) ! identical protein binding; GO:0046983 (0.17) ! protein dimerization activity; GO:0042803 (0.16) ! protein homodimerization activity; GO:0008046 (0.14) ! axon guidance receptor activity; GO:0004714 (0.13) ! transmembrane receptor protein tyrosine kinase activity; GO:0003823 (0.12) ! antigen binding; GO:0005003 (0.11) ! ephrin receptor activity; GO:0005198 (0.10) ! structural molecule activity; GO:0044877 (0.09) ! macromolecular complex binding; GO:0032403 (0.08) ! protein complex binding; GO:0008092 (0.08) ! cytoskeletal protein binding; GO:0008307 (0.07) ! structural constituent of muscle; GO:0050839 (0.06) ! cell adhesion molecule binding; GO:0004725 (0.06) ! protein tyrosine phosphatase activity; GO:0005102 (0.05) ! receptor binding; GO:1901681 (0.04) ! sulfur compound binding; GO:0097493 (0.04) ! structural molecule activity conferring elasticity; GO:0051371 (0.04) ! muscle alpha-actinin binding; GO:0051015 (0.04) ! actin filament binding; GO:0019899 (0.04) ! enzyme binding; GO:0019838 (0.04) ! growth factor binding; GO:0005539 (0.04) ! glycosaminoglycan binding; GO:0005001 (0.04) ! transmembrane receptor protein tyrosine phosphatase activity; GO:0004674 (0.04) ! protein serine/threonine kinase activity; GO:0045296 (0.03) ! cadherin binding; GO:0043548 (0.03) ! phosphatidylinositol 3-kinase binding; GO:0008201 (0.03) ! heparin binding; GO:0005200 (0.03) ! structural constituent of cytoskeleton; GO:0005005 (0.03) ! transmembrane-ephrin receptor activity; GO:0004896 (0.03) ! cytokine receptor activity; GO:0098772 (0.02) ! molecular function regulator; GO:0046982 (0.02) ! protein heterodimerization activity; GO:0019904 (0.02) ! protein domain specific binding; GO:0005520 (0.02) ! insulin-like growth factor binding; GO:0005518 (0.02) ! collagen binding; GO:0005004 (0.02) ! GPI-linked ephrin receptor activity; GO:0004687 (0.02) ! myosin light chain kinase activity; GO:0004683 (0.02) ! calmodulin-dependent protein kinase activity; GO:0098632 (0.01) ! protein binding involved in cell-cell adhesion; GO:0097161 (0.01) ! DH domain binding; GO:0051219 (0.01) ! phosphoprotein binding; GO:0046873 (0.01) ! metal ion transmembrane transporter activity; GO:0046872 (0.01) ! metal ion binding; GO:0045295 (0.01) ! gamma-catenin binding; GO:0044822 (0.01) ! poly(A) RNA binding; GO:0043621 (0.01) ! protein self-association; GO:0038132 (0.01) ! neuregulin binding; GO:0038021 (0.01) ! leptin receptor activity; GO:0032036 (0.01) ! myosin heavy chain binding; GO:0031994 (0.01) ! insulin-like growth factor I binding; GO:0030506 (0.01) ! ankyrin binding; GO:0019955 (0.01) ! cytokine binding; GO:0019902 (0.01) ! phosphatase binding; GO:0019901 (0.01) ! protein kinase binding; GO:0017046 (0.01) ! peptide hormone binding; GO:0008047 (0.01) ! enzyme activator activity; GO:0008017 (0.01) ! microtubule binding; GO:0008013 (0.01) ! beta-catenin binding; GO:0005261 (0.01) ! cation channel activity; GO:0005178 (0.01) ! integrin binding; GO:0005127 (0.01) ! ciliary neurotrophic factor receptor binding; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0005042 (0.01) ! netrin receptor activity; GO:0004923 (0.01) ! leukemia inhibitory factor receptor activity; GO:0004842 (0.01) ! ubiquitin-protein transferase activity; GO:0003713 (0.01) ! transcription coactivator activity; GO:0002020 (0.01) ! protease binding GO:0044699 (0.83) ! single-organism process; GO:0009987 (0.83) ! cellular process; GO:0044763 (0.77) ! single-organism cellular process; GO:0065007 (0.72) ! biological regulation; GO:0050789 (0.72) ! regulation of biological process; GO:0050794 (0.69) ! regulation of cellular process; GO:0032502 (0.67) ! developmental process; GO:0044767 (0.63) ! single-organism developmental process; GO:0048856 (0.54) ! anatomical structure development; GO:0048869 (0.52) ! cellular developmental process; GO:0071704 (0.41) ! organic substance metabolic process; GO:0044238 (0.40) ! primary metabolic process; GO:0044237 (0.40) ! cellular metabolic process; GO:0043170 (0.40) ! macromolecule metabolic process; GO:0006928 (0.40) ! movement of cell or subcellular component; GO:0044260 (0.39) ! cellular macromolecule metabolic process; GO:0016043 (0.39) ! cellular component organization; GO:0019538 (0.36) ! protein metabolic process; GO:0006464 (0.35) ! cellular protein modification process; GO:0009653 (0.34) ! anatomical structure morphogenesis; GO:0006796 (0.34) ! phosphate-containing compound metabolic process; GO:0051239 (0.32) ! regulation of multicellular organismal process; GO:0007411 (0.32) ! axon guidance; GO:2000026 (0.30) ! regulation of multicellular organismal development; GO:0051128 (0.30) ! regulation of cellular component organization; GO:0016310 (0.30) ! phosphorylation; GO:0006468 (0.29) ! protein phosphorylation; GO:0048468 (0.28) ! cell development; GO:0048518 (0.27) ! positive regulation of biological process; GO:0045595 (0.27) ! regulation of cell differentiation; GO:0019222 (0.27) ! regulation of metabolic process; GO:0080090 (0.26) ! regulation of primary metabolic process; GO:0051960 (0.26) ! regulation of nervous system development; GO:0048583 (0.26) ! regulation of response to stimulus; GO:0031323 (0.26) ! regulation of cellular metabolic process; GO:0050767 (0.25) ! regulation of neurogenesis; GO:0040007 (0.25) ! growth; GO:0022603 (0.25) ! regulation of anatomical structure morphogenesis; GO:0060255 (0.24) ! regulation of macromolecule metabolic process; GO:0045664 (0.24) ! regulation of neuron differentiation; GO:0031344 (0.24) ! regulation of cell projection organization; GO:0008038 (0.24) ! neuron recognition; GO:0050896 (0.23) ! response to stimulus; GO:0030154 (0.23) ! cell differentiation; GO:0016049 (0.23) ! cell growth; GO:0010975 (0.23) ! regulation of neuron projection development; GO:0007165 (0.23) ! signal transduction; GO:0007155 (0.23) ! cell adhesion; GO:0048522 (0.22) ! positive regulation of cellular process; GO:0010769 (0.22) ! regulation of cell morphogenesis involved in differentiation; GO:0009966 (0.22) ! regulation of signal transduction; GO:0051179 (0.21) ! localization; GO:0050770 (0.21) ! regulation of axonogenesis; GO:0040011 (0.20) ! locomotion; GO:0032501 (0.20) ! multicellular organismal process; GO:0007413 (0.20) ! axonal fasciculation; GO:0016477 (0.19) ! cell migration; GO:1902531 (0.18) ! regulation of intracellular signal transduction; GO:0032268 (0.18) ! regulation of cellular protein metabolic process; GO:0019220 (0.18) ! regulation of phosphate metabolic process; GO:0007166 (0.18) ! cell surface receptor signaling pathway; GO:0048513 (0.17) ! animal organ development; GO:0042221 (0.17) ! response to chemical; GO:0030030 (0.17) ! cell projection organization; GO:0001932 (0.17) ! regulation of protein phosphorylation; GO:0048731 (0.16) ! system development; GO:0048523 (0.16) ! negative regulation of cellular process; GO:0032989 (0.16) ! cellular component morphogenesis; GO:0051234 (0.15) ! establishment of localization; GO:0043408 (0.15) ! regulation of MAPK cascade; GO:0022607 (0.15) ! cellular component assembly; GO:1902578 (0.14) ! single-organism localization; GO:0070372 (0.14) ! regulation of ERK1 and ERK2 cascade; GO:0051240 (0.14) ! positive regulation of multicellular organismal process; GO:0051130 (0.14) ! positive regulation of cellular component organization; GO:0051094 (0.14) ! positive regulation of developmental process; GO:0048646 (0.14) ! anatomical structure formation involved in morphogenesis; GO:0010033 (0.14) ! response to organic substance; GO:0006810 (0.14) ! transport; GO:0098602 (0.13) ! single organism cell adhesion; GO:0065009 (0.13) ! regulation of molecular function; GO:0048589 (0.13) ! developmental growth; GO:0044765 (0.13) ! single-organism transport; GO:0030155 (0.13) ! regulation of cell adhesion; GO:0016192 (0.13) ! vesicle-mediated transport; GO:0008283 (0.13) ! cell proliferation; GO:0007167 (0.13) ! enzyme linked receptor protein signaling pathway; GO:0006996 (0.13) ! organelle organization; GO:0051962 (0.12) ! positive regulation of nervous system development; GO:0050790 (0.12) ! regulation of catalytic activity; GO:0048812 (0.12) ! neuron projection morphogenesis; GO:0044707 (0.12) ! single-multicellular organism process; GO:0032006 (0.12) ! regulation of TOR signaling; GO:0009628 (0.12) ! response to abiotic stimulus; GO:0009605 (0.12) ! response to external stimulus; GO:0007169 (0.12) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0006909 (0.12) ! phagocytosis; GO:0002066 (0.12) ! columnar/cuboidal epithelial cell development; GO:0098609 (0.11) ! cell-cell adhesion; GO:0050773 (0.11) ! regulation of dendrite development; GO:0048675 (0.11) ! axon extension; GO:0048666 (0.11) ! neuron development; GO:0046777 (0.11) ! protein autophosphorylation; GO:0044087 (0.11) ! regulation of cellular component biogenesis; GO:0032879 (0.11) ! regulation of localization; GO:0031589 (0.11) ! cell-substrate adhesion; GO:0016319 (0.11) ! mushroom body development; GO:0070593 (0.10) ! dendrite self-avoidance; GO:0051336 (0.10) ! regulation of hydrolase activity; GO:0050982 (0.10) ! detection of mechanical stimulus; GO:0050906 (0.10) ! detection of stimulus involved in sensory perception; GO:0048846 (0.10) ! axon extension involved in axon guidance; GO:0048814 (0.10) ! regulation of dendrite morphogenesis; GO:0048013 (0.10) ! ephrin receptor signaling pathway; GO:0044089 (0.10) ! positive regulation of cellular component biogenesis; GO:0043933 (0.10) ! macromolecular complex subunit organization; GO:0007422 (0.10) ! peripheral nervous system development; GO:0007419 (0.10) ! ventral cord development; GO:0003008 (0.10) ! system process; GO:0002237 (0.10) ! response to molecule of bacterial origin; GO:0000904 (0.10) ! cell morphogenesis involved in differentiation; GO:0065003 (0.09) ! macromolecular complex assembly; GO:0051963 (0.09) ! regulation of synapse assembly; GO:0051270 (0.09) ! regulation of cellular component movement; GO:0050976 (0.09) ! detection of mechanical stimulus involved in sensory perception of touch; GO:0043087 (0.09) ! regulation of GTPase activity; GO:0040012 (0.09) ! regulation of locomotion; GO:0034446 (0.09) ! substrate adhesion-dependent cell spreading; GO:0032490 (0.09) ! detection of molecule of bacterial origin; GO:0021551 (0.09) ! central nervous system morphogenesis; GO:2000145 (0.08) ! regulation of cell motility; GO:1902589 (0.08) ! single-organism organelle organization; GO:0065008 (0.08) ! regulation of biological quality; GO:0051965 (0.08) ! positive regulation of synapse assembly; GO:0044710 (0.08) ! single-organism metabolic process; GO:0034622 (0.08) ! cellular macromolecular complex assembly; GO:0033036 (0.08) ! macromolecule localization; GO:0022407 (0.08) ! regulation of cell-cell adhesion; GO:0010941 (0.08) ! regulation of cell death; GO:0010468 (0.08) ! regulation of gene expression; GO:0070727 (0.07) ! cellular macromolecule localization; GO:0060997 (0.07) ! dendritic spine morphogenesis; GO:0060996 (0.07) ! dendritic spine development; GO:0042981 (0.07) ! regulation of apoptotic process; GO:0030334 (0.07) ! regulation of cell migration; GO:0030036 (0.07) ! actin cytoskeleton organization; GO:0006950 (0.07) ! response to stress; GO:0006355 (0.07) ! regulation of transcription, DNA-templated; GO:1901360 (0.06) ! organic cyclic compound metabolic process; GO:0080134 (0.06) ! regulation of response to stress; GO:0051241 (0.06) ! negative regulation of multicellular organismal process; GO:0051093 (0.06) ! negative regulation of developmental process; GO:0048729 (0.06) ! tissue morphogenesis; GO:0048585 (0.06) ! negative regulation of response to stimulus; GO:0048584 (0.06) ! positive regulation of response to stimulus; GO:0045597 (0.06) ! positive regulation of cell differentiation; GO:0045214 (0.06) ! sarcomere organization; GO:0043632 (0.06) ! modification-dependent macromolecule catabolic process; GO:0032101 (0.06) ! regulation of response to external stimulus; GO:0022414 (0.06) ! reproductive process; GO:0016337 (0.06) ! single organismal cell-cell adhesion; GO:0009888 (0.06) ! tissue development; GO:0007156 (0.06) ! homophilic cell adhesion via plasma membrane adhesion molecules; GO:0006936 (0.06) ! muscle contraction; GO:0006725 (0.06) ! cellular aromatic compound metabolic process; GO:0071822 (0.05) ! protein complex subunit organization; GO:0071051 (0.05) ! polyadenylation-dependent snoRNA 3'-end processing; GO:0071049 (0.05) ! nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription; GO:0071042 (0.05) ! nuclear polyadenylation-dependent mRNA catabolic process; GO:0071038 (0.05) ! nuclear polyadenylation-dependent tRNA catabolic process; GO:0071035 (0.05) ! nuclear polyadenylation-dependent rRNA catabolic process; GO:0055114 (0.05) ! oxidation-reduction process; GO:0051716 (0.05) ! cellular response to stimulus; GO:0048638 (0.05) ! regulation of developmental growth; GO:0044702 (0.05) ! single organism reproductive process; GO:0043629 (0.05) ! ncRNA polyadenylation; GO:0042127 (0.05) ! regulation of cell proliferation; GO:0034476 (0.05) ! U5 snRNA 3'-end processing; GO:0034475 (0.05) ! U4 snRNA 3'-end processing; GO:0032508 (0.05) ! DNA duplex unwinding; GO:0031175 (0.05) ! neuron projection development; GO:0018193 (0.05) ! peptidyl-amino acid modification; GO:0010976 (0.05) ! positive regulation of neuron projection development; GO:0010604 (0.05) ! positive regulation of macromolecule metabolic process; GO:0010501 (0.05) ! RNA secondary structure unwinding; GO:0006310 (0.05) ! DNA recombination; GO:0003002 (0.05) ! regionalization; GO:0001649 (0.05) ! osteoblast differentiation; GO:0000716 (0.05) ! transcription-coupled nucleotide-excision repair, DNA damage recognition; GO:0000467 (0.05) ! exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); GO:0000388 (0.05) ! spliceosome conformational change to release U4 (or U4atac) and U1 (or U11); GO:0000354 (0.05) ! cis assembly of pre-catalytic spliceosome; GO:0080135 (0.04) ! regulation of cellular response to stress; GO:0060415 (0.04) ! muscle tissue morphogenesis; GO:0050768 (0.04) ! negative regulation of neurogenesis; GO:0048747 (0.04) ! muscle fiber development; GO:0045785 (0.04) ! positive regulation of cell adhesion; GO:0044093 (0.04) ! positive regulation of molecular function; GO:0043066 (0.04) ! negative regulation of apoptotic process; GO:0042592 (0.04) ! homeostatic process; GO:0035556 (0.04) ! intracellular signal transduction; GO:0033043 (0.04) ! regulation of organelle organization; GO:0032270 (0.04) ! positive regulation of cellular protein metabolic process; GO:0032102 (0.04) ! negative regulation of response to external stimulus; GO:0030516 (0.04) ! regulation of axon extension; GO:0018108 (0.04) ! peptidyl-tyrosine phosphorylation; GO:0010927 (0.04) ! cellular component assembly involved in morphogenesis; GO:0009968 (0.04) ! negative regulation of signal transduction; GO:0009967 (0.04) ! positive regulation of signal transduction; GO:0009887 (0.04) ! organ morphogenesis; GO:0007409 (0.04) ! axonogenesis; GO:0007015 (0.04) ! actin filament organization; GO:0006470 (0.04) ! protein dephosphorylation; GO:0006461 (0.04) ! protein complex assembly; GO:1902533 (0.03) ! positive regulation of intracellular signal transduction; GO:1901700 (0.03) ! response to oxygen-containing compound; GO:1901342 (0.03) ! regulation of vasculature development; GO:1901215 (0.03) ! negative regulation of neuron death; GO:0070887 (0.03) ! cellular response to chemical stimulus; GO:0055008 (0.03) ! cardiac muscle tissue morphogenesis; GO:0051493 (0.03) ! regulation of cytoskeleton organization; GO:0051049 (0.03) ! regulation of transport; GO:0050877 (0.03) ! neurological system process; GO:0048739 (0.03) ! cardiac muscle fiber development; GO:0048639 (0.03) ! positive regulation of developmental growth; GO:0048609 (0.03) ! multicellular organismal reproductive process; GO:0043523 (0.03) ! regulation of neuron apoptotic process; GO:0033554 (0.03) ! cellular response to stress; GO:0032970 (0.03) ! regulation of actin filament-based process; GO:0032940 (0.03) ! secretion by cell; GO:0031347 (0.03) ! regulation of defense response; GO:0031290 (0.03) ! retinal ganglion cell axon guidance; GO:0031099 (0.03) ! regeneration; GO:0030336 (0.03) ! negative regulation of cell migration; GO:0030335 (0.03) ! positive regulation of cell migration; GO:0030241 (0.03) ! skeletal muscle myosin thick filament assembly; GO:0030239 (0.03) ! myofibril assembly; GO:0030198 (0.03) ! extracellular matrix organization; GO:0030182 (0.03) ! neuron differentiation; GO:0016199 (0.03) ! axon midline choice point recognition; GO:0010977 (0.03) ! negative regulation of neuron projection development; GO:0010842 (0.03) ! retina layer formation; GO:0010810 (0.03) ! regulation of cell-substrate adhesion; GO:0010770 (0.03) ! positive regulation of cell morphogenesis involved in differentiation; GO:0010632 (0.03) ! regulation of epithelial cell migration; GO:0009719 (0.03) ! response to endogenous stimulus; GO:0009611 (0.03) ! response to wounding; GO:0008104 (0.03) ! protein localization; GO:0008045 (0.03) ! motor neuron axon guidance; GO:0007399 (0.03) ! nervous system development; GO:0006941 (0.03) ! striated muscle contraction; GO:0003006 (0.03) ! developmental process involved in reproduction; GO:0002682 (0.03) ! regulation of immune system process; GO:0002376 (0.03) ! immune system process; GO:0001934 (0.03) ! positive regulation of protein phosphorylation; GO:0001775 (0.03) ! cell activation; GO:0001667 (0.03) ! ameboidal-type cell migration; GO:0001525 (0.03) ! angiogenesis; GO:1903036 (0.02) ! positive regulation of response to wounding; GO:1901701 (0.02) ! cellular response to oxygen-containing compound; GO:0071310 (0.02) ! cellular response to organic substance; GO:0070527 (0.02) ! platelet aggregation; GO:0070050 (0.02) ! neuron cellular homeostasis; GO:0060429 (0.02) ! epithelium development; GO:0060341 (0.02) ! regulation of cellular localization; GO:0055003 (0.02) ! cardiac myofibril assembly; GO:0051704 (0.02) ! multi-organism process; GO:0051223 (0.02) ! regulation of protein transport; GO:0051098 (0.02) ! regulation of binding; GO:0050920 (0.02) ! regulation of chemotaxis; GO:0050772 (0.02) ! positive regulation of axonogenesis; GO:0050728 (0.02) ! negative regulation of inflammatory response; GO:0050680 (0.02) ! negative regulation of epithelial cell proliferation; GO:0048679 (0.02) ! regulation of axon regeneration; GO:0048608 (0.02) ! reproductive structure development; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0045859 (0.02) ! regulation of protein kinase activity; GO:0045824 (0.02) ! negative regulation of innate immune response; GO:0044057 (0.02) ! regulation of system process; GO:0043524 (0.02) ! negative regulation of neuron apoptotic process; GO:0043491 (0.02) ! protein kinase B signaling; GO:0043410 (0.02) ! positive regulation of MAPK cascade; GO:0043277 (0.02) ! apoptotic cell clearance; GO:0043085 (0.02) ! positive regulation of catalytic activity; GO:0042698 (0.02) ! ovulation cycle; GO:0042493 (0.02) ! response to drug; GO:0035295 (0.02) ! tube development; GO:0035239 (0.02) ! tube morphogenesis; GO:0034613 (0.02) ! cellular protein localization; GO:0034122 (0.02) ! negative regulation of toll-like receptor signaling pathway; GO:0033993 (0.02) ! response to lipid; GO:0032956 (0.02) ! regulation of actin cytoskeleton organization; GO:0032872 (0.02) ! regulation of stress-activated MAPK cascade; GO:0032103 (0.02) ! positive regulation of response to external stimulus; GO:0031324 (0.02) ! negative regulation of cellular metabolic process; GO:0031103 (0.02) ! axon regeneration; GO:0030517 (0.02) ! negative regulation of axon extension; GO:0030240 (0.02) ! skeletal muscle thin filament assembly; GO:0030168 (0.02) ! platelet activation; GO:0021952 (0.02) ! central nervous system projection neuron axonogenesis; GO:0021885 (0.02) ! forebrain cell migration; GO:0019221 (0.02) ! cytokine-mediated signaling pathway; GO:0016525 (0.02) ! negative regulation of angiogenesis; GO:0014070 (0.02) ! response to organic cyclic compound; GO:0010906 (0.02) ! regulation of glucose metabolic process; GO:0010811 (0.02) ! positive regulation of cell-substrate adhesion; GO:0010638 (0.02) ! positive regulation of organelle organization; GO:0010605 (0.02) ! negative regulation of macromolecule metabolic process; GO:0010594 (0.02) ! regulation of endothelial cell migration; GO:0009725 (0.02) ! response to hormone; GO:0008284 (0.02) ! positive regulation of cell proliferation; GO:0007610 (0.02) ! behavior; GO:0007498 (0.02) ! mesoderm development; GO:0007420 (0.02) ! brain development; GO:0007417 (0.02) ! central nervous system development; GO:0007416 (0.02) ! synapse assembly; GO:0007283 (0.02) ! spermatogenesis; GO:0007154 (0.02) ! cell communication; GO:0006952 (0.02) ! defense response; GO:0006935 (0.02) ! chemotaxis; GO:0002009 (0.02) ! morphogenesis of an epithelium; GO:0001936 (0.02) ! regulation of endothelial cell proliferation; GO:0001764 (0.02) ! neuron migration; GO:0001756 (0.02) ! somitogenesis; GO:2001108 (0.01) ! positive regulation of Rho guanyl-nucleotide exchange factor activity; GO:2000505 (0.01) ! regulation of energy homeostasis; GO:2000274 (0.01) ! regulation of epithelial cell migration, open tracheal system; GO:1903955 (0.01) ! positive regulation of protein targeting to mitochondrion; GO:1903047 (0.01) ! mitotic cell cycle process; GO:1902580 (0.01) ! single-organism cellular localization; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1901654 (0.01) ! response to ketone; GO:0098868 (0.01) ! bone growth; GO:0098779 (0.01) ! mitophagy in response to mitochondrial depolarization; GO:0097156 (0.01) ! fasciculation of motor neuron axon; GO:0097155 (0.01) ! fasciculation of sensory neuron axon; GO:0097090 (0.01) ! presynaptic membrane organization; GO:0097009 (0.01) ! energy homeostasis; GO:0090257 (0.01) ! regulation of muscle system process; GO:0071689 (0.01) ! muscle thin filament assembly; GO:0071679 (0.01) ! commissural neuron axon guidance; GO:0071407 (0.01) ! cellular response to organic cyclic compound; GO:0071396 (0.01) ! cellular response to lipid; GO:0071229 (0.01) ! cellular response to acid chemical; GO:0070983 (0.01) ! dendrite guidance; GO:0070848 (0.01) ! response to growth factor; GO:0070507 (0.01) ! regulation of microtubule cytoskeleton organization; GO:0070374 (0.01) ! positive regulation of ERK1 and ERK2 cascade; GO:0070309 (0.01) ! lens fiber cell morphogenesis; GO:0070301 (0.01) ! cellular response to hydrogen peroxide; GO:0070252 (0.01) ! actin-mediated cell contraction; GO:0060562 (0.01) ! epithelial tube morphogenesis; GO:0060326 (0.01) ! cell chemotaxis; GO:0060259 (0.01) ! regulation of feeding behavior; GO:0060219 (0.01) ! camera-type eye photoreceptor cell differentiation; GO:0055010 (0.01) ! ventricular cardiac muscle tissue morphogenesis; GO:0051897 (0.01) ! positive regulation of protein kinase B signaling; GO:0051893 (0.01) ! regulation of focal adhesion assembly; GO:0051656 (0.01) ! establishment of organelle localization; GO:0051649 (0.01) ! establishment of localization in cell; GO:0051496 (0.01) ! positive regulation of stress fiber assembly; GO:0051345 (0.01) ! positive regulation of hydrolase activity; GO:0051249 (0.01) ! regulation of lymphocyte activation; GO:0051149 (0.01) ! positive regulation of muscle cell differentiation; GO:0050922 (0.01) ! negative regulation of chemotaxis; GO:0050905 (0.01) ! neuromuscular process; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0050803 (0.01) ! regulation of synapse structure or activity; GO:0050792 (0.01) ! regulation of viral process; GO:0050731 (0.01) ! positive regulation of peptidyl-tyrosine phosphorylation; GO:0050708 (0.01) ! regulation of protein secretion; GO:0050673 (0.01) ! epithelial cell proliferation; GO:0048841 (0.01) ! regulation of axon extension involved in axon guidance; GO:0048813 (0.01) ! dendrite morphogenesis; GO:0048771 (0.01) ! tissue remodeling; GO:0048741 (0.01) ! skeletal muscle fiber development; GO:0048738 (0.01) ! cardiac muscle tissue development; GO:0048681 (0.01) ! negative regulation of axon regeneration; GO:0048680 (0.01) ! positive regulation of axon regeneration; GO:0048670 (0.01) ! regulation of collateral sprouting; GO:0048251 (0.01) ! elastic fiber assembly; GO:0048036 (0.01) ! central complex development; GO:0046850 (0.01) ! regulation of bone remodeling; GO:0046425 (0.01) ! regulation of JAK-STAT cascade; GO:0045887 (0.01) ! positive regulation of synaptic growth at neuromuscular junction; GO:0045862 (0.01) ! positive regulation of proteolysis; GO:0045860 (0.01) ! positive regulation of protein kinase activity; GO:0045773 (0.01) ! positive regulation of axon extension; GO:0045766 (0.01) ! positive regulation of angiogenesis; GO:0045598 (0.01) ! regulation of fat cell differentiation; GO:0045216 (0.01) ! cell-cell junction organization; GO:0045184 (0.01) ! establishment of protein localization; GO:0045161 (0.01) ! neuronal ion channel clustering; GO:0045055 (0.01) ! regulated exocytosis; GO:0044321 (0.01) ! response to leptin; GO:0043506 (0.01) ! regulation of JUN kinase activity; GO:0043393 (0.01) ! regulation of protein binding; GO:0043281 (0.01) ! regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0043254 (0.01) ! regulation of protein complex assembly; GO:0043161 (0.01) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0042593 (0.01) ! glucose homeostasis; GO:0042475 (0.01) ! odontogenesis of dentin-containing tooth; GO:0042462 (0.01) ! eye photoreceptor cell development; GO:0042391 (0.01) ! regulation of membrane potential; GO:0042246 (0.01) ! tissue regeneration; GO:0042074 (0.01) ! cell migration involved in gastrulation; GO:0042060 (0.01) ! wound healing; GO:0042059 (0.01) ! negative regulation of epidermal growth factor receptor signaling pathway; GO:0035418 (0.01) ! protein localization to synapse; GO:0035385 (0.01) ! Roundabout signaling pathway; GO:0035372 (0.01) ! protein localization to microtubule; GO:0035050 (0.01) ! embryonic heart tube development; GO:0035025 (0.01) ! positive regulation of Rho protein signal transduction; GO:0035017 (0.01) ! cuticle pattern formation; GO:0035011 (0.01) ! melanotic encapsulation of foreign target; GO:0034097 (0.01) ! response to cytokine; GO:0033564 (0.01) ! anterior/posterior axon guidance; GO:0033563 (0.01) ! dorsal/ventral axon guidance; GO:0033210 (0.01) ! leptin-mediated signaling pathway; GO:0032963 (0.01) ! collagen metabolic process; GO:0032870 (0.01) ! cellular response to hormone stimulus; GO:0032526 (0.01) ! response to retinoic acid; GO:0032496 (0.01) ! response to lipopolysaccharide; GO:0031100 (0.01) ! organ regeneration; GO:0030855 (0.01) ! epithelial cell differentiation; GO:0030534 (0.01) ! adult behavior; GO:0030217 (0.01) ! T cell differentiation; GO:0030199 (0.01) ! collagen fibril organization; GO:0030031 (0.01) ! cell projection assembly; GO:0030010 (0.01) ! establishment of cell polarity; GO:0022412 (0.01) ! cellular process involved in reproduction in multicellular organism; GO:0022409 (0.01) ! positive regulation of cell-cell adhesion; GO:0022008 (0.01) ! neurogenesis; GO:0021961 (0.01) ! posterior commissure morphogenesis; GO:0021891 (0.01) ! olfactory bulb interneuron development; GO:0021772 (0.01) ! olfactory bulb development; GO:0021554 (0.01) ! optic nerve development; GO:0021510 (0.01) ! spinal cord development; GO:0019953 (0.01) ! sexual reproduction; GO:0016202 (0.01) ! regulation of striated muscle tissue development; GO:0014814 (0.01) ! axon regeneration at neuromuscular junction; GO:0010628 (0.01) ! positive regulation of gene expression; GO:0010596 (0.01) ! negative regulation of endothelial cell migration; GO:0010507 (0.01) ! negative regulation of autophagy; GO:0010243 (0.01) ! response to organonitrogen compound; GO:0010172 (0.01) ! embryonic body morphogenesis; GO:0010038 (0.01) ! response to metal ion; GO:0009953 (0.01) ! dorsal/ventral pattern formation; GO:0009880 (0.01) ! embryonic pattern specification; GO:0009792 (0.01) ! embryo development ending in birth or egg hatching; GO:0008589 (0.01) ! regulation of smoothened signaling pathway; GO:0008406 (0.01) ! gonad development; GO:0008366 (0.01) ! axon ensheathment; GO:0008347 (0.01) ! glial cell migration; GO:0008039 (0.01) ! synaptic target recognition; GO:0007626 (0.01) ! locomotory behavior; GO:0007612 (0.01) ! learning; GO:0007606 (0.01) ! sensory perception of chemical stimulus; GO:0007596 (0.01) ! blood coagulation; GO:0007584 (0.01) ! response to nutrient; GO:0007527 (0.01) ! adult somatic muscle development; GO:0007520 (0.01) ! myoblast fusion; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007507 (0.01) ! heart development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007432 (0.01) ! salivary gland boundary specification; GO:0007424 (0.01) ! open tracheal system development; GO:0007267 (0.01) ! cell-cell signaling; GO:0007224 (0.01) ! smoothened signaling pathway; GO:0007162 (0.01) ! negative regulation of cell adhesion; GO:0007160 (0.01) ! cell-matrix adhesion; GO:0007158 (0.01) ! neuron cell-cell adhesion; GO:0007157 (0.01) ! heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0007044 (0.01) ! cell-substrate junction assembly; GO:0006939 (0.01) ! smooth muscle contraction; GO:0006812 (0.01) ! cation transport; GO:0006641 (0.01) ! triglyceride metabolic process; GO:0006631 (0.01) ! fatty acid metabolic process; GO:0006469 (0.01) ! negative regulation of protein kinase activity; GO:0003262 (0.01) ! endocardial progenitor cell migration to the midline involved in heart field formation; GO:0003211 (0.01) ! cardiac ventricle formation; GO:0003210 (0.01) ! cardiac atrium formation; GO:0003151 (0.01) ! outflow tract morphogenesis; GO:0003128 (0.01) ! heart field specification; GO:0003013 (0.01) ! circulatory system process; GO:0003007 (0.01) ! heart morphogenesis; GO:0002697 (0.01) ! regulation of immune effector process; GO:0002684 (0.01) ! positive regulation of immune system process; GO:0002042 (0.01) ! cell migration involved in sprouting angiogenesis; GO:0002027 (0.01) ! regulation of heart rate; GO:0001954 (0.01) ! positive regulation of cell-matrix adhesion; GO:0001937 (0.01) ! negative regulation of endothelial cell proliferation; GO:0001841 (0.01) ! neural tube formation; GO:0001822 (0.01) ! kidney development; GO:0001817 (0.01) ! regulation of cytokine production; GO:0001763 (0.01) ! morphogenesis of a branching structure; GO:0001755 (0.01) ! neural crest cell migration; GO:0001751 (0.01) ! compound eye photoreceptor cell differentiation; GO:0001745 (0.01) ! compound eye morphogenesis; GO:0001708 (0.01) ! cell fate specification; GO:0001666 (0.01) ! response to hypoxia; GO:0001657 (0.01) ! ureteric bud development; GO:0001654 (0.01) ! eye development; GO:0001570 (0.01) ! vasculogenesis; GO:0001568 (0.01) ! blood vessel development; GO:0000226 (0.01) ! microtubule cytoskeleton organization; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter GO:0044464 (1.00) ! cell part; GO:0005634 (0.96) ! nucleus; GO:0005887 (0.04) ! integral component of plasma membrane GO:0005634 ! nucleus 2 35121579-35130732 (17q12) High: testis (elongated or late spermatids);Medium: testis (round or early spermatids);Low: testis (Leydig cells; pachytene spermatocytes; preleptotene spermatocytes; sertoli cells; spermatogonia); Testis: 172.80; Cervix - Ectocervix: 0.37; Fallopian Tube: 0.36; Cells - Transformed fibroblasts: 0.34; Cells - EBV-transformed lymphocytes: 0.30; Brain - Cerebellum: 0.25; Ovary: 0.23; Brain - Cerebellar Hemisphere: 0.21; Cervix - Endocervix: 0.17; Skin - Not Sun Exposed (Suprapubic): 0.17; Skin - Sun Exposed (Lower leg): 0.17; Spleen: 0.14; Brain - Frontal Cortex (BA9): 0.14; Brain - Cortex: 0.14; Adipose - Subcutaneous: 0.14; Prostate: 0.12; Nerve - Tibial: 0.12; Thyroid: 0.12; Esophagus - Mucosa: 0.11; Breast - Mammary Tissue: 0.11; Uterus: 0.11; Small Intestine - Terminal Ileum: 0.11; Brain - Nucleus accumbens (basal ganglia): 0.11; Adipose - Visceral (Omentum): 0.10; Vagina: 0.10; Bladder: 0.10; Brain - Anterior cingulate cortex (BA24): 0.09; Lung: 0.09; Artery - Coronary: 0.08; Artery - Tibial: 0.08; Colon - Transverse: 0.08; Colon - Sigmoid: 0.07; Brain - Caudate (basal ganglia): 0.07; Minor Salivary Gland: 0.07; Brain - Amygdala: 0.07; Artery - Aorta: 0.07; Stomach: 0.06; Brain - Hypothalamus: 0.06; Esophagus - Muscularis: 0.06; Esophagus - Gastroesophageal Junction: 0.06; Kidney - Cortex: 0.06; Pituitary: 0.06; Brain - Substantia nigra: 0.06; Brain - Spinal cord (cervical c-1): 0.05; Brain - Putamen (basal ganglia): 0.05; Muscle - Skeletal: 0.04; Brain - Hippocampus: 0.04; Pancreas: 0.04; MASEALHQVGDGEEAVLKKENFNMMNALDQLPKPFSNPKSMNRTVTTKGLPLASKGNLVNFLEDDTINLLKPLPVEDSDCSSDETSISAFSSTLLNPIKLAVTQPNSSFFAGMLEGELNKLSFSPMAKNAENEDLALGPCPCPSKSQMATRGLLDLDNPELETETSSTHSESSVVVDLPDTPFIFEHTVNNSTAVISWTYALGKQPVSFYQLLLQEVAKTQENELPEAKNRPWIFNKILGTTVKLMELKPNTCYCLSVRAANTAGVGKWCKPYKFATLATDFSSFPENYPIQITVRRKEPRQKIVSIGPEEMRRLEDLEYLFPC C17orf50 Uncharacterized protein C17orf50 CQ050_HUMAN (Q8WW18-1) GO:0046982 (0.12) ! protein heterodimerization activity; GO:0008601 (0.12) ! protein phosphatase type 2A regulator activity; GO:0004722 (0.12) ! protein serine/threonine phosphatase activity; GO:0003823 (0.12) ! antigen binding GO:2001241 (0.12) ! positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; GO:1903538 (0.12) ! regulation of meiotic cell cycle process involved in oocyte maturation; GO:0070262 (0.12) ! peptidyl-serine dephosphorylation; GO:0051754 (0.12) ! meiotic sister chromatid cohesion, centromeric; GO:0051306 (0.12) ! mitotic sister chromatid separation; GO:0051232 (0.12) ! meiotic spindle elongation; GO:0042518 (0.12) ! negative regulation of tyrosine phosphorylation of Stat3 protein; GO:0034047 (0.12) ! regulation of protein phosphatase type 2A activity; GO:0030308 (0.12) ! negative regulation of cell growth; GO:0030155 (0.12) ! regulation of cell adhesion; GO:0030111 (0.12) ! regulation of Wnt signaling pathway; GO:0019932 (0.12) ! second-messenger-mediated signaling; GO:0010033 (0.12) ! response to organic substance; GO:0008380 (0.12) ! RNA splicing; GO:0007143 (0.12) ! female meiotic division; GO:0007084 (0.12) ! mitotic nuclear envelope reassembly; GO:0006672 (0.12) ! ceramide metabolic process; GO:0006461 (0.12) ! protein complex assembly; GO:0006355 (0.12) ! regulation of transcription, DNA-templated; GO:0006275 (0.12) ! regulation of DNA replication; GO:0000188 (0.12) ! inactivation of MAPK activity; GO:0000184 (0.12) ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0000086 (0.12) ! G2/M transition of mitotic cell cycle GO:0044446 (1.00) ! intracellular organelle part; GO:0005737 (1.00) ! cytoplasm; GO:0043657 (0.90) ! host cell; GO:0070062 (0.77) ! extracellular exosome; GO:0016020 (0.77) ! membrane; GO:0005829 (0.77) ! cytosol; GO:0005634 (0.77) ! nucleus; GO:0044428 (0.56) ! nuclear part; GO:0072372 (0.37) ! primary cilium; GO:0034399 (0.37) ! nuclear periphery; GO:0031965 (0.37) ! nuclear membrane; GO:0015630 (0.37) ! microtubule cytoskeleton; GO:0005739 (0.37) ! mitochondrion; GO:0005694 (0.37) ! chromosome; GO:0000775 (0.37) ! chromosome, centromeric region; GO:0000159 (0.37) ! protein phosphatase type 2A complex; GO:0005643 (0.18) ! nuclear pore 1 35760897-35765079 (17q12) Testis: 203.00; Brain - Nucleus accumbens (basal ganglia): 1.74; Brain - Caudate (basal ganglia): 1.10; Brain - Cerebellar Hemisphere: 1.07; Brain - Cerebellum: 1.04; Brain - Putamen (basal ganglia): 0.88; Brain - Hypothalamus: 0.82; Brain - Frontal Cortex (BA9): 0.77; Brain - Cortex: 0.72; Brain - Anterior cingulate cortex (BA24): 0.65; Pituitary: 0.64; Nerve - Tibial: 0.58; Thyroid: 0.57; Brain - Amygdala: 0.51; Brain - Hippocampus: 0.46; Brain - Substantia nigra: 0.41; Bladder: 0.37; Fallopian Tube: 0.30; Colon - Transverse: 0.27; Skin - Not Sun Exposed (Suprapubic): 0.26; Lung: 0.25; Small Intestine - Terminal Ileum: 0.25; Brain - Spinal cord (cervical c-1): 0.23; Cervix - Endocervix: 0.23; Esophagus - Muscularis: 0.22; Esophagus - Gastroesophageal Junction: 0.21; Skin - Sun Exposed (Lower leg): 0.21; Artery - Coronary: 0.17; Spleen: 0.17; Stomach: 0.17; Pancreas: 0.17; Adipose - Visceral (Omentum): 0.15; Breast - Mammary Tissue: 0.15; Prostate: 0.15; Adrenal Gland: 0.15; Colon - Sigmoid: 0.15; Kidney - Cortex: 0.14; Vagina: 0.13; Adipose - Subcutaneous: 0.13; Esophagus - Mucosa: 0.13; Cervix - Ectocervix: 0.11; Artery - Tibial: 0.11; Minor Salivary Gland: 0.10; Uterus: 0.06; Ovary: 0.05; Artery - Aorta: 0.05; Whole Blood: 0.04; Heart - Atrial Appendage: 0.04; Muscle - Skeletal: 0.04; MDKHGVKTPLWKKETEELRAEDAEQEEGKEGSEDEDEDNQRPLEDSATEGEEPPRVAEEGEGRERRSVSYCPLRQESSTQQVALLRRADSGFWGWLGPLALLGGLTAPTDRKRSLPEEPCVLEIRRRPPRRGGCACCELLFCKKCRSLHSHPAYVAHCVLDHPDLGKAGAAGNS C17orf98 Uncharacterized protein C17orf98 CQ098_HUMAN (A8MV24-1) GO:0015926 (0.48) ! glucosidase activity GO:0051275 (0.37) ! beta-glucan catabolic process; GO:0030243 (0.37) ! cellulose metabolic process GO:0005576 (0.75) ! extracellular region; GO:0009507 (0.25) ! chloroplast 1 38835088-38841455 (17q12) Testis: 39.71; Cells - EBV-transformed lymphocytes: 0.12; Adrenal Gland: 0.10; Adipose - Visceral (Omentum): 0.09; Thyroid: 0.09; Prostate: 0.09; Ovary: 0.09; Pituitary: 0.09; Breast - Mammary Tissue: 0.08; Adipose - Subcutaneous: 0.07; MAYLSECRLRLEKGFILDGVAVSTAARAYGRSRPKLWSAIPPYNAQQDYHARSYFQSHVVPPLLRKTDQDHGGTGRDGWIVDYIHIFGQGQRYLNRRNWAGTGHSLQQVTGHDHYNADLKPIDGFNGRFGYRRNTPALRQSTSVFGEVTHFPLF HSPB9 Heat shock protein beta-9 HSPB9_HUMAN (Q9BQS6-1) GO:0042802 (0.76) ! identical protein binding; GO:0042803 (0.63) ! protein homodimerization activity; GO:0051082 (0.52) ! unfolded protein binding; GO:0005212 (0.50) ! structural constituent of eye lens; GO:0032182 (0.39) ! ubiquitin-like protein binding; GO:0030291 (0.39) ! protein serine/threonine kinase inhibitor activity; GO:0019900 (0.39) ! kinase binding; GO:0003723 (0.37) ! RNA binding; GO:0043169 (0.35) ! cation binding; GO:0043130 (0.07) ! ubiquitin binding; GO:0008426 (0.07) ! protein kinase C inhibitor activity; GO:0005080 (0.07) ! protein kinase C binding; GO:0044822 (0.05) ! poly(A) RNA binding; GO:0008017 (0.03) ! microtubule binding; GO:0008022 (0.02) ! protein C-terminus binding GO:0050896 (0.82) ! response to stimulus; GO:0006950 (0.80) ! response to stress; GO:0009987 (0.75) ! cellular process; GO:0009628 (0.71) ! response to abiotic stimulus; GO:0065007 (0.63) ! biological regulation; GO:0050789 (0.63) ! regulation of biological process; GO:0044699 (0.63) ! single-organism process; GO:0042221 (0.60) ! response to chemical; GO:0009408 (0.60) ! response to heat; GO:0050794 (0.58) ! regulation of cellular process; GO:0016043 (0.56) ! cellular component organization; GO:0044763 (0.53) ! single-organism cellular process; GO:0044767 (0.52) ! single-organism developmental process; GO:0048523 (0.51) ! negative regulation of cellular process; GO:0042981 (0.51) ! regulation of apoptotic process; GO:0006457 (0.51) ! protein folding; GO:0043066 (0.50) ! negative regulation of apoptotic process; GO:0022607 (0.49) ! cellular component assembly; GO:1901700 (0.48) ! response to oxygen-containing compound; GO:0048856 (0.48) ! anatomical structure development; GO:0031323 (0.48) ! regulation of cellular metabolic process; GO:0010035 (0.48) ! response to inorganic substance; GO:0010033 (0.48) ! response to organic substance; GO:0006979 (0.48) ! response to oxidative stress; GO:0080090 (0.47) ! regulation of primary metabolic process; GO:0060255 (0.47) ! regulation of macromolecule metabolic process; GO:0000302 (0.47) ! response to reactive oxygen species; GO:0032268 (0.46) ! regulation of cellular protein metabolic process; GO:0006461 (0.46) ! protein complex assembly; GO:0032501 (0.45) ! multicellular organismal process; GO:0051239 (0.44) ! regulation of multicellular organismal process; GO:0032879 (0.44) ! regulation of localization; GO:0031324 (0.43) ! negative regulation of cellular metabolic process; GO:0010468 (0.43) ! regulation of gene expression; GO:0048522 (0.42) ! positive regulation of cellular process; GO:0043086 (0.42) ! negative regulation of catalytic activity; GO:0032269 (0.42) ! negative regulation of cellular protein metabolic process; GO:0031326 (0.42) ! regulation of cellular biosynthetic process; GO:0010556 (0.42) ! regulation of macromolecule biosynthetic process; GO:0009314 (0.42) ! response to radiation; GO:0006996 (0.42) ! organelle organization; GO:1902589 (0.41) ! single-organism organelle organization; GO:0080135 (0.41) ! regulation of cellular response to stress; GO:0051247 (0.41) ! positive regulation of protein metabolic process; GO:0051128 (0.41) ! regulation of cellular component organization; GO:0042325 (0.41) ! regulation of phosphorylation; GO:0031399 (0.41) ! regulation of protein modification process; GO:0031325 (0.41) ! positive regulation of cellular metabolic process; GO:0008152 (0.41) ! metabolic process; GO:0007010 (0.41) ! cytoskeleton organization; GO:2000112 (0.40) ! regulation of cellular macromolecule biosynthetic process; GO:0065008 (0.40) ! regulation of biological quality; GO:0051704 (0.40) ! multi-organism process; GO:0051171 (0.40) ! regulation of nitrogen compound metabolic process; GO:0044237 (0.40) ! cellular metabolic process; GO:0035966 (0.40) ! response to topologically incorrect protein; GO:0009605 (0.40) ! response to external stimulus; GO:0007165 (0.40) ! signal transduction; GO:0001932 (0.40) ! regulation of protein phosphorylation; GO:1903202 (0.39) ! negative regulation of oxidative stress-induced cell death; GO:0051707 (0.39) ! response to other organism; GO:0051240 (0.39) ! positive regulation of multicellular organismal process; GO:0036293 (0.39) ! response to decreased oxygen levels; GO:0035556 (0.39) ! intracellular signal transduction; GO:0030036 (0.39) ! actin cytoskeleton organization; GO:0009416 (0.39) ! response to light stimulus; GO:0006417 (0.39) ! regulation of translation; GO:0001654 (0.39) ! eye development; GO:2001243 (0.38) ! negative regulation of intrinsic apoptotic signaling pathway; GO:2000117 (0.38) ! negative regulation of cysteine-type endopeptidase activity; GO:2000026 (0.38) ! regulation of multicellular organismal development; GO:1902742 (0.38) ! apoptotic process involved in development; GO:1902175 (0.38) ! regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0051094 (0.38) ! positive regulation of developmental process; GO:0045859 (0.38) ! regulation of protein kinase activity; GO:0043623 (0.38) ! cellular protein complex assembly; GO:0043281 (0.38) ! regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0043010 (0.38) ! camera-type eye development; GO:0042534 (0.38) ! regulation of tumor necrosis factor biosynthetic process; GO:0042108 (0.38) ! positive regulation of cytokine biosynthetic process; GO:0033673 (0.38) ! negative regulation of kinase activity; GO:0032760 (0.38) ! positive regulation of tumor necrosis factor production; GO:0032732 (0.38) ! positive regulation of interleukin-1 production; GO:0032651 (0.38) ! regulation of interleukin-1 beta production; GO:0001933 (0.38) ! negative regulation of protein phosphorylation; GO:0001558 (0.38) ! regulation of cell growth; GO:2001028 (0.37) ! positive regulation of endothelial cell chemotaxis; GO:1904018 (0.37) ! positive regulation of vasculature development; GO:0048010 (0.37) ! vascular endothelial growth factor receptor signaling pathway; GO:0045765 (0.37) ! regulation of angiogenesis; GO:0043535 (0.37) ! regulation of blood vessel endothelial cell migration; GO:0038089 (0.37) ! positive regulation of cell migration by vascular endothelial growth factor signaling pathway; GO:0034109 (0.37) ! homotypic cell-cell adhesion; GO:0016032 (0.37) ! viral process; GO:0009653 (0.37) ! anatomical structure morphogenesis; GO:0048048 (0.36) ! embryonic eye morphogenesis; GO:0045927 (0.36) ! positive regulation of growth; GO:0044057 (0.36) ! regulation of system process; GO:0042327 (0.36) ! positive regulation of phosphorylation; GO:0031401 (0.36) ! positive regulation of protein modification process; GO:0009411 (0.36) ! response to UV; GO:0002089 (0.36) ! lens morphogenesis in camera-type eye; GO:0000904 (0.36) ! cell morphogenesis involved in differentiation; GO:0090257 (0.35) ! regulation of muscle system process; GO:0071900 (0.35) ! regulation of protein serine/threonine kinase activity; GO:0070307 (0.35) ! lens fiber cell development; GO:0043487 (0.35) ! regulation of RNA stability; GO:0031076 (0.35) ! embryonic camera-type eye development; GO:0001894 (0.35) ! tissue homeostasis; GO:0030168 (0.34) ! platelet activation; GO:0007249 (0.34) ! I-kappaB kinase/NF-kappaB signaling; GO:0006914 (0.34) ! autophagy; GO:0006413 (0.34) ! translational initiation; GO:0044707 (0.33) ! single-multicellular organism process; GO:0019538 (0.33) ! protein metabolic process; GO:0006937 (0.31) ! regulation of muscle contraction; GO:0044710 (0.28) ! single-organism metabolic process; GO:0008340 (0.28) ! determination of adult lifespan; GO:0044268 (0.26) ! multicellular organismal protein metabolic process; GO:0009792 (0.26) ! embryo development ending in birth or egg hatching; GO:0051716 (0.24) ! cellular response to stimulus; GO:0042542 (0.18) ! response to hydrogen peroxide; GO:0033554 (0.15) ! cellular response to stress; GO:0003008 (0.15) ! system process; GO:0051259 (0.14) ! protein oligomerization; GO:0042026 (0.14) ! protein refolding; GO:0051260 (0.13) ! protein homooligomerization; GO:0032387 (0.12) ! negative regulation of intracellular transport; GO:0006468 (0.09) ! protein phosphorylation; GO:0070887 (0.08) ! cellular response to chemical stimulus; GO:0010506 (0.08) ! regulation of autophagy; GO:0006986 (0.08) ! response to unfolded protein; GO:0006446 (0.08) ! regulation of translational initiation; GO:0071310 (0.07) ! cellular response to organic substance; GO:0046685 (0.07) ! response to arsenic-containing substance; GO:0033993 (0.07) ! response to lipid; GO:0032535 (0.07) ! regulation of cellular component size; GO:0014070 (0.07) ! response to organic cyclic compound; GO:0010038 (0.07) ! response to metal ion; GO:0009719 (0.07) ! response to endogenous stimulus; GO:0007601 (0.07) ! visual perception; GO:0006928 (0.07) ! movement of cell or subcellular component; GO:0002088 (0.07) ! lens development in camera-type eye; GO:1902176 (0.06) ! negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:0043122 (0.06) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0042535 (0.06) ! positive regulation of tumor necrosis factor biosynthetic process; GO:0032731 (0.06) ! positive regulation of interleukin-1 beta production; GO:0031032 (0.06) ! actomyosin structure organization; GO:0010998 (0.06) ! regulation of translational initiation by eIF2 alpha phosphorylation; GO:0006497 (0.06) ! protein lipidation; GO:0006469 (0.06) ! negative regulation of protein kinase activity; GO:0001666 (0.06) ! response to hypoxia; GO:0071907 (0.05) ! determination of digestive tract left/right asymmetry; GO:0071480 (0.05) ! cellular response to gamma radiation; GO:0061371 (0.05) ! determination of heart left/right asymmetry; GO:0060972 (0.05) ! left/right pattern formation; GO:0060561 (0.05) ! apoptotic process involved in morphogenesis; GO:0060047 (0.05) ! heart contraction; GO:0043154 (0.05) ! negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; GO:0040011 (0.05) ! locomotion; GO:0030239 (0.05) ! myofibril assembly; GO:0014881 (0.05) ! regulation of myofibril size; GO:0010629 (0.05) ! negative regulation of gene expression; GO:0009615 (0.05) ! response to virus; GO:0007626 (0.05) ! locomotory behavior; GO:0007519 (0.05) ! skeletal muscle tissue development; GO:0007021 (0.05) ! tubulin complex assembly; GO:0007017 (0.05) ! microtubule-based process; GO:1990267 (0.04) ! response to transition metal nanoparticle; GO:0070527 (0.04) ! platelet aggregation; GO:0070121 (0.04) ! Kupffer's vesicle development; GO:0061077 (0.04) ! chaperone-mediated protein folding; GO:0045766 (0.04) ! positive regulation of angiogenesis; GO:0043536 (0.04) ! positive regulation of blood vessel endothelial cell migration; GO:0038033 (0.04) ! positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; GO:0035924 (0.04) ! cellular response to vascular endothelial growth factor stimulus; GO:0010243 (0.04) ! response to organonitrogen compound; GO:0009725 (0.04) ! response to hormone; GO:0009644 (0.04) ! response to high light intensity; GO:0007568 (0.04) ! aging; GO:0003319 (0.04) ! cardioblast migration to the midline involved in heart rudiment formation; GO:1900034 (0.03) ! regulation of cellular response to heat; GO:0061061 (0.03) ! muscle structure development; GO:0046688 (0.03) ! response to copper ion; GO:0046686 (0.03) ! response to cadmium ion; GO:0045926 (0.03) ! negative regulation of growth; GO:0045471 (0.03) ! response to ethanol; GO:0034599 (0.03) ! cellular response to oxidative stress; GO:2000378 (0.02) ! negative regulation of reactive oxygen species metabolic process; GO:1990776 (0.02) ! response to angiotensin; GO:1903545 (0.02) ! cellular response to butyrate; GO:0071901 (0.02) ! negative regulation of protein serine/threonine kinase activity; GO:0071348 (0.02) ! cellular response to interleukin-11; GO:0070309 (0.02) ! lens fiber cell morphogenesis; GO:0070301 (0.02) ! cellular response to hydrogen peroxide; GO:0070141 (0.02) ! response to UV-A; GO:0051403 (0.02) ! stress-activated MAPK cascade; GO:0051384 (0.02) ! response to glucocorticoid; GO:0051016 (0.02) ! barbed-end actin filament capping; GO:0048596 (0.02) ! embryonic camera-type eye morphogenesis; GO:0043488 (0.02) ! regulation of mRNA stability; GO:0042742 (0.02) ! defense response to bacterium; GO:0042594 (0.02) ! response to starvation; GO:0042493 (0.02) ! response to drug; GO:0035994 (0.02) ! response to muscle stretch; GO:0034605 (0.02) ! cellular response to heat; GO:0032355 (0.02) ! response to estradiol; GO:0031109 (0.02) ! microtubule polymerization or depolymerization; GO:0030968 (0.02) ! endoplasmic reticulum unfolded protein response; GO:0030308 (0.02) ! negative regulation of cell growth; GO:0030307 (0.02) ! positive regulation of cell growth; GO:0010976 (0.02) ! positive regulation of neuron projection development; GO:0010288 (0.02) ! response to lead ion; GO:0010286 (0.02) ! heat acclimation; GO:0009631 (0.02) ! cold acclimation; GO:0008016 (0.02) ! regulation of heart contraction; GO:0007565 (0.02) ! female pregnancy; GO:0007517 (0.02) ! muscle organ development; GO:0007015 (0.02) ! actin filament organization; GO:0007005 (0.02) ! mitochondrion organization; GO:0006936 (0.02) ! muscle contraction; GO:0002931 (0.02) ! response to ischemia; GO:0001934 (0.02) ! positive regulation of protein phosphorylation; GO:0001895 (0.02) ! retina homeostasis; GO:1990169 (0.01) ! stress response to copper ion; GO:0071456 (0.01) ! cellular response to hypoxia; GO:0052572 (0.01) ! response to host immune response; GO:0051409 (0.01) ! response to nitrosative stress; GO:0050832 (0.01) ! defense response to fungus; GO:0050829 (0.01) ! defense response to Gram-negative bacterium; GO:0046777 (0.01) ! protein autophosphorylation; GO:0045214 (0.01) ! sarcomere organization; GO:0044121 (0.01) ! growth of symbiont in host organelle; GO:0042595 (0.01) ! behavioral response to starvation; GO:0031427 (0.01) ! response to methotrexate; GO:0010039 (0.01) ! response to iron ion; GO:0009651 (0.01) ! response to salt stress; GO:0009267 (0.01) ! cellular response to starvation; GO:0007525 (0.01) ! somatic muscle development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0006972 (0.01) ! hyperosmotic response; GO:0006810 (0.01) ! transport; GO:0006355 (0.01) ! regulation of transcription, DNA-templated GO:0044424 (1.00) ! intracellular part; GO:0005634 (0.97) ! nucleus; GO:0005737 (0.96) ! cytoplasm; GO:0044422 (0.10) ! organelle part; GO:0044444 (0.09) ! cytoplasmic part; GO:0070062 (0.08) ! extracellular exosome; GO:0044449 (0.07) ! contractile fiber part; GO:0043232 (0.07) ! intracellular non-membrane-bounded organelle; GO:0044446 (0.06) ! intracellular organelle part; GO:0043292 (0.06) ! contractile fiber; GO:0016020 (0.06) ! membrane; GO:0030018 (0.05) ! Z disc; GO:0005829 (0.05) ! cytosol; GO:0005886 (0.04) ! plasma membrane; GO:0005654 (0.04) ! nucleoplasm; GO:0000502 (0.03) ! proteasome complex; GO:0097512 (0.02) ! cardiac myofibril; GO:0097060 (0.02) ! synaptic membrane; GO:0045202 (0.02) ! synapse; GO:0043204 (0.02) ! perikaryon; GO:0031674 (0.02) ! I band; GO:0031430 (0.02) ! M band; GO:0030424 (0.02) ! axon; GO:0016235 (0.02) ! aggresome; GO:0005925 (0.02) ! focal adhesion; GO:0005856 (0.02) ! cytoskeleton; GO:0005739 (0.02) ! mitochondrion; GO:0005622 (0.02) ! intracellular; GO:0005615 (0.02) ! extracellular space; GO:0098839 (0.01) ! postsynaptic density membrane; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0043209 (0.01) ! myelin sheath; GO:0043197 (0.01) ! dendritic spine; GO:0032432 (0.01) ! actin filament bundle; GO:0031012 (0.01) ! extracellular matrix; GO:0030425 (0.01) ! dendrite; GO:0015630 (0.01) ! microtubule cytoskeleton; GO:0014069 (0.01) ! postsynaptic density; GO:0009986 (0.01) ! cell surface; GO:0005794 (0.01) ! Golgi apparatus GO:0005737 ! cytoplasm; GO:0005634 ! nucleus; GO:0005515 ! protein binding 3 GO:0005515 ! protein binding 42121431-42123352 (17q21.2) Testis: 94.63; Liver: 5.04; Pancreas: 2.31; Pituitary: 2.14; Ovary: 2.10; Prostate: 1.32; Fallopian Tube: 1.08; Colon - Sigmoid: 1.07; Spleen: 1.07; Uterus: 1.03; Bladder: 0.98; Brain - Nucleus accumbens (basal ganglia): 0.92; Esophagus - Gastroesophageal Junction: 0.90; Brain - Cerebellar Hemisphere: 0.88; Brain - Cerebellum: 0.85; Esophagus - Muscularis: 0.85; Stomach: 0.82; Cervix - Endocervix: 0.78; Kidney - Cortex: 0.76; Vagina: 0.73; Breast - Mammary Tissue: 0.72; Nerve - Tibial: 0.71; Brain - Caudate (basal ganglia): 0.70; Thyroid: 0.70; Minor Salivary Gland: 0.69; Adipose - Visceral (Omentum): 0.68; Lung: 0.68; Brain - Putamen (basal ganglia): 0.61; Small Intestine - Terminal Ileum: 0.61; Brain - Hypothalamus: 0.59; Adipose - Subcutaneous: 0.58; Cervix - Ectocervix: 0.54; Skin - Not Sun Exposed (Suprapubic): 0.53; Colon - Transverse: 0.53; Skin - Sun Exposed (Lower leg): 0.52; Adrenal Gland: 0.51; Brain - Spinal cord (cervical c-1): 0.47; Whole Blood: 0.44; Esophagus - Mucosa: 0.43; Brain - Frontal Cortex (BA9): 0.42; Artery - Coronary: 0.41; Brain - Cortex: 0.40; Artery - Aorta: 0.36; Cells - EBV-transformed lymphocytes: 0.35; Brain - Hippocampus: 0.35; Brain - Substantia nigra: 0.33; Brain - Amygdala: 0.29; Brain - Anterior cingulate cortex (BA24): 0.29; Muscle - Skeletal: 0.25; Heart - Atrial Appendage: 0.24; Artery - Tibial: 0.24; Cells - Transformed fibroblasts: 0.20; Heart - Left Ventricle: 0.14; MQRVGNTFSNESRVASRCPSVGLAERNRVATMPVRLLRDSPAAQEDNDHARDGFQMKLDAHGFAPEELVVQVDGQWLMVTGQQQLDVRDPERVSYRMSQKVHRKMLPSNLSPTAMTCCLTPSGQLWVRGQCVALALPEAQTGPSPRLGSLGSKASNLTR TMEM106A Transmembrane protein 106A T106A_HUMAN (Q96A25-1) GO:0008236 (0.36) ! serine-type peptidase activity; GO:0004175 (0.36) ! endopeptidase activity GO:0048813 (1.00) ! dendrite morphogenesis; GO:0032418 (1.00) ! lysosome localization; GO:0007041 (0.93) ! lysosomal transport; GO:0007040 (0.93) ! lysosome organization; GO:0019538 (0.22) ! protein metabolic process; GO:1900006 (0.07) ! positive regulation of dendrite development GO:0016020 (0.97) ! membrane; GO:0044424 (0.28) ! intracellular part; GO:0005765 (0.26) ! lysosomal membrane; GO:0043227 (0.13) ! membrane-bounded organelle; GO:0070062 (0.11) ! extracellular exosome; GO:0043231 (0.06) ! intracellular membrane-bounded organelle; GO:0005764 (0.02) ! lysosome GO:0016020 ! membrane GO:0016021 ! integral component of membrane 2 43211835-43220041 (17q21.31) Cells - EBV-transformed lymphocytes: 15.57; Spleen: 14.54; Cervix - Endocervix: 9.18; Ovary: 8.45; Lung: 8.28; Cervix - Ectocervix: 8.23; Thyroid: 8.00; Kidney - Cortex: 7.20; Testis: 7.16; Uterus: 7.11; Artery - Aorta: 6.58; Nerve - Tibial: 6.52; Fallopian Tube: 6.50; Adipose - Subcutaneous: 6.14; Artery - Coronary: 6.06; Adipose - Visceral (Omentum): 5.77; Breast - Mammary Tissue: 5.08; Small Intestine - Terminal Ileum: 4.79; Prostate: 4.74; Cells - Transformed fibroblasts: 4.29; Whole Blood: 4.14; Vagina: 4.09; Minor Salivary Gland: 4.07; Bladder: 3.97; Artery - Tibial: 3.87; Colon - Sigmoid: 3.50; Esophagus - Gastroesophageal Junction: 3.36; Colon - Transverse: 3.28; Adrenal Gland: 3.10; Esophagus - Muscularis: 3.04; Pituitary: 2.81; Stomach: 2.76; Brain - Spinal cord (cervical c-1): 2.70; Pancreas: 2.05; Heart - Atrial Appendage: 1.75; Skin - Sun Exposed (Lower leg): 1.60; Skin - Not Sun Exposed (Suprapubic): 1.32; Esophagus - Mucosa: 1.27; Brain - Substantia nigra: 1.25; Liver: 1.20; Brain - Hypothalamus: 1.02; Brain - Caudate (basal ganglia): 0.82; Brain - Nucleus accumbens (basal ganglia): 0.79; Heart - Left Ventricle: 0.77; Brain - Hippocampus: 0.77; Brain - Amygdala: 0.69; Brain - Putamen (basal ganglia): 0.59; Brain - Frontal Cortex (BA9): 0.53; Brain - Anterior cingulate cortex (BA24): 0.52; Brain - Cortex: 0.51; Muscle - Skeletal: 0.51; Brain - Cerebellum: 0.44; Brain - Cerebellar Hemisphere: 0.42; MGKTFSQLGSWREDENKSILSSKPAIGSKAVNYSSTGSSKSFCSCVPCEGTADASFVTCPTCQGSGKIPQELEKQLVALIPYGDQRLKPKHTKLFVFLAVLICLVTSSFIVFFLFPRSVIVQPAGLNSSTVAFDEADIYLNITNILNISNGNYYPIMVTQLTLEVLHLSLVVGQVSNNLLLHIGPLASEQMFYAVATKIRDENTYKICTWLEIKVHHVLLHIQGTLTCSYLSHSEQLVFQSYEYVDCRGNASVPHQLTPHPP C17orf105 Uncharacterized protein C17orf105 CF97D_HUMAN (B2RV13-1) GO:0003824 (0.95) ! catalytic activity; GO:0016740 (0.44) ! transferase activity; GO:0004842 (0.41) ! ubiquitin-protein transferase activity; GO:0004185 (0.36) ! serine-type carboxypeptidase activity; GO:0004181 (0.36) ! metallocarboxypeptidase activity; GO:0003755 (0.19) ! peptidyl-prolyl cis-trans isomerase activity; GO:0043565 (0.09) ! sequence-specific DNA binding; GO:0030412 (0.09) ! formimidoyltetrahydrofolate cyclodeaminase activity; GO:0003690 (0.09) ! double-stranded DNA binding; GO:0030409 (0.05) ! glutamate formimidoyltransferase activity; GO:0019903 (0.05) ! protein phosphatase binding; GO:0019215 (0.05) ! intermediate filament binding; GO:0008017 (0.05) ! microtubule binding; GO:0005542 (0.05) ! folic acid binding; GO:0005102 (0.05) ! receptor binding; GO:0004871 (0.05) ! signal transducer activity; GO:0003700 (0.05) ! transcription factor activity, sequence-specific DNA binding; GO:0003691 (0.05) ! double-stranded telomeric DNA binding; GO:0000979 (0.05) ! RNA polymerase II core promoter sequence-specific DNA binding GO:0044238 (1.00) ! primary metabolic process; GO:0044237 (1.00) ! cellular metabolic process; GO:0043170 (1.00) ! macromolecule metabolic process; GO:0019538 (0.94) ! protein metabolic process; GO:0044260 (0.58) ! cellular macromolecule metabolic process; GO:0034641 (0.53) ! cellular nitrogen compound metabolic process; GO:0006464 (0.51) ! cellular protein modification process; GO:0042787 (0.49) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1901564 (0.47) ! organonitrogen compound metabolic process; GO:0043603 (0.47) ! cellular amide metabolic process; GO:0016485 (0.44) ! protein processing; GO:0006518 (0.44) ! peptide metabolic process; GO:1901360 (0.10) ! organic cyclic compound metabolic process; GO:0046483 (0.10) ! heterocycle metabolic process; GO:0042592 (0.10) ! homeostatic process; GO:0006996 (0.10) ! organelle organization; GO:0006725 (0.10) ! cellular aromatic compound metabolic process; GO:0030435 (0.09) ! sporulation resulting in formation of a cellular spore; GO:0009405 (0.09) ! pathogenesis; GO:0031627 (0.06) ! telomeric loop formation; GO:0097011 (0.05) ! cellular response to granulocyte macrophage colony-stimulating factor stimulus; GO:0071407 (0.05) ! cellular response to organic cyclic compound; GO:0070668 (0.05) ! positive regulation of mast cell proliferation; GO:0061180 (0.05) ! mammary gland epithelium development; GO:0060742 (0.05) ! epithelial cell differentiation involved in prostate gland development; GO:0060740 (0.05) ! prostate gland epithelium morphogenesis; GO:0060397 (0.05) ! JAK-STAT cascade involved in growth hormone signaling pathway; GO:0060376 (0.05) ! positive regulation of mast cell differentiation; GO:0050729 (0.05) ! positive regulation of inflammatory response; GO:0048541 (0.05) ! Peyer's patch development; GO:0046544 (0.05) ! development of secondary male sexual characteristics; GO:0046543 (0.05) ! development of secondary female sexual characteristics; GO:0046449 (0.05) ! creatinine metabolic process; GO:0045954 (0.05) ! positive regulation of natural killer cell mediated cytotoxicity; GO:0045944 (0.05) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045931 (0.05) ! positive regulation of mitotic cell cycle; GO:0045647 (0.05) ! negative regulation of erythrocyte differentiation; GO:0045588 (0.05) ! positive regulation of gamma-delta T cell differentiation; GO:0045579 (0.05) ! positive regulation of B cell differentiation; GO:0045086 (0.05) ! positive regulation of interleukin-2 biosynthetic process; GO:0043536 (0.05) ! positive regulation of blood vessel endothelial cell migration; GO:0043029 (0.05) ! T cell homeostasis; GO:0042104 (0.05) ! positive regulation of activated T cell proliferation; GO:0040018 (0.05) ! positive regulation of multicellular organism growth; GO:0038161 (0.05) ! prolactin signaling pathway; GO:0035999 (0.05) ! tetrahydrofolate interconversion; GO:0033077 (0.05) ! T cell differentiation in thymus; GO:0033026 (0.05) ! negative regulation of mast cell apoptotic process; GO:0032825 (0.05) ! positive regulation of natural killer cell differentiation; GO:0030856 (0.05) ! regulation of epithelial cell differentiation; GO:0019915 (0.05) ! lipid storage; GO:0019557 (0.05) ! histidine catabolic process to glutamate and formate; GO:0019556 (0.05) ! histidine catabolic process to glutamate and formamide; GO:0019530 (0.05) ! taurine metabolic process; GO:0019218 (0.05) ! regulation of steroid metabolic process; GO:0018108 (0.05) ! peptidyl-tyrosine phosphorylation; GO:0007595 (0.05) ! lactation; GO:0007565 (0.05) ! female pregnancy; GO:0007010 (0.05) ! cytoskeleton organization; GO:0006631 (0.05) ! fatty acid metabolic process; GO:0006600 (0.05) ! creatine metabolic process; GO:0006573 (0.05) ! valine metabolic process; GO:0006549 (0.05) ! isoleucine metabolic process; GO:0006107 (0.05) ! oxaloacetate metabolic process; GO:0006105 (0.05) ! succinate metabolic process; GO:0006103 (0.05) ! 2-oxoglutarate metabolic process; GO:0006101 (0.05) ! citrate metabolic process; GO:0001938 (0.05) ! positive regulation of endothelial cell proliferation; GO:0001553 (0.05) ! luteinization; GO:0000255 (0.05) ! allantoin metabolic process GO:0044464 (1.00) ! cell part; GO:0044424 (0.90) ! intracellular part; GO:0043231 (0.88) ! intracellular membrane-bounded organelle; GO:0005737 (0.88) ! cytoplasm; GO:0005634 (0.81) ! nucleus; GO:0005829 (0.76) ! cytosol; GO:0044446 (0.65) ! intracellular organelle part; GO:0044428 (0.54) ! nuclear part; GO:0016020 (0.51) ! membrane; GO:0005654 (0.51) ! nucleoplasm; GO:0044421 (0.48) ! extracellular region part; GO:0044454 (0.45) ! nuclear chromosome part; GO:0032991 (0.45) ! macromolecular complex; GO:0005615 (0.44) ! extracellular space; GO:0000790 (0.41) ! nuclear chromatin; GO:0044425 (0.31) ! membrane part; GO:0031090 (0.23) ! organelle membrane; GO:0005886 (0.23) ! plasma membrane; GO:0090575 (0.15) ! RNA polymerase II transcription factor complex; GO:0045121 (0.15) ! membrane raft; GO:0043232 (0.15) ! intracellular non-membrane-bounded organelle; GO:0005743 (0.15) ! mitochondrial inner membrane; GO:0005739 (0.15) ! mitochondrion; GO:0070062 (0.07) ! extracellular exosome; GO:0048471 (0.07) ! perinuclear region of cytoplasm; GO:0030868 (0.07) ! smooth endoplasmic reticulum membrane; GO:0030425 (0.07) ! dendrite; GO:0030424 (0.07) ! axon; GO:0016021 (0.07) ! integral component of membrane; GO:0005913 (0.07) ! cell-cell adherens junction; GO:0005856 (0.07) ! cytoskeleton; GO:0005814 (0.07) ! centriole; GO:0005794 (0.07) ! Golgi apparatus; GO:0005793 (0.07) ! endoplasmic reticulum-Golgi intermediate compartment; GO:0005783 (0.07) ! endoplasmic reticulum; GO:0005730 (0.07) ! nucleolus; GO:0000139 (0.07) ! Golgi membrane; GO:0000783 (0.06) ! nuclear telomere cap complex 2 43780435-43787612 (17q21.31) High: testis (cells in seminiferous ducts); Testis: 36.54; Brain - Cerebellar Hemisphere: 0.30; Brain - Cerebellum: 0.28; Spleen: 0.12; Brain - Frontal Cortex (BA9): 0.09; Brain - Cortex: 0.08; Nerve - Tibial: 0.06; Artery - Coronary: 0.06; Artery - Aorta: 0.06; Pituitary: 0.06; Brain - Hypothalamus: 0.06; Brain - Anterior cingulate cortex (BA24): 0.05; Skin - Sun Exposed (Lower leg): 0.05; Cervix - Ectocervix: 0.05; Brain - Nucleus accumbens (basal ganglia): 0.05; Brain - Spinal cord (cervical c-1): 0.05; Adipose - Subcutaneous: 0.05; Brain - Substantia nigra: 0.05; Brain - Amygdala: 0.05; Lung: 0.04; Breast - Mammary Tissue: 0.04; Thyroid: 0.04; Artery - Tibial: 0.04; Cervix - Endocervix: 0.04; Bladder: 0.04; Brain - Hippocampus: 0.04; Fallopian Tube: 0.04; Brain - Caudate (basal ganglia): 0.04; Cells - Transformed fibroblasts: 0.03; Brain - Putamen (basal ganglia): 0.03; Uterus: 0.03; Skin - Not Sun Exposed (Suprapubic): 0.03; Prostate: 0.03; Colon - Sigmoid: 0.03; Adrenal Gland: 0.03; Muscle - Skeletal: 0.03; Adipose - Visceral (Omentum): 0.02; Esophagus - Gastroesophageal Junction: 0.02; Esophagus - Muscularis: 0.02; Vagina: 0.02; Liver: 0.02; Minor Salivary Gland: 0.02; Small Intestine - Terminal Ileum: 0.02; Whole Blood: 0.02; Kidney - Cortex: 0.02; Cells - EBV-transformed lymphocytes: 0.02; Ovary: 0.02; Stomach: 0.02; Esophagus - Mucosa: 0.01; Heart - Atrial Appendage: 0.01; Colon - Transverse: 0.01; Heart - Left Ventricle: 0.01; MNNSLDYLAYPVIVSNHRQSTTFRKKLDFGHYVSHKNRIQIAKPTVDTKPPVAHTNHILKLSKLQGEQKKINKIEYENKQLCQKIANAHRGPAKVDCWNEYFSKSLNRETRNRELVRITMENQGILKRLVDRKPHYDRRASEIDWQNSRRYIRNTTRYLLSQNE LSM12 Protein LSM12 homolog LSM12_HUMAN (Q3MHD2-1) GO:0003723 (0.59) ! RNA binding; GO:0003729 (0.13) ! mRNA binding; GO:0046872 (0.11) ! metal ion binding; GO:0008810 (0.06) ! cellulase activity GO:0009987 (1.00) ! cellular process; GO:0044238 (0.80) ! primary metabolic process; GO:0044237 (0.80) ! cellular metabolic process; GO:0043170 (0.80) ! macromolecule metabolic process; GO:0090304 (0.79) ! nucleic acid metabolic process; GO:0044260 (0.74) ! cellular macromolecule metabolic process; GO:0016070 (0.73) ! RNA metabolic process; GO:0022618 (0.39) ! ribonucleoprotein complex assembly; GO:0000387 (0.32) ! spliceosomal snRNP assembly; GO:0051170 (0.11) ! nuclear import; GO:0000398 (0.11) ! mRNA splicing, via spliceosome; GO:0033962 (0.07) ! cytoplasmic mRNA processing body assembly; GO:0031087 (0.07) ! deadenylation-independent decapping of nuclear-transcribed mRNA; GO:0030245 (0.05) ! cellulose catabolic process GO:0044424 (1.00) ! intracellular part; GO:0044444 (0.75) ! cytoplasmic part; GO:0043229 (0.64) ! intracellular organelle; GO:0032991 (0.60) ! macromolecular complex; GO:0005576 (0.55) ! extracellular region; GO:0005829 (0.47) ! cytosol; GO:0005634 (0.33) ! nucleus; GO:0036464 (0.31) ! cytoplasmic ribonucleoprotein granule; GO:0034719 (0.29) ! SMN-Sm protein complex; GO:0032797 (0.29) ! SMN complex; GO:0044422 (0.26) ! organelle part; GO:0005737 (0.26) ! cytoplasm; GO:0010494 (0.25) ! cytoplasmic stress granule; GO:0005840 (0.25) ! ribosome; GO:0016604 (0.19) ! nuclear body; GO:0005654 (0.19) ! nucleoplasm; GO:0055120 (0.07) ! striated muscle dense body; GO:0000932 (0.06) ! cytoplasmic mRNA processing body 3 44034635-44067619 (17q21.31) High: stomach 2 (glandular cells);stomach 1 (glandular cells);seminal vesicle (glandular cells);colon (endothelial cells; glandular cells; peripheral nerve/ganglion);gallbladder (glandular cells);esophagus (squamous epithelial cells);kidney (cells in tubules);testis (cells in seminiferous ducts);tonsil (germinal center cells; non-germinal center cells; squamous epithelial cells);breast (glandular cells);epididymis (glandular cells);adrenal gland (glandular cells);thyroid gland (glandular cells);cerebral cortex (neuronal cells);lymph node (germinal center cells; non-germinal center cells);bronchus (respiratory epithelial cells);skeletal muscle (myocytes);urinary bladder (urothelial cells);small intestine (glandular cells);liver (hepatocytes);rectum (glandular cells);cervix, uterine (glandular cells);duodenum (glandular cells);cerebellum (cells in molecular layer; Purkinje cells);appendix (glandular cells; lymphoid tissue);nasopharynx (respiratory epithelial cells);oral mucosa (squamous epithelial cells);skin 2 (epidermal cells);Medium: cerebellum (cells in granular layer);placenta (decidual cells; trophoblastic cells);testis (Leydig cells);caudate (neuronal cells);fallopian tube (glandular cells);prostate (glandular cells);vagina (squamous epithelial cells);endometrium 1 (glandular cells);endometrium 2 (glandular cells);salivary gland (glandular cells);lung (macrophages; pneumocytes);heart muscle (myocytes);ovary (follicle cells);skin 1 (fibroblasts; keratinocytes; Langerhans; melanocytes);cerebral cortex (endothelial cells);kidney (cells in glomeruli);pancreas (exocrine glandular cells; islets of Langerhans);Low: spleen (cells in white pulp);bone marrow (hematopoietic cells);parathyroid gland (glandular cells);endometrium 1 (cells in endometrial stroma);liver (bile duct cells);smooth muscle (smooth muscle cells);ovary (ovarian stroma cells);cerebral cortex (glial cells; neuropil);cervix, uterine (squamous epithelial cells);breast (myoepithelial cells); Cells - EBV-transformed lymphocytes: 16.88; Cells - Transformed fibroblasts: 16.69; Testis: 13.62; Esophagus - Mucosa: 7.91; Uterus: 7.03; Lung: 6.80; Fallopian Tube: 6.73; Vagina: 6.67; Bladder: 6.56; Cervix - Ectocervix: 6.50; Cervix - Endocervix: 6.42; Brain - Cerebellar Hemisphere: 6.34; Adipose - Visceral (Omentum): 6.34; Thyroid: 6.29; Adrenal Gland: 6.21; Breast - Mammary Tissue: 6.11; Ovary: 5.97; Adipose - Subcutaneous: 5.96; Esophagus - Muscularis: 5.96; Prostate: 5.93; Colon - Sigmoid: 5.91; Artery - Coronary: 5.88; Artery - Aorta: 5.87; Artery - Tibial: 5.85; Spleen: 5.68; Esophagus - Gastroesophageal Junction: 5.62; Nerve - Tibial: 5.58; Muscle - Skeletal: 5.54; Minor Salivary Gland: 5.49; Colon - Transverse: 5.46; Brain - Spinal cord (cervical c-1): 5.25; Brain - Cerebellum: 5.07; Small Intestine - Terminal Ileum: 5.05; Skin - Sun Exposed (Lower leg): 5.04; Skin - Not Sun Exposed (Suprapubic): 5.00; Brain - Frontal Cortex (BA9): 4.97; Pituitary: 4.89; Stomach: 4.69; Whole Blood: 4.65; Brain - Hypothalamus: 4.58; Brain - Anterior cingulate cortex (BA24): 3.88; Heart - Atrial Appendage: 3.80; Kidney - Cortex: 3.61; Brain - Substantia nigra: 3.55; Brain - Cortex: 3.50; Liver: 3.46; Brain - Nucleus accumbens (basal ganglia): 3.44; Pancreas: 3.33; Brain - Amygdala: 3.29; Brain - Hippocampus: 3.14; Brain - Caudate (basal ganglia): 3.04; Heart - Left Ventricle: 2.72; Brain - Putamen (basal ganglia): 2.44; MAAPPGEYFSVGSQVSCRTCQEQRLQGEVVAFDYQSKMLALKCPSSSGKPNHADILLINLQYVSEVEIINDRTETPPPLASLNVSKLASKARTEKEEKLSQAYAISAGVSLEGQQLFQTIHKTIKDCKWQEKNIVVMEEVVITPPYQVENCKGKEGSALSHVRKIVEKHFRDVESQKILQRSQAQQPQKEAALSS C17orf53 Uncharacterized protein C17orf53 CQ053_HUMAN (Q8N3J3-1) GO:0003824 (0.54) ! catalytic activity; GO:0016787 (0.43) ! hydrolase activity; GO:0004175 (0.37) ! endopeptidase activity; GO:0004252 (0.36) ! serine-type endopeptidase activity; GO:1901363 (0.18) ! heterocyclic compound binding; GO:0097159 (0.18) ! organic cyclic compound binding; GO:0016740 (0.17) ! transferase activity; GO:0003676 (0.16) ! nucleic acid binding; GO:0016772 (0.12) ! transferase activity, transferring phosphorus-containing groups; GO:0005215 (0.11) ! transporter activity; GO:0015075 (0.09) ! ion transmembrane transporter activity; GO:0004672 (0.09) ! protein kinase activity; GO:0003723 (0.09) ! RNA binding; GO:0019899 (0.08) ! enzyme binding; GO:0005261 (0.08) ! cation channel activity; GO:0046873 (0.07) ! metal ion transmembrane transporter activity; GO:0044877 (0.07) ! macromolecular complex binding; GO:0022836 (0.07) ! gated channel activity; GO:0008092 (0.07) ! cytoskeletal protein binding; GO:0004674 (0.07) ! protein serine/threonine kinase activity; GO:0000989 (0.07) ! transcription factor activity, transcription factor binding; GO:0098772 (0.06) ! molecular function regulator; GO:0022843 (0.06) ! voltage-gated cation channel activity; GO:0005198 (0.06) ! structural molecule activity; GO:0003712 (0.06) ! transcription cofactor activity; GO:0003677 (0.06) ! DNA binding; GO:0044822 (0.05) ! poly(A) RNA binding; GO:0016788 (0.05) ! hydrolase activity, acting on ester bonds; GO:0015085 (0.05) ! calcium ion transmembrane transporter activity; GO:0001076 (0.05) ! transcription factor activity, RNA polymerase II transcription factor binding; GO:0044212 (0.04) ! transcription regulatory region DNA binding; GO:0032403 (0.04) ! protein complex binding; GO:0030234 (0.04) ! enzyme regulator activity; GO:0016887 (0.04) ! ATPase activity; GO:0005245 (0.04) ! voltage-gated calcium channel activity; GO:0005102 (0.04) ! receptor binding; GO:0004871 (0.04) ! signal transducer activity; GO:0004842 (0.04) ! ubiquitin-protein transferase activity; GO:0003779 (0.04) ! actin binding; GO:0003700 (0.04) ! transcription factor activity, sequence-specific DNA binding; GO:0003682 (0.04) ! chromatin binding; GO:0001104 (0.04) ! RNA polymerase II transcription cofactor activity; GO:0097367 (0.03) ! carbohydrate derivative binding; GO:0043565 (0.03) ! sequence-specific DNA binding; GO:0031267 (0.03) ! small GTPase binding; GO:0016779 (0.03) ! nucleotidyltransferase activity; GO:0015079 (0.03) ! potassium ion transmembrane transporter activity; GO:0008134 (0.03) ! transcription factor binding; GO:0008017 (0.03) ! microtubule binding; GO:0005543 (0.03) ! phospholipid binding; GO:0005201 (0.03) ! extracellular matrix structural constituent; GO:0003713 (0.03) ! transcription coactivator activity; GO:0099600 (0.02) ! transmembrane receptor activity; GO:0046872 (0.02) ! metal ion binding; GO:0035639 (0.02) ! purine ribonucleoside triphosphate binding; GO:0035091 (0.02) ! phosphatidylinositol binding; GO:0032555 (0.02) ! purine ribonucleotide binding; GO:0032550 (0.02) ! purine ribonucleoside binding; GO:0019904 (0.02) ! protein domain specific binding; GO:0019901 (0.02) ! protein kinase binding; GO:0017016 (0.02) ! Ras GTPase binding; GO:0016791 (0.02) ! phosphatase activity; GO:0008331 (0.02) ! high voltage-gated calcium channel activity; GO:0008094 (0.02) ! DNA-dependent ATPase activity; GO:0005487 (0.02) ! nucleocytoplasmic transporter activity; GO:0005249 (0.02) ! voltage-gated potassium channel activity; GO:0005096 (0.02) ! GTPase activator activity; GO:0005085 (0.02) ! guanyl-nucleotide exchange factor activity; GO:0004702 (0.02) ! receptor signaling protein serine/threonine kinase activity; GO:0003690 (0.02) ! double-stranded DNA binding; GO:0002039 (0.02) ! p53 binding; GO:0001190 (0.02) ! transcriptional activator activity, RNA polymerase II transcription factor binding; GO:0001055 (0.02) ! RNA polymerase II activity; GO:0097493 (0.01) ! structural molecule activity conferring elasticity; GO:0097110 (0.01) ! scaffold protein binding; GO:0061630 (0.01) ! ubiquitin protein ligase activity; GO:0052689 (0.01) ! carboxylic ester hydrolase activity; GO:0051371 (0.01) ! muscle alpha-actinin binding; GO:0051015 (0.01) ! actin filament binding; GO:0050839 (0.01) ! cell adhesion molecule binding; GO:0047485 (0.01) ! protein N-terminus binding; GO:0045295 (0.01) ! gamma-catenin binding; GO:0043175 (0.01) ! RNA polymerase core enzyme binding; GO:0042803 (0.01) ! protein homodimerization activity; GO:0042800 (0.01) ! histone methyltransferase activity (H3-K4 specific); GO:0042393 (0.01) ! histone binding; GO:0035612 (0.01) ! AP-2 adaptor complex binding; GO:0035257 (0.01) ! nuclear hormone receptor binding; GO:0034596 (0.01) ! phosphatidylinositol phosphate 4-phosphatase activity; GO:0034595 (0.01) ! phosphatidylinositol phosphate 5-phosphatase activity; GO:0031491 (0.01) ! nucleosome binding; GO:0030507 (0.01) ! spectrin binding; GO:0030374 (0.01) ! ligand-dependent nuclear receptor transcription coactivator activity; GO:0019905 (0.01) ! syntaxin binding; GO:0019902 (0.01) ! phosphatase binding; GO:0019887 (0.01) ! protein kinase regulator activity; GO:0017137 (0.01) ! Rab GTPase binding; GO:0017124 (0.01) ! SH3 domain binding; GO:0017056 (0.01) ! structural constituent of nuclear pore; GO:0017049 (0.01) ! GTP-Rho binding; GO:0016922 (0.01) ! ligand-dependent nuclear receptor binding; GO:0016491 (0.01) ! oxidoreductase activity; GO:0016247 (0.01) ! channel regulator activity; GO:0008332 (0.01) ! low voltage-gated calcium channel activity; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008234 (0.01) ! cysteine-type peptidase activity; GO:0008201 (0.01) ! heparin binding; GO:0008190 (0.01) ! eukaryotic initiation factor 4E binding; GO:0008139 (0.01) ! nuclear localization sequence binding; GO:0008093 (0.01) ! cytoskeletal adaptor activity; GO:0008026 (0.01) ! ATP-dependent helicase activity; GO:0008022 (0.01) ! protein C-terminus binding; GO:0008013 (0.01) ! beta-catenin binding; GO:0005546 (0.01) ! phosphatidylinositol-4,5-bisphosphate binding; GO:0005544 (0.01) ! calcium-dependent phospholipid binding; GO:0005540 (0.01) ! hyaluronic acid binding; GO:0005524 (0.01) ! ATP binding; GO:0005518 (0.01) ! collagen binding; GO:0005516 (0.01) ! calmodulin binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0004888 (0.01) ! transmembrane signaling receptor activity; GO:0004857 (0.01) ! enzyme inhibitor activity; GO:0004725 (0.01) ! protein tyrosine phosphatase activity; GO:0004715 (0.01) ! non-membrane spanning protein tyrosine kinase activity; GO:0004620 (0.01) ! phospholipase activity; GO:0004540 (0.01) ! ribonuclease activity; GO:0004407 (0.01) ! histone deacetylase activity; GO:0004402 (0.01) ! histone acetyltransferase activity; GO:0003964 (0.01) ! RNA-directed DNA polymerase activity; GO:0003887 (0.01) ! DNA-directed DNA polymerase activity; GO:0003777 (0.01) ! microtubule motor activity; GO:0003729 (0.01) ! mRNA binding; GO:0003684 (0.01) ! damaged DNA binding; GO:0003678 (0.01) ! DNA helicase activity; GO:0001106 (0.01) ! RNA polymerase II transcription corepressor activity; GO:0001105 (0.01) ! RNA polymerase II transcription coactivator activity; GO:0001085 (0.01) ! RNA polymerase II transcription factor binding; GO:0001047 (0.01) ! core promoter binding; GO:0000981 (0.01) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0000978 (0.01) ! RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0009987 (0.80) ! cellular process; GO:0065007 (0.75) ! biological regulation; GO:0050789 (0.72) ! regulation of biological process; GO:0044699 (0.71) ! single-organism process; GO:0050794 (0.70) ! regulation of cellular process; GO:0044763 (0.67) ! single-organism cellular process; GO:0071704 (0.62) ! organic substance metabolic process; GO:0044237 (0.62) ! cellular metabolic process; GO:0016043 (0.62) ! cellular component organization; GO:0044260 (0.61) ! cellular macromolecule metabolic process; GO:0048518 (0.60) ! positive regulation of biological process; GO:0051179 (0.58) ! localization; GO:0048519 (0.58) ! negative regulation of biological process; GO:0065008 (0.57) ! regulation of biological quality; GO:0048523 (0.57) ! negative regulation of cellular process; GO:0006810 (0.57) ! transport; GO:0051239 (0.54) ! regulation of multicellular organismal process; GO:0048583 (0.54) ! regulation of response to stimulus; GO:1902578 (0.53) ! single-organism localization; GO:0048584 (0.52) ! positive regulation of response to stimulus; GO:0044765 (0.52) ! single-organism transport; GO:0044238 (0.52) ! primary metabolic process; GO:0016192 (0.52) ! vesicle-mediated transport; GO:0051240 (0.51) ! positive regulation of multicellular organismal process; GO:0042127 (0.51) ! regulation of cell proliferation; GO:0080134 (0.50) ! regulation of response to stress; GO:0032101 (0.50) ! regulation of response to external stimulus; GO:0030198 (0.50) ! extracellular matrix organization; GO:0022411 (0.50) ! cellular component disassembly; GO:0022407 (0.50) ! regulation of cell-cell adhesion; GO:0010810 (0.50) ! regulation of cell-substrate adhesion; GO:0007162 (0.50) ! negative regulation of cell adhesion; GO:0006887 (0.50) ! exocytosis; GO:2000047 (0.49) ! regulation of cell-cell adhesion mediated by cadherin; GO:0045055 (0.49) ! regulated exocytosis; GO:0032103 (0.49) ! positive regulation of response to external stimulus; GO:0030194 (0.49) ! positive regulation of blood coagulation; GO:0022408 (0.49) ! negative regulation of cell-cell adhesion; GO:0019538 (0.45) ! protein metabolic process; GO:0006508 (0.37) ! proteolysis; GO:0048585 (0.31) ! negative regulation of response to stimulus; GO:0051241 (0.30) ! negative regulation of multicellular organismal process; GO:0051919 (0.29) ! positive regulation of fibrinolysis; GO:0032502 (0.19) ! developmental process; GO:0044767 (0.18) ! single-organism developmental process; GO:0019222 (0.18) ! regulation of metabolic process; GO:0080090 (0.17) ! regulation of primary metabolic process; GO:0060255 (0.17) ! regulation of macromolecule metabolic process; GO:0031323 (0.17) ! regulation of cellular metabolic process; GO:0048522 (0.16) ! positive regulation of cellular process; GO:0050896 (0.15) ! response to stimulus; GO:0051171 (0.14) ! regulation of nitrogen compound metabolic process; GO:0048856 (0.14) ! anatomical structure development; GO:0032501 (0.14) ! multicellular organismal process; GO:0007165 (0.14) ! signal transduction; GO:0051128 (0.13) ! regulation of cellular component organization; GO:0044267 (0.13) ! cellular protein metabolic process; GO:0031326 (0.13) ! regulation of cellular biosynthetic process; GO:0019219 (0.13) ! regulation of nucleobase-containing compound metabolic process; GO:0010468 (0.13) ! regulation of gene expression; GO:0006996 (0.13) ! organelle organization; GO:2000112 (0.12) ! regulation of cellular macromolecule biosynthetic process; GO:0051252 (0.12) ! regulation of RNA metabolic process; GO:0048869 (0.12) ! cellular developmental process; GO:0006464 (0.12) ! cellular protein modification process; GO:0090304 (0.11) ! nucleic acid metabolic process; GO:0044707 (0.11) ! single-multicellular organism process; GO:0006355 (0.11) ! regulation of transcription, DNA-templated; GO:0051641 (0.10) ! cellular localization; GO:0043933 (0.10) ! macromolecular complex subunit organization; GO:0032879 (0.10) ! regulation of localization; GO:0006950 (0.10) ! response to stress; GO:0051649 (0.09) ! establishment of localization in cell; GO:0022607 (0.09) ! cellular component assembly; GO:0009653 (0.09) ! anatomical structure morphogenesis; GO:0006357 (0.09) ! regulation of transcription from RNA polymerase II promoter; GO:0051049 (0.08) ! regulation of transport; GO:0050793 (0.08) ! regulation of developmental process; GO:0031325 (0.08) ! positive regulation of cellular metabolic process; GO:0031324 (0.08) ! negative regulation of cellular metabolic process; GO:0023051 (0.08) ! regulation of signaling; GO:0016070 (0.08) ! RNA metabolic process; GO:0010646 (0.08) ! regulation of cell communication; GO:0010605 (0.08) ! negative regulation of macromolecule metabolic process; GO:0010604 (0.08) ! positive regulation of macromolecule metabolic process; GO:2000026 (0.07) ! regulation of multicellular organismal development; GO:1902589 (0.07) ! single-organism organelle organization; GO:0065009 (0.07) ! regulation of molecular function; GO:0033043 (0.07) ! regulation of organelle organization; GO:0009966 (0.07) ! regulation of signal transduction; GO:0007010 (0.07) ! cytoskeleton organization; GO:0006928 (0.07) ! movement of cell or subcellular component; GO:0006796 (0.07) ! phosphate-containing compound metabolic process; GO:2000113 (0.06) ! negative regulation of cellular macromolecule biosynthetic process; GO:0051716 (0.06) ! cellular response to stimulus; GO:0051253 (0.06) ! negative regulation of RNA metabolic process; GO:0046907 (0.06) ! intracellular transport; GO:0045935 (0.06) ! positive regulation of nucleobase-containing compound metabolic process; GO:0045595 (0.06) ! regulation of cell differentiation; GO:0044700 (0.06) ! single organism signaling; GO:0042391 (0.06) ! regulation of membrane potential; GO:0035556 (0.06) ! intracellular signal transduction; GO:0010629 (0.06) ! negative regulation of gene expression; GO:0008104 (0.06) ! protein localization; GO:0007154 (0.06) ! cell communication; GO:0007017 (0.06) ! microtubule-based process; GO:0006468 (0.06) ! protein phosphorylation; GO:0002376 (0.06) ! immune system process; GO:1901576 (0.05) ! organic substance biosynthetic process; GO:0071822 (0.05) ! protein complex subunit organization; GO:0065003 (0.05) ! macromolecular complex assembly; GO:0060284 (0.05) ! regulation of cell development; GO:0051960 (0.05) ! regulation of nervous system development; GO:0051246 (0.05) ! regulation of protein metabolic process; GO:0050790 (0.05) ! regulation of catalytic activity; GO:0048513 (0.05) ! animal organ development; GO:0045893 (0.05) ! positive regulation of transcription, DNA-templated; GO:0045892 (0.05) ! negative regulation of transcription, DNA-templated; GO:0044249 (0.05) ! cellular biosynthetic process; GO:0044093 (0.05) ! positive regulation of molecular function; GO:0044087 (0.05) ! regulation of cellular component biogenesis; GO:0042221 (0.05) ! response to chemical; GO:0040011 (0.05) ! locomotion; GO:0033554 (0.05) ! cellular response to stress; GO:0030154 (0.05) ! cell differentiation; GO:0030030 (0.05) ! cell projection organization; GO:0022603 (0.05) ! regulation of anatomical structure morphogenesis; GO:0022414 (0.05) ! reproductive process; GO:0022402 (0.05) ! cell cycle process; GO:0016071 (0.05) ! mRNA metabolic process; GO:0007267 (0.05) ! cell-cell signaling; GO:0007166 (0.05) ! cell surface receptor signaling pathway; GO:0006952 (0.05) ! defense response; GO:0006325 (0.05) ! chromatin organization; GO:0003008 (0.05) ! system process; GO:1903047 (0.04) ! mitotic cell cycle process; GO:1902531 (0.04) ! regulation of intracellular signal transduction; GO:0060627 (0.04) ! regulation of vesicle-mediated transport; GO:0051726 (0.04) ! regulation of cell cycle; GO:0051493 (0.04) ! regulation of cytoskeleton organization; GO:0051130 (0.04) ! positive regulation of cellular component organization; GO:0051129 (0.04) ! negative regulation of cellular component organization; GO:0051094 (0.04) ! positive regulation of developmental process; GO:0051050 (0.04) ! positive regulation of transport; GO:0048731 (0.04) ! system development; GO:0048646 (0.04) ! anatomical structure formation involved in morphogenesis; GO:0045944 (0.04) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045664 (0.04) ! regulation of neuron differentiation; GO:0044710 (0.04) ! single-organism metabolic process; GO:0044702 (0.04) ! single organism reproductive process; GO:0040008 (0.04) ! regulation of growth; GO:0034622 (0.04) ! cellular macromolecular complex assembly; GO:0034613 (0.04) ! cellular protein localization; GO:0032989 (0.04) ! cellular component morphogenesis; GO:0032268 (0.04) ! regulation of cellular protein metabolic process; GO:0022604 (0.04) ! regulation of cell morphogenesis; GO:0018193 (0.04) ! peptidyl-amino acid modification; GO:0016477 (0.04) ! cell migration; GO:0010941 (0.04) ! regulation of cell death; GO:0009967 (0.04) ! positive regulation of signal transduction; GO:0009059 (0.04) ! macromolecule biosynthetic process; GO:0006955 (0.04) ! immune response; GO:0006812 (0.04) ! cation transport; GO:0000226 (0.04) ! microtubule cytoskeleton organization; GO:0000122 (0.04) ! negative regulation of transcription from RNA polymerase II promoter; GO:2000021 (0.03) ! regulation of ion homeostasis; GO:1903530 (0.03) ! regulation of secretion by cell; GO:1902580 (0.03) ! single-organism cellular localization; GO:0086010 (0.03) ! membrane depolarization during action potential; GO:0070925 (0.03) ! organelle assembly; GO:0070887 (0.03) ! cellular response to chemical stimulus; GO:0070507 (0.03) ! regulation of microtubule cytoskeleton organization; GO:0051704 (0.03) ! multi-organism process; GO:0051336 (0.03) ! regulation of hydrolase activity; GO:0051247 (0.03) ! positive regulation of protein metabolic process; GO:0050877 (0.03) ! neurological system process; GO:0048858 (0.03) ! cell projection morphogenesis; GO:0048638 (0.03) ! regulation of developmental growth; GO:0048589 (0.03) ! developmental growth; GO:0048468 (0.03) ! cell development; GO:0045927 (0.03) ! positive regulation of growth; GO:0045087 (0.03) ! innate immune response; GO:0044248 (0.03) ! cellular catabolic process; GO:0043085 (0.03) ! positive regulation of catalytic activity; GO:0042981 (0.03) ! regulation of apoptotic process; GO:0042592 (0.03) ! homeostatic process; GO:0034645 (0.03) ! cellular macromolecule biosynthetic process; GO:0033365 (0.03) ! protein localization to organelle; GO:0032774 (0.03) ! RNA biosynthetic process; GO:0032446 (0.03) ! protein modification by small protein conjugation; GO:0030036 (0.03) ! actin cytoskeleton organization; GO:0010975 (0.03) ! regulation of neuron projection development; GO:0010769 (0.03) ! regulation of cell morphogenesis involved in differentiation; GO:0010720 (0.03) ! positive regulation of cell development; GO:0010639 (0.03) ! negative regulation of organelle organization; GO:0010564 (0.03) ! regulation of cell cycle process; GO:0010033 (0.03) ! response to organic substance; GO:0009968 (0.03) ! negative regulation of signal transduction; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0009605 (0.03) ! response to external stimulus; GO:0009057 (0.03) ! macromolecule catabolic process; GO:0007610 (0.03) ! behavior; GO:0007475 (0.03) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.03) ! open tracheal system development; GO:0007275 (0.03) ! multicellular organism development; GO:0007268 (0.03) ! chemical synaptic transmission; GO:0006897 (0.03) ! endocytosis; GO:0006886 (0.03) ! intracellular protein transport; GO:0006816 (0.03) ! calcium ion transport; GO:0006461 (0.03) ! protein complex assembly; GO:0006397 (0.03) ! mRNA processing; GO:0006259 (0.03) ! DNA metabolic process; GO:0001932 (0.03) ! regulation of protein phosphorylation; GO:0001558 (0.03) ! regulation of cell growth; GO:1903305 (0.02) ! regulation of regulated secretory pathway; GO:1902582 (0.02) ! single-organism intracellular transport; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:1901990 (0.02) ! regulation of mitotic cell cycle phase transition; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:0090305 (0.02) ! nucleic acid phosphodiester bond hydrolysis; GO:0090066 (0.02) ! regulation of anatomical structure size; GO:0080135 (0.02) ! regulation of cellular response to stress; GO:0071310 (0.02) ! cellular response to organic substance; GO:0070509 (0.02) ! calcium ion import; GO:0060548 (0.02) ! negative regulation of cell death; GO:0060341 (0.02) ! regulation of cellular localization; GO:0051707 (0.02) ! response to other organism; GO:0051270 (0.02) ! regulation of cellular component movement; GO:0051223 (0.02) ! regulation of protein transport; GO:0051093 (0.02) ! negative regulation of developmental process; GO:0050890 (0.02) ! cognition; GO:0050772 (0.02) ! positive regulation of axonogenesis; GO:0048878 (0.02) ! chemical homeostasis; GO:0048813 (0.02) ! dendrite morphogenesis; GO:0048729 (0.02) ! tissue morphogenesis; GO:0048639 (0.02) ! positive regulation of developmental growth; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0048193 (0.02) ! Golgi vesicle transport; GO:0046777 (0.02) ! protein autophosphorylation; GO:0045930 (0.02) ! negative regulation of mitotic cell cycle; GO:0045859 (0.02) ! regulation of protein kinase activity; GO:0044802 (0.02) ! single-organism membrane organization; GO:0044708 (0.02) ! single-organism behavior; GO:0044265 (0.02) ! cellular macromolecule catabolic process; GO:0044089 (0.02) ! positive regulation of cellular component biogenesis; GO:0043087 (0.02) ! regulation of GTPase activity; GO:0043009 (0.02) ! chordate embryonic development; GO:0042787 (0.02) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0035239 (0.02) ! tube morphogenesis; GO:0035148 (0.02) ! tube formation; GO:0034728 (0.02) ! nucleosome organization; GO:0034220 (0.02) ! ion transmembrane transport; GO:0032984 (0.02) ! macromolecular complex disassembly; GO:0032414 (0.02) ! positive regulation of ion transmembrane transporter activity; GO:0032269 (0.02) ! negative regulation of cellular protein metabolic process; GO:0030522 (0.02) ! intracellular receptor signaling pathway; GO:0030516 (0.02) ! regulation of axon extension; GO:0030307 (0.02) ! positive regulation of cell growth; GO:0022618 (0.02) ! ribonucleoprotein complex assembly; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0022404 (0.02) ! molting cycle process; GO:0019725 (0.02) ! cellular homeostasis; GO:0018205 (0.02) ! peptidyl-lysine modification; GO:0016570 (0.02) ! histone modification; GO:0016049 (0.02) ! cell growth; GO:0010948 (0.02) ! negative regulation of cell cycle process; GO:0010942 (0.02) ! positive regulation of cell death; GO:0010035 (0.02) ! response to inorganic substance; GO:0009888 (0.02) ! tissue development; GO:0009887 (0.02) ! organ morphogenesis; GO:0009755 (0.02) ! hormone-mediated signaling pathway; GO:0009719 (0.02) ! response to endogenous stimulus; GO:0008016 (0.02) ! regulation of heart contraction; GO:0007423 (0.02) ! sensory organ development; GO:0007409 (0.02) ! axonogenesis; GO:0007169 (0.02) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007155 (0.02) ! cell adhesion; GO:0007026 (0.02) ! negative regulation of microtubule depolymerization; GO:0007018 (0.02) ! microtubule-based movement; GO:0006913 (0.02) ! nucleocytoplasmic transport; GO:0006898 (0.02) ! receptor-mediated endocytosis; GO:0006629 (0.02) ! lipid metabolic process; GO:0006351 (0.02) ! transcription, DNA-templated; GO:0006338 (0.02) ! chromatin remodeling; GO:0006281 (0.02) ! DNA repair; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0003002 (0.02) ! regionalization; GO:0002682 (0.02) ! regulation of immune system process; GO:0001934 (0.02) ! positive regulation of protein phosphorylation; GO:0001709 (0.02) ! cell fate determination; GO:0001578 (0.02) ! microtubule bundle formation; GO:0000398 (0.02) ! mRNA splicing, via spliceosome; GO:2000651 (0.01) ! positive regulation of sodium ion transmembrane transporter activity; GO:2000369 (0.01) ! regulation of clathrin-mediated endocytosis; GO:2000045 (0.01) ! regulation of G1/S transition of mitotic cell cycle; GO:1990778 (0.01) ! protein localization to cell periphery; GO:1904589 (0.01) ! regulation of protein import; GO:1903902 (0.01) ! positive regulation of viral life cycle; GO:1903747 (0.01) ! regulation of establishment of protein localization to mitochondrion; GO:1903706 (0.01) ! regulation of hemopoiesis; GO:1903533 (0.01) ! regulation of protein targeting; GO:1903311 (0.01) ! regulation of mRNA metabolic process; GO:1903115 (0.01) ! regulation of actin filament-based movement; GO:1903046 (0.01) ! meiotic cell cycle process; GO:1902685 (0.01) ! positive regulation of receptor localization to synapse; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1902275 (0.01) ! regulation of chromatin organization; GO:1901615 (0.01) ! organic hydroxy compound metabolic process; GO:1901564 (0.01) ! organonitrogen compound metabolic process; GO:1901214 (0.01) ! regulation of neuron death; GO:1901201 (0.01) ! regulation of extracellular matrix assembly; GO:0098876 (0.01) ! vesicle-mediated transport to the plasma membrane; GO:0098779 (0.01) ! mitophagy in response to mitochondrial depolarization; GO:0097193 (0.01) ! intrinsic apoptotic signaling pathway; GO:0090630 (0.01) ! activation of GTPase activity; GO:0090596 (0.01) ! sensory organ morphogenesis; GO:0090316 (0.01) ! positive regulation of intracellular protein transport; GO:0090287 (0.01) ! regulation of cellular response to growth factor stimulus; GO:0090090 (0.01) ! negative regulation of canonical Wnt signaling pathway; GO:0090068 (0.01) ! positive regulation of cell cycle process; GO:0090002 (0.01) ! establishment of protein localization to plasma membrane; GO:0072319 (0.01) ! vesicle uncoating; GO:0071688 (0.01) ! striated muscle myosin thick filament assembly; GO:0071363 (0.01) ! cellular response to growth factor stimulus; GO:0071300 (0.01) ! cellular response to retinoic acid; GO:0071214 (0.01) ! cellular response to abiotic stimulus; GO:0070588 (0.01) ! calcium ion transmembrane transport; GO:0061512 (0.01) ! protein localization to cilium; GO:0061061 (0.01) ! muscle structure development; GO:0060402 (0.01) ! calcium ion transport into cytosol; GO:0060371 (0.01) ! regulation of atrial cardiac muscle cell membrane depolarization; GO:0060271 (0.01) ! cilium morphogenesis; GO:0060249 (0.01) ! anatomical structure homeostasis; GO:0060047 (0.01) ! heart contraction; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0055117 (0.01) ! regulation of cardiac muscle contraction; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051668 (0.01) ! localization within membrane; GO:0051495 (0.01) ! positive regulation of cytoskeleton organization; GO:0051491 (0.01) ! positive regulation of filopodium assembly; GO:0051315 (0.01) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051301 (0.01) ! cell division; GO:0051282 (0.01) ! regulation of sequestering of calcium ion; GO:0051276 (0.01) ! chromosome organization; GO:0051224 (0.01) ! negative regulation of protein transport; GO:0051091 (0.01) ! positive regulation of sequence-specific DNA binding transcription factor activity; GO:0051052 (0.01) ! regulation of DNA metabolic process; GO:0050982 (0.01) ! detection of mechanical stimulus; GO:0050829 (0.01) ! defense response to Gram-negative bacterium; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0048844 (0.01) ! artery morphogenesis; GO:0048739 (0.01) ! cardiac muscle fiber development; GO:0048675 (0.01) ! axon extension; GO:0048489 (0.01) ! synaptic vesicle transport; GO:0048488 (0.01) ! synaptic vesicle endocytosis; GO:0046622 (0.01) ! positive regulation of organ growth; GO:0046578 (0.01) ! regulation of Ras protein signal transduction; GO:0046488 (0.01) ! phosphatidylinositol metabolic process; GO:0046425 (0.01) ! regulation of JAK-STAT cascade; GO:0046331 (0.01) ! lateral inhibition; GO:0046330 (0.01) ! positive regulation of JNK cascade; GO:0045995 (0.01) ! regulation of embryonic development; GO:0045956 (0.01) ! positive regulation of calcium ion-dependent exocytosis; GO:0045931 (0.01) ! positive regulation of mitotic cell cycle; GO:0045773 (0.01) ! positive regulation of axon extension; GO:0045747 (0.01) ! positive regulation of Notch signaling pathway; GO:0045732 (0.01) ! positive regulation of protein catabolic process; GO:0045475 (0.01) ! locomotor rhythm; GO:0045214 (0.01) ! sarcomere organization; GO:0045089 (0.01) ! positive regulation of innate immune response; GO:0044719 (0.01) ! regulation of imaginal disc-derived wing size; GO:0044712 (0.01) ! single-organism catabolic process; GO:0044281 (0.01) ! small molecule metabolic process; GO:0043618 (0.01) ! regulation of transcription from RNA polymerase II promoter in response to stress; GO:0043484 (0.01) ! regulation of RNA splicing; GO:0043406 (0.01) ! positive regulation of MAP kinase activity; GO:0043161 (0.01) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0043044 (0.01) ! ATP-dependent chromatin remodeling; GO:0042752 (0.01) ! regulation of circadian rhythm; GO:0042461 (0.01) ! photoreceptor cell development; GO:0042113 (0.01) ! B cell activation; GO:0042110 (0.01) ! T cell activation; GO:0040005 (0.01) ! chitin-based cuticle attachment to epithelium; GO:0038083 (0.01) ! peptidyl-tyrosine autophosphorylation; GO:0035372 (0.01) ! protein localization to microtubule; GO:0035149 (0.01) ! lumen formation, open tracheal system; GO:0035147 (0.01) ! branch fusion, open tracheal system; GO:0034968 (0.01) ! histone lysine methylation; GO:0034660 (0.01) ! ncRNA metabolic process; GO:0034599 (0.01) ! cellular response to oxidative stress; GO:0034501 (0.01) ! protein localization to kinetochore; GO:0034063 (0.01) ! stress granule assembly; GO:0033962 (0.01) ! cytoplasmic mRNA processing body assembly; GO:0033143 (0.01) ! regulation of intracellular steroid hormone receptor signaling pathway; GO:0032870 (0.01) ! cellular response to hormone stimulus; GO:0032197 (0.01) ! transposition, RNA-mediated; GO:0032147 (0.01) ! activation of protein kinase activity; GO:0031647 (0.01) ! regulation of protein stability; GO:0031338 (0.01) ! regulation of vesicle fusion; GO:0031175 (0.01) ! neuron projection development; GO:0031134 (0.01) ! sister chromatid biorientation; GO:0031124 (0.01) ! mRNA 3'-end processing; GO:0031047 (0.01) ! gene silencing by RNA; GO:0030833 (0.01) ! regulation of actin filament polymerization; GO:0030716 (0.01) ! oocyte fate determination; GO:0030705 (0.01) ! cytoskeleton-dependent intracellular transport; GO:0030534 (0.01) ! adult behavior; GO:0030518 (0.01) ! intracellular steroid hormone receptor signaling pathway; GO:0030431 (0.01) ! sleep; GO:0030336 (0.01) ! negative regulation of cell migration; GO:0030335 (0.01) ! positive regulation of cell migration; GO:0030308 (0.01) ! negative regulation of cell growth; GO:0030258 (0.01) ! lipid modification; GO:0030182 (0.01) ! neuron differentiation; GO:0030098 (0.01) ! lymphocyte differentiation; GO:0030031 (0.01) ! cell projection assembly; GO:0030010 (0.01) ! establishment of cell polarity; GO:0022008 (0.01) ! neurogenesis; GO:0019827 (0.01) ! stem cell population maintenance; GO:0019730 (0.01) ! antimicrobial humoral response; GO:0019233 (0.01) ! sensory perception of pain; GO:0018105 (0.01) ! peptidyl-serine phosphorylation; GO:0017148 (0.01) ! negative regulation of translation; GO:0016575 (0.01) ! histone deacetylation; GO:0016573 (0.01) ! histone acetylation; GO:0016525 (0.01) ! negative regulation of angiogenesis; GO:0016322 (0.01) ! neuron remodeling; GO:0016319 (0.01) ! mushroom body development; GO:0016311 (0.01) ! dephosphorylation; GO:0016266 (0.01) ! O-glycan processing; GO:0016204 (0.01) ! determination of muscle attachment site; GO:0016203 (0.01) ! muscle attachment; GO:0016199 (0.01) ! axon midline choice point recognition; GO:0016197 (0.01) ! endosomal transport; GO:0016032 (0.01) ! viral process; GO:0015672 (0.01) ! monovalent inorganic cation transport; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0014013 (0.01) ! regulation of gliogenesis; GO:0010977 (0.01) ! negative regulation of neuron projection development; GO:0010821 (0.01) ! regulation of mitochondrion organization; GO:0010817 (0.01) ! regulation of hormone levels; GO:0010811 (0.01) ! positive regulation of cell-substrate adhesion; GO:0010761 (0.01) ! fibroblast migration; GO:0010717 (0.01) ! regulation of epithelial to mesenchymal transition; GO:0010632 (0.01) ! regulation of epithelial cell migration; GO:0010603 (0.01) ! regulation of cytoplasmic mRNA processing body assembly; GO:0010506 (0.01) ! regulation of autophagy; GO:0010243 (0.01) ! response to organonitrogen compound; GO:0010045 (0.01) ! response to nickel cation; GO:0009952 (0.01) ! anterior/posterior pattern specification; GO:0009411 (0.01) ! response to UV; GO:0008610 (0.01) ! lipid biosynthetic process; GO:0008582 (0.01) ! regulation of synaptic growth at neuromuscular junction; GO:0008362 (0.01) ! chitin-based embryonic cuticle biosynthetic process; GO:0008360 (0.01) ! regulation of cell shape; GO:0008340 (0.01) ! determination of adult lifespan; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008219 (0.01) ! cell death; GO:0007614 (0.01) ! short-term memory; GO:0007612 (0.01) ! learning; GO:0007605 (0.01) ! sensory perception of sound; GO:0007507 (0.01) ! heart development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007420 (0.01) ! brain development; GO:0007417 (0.01) ! central nervous system development; GO:0007416 (0.01) ! synapse assembly; GO:0007411 (0.01) ! axon guidance; GO:0007379 (0.01) ! segment specification; GO:0007350 (0.01) ! blastoderm segmentation; GO:0007298 (0.01) ! border follicle cell migration; GO:0007283 (0.01) ! spermatogenesis; GO:0007281 (0.01) ! germ cell development; GO:0007274 (0.01) ! neuromuscular synaptic transmission; GO:0007269 (0.01) ! neurotransmitter secretion; GO:0007264 (0.01) ! small GTPase mediated signal transduction; GO:0007219 (0.01) ! Notch signaling pathway; GO:0007094 (0.01) ! mitotic spindle assembly checkpoint; GO:0007044 (0.01) ! cell-substrate junction assembly; GO:0007030 (0.01) ! Golgi organization; GO:0007015 (0.01) ! actin filament organization; GO:0006941 (0.01) ! striated muscle contraction; GO:0006900 (0.01) ! membrane budding; GO:0006892 (0.01) ! post-Golgi vesicle-mediated transport; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006612 (0.01) ! protein targeting to membrane; GO:0006606 (0.01) ! protein import into nucleus; GO:0006469 (0.01) ! negative regulation of protein kinase activity; GO:0006405 (0.01) ! RNA export from nucleus; GO:0006379 (0.01) ! mRNA cleavage; GO:0006367 (0.01) ! transcription initiation from RNA polymerase II promoter; GO:0006366 (0.01) ! transcription from RNA polymerase II promoter; GO:0006342 (0.01) ! chromatin silencing; GO:0006337 (0.01) ! nucleosome disassembly; GO:0006336 (0.01) ! DNA replication-independent nucleosome assembly; GO:0006310 (0.01) ! DNA recombination; GO:0006306 (0.01) ! DNA methylation; GO:0006302 (0.01) ! double-strand break repair; GO:0003007 (0.01) ! heart morphogenesis; GO:0002703 (0.01) ! regulation of leukocyte mediated immunity; GO:0002694 (0.01) ! regulation of leukocyte activation; GO:0002683 (0.01) ! negative regulation of immune system process; GO:0002429 (0.01) ! immune response-activating cell surface receptor signaling pathway; GO:0002252 (0.01) ! immune effector process; GO:0002064 (0.01) ! epithelial cell development; GO:0002027 (0.01) ! regulation of heart rate; GO:0002009 (0.01) ! morphogenesis of an epithelium; GO:0001817 (0.01) ! regulation of cytokine production; GO:0001708 (0.01) ! cell fate specification; GO:0001701 (0.01) ! in utero embryonic development; GO:0001666 (0.01) ! response to hypoxia; GO:0001525 (0.01) ! angiogenesis; GO:0001508 (0.01) ! action potential; GO:0001501 (0.01) ! skeletal system development; GO:0000902 (0.01) ! cell morphogenesis; GO:0000290 (0.01) ! deadenylation-dependent decapping of nuclear-transcribed mRNA; GO:0000278 (0.01) ! mitotic cell cycle; GO:0000209 (0.01) ! protein polyubiquitination GO:0005576 (0.91) ! extracellular region; GO:0044464 (0.90) ! cell part; GO:0044424 (0.77) ! intracellular part; GO:0044421 (0.70) ! extracellular region part; GO:0043226 (0.70) ! organelle; GO:0005615 (0.67) ! extracellular space; GO:0043227 (0.66) ! membrane-bounded organelle; GO:0031982 (0.55) ! vesicle; GO:0031988 (0.54) ! membrane-bounded vesicle; GO:0070062 (0.53) ! extracellular exosome; GO:0016020 (0.53) ! membrane; GO:0044422 (0.48) ! organelle part; GO:0044446 (0.47) ! intracellular organelle part; GO:0044444 (0.42) ! cytoplasmic part; GO:0043229 (0.39) ! intracellular organelle; GO:0005886 (0.36) ! plasma membrane; GO:0043231 (0.32) ! intracellular membrane-bounded organelle; GO:0032991 (0.32) ! macromolecular complex; GO:0005737 (0.30) ! cytoplasm; GO:0043234 (0.29) ! protein complex; GO:0044425 (0.25) ! membrane part; GO:0044459 (0.23) ! plasma membrane part; GO:0005634 (0.23) ! nucleus; GO:0044428 (0.21) ! nuclear part; GO:0043233 (0.20) ! organelle lumen; GO:0072562 (0.19) ! blood microparticle; GO:0044433 (0.17) ! cytoplasmic vesicle part; GO:0019898 (0.17) ! extrinsic component of membrane; GO:0019897 (0.16) ! extrinsic component of plasma membrane; GO:0009986 (0.16) ! cell surface; GO:0031093 (0.15) ! platelet alpha granule lumen; GO:0043232 (0.11) ! intracellular non-membrane-bounded organelle; GO:0044430 (0.10) ! cytoskeletal part; GO:0031232 (0.10) ! extrinsic component of external side of plasma membrane; GO:0031226 (0.10) ! intrinsic component of plasma membrane; GO:0016021 (0.10) ! integral component of membrane; GO:0044451 (0.08) ! nucleoplasm part; GO:0031012 (0.08) ! extracellular matrix; GO:0016023 (0.08) ! cytoplasmic, membrane-bounded vesicle; GO:0005654 (0.08) ! nucleoplasm; GO:0097458 (0.07) ! neuron part; GO:0044432 (0.07) ! endoplasmic reticulum part; GO:0044431 (0.07) ! Golgi apparatus part; GO:0099503 (0.06) ! secretory vesicle; GO:0005829 (0.06) ! cytosol; GO:0005796 (0.06) ! Golgi lumen; GO:1990234 (0.05) ! transferase complex; GO:0046658 (0.05) ! anchored component of plasma membrane; GO:0042995 (0.05) ! cell projection; GO:0030141 (0.05) ! secretory granule; GO:0017053 (0.05) ! transcriptional repressor complex; GO:0005788 (0.05) ! endoplasmic reticulum lumen; GO:0005618 (0.05) ! cell wall; GO:0098796 (0.04) ! membrane protein complex; GO:0070161 (0.04) ! anchoring junction; GO:0044463 (0.04) ! cell projection part; GO:0044427 (0.04) ! chromosomal part; GO:0030529 (0.04) ! intracellular ribonucleoprotein complex; GO:0005887 (0.04) ! integral component of plasma membrane; GO:0061695 (0.03) ! transferase complex, transferring phosphorus-containing groups; GO:0031090 (0.03) ! organelle membrane; GO:0005924 (0.03) ! cell-substrate adherens junction; GO:0005875 (0.03) ! microtubule associated complex; GO:0005874 (0.03) ! microtubule; GO:0005856 (0.03) ! cytoskeleton; GO:0098797 (0.02) ! plasma membrane protein complex; GO:0098590 (0.02) ! plasma membrane region; GO:0098588 (0.02) ! bounding membrane of organelle; GO:0070603 (0.02) ! SWI/SNF superfamily-type complex; GO:0048471 (0.02) ! perinuclear region of cytoplasm; GO:0044798 (0.02) ! nuclear transcription factor complex; GO:0044456 (0.02) ! synapse part; GO:0044454 (0.02) ! nuclear chromosome part; GO:0044449 (0.02) ! contractile fiber part; GO:0043005 (0.02) ! neuron projection; GO:0036464 (0.02) ! cytoplasmic ribonucleoprotein granule; GO:0033267 (0.02) ! axon part; GO:0030426 (0.02) ! growth cone; GO:0030134 (0.02) ! ER to Golgi transport vesicle; GO:0016592 (0.02) ! mediator complex; GO:0005925 (0.02) ! focal adhesion; GO:0005881 (0.02) ! cytoplasmic microtubule; GO:0005819 (0.02) ! spindle; GO:0005815 (0.02) ! microtubule organizing center; GO:0005768 (0.02) ! endosome; GO:0000785 (0.02) ! chromatin; GO:1990316 (0.01) ! ATG1/ULK1 kinase complex; GO:0098552 (0.01) ! side of membrane; GO:0097525 (0.01) ! spliceosomal snRNP complex; GO:0097060 (0.01) ! synaptic membrane; GO:0072686 (0.01) ! mitotic spindle; GO:0071565 (0.01) ! nBAF complex; GO:0071564 (0.01) ! npBAF complex; GO:0071013 (0.01) ! catalytic step 2 spliceosome; GO:0071011 (0.01) ! precatalytic spliceosome; GO:0071004 (0.01) ! U2-type prespliceosome; GO:0070971 (0.01) ! endoplasmic reticulum exit site; GO:0070847 (0.01) ! core mediator complex; GO:0051233 (0.01) ! spindle midzone; GO:0045202 (0.01) ! synapse; GO:0045169 (0.01) ! fusome; GO:0044615 (0.01) ! nuclear pore nuclear basket; GO:0044613 (0.01) ! nuclear pore central transport channel; GO:0044448 (0.01) ! cell cortex part; GO:0044441 (0.01) ! ciliary part; GO:0044295 (0.01) ! axonal growth cone; GO:0043235 (0.01) ! receptor complex; GO:0043195 (0.01) ! terminal bouton; GO:0043025 (0.01) ! neuronal cell body; GO:0035371 (0.01) ! microtubule plus-end; GO:0035097 (0.01) ! histone methyltransferase complex; GO:0031463 (0.01) ! Cul3-RING ubiquitin ligase complex; GO:0031430 (0.01) ! M band; GO:0031234 (0.01) ! extrinsic component of cytoplasmic side of plasma membrane; GO:0031010 (0.01) ! ISWI-type complex; GO:0030877 (0.01) ! beta-catenin destruction complex; GO:0030659 (0.01) ! cytoplasmic vesicle membrane; GO:0030496 (0.01) ! midbody; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030175 (0.01) ! filopodium; GO:0030136 (0.01) ! clathrin-coated vesicle; GO:0030127 (0.01) ! COPII vesicle coat; GO:0030018 (0.01) ! Z disc; GO:0016607 (0.01) ! nuclear speck; GO:0016514 (0.01) ! SWI/SNF complex; GO:0016324 (0.01) ! apical plasma membrane; GO:0015629 (0.01) ! actin cytoskeleton; GO:0014069 (0.01) ! postsynaptic density; GO:0012505 (0.01) ! endomembrane system; GO:0010494 (0.01) ! cytoplasmic stress granule; GO:0005938 (0.01) ! cell cortex; GO:0005929 (0.01) ! cilium; GO:0005927 (0.01) ! muscle tendon junction; GO:0005911 (0.01) ! cell-cell junction; GO:0005905 (0.01) ! clathrin-coated pit; GO:0005891 (0.01) ! voltage-gated calcium channel complex; GO:0005871 (0.01) ! kinesin complex; GO:0005865 (0.01) ! striated muscle thin filament; GO:0005859 (0.01) ! muscle myosin complex; GO:0005847 (0.01) ! mRNA cleavage and polyadenylation specificity factor complex; GO:0005813 (0.01) ! centrosome; GO:0005795 (0.01) ! Golgi stack; GO:0005794 (0.01) ! Golgi apparatus; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005783 (0.01) ! endoplasmic reticulum; GO:0005774 (0.01) ! vacuolar membrane; GO:0005739 (0.01) ! mitochondrion; GO:0005730 (0.01) ! nucleolus; GO:0005694 (0.01) ! chromosome; GO:0005665 (0.01) ! DNA-directed RNA polymerase II, core complex; GO:0005643 (0.01) ! nuclear pore; GO:0005622 (0.01) ! intracellular; GO:0005614 (0.01) ! interstitial matrix; GO:0000943 (0.01) ! retrotransposon nucleocapsid; GO:0000932 (0.01) ! cytoplasmic mRNA processing body; GO:0000922 (0.01) ! spindle pole; GO:0000790 (0.01) ! nuclear chromatin; GO:0000777 (0.01) ! condensed chromosome kinetochore; GO:0000235 (0.01) ! astral microtubule; GO:0000118 (0.01) ! histone deacetylase complex 2 44141906-44162476 (17q21.31) Testis: 29.93; Cells - EBV-transformed lymphocytes: 14.84; Esophagus - Mucosa: 3.92; Skin - Sun Exposed (Lower leg): 3.21; Esophagus - Muscularis: 3.14; Cells - Transformed fibroblasts: 2.75; Adipose - Subcutaneous: 2.71; Skin - Not Sun Exposed (Suprapubic): 2.66; Breast - Mammary Tissue: 2.61; Spleen: 2.40; Nerve - Tibial: 2.33; Vagina: 2.31; Adipose - Visceral (Omentum): 1.98; Ovary: 1.85; Cervix - Endocervix: 1.76; Cervix - Ectocervix: 1.74; Uterus: 1.62; Brain - Cerebellum: 1.57; Fallopian Tube: 1.57; Brain - Cerebellar Hemisphere: 1.54; Prostate: 1.51; Small Intestine - Terminal Ileum: 1.50; Bladder: 1.34; Colon - Transverse: 1.29; Lung: 1.28; Whole Blood: 1.17; Minor Salivary Gland: 1.15; Esophagus - Gastroesophageal Junction: 0.94; Artery - Tibial: 0.93; Pituitary: 0.92; Artery - Coronary: 0.90; Colon - Sigmoid: 0.87; Thyroid: 0.84; Adrenal Gland: 0.78; Stomach: 0.76; Heart - Atrial Appendage: 0.62; Brain - Hypothalamus: 0.60; Artery - Aorta: 0.57; Brain - Spinal cord (cervical c-1): 0.49; Kidney - Cortex: 0.48; Brain - Cortex: 0.46; Muscle - Skeletal: 0.44; Brain - Frontal Cortex (BA9): 0.43; Heart - Left Ventricle: 0.42; Liver: 0.42; Brain - Substantia nigra: 0.32; Brain - Anterior cingulate cortex (BA24): 0.32; Brain - Hippocampus: 0.30; Brain - Amygdala: 0.29; Brain - Nucleus accumbens (basal ganglia): 0.29; Pancreas: 0.25; Brain - Caudate (basal ganglia): 0.24; Brain - Putamen (basal ganglia): 0.20; MACSLQKLFAVEEEFEDEDFLSAVEDAENRFTGSLPVNAGRLRPVSSRPQETVQAQSSRLLLLHPTAPSEALGLPDLDLCLPASSTPSADSRPSCIGAAPLRPVSTSSSWIGNQRRVTVTEVLRETARPQSSALHPLLTFESQQQQVGGFEGPEQDEFDKVLASMELEEPGMELECGVSSEAIPILPAQQREGSVLAKKARVVDLSGSCQKGPVPAIHKAGIMSAQDESLDPVIQCRTPRPPLRPGAVGHLPVPTALTVPTQQLHWEVCPQRSPVQALQPLQAARGTIQSSPQNRFPCQPFQSPSSWLSGKAHLPRPRTPNSSCSTPSRTSSGLFPRIPLQPQAPVSSIGSPVGTPKGPQGALQTPIVTNHLVQLVTAASRTPQQPTHPSTRAKTRRFPGPAGILPHQQSGRSLEDIMVSAPQTPTHGALAKFQTEIVASSQASVEEDFGRGPWLTMKSTLGLDERDPSCFLCTYSIVMVLRKQAALKQLPRNKVPNMAVMIKSLTRSTMDASVVFKDPTGEMQGTVHRLLLETCQNELKPGSVLLLKQIGVFSPSLRNHYLNVTPNNLVHIYSPDSGDGSFLKPSQPFPKDSGSFQHDVAAKPEEGFRTAQNLEAEASPEEELPEADDLDGLLSELPEDFFCGTSS TMUB2 Transmembrane and ubiquitin-like domain-containing protein 2 TMUB2_HUMAN (Q71RG4-1) GO:1990841 (0.41) ! promoter-specific chromatin binding; GO:0051718 (0.41) ! DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates; GO:0045322 (0.41) ! unmethylated CpG binding; GO:0042826 (0.41) ! histone deacetylase binding; GO:0030331 (0.41) ! estrogen receptor binding; GO:0019904 (0.41) ! protein domain specific binding; GO:0008327 (0.41) ! methyl-CpG binding; GO:0008270 (0.41) ! zinc ion binding; GO:0003723 (0.41) ! RNA binding; GO:0003690 (0.41) ! double-stranded DNA binding GO:0009987 (0.92) ! cellular process; GO:0044260 (0.90) ! cellular macromolecule metabolic process; GO:0044238 (0.90) ! primary metabolic process; GO:0019538 (0.78) ! protein metabolic process; GO:0019941 (0.63) ! modification-dependent protein catabolic process; GO:0006511 (0.62) ! ubiquitin-dependent protein catabolic process; GO:0065007 (0.57) ! biological regulation; GO:0043412 (0.56) ! macromolecule modification; GO:0050789 (0.55) ! regulation of biological process; GO:0071840 (0.54) ! cellular component organization or biogenesis; GO:0050794 (0.54) ! regulation of cellular process; GO:0016043 (0.53) ! cellular component organization; GO:0048519 (0.49) ! negative regulation of biological process; GO:0080090 (0.48) ! regulation of primary metabolic process; GO:0060255 (0.48) ! regulation of macromolecule metabolic process; GO:0034641 (0.48) ! cellular nitrogen compound metabolic process; GO:0090304 (0.47) ! nucleic acid metabolic process; GO:0051246 (0.47) ! regulation of protein metabolic process; GO:0050896 (0.47) ! response to stimulus; GO:0048523 (0.47) ! negative regulation of cellular process; GO:0043161 (0.47) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0031323 (0.47) ! regulation of cellular metabolic process; GO:0044699 (0.46) ! single-organism process; GO:0032268 (0.46) ! regulation of cellular protein metabolic process; GO:0006259 (0.46) ! DNA metabolic process; GO:0051716 (0.44) ! cellular response to stimulus; GO:0043933 (0.44) ! macromolecular complex subunit organization; GO:0030433 (0.44) ! ER-associated ubiquitin-dependent protein catabolic process; GO:0006950 (0.44) ! response to stress; GO:0007165 (0.43) ! signal transduction; GO:0032502 (0.42) ! developmental process; GO:0010605 (0.42) ! negative regulation of macromolecule metabolic process; GO:0090116 (0.41) ! C-5 methylation of cytosine; GO:0048522 (0.41) ! positive regulation of cellular process; GO:0044767 (0.41) ! single-organism developmental process; GO:0031324 (0.41) ! negative regulation of cellular metabolic process; GO:0016568 (0.41) ! chromatin modification; GO:0051247 (0.40) ! positive regulation of protein metabolic process; GO:0048856 (0.40) ! anatomical structure development; GO:0044763 (0.40) ! single-organism cellular process; GO:0032269 (0.40) ! negative regulation of cellular protein metabolic process; GO:0035556 (0.38) ! intracellular signal transduction; GO:0032270 (0.38) ! positive regulation of cellular protein metabolic process; GO:0031399 (0.38) ! regulation of protein modification process; GO:0048513 (0.37) ! animal organ development; GO:0042221 (0.37) ! response to chemical; GO:1901538 (0.36) ! changes to DNA methylation involved in embryo development; GO:0033043 (0.36) ! regulation of organelle organization; GO:0031401 (0.36) ! positive regulation of protein modification process; GO:0031400 (0.36) ! negative regulation of protein modification process; GO:0010033 (0.36) ! response to organic substance; GO:0007420 (0.36) ! brain development; GO:1901564 (0.35) ! organonitrogen compound metabolic process; GO:0070887 (0.35) ! cellular response to chemical stimulus; GO:0010468 (0.35) ! regulation of gene expression; GO:0009628 (0.35) ! response to abiotic stimulus; GO:0071310 (0.34) ! cellular response to organic substance; GO:0045935 (0.34) ! positive regulation of nucleobase-containing compound metabolic process; GO:0044710 (0.34) ! single-organism metabolic process; GO:0030154 (0.34) ! cell differentiation; GO:0010639 (0.34) ! negative regulation of organelle organization; GO:0010628 (0.34) ! positive regulation of gene expression; GO:0009719 (0.34) ! response to endogenous stimulus; GO:0000122 (0.34) ! negative regulation of transcription from RNA polymerase II promoter; GO:0045471 (0.33) ! response to ethanol; GO:0043207 (0.33) ! response to external biotic stimulus; GO:0042127 (0.33) ! regulation of cell proliferation; GO:0014070 (0.33) ! response to organic cyclic compound; GO:0009408 (0.33) ! response to heat; GO:0009314 (0.33) ! response to radiation; GO:0001101 (0.33) ! response to acid chemical; GO:1990090 (0.32) ! cellular response to nerve growth factor stimulus; GO:0090309 (0.32) ! positive regulation of methylation-dependent chromatin silencing; GO:0071560 (0.32) ! cellular response to transforming growth factor beta stimulus; GO:0071284 (0.32) ! cellular response to lead ion; GO:0071230 (0.32) ! cellular response to amino acid stimulus; GO:0051573 (0.32) ! negative regulation of histone H3-K9 methylation; GO:0051571 (0.32) ! positive regulation of histone H3-K4 methylation; GO:0046500 (0.32) ! S-adenosylmethionine metabolic process; GO:0046499 (0.32) ! S-adenosylmethioninamine metabolic process; GO:0046498 (0.32) ! S-adenosylhomocysteine metabolic process; GO:0044026 (0.32) ! DNA hypermethylation; GO:0036276 (0.32) ! response to antidepressant; GO:0036120 (0.32) ! cellular response to platelet-derived growth factor stimulus; GO:0033574 (0.32) ! response to testosterone; GO:0033189 (0.32) ! response to vitamin A; GO:0032496 (0.32) ! response to lipopolysaccharide; GO:0032355 (0.32) ! response to estradiol; GO:0031000 (0.32) ! response to caffeine; GO:0030182 (0.32) ! neuron differentiation; GO:0014823 (0.32) ! response to activity; GO:0010424 (0.32) ! DNA methylation on cytosine within a CG sequence; GO:0010216 (0.32) ! maintenance of DNA methylation; GO:0010212 (0.32) ! response to ionizing radiation; GO:0009636 (0.32) ! response to toxic substance; GO:0007568 (0.32) ! aging; GO:0007265 (0.32) ! Ras protein signal transduction; GO:0044267 (0.26) ! cellular protein metabolic process; GO:0006464 (0.25) ! cellular protein modification process; GO:0042176 (0.22) ! regulation of protein catabolic process; GO:0030162 (0.21) ! regulation of proteolysis; GO:1903050 (0.20) ! regulation of proteolysis involved in cellular protein catabolic process; GO:0061136 (0.19) ! regulation of proteasomal protein catabolic process; GO:0042981 (0.18) ! regulation of apoptotic process; GO:0032446 (0.18) ! protein modification by small protein conjugation; GO:0032434 (0.17) ! regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0006996 (0.17) ! organelle organization; GO:0033554 (0.16) ! cellular response to stress; GO:0065008 (0.13) ! regulation of biological quality; GO:0048583 (0.13) ! regulation of response to stimulus; GO:0022607 (0.13) ! cellular component assembly; GO:0016567 (0.13) ! protein ubiquitination; GO:0006974 (0.13) ! cellular response to DNA damage stimulus; GO:0080134 (0.12) ! regulation of response to stress; GO:0051179 (0.12) ! localization; GO:0051276 (0.11) ! chromosome organization; GO:0051234 (0.11) ! establishment of localization; GO:0045732 (0.11) ! positive regulation of protein catabolic process; GO:0044707 (0.11) ! single-multicellular organism process; GO:0080135 (0.10) ! regulation of cellular response to stress; GO:0044702 (0.10) ! single organism reproductive process; GO:0043066 (0.10) ! negative regulation of apoptotic process; GO:0022402 (0.10) ! cell cycle process; GO:1903052 (0.09) ! positive regulation of proteolysis involved in cellular protein catabolic process; GO:0048584 (0.09) ! positive regulation of response to stimulus; GO:0007275 (0.09) ! multicellular organism development; GO:1903046 (0.08) ! meiotic cell cycle process; GO:0072331 (0.08) ! signal transduction by p53 class mediator; GO:0034976 (0.08) ! response to endoplasmic reticulum stress; GO:0009966 (0.08) ! regulation of signal transduction; GO:0006914 (0.08) ! autophagy; GO:1901576 (0.07) ! organic substance biosynthetic process; GO:0090150 (0.07) ! establishment of protein localization to membrane; GO:0050821 (0.07) ! protein stabilization; GO:0044249 (0.07) ! cellular biosynthetic process; GO:0042177 (0.07) ! negative regulation of protein catabolic process; GO:0032436 (0.07) ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0007283 (0.07) ! spermatogenesis; GO:0007166 (0.07) ! cell surface receptor signaling pathway; GO:0006281 (0.07) ! DNA repair; GO:1904294 (0.06) ! positive regulation of ERAD pathway; GO:1902531 (0.06) ! regulation of intracellular signal transduction; GO:0071816 (0.06) ! tail-anchored membrane protein insertion into ER membrane; GO:0070059 (0.06) ! intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; GO:0065009 (0.06) ! regulation of molecular function; GO:0044271 (0.06) ! cellular nitrogen compound biosynthetic process; GO:0042787 (0.06) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0042771 (0.06) ! intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; GO:0034645 (0.06) ! cellular macromolecule biosynthetic process; GO:0032435 (0.06) ! negative regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0031396 (0.06) ! regulation of protein ubiquitination; GO:0030324 (0.06) ! lung development; GO:0018393 (0.06) ! internal peptidyl-lysine acetylation; GO:0009790 (0.06) ! embryo development; GO:0007219 (0.06) ! Notch signaling pathway; GO:0007130 (0.06) ! synaptonemal complex assembly; GO:0006289 (0.06) ! nucleotide-excision repair; GO:0001822 (0.06) ! kidney development; GO:0000209 (0.06) ! protein polyubiquitination; GO:1900407 (0.05) ! regulation of cellular response to oxidative stress; GO:0051051 (0.05) ! negative regulation of transport; GO:0044092 (0.05) ! negative regulation of molecular function; GO:0034622 (0.05) ! cellular macromolecular complex assembly; GO:0031398 (0.05) ! positive regulation of protein ubiquitination; GO:0016236 (0.05) ! macroautophagy; GO:0009967 (0.05) ! positive regulation of signal transduction; GO:0006810 (0.05) ! transport; GO:0001932 (0.05) ! regulation of protein phosphorylation; GO:2001242 (0.04) ! regulation of intrinsic apoptotic signaling pathway; GO:1903071 (0.04) ! positive regulation of ER-associated ubiquitin-dependent protein catabolic process; GO:1902589 (0.04) ! single-organism organelle organization; GO:1901796 (0.04) ! regulation of signal transduction by p53 class mediator; GO:0046907 (0.04) ! intracellular transport; GO:0045116 (0.04) ! protein neddylation; GO:0042592 (0.04) ! homeostatic process; GO:0016032 (0.04) ! viral process; GO:0009968 (0.04) ! negative regulation of signal transduction; GO:0006412 (0.04) ! translation; GO:0002376 (0.04) ! immune system process; GO:0000715 (0.04) ! nucleotide-excision repair, DNA damage recognition; GO:1902175 (0.03) ! regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; GO:1901340 (0.03) ! negative regulation of store-operated calcium channel activity; GO:0090090 (0.03) ! negative regulation of canonical Wnt signaling pathway; GO:0070911 (0.03) ! global genome nucleotide-excision repair; GO:0051438 (0.03) ! regulation of ubiquitin-protein transferase activity; GO:0051348 (0.03) ! negative regulation of transferase activity; GO:0045944 (0.03) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045088 (0.03) ! regulation of innate immune response; GO:0044765 (0.03) ! single-organism transport; GO:0044093 (0.03) ! positive regulation of molecular function; GO:0044088 (0.03) ! regulation of vacuole organization; GO:0043549 (0.03) ! regulation of kinase activity; GO:0043408 (0.03) ! regulation of MAPK cascade; GO:0043123 (0.03) ! positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043065 (0.03) ! positive regulation of apoptotic process; GO:0035973 (0.03) ! aggrephagy; GO:0022603 (0.03) ! regulation of anatomical structure morphogenesis; GO:0019985 (0.03) ! translesion synthesis; GO:0016241 (0.03) ! regulation of macroautophagy; GO:0010821 (0.03) ! regulation of mitochondrion organization; GO:0010803 (0.03) ! regulation of tumor necrosis factor-mediated signaling pathway; GO:0009653 (0.03) ! anatomical structure morphogenesis; GO:0008104 (0.03) ! protein localization; GO:0007179 (0.03) ! transforming growth factor beta receptor signaling pathway; GO:0006952 (0.03) ! defense response; GO:0006294 (0.03) ! nucleotide-excision repair, preincision complex assembly; GO:0001933 (0.03) ! negative regulation of protein phosphorylation; GO:0000717 (0.03) ! nucleotide-excision repair, DNA duplex unwinding; GO:0000422 (0.03) ! mitophagy; GO:1902582 (0.02) ! single-organism intracellular transport; GO:0090263 (0.02) ! positive regulation of canonical Wnt signaling pathway; GO:0075733 (0.02) ! intracellular transport of virus; GO:0071456 (0.02) ! cellular response to hypoxia; GO:0070987 (0.02) ! error-free translesion synthesis; GO:0070423 (0.02) ! nucleotide-binding oligomerization domain containing signaling pathway; GO:0061418 (0.02) ! regulation of transcription from RNA polymerase II promoter in response to hypoxia; GO:0060627 (0.02) ! regulation of vesicle-mediated transport; GO:0060071 (0.02) ! Wnt signaling pathway, planar cell polarity pathway; GO:0051656 (0.02) ! establishment of organelle localization; GO:0051437 (0.02) ! positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition; GO:0051436 (0.02) ! negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; GO:0051092 (0.02) ! positive regulation of NF-kappaB transcription factor activity; GO:0050852 (0.02) ! T cell receptor signaling pathway; GO:0048812 (0.02) ! neuron projection morphogenesis; GO:0045742 (0.02) ! positive regulation of epidermal growth factor receptor signaling pathway; GO:0045087 (0.02) ! innate immune response; GO:0045069 (0.02) ! regulation of viral genome replication; GO:0044087 (0.02) ! regulation of cellular component biogenesis; GO:0043488 (0.02) ! regulation of mRNA stability; GO:0042769 (0.02) ! DNA damage response, detection of DNA damage; GO:0042276 (0.02) ! error-prone translesion synthesis; GO:0042254 (0.02) ! ribosome biogenesis; GO:0042059 (0.02) ! negative regulation of epidermal growth factor receptor signaling pathway; GO:0038128 (0.02) ! ERBB2 signaling pathway; GO:0038095 (0.02) ! Fc-epsilon receptor signaling pathway; GO:0038061 (0.02) ! NIK/NF-kappaB signaling; GO:0036297 (0.02) ! interstrand cross-link repair; GO:0035666 (0.02) ! TRIF-dependent toll-like receptor signaling pathway; GO:0034340 (0.02) ! response to type I interferon; GO:0034220 (0.02) ! ion transmembrane transport; GO:0033209 (0.02) ! tumor necrosis factor-mediated signaling pathway; GO:0032480 (0.02) ! negative regulation of type I interferon production; GO:0031627 (0.02) ! telomeric loop formation; GO:0031145 (0.02) ! anaphase-promoting complex-dependent catabolic process; GO:0030512 (0.02) ! negative regulation of transforming growth factor beta receptor signaling pathway; GO:0022618 (0.02) ! ribonucleoprotein complex assembly; GO:0019068 (0.02) ! virion assembly; GO:0019058 (0.02) ! viral life cycle; GO:0016197 (0.02) ! endosomal transport; GO:0010992 (0.02) ! ubiquitin homeostasis; GO:0010939 (0.02) ! regulation of necrotic cell death; GO:0008543 (0.02) ! fibroblast growth factor receptor signaling pathway; GO:0007623 (0.02) ! circadian rhythm; GO:0007254 (0.02) ! JNK cascade; GO:0007249 (0.02) ! I-kappaB kinase/NF-kappaB signaling; GO:0006977 (0.02) ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; GO:0006364 (0.02) ! rRNA processing; GO:0006297 (0.02) ! nucleotide-excision repair, DNA gap filling; GO:0006296 (0.02) ! nucleotide-excision repair, DNA incision, 5'-to lesion; GO:0006283 (0.02) ! transcription-coupled nucleotide-excision repair; GO:0005978 (0.02) ! glycogen biosynthetic process; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0002755 (0.02) ! MyD88-dependent toll-like receptor signaling pathway; GO:0002223 (0.02) ! stimulatory C-type lectin receptor signaling pathway; GO:0002181 (0.02) ! cytoplasmic translation; GO:0000187 (0.02) ! activation of MAPK activity; GO:0000086 (0.02) ! G2/M transition of mitotic cell cycle; GO:2000785 (0.01) ! regulation of autophagosome assembly; GO:1904379 (0.01) ! protein localization to cytosolic proteasome complex involved in ERAD pathway; GO:1904378 (0.01) ! maintenance of unfolded protein involved in ERAD pathway; GO:1904021 (0.01) ! negative regulation of G-protein coupled receptor internalization; GO:1902527 (0.01) ! positive regulation of protein monoubiquitination; GO:1902255 (0.01) ! positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator; GO:1901797 (0.01) ! negative regulation of signal transduction by p53 class mediator; GO:1901214 (0.01) ! regulation of neuron death; GO:1901097 (0.01) ! negative regulation of autophagosome maturation; GO:1900186 (0.01) ! negative regulation of clathrin-mediated endocytosis; GO:1900034 (0.01) ! regulation of cellular response to heat; GO:0098792 (0.01) ! xenophagy; GO:0098586 (0.01) ! cellular response to virus; GO:0097352 (0.01) ! autophagosome maturation; GO:0097009 (0.01) ! energy homeostasis; GO:0072520 (0.01) ! seminiferous tubule development; GO:0071357 (0.01) ! cellular response to type I interferon; GO:0070389 (0.01) ! chaperone cofactor-dependent protein refolding; GO:0060613 (0.01) ! fat pad development; GO:0051881 (0.01) ! regulation of mitochondrial membrane potential; GO:0051607 (0.01) ! defense response to virus; GO:0051321 (0.01) ! meiotic cell cycle; GO:0050803 (0.01) ! regulation of synapse structure or activity; GO:0048568 (0.01) ! embryonic organ development; GO:0048515 (0.01) ! spermatid differentiation; GO:0047497 (0.01) ! mitochondrion transport along microtubule; GO:0045070 (0.01) ! positive regulation of viral genome replication; GO:0044351 (0.01) ! macropinocytosis; GO:0044182 (0.01) ! filamentous growth of a population of unicellular organisms; GO:0043581 (0.01) ! mycelium development; GO:0042982 (0.01) ! amyloid precursor protein metabolic process; GO:0042048 (0.01) ! olfactory behavior; GO:0036166 (0.01) ! phenotypic switching; GO:0035096 (0.01) ! larval midgut cell programmed cell death; GO:0034605 (0.01) ! cellular response to heat; GO:0034140 (0.01) ! negative regulation of toll-like receptor 3 signaling pathway; GO:0030474 (0.01) ! spindle pole body duplication; GO:0030437 (0.01) ! ascospore formation; GO:0021888 (0.01) ! hypothalamus gonadotrophin-releasing hormone neuron development; GO:0019083 (0.01) ! viral transcription; GO:0016579 (0.01) ! protein deubiquitination; GO:0010224 (0.01) ! response to UV-B; GO:0009751 (0.01) ! response to salicylic acid; GO:0009735 (0.01) ! response to cytokinin; GO:0009733 (0.01) ! response to auxin; GO:0009693 (0.01) ! ethylene biosynthetic process; GO:0009409 (0.01) ! response to cold; GO:0009405 (0.01) ! pathogenesis; GO:0008585 (0.01) ! female gonad development; GO:0008584 (0.01) ! male gonad development; GO:0008283 (0.01) ! cell proliferation; GO:0007613 (0.01) ! memory; GO:0007301 (0.01) ! female germline ring canal formation; GO:0007144 (0.01) ! female meiosis I; GO:0007141 (0.01) ! male meiosis I; GO:0006915 (0.01) ! apoptotic process; GO:0006909 (0.01) ! phagocytosis; GO:0006614 (0.01) ! SRP-dependent cotranslational protein targeting to membrane; GO:0006513 (0.01) ! protein monoubiquitination; GO:0006413 (0.01) ! translational initiation; GO:0002474 (0.01) ! antigen processing and presentation of peptide antigen via MHC class I; GO:0002230 (0.01) ! positive regulation of defense response to virus by host; GO:0002109 (0.01) ! maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S); GO:0000902 (0.01) ! cell morphogenesis; GO:0000184 (0.01) ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0000055 (0.01) ! ribosomal large subunit export from nucleus; GO:0000045 (0.01) ! autophagosome assembly; GO:0000028 (0.01) ! ribosomal small subunit assembly; GO:0000027 (0.01) ! ribosomal large subunit assembly GO:0005634 (1.00) ! nucleus; GO:0044446 (0.91) ! intracellular organelle part; GO:0044428 (0.89) ! nuclear part; GO:0005737 (0.81) ! cytoplasm; GO:0005654 (0.79) ! nucleoplasm; GO:0032991 (0.67) ! macromolecular complex; GO:0043234 (0.64) ! protein complex; GO:0044427 (0.44) ! chromosomal part; GO:0043025 (0.44) ! neuronal cell body; GO:0005721 (0.43) ! pericentric heterochromatin; GO:0005657 (0.43) ! replication fork; GO:0044444 (0.39) ! cytoplasmic part; GO:0005829 (0.27) ! cytosol; GO:0044445 (0.13) ! cytosolic part; GO:0016020 (0.11) ! membrane; GO:0016586 (0.10) ! RSC complex; GO:0044391 (0.07) ! ribosomal subunit; GO:0005886 (0.07) ! plasma membrane; GO:0071818 (0.05) ! BAT3 complex; GO:0044421 (0.05) ! extracellular region part; GO:0031988 (0.05) ! membrane-bounded vesicle; GO:0005783 (0.05) ! endoplasmic reticulum; GO:0005773 (0.05) ! vacuole; GO:0070062 (0.04) ! extracellular exosome; GO:0005794 (0.04) ! Golgi apparatus; GO:0005776 (0.04) ! autophagosome; GO:0005739 (0.04) ! mitochondrion; GO:0005615 (0.04) ! extracellular space; GO:0000151 (0.04) ! ubiquitin ligase complex; GO:0022627 (0.03) ! cytosolic small ribosomal subunit; GO:0022625 (0.03) ! cytosolic large ribosomal subunit; GO:0016235 (0.03) ! aggresome; GO:0005875 (0.03) ! microtubule associated complex; GO:0005774 (0.03) ! vacuolar membrane; GO:0005730 (0.03) ! nucleolus; GO:0071942 (0.02) ! XPC complex; GO:0048471 (0.02) ! perinuclear region of cytoplasm; GO:0043209 (0.02) ! myelin sheath; GO:0030666 (0.02) ! endocytic vesicle membrane; GO:0010008 (0.02) ! endosome membrane; GO:0045335 (0.01) ! phagocytic vesicle; GO:0043005 (0.01) ! neuron projection; GO:0031597 (0.01) ! cytosolic proteasome complex; GO:0031595 (0.01) ! nuclear proteasome complex; GO:0019005 (0.01) ! SCF ubiquitin ligase complex; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005765 (0.01) ! lysosomal membrane; GO:0005704 (0.01) ! polytene chromosome band; GO:0005635 (0.01) ! nuclear envelope; GO:0005622 (0.01) ! intracellular; GO:0005618 (0.01) ! cell wall; GO:0005576 (0.01) ! extracellular region; GO:0000783 (0.01) ! nuclear telomere cap complex GO:0005515 ! protein binding GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 GO:0005515 ! protein binding 44186970-44191731 (17q21.31) High: stomach 2 (glandular cells);stomach 1 (glandular cells);seminal vesicle (glandular cells);colon (endothelial cells; glandular cells; peripheral nerve/ganglion);gallbladder (glandular cells);esophagus (squamous epithelial cells);kidney (cells in tubules);testis (cells in seminiferous ducts; Leydig cells);caudate (neuronal cells);epididymis (glandular cells);adrenal gland (glandular cells);endometrium 1 (glandular cells);heart muscle (myocytes);duodenum (glandular cells);bronchus (respiratory epithelial cells);parathyroid gland (glandular cells);skeletal muscle (myocytes);appendix (glandular cells);liver (hepatocytes);rectum (glandular cells);cervix, uterine (squamous epithelial cells);pancreas (exocrine glandular cells);placenta (trophoblastic cells);fallopian tube (glandular cells);bone marrow (hematopoietic cells);soft tissue 2 (fibroblasts);small intestine (glandular cells);nasopharynx (respiratory epithelial cells);lung (macrophages);skin 1 (fibroblasts; Langerhans; melanocytes);breast (glandular cells);Medium: lung (pneumocytes);kidney (cells in glomeruli);liver (bile duct cells);tonsil (germinal center cells; non-germinal center cells; squamous epithelial cells);thyroid gland (glandular cells);endometrium 1 (cells in endometrial stroma);endometrium 2 (glandular cells);salivary gland (glandular cells);smooth muscle (smooth muscle cells);vagina (squamous epithelial cells);cerebral cortex (glial cells; neuronal cells; neuropil);lymph node (germinal center cells; non-germinal center cells);hippocampus (neuronal cells);urinary bladder (urothelial cells);appendix (lymphoid tissue);breast (myoepithelial cells);prostate (glandular cells);cervix, uterine (glandular cells);pancreas (islets of Langerhans);cerebellum (cells in granular layer; Purkinje cells);spleen (cells in red pulp; cells in white pulp);soft tissue 1 (fibroblasts; peripheral nerve);soft tissue 2 (adipocytes; chondrocytes);ovary (ovarian stroma cells);oral mucosa (squamous epithelial cells);skin 1 (keratinocytes);skin 2 (epidermal cells);Low: cerebellum (cells in molecular layer);hippocampus (glial cells);caudate (glial cells);soft tissue 1 (adipocytes);breast (adipocytes);cerebral cortex (endothelial cells); Testis: 66.97; Spleen: 65.14; Thyroid: 64.86; Cervix - Endocervix: 60.76; Prostate: 53.27; Brain - Cerebellum: 52.39; Brain - Cerebellar Hemisphere: 51.70; Uterus: 49.60; Nerve - Tibial: 47.60; Bladder: 47.01; Fallopian Tube: 46.91; Artery - Tibial: 46.59; Ovary: 46.54; Whole Blood: 46.43; Cervix - Ectocervix: 44.28; Lung: 44.10; Artery - Aorta: 43.17; Artery - Coronary: 43.08; Vagina: 42.80; Breast - Mammary Tissue: 41.12; Colon - Sigmoid: 40.81; Cells - Transformed fibroblasts: 40.20; Adipose - Subcutaneous: 40.17; Esophagus - Gastroesophageal Junction: 39.79; Esophagus - Muscularis: 39.21; Pituitary: 39.13; Small Intestine - Terminal Ileum: 39.02; Minor Salivary Gland: 38.84; Colon - Transverse: 38.81; Skin - Sun Exposed (Lower leg): 36.38; Skin - Not Sun Exposed (Suprapubic): 35.60; Adipose - Visceral (Omentum): 34.73; Esophagus - Mucosa: 33.80; Stomach: 32.60; Adrenal Gland: 32.27; Brain - Cortex: 27.66; Cells - EBV-transformed lymphocytes: 27.56; Brain - Frontal Cortex (BA9): 26.92; Kidney - Cortex: 24.72; Brain - Spinal cord (cervical c-1): 20.10; Brain - Nucleus accumbens (basal ganglia): 18.90; Brain - Hypothalamus: 18.27; Brain - Anterior cingulate cortex (BA24): 17.97; Brain - Caudate (basal ganglia): 16.79; Pancreas: 16.54; Heart - Atrial Appendage: 15.94; Liver: 15.32; Brain - Hippocampus: 15.07; Brain - Substantia nigra: 15.04; Muscle - Skeletal: 14.46; Brain - Amygdala: 14.13; Brain - Putamen (basal ganglia): 13.66; Heart - Left Ventricle: 11.81; MISRHLQNNLMSVDPASSQAMELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVADSGSNQLLGAIVSAGDTSVLHLGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDSTGEAGAGGGVEPSLEHLLDIQGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGALKSKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVPGPSASLAPSATEPPSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYGR FAM171A2 FAM171A2 F1712_HUMAN (A8MVW0-1) GO:1901363 (0.58) ! heterocyclic compound binding; GO:0097159 (0.58) ! organic cyclic compound binding; GO:0003676 (0.56) ! nucleic acid binding; GO:0019899 (0.54) ! enzyme binding; GO:0017016 (0.52) ! Ras GTPase binding; GO:0022892 (0.47) ! substrate-specific transporter activity; GO:0003824 (0.27) ! catalytic activity; GO:0016740 (0.16) ! transferase activity; GO:0022857 (0.10) ! transmembrane transporter activity; GO:0008092 (0.10) ! cytoskeletal protein binding; GO:0022891 (0.09) ! substrate-specific transmembrane transporter activity; GO:0016772 (0.09) ! transferase activity, transferring phosphorus-containing groups; GO:0005198 (0.09) ! structural molecule activity; GO:0016787 (0.08) ! hydrolase activity; GO:0005261 (0.08) ! cation channel activity; GO:0004674 (0.08) ! protein serine/threonine kinase activity; GO:0098772 (0.07) ! molecular function regulator; GO:0003677 (0.07) ! DNA binding; GO:0046873 (0.06) ! metal ion transmembrane transporter activity; GO:0044877 (0.06) ! macromolecular complex binding; GO:0030234 (0.05) ! enzyme regulator activity; GO:0022843 (0.05) ! voltage-gated cation channel activity; GO:0003779 (0.05) ! actin binding; GO:0044212 (0.04) ! transcription regulatory region DNA binding; GO:0016887 (0.04) ! ATPase activity; GO:0015631 (0.04) ! tubulin binding; GO:0005245 (0.04) ! voltage-gated calcium channel activity; GO:0005201 (0.04) ! extracellular matrix structural constituent; GO:0005096 (0.04) ! GTPase activator activity; GO:0004871 (0.04) ! signal transducer activity; GO:0004842 (0.04) ! ubiquitin-protein transferase activity; GO:0003723 (0.04) ! RNA binding; GO:0003712 (0.04) ! transcription cofactor activity; GO:0003682 (0.04) ! chromatin binding; GO:0097367 (0.03) ! carbohydrate derivative binding; GO:0046872 (0.03) ! metal ion binding; GO:0044822 (0.03) ! poly(A) RNA binding; GO:0043565 (0.03) ! sequence-specific DNA binding; GO:0019904 (0.03) ! protein domain specific binding; GO:0008331 (0.03) ! high voltage-gated calcium channel activity; GO:0008289 (0.03) ! lipid binding; GO:0008017 (0.03) ! microtubule binding; GO:0005102 (0.03) ! receptor binding; GO:0004702 (0.03) ! receptor signaling protein serine/threonine kinase activity; GO:0003774 (0.03) ! motor activity; GO:0003700 (0.03) ! transcription factor activity, sequence-specific DNA binding; GO:0002039 (0.03) ! p53 binding; GO:0001076 (0.03) ! transcription factor activity, RNA polymerase II transcription factor binding; GO:0000166 (0.03) ! nucleotide binding; GO:0042802 (0.02) ! identical protein binding; GO:0042623 (0.02) ! ATPase activity, coupled; GO:0032403 (0.02) ! protein complex binding; GO:0030507 (0.02) ! spectrin binding; GO:0019900 (0.02) ! kinase binding; GO:0017137 (0.02) ! Rab GTPase binding; GO:0016788 (0.02) ! hydrolase activity, acting on ester bonds; GO:0015079 (0.02) ! potassium ion transmembrane transporter activity; GO:0008757 (0.02) ! S-adenosylmethionine-dependent methyltransferase activity; GO:0008134 (0.02) ! transcription factor binding; GO:0008093 (0.02) ! cytoskeletal adaptor activity; GO:0008013 (0.02) ! beta-catenin binding; GO:0005543 (0.02) ! phospholipid binding; GO:0005528 (0.02) ! FK506 binding; GO:0005524 (0.02) ! ATP binding; GO:0005200 (0.02) ! structural constituent of cytoskeleton; GO:0005085 (0.02) ! guanyl-nucleotide exchange factor activity; GO:0003777 (0.02) ! microtubule motor activity; GO:0003755 (0.02) ! peptidyl-prolyl cis-trans isomerase activity; GO:0003713 (0.02) ! transcription coactivator activity; GO:0001104 (0.02) ! RNA polymerase II transcription cofactor activity; GO:0000981 (0.02) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0000976 (0.02) ! transcription regulatory region sequence-specific DNA binding; GO:1990841 (0.01) ! promoter-specific chromatin binding; GO:0098641 (0.01) ! cadherin binding involved in cell-cell adhesion; GO:0097493 (0.01) ! structural molecule activity conferring elasticity; GO:0097110 (0.01) ! scaffold protein binding; GO:0071949 (0.01) ! FAD binding; GO:0070975 (0.01) ! FHA domain binding; GO:0061630 (0.01) ! ubiquitin protein ligase activity; GO:0052689 (0.01) ! carboxylic ester hydrolase activity; GO:0051427 (0.01) ! hormone receptor binding; GO:0051371 (0.01) ! muscle alpha-actinin binding; GO:0051015 (0.01) ! actin filament binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0044325 (0.01) ! ion channel binding; GO:0043621 (0.01) ! protein self-association; GO:0043426 (0.01) ! MRF binding; GO:0042803 (0.01) ! protein homodimerization activity; GO:0042800 (0.01) ! histone methyltransferase activity (H3-K4 specific); GO:0042393 (0.01) ! histone binding; GO:0030506 (0.01) ! ankyrin binding; GO:0030332 (0.01) ! cyclin binding; GO:0030165 (0.01) ! PDZ domain binding; GO:0019901 (0.01) ! protein kinase binding; GO:0017049 (0.01) ! GTP-Rho binding; GO:0016709 (0.01) ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; GO:0015171 (0.01) ! amino acid transmembrane transporter activity; GO:0008574 (0.01) ! ATP-dependent microtubule motor activity, plus-end-directed; GO:0008332 (0.01) ! low voltage-gated calcium channel activity; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008270 (0.01) ! zinc ion binding; GO:0008234 (0.01) ! cysteine-type peptidase activity; GO:0008201 (0.01) ! heparin binding; GO:0008190 (0.01) ! eukaryotic initiation factor 4E binding; GO:0008094 (0.01) ! DNA-dependent ATPase activity; GO:0008026 (0.01) ! ATP-dependent helicase activity; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005546 (0.01) ! phosphatidylinositol-4,5-bisphosphate binding; GO:0005544 (0.01) ! calcium-dependent phospholipid binding; GO:0005525 (0.01) ! GTP binding; GO:0005522 (0.01) ! profilin binding; GO:0005518 (0.01) ! collagen binding; GO:0005516 (0.01) ! calmodulin binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005249 (0.01) ! voltage-gated potassium channel activity; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0004930 (0.01) ! G-protein coupled receptor activity; GO:0004857 (0.01) ! enzyme inhibitor activity; GO:0004402 (0.01) ! histone acetyltransferase activity; GO:0004181 (0.01) ! metallocarboxypeptidase activity; GO:0003886 (0.01) ! DNA (cytosine-5-)-methyltransferase activity; GO:0003714 (0.01) ! transcription corepressor activity; GO:0003684 (0.01) ! damaged DNA binding; GO:0001664 (0.01) ! G-protein coupled receptor binding; GO:0001105 (0.01) ! RNA polymerase II transcription coactivator activity; GO:0001085 (0.01) ! RNA polymerase II transcription factor binding; GO:0001078 (0.01) ! transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0001055 (0.01) ! RNA polymerase II activity; GO:0001047 (0.01) ! core promoter binding; GO:0000987 (0.01) ! core promoter proximal region sequence-specific DNA binding; GO:0000977 (0.01) ! RNA polymerase II regulatory region sequence-specific DNA binding; GO:0000287 (0.01) ! magnesium ion binding GO:0009987 (0.74) ! cellular process; GO:0065007 (0.66) ! biological regulation; GO:0050789 (0.60) ! regulation of biological process; GO:0050794 (0.58) ! regulation of cellular process; GO:0016043 (0.52) ! cellular component organization; GO:0051179 (0.49) ! localization; GO:0071704 (0.47) ! organic substance metabolic process; GO:0044238 (0.47) ! primary metabolic process; GO:0044699 (0.46) ! single-organism process; GO:0043170 (0.46) ! macromolecule metabolic process; GO:0006810 (0.46) ! transport; GO:0060255 (0.42) ! regulation of macromolecule metabolic process; GO:0006996 (0.42) ! organelle organization; GO:0080090 (0.41) ! regulation of primary metabolic process; GO:0031323 (0.41) ! regulation of cellular metabolic process; GO:0048519 (0.40) ! negative regulation of biological process; GO:0019538 (0.40) ! protein metabolic process; GO:0051171 (0.39) ! regulation of nitrogen compound metabolic process; GO:0050896 (0.39) ! response to stimulus; GO:0048523 (0.39) ! negative regulation of cellular process; GO:0032879 (0.39) ! regulation of localization; GO:0016192 (0.39) ! vesicle-mediated transport; GO:0010468 (0.39) ! regulation of gene expression; GO:0051641 (0.38) ! cellular localization; GO:0051049 (0.38) ! regulation of transport; GO:0048193 (0.38) ! Golgi vesicle transport; GO:0008104 (0.38) ! protein localization; GO:0006355 (0.38) ! regulation of transcription, DNA-templated; GO:0051128 (0.37) ! regulation of cellular component organization; GO:0044763 (0.37) ! single-organism cellular process; GO:0071702 (0.35) ! organic substance transport; GO:0051246 (0.35) ! regulation of protein metabolic process; GO:0046907 (0.35) ! intracellular transport; GO:0034613 (0.35) ! cellular protein localization; GO:0033043 (0.35) ! regulation of organelle organization; GO:0031324 (0.35) ! negative regulation of cellular metabolic process; GO:0022402 (0.35) ! cell cycle process; GO:0010605 (0.35) ! negative regulation of macromolecule metabolic process; GO:0006357 (0.35) ! regulation of transcription from RNA polymerase II promoter; GO:0045892 (0.34) ! negative regulation of transcription, DNA-templated; GO:0042221 (0.34) ! response to chemical; GO:1901575 (0.33) ! organic substance catabolic process; GO:0051493 (0.33) ! regulation of cytoskeleton organization; GO:0033365 (0.33) ! protein localization to organelle; GO:0032886 (0.33) ! regulation of microtubule-based process; GO:0032880 (0.33) ! regulation of protein localization; GO:0070507 (0.32) ! regulation of microtubule cytoskeleton organization; GO:0060341 (0.32) ! regulation of cellular localization; GO:0051726 (0.32) ! regulation of cell cycle; GO:0051223 (0.32) ! regulation of protein transport; GO:0009057 (0.32) ! macromolecule catabolic process; GO:0051298 (0.31) ! centrosome duplication; GO:0050658 (0.31) ! RNA transport; GO:0046822 (0.31) ! regulation of nucleocytoplasmic transport; GO:0046605 (0.31) ! regulation of centrosome cycle; GO:0033157 (0.31) ! regulation of intracellular protein transport; GO:0030163 (0.31) ! protein catabolic process; GO:0009894 (0.31) ! regulation of catabolic process; GO:0000054 (0.31) ! ribosomal subunit export from nucleus; GO:0044237 (0.23) ! cellular metabolic process; GO:0032502 (0.23) ! developmental process; GO:0044767 (0.22) ! single-organism developmental process; GO:0044260 (0.21) ! cellular macromolecule metabolic process; GO:0065008 (0.20) ! regulation of biological quality; GO:0048856 (0.18) ! anatomical structure development; GO:0048518 (0.18) ! positive regulation of biological process; GO:0032501 (0.18) ! multicellular organismal process; GO:0048522 (0.16) ! positive regulation of cellular process; GO:0044707 (0.15) ! single-multicellular organism process; GO:0009653 (0.14) ! anatomical structure morphogenesis; GO:0007165 (0.14) ! signal transduction; GO:0048869 (0.13) ! cellular developmental process; GO:0044267 (0.13) ! cellular protein metabolic process; GO:0043412 (0.13) ! macromolecule modification; GO:0007010 (0.13) ! cytoskeleton organization; GO:0006464 (0.12) ! cellular protein modification process; GO:0051239 (0.11) ! regulation of multicellular organismal process; GO:0043933 (0.11) ! macromolecular complex subunit organization; GO:0022607 (0.11) ! cellular component assembly; GO:1901360 (0.10) ! organic cyclic compound metabolic process; GO:0035556 (0.10) ! intracellular signal transduction; GO:0006807 (0.10) ! nitrogen compound metabolic process; GO:1902589 (0.09) ! single-organism organelle organization; GO:0090304 (0.09) ! nucleic acid metabolic process; GO:0023051 (0.09) ! regulation of signaling; GO:0010646 (0.09) ! regulation of cell communication; GO:0048731 (0.08) ! system development; GO:0044700 (0.08) ! single organism signaling; GO:0042391 (0.08) ! regulation of membrane potential; GO:0031325 (0.08) ! positive regulation of cellular metabolic process; GO:0010604 (0.08) ! positive regulation of macromolecule metabolic process; GO:1902578 (0.07) ! single-organism localization; GO:0065009 (0.07) ! regulation of molecular function; GO:0051716 (0.07) ! cellular response to stimulus; GO:0050793 (0.07) ! regulation of developmental process; GO:0048646 (0.07) ! anatomical structure formation involved in morphogenesis; GO:0048583 (0.07) ! regulation of response to stimulus; GO:0030030 (0.07) ! cell projection organization; GO:0007267 (0.07) ! cell-cell signaling; GO:0007017 (0.07) ! microtubule-based process; GO:0006950 (0.07) ! response to stress; GO:2000026 (0.06) ! regulation of multicellular organismal development; GO:0071822 (0.06) ! protein complex subunit organization; GO:0065003 (0.06) ! macromolecular complex assembly; GO:0060541 (0.06) ! respiratory system development; GO:0048513 (0.06) ! animal organ development; GO:0045935 (0.06) ! positive regulation of nucleobase-containing compound metabolic process; GO:0044765 (0.06) ! single-organism transport; GO:0032268 (0.06) ! regulation of cellular protein metabolic process; GO:0016070 (0.06) ! RNA metabolic process; GO:0009966 (0.06) ! regulation of signal transduction; GO:0009886 (0.06) ! post-embryonic morphogenesis; GO:0006325 (0.06) ! chromatin organization; GO:0003008 (0.06) ! system process; GO:1903047 (0.05) ! mitotic cell cycle process; GO:1901576 (0.05) ! organic substance biosynthetic process; GO:0086010 (0.05) ! membrane depolarization during action potential; GO:0048858 (0.05) ! cell projection morphogenesis; GO:0045595 (0.05) ! regulation of cell differentiation; GO:0044249 (0.05) ! cellular biosynthetic process; GO:0044057 (0.05) ! regulation of system process; GO:0035239 (0.05) ! tube morphogenesis; GO:0033554 (0.05) ! cellular response to stress; GO:0031399 (0.05) ! regulation of protein modification process; GO:0031328 (0.05) ! positive regulation of cellular biosynthetic process; GO:0030154 (0.05) ! cell differentiation; GO:0030029 (0.05) ! actin filament-based process; GO:0022603 (0.05) ! regulation of anatomical structure morphogenesis; GO:0018193 (0.05) ! peptidyl-amino acid modification; GO:0010628 (0.05) ! positive regulation of gene expression; GO:0010557 (0.05) ! positive regulation of macromolecule biosynthetic process; GO:0007475 (0.05) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.05) ! open tracheal system development; GO:0006928 (0.05) ! movement of cell or subcellular component; GO:0006886 (0.05) ! intracellular protein transport; GO:0006468 (0.05) ! protein phosphorylation; GO:0006461 (0.05) ! protein complex assembly; GO:0000226 (0.05) ! microtubule cytoskeleton organization; GO:1902531 (0.04) ! regulation of intracellular signal transduction; GO:0090066 (0.04) ! regulation of anatomical structure size; GO:0060627 (0.04) ! regulation of vesicle-mediated transport; GO:0055085 (0.04) ! transmembrane transport; GO:0051240 (0.04) ! positive regulation of multicellular organismal process; GO:0051130 (0.04) ! positive regulation of cellular component organization; GO:0051094 (0.04) ! positive regulation of developmental process; GO:0051050 (0.04) ! positive regulation of transport; GO:0051046 (0.04) ! regulation of secretion; GO:0050790 (0.04) ! regulation of catalytic activity; GO:0048812 (0.04) ! neuron projection morphogenesis; GO:0048729 (0.04) ! tissue morphogenesis; GO:0045893 (0.04) ! positive regulation of transcription, DNA-templated; GO:0045664 (0.04) ! regulation of neuron differentiation; GO:0044093 (0.04) ! positive regulation of molecular function; GO:0044087 (0.04) ! regulation of cellular component biogenesis; GO:0042127 (0.04) ! regulation of cell proliferation; GO:0032446 (0.04) ! protein modification by small protein conjugation; GO:0030036 (0.04) ! actin cytoskeleton organization; GO:0022604 (0.04) ! regulation of cell morphogenesis; GO:0022414 (0.04) ! reproductive process; GO:0019220 (0.04) ! regulation of phosphate metabolic process; GO:0009967 (0.04) ! positive regulation of signal transduction; GO:0008016 (0.04) ! regulation of heart contraction; GO:0006811 (0.04) ! ion transport; GO:1902582 (0.03) ! single-organism intracellular transport; GO:0072657 (0.03) ! protein localization to membrane; GO:0070887 (0.03) ! cellular response to chemical stimulus; GO:0051336 (0.03) ! regulation of hydrolase activity; GO:0051270 (0.03) ! regulation of cellular component movement; GO:0050877 (0.03) ! neurological system process; GO:0050770 (0.03) ! regulation of axonogenesis; GO:0048813 (0.03) ! dendrite morphogenesis; GO:0048638 (0.03) ! regulation of developmental growth; GO:0048598 (0.03) ! embryonic morphogenesis; GO:0048589 (0.03) ! developmental growth; GO:0048468 (0.03) ! cell development; GO:0046331 (0.03) ! lateral inhibition; GO:0045944 (0.03) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045666 (0.03) ! positive regulation of neuron differentiation; GO:0044719 (0.03) ! regulation of imaginal disc-derived wing size; GO:0044710 (0.03) ! single-organism metabolic process; GO:0044702 (0.03) ! single organism reproductive process; GO:0044248 (0.03) ! cellular catabolic process; GO:0044089 (0.03) ! positive regulation of cellular component biogenesis; GO:0043085 (0.03) ! positive regulation of catalytic activity; GO:0042981 (0.03) ! regulation of apoptotic process; GO:0042592 (0.03) ! homeostatic process; GO:0040011 (0.03) ! locomotion; GO:0040005 (0.03) ! chitin-based cuticle attachment to epithelium; GO:0034765 (0.03) ! regulation of ion transmembrane transport; GO:0034654 (0.03) ! nucleobase-containing compound biosynthetic process; GO:0034645 (0.03) ! cellular macromolecule biosynthetic process; GO:0034622 (0.03) ! cellular macromolecular complex assembly; GO:0034220 (0.03) ! ion transmembrane transport; GO:0032970 (0.03) ! regulation of actin filament-based process; GO:0032270 (0.03) ! positive regulation of cellular protein metabolic process; GO:0018105 (0.03) ! peptidyl-serine phosphorylation; GO:0017157 (0.03) ! regulation of exocytosis; GO:0016570 (0.03) ! histone modification; GO:0016567 (0.03) ! protein ubiquitination; GO:0016071 (0.03) ! mRNA metabolic process; GO:0010927 (0.03) ! cellular component assembly involved in morphogenesis; GO:0010639 (0.03) ! negative regulation of organelle organization; GO:0010033 (0.03) ! response to organic substance; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0008362 (0.03) ! chitin-based embryonic cuticle biosynthetic process; GO:0008285 (0.03) ! negative regulation of cell proliferation; GO:0007610 (0.03) ! behavior; GO:0007423 (0.03) ! sensory organ development; GO:0007409 (0.03) ! axonogenesis; GO:0007275 (0.03) ! multicellular organism development; GO:0007166 (0.03) ! cell surface receptor signaling pathway; GO:0007043 (0.03) ! cell-cell junction assembly; GO:0007018 (0.03) ! microtubule-based movement; GO:0006974 (0.03) ! cellular response to DNA damage stimulus; GO:0006816 (0.03) ! calcium ion transport; GO:0006259 (0.03) ! DNA metabolic process; GO:0002376 (0.03) ! immune system process; GO:0002009 (0.03) ! morphogenesis of an epithelium; GO:0001932 (0.03) ! regulation of protein phosphorylation; GO:0001709 (0.03) ! cell fate determination; GO:0001578 (0.03) ! microtubule bundle formation; GO:0000122 (0.03) ! negative regulation of transcription from RNA polymerase II promoter; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:0098910 (0.02) ! regulation of atrial cardiac muscle cell action potential; GO:0097193 (0.02) ! intrinsic apoptotic signaling pathway; GO:0080135 (0.02) ! regulation of cellular response to stress; GO:0072661 (0.02) ! protein targeting to plasma membrane; GO:0071310 (0.02) ! cellular response to organic substance; GO:0061077 (0.02) ! chaperone-mediated protein folding; GO:0051491 (0.02) ! positive regulation of filopodium assembly; GO:0051345 (0.02) ! positive regulation of hydrolase activity; GO:0051315 (0.02) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051276 (0.02) ! chromosome organization; GO:0051248 (0.02) ! negative regulation of protein metabolic process; GO:0051241 (0.02) ! negative regulation of multicellular organismal process; GO:0048870 (0.02) ! cell motility; GO:0045956 (0.02) ! positive regulation of calcium ion-dependent exocytosis; GO:0045859 (0.02) ! regulation of protein kinase activity; GO:0045786 (0.02) ! negative regulation of cell cycle; GO:0045773 (0.02) ! positive regulation of axon extension; GO:0044265 (0.02) ! cellular macromolecule catabolic process; GO:0043414 (0.02) ! macromolecule methylation; GO:0043087 (0.02) ! regulation of GTPase activity; GO:0042787 (0.02) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0035372 (0.02) ! protein localization to microtubule; GO:0035295 (0.02) ! tube development; GO:0035149 (0.02) ! lumen formation, open tracheal system; GO:0035147 (0.02) ! branch fusion, open tracheal system; GO:0034501 (0.02) ! protein localization to kinetochore; GO:0034332 (0.02) ! adherens junction organization; GO:0032844 (0.02) ! regulation of homeostatic process; GO:0032412 (0.02) ! regulation of ion transmembrane transporter activity; GO:0031134 (0.02) ! sister chromatid biorientation; GO:0031032 (0.02) ! actomyosin structure organization; GO:0030716 (0.02) ! oocyte fate determination; GO:0030031 (0.02) ! cell projection assembly; GO:0019725 (0.02) ! cellular homeostasis; GO:0018205 (0.02) ! peptidyl-lysine modification; GO:0016319 (0.02) ! mushroom body development; GO:0016204 (0.02) ! determination of muscle attachment site; GO:0016203 (0.02) ! muscle attachment; GO:0016199 (0.02) ! axon midline choice point recognition; GO:0010959 (0.02) ! regulation of metal ion transport; GO:0010942 (0.02) ! positive regulation of cell death; GO:0010817 (0.02) ! regulation of hormone levels; GO:0010035 (0.02) ! response to inorganic substance; GO:0009888 (0.02) ! tissue development; GO:0009887 (0.02) ! organ morphogenesis; GO:0009605 (0.02) ! response to external stimulus; GO:0007626 (0.02) ! locomotory behavior; GO:0007612 (0.02) ! learning; GO:0007163 (0.02) ! establishment or maintenance of cell polarity; GO:0007026 (0.02) ! negative regulation of microtubule depolymerization; GO:0006508 (0.02) ! proteolysis; GO:0006397 (0.02) ! mRNA processing; GO:0006351 (0.02) ! transcription, DNA-templated; GO:0006338 (0.02) ! chromatin remodeling; GO:0006281 (0.02) ! DNA repair; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0001934 (0.02) ! positive regulation of protein phosphorylation; GO:0001763 (0.02) ! morphogenesis of a branching structure; GO:0001701 (0.02) ! in utero embryonic development; GO:2001259 (0.01) ! positive regulation of cation channel activity; GO:2000651 (0.01) ! positive regulation of sodium ion transmembrane transporter activity; GO:2000311 (0.01) ! regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; GO:2000045 (0.01) ! regulation of G1/S transition of mitotic cell cycle; GO:1905269 (0.01) ! positive regulation of chromatin organization; GO:1903706 (0.01) ! regulation of hemopoiesis; GO:1903321 (0.01) ! negative regulation of protein modification by small protein conjugation or removal; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:1901214 (0.01) ! regulation of neuron death; GO:1901021 (0.01) ! positive regulation of calcium ion transmembrane transporter activity; GO:1901016 (0.01) ! regulation of potassium ion transmembrane transporter activity; GO:0098655 (0.01) ! cation transmembrane transport; GO:0090630 (0.01) ! activation of GTPase activity; GO:0090308 (0.01) ! regulation of methylation-dependent chromatin silencing; GO:0086036 (0.01) ! regulation of cardiac muscle cell membrane potential; GO:0072665 (0.01) ! protein localization to vacuole; GO:0072594 (0.01) ! establishment of protein localization to organelle; GO:0072332 (0.01) ! intrinsic apoptotic signaling pathway by p53 class mediator; GO:0072205 (0.01) ! metanephric collecting duct development; GO:0071897 (0.01) ! DNA biosynthetic process; GO:0071896 (0.01) ! protein localization to adherens junction; GO:0071456 (0.01) ! cellular response to hypoxia; GO:0071407 (0.01) ! cellular response to organic cyclic compound; GO:0071396 (0.01) ! cellular response to lipid; GO:0071363 (0.01) ! cellular response to growth factor stimulus; GO:0071248 (0.01) ! cellular response to metal ion; GO:0070534 (0.01) ! protein K63-linked ubiquitination; GO:0061564 (0.01) ! axon development; GO:0060441 (0.01) ! epithelial tube branching involved in lung morphogenesis; GO:0060411 (0.01) ! cardiac septum morphogenesis; GO:0060271 (0.01) ! cilium morphogenesis; GO:0060249 (0.01) ! anatomical structure homeostasis; GO:0060052 (0.01) ! neurofilament cytoskeleton organization; GO:0060048 (0.01) ! cardiac muscle contraction; GO:0060047 (0.01) ! heart contraction; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0060027 (0.01) ! convergent extension involved in gastrulation; GO:0055114 (0.01) ! oxidation-reduction process; GO:0055082 (0.01) ! cellular chemical homeostasis; GO:0055074 (0.01) ! calcium ion homeostasis; GO:0055013 (0.01) ! cardiac muscle cell development; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0051606 (0.01) ! detection of stimulus; GO:0051601 (0.01) ! exocyst localization; GO:0051597 (0.01) ! response to methylmercury; GO:0051592 (0.01) ! response to calcium ion; GO:0051568 (0.01) ! histone H3-K4 methylation; GO:0051495 (0.01) ! positive regulation of cytoskeleton organization; GO:0051457 (0.01) ! maintenance of protein location in nucleus; GO:0051292 (0.01) ! nuclear pore complex assembly; GO:0051260 (0.01) ! protein homooligomerization; GO:0051224 (0.01) ! negative regulation of protein transport; GO:0051222 (0.01) ! positive regulation of protein transport; GO:0051091 (0.01) ! positive regulation of sequence-specific DNA binding transcription factor activity; GO:0051048 (0.01) ! negative regulation of secretion; GO:0050808 (0.01) ! synapse organization; GO:0050796 (0.01) ! regulation of insulin secretion; GO:0050792 (0.01) ! regulation of viral process; GO:0050776 (0.01) ! regulation of immune response; GO:0050684 (0.01) ! regulation of mRNA processing; GO:0048771 (0.01) ! tissue remodeling; GO:0048608 (0.01) ! reproductive structure development; GO:0048588 (0.01) ! developmental cell growth; GO:0048562 (0.01) ! embryonic organ morphogenesis; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046579 (0.01) ! positive regulation of Ras protein signal transduction; GO:0045936 (0.01) ! negative regulation of phosphate metabolic process; GO:0045930 (0.01) ! negative regulation of mitotic cell cycle; GO:0045787 (0.01) ! positive regulation of cell cycle; GO:0045747 (0.01) ! positive regulation of Notch signaling pathway; GO:0045665 (0.01) ! negative regulation of neuron differentiation; GO:0045214 (0.01) ! sarcomere organization; GO:0045197 (0.01) ! establishment or maintenance of epithelial cell apical/basal polarity; GO:0045186 (0.01) ! zonula adherens assembly; GO:0045176 (0.01) ! apical protein localization; GO:0045110 (0.01) ! intermediate filament bundle assembly; GO:0045087 (0.01) ! innate immune response; GO:0045053 (0.01) ! protein retention in Golgi apparatus; GO:0045017 (0.01) ! glycerolipid biosynthetic process; GO:0044419 (0.01) ! interspecies interaction between organisms; GO:0044281 (0.01) ! small molecule metabolic process; GO:0043507 (0.01) ! positive regulation of JUN kinase activity; GO:0043502 (0.01) ! regulation of muscle adaptation; GO:0043161 (0.01) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043086 (0.01) ! negative regulation of catalytic activity; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0042752 (0.01) ! regulation of circadian rhythm; GO:0042692 (0.01) ! muscle cell differentiation; GO:0042593 (0.01) ! glucose homeostasis; GO:0042493 (0.01) ! response to drug; GO:0042472 (0.01) ! inner ear morphogenesis; GO:0042461 (0.01) ! photoreceptor cell development; GO:0042330 (0.01) ! taxis; GO:0042246 (0.01) ! tissue regeneration; GO:0036309 (0.01) ! protein localization to M-band; GO:0035637 (0.01) ! multicellular organismal signaling; GO:0035264 (0.01) ! multicellular organism growth; GO:0035082 (0.01) ! axoneme assembly; GO:0034644 (0.01) ! cellular response to UV; GO:0034088 (0.01) ! maintenance of mitotic sister chromatid cohesion; GO:0032956 (0.01) ! regulation of actin cytoskeleton organization; GO:0032870 (0.01) ! cellular response to hormone stimulus; GO:0032535 (0.01) ! regulation of cellular component size; GO:0032496 (0.01) ! response to lipopolysaccharide; GO:0032298 (0.01) ! positive regulation of DNA-dependent DNA replication initiation; GO:0031960 (0.01) ! response to corticosteroid; GO:0031648 (0.01) ! protein destabilization; GO:0031347 (0.01) ! regulation of defense response; GO:0031338 (0.01) ! regulation of vesicle fusion; GO:0031122 (0.01) ! cytoplasmic microtubule organization; GO:0031098 (0.01) ! stress-activated protein kinase signaling cascade; GO:0030913 (0.01) ! paranodal junction assembly; GO:0030901 (0.01) ! midbrain development; GO:0030859 (0.01) ! polarized epithelial cell differentiation; GO:0030705 (0.01) ! cytoskeleton-dependent intracellular transport; GO:0030534 (0.01) ! adult behavior; GO:0030518 (0.01) ! intracellular steroid hormone receptor signaling pathway; GO:0030334 (0.01) ! regulation of cell migration; GO:0030326 (0.01) ! embryonic limb morphogenesis; GO:0030317 (0.01) ! sperm motility; GO:0030241 (0.01) ! skeletal muscle myosin thick filament assembly; GO:0030239 (0.01) ! myofibril assembly; GO:0030099 (0.01) ! myeloid cell differentiation; GO:0030042 (0.01) ! actin filament depolymerization; GO:0030010 (0.01) ! establishment of cell polarity; GO:0019932 (0.01) ! second-messenger-mediated signaling; GO:0019827 (0.01) ! stem cell population maintenance; GO:0016575 (0.01) ! histone deacetylation; GO:0016573 (0.01) ! histone acetylation; GO:0016525 (0.01) ! negative regulation of angiogenesis; GO:0016482 (0.01) ! cytosolic transport; GO:0016477 (0.01) ! cell migration; GO:0016197 (0.01) ! endosomal transport; GO:0016080 (0.01) ! synaptic vesicle targeting; GO:0016050 (0.01) ! vesicle organization; GO:0010880 (0.01) ! regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:0010810 (0.01) ! regulation of cell-substrate adhesion; GO:0010666 (0.01) ! positive regulation of cardiac muscle cell apoptotic process; GO:0009306 (0.01) ! protein secretion; GO:0009303 (0.01) ! rRNA transcription; GO:0008360 (0.01) ! regulation of cell shape; GO:0008355 (0.01) ! olfactory learning; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0007615 (0.01) ! anesthesia-resistant memory; GO:0007605 (0.01) ! sensory perception of sound; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007517 (0.01) ! muscle organ development; GO:0007507 (0.01) ! heart development; GO:0007420 (0.01) ! brain development; GO:0007417 (0.01) ! central nervous system development; GO:0007399 (0.01) ! nervous system development; GO:0007369 (0.01) ! gastrulation; GO:0007292 (0.01) ! female gamete generation; GO:0007281 (0.01) ! germ cell development; GO:0007268 (0.01) ! chemical synaptic transmission; GO:0007265 (0.01) ! Ras protein signal transduction; GO:0007219 (0.01) ! Notch signaling pathway; GO:0007186 (0.01) ! G-protein coupled receptor signaling pathway; GO:0007159 (0.01) ! leukocyte cell-cell adhesion; GO:0007064 (0.01) ! mitotic sister chromatid cohesion; GO:0007050 (0.01) ! cell cycle arrest; GO:0007009 (0.01) ! plasma membrane organization; GO:0007005 (0.01) ! mitochondrion organization; GO:0006979 (0.01) ! response to oxidative stress; GO:0006897 (0.01) ! endocytosis; GO:0006893 (0.01) ! Golgi to plasma membrane transport; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006887 (0.01) ! exocytosis; GO:0006412 (0.01) ! translation; GO:0006379 (0.01) ! mRNA cleavage; GO:0006366 (0.01) ! transcription from RNA polymerase II promoter; GO:0006342 (0.01) ! chromatin silencing; GO:0006334 (0.01) ! nucleosome assembly; GO:0006333 (0.01) ! chromatin assembly or disassembly; GO:0006306 (0.01) ! DNA methylation; GO:0003333 (0.01) ! amino acid transmembrane transport; GO:0003143 (0.01) ! embryonic heart tube morphogenesis; GO:0003007 (0.01) ! heart morphogenesis; GO:0003002 (0.01) ! regionalization; GO:0002697 (0.01) ! regulation of immune effector process; GO:0002684 (0.01) ! positive regulation of immune system process; GO:0002315 (0.01) ! marginal zone B cell differentiation; GO:0002064 (0.01) ! epithelial cell development; GO:0002027 (0.01) ! regulation of heart rate; GO:0001654 (0.01) ! eye development; GO:0001501 (0.01) ! skeletal system development; GO:0000956 (0.01) ! nuclear-transcribed mRNA catabolic process; GO:0000904 (0.01) ! cell morphogenesis involved in differentiation; GO:0000724 (0.01) ! double-strand break repair via homologous recombination; GO:0000414 (0.01) ! regulation of histone H3-K36 methylation; GO:0000398 (0.01) ! mRNA splicing, via spliceosome; GO:0000077 (0.01) ! DNA damage checkpoint; GO:0000070 (0.01) ! mitotic sister chromatid segregation GO:0043226 (0.90) ! organelle; GO:0044464 (0.89) ! cell part; GO:0043227 (0.88) ! membrane-bounded organelle; GO:0044424 (0.87) ! intracellular part; GO:0044422 (0.75) ! organelle part; GO:0043229 (0.75) ! intracellular organelle; GO:0044446 (0.74) ! intracellular organelle part; GO:0043231 (0.73) ! intracellular membrane-bounded organelle; GO:0005737 (0.66) ! cytoplasm; GO:0032991 (0.65) ! macromolecular complex; GO:0044444 (0.64) ! cytoplasmic part; GO:0043234 (0.64) ! protein complex; GO:0031982 (0.53) ! vesicle; GO:0031988 (0.52) ! membrane-bounded vesicle; GO:0044421 (0.51) ! extracellular region part; GO:0070062 (0.48) ! extracellular exosome; GO:0005634 (0.48) ! nucleus; GO:0044428 (0.40) ! nuclear part; GO:0016020 (0.40) ! membrane; GO:0044425 (0.38) ! membrane part; GO:0005829 (0.35) ! cytosol; GO:0031090 (0.34) ! organelle membrane; GO:0043232 (0.28) ! intracellular non-membrane-bounded organelle; GO:0044427 (0.25) ! chromosomal part; GO:0000776 (0.24) ! kinetochore; GO:0005654 (0.23) ! nucleoplasm; GO:0098805 (0.19) ! whole membrane; GO:0098796 (0.19) ! membrane protein complex; GO:0098589 (0.19) ! membrane region; GO:0098588 (0.19) ! bounding membrane of organelle; GO:0044451 (0.16) ! nucleoplasm part; GO:0005886 (0.16) ! plasma membrane; GO:0048471 (0.14) ! perinuclear region of cytoplasm; GO:0044431 (0.14) ! Golgi apparatus part; GO:0044430 (0.14) ! cytoskeletal part; GO:0030529 (0.14) ! intracellular ribonucleoprotein complex; GO:0005794 (0.14) ! Golgi apparatus; GO:0031965 (0.13) ! nuclear membrane; GO:0030662 (0.13) ! coated vesicle membrane; GO:0030117 (0.13) ! membrane coat; GO:0015030 (0.13) ! Cajal body; GO:0005730 (0.13) ! nucleolus; GO:0005642 (0.13) ! annulate lamellae; GO:0005635 (0.13) ! nuclear envelope; GO:0016023 (0.09) ! cytoplasmic, membrane-bounded vesicle; GO:0005768 (0.09) ! endosome; GO:0098852 (0.08) ! lytic vacuole membrane; GO:0030665 (0.08) ! clathrin-coated vesicle membrane; GO:0030135 (0.08) ! coated vesicle; GO:0030131 (0.08) ! clathrin adaptor complex; GO:0010008 (0.08) ! endosome membrane; GO:0005816 (0.08) ! spindle pole body; GO:0005802 (0.08) ! trans-Golgi network; GO:0005643 (0.08) ! nuclear pore; GO:1902494 (0.07) ! catalytic complex; GO:0044459 (0.07) ! plasma membrane part; GO:1990234 (0.06) ! transferase complex; GO:0098797 (0.05) ! plasma membrane protein complex; GO:0097458 (0.05) ! neuron part; GO:0061695 (0.05) ! transferase complex, transferring phosphorus-containing groups; GO:0042995 (0.05) ! cell projection; GO:0030054 (0.05) ! cell junction; GO:0005576 (0.05) ! extracellular region; GO:0071561 (0.04) ! nucleus-vacuole junction; GO:0055037 (0.04) ! recycling endosome; GO:0042565 (0.04) ! RNA nuclear export complex; GO:0036020 (0.04) ! endolysosome membrane; GO:0034272 (0.04) ! phosphatidylinositol 3-kinase complex, class III, type II; GO:0034271 (0.04) ! phosphatidylinositol 3-kinase complex, class III, type I; GO:0030669 (0.04) ! clathrin-coated endocytic vesicle membrane; GO:0030663 (0.04) ! COPI-coated vesicle membrane; GO:0030137 (0.04) ! COPI-coated vesicle; GO:0030136 (0.04) ! clathrin-coated vesicle; GO:0030126 (0.04) ! COPI vesicle coat; GO:0030122 (0.04) ! AP-2 adaptor complex; GO:0030118 (0.04) ! clathrin coat; GO:0016363 (0.04) ! nuclear matrix; GO:0008180 (0.04) ! COP9 signalosome; GO:0005912 (0.04) ! adherens junction; GO:0005905 (0.04) ! clathrin-coated pit; GO:0005793 (0.04) ! endoplasmic reticulum-Golgi intermediate compartment; GO:0005777 (0.04) ! peroxisome; GO:0000407 (0.04) ! pre-autophagosomal structure; GO:0000329 (0.04) ! fungal-type vacuole membrane; GO:0000139 (0.04) ! Golgi membrane; GO:0043005 (0.03) ! neuron projection; GO:0031012 (0.03) ! extracellular matrix; GO:0016021 (0.03) ! integral component of membrane; GO:0005911 (0.03) ! cell-cell junction; GO:0005856 (0.03) ! cytoskeleton; GO:0005622 (0.03) ! intracellular; GO:0099513 (0.02) ! polymeric cytoskeletal fiber; GO:0044456 (0.02) ! synapse part; GO:0044449 (0.02) ! contractile fiber part; GO:0033267 (0.02) ! axon part; GO:0005924 (0.02) ! cell-substrate adherens junction; GO:0005887 (0.02) ! integral component of plasma membrane; GO:0005875 (0.02) ! microtubule associated complex; GO:0098590 (0.01) ! plasma membrane region; GO:0070603 (0.01) ! SWI/SNF superfamily-type complex; GO:0045202 (0.01) ! synapse; GO:0045177 (0.01) ! apical part of cell; GO:0045169 (0.01) ! fusome; GO:0045121 (0.01) ! membrane raft; GO:0044798 (0.01) ! nuclear transcription factor complex; GO:0044448 (0.01) ! cell cortex part; GO:0044295 (0.01) ! axonal growth cone; GO:0043034 (0.01) ! costamere; GO:0043025 (0.01) ! neuronal cell body; GO:0035371 (0.01) ! microtubule plus-end; GO:0035097 (0.01) ! histone methyltransferase complex; GO:0031672 (0.01) ! A band; GO:0031430 (0.01) ! M band; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030175 (0.01) ! filopodium; GO:0030018 (0.01) ! Z disc; GO:0016234 (0.01) ! inclusion body; GO:0014069 (0.01) ! postsynaptic density; GO:0012505 (0.01) ! endomembrane system; GO:0009986 (0.01) ! cell surface; GO:0005930 (0.01) ! axoneme; GO:0005927 (0.01) ! muscle tendon junction; GO:0005925 (0.01) ! focal adhesion; GO:0005923 (0.01) ! bicellular tight junction; GO:0005913 (0.01) ! cell-cell adherens junction; GO:0005891 (0.01) ! voltage-gated calcium channel complex; GO:0005871 (0.01) ! kinesin complex; GO:0005819 (0.01) ! spindle; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005694 (0.01) ! chromosome; GO:0005615 (0.01) ! extracellular space; GO:0005578 (0.01) ! proteinaceous extracellular matrix; GO:0000790 (0.01) ! nuclear chromatin; GO:0000777 (0.01) ! condensed chromosome kinetochore; GO:0000235 (0.01) ! astral microtubule; GO:0000118 (0.01) ! histone deacetylase complex GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 44353215-44363875 (17q21.31) Brain - Cerebellar Hemisphere: 35.12; Brain - Cerebellum: 35.00; Brain - Frontal Cortex (BA9): 25.35; Brain - Cortex: 24.67; Brain - Anterior cingulate cortex (BA24): 16.97; Pituitary: 16.93; Brain - Nucleus accumbens (basal ganglia): 14.72; Cervix - Endocervix: 11.60; Brain - Hypothalamus: 11.41; Brain - Caudate (basal ganglia): 10.03; Brain - Amygdala: 9.89; Brain - Hippocampus: 8.84; Brain - Putamen (basal ganglia): 7.61; Ovary: 7.54; Uterus: 6.81; Cervix - Ectocervix: 6.51; Vagina: 3.94; Thyroid: 3.59; Brain - Substantia nigra: 3.51; Esophagus - Mucosa: 3.14; Fallopian Tube: 2.85; Brain - Spinal cord (cervical c-1): 2.28; Nerve - Tibial: 1.87; Prostate: 1.74; Cells - Transformed fibroblasts: 1.57; Skin - Not Sun Exposed (Suprapubic): 1.26; Testis: 1.20; Colon - Sigmoid: 1.20; Adipose - Visceral (Omentum): 1.16; Lung: 1.08; Skin - Sun Exposed (Lower leg): 0.99; Kidney - Cortex: 0.88; Breast - Mammary Tissue: 0.81; Esophagus - Gastroesophageal Junction: 0.76; Adipose - Subcutaneous: 0.76; Heart - Atrial Appendage: 0.71; Esophagus - Muscularis: 0.67; Small Intestine - Terminal Ileum: 0.65; Minor Salivary Gland: 0.63; Colon - Transverse: 0.57; Spleen: 0.54; Adrenal Gland: 0.53; Bladder: 0.48; Cells - EBV-transformed lymphocytes: 0.38; Stomach: 0.36; Artery - Coronary: 0.32; Heart - Left Ventricle: 0.27; Pancreas: 0.20; Artery - Aorta: 0.17; Artery - Tibial: 0.13; Liver: 0.13; Whole Blood: 0.10; Muscle - Skeletal: 0.10; MPPASGPSVLARLLPLLGLLLGSASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPLVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSGNGSWLELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSETRALTVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHLICGGPLEPAPSGDPEAPPPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKGAAEGKTPDFLLSQSVDQLARPPSLGQAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEPAPPEGTAPGPARAFPQPDPQRPQMPGHSGPGGEGGGGGGEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGGGARSTDASLDSGVDVHEARPARRRPAREERERAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK CCDC43 Coiled-coil domain-containing protein 43 CCD43_HUMAN (Q96MW1-1) GO:0008565 (0.13) ! protein transporter activity; GO:0008139 (0.13) ! nuclear localization sequence binding; GO:0005509 (0.10) ! calcium ion binding; GO:0005198 (0.10) ! structural molecule activity; GO:0004871 (0.10) ! signal transducer activity; GO:0004435 (0.10) ! phosphatidylinositol phospholipase C activity; GO:0098641 (0.05) ! cadherin binding involved in cell-cell adhesion; GO:0005516 (0.05) ! calmodulin binding GO:0044699 (0.77) ! single-organism process; GO:0009987 (0.53) ! cellular process; GO:0006810 (0.44) ! transport; GO:0046907 (0.41) ! intracellular transport; GO:0044763 (0.39) ! single-organism cellular process; GO:0006886 (0.38) ! intracellular protein transport; GO:0006606 (0.35) ! protein import into nucleus; GO:0050794 (0.32) ! regulation of cellular process; GO:0006607 (0.32) ! NLS-bearing protein import into nucleus; GO:0016043 (0.29) ! cellular component organization; GO:0071704 (0.25) ! organic substance metabolic process; GO:0044238 (0.25) ! primary metabolic process; GO:0006928 (0.25) ! movement of cell or subcellular component; GO:0032502 (0.23) ! developmental process; GO:0080090 (0.20) ! regulation of primary metabolic process; GO:0060255 (0.20) ! regulation of macromolecule metabolic process; GO:0044237 (0.20) ! cellular metabolic process; GO:0031323 (0.20) ! regulation of cellular metabolic process; GO:0006355 (0.19) ! regulation of transcription, DNA-templated; GO:0048856 (0.17) ! anatomical structure development; GO:0048522 (0.17) ! positive regulation of cellular process; GO:0007017 (0.16) ! microtubule-based process; GO:0006325 (0.16) ! chromatin organization; GO:0051704 (0.15) ! multi-organism process; GO:0006996 (0.15) ! organelle organization; GO:0031325 (0.14) ! positive regulation of cellular metabolic process; GO:0022607 (0.14) ! cellular component assembly; GO:0010604 (0.14) ! positive regulation of macromolecule metabolic process; GO:0006357 (0.14) ! regulation of transcription from RNA polymerase II promoter; GO:0044767 (0.13) ! single-organism developmental process; GO:0043170 (0.13) ! macromolecule metabolic process; GO:0007018 (0.13) ! microtubule-based movement; GO:0048731 (0.12) ! system development; GO:0045893 (0.12) ! positive regulation of transcription, DNA-templated; GO:0044260 (0.12) ! cellular macromolecule metabolic process; GO:0007165 (0.12) ! signal transduction; GO:1902589 (0.11) ! single-organism organelle organization; GO:1901575 (0.11) ! organic substance catabolic process; GO:0048870 (0.11) ! cell motility; GO:0045944 (0.11) ! positive regulation of transcription from RNA polymerase II promoter; GO:0044712 (0.11) ! single-organism catabolic process; GO:0030031 (0.11) ! cell projection assembly; GO:0019538 (0.11) ! protein metabolic process; GO:0009653 (0.11) ! anatomical structure morphogenesis; GO:0007267 (0.11) ! cell-cell signaling; GO:0044780 (0.10) ! bacterial-type flagellum assembly; GO:0035556 (0.10) ! intracellular signal transduction; GO:0016042 (0.10) ! lipid catabolic process; GO:0050896 (0.09) ! response to stimulus; GO:0044267 (0.09) ! cellular protein metabolic process; GO:0006139 (0.09) ! nucleobase-containing compound metabolic process; GO:0090304 (0.08) ! nucleic acid metabolic process; GO:0065008 (0.08) ! regulation of biological quality; GO:0002376 (0.08) ! immune system process; GO:0098609 (0.07) ! cell-cell adhesion; GO:0051707 (0.07) ! response to other organism; GO:0043044 (0.07) ! ATP-dependent chromatin remodeling; GO:0016192 (0.07) ! vesicle-mediated transport; GO:0008586 (0.07) ! imaginal disc-derived wing vein morphogenesis; GO:0007399 (0.07) ! nervous system development; GO:0046331 (0.06) ! lateral inhibition; GO:0044281 (0.06) ! small molecule metabolic process; GO:0019730 (0.06) ! antimicrobial humoral response; GO:0019637 (0.06) ! organophosphate metabolic process; GO:0016055 (0.06) ! Wnt signaling pathway; GO:0007298 (0.06) ! border follicle cell migration; GO:0006796 (0.06) ! phosphate-containing compound metabolic process; GO:0006351 (0.06) ! transcription, DNA-templated; GO:0002121 (0.06) ! inter-male aggressive behavior; GO:1901564 (0.05) ! organonitrogen compound metabolic process; GO:0071973 (0.05) ! bacterial-type flagellum-dependent cell motility; GO:0051128 (0.05) ! regulation of cellular component organization; GO:0048869 (0.05) ! cellular developmental process; GO:0043647 (0.05) ! inositol phosphate metabolic process; GO:0016570 (0.05) ! histone modification; GO:0007268 (0.05) ! chemical synaptic transmission; GO:0007223 (0.05) ! Wnt signaling pathway, calcium modulating pathway; GO:0007186 (0.05) ! G-protein coupled receptor signaling pathway; GO:0006892 (0.05) ! post-Golgi vesicle-mediated transport; GO:0003073 (0.05) ! regulation of systemic arterial blood pressure; GO:2000026 (0.04) ! regulation of multicellular organismal development; GO:0090630 (0.04) ! activation of GTPase activity; GO:0051240 (0.04) ! positive regulation of multicellular organismal process; GO:0051094 (0.04) ! positive regulation of developmental process; GO:0048513 (0.04) ! animal organ development; GO:0045597 (0.04) ! positive regulation of cell differentiation; GO:0044707 (0.04) ! single-multicellular organism process; GO:0031338 (0.04) ! regulation of vesicle fusion; GO:0030111 (0.04) ! regulation of Wnt signaling pathway; GO:0016575 (0.04) ! histone deacetylation; GO:0005975 (0.04) ! carbohydrate metabolic process; GO:0071733 (0.03) ! transcriptional activation by promoter-enhancer looping; GO:0070831 (0.03) ! basement membrane assembly; GO:0070050 (0.03) ! neuron cellular homeostasis; GO:0061053 (0.03) ! somite development; GO:0060828 (0.03) ! regulation of canonical Wnt signaling pathway; GO:0048703 (0.03) ! embryonic viscerocranium morphogenesis; GO:0048589 (0.03) ! developmental growth; GO:0048565 (0.03) ! digestive tract development; GO:0035118 (0.03) ! embryonic pectoral fin morphogenesis; GO:0016203 (0.03) ! muscle attachment; GO:0009303 (0.03) ! rRNA transcription; GO:0007507 (0.03) ! heart development; GO:0007417 (0.03) ! central nervous system development; GO:0006611 (0.03) ! protein export from nucleus; GO:0006412 (0.03) ! translation; GO:0006406 (0.03) ! mRNA export from nucleus; GO:0003146 (0.03) ! heart jogging; GO:0000056 (0.03) ! ribosomal small subunit export from nucleus; GO:0000055 (0.03) ! ribosomal large subunit export from nucleus; GO:1903861 (0.02) ! positive regulation of dendrite extension; GO:0071300 (0.02) ! cellular response to retinoic acid; GO:0060041 (0.02) ! retina development in camera-type eye; GO:0051568 (0.02) ! histone H3-K4 methylation; GO:0048384 (0.02) ! retinoic acid receptor signaling pathway; GO:0044262 (0.02) ! cellular carbohydrate metabolic process; GO:0042461 (0.02) ! photoreceptor cell development; GO:0042119 (0.02) ! neutrophil activation; GO:0035082 (0.02) ! axoneme assembly; GO:0030854 (0.02) ! positive regulation of granulocyte differentiation; GO:0030705 (0.02) ! cytoskeleton-dependent intracellular transport; GO:0030218 (0.02) ! erythrocyte differentiation; GO:0016337 (0.02) ! single organismal cell-cell adhesion; GO:0006508 (0.02) ! proteolysis; GO:0006306 (0.02) ! DNA methylation; GO:0002446 (0.02) ! neutrophil mediated immunity; GO:0072671 (0.01) ! mitochondria-associated ubiquitin-dependent protein catabolic process; GO:0071630 (0.01) ! nucleus-associated proteasomal ubiquitin-dependent protein catabolic process; GO:0050832 (0.01) ! defense response to fungus; GO:0048749 (0.01) ! compound eye development; GO:0048106 (0.01) ! establishment of thoracic bristle planar orientation; GO:0044409 (0.01) ! entry into host; GO:0035321 (0.01) ! maintenance of imaginal disc-derived wing hair orientation; GO:0035222 (0.01) ! wing disc pattern formation; GO:0032436 (0.01) ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0030433 (0.01) ! ER-associated ubiquitin-dependent protein catabolic process; GO:0030431 (0.01) ! sleep; GO:0030177 (0.01) ! positive regulation of Wnt signaling pathway; GO:0007422 (0.01) ! peripheral nervous system development; GO:0007411 (0.01) ! axon guidance; GO:0007403 (0.01) ! glial cell fate determination; GO:0007400 (0.01) ! neuroblast fate determination; GO:0007379 (0.01) ! segment specification; GO:0007173 (0.01) ! epidermal growth factor receptor signaling pathway; GO:0006096 (0.01) ! glycolytic process; GO:0000398 (0.01) ! mRNA splicing, via spliceosome GO:0044464 (1.00) ! cell part; GO:0044424 (0.97) ! intracellular part; GO:0044422 (0.88) ! organelle part; GO:0044446 (0.84) ! intracellular organelle part; GO:0044444 (0.71) ! cytoplasmic part; GO:0005829 (0.70) ! cytosol; GO:0044428 (0.66) ! nuclear part; GO:0043226 (0.56) ! organelle; GO:0005737 (0.53) ! cytoplasm; GO:0005654 (0.51) ! nucleoplasm; GO:0016020 (0.50) ! membrane; GO:0043229 (0.49) ! intracellular organelle; GO:0043227 (0.46) ! membrane-bounded organelle; GO:0032991 (0.46) ! macromolecular complex; GO:0043231 (0.44) ! intracellular membrane-bounded organelle; GO:0043234 (0.43) ! protein complex; GO:0044425 (0.38) ! membrane part; GO:0043228 (0.37) ! non-membrane-bounded organelle; GO:0031090 (0.37) ! organelle membrane; GO:0005643 (0.35) ! nuclear pore; GO:0044463 (0.33) ! cell projection part; GO:0043232 (0.32) ! intracellular non-membrane-bounded organelle; GO:0030054 (0.31) ! cell junction; GO:0031982 (0.28) ! vesicle; GO:0031410 (0.26) ! cytoplasmic vesicle; GO:0098589 (0.25) ! membrane region; GO:0042995 (0.25) ! cell projection; GO:0005886 (0.25) ! plasma membrane; GO:0031988 (0.22) ! membrane-bounded vesicle; GO:0032587 (0.21) ! ruffle membrane; GO:0030659 (0.21) ! cytoplasmic vesicle membrane; GO:0005912 (0.21) ! adherens junction; GO:0005768 (0.21) ! endosome; GO:0005634 (0.21) ! nucleus; GO:0044451 (0.19) ! nucleoplasm part; GO:0044430 (0.17) ! cytoskeletal part; GO:0044431 (0.15) ! Golgi apparatus part; GO:0031965 (0.15) ! nuclear membrane; GO:0030529 (0.15) ! intracellular ribonucleoprotein complex; GO:0016023 (0.15) ! cytoplasmic, membrane-bounded vesicle; GO:0015030 (0.15) ! Cajal body; GO:0005913 (0.15) ! cell-cell adherens junction; GO:0005730 (0.15) ! nucleolus; GO:0005642 (0.15) ! annulate lamellae; GO:0000776 (0.15) ! kinetochore; GO:0044421 (0.13) ! extracellular region part; GO:0005875 (0.13) ! microtubule associated complex; GO:0070062 (0.11) ! extracellular exosome; GO:0055038 (0.10) ! recycling endosome membrane; GO:0048471 (0.10) ! perinuclear region of cytoplasm; GO:0045202 (0.10) ! synapse; GO:0043679 (0.10) ! axon terminus; GO:0043209 (0.10) ! myelin sheath; GO:0043005 (0.10) ! neuron projection; GO:0030137 (0.10) ! COPI-coated vesicle; GO:0009424 (0.10) ! bacterial-type flagellum hook; GO:0005925 (0.10) ! focal adhesion; GO:0005901 (0.10) ! caveola; GO:0005871 (0.10) ! kinesin complex; GO:0005856 (0.10) ! cytoskeleton; GO:0005769 (0.10) ! early endosome; GO:0005635 (0.10) ! nuclear envelope; GO:0005576 (0.10) ! extracellular region; GO:1902494 (0.09) ! catalytic complex; GO:0012505 (0.08) ! endomembrane system; GO:0005622 (0.08) ! intracellular; GO:0031010 (0.07) ! ISWI-type complex; GO:0005700 (0.07) ! polytene chromosome; GO:0045177 (0.06) ! apical part of cell; GO:0016363 (0.06) ! nuclear matrix; GO:0072562 (0.05) ! blood microparticle; GO:0042627 (0.05) ! chylomicron; GO:0042383 (0.05) ! sarcolemma; GO:0034366 (0.05) ! spherical high-density lipoprotein particle; GO:0034365 (0.05) ! discoidal high-density lipoprotein particle; GO:0034361 (0.05) ! very-low-density lipoprotein particle; GO:0030139 (0.05) ! endocytic vesicle; GO:0019898 (0.05) ! extrinsic component of membrane; GO:0009986 (0.05) ! cell surface; GO:0009288 (0.05) ! bacterial-type flagellum; GO:0005802 (0.05) ! trans-Golgi network; GO:0005615 (0.05) ! extracellular space; GO:0000118 (0.04) ! histone deacetylase complex; GO:1990234 (0.03) ! transferase complex; GO:0030286 (0.03) ! dynein complex; GO:0020008 (0.03) ! rhoptry; GO:0070688 (0.02) ! MLL5-L complex; GO:0045171 (0.02) ! intercellular bridge; GO:0005930 (0.02) ! axoneme; GO:0005813 (0.02) ! centrosome; GO:0036266 (0.01) ! Cdc48p-Npl4p-Vms1p AAA ATPase complex; GO:0020002 (0.01) ! host cell plasma membrane; GO:0005945 (0.01) ! 6-phosphofructokinase complex GO:0005829 ! cytosol; GO:0005515 ! protein binding 3 GO:0005515 ! protein binding 44673069-44689779 (17q21.31) Medium: stomach 2 (glandular cells);stomach 1 (glandular cells);seminal vesicle (glandular cells);colon (glandular cells);gallbladder (glandular cells);esophagus (squamous epithelial cells);kidney (cells in tubules);testis (cells in seminiferous ducts; Leydig cells);caudate (neuronal cells);tonsil (germinal center cells; non-germinal center cells; squamous epithelial cells);thyroid gland (glandular cells);epididymis (glandular cells);adrenal gland (glandular cells);endometrium 1 (glandular cells);endometrium 2 (glandular cells);salivary gland (glandular cells);duodenum (glandular cells);cerebral cortex (neuronal cells; neuropil);vagina (squamous epithelial cells);lymph node (germinal center cells; non-germinal center cells);placenta (decidual cells; trophoblastic cells);bronchus (respiratory epithelial cells);parathyroid gland (glandular cells);urinary bladder (urothelial cells);appendix (glandular cells; lymphoid tissue);breast (glandular cells; myoepithelial cells);rectum (glandular cells);prostate (glandular cells);cervix, uterine (squamous epithelial cells);pancreas (exocrine glandular cells);cerebellum (Purkinje cells);fallopian tube (glandular cells);bone marrow (hematopoietic cells);soft tissue 2 (fibroblasts; peripheral nerve);small intestine (glandular cells);soft tissue 1 (fibroblasts);oral mucosa (squamous epithelial cells);skin 2 (epidermal cells);Low: cerebellum (cells in molecular layer);hippocampus (neuronal cells);caudate (glial cells);spleen (cells in red pulp);skin 1 (fibroblasts; keratinocytes; Langerhans; melanocytes);skeletal muscle (myocytes);colon (endothelial cells);heart muscle (myocytes);soft tissue 1 (peripheral nerve);lung (macrophages);ovary (follicle cells);cerebral cortex (endothelial cells; glial cells);kidney (cells in glomeruli);pancreas (islets of Langerhans); Muscle - Skeletal: 27.17; Cells - Transformed fibroblasts: 26.08; Cells - EBV-transformed lymphocytes: 26.07; Brain - Cerebellar Hemisphere: 24.00; Brain - Cerebellum: 18.54; Nerve - Tibial: 18.03; Brain - Spinal cord (cervical c-1): 17.89; Brain - Frontal Cortex (BA9): 15.66; Thyroid: 14.89; Uterus: 14.86; Fallopian Tube: 14.42; Cervix - Ectocervix: 14.17; Vagina: 14.12; Esophagus - Mucosa: 14.08; Cervix - Endocervix: 13.91; Lung: 13.67; Prostate: 13.16; Artery - Coronary: 13.11; Breast - Mammary Tissue: 13.10; Testis: 12.93; Adrenal Gland: 12.88; Adipose - Subcutaneous: 12.87; Spleen: 12.79; Adipose - Visceral (Omentum): 12.58; Bladder: 12.54; Skin - Not Sun Exposed (Suprapubic): 12.27; Ovary: 12.27; Colon - Sigmoid: 12.19; Skin - Sun Exposed (Lower leg): 11.97; Brain - Nucleus accumbens (basal ganglia): 11.91; Brain - Anterior cingulate cortex (BA24): 11.82; Minor Salivary Gland: 11.78; Brain - Cortex: 11.76; Artery - Tibial: 11.65; Brain - Hippocampus: 11.29; Brain - Amygdala: 11.23; Esophagus - Muscularis: 11.03; Artery - Aorta: 11.01; Small Intestine - Terminal Ileum: 10.96; Brain - Hypothalamus: 10.85; Brain - Caudate (basal ganglia): 10.84; Esophagus - Gastroesophageal Junction: 10.76; Colon - Transverse: 10.73; Brain - Substantia nigra: 10.01; Heart - Left Ventricle: 9.47; Stomach: 9.44; Brain - Putamen (basal ganglia): 9.42; Heart - Atrial Appendage: 9.29; Kidney - Cortex: 8.87; Pituitary: 7.79; Pancreas: 6.02; Liver: 3.87; Whole Blood: 2.59; MAAPSEVAAIAPGEGDGGGGGFGSWLDGRLEALGVDRAVYGAYILGILQEEEEEEKLDALQGILSAFLEEDSLLNICKEIVERWSETQNVVTKVKKEDEVQAIATLIEKQAQIVVKPRMVSEEEKQRKAALLAQYADVTDEEDEADEKDDSGATTMNIGSDKLLFRNTNVEDVLNARKLERDSLRDESQRKKEQDKLQRERDKLAKQERKEKEKKRTQRGERKR HIGD1B HIG1 domain family member 1B HIG1B_HUMAN (Q9P298-1) GO:0016740 (0.79) ! transferase activity; GO:0061630 (0.71) ! ubiquitin protein ligase activity; GO:1901265 (0.28) ! nucleoside phosphate binding; GO:0036094 (0.28) ! small molecule binding; GO:0034061 (0.28) ! DNA polymerase activity; GO:0004527 (0.28) ! exonuclease activity GO:0009987 (0.57) ! cellular process; GO:0065007 (0.51) ! biological regulation; GO:0043066 (0.32) ! negative regulation of apoptotic process; GO:0043623 (0.31) ! cellular protein complex assembly; GO:0044699 (0.29) ! single-organism process; GO:0044260 (0.26) ! cellular macromolecule metabolic process; GO:0044238 (0.26) ! primary metabolic process; GO:0033617 (0.25) ! mitochondrial respiratory chain complex IV assembly; GO:0034654 (0.24) ! nucleobase-containing compound biosynthetic process; GO:0034645 (0.24) ! cellular macromolecule biosynthetic process; GO:0006259 (0.24) ! DNA metabolic process; GO:0055070 (0.19) ! copper ion homeostasis; GO:0048149 (0.19) ! behavioral response to ethanol; GO:0090201 (0.10) ! negative regulation of release of cytochrome c from mitochondria; GO:0071902 (0.10) ! positive regulation of protein serine/threonine kinase activity; GO:0071456 (0.10) ! cellular response to hypoxia; GO:0042149 (0.10) ! cellular response to glucose starvation; GO:0097250 (0.08) ! mitochondrial respiratory chain supercomplex assembly; GO:0043161 (0.03) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0044351 (0.02) ! macropinocytosis GO:0044464 (0.95) ! cell part; GO:0044424 (0.94) ! intracellular part; GO:0032991 (0.90) ! macromolecular complex; GO:0044446 (0.88) ! intracellular organelle part; GO:0043234 (0.88) ! protein complex; GO:0043229 (0.86) ! intracellular organelle; GO:0044444 (0.85) ! cytoplasmic part; GO:0043231 (0.80) ! intracellular membrane-bounded organelle; GO:0005634 (0.71) ! nucleus; GO:0044429 (0.53) ! mitochondrial part; GO:0005737 (0.46) ! cytoplasm; GO:0044428 (0.45) ! nuclear part; GO:0044427 (0.45) ! chromosomal part; GO:0044425 (0.43) ! membrane part; GO:0005739 (0.42) ! mitochondrion; GO:0016020 (0.38) ! membrane; GO:0043232 (0.37) ! intracellular non-membrane-bounded organelle; GO:0016021 (0.36) ! integral component of membrane; GO:0097249 (0.32) ! mitochondrial respiratory chain supercomplex; GO:0031305 (0.32) ! integral component of mitochondrial inner membrane; GO:0031090 (0.30) ! organelle membrane; GO:0005829 (0.23) ! cytosol; GO:0005654 (0.23) ! nucleoplasm; GO:0000776 (0.23) ! kinetochore; GO:0005743 (0.21) ! mitochondrial inner membrane; GO:0061695 (0.17) ! transferase complex, transferring phosphorus-containing groups; GO:0044454 (0.17) ! nuclear chromosome part; GO:0030529 (0.17) ! intracellular ribonucleoprotein complex; GO:0005730 (0.17) ! nucleolus; GO:0005635 (0.17) ! nuclear envelope; GO:0048471 (0.11) ! perinuclear region of cytoplasm; GO:0042575 (0.11) ! DNA polymerase complex; GO:0031965 (0.11) ! nuclear membrane; GO:0016363 (0.11) ! nuclear matrix; GO:0015030 (0.11) ! Cajal body; GO:0005816 (0.11) ! spindle pole body; GO:0005657 (0.11) ! replication fork; GO:0005642 (0.11) ! annulate lamellae; GO:0043625 (0.05) ! delta DNA polymerase complex; GO:0042565 (0.05) ! RNA nuclear export complex; GO:0022625 (0.05) ! cytosolic large ribosomal subunit; GO:0008622 (0.05) ! epsilon DNA polymerase complex; GO:0005840 (0.05) ! ribosome; GO:0005658 (0.05) ! alpha DNA polymerase:primase complex; GO:0005643 (0.05) ! nuclear pore; GO:0005622 (0.05) ! intracellular; GO:0000785 (0.05) ! chromatin; GO:0005886 (0.04) ! plasma membrane; GO:0005783 (0.02) ! endoplasmic reticulum GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 2 44846353-44850480 (17q21.31) Lung: 40.38; Brain - Substantia nigra: 21.38; Brain - Putamen (basal ganglia): 20.96; Brain - Caudate (basal ganglia): 19.61; Brain - Frontal Cortex (BA9): 17.02; Brain - Anterior cingulate cortex (BA24): 16.71; Brain - Hippocampus: 15.77; Brain - Cortex: 15.70; Brain - Hypothalamus: 15.58; Heart - Left Ventricle: 15.38; Brain - Amygdala: 15.24; Uterus: 14.89; Brain - Nucleus accumbens (basal ganglia): 13.81; Brain - Spinal cord (cervical c-1): 11.42; Prostate: 10.93; Adipose - Visceral (Omentum): 10.42; Brain - Cerebellum: 9.27; Brain - Cerebellar Hemisphere: 8.86; Esophagus - Muscularis: 8.42; Breast - Mammary Tissue: 8.37; Esophagus - Gastroesophageal Junction: 7.51; Cervix - Endocervix: 6.25; Nerve - Tibial: 6.01; Fallopian Tube: 5.65; Muscle - Skeletal: 5.64; Thyroid: 4.90; Vagina: 4.53; Colon - Sigmoid: 4.38; Esophagus - Mucosa: 4.24; Small Intestine - Terminal Ileum: 3.92; Ovary: 3.49; Cervix - Ectocervix: 3.06; Adipose - Subcutaneous: 2.96; Heart - Atrial Appendage: 2.79; Bladder: 2.67; Stomach: 2.65; Artery - Coronary: 2.30; Colon - Transverse: 2.17; Testis: 2.07; Minor Salivary Gland: 1.47; Skin - Not Sun Exposed (Suprapubic): 1.42; Pancreas: 1.34; Kidney - Cortex: 1.19; Skin - Sun Exposed (Lower leg): 1.12; Pituitary: 0.95; Artery - Aorta: 0.71; Artery - Tibial: 0.60; Spleen: 0.32; Adrenal Gland: 0.29; Liver: 0.23; Cells - EBV-transformed lymphocytes: 0.17; Cells - Transformed fibroblasts: 0.12; Whole Blood: 0.07; MSANRRWWVPPDDEDCVSEKLLRKTRESPLVPIGLGGCLVVAAYRIYRLRSRGSTKMSIHLIHTRVAAQACAVGAIMLGAVYTMYSDYVKRMAQDAGEK FAM187A Ig-like V-type domain-containing protein FAM187A F187A_HUMAN (A6NFU0-1) GO:0004872 (0.55) ! receptor activity; GO:0042802 (0.50) ! identical protein binding; GO:0046983 (0.48) ! protein dimerization activity; GO:0004888 (0.46) ! transmembrane signaling receptor activity; GO:0097367 (0.42) ! carbohydrate derivative binding; GO:0098632 (0.30) ! protein binding involved in cell-cell adhesion; GO:0042803 (0.21) ! protein homodimerization activity; GO:0005102 (0.21) ! receptor binding; GO:0050839 (0.14) ! cell adhesion molecule binding; GO:0003824 (0.14) ! catalytic activity; GO:0016740 (0.12) ! transferase activity; GO:0004672 (0.11) ! protein kinase activity; GO:0005198 (0.09) ! structural molecule activity; GO:0003823 (0.09) ! antigen binding; GO:0008046 (0.08) ! axon guidance receptor activity; GO:0004713 (0.08) ! protein tyrosine kinase activity; GO:0008092 (0.06) ! cytoskeletal protein binding; GO:0004714 (0.06) ! transmembrane receptor protein tyrosine kinase activity; GO:0098772 (0.05) ! molecular function regulator; GO:0019838 (0.05) ! growth factor binding; GO:0005539 (0.05) ! glycosaminoglycan binding; GO:1901681 (0.04) ! sulfur compound binding; GO:0032403 (0.04) ! protein complex binding; GO:0008307 (0.04) ! structural constituent of muscle; GO:0003779 (0.04) ! actin binding; GO:0097493 (0.03) ! structural molecule activity conferring elasticity; GO:0051371 (0.03) ! muscle alpha-actinin binding; GO:0051015 (0.03) ! actin filament binding; GO:0045499 (0.03) ! chemorepellent activity; GO:0038191 (0.03) ! neuropilin binding; GO:0030215 (0.03) ! semaphorin receptor binding; GO:0017134 (0.03) ! fibroblast growth factor binding; GO:0008201 (0.03) ! heparin binding; GO:0005007 (0.03) ! fibroblast growth factor-activated receptor activity; GO:0004860 (0.03) ! protein kinase inhibitor activity; GO:0070851 (0.02) ! growth factor receptor binding; GO:0019899 (0.02) ! enzyme binding; GO:0016787 (0.02) ! hydrolase activity; GO:0005540 (0.02) ! hyaluronic acid binding; GO:0005201 (0.02) ! extracellular matrix structural constituent; GO:0005200 (0.02) ! structural constituent of cytoskeleton; GO:0005021 (0.02) ! vascular endothelial growth factor-activated receptor activity; GO:0004674 (0.02) ! protein serine/threonine kinase activity; GO:1990782 (0.01) ! protein tyrosine kinase binding; GO:0050840 (0.01) ! extracellular matrix binding; GO:0048495 (0.01) ! Roundabout binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0046934 (0.01) ! phosphatidylinositol-4,5-bisphosphate 3-kinase activity; GO:0043548 (0.01) ! phosphatidylinositol 3-kinase binding; GO:0043167 (0.01) ! ion binding; GO:0034987 (0.01) ! immunoglobulin receptor binding; GO:0030506 (0.01) ! ankyrin binding; GO:0030246 (0.01) ! carbohydrate binding; GO:0022891 (0.01) ! substrate-specific transmembrane transporter activity; GO:0019966 (0.01) ! interleukin-1 binding; GO:0019904 (0.01) ! protein domain specific binding; GO:0019902 (0.01) ! phosphatase binding; GO:0005178 (0.01) ! integrin binding; GO:0005154 (0.01) ! epidermal growth factor receptor binding; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0005042 (0.01) ! netrin receptor activity; GO:0005001 (0.01) ! transmembrane receptor protein tyrosine phosphatase activity; GO:0004896 (0.01) ! cytokine receptor activity; GO:0004687 (0.01) ! myosin light chain kinase activity; GO:0004683 (0.01) ! calmodulin-dependent protein kinase activity; GO:0001948 (0.01) ! glycoprotein binding GO:0044699 (0.82) ! single-organism process; GO:0009987 (0.80) ! cellular process; GO:0044763 (0.79) ! single-organism cellular process; GO:0065007 (0.65) ! biological regulation; GO:0050789 (0.65) ! regulation of biological process; GO:0006928 (0.64) ! movement of cell or subcellular component; GO:0050794 (0.63) ! regulation of cellular process; GO:0032502 (0.63) ! developmental process; GO:0044767 (0.60) ! single-organism developmental process; GO:0007411 (0.59) ! axon guidance; GO:0048856 (0.55) ! anatomical structure development; GO:0048869 (0.53) ! cellular developmental process; GO:0016043 (0.53) ! cellular component organization; GO:0051239 (0.52) ! regulation of multicellular organismal process; GO:0007155 (0.52) ! cell adhesion; GO:0048518 (0.51) ! positive regulation of biological process; GO:0050793 (0.50) ! regulation of developmental process; GO:0048583 (0.50) ! regulation of response to stimulus; GO:0009653 (0.50) ! anatomical structure morphogenesis; GO:2000026 (0.49) ! regulation of multicellular organismal development; GO:0098609 (0.49) ! cell-cell adhesion; GO:0051179 (0.49) ! localization; GO:0051128 (0.49) ! regulation of cellular component organization; GO:0045595 (0.49) ! regulation of cell differentiation; GO:0048522 (0.48) ! positive regulation of cellular process; GO:0050896 (0.47) ! response to stimulus; GO:0048523 (0.47) ! negative regulation of cellular process; GO:0032501 (0.47) ! multicellular organismal process; GO:0022603 (0.47) ! regulation of anatomical structure morphogenesis; GO:0010975 (0.47) ! regulation of neuron projection development; GO:0022604 (0.46) ! regulation of cell morphogenesis; GO:0050770 (0.45) ! regulation of axonogenesis; GO:0048584 (0.45) ! positive regulation of response to stimulus; GO:0048468 (0.45) ! cell development; GO:0016477 (0.45) ! cell migration; GO:0009966 (0.45) ! regulation of signal transduction; GO:0008037 (0.45) ! cell recognition; GO:0034613 (0.44) ! cellular protein localization; GO:0080090 (0.43) ! regulation of primary metabolic process; GO:0071205 (0.43) ! protein localization to juxtaparanode region of axon; GO:0060255 (0.43) ! regulation of macromolecule metabolic process; GO:0044237 (0.43) ! cellular metabolic process; GO:0043170 (0.43) ! macromolecule metabolic process; GO:0031323 (0.43) ! regulation of cellular metabolic process; GO:0006810 (0.43) ! transport; GO:0003008 (0.43) ! system process; GO:1902589 (0.42) ! single-organism organelle organization; GO:0048666 (0.42) ! neuron development; GO:0044707 (0.42) ! single-multicellular organism process; GO:0044260 (0.42) ! cellular macromolecule metabolic process; GO:0032268 (0.42) ! regulation of cellular protein metabolic process; GO:0030154 (0.42) ! cell differentiation; GO:0016337 (0.42) ! single organismal cell-cell adhesion; GO:0009967 (0.42) ! positive regulation of signal transduction; GO:0009893 (0.42) ! positive regulation of metabolic process; GO:0007010 (0.42) ! cytoskeleton organization; GO:0006897 (0.42) ! endocytosis; GO:0065008 (0.41) ! regulation of biological quality; GO:0051241 (0.41) ! negative regulation of multicellular organismal process; GO:0051093 (0.41) ! negative regulation of developmental process; GO:0042221 (0.41) ! response to chemical; GO:0032270 (0.41) ! positive regulation of cellular protein metabolic process; GO:0030030 (0.41) ! cell projection organization; GO:0050877 (0.40) ! neurological system process; GO:0050768 (0.40) ! negative regulation of neurogenesis; GO:0048589 (0.40) ! developmental growth; GO:0032989 (0.40) ! cellular component morphogenesis; GO:0010033 (0.40) ! response to organic substance; GO:0050773 (0.39) ! regulation of dendrite development; GO:0048812 (0.39) ! neuron projection morphogenesis; GO:0048675 (0.39) ! axon extension; GO:0044802 (0.39) ! single-organism membrane organization; GO:0044710 (0.39) ! single-organism metabolic process; GO:0043207 (0.39) ! response to external biotic stimulus; GO:0010628 (0.39) ! positive regulation of gene expression; GO:0009628 (0.39) ! response to abiotic stimulus; GO:0008038 (0.39) ! neuron recognition; GO:0007017 (0.39) ! microtubule-based process; GO:0001764 (0.39) ! neuron migration; GO:1904936 (0.38) ! interneuron migration; GO:1903319 (0.38) ! positive regulation of protein maturation; GO:1902284 (0.38) ! neuron projection extension involved in neuron projection guidance; GO:0098581 (0.38) ! detection of external biotic stimulus; GO:0090659 (0.38) ! walking behavior; GO:0070613 (0.38) ! regulation of protein processing; GO:0060167 (0.38) ! regulation of adenosine receptor signaling pathway; GO:0050974 (0.38) ! detection of mechanical stimulus involved in sensory perception; GO:0048708 (0.38) ! astrocyte differentiation; GO:0048167 (0.38) ! regulation of synaptic plasticity; GO:0045862 (0.38) ! positive regulation of proteolysis; GO:0045745 (0.38) ! positive regulation of G-protein coupled receptor protein signaling pathway; GO:0045685 (0.38) ! regulation of glial cell differentiation; GO:0045161 (0.38) ! neuronal ion channel clustering; GO:0043112 (0.38) ! receptor metabolic process; GO:0032536 (0.38) ! regulation of cell projection size; GO:0032291 (0.38) ! axon ensheathment in central nervous system; GO:0031589 (0.38) ! cell-substrate adhesion; GO:0021894 (0.38) ! cerebral cortex GABAergic interneuron development; GO:0021830 (0.38) ! interneuron migration from the subpallium to the cortex; GO:0014003 (0.38) ! oligodendrocyte development; GO:0009593 (0.38) ! detection of chemical stimulus; GO:0008344 (0.38) ! adult locomotory behavior; GO:0007611 (0.38) ! learning or memory; GO:0006898 (0.38) ! receptor-mediated endocytosis; GO:0002237 (0.38) ! response to molecule of bacterial origin; GO:0048731 (0.36) ! system development; GO:0048646 (0.36) ! anatomical structure formation involved in morphogenesis; GO:0007600 (0.36) ! sensory perception; GO:0007413 (0.36) ! axonal fasciculation; GO:1902578 (0.35) ! single-organism localization; GO:0048813 (0.35) ! dendrite morphogenesis; GO:0022607 (0.35) ! cellular component assembly; GO:0097090 (0.34) ! presynaptic membrane organization; GO:0050975 (0.34) ! sensory perception of touch; GO:0044765 (0.34) ! single-organism transport; GO:0007422 (0.33) ! peripheral nervous system development; GO:0010927 (0.31) ! cellular component assembly involved in morphogenesis; GO:0072657 (0.30) ! protein localization to membrane; GO:0071702 (0.30) ! organic substance transport; GO:0051649 (0.30) ! establishment of localization in cell; GO:0045184 (0.30) ! establishment of protein localization; GO:0044700 (0.30) ! single organism signaling; GO:0007043 (0.30) ! cell-cell junction assembly; GO:0090002 (0.29) ! establishment of protein localization to plasma membrane; GO:0035637 (0.29) ! multicellular organismal signaling; GO:0032288 (0.29) ! myelin assembly; GO:0006612 (0.29) ! protein targeting to membrane; GO:0007165 (0.18) ! signal transduction; GO:0007166 (0.16) ! cell surface receptor signaling pathway; GO:0048513 (0.15) ! animal organ development; GO:0098742 (0.13) ! cell-cell adhesion via plasma-membrane adhesion molecules; GO:0007156 (0.12) ! homophilic cell adhesion via plasma membrane adhesion molecules; GO:0032879 (0.09) ! regulation of localization; GO:0007157 (0.09) ! heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0002376 (0.09) ! immune system process; GO:0048585 (0.08) ! negative regulation of response to stimulus; GO:0019538 (0.08) ! protein metabolic process; GO:1902531 (0.07) ! regulation of intracellular signal transduction; GO:0051240 (0.07) ! positive regulation of multicellular organismal process; GO:0051094 (0.07) ! positive regulation of developmental process; GO:0040012 (0.07) ! regulation of locomotion; GO:0007419 (0.07) ! ventral cord development; GO:0007409 (0.07) ! axonogenesis; GO:0006955 (0.07) ! immune response; GO:0006796 (0.07) ! phosphate-containing compound metabolic process; GO:0006464 (0.07) ! cellular protein modification process; GO:0002682 (0.07) ! regulation of immune system process; GO:0001932 (0.07) ! regulation of protein phosphorylation; GO:2000145 (0.06) ! regulation of cell motility; GO:0070593 (0.06) ! dendrite self-avoidance; GO:0048846 (0.06) ! axon extension involved in axon guidance; GO:0048814 (0.06) ! regulation of dendrite morphogenesis; GO:0048638 (0.06) ! regulation of developmental growth; GO:0030036 (0.06) ! actin cytoskeleton organization; GO:0022414 (0.06) ! reproductive process; GO:0016319 (0.06) ! mushroom body development; GO:0009888 (0.06) ! tissue development; GO:0007167 (0.06) ! enzyme linked receptor protein signaling pathway; GO:0006909 (0.06) ! phagocytosis; GO:0006468 (0.06) ! protein phosphorylation; GO:0001667 (0.06) ! ameboidal-type cell migration; GO:0051130 (0.05) ! positive regulation of cellular component organization; GO:0050976 (0.05) ! detection of mechanical stimulus involved in sensory perception of touch; GO:0050790 (0.05) ! regulation of catalytic activity; GO:0050776 (0.05) ! regulation of immune response; GO:0048729 (0.05) ! tissue morphogenesis; GO:0045597 (0.05) ! positive regulation of cell differentiation; GO:0042981 (0.05) ! regulation of apoptotic process; GO:0042127 (0.05) ! regulation of cell proliferation; GO:0040017 (0.05) ! positive regulation of locomotion; GO:0032490 (0.05) ! detection of molecule of bacterial origin; GO:0032101 (0.05) ! regulation of response to external stimulus; GO:0030334 (0.05) ! regulation of cell migration; GO:0021551 (0.05) ! central nervous system morphogenesis; GO:0009968 (0.05) ! negative regulation of signal transduction; GO:0009887 (0.05) ! organ morphogenesis; GO:0007169 (0.05) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0006950 (0.05) ! response to stress; GO:0060429 (0.04) ! epithelium development; GO:0051716 (0.04) ! cellular response to stimulus; GO:0051704 (0.04) ! multi-organism process; GO:0051129 (0.04) ! negative regulation of cellular component organization; GO:0050920 (0.04) ! regulation of chemotaxis; GO:0050769 (0.04) ! positive regulation of neurogenesis; GO:0045665 (0.04) ! negative regulation of neuron differentiation; GO:0044702 (0.04) ! single organism reproductive process; GO:0043549 (0.04) ! regulation of kinase activity; GO:0043410 (0.04) ! positive regulation of MAPK cascade; GO:0035556 (0.04) ! intracellular signal transduction; GO:0032102 (0.04) ! negative regulation of response to external stimulus; GO:0031032 (0.04) ! actomyosin structure organization; GO:0030516 (0.04) ! regulation of axon extension; GO:0030335 (0.04) ! positive regulation of cell migration; GO:0008284 (0.04) ! positive regulation of cell proliferation; GO:0007015 (0.04) ! actin filament organization; GO:0003006 (0.04) ! developmental process involved in reproduction; GO:0002684 (0.04) ! positive regulation of immune system process; GO:1902532 (0.03) ! negative regulation of intracellular signal transduction; GO:0071310 (0.03) ! cellular response to organic substance; GO:0060548 (0.03) ! negative regulation of cell death; GO:0060415 (0.03) ! muscle tissue morphogenesis; GO:0055002 (0.03) ! striated muscle cell development; GO:0051049 (0.03) ! regulation of transport; GO:0050778 (0.03) ! positive regulation of immune response; GO:0048843 (0.03) ! negative regulation of axon extension involved in axon guidance; GO:0048598 (0.03) ! embryonic morphogenesis; GO:0045859 (0.03) ! regulation of protein kinase activity; GO:0045214 (0.03) ! sarcomere organization; GO:0045088 (0.03) ! regulation of innate immune response; GO:0044092 (0.03) ! negative regulation of molecular function; GO:0042592 (0.03) ! homeostatic process; GO:0035295 (0.03) ! tube development; GO:0019221 (0.03) ! cytokine-mediated signaling pathway; GO:0010976 (0.03) ! positive regulation of neuron projection development; GO:0010631 (0.03) ! epithelial cell migration; GO:0008543 (0.03) ! fibroblast growth factor receptor signaling pathway; GO:0008283 (0.03) ! cell proliferation; GO:0008045 (0.03) ! motor neuron axon guidance; GO:0007389 (0.03) ! pattern specification process; GO:0006952 (0.03) ! defense response; GO:0006936 (0.03) ! muscle contraction; GO:0006935 (0.03) ! chemotaxis; GO:0002377 (0.03) ! immunoglobulin production; GO:0002009 (0.03) ! morphogenesis of an epithelium; GO:0001933 (0.03) ! negative regulation of protein phosphorylation; GO:0001755 (0.03) ! neural crest cell migration; GO:0001525 (0.03) ! angiogenesis; GO:2000112 (0.02) ! regulation of cellular macromolecule biosynthetic process; GO:1903047 (0.02) ! mitotic cell cycle process; GO:1901701 (0.02) ! cellular response to oxygen-containing compound; GO:0071526 (0.02) ! semaphorin-plexin signaling pathway; GO:0071495 (0.02) ! cellular response to endogenous stimulus; GO:0070372 (0.02) ! regulation of ERK1 and ERK2 cascade; GO:0061061 (0.02) ! muscle structure development; GO:0055008 (0.02) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.02) ! cardiac myofibril assembly; GO:0051707 (0.02) ! response to other organism; GO:0051249 (0.02) ! regulation of lymphocyte activation; GO:0051050 (0.02) ! positive regulation of transport; GO:0050919 (0.02) ! negative chemotaxis; GO:0050808 (0.02) ! synapse organization; GO:0050772 (0.02) ! positive regulation of axonogenesis; GO:0050678 (0.02) ! regulation of epithelial cell proliferation; GO:0048739 (0.02) ! cardiac muscle fiber development; GO:0048639 (0.02) ! positive regulation of developmental growth; GO:0048010 (0.02) ! vascular endothelial growth factor receptor signaling pathway; GO:0046777 (0.02) ! protein autophosphorylation; GO:0046426 (0.02) ! negative regulation of JAK-STAT cascade; GO:0045087 (0.02) ! innate immune response; GO:0044057 (0.02) ! regulation of system process; GO:0043085 (0.02) ! positive regulation of catalytic activity; GO:0043066 (0.02) ! negative regulation of apoptotic process; GO:0042493 (0.02) ! response to drug; GO:0042271 (0.02) ! susceptibility to natural killer cell mediated cytotoxicity; GO:0035239 (0.02) ! tube morphogenesis; GO:0033554 (0.02) ! cellular response to stress; GO:0033043 (0.02) ! regulation of organelle organization; GO:0031290 (0.02) ! retinal ganglion cell axon guidance; GO:0031175 (0.02) ! neuron projection development; GO:0030241 (0.02) ! skeletal muscle myosin thick filament assembly; GO:0030240 (0.02) ! skeletal muscle thin filament assembly; GO:0030198 (0.02) ! extracellular matrix organization; GO:0030182 (0.02) ! neuron differentiation; GO:0030155 (0.02) ! regulation of cell adhesion; GO:0030097 (0.02) ! hemopoiesis; GO:0030031 (0.02) ! cell projection assembly; GO:0022612 (0.02) ! gland morphogenesis; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0019219 (0.02) ! regulation of nucleobase-containing compound metabolic process; GO:0018108 (0.02) ! peptidyl-tyrosine phosphorylation; GO:0016199 (0.02) ! axon midline choice point recognition; GO:0010243 (0.02) ! response to organonitrogen compound; GO:0009886 (0.02) ! post-embryonic morphogenesis; GO:0008360 (0.02) ! regulation of cell shape; GO:0008285 (0.02) ! negative regulation of cell proliferation; GO:0007420 (0.02) ! brain development; GO:0007417 (0.02) ! central nervous system development; GO:0007275 (0.02) ! multicellular organism development; GO:0007267 (0.02) ! cell-cell signaling; GO:0007163 (0.02) ! establishment or maintenance of cell polarity; GO:0006959 (0.02) ! humoral immune response; GO:0006941 (0.02) ! striated muscle contraction; GO:0006469 (0.02) ! negative regulation of protein kinase activity; GO:0003002 (0.02) ! regionalization; GO:0002768 (0.02) ! immune response-regulating cell surface receptor signaling pathway; GO:0001817 (0.02) ! regulation of cytokine production; GO:0001501 (0.02) ! skeletal system development; GO:0000902 (0.02) ! cell morphogenesis; GO:2001262 (0.01) ! positive regulation of semaphorin-plexin signaling pathway; GO:2000027 (0.01) ! regulation of organ morphogenesis; GO:1904018 (0.01) ! positive regulation of vasculature development; GO:1903531 (0.01) ! negative regulation of secretion by cell; GO:1903034 (0.01) ! regulation of response to wounding; GO:1902105 (0.01) ! regulation of leukocyte differentiation; GO:1901564 (0.01) ! organonitrogen compound metabolic process; GO:0090263 (0.01) ! positive regulation of canonical Wnt signaling pathway; GO:0072347 (0.01) ! response to anesthetic; GO:0070374 (0.01) ! positive regulation of ERK1 and ERK2 cascade; GO:0061564 (0.01) ! axon development; GO:0061327 (0.01) ! anterior Malpighian tubule development; GO:0060484 (0.01) ! lung-associated mesenchyme development; GO:0060411 (0.01) ! cardiac septum morphogenesis; GO:0060370 (0.01) ! susceptibility to T cell mediated cytotoxicity; GO:0060349 (0.01) ! bone morphogenesis; GO:0060348 (0.01) ! bone development; GO:0060341 (0.01) ! regulation of cellular localization; GO:0060249 (0.01) ! anatomical structure homeostasis; GO:0060219 (0.01) ! camera-type eye photoreceptor cell differentiation; GO:0060045 (0.01) ! positive regulation of cardiac muscle cell proliferation; GO:0055065 (0.01) ! metal ion homeostasis; GO:0055010 (0.01) ! ventricular cardiac muscle tissue morphogenesis; GO:0051963 (0.01) ! regulation of synapse assembly; GO:0051493 (0.01) ! regulation of cytoskeleton organization; GO:0051147 (0.01) ! regulation of muscle cell differentiation; GO:0051057 (0.01) ! positive regulation of small GTPase mediated signal transduction; GO:0050921 (0.01) ! positive regulation of chemotaxis; GO:0050900 (0.01) ! leukocyte migration; GO:0050871 (0.01) ! positive regulation of B cell activation; GO:0050870 (0.01) ! positive regulation of T cell activation; GO:0050853 (0.01) ! B cell receptor signaling pathway; GO:0050764 (0.01) ! regulation of phagocytosis; GO:0050730 (0.01) ! regulation of peptidyl-tyrosine phosphorylation; GO:0050727 (0.01) ! regulation of inflammatory response; GO:0050714 (0.01) ! positive regulation of protein secretion; GO:0050707 (0.01) ! regulation of cytokine secretion; GO:0050680 (0.01) ! negative regulation of epithelial cell proliferation; GO:0050679 (0.01) ! positive regulation of epithelial cell proliferation; GO:0050673 (0.01) ! epithelial cell proliferation; GO:0048863 (0.01) ! stem cell differentiation; GO:0048803 (0.01) ! imaginal disc-derived male genitalia morphogenesis; GO:0048754 (0.01) ! branching morphogenesis of an epithelial tube; GO:0048678 (0.01) ! response to axon injury; GO:0048661 (0.01) ! positive regulation of smooth muscle cell proliferation; GO:0048644 (0.01) ! muscle organ morphogenesis; GO:0048568 (0.01) ! embryonic organ development; GO:0048565 (0.01) ! digestive tract development; GO:0048562 (0.01) ! embryonic organ morphogenesis; GO:0048514 (0.01) ! blood vessel morphogenesis; GO:0048511 (0.01) ! rhythmic process; GO:0048286 (0.01) ! lung alveolus development; GO:0046331 (0.01) ! lateral inhibition; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045824 (0.01) ! negative regulation of innate immune response; GO:0045773 (0.01) ! positive regulation of axon extension; GO:0045765 (0.01) ! regulation of angiogenesis; GO:0045610 (0.01) ! regulation of hemocyte differentiation; GO:0045199 (0.01) ! maintenance of epithelial cell apical/basal polarity; GO:0045165 (0.01) ! cell fate commitment; GO:0044089 (0.01) ! positive regulation of cellular component biogenesis; GO:0043534 (0.01) ! blood vessel endothelial cell migration; GO:0043524 (0.01) ! negative regulation of neuron apoptotic process; GO:0043406 (0.01) ! positive regulation of MAP kinase activity; GO:0043270 (0.01) ! positive regulation of ion transport; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0042742 (0.01) ! defense response to bacterium; GO:0042472 (0.01) ! inner ear morphogenesis; GO:0042246 (0.01) ! tissue regeneration; GO:0042129 (0.01) ! regulation of T cell proliferation; GO:0042059 (0.01) ! negative regulation of epidermal growth factor receptor signaling pathway; GO:0040036 (0.01) ! regulation of fibroblast growth factor receptor signaling pathway; GO:0040014 (0.01) ! regulation of multicellular organism growth; GO:0038202 (0.01) ! TORC1 signaling; GO:0038127 (0.01) ! ERBB signaling pathway; GO:0036335 (0.01) ! intestinal stem cell homeostasis; GO:0035924 (0.01) ! cellular response to vascular endothelial growth factor stimulus; GO:0035385 (0.01) ! Roundabout signaling pathway; GO:0035265 (0.01) ! organ growth; GO:0035172 (0.01) ! hemocyte proliferation; GO:0035167 (0.01) ! larval lymph gland hemopoiesis; GO:0035148 (0.01) ! tube formation; GO:0035107 (0.01) ! appendage morphogenesis; GO:0035099 (0.01) ! hemocyte migration; GO:0034446 (0.01) ! substrate adhesion-dependent cell spreading; GO:0034332 (0.01) ! adherens junction organization; GO:0034109 (0.01) ! homotypic cell-cell adhesion; GO:0033993 (0.01) ! response to lipid; GO:0033564 (0.01) ! anterior/posterior axon guidance; GO:0032970 (0.01) ! regulation of actin filament-based process; GO:0032940 (0.01) ! secretion by cell; GO:0032869 (0.01) ! cellular response to insulin stimulus; GO:0032808 (0.01) ! lacrimal gland development; GO:0031102 (0.01) ! neuron projection regeneration; GO:0030901 (0.01) ! midbrain development; GO:0030855 (0.01) ! epithelial cell differentiation; GO:0030324 (0.01) ! lung development; GO:0030282 (0.01) ! bone mineralization; GO:0030098 (0.01) ! lymphocyte differentiation; GO:0022411 (0.01) ! cellular component disassembly; GO:0021952 (0.01) ! central nervous system projection neuron axonogenesis; GO:0021700 (0.01) ! developmental maturation; GO:0019730 (0.01) ! antimicrobial humoral response; GO:0019725 (0.01) ! cellular homeostasis; GO:0019233 (0.01) ! sensory perception of pain; GO:0019216 (0.01) ! regulation of lipid metabolic process; GO:0016331 (0.01) ! morphogenesis of embryonic epithelium; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0014068 (0.01) ! positive regulation of phosphatidylinositol 3-kinase signaling; GO:0010959 (0.01) ! regulation of metal ion transport; GO:0010906 (0.01) ! regulation of glucose metabolic process; GO:0010842 (0.01) ! retina layer formation; GO:0010638 (0.01) ! positive regulation of organelle organization; GO:0010594 (0.01) ! regulation of endothelial cell migration; GO:0010564 (0.01) ! regulation of cell cycle process; GO:0010518 (0.01) ! positive regulation of phospholipase activity; GO:0010453 (0.01) ! regulation of cell fate commitment; GO:0010035 (0.01) ! response to inorganic substance; GO:0009791 (0.01) ! post-embryonic development; GO:0009058 (0.01) ! biosynthetic process; GO:0009056 (0.01) ! catabolic process; GO:0008589 (0.01) ! regulation of smoothened signaling pathway; GO:0008406 (0.01) ! gonad development; GO:0008039 (0.01) ! synaptic target recognition; GO:0008016 (0.01) ! regulation of heart contraction; GO:0007606 (0.01) ! sensory perception of chemical stimulus; GO:0007565 (0.01) ! female pregnancy; GO:0007520 (0.01) ! myoblast fusion; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007517 (0.01) ! muscle organ development; GO:0007516 (0.01) ! hemocyte development; GO:0007498 (0.01) ! mesoderm development; GO:0007443 (0.01) ! Malpighian tubule morphogenesis; GO:0007435 (0.01) ! salivary gland morphogenesis; GO:0007432 (0.01) ! salivary gland boundary specification; GO:0007423 (0.01) ! sensory organ development; GO:0007416 (0.01) ! synapse assembly; GO:0007415 (0.01) ! defasciculation of motor neuron axon; GO:0007399 (0.01) ! nervous system development; GO:0007346 (0.01) ! regulation of mitotic cell cycle; GO:0007298 (0.01) ! border follicle cell migration; GO:0007283 (0.01) ! spermatogenesis; GO:0007224 (0.01) ! smoothened signaling pathway; GO:0007162 (0.01) ! negative regulation of cell adhesion; GO:0007159 (0.01) ! leukocyte cell-cell adhesion; GO:0006974 (0.01) ! cellular response to DNA damage stimulus; GO:0006958 (0.01) ! complement activation, classical pathway; GO:0006939 (0.01) ! smooth muscle contraction; GO:0006911 (0.01) ! phagocytosis, engulfment; GO:0006910 (0.01) ! phagocytosis, recognition; GO:0006470 (0.01) ! protein dephosphorylation; GO:0003207 (0.01) ! cardiac chamber formation; GO:0003013 (0.01) ! circulatory system process; GO:0002860 (0.01) ! positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; GO:0002064 (0.01) ! epithelial cell development; GO:0002053 (0.01) ! positive regulation of mesenchymal cell proliferation; GO:0002040 (0.01) ! sprouting angiogenesis; GO:0001837 (0.01) ! epithelial to mesenchymal transition; GO:0001819 (0.01) ! positive regulation of cytokine production; GO:0001818 (0.01) ! negative regulation of cytokine production; GO:0001756 (0.01) ! somitogenesis; GO:0001751 (0.01) ! compound eye photoreceptor cell differentiation; GO:0001745 (0.01) ! compound eye morphogenesis; GO:0001701 (0.01) ! in utero embryonic development; GO:0001666 (0.01) ! response to hypoxia; GO:0001657 (0.01) ! ureteric bud development; GO:0001570 (0.01) ! vasculogenesis; GO:0001568 (0.01) ! blood vessel development; GO:0000226 (0.01) ! microtubule cytoskeleton organization; GO:0000165 (0.01) ! MAPK cascade; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter; GO:0000022 (0.01) ! mitotic spindle elongation GO:0044464 (0.98) ! cell part; GO:0031224 (0.93) ! intrinsic component of membrane; GO:0016020 (0.92) ! membrane; GO:0016021 (0.82) ! integral component of membrane; GO:0005886 (0.71) ! plasma membrane; GO:0044459 (0.66) ! plasma membrane part; GO:0097458 (0.59) ! neuron part; GO:0044421 (0.55) ! extracellular region part; GO:0043005 (0.53) ! neuron projection; GO:0030424 (0.52) ! axon; GO:0031226 (0.51) ! intrinsic component of plasma membrane; GO:0005887 (0.50) ! integral component of plasma membrane; GO:0044424 (0.48) ! intracellular part; GO:0030054 (0.43) ! cell junction; GO:0043025 (0.40) ! neuronal cell body; GO:0044444 (0.37) ! cytoplasmic part; GO:0005737 (0.32) ! cytoplasm; GO:0005576 (0.32) ! extracellular region; GO:0030425 (0.31) ! dendrite; GO:0043226 (0.29) ! organelle; GO:0044463 (0.28) ! cell projection part; GO:0043227 (0.27) ! membrane-bounded organelle; GO:0009986 (0.25) ! cell surface; GO:0005615 (0.25) ! extracellular space; GO:0005911 (0.23) ! cell-cell junction; GO:0043234 (0.22) ! protein complex; GO:0031988 (0.22) ! membrane-bounded vesicle; GO:0070062 (0.21) ! extracellular exosome; GO:0005912 (0.21) ! adherens junction; GO:0005604 (0.21) ! basement membrane; GO:0005938 (0.19) ! cell cortex; GO:0098590 (0.18) ! plasma membrane region; GO:0098797 (0.17) ! plasma membrane protein complex; GO:0044422 (0.17) ! organelle part; GO:0043209 (0.16) ! myelin sheath; GO:0031225 (0.15) ! anchored component of membrane; GO:0045202 (0.12) ! synapse; GO:0033267 (0.12) ! axon part; GO:0045121 (0.11) ! membrane raft; GO:0043229 (0.11) ! intracellular organelle; GO:1902495 (0.10) ! transmembrane transporter complex; GO:0033268 (0.10) ! node of Ranvier; GO:0009925 (0.10) ! basal plasma membrane; GO:0005913 (0.10) ! cell-cell adherens junction; GO:0005622 (0.10) ! intracellular; GO:0044446 (0.09) ! intracellular organelle part; GO:0043231 (0.08) ! intracellular membrane-bounded organelle; GO:0009897 (0.08) ! external side of plasma membrane; GO:0044449 (0.07) ! contractile fiber part; GO:0043235 (0.07) ! receptor complex; GO:0005829 (0.07) ! cytosol; GO:0098802 (0.06) ! plasma membrane receptor complex; GO:0045211 (0.06) ! postsynaptic membrane; GO:0031253 (0.06) ! cell projection membrane; GO:0030426 (0.06) ! growth cone; GO:0016328 (0.06) ! lateral plasma membrane; GO:0016324 (0.06) ! apical plasma membrane; GO:0005925 (0.06) ! focal adhesion; GO:1990060 (0.05) ! maltose transport complex; GO:0097454 (0.05) ! Schwann cell microvillus; GO:0060170 (0.05) ! ciliary membrane; GO:0055052 (0.05) ! ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; GO:0044430 (0.05) ! cytoskeletal part; GO:0044224 (0.05) ! juxtaparanode region of axon; GO:0043194 (0.05) ! axon initial segment; GO:0042101 (0.05) ! T cell receptor complex; GO:0033270 (0.05) ! paranode region of axon; GO:0033010 (0.05) ! paranodal junction; GO:0032584 (0.05) ! growth cone membrane; GO:0031526 (0.05) ! brush border membrane; GO:0030288 (0.05) ! outer membrane-bounded periplasmic space; GO:0030018 (0.05) ! Z disc; GO:0008076 (0.05) ! voltage-gated potassium channel complex; GO:0043232 (0.04) ! intracellular non-membrane-bounded organelle; GO:0031430 (0.04) ! M band; GO:0031012 (0.04) ! extracellular matrix; GO:0036379 (0.03) ! myofilament; GO:0005859 (0.03) ! muscle myosin complex; GO:0005654 (0.03) ! nucleoplasm; GO:0005634 (0.03) ! nucleus; GO:0005623 (0.03) ! cell; GO:0005578 (0.03) ! proteinaceous extracellular matrix; GO:0005865 (0.02) ! striated muscle thin filament; GO:0005811 (0.02) ! lipid particle; GO:0005783 (0.02) ! endoplasmic reticulum; GO:0072562 (0.01) ! blood microparticle; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0044295 (0.01) ! axonal growth cone; GO:0042571 (0.01) ! immunoglobulin complex, circulating; GO:0036056 (0.01) ! filtration diaphragm; GO:0031674 (0.01) ! I band; GO:0031672 (0.01) ! A band; GO:0030133 (0.01) ! transport vesicle; GO:0030017 (0.01) ! sarcomere; GO:0016323 (0.01) ! basolateral plasma membrane; GO:0005875 (0.01) ! microtubule associated complex; GO:0005856 (0.01) ! cytoskeleton; GO:0005794 (0.01) ! Golgi apparatus; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005769 (0.01) ! early endosome; GO:0005739 (0.01) ! mitochondrion GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 2 44899712-44905390 (17q21.31) High: heart muscle (myocytes);smooth muscle (smooth muscle cells);Medium: testis (Leydig cells);cerebral cortex (neuronal cells);skeletal muscle (myocytes);caudate (neuronal cells);Low: cerebellum (Purkinje cells);placenta (trophoblastic cells);oral mucosa (squamous epithelial cells);hippocampus (neuronal cells);thyroid gland (glandular cells);small intestine (glandular cells);colon (glandular cells);gallbladder (glandular cells);esophagus (squamous epithelial cells);duodenum (glandular cells);kidney (cells in tubules);breast (myoepithelial cells); MHLALTTVLLWAWGLQAFEIVEKENIFQRTPCPAFLMFENAAYLADMSFELPCHCKPEEVPAVVWFYQKHLGSSHTKVLTDFDGRVLTEAAQVRVGSDMLTRFSIRMFSLLVFRAQSEDSGLYFCGTRKGDYFYAYDVDIQNSEGMVATFQDKGQEPFADEYYGHLHVFTTFWEWTPCDRCGVRGEQWRIGLCYLQSPDLSPRYLKAVPDVVSCGSRAVPRKLRTKARDHTPEVLVRSCLVPCEKTKTIREGVLAIINYVSKVGSRPWVPQVPIQFHQQRLGHGLIISCPGARPEHAVAWDKDRQHLYRTQYLKGVNRSMRVFIDHGNQLHIRFTQLDDRGIYYCWRQGVLVAGFRLGVTSHGHYPASFSDPETRSAVELTLIGYLLITAVFVTIHFCRCCCYLFHCCPSFSP LRRC37A Leucine-rich repeat-containing protein 37A L37A1_HUMAN (A6NMS7-1) GO:0098772 (0.27) ! molecular function regulator; GO:0030234 (0.26) ! enzyme regulator activity; GO:0004860 (0.25) ! protein kinase inhibitor activity; GO:0005102 (0.16) ! receptor binding; GO:0097367 (0.15) ! carbohydrate derivative binding; GO:0004872 (0.15) ! receptor activity; GO:0005539 (0.14) ! glycosaminoglycan binding; GO:0008201 (0.13) ! heparin binding; GO:0097159 (0.12) ! organic cyclic compound binding; GO:0003824 (0.12) ! catalytic activity; GO:0048495 (0.11) ! Roundabout binding; GO:0038023 (0.11) ! signaling receptor activity; GO:0003676 (0.11) ! nucleic acid binding; GO:0004888 (0.08) ! transmembrane signaling receptor activity; GO:0003723 (0.08) ! RNA binding; GO:0016740 (0.07) ! transferase activity; GO:0044877 (0.05) ! macromolecular complex binding; GO:0016772 (0.05) ! transferase activity, transferring phosphorus-containing groups; GO:0005198 (0.05) ! structural molecule activity; GO:0004930 (0.05) ! G-protein coupled receptor activity; GO:0044822 (0.04) ! poly(A) RNA binding; GO:0032403 (0.04) ! protein complex binding; GO:0016787 (0.04) ! hydrolase activity; GO:0008092 (0.04) ! cytoskeletal protein binding; GO:0004672 (0.04) ! protein kinase activity; GO:0019899 (0.03) ! enzyme binding; GO:0005201 (0.03) ! extracellular matrix structural constituent; GO:0004674 (0.03) ! protein serine/threonine kinase activity; GO:0003779 (0.03) ! actin binding; GO:0003725 (0.03) ! double-stranded RNA binding; GO:0003712 (0.03) ! transcription cofactor activity; GO:0070851 (0.02) ! growth factor receptor binding; GO:0042802 (0.02) ! identical protein binding; GO:0019901 (0.02) ! protein kinase binding; GO:0019838 (0.02) ! growth factor binding; GO:0016788 (0.02) ! hydrolase activity, acting on ester bonds; GO:0008528 (0.02) ! G-protein coupled peptide receptor activity; GO:0008289 (0.02) ! lipid binding; GO:0008190 (0.02) ! eukaryotic initiation factor 4E binding; GO:0008134 (0.02) ! transcription factor binding; GO:0005518 (0.02) ! collagen binding; GO:0003713 (0.02) ! transcription coactivator activity; GO:0003677 (0.02) ! DNA binding; GO:0097493 (0.01) ! structural molecule activity conferring elasticity; GO:0071723 (0.01) ! lipopeptide binding; GO:0070491 (0.01) ! repressing transcription factor binding; GO:0070052 (0.01) ! collagen V binding; GO:0051427 (0.01) ! hormone receptor binding; GO:0051371 (0.01) ! muscle alpha-actinin binding; GO:0051015 (0.01) ! actin filament binding; GO:0050840 (0.01) ! extracellular matrix binding; GO:0050839 (0.01) ! cell adhesion molecule binding; GO:0050431 (0.01) ! transforming growth factor beta binding; GO:0046983 (0.01) ! protein dimerization activity; GO:0045502 (0.01) ! dynein binding; GO:0035663 (0.01) ! Toll-like receptor 2 binding; GO:0030374 (0.01) ! ligand-dependent nuclear receptor transcription coactivator activity; GO:0019904 (0.01) ! protein domain specific binding; GO:0019903 (0.01) ! protein phosphatase binding; GO:0017016 (0.01) ! Ras GTPase binding; GO:0016791 (0.01) ! phosphatase activity; GO:0016500 (0.01) ! protein-hormone receptor activity; GO:0016462 (0.01) ! pyrophosphatase activity; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008022 (0.01) ! protein C-terminus binding; GO:0008017 (0.01) ! microtubule binding; GO:0005543 (0.01) ! phospholipid binding; GO:0005540 (0.01) ! hyaluronic acid binding; GO:0005520 (0.01) ! insulin-like growth factor binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005216 (0.01) ! ion channel activity; GO:0005154 (0.01) ! epidermal growth factor receptor binding; GO:0005149 (0.01) ! interleukin-1 receptor binding; GO:0005030 (0.01) ! neurotrophin receptor activity; GO:0004842 (0.01) ! ubiquitin-protein transferase activity; GO:0004407 (0.01) ! histone deacetylase activity; GO:0004402 (0.01) ! histone acetyltransferase activity; GO:0004252 (0.01) ! serine-type endopeptidase activity; GO:0003727 (0.01) ! single-stranded RNA binding; GO:0003714 (0.01) ! transcription corepressor activity; GO:0003700 (0.01) ! transcription factor activity, sequence-specific DNA binding; GO:0003682 (0.01) ! chromatin binding; GO:0001948 (0.01) ! glycoprotein binding; GO:0001875 (0.01) ! lipopolysaccharide receptor activity; GO:0001530 (0.01) ! lipopolysaccharide binding; GO:0001104 (0.01) ! RNA polymerase II transcription cofactor activity; GO:0000976 (0.01) ! transcription regulatory region sequence-specific DNA binding; GO:0000166 (0.01) ! nucleotide binding GO:0065007 (0.61) ! biological regulation; GO:0050789 (0.59) ! regulation of biological process; GO:0009987 (0.59) ! cellular process; GO:0050794 (0.58) ! regulation of cellular process; GO:0044699 (0.53) ! single-organism process; GO:0044763 (0.47) ! single-organism cellular process; GO:0032502 (0.44) ! developmental process; GO:0007165 (0.44) ! signal transduction; GO:0044767 (0.42) ! single-organism developmental process; GO:0016043 (0.35) ! cellular component organization; GO:0048583 (0.32) ! regulation of response to stimulus; GO:0007166 (0.30) ! cell surface receptor signaling pathway; GO:0019222 (0.29) ! regulation of metabolic process; GO:0009653 (0.29) ! anatomical structure morphogenesis; GO:0031323 (0.28) ! regulation of cellular metabolic process; GO:0080090 (0.27) ! regulation of primary metabolic process; GO:0060255 (0.27) ! regulation of macromolecule metabolic process; GO:0048869 (0.27) ! cellular developmental process; GO:0048523 (0.27) ! negative regulation of cellular process; GO:0023051 (0.25) ! regulation of signaling; GO:0010646 (0.25) ! regulation of cell communication; GO:0065009 (0.24) ! regulation of molecular function; GO:0030030 (0.24) ! cell projection organization; GO:0009966 (0.24) ! regulation of signal transduction; GO:0048858 (0.23) ! cell projection morphogenesis; GO:0050790 (0.22) ! regulation of catalytic activity; GO:0032268 (0.22) ! regulation of cellular protein metabolic process; GO:0031324 (0.22) ! negative regulation of cellular metabolic process; GO:0019220 (0.22) ! regulation of phosphate metabolic process; GO:0010605 (0.22) ! negative regulation of macromolecule metabolic process; GO:0007409 (0.22) ! axonogenesis; GO:1902531 (0.21) ! regulation of intracellular signal transduction; GO:0009968 (0.21) ! negative regulation of signal transduction; GO:0001932 (0.21) ! regulation of protein phosphorylation; GO:0045859 (0.20) ! regulation of protein kinase activity; GO:0042326 (0.20) ! negative regulation of phosphorylation; GO:0031400 (0.20) ! negative regulation of protein modification process; GO:0048518 (0.19) ! positive regulation of biological process; GO:0046426 (0.19) ! negative regulation of JAK-STAT cascade; GO:0019221 (0.19) ! cytokine-mediated signaling pathway; GO:0006469 (0.19) ! negative regulation of protein kinase activity; GO:0051128 (0.16) ! regulation of cellular component organization; GO:0051239 (0.15) ! regulation of multicellular organismal process; GO:0050896 (0.14) ! response to stimulus; GO:2000026 (0.13) ! regulation of multicellular organismal development; GO:0048856 (0.13) ! anatomical structure development; GO:0071704 (0.11) ! organic substance metabolic process; GO:0051960 (0.11) ! regulation of nervous system development; GO:0048584 (0.11) ! positive regulation of response to stimulus; GO:0048522 (0.11) ! positive regulation of cellular process; GO:0045595 (0.11) ! regulation of cell differentiation; GO:0044237 (0.11) ! cellular metabolic process; GO:0022603 (0.11) ! regulation of anatomical structure morphogenesis; GO:0006950 (0.11) ! response to stress; GO:0050770 (0.10) ! regulation of axonogenesis; GO:0048589 (0.10) ! developmental growth; GO:0044238 (0.10) ! primary metabolic process; GO:0043170 (0.10) ! macromolecule metabolic process; GO:0032501 (0.10) ! multicellular organismal process; GO:0002376 (0.10) ! immune system process; GO:0080134 (0.09) ! regulation of response to stress; GO:0048846 (0.09) ! axon extension involved in axon guidance; GO:0044260 (0.09) ! cellular macromolecule metabolic process; GO:0035385 (0.09) ! Roundabout signaling pathway; GO:0009605 (0.09) ! response to external stimulus; GO:0002682 (0.09) ! regulation of immune system process; GO:0051704 (0.08) ! multi-organism process; GO:0050778 (0.08) ! positive regulation of immune response; GO:0045088 (0.08) ! regulation of innate immune response; GO:0043207 (0.08) ! response to external biotic stimulus; GO:0031349 (0.08) ! positive regulation of defense response; GO:0006952 (0.08) ! defense response; GO:0051171 (0.07) ! regulation of nitrogen compound metabolic process; GO:0044707 (0.07) ! single-multicellular organism process; GO:0031326 (0.07) ! regulation of cellular biosynthetic process; GO:0002224 (0.07) ! toll-like receptor signaling pathway; GO:0098542 (0.06) ! defense response to other organism; GO:0065008 (0.06) ! regulation of biological quality; GO:0051179 (0.06) ! localization; GO:0031325 (0.06) ! positive regulation of cellular metabolic process; GO:0019538 (0.06) ! protein metabolic process; GO:0019219 (0.06) ! regulation of nucleobase-containing compound metabolic process; GO:0010556 (0.06) ! regulation of macromolecule biosynthetic process; GO:0010468 (0.06) ! regulation of gene expression; GO:0006996 (0.06) ! organelle organization; GO:2000112 (0.05) ! regulation of cellular macromolecule biosynthetic process; GO:0051716 (0.05) ! cellular response to stimulus; GO:0051252 (0.05) ! regulation of RNA metabolic process; GO:0048513 (0.05) ! animal organ development; GO:0043933 (0.05) ! macromolecular complex subunit organization; GO:0032879 (0.05) ! regulation of localization; GO:0031328 (0.05) ! positive regulation of cellular biosynthetic process; GO:0022607 (0.05) ! cellular component assembly; GO:0010033 (0.05) ! response to organic substance; GO:0006928 (0.05) ! movement of cell or subcellular component; GO:0006810 (0.05) ! transport; GO:0006807 (0.05) ! nitrogen compound metabolic process; GO:0006464 (0.05) ! cellular protein modification process; GO:0090304 (0.04) ! nucleic acid metabolic process; GO:0051049 (0.04) ! regulation of transport; GO:0045935 (0.04) ! positive regulation of nucleobase-containing compound metabolic process; GO:0044702 (0.04) ! single organism reproductive process; GO:0044093 (0.04) ! positive regulation of molecular function; GO:0044087 (0.04) ! regulation of cellular component biogenesis; GO:0033043 (0.04) ! regulation of organelle organization; GO:0023056 (0.04) ! positive regulation of signaling; GO:0010647 (0.04) ! positive regulation of cell communication; GO:0010604 (0.04) ! positive regulation of macromolecule metabolic process; GO:0007411 (0.04) ! axon guidance; GO:0007186 (0.04) ! G-protein coupled receptor signaling pathway; GO:0007010 (0.04) ! cytoskeleton organization; GO:0006355 (0.04) ! regulation of transcription, DNA-templated; GO:0003008 (0.04) ! system process; GO:1902589 (0.03) ! single-organism organelle organization; GO:0070925 (0.03) ! organelle assembly; GO:0051641 (0.03) ! cellular localization; GO:0051241 (0.03) ! negative regulation of multicellular organismal process; GO:0051240 (0.03) ! positive regulation of multicellular organismal process; GO:0051130 (0.03) ! positive regulation of cellular component organization; GO:0048731 (0.03) ! system development; GO:0048646 (0.03) ! anatomical structure formation involved in morphogenesis; GO:0042742 (0.03) ! defense response to bacterium; GO:0040011 (0.03) ! locomotion; GO:0040008 (0.03) ! regulation of growth; GO:0035556 (0.03) ! intracellular signal transduction; GO:0034622 (0.03) ! cellular macromolecular complex assembly; GO:0016070 (0.03) ! RNA metabolic process; GO:0010628 (0.03) ! positive regulation of gene expression; GO:0010557 (0.03) ! positive regulation of macromolecule biosynthetic process; GO:0009967 (0.03) ! positive regulation of signal transduction; GO:0009888 (0.03) ! tissue development; GO:0008104 (0.03) ! protein localization; GO:0007188 (0.03) ! adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0007155 (0.03) ! cell adhesion; GO:0006955 (0.03) ! immune response; GO:0006954 (0.03) ! inflammatory response; GO:0006468 (0.03) ! protein phosphorylation; GO:0006357 (0.03) ! regulation of transcription from RNA polymerase II promoter; GO:1903047 (0.02) ! mitotic cell cycle process; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:0090066 (0.02) ! regulation of anatomical structure size; GO:0071822 (0.02) ! protein complex subunit organization; GO:0071310 (0.02) ! cellular response to organic substance; GO:0071219 (0.02) ! cellular response to molecule of bacterial origin; GO:0051962 (0.02) ! positive regulation of nervous system development; GO:0051607 (0.02) ! defense response to virus; GO:0051270 (0.02) ! regulation of cellular component movement; GO:0051247 (0.02) ! positive regulation of protein metabolic process; GO:0051129 (0.02) ! negative regulation of cellular component organization; GO:0051093 (0.02) ! negative regulation of developmental process; GO:0051050 (0.02) ! positive regulation of transport; GO:0048729 (0.02) ! tissue morphogenesis; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0048468 (0.02) ! cell development; GO:0046907 (0.02) ! intracellular transport; GO:0045944 (0.02) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045937 (0.02) ! positive regulation of phosphate metabolic process; GO:0045926 (0.02) ! negative regulation of growth; GO:0045892 (0.02) ! negative regulation of transcription, DNA-templated; GO:0045087 (0.02) ! innate immune response; GO:0044765 (0.02) ! single-organism transport; GO:0044710 (0.02) ! single-organism metabolic process; GO:0044089 (0.02) ! positive regulation of cellular component biogenesis; GO:0043085 (0.02) ! positive regulation of catalytic activity; GO:0034063 (0.02) ! stress granule assembly; GO:0033993 (0.02) ! response to lipid; GO:0033554 (0.02) ! cellular response to stress; GO:0032101 (0.02) ! regulation of response to external stimulus; GO:0031032 (0.02) ! actomyosin structure organization; GO:0030154 (0.02) ! cell differentiation; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0018193 (0.02) ! peptidyl-amino acid modification; GO:0016477 (0.02) ! cell migration; GO:0016192 (0.02) ! vesicle-mediated transport; GO:0015031 (0.02) ! protein transport; GO:0010941 (0.02) ! regulation of cell death; GO:0010603 (0.02) ! regulation of cytoplasmic mRNA processing body assembly; GO:0009886 (0.02) ! post-embryonic morphogenesis; GO:0009628 (0.02) ! response to abiotic stimulus; GO:0009056 (0.02) ! catabolic process; GO:0007610 (0.02) ! behavior; GO:0007600 (0.02) ! sensory perception; GO:0007423 (0.02) ! sensory organ development; GO:0007275 (0.02) ! multicellular organism development; GO:0007267 (0.02) ! cell-cell signaling; GO:0007189 (0.02) ! adenylate cyclase-activating G-protein coupled receptor signaling pathway; GO:0007015 (0.02) ! actin filament organization; GO:0006397 (0.02) ! mRNA processing; GO:0006325 (0.02) ! chromatin organization; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0001817 (0.02) ! regulation of cytokine production; GO:0001558 (0.02) ! regulation of cell growth; GO:0000226 (0.02) ! microtubule cytoskeleton organization; GO:2000021 (0.01) ! regulation of ion homeostasis; GO:1904064 (0.01) ! positive regulation of cation transmembrane transport; GO:1903706 (0.01) ! regulation of hemopoiesis; GO:1902582 (0.01) ! single-organism intracellular transport; GO:1902275 (0.01) ! regulation of chromatin organization; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:1901565 (0.01) ! organonitrogen compound catabolic process; GO:1901361 (0.01) ! organic cyclic compound catabolic process; GO:1901135 (0.01) ! carbohydrate derivative metabolic process; GO:0098742 (0.01) ! cell-cell adhesion via plasma-membrane adhesion molecules; GO:0090287 (0.01) ! regulation of cellular response to growth factor stimulus; GO:0090263 (0.01) ! positive regulation of canonical Wnt signaling pathway; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0071727 (0.01) ! cellular response to triacyl bacterial lipopeptide; GO:0071726 (0.01) ! cellular response to diacyl bacterial lipopeptide; GO:0071495 (0.01) ! cellular response to endogenous stimulus; GO:0071396 (0.01) ! cellular response to lipid; GO:0071214 (0.01) ! cellular response to abiotic stimulus; GO:0061024 (0.01) ! membrane organization; GO:0060271 (0.01) ! cilium morphogenesis; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051965 (0.01) ! positive regulation of synapse assembly; GO:0051646 (0.01) ! mitochondrion localization; GO:0051345 (0.01) ! positive regulation of hydrolase activity; GO:0051091 (0.01) ! positive regulation of sequence-specific DNA binding transcription factor activity; GO:0050920 (0.01) ! regulation of chemotaxis; GO:0050829 (0.01) ! defense response to Gram-negative bacterium; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0050772 (0.01) ! positive regulation of axonogenesis; GO:0050709 (0.01) ! negative regulation of protein secretion; GO:0050663 (0.01) ! cytokine secretion; GO:0048739 (0.01) ! cardiac muscle fiber development; GO:0048666 (0.01) ! neuron development; GO:0048639 (0.01) ! positive regulation of developmental growth; GO:0048608 (0.01) ! reproductive structure development; GO:0048569 (0.01) ! post-embryonic organ development; GO:0048511 (0.01) ! rhythmic process; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046700 (0.01) ! heterocycle catabolic process; GO:0046579 (0.01) ! positive regulation of Ras protein signal transduction; GO:0046331 (0.01) ! lateral inhibition; GO:0045359 (0.01) ! positive regulation of interferon-beta biosynthetic process; GO:0045356 (0.01) ! positive regulation of interferon-alpha biosynthetic process; GO:0045214 (0.01) ! sarcomere organization; GO:0045078 (0.01) ! positive regulation of interferon-gamma biosynthetic process; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0044719 (0.01) ! regulation of imaginal disc-derived wing size; GO:0044708 (0.01) ! single-organism behavior; GO:0044271 (0.01) ! cellular nitrogen compound biosynthetic process; GO:0044270 (0.01) ! cellular nitrogen compound catabolic process; GO:0044265 (0.01) ! cellular macromolecule catabolic process; GO:0043966 (0.01) ! histone H3 acetylation; GO:0043900 (0.01) ! regulation of multi-organism process; GO:0043410 (0.01) ! positive regulation of MAPK cascade; GO:0043331 (0.01) ! response to dsRNA; GO:0043087 (0.01) ! regulation of GTPase activity; GO:0043068 (0.01) ! positive regulation of programmed cell death; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0042592 (0.01) ! homeostatic process; GO:0042116 (0.01) ! macrophage activation; GO:0042059 (0.01) ! negative regulation of epidermal growth factor receptor signaling pathway; GO:0040023 (0.01) ! establishment of nucleus localization; GO:0040017 (0.01) ! positive regulation of locomotion; GO:0040005 (0.01) ! chitin-based cuticle attachment to epithelium; GO:0035239 (0.01) ! tube morphogenesis; GO:0034248 (0.01) ! regulation of cellular amide metabolic process; GO:0034121 (0.01) ! regulation of toll-like receptor signaling pathway; GO:0033365 (0.01) ! protein localization to organelle; GO:0032956 (0.01) ! regulation of actin cytoskeleton organization; GO:0032757 (0.01) ! positive regulation of interleukin-8 production; GO:0032496 (0.01) ! response to lipopolysaccharide; GO:0032490 (0.01) ! detection of molecule of bacterial origin; GO:0032414 (0.01) ! positive regulation of ion transmembrane transporter activity; GO:0032386 (0.01) ! regulation of intracellular transport; GO:0032103 (0.01) ! positive regulation of response to external stimulus; GO:0032102 (0.01) ! negative regulation of response to external stimulus; GO:0031334 (0.01) ! positive regulation of protein complex assembly; GO:0031290 (0.01) ! retinal ganglion cell axon guidance; GO:0031103 (0.01) ! axon regeneration; GO:0030517 (0.01) ! negative regulation of axon extension; GO:0030336 (0.01) ! negative regulation of cell migration; GO:0030241 (0.01) ! skeletal muscle myosin thick filament assembly; GO:0030240 (0.01) ! skeletal muscle thin filament assembly; GO:0030198 (0.01) ! extracellular matrix organization; GO:0030155 (0.01) ! regulation of cell adhesion; GO:0030100 (0.01) ! regulation of endocytosis; GO:0022411 (0.01) ! cellular component disassembly; GO:0021952 (0.01) ! central nervous system projection neuron axonogenesis; GO:0019439 (0.01) ! aromatic compound catabolic process; GO:0019233 (0.01) ! sensory perception of pain; GO:0016482 (0.01) ! cytosolic transport; GO:0016337 (0.01) ! single organismal cell-cell adhesion; GO:0010959 (0.01) ! regulation of metal ion transport; GO:0010638 (0.01) ! positive regulation of organelle organization; GO:0010631 (0.01) ! epithelial cell migration; GO:0010243 (0.01) ! response to organonitrogen compound; GO:0010035 (0.01) ! response to inorganic substance; GO:0009887 (0.01) ! organ morphogenesis; GO:0009792 (0.01) ! embryo development ending in birth or egg hatching; GO:0009755 (0.01) ! hormone-mediated signaling pathway; GO:0009725 (0.01) ! response to hormone; GO:0009612 (0.01) ! response to mechanical stimulus; GO:0009059 (0.01) ! macromolecule biosynthetic process; GO:0008362 (0.01) ! chitin-based embryonic cuticle biosynthetic process; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008045 (0.01) ! motor neuron axon guidance; GO:0008037 (0.01) ! cell recognition; GO:0007626 (0.01) ! locomotory behavior; GO:0007525 (0.01) ! somatic muscle development; GO:0007522 (0.01) ! visceral muscle development; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007507 (0.01) ! heart development; GO:0007498 (0.01) ! mesoderm development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007475 (0.01) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.01) ! open tracheal system development; GO:0007420 (0.01) ! brain development; GO:0007417 (0.01) ! central nervous system development; GO:0007416 (0.01) ! synapse assembly; GO:0007346 (0.01) ! regulation of mitotic cell cycle; GO:0007283 (0.01) ! spermatogenesis; GO:0007190 (0.01) ! activation of adenylate cyclase activity; GO:0007169 (0.01) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007163 (0.01) ! establishment or maintenance of cell polarity; GO:0006997 (0.01) ! nucleus organization; GO:0006941 (0.01) ! striated muscle contraction; GO:0006935 (0.01) ! chemotaxis; GO:0006897 (0.01) ! endocytosis; GO:0006886 (0.01) ! intracellular protein transport; GO:0006811 (0.01) ! ion transport; GO:0006508 (0.01) ! proteolysis; GO:0006259 (0.01) ! DNA metabolic process; GO:0006082 (0.01) ! organic acid metabolic process; GO:0003013 (0.01) ! circulatory system process; GO:0003002 (0.01) ! regionalization; GO:0002831 (0.01) ! regulation of response to biotic stimulus; GO:0002697 (0.01) ! regulation of immune effector process; GO:0002683 (0.01) ! negative regulation of immune system process; GO:0002121 (0.01) ! inter-male aggressive behavior; GO:0002064 (0.01) ! epithelial cell development; GO:0002009 (0.01) ! morphogenesis of an epithelium; GO:0001818 (0.01) ! negative regulation of cytokine production; GO:0001654 (0.01) ! eye development; GO:0001501 (0.01) ! skeletal system development; GO:0000398 (0.01) ! mRNA splicing, via spliceosome; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter GO:0044464 (0.78) ! cell part; GO:0044424 (0.59) ! intracellular part; GO:0005737 (0.38) ! cytoplasm; GO:0044421 (0.24) ! extracellular region part; GO:0044425 (0.19) ! membrane part; GO:0043226 (0.19) ! organelle; GO:0031012 (0.19) ! extracellular matrix; GO:0005615 (0.18) ! extracellular space; GO:0043229 (0.16) ! intracellular organelle; GO:0005578 (0.16) ! proteinaceous extracellular matrix; GO:0044459 (0.15) ! plasma membrane part; GO:0044444 (0.15) ! cytoplasmic part; GO:0043227 (0.15) ! membrane-bounded organelle; GO:0032991 (0.15) ! macromolecular complex; GO:0031224 (0.15) ! intrinsic component of membrane; GO:0016020 (0.15) ! membrane; GO:0044422 (0.14) ! organelle part; GO:0016021 (0.14) ! integral component of membrane; GO:0044446 (0.13) ! intracellular organelle part; GO:0031226 (0.13) ! intrinsic component of plasma membrane; GO:0043234 (0.12) ! protein complex; GO:0043231 (0.12) ! intracellular membrane-bounded organelle; GO:0005887 (0.12) ! integral component of plasma membrane; GO:0005886 (0.10) ! plasma membrane; GO:0044428 (0.07) ! nuclear part; GO:0005634 (0.07) ! nucleus; GO:0043232 (0.05) ! intracellular non-membrane-bounded organelle; GO:0031988 (0.05) ! membrane-bounded vesicle; GO:0070062 (0.04) ! extracellular exosome; GO:0044430 (0.04) ! cytoskeletal part; GO:1902494 (0.03) ! catalytic complex; GO:0098796 (0.03) ! membrane protein complex; GO:0097458 (0.03) ! neuron part; GO:0044451 (0.03) ! nucleoplasm part; GO:0005654 (0.03) ! nucleoplasm; GO:1990234 (0.02) ! transferase complex; GO:0098797 (0.02) ! plasma membrane protein complex; GO:0098588 (0.02) ! bounding membrane of organelle; GO:0044463 (0.02) ! cell projection part; GO:0044449 (0.02) ! contractile fiber part; GO:0044431 (0.02) ! Golgi apparatus part; GO:0044427 (0.02) ! chromosomal part; GO:0043235 (0.02) ! receptor complex; GO:0042995 (0.02) ! cell projection; GO:0030054 (0.02) ! cell junction; GO:0010494 (0.02) ! cytoplasmic stress granule; GO:0009986 (0.02) ! cell surface; GO:0005829 (0.02) ! cytosol; GO:0005783 (0.02) ! endoplasmic reticulum; GO:0099513 (0.01) ! polymeric cytoskeletal fiber; GO:0098802 (0.01) ! plasma membrane receptor complex; GO:0098791 (0.01) ! Golgi subcompartment; GO:0097060 (0.01) ! synaptic membrane; GO:0070822 (0.01) ! Sin3-type complex; GO:0060076 (0.01) ! excitatory synapse; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0046696 (0.01) ! lipopolysaccharide receptor complex; GO:0046658 (0.01) ! anchored component of plasma membrane; GO:0045121 (0.01) ! membrane raft; GO:0044440 (0.01) ! endosomal part; GO:0044432 (0.01) ! endoplasmic reticulum part; GO:0043025 (0.01) ! neuronal cell body; GO:0042567 (0.01) ! insulin-like growth factor ternary complex; GO:0035097 (0.01) ! histone methyltransferase complex; GO:0033267 (0.01) ! axon part; GO:0031968 (0.01) ! organelle outer membrane; GO:0031967 (0.01) ! organelle envelope; GO:0031430 (0.01) ! M band; GO:0030914 (0.01) ! STAGA complex; GO:0030426 (0.01) ! growth cone; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030135 (0.01) ! coated vesicle; GO:0030133 (0.01) ! transport vesicle; GO:0030018 (0.01) ! Z disc; GO:0016607 (0.01) ! nuclear speck; GO:0016323 (0.01) ! basolateral plasma membrane; GO:0015629 (0.01) ! actin cytoskeleton; GO:0009897 (0.01) ! external side of plasma membrane; GO:0005930 (0.01) ! axoneme; GO:0005925 (0.01) ! focal adhesion; GO:0005911 (0.01) ! cell-cell junction; GO:0005875 (0.01) ! microtubule associated complex; GO:0005865 (0.01) ! striated muscle thin filament; GO:0005859 (0.01) ! muscle myosin complex; GO:0005815 (0.01) ! microtubule organizing center; GO:0005796 (0.01) ! Golgi lumen; GO:0005794 (0.01) ! Golgi apparatus; GO:0005774 (0.01) ! vacuolar membrane; GO:0005768 (0.01) ! endosome; GO:0005739 (0.01) ! mitochondrion; GO:0005694 (0.01) ! chromosome; GO:0005667 (0.01) ! transcription factor complex; GO:0005622 (0.01) ! intracellular; GO:0005576 (0.01) ! extracellular region; GO:0000139 (0.01) ! Golgi membrane GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 46292733-46337794 (17q21.31) High: testis (elongated or late spermatids; round or early spermatids);Low: testis (pachytene spermatocytes; preleptotene spermatocytes); Testis: 2.25; Brain - Cerebellar Hemisphere: 1.21; Pituitary: 1.17; Brain - Cerebellum: 1.05; Cervix - Endocervix: 1.02; Prostate: 1.01; Thyroid: 0.94; Uterus: 0.87; Nerve - Tibial: 0.86; Skin - Not Sun Exposed (Suprapubic): 0.86; Spleen: 0.80; Skin - Sun Exposed (Lower leg): 0.79; Vagina: 0.74; Lung: 0.72; Ovary: 0.72; Bladder: 0.70; Cervix - Ectocervix: 0.67; Colon - Sigmoid: 0.65; Cells - EBV-transformed lymphocytes: 0.61; Esophagus - Gastroesophageal Junction: 0.60; Adipose - Subcutaneous: 0.58; Minor Salivary Gland: 0.57; Breast - Mammary Tissue: 0.57; Artery - Tibial: 0.57; Artery - Coronary: 0.57; Artery - Aorta: 0.56; Small Intestine - Terminal Ileum: 0.56; Esophagus - Muscularis: 0.55; Brain - Cortex: 0.55; Brain - Frontal Cortex (BA9): 0.54; Brain - Nucleus accumbens (basal ganglia): 0.53; Adipose - Visceral (Omentum): 0.50; Esophagus - Mucosa: 0.50; Brain - Caudate (basal ganglia): 0.48; Brain - Anterior cingulate cortex (BA24): 0.48; Colon - Transverse: 0.47; Brain - Spinal cord (cervical c-1): 0.44; Brain - Hypothalamus: 0.43; Brain - Hippocampus: 0.42; Fallopian Tube: 0.41; Brain - Amygdala: 0.40; Stomach: 0.39; Whole Blood: 0.38; Cells - Transformed fibroblasts: 0.38; Adrenal Gland: 0.38; Brain - Putamen (basal ganglia): 0.36; Kidney - Cortex: 0.32; Brain - Substantia nigra: 0.30; Muscle - Skeletal: 0.28; Pancreas: 0.24; Heart - Atrial Appendage: 0.23; Liver: 0.22; Heart - Left Ventricle: 0.12; MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENAAEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGTPSTSSPAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTKVKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSEHFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSRGIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKILNRDPGDSEAPTEEEESEALP LRRC37A2 Leucine-rich repeat-containing protein 37A2 L37A2_HUMAN (A6NM11-1) GO:0098772 (0.27) ! molecular function regulator; GO:0004857 (0.26) ! enzyme inhibitor activity; GO:0004860 (0.25) ! protein kinase inhibitor activity; GO:0097367 (0.16) ! carbohydrate derivative binding; GO:0005102 (0.16) ! receptor binding; GO:0004872 (0.16) ! receptor activity; GO:0005539 (0.14) ! glycosaminoglycan binding; GO:0008201 (0.13) ! heparin binding; GO:0048495 (0.12) ! Roundabout binding; GO:1901363 (0.11) ! heterocyclic compound binding; GO:0097159 (0.11) ! organic cyclic compound binding; GO:0038023 (0.11) ! signaling receptor activity; GO:0003824 (0.11) ! catalytic activity; GO:0003676 (0.10) ! nucleic acid binding; GO:0004888 (0.08) ! transmembrane signaling receptor activity; GO:0003723 (0.08) ! RNA binding; GO:0016740 (0.06) ! transferase activity; GO:0004930 (0.06) ! G-protein coupled receptor activity; GO:0044877 (0.05) ! macromolecular complex binding; GO:0016772 (0.05) ! transferase activity, transferring phosphorus-containing groups; GO:0005198 (0.05) ! structural molecule activity; GO:0032403 (0.04) ! protein complex binding; GO:0016787 (0.04) ! hydrolase activity; GO:0008092 (0.04) ! cytoskeletal protein binding; GO:0004672 (0.04) ! protein kinase activity; GO:0044822 (0.03) ! poly(A) RNA binding; GO:0019899 (0.03) ! enzyme binding; GO:0005201 (0.03) ! extracellular matrix structural constituent; GO:0004674 (0.03) ! protein serine/threonine kinase activity; GO:0003779 (0.03) ! actin binding; GO:0003725 (0.03) ! double-stranded RNA binding; GO:0070851 (0.02) ! growth factor receptor binding; GO:0042802 (0.02) ! identical protein binding; GO:0042277 (0.02) ! peptide binding; GO:0019838 (0.02) ! growth factor binding; GO:0016788 (0.02) ! hydrolase activity, acting on ester bonds; GO:0008528 (0.02) ! G-protein coupled peptide receptor activity; GO:0008289 (0.02) ! lipid binding; GO:0008190 (0.02) ! eukaryotic initiation factor 4E binding; GO:0005518 (0.02) ! collagen binding; GO:0003712 (0.02) ! transcription cofactor activity; GO:0003677 (0.02) ! DNA binding; GO:0097493 (0.01) ! structural molecule activity conferring elasticity; GO:0071723 (0.01) ! lipopeptide binding; GO:0070052 (0.01) ! collagen V binding; GO:0051371 (0.01) ! muscle alpha-actinin binding; GO:0051015 (0.01) ! actin filament binding; GO:0050839 (0.01) ! cell adhesion molecule binding; GO:0050431 (0.01) ! transforming growth factor beta binding; GO:0046983 (0.01) ! protein dimerization activity; GO:0045502 (0.01) ! dynein binding; GO:0044212 (0.01) ! transcription regulatory region DNA binding; GO:0043565 (0.01) ! sequence-specific DNA binding; GO:0035663 (0.01) ! Toll-like receptor 2 binding; GO:0035197 (0.01) ! siRNA binding; GO:0030695 (0.01) ! GTPase regulator activity; GO:0030374 (0.01) ! ligand-dependent nuclear receptor transcription coactivator activity; GO:0019904 (0.01) ! protein domain specific binding; GO:0019902 (0.01) ! phosphatase binding; GO:0019901 (0.01) ! protein kinase binding; GO:0017111 (0.01) ! nucleoside-triphosphatase activity; GO:0016811 (0.01) ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0016791 (0.01) ! phosphatase activity; GO:0016500 (0.01) ! protein-hormone receptor activity; GO:0016247 (0.01) ! channel regulator activity; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008134 (0.01) ! transcription factor binding; GO:0008017 (0.01) ! microtubule binding; GO:0005543 (0.01) ! phospholipid binding; GO:0005540 (0.01) ! hyaluronic acid binding; GO:0005520 (0.01) ! insulin-like growth factor binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005216 (0.01) ! ion channel activity; GO:0005154 (0.01) ! epidermal growth factor receptor binding; GO:0005149 (0.01) ! interleukin-1 receptor binding; GO:0005030 (0.01) ! neurotrophin receptor activity; GO:0004842 (0.01) ! ubiquitin-protein transferase activity; GO:0004826 (0.01) ! phenylalanine-tRNA ligase activity; GO:0004175 (0.01) ! endopeptidase activity; GO:0003727 (0.01) ! single-stranded RNA binding; GO:0003700 (0.01) ! transcription factor activity, sequence-specific DNA binding; GO:0003682 (0.01) ! chromatin binding; GO:0001948 (0.01) ! glycoprotein binding; GO:0001875 (0.01) ! lipopolysaccharide receptor activity; GO:0001530 (0.01) ! lipopolysaccharide binding; GO:0001104 (0.01) ! RNA polymerase II transcription cofactor activity; GO:0000166 (0.01) ! nucleotide binding GO:0065007 (0.61) ! biological regulation; GO:0050789 (0.60) ! regulation of biological process; GO:0009987 (0.59) ! cellular process; GO:0050794 (0.58) ! regulation of cellular process; GO:0044699 (0.53) ! single-organism process; GO:0044763 (0.47) ! single-organism cellular process; GO:0007165 (0.45) ! signal transduction; GO:0032502 (0.44) ! developmental process; GO:0044767 (0.42) ! single-organism developmental process; GO:0016043 (0.35) ! cellular component organization; GO:0048583 (0.32) ! regulation of response to stimulus; GO:0007166 (0.30) ! cell surface receptor signaling pathway; GO:0031323 (0.29) ! regulation of cellular metabolic process; GO:0009653 (0.29) ! anatomical structure morphogenesis; GO:0080090 (0.28) ! regulation of primary metabolic process; GO:0048869 (0.28) ! cellular developmental process; GO:0060255 (0.27) ! regulation of macromolecule metabolic process; GO:0048523 (0.27) ! negative regulation of cellular process; GO:0065009 (0.25) ! regulation of molecular function; GO:0030030 (0.25) ! cell projection organization; GO:0023051 (0.25) ! regulation of signaling; GO:0048858 (0.24) ! cell projection morphogenesis; GO:0009966 (0.24) ! regulation of signal transduction; GO:0051246 (0.23) ! regulation of protein metabolic process; GO:0050790 (0.23) ! regulation of catalytic activity; GO:0019220 (0.23) ! regulation of phosphate metabolic process; GO:0007409 (0.23) ! axonogenesis; GO:1902531 (0.22) ! regulation of intracellular signal transduction; GO:0048585 (0.22) ! negative regulation of response to stimulus; GO:0032268 (0.22) ! regulation of cellular protein metabolic process; GO:0031324 (0.22) ! negative regulation of cellular metabolic process; GO:0010605 (0.22) ! negative regulation of macromolecule metabolic process; GO:0009968 (0.21) ! negative regulation of signal transduction; GO:0001932 (0.21) ! regulation of protein phosphorylation; GO:1902532 (0.20) ! negative regulation of intracellular signal transduction; GO:0006469 (0.20) ! negative regulation of protein kinase activity; GO:0048518 (0.19) ! positive regulation of biological process; GO:0046426 (0.19) ! negative regulation of JAK-STAT cascade; GO:0019221 (0.19) ! cytokine-mediated signaling pathway; GO:0051239 (0.16) ! regulation of multicellular organismal process; GO:0051128 (0.15) ! regulation of cellular component organization; GO:0050896 (0.15) ! response to stimulus; GO:0050793 (0.14) ! regulation of developmental process; GO:2000026 (0.13) ! regulation of multicellular organismal development; GO:0051960 (0.12) ! regulation of nervous system development; GO:0048856 (0.12) ! anatomical structure development; GO:0045595 (0.12) ! regulation of cell differentiation; GO:0050767 (0.11) ! regulation of neurogenesis; GO:0048584 (0.11) ! positive regulation of response to stimulus; GO:0048522 (0.11) ! positive regulation of cellular process; GO:0022603 (0.11) ! regulation of anatomical structure morphogenesis; GO:0008152 (0.11) ! metabolic process; GO:0006950 (0.11) ! response to stress; GO:0002376 (0.11) ! immune system process; GO:0050770 (0.10) ! regulation of axonogenesis; GO:0048589 (0.10) ! developmental growth; GO:0044238 (0.10) ! primary metabolic process; GO:0044237 (0.10) ! cellular metabolic process; GO:0043170 (0.10) ! macromolecule metabolic process; GO:0002682 (0.10) ! regulation of immune system process; GO:0050776 (0.09) ! regulation of immune response; GO:0048846 (0.09) ! axon extension involved in axon guidance; GO:0044260 (0.09) ! cellular macromolecule metabolic process; GO:0035385 (0.09) ! Roundabout signaling pathway; GO:0032501 (0.09) ! multicellular organismal process; GO:0031347 (0.09) ! regulation of defense response; GO:0009605 (0.09) ! response to external stimulus; GO:0006952 (0.09) ! defense response; GO:0002684 (0.09) ! positive regulation of immune system process; GO:0051704 (0.08) ! multi-organism process; GO:0045089 (0.08) ! positive regulation of innate immune response; GO:0043207 (0.08) ! response to external biotic stimulus; GO:0002253 (0.08) ! activation of immune response; GO:0051707 (0.07) ! response to other organism; GO:0051171 (0.07) ! regulation of nitrogen compound metabolic process; GO:0031326 (0.07) ! regulation of cellular biosynthetic process; GO:0002224 (0.07) ! toll-like receptor signaling pathway; GO:0098542 (0.06) ! defense response to other organism; GO:0044707 (0.06) ! single-multicellular organism process; GO:0031325 (0.06) ! positive regulation of cellular metabolic process; GO:0019538 (0.06) ! protein metabolic process; GO:0019219 (0.06) ! regulation of nucleobase-containing compound metabolic process; GO:0006996 (0.06) ! organelle organization; GO:0065008 (0.05) ! regulation of biological quality; GO:0051179 (0.05) ! localization; GO:0032879 (0.05) ! regulation of localization; GO:0031328 (0.05) ! positive regulation of cellular biosynthetic process; GO:0010556 (0.05) ! regulation of macromolecule biosynthetic process; GO:0010468 (0.05) ! regulation of gene expression; GO:0010033 (0.05) ! response to organic substance; GO:0006928 (0.05) ! movement of cell or subcellular component; GO:0006807 (0.05) ! nitrogen compound metabolic process; GO:0006464 (0.05) ! cellular protein modification process; GO:0090304 (0.04) ! nucleic acid metabolic process; GO:0051716 (0.04) ! cellular response to stimulus; GO:0051240 (0.04) ! positive regulation of multicellular organismal process; GO:0048513 (0.04) ! animal organ development; GO:0045935 (0.04) ! positive regulation of nucleobase-containing compound metabolic process; GO:0044702 (0.04) ! single organism reproductive process; GO:0044093 (0.04) ! positive regulation of molecular function; GO:0044087 (0.04) ! regulation of cellular component biogenesis; GO:0043933 (0.04) ! macromolecular complex subunit organization; GO:0022607 (0.04) ! cellular component assembly; GO:0010604 (0.04) ! positive regulation of macromolecule metabolic process; GO:0007411 (0.04) ! axon guidance; GO:0007186 (0.04) ! G-protein coupled receptor signaling pathway; GO:0006810 (0.04) ! transport; GO:0006355 (0.04) ! regulation of transcription, DNA-templated; GO:0003008 (0.04) ! system process; GO:1902589 (0.03) ! single-organism organelle organization; GO:0051641 (0.03) ! cellular localization; GO:0051241 (0.03) ! negative regulation of multicellular organismal process; GO:0051130 (0.03) ! positive regulation of cellular component organization; GO:0051049 (0.03) ! regulation of transport; GO:0048731 (0.03) ! system development; GO:0042742 (0.03) ! defense response to bacterium; GO:0040011 (0.03) ! locomotion; GO:0040008 (0.03) ! regulation of growth; GO:0034622 (0.03) ! cellular macromolecular complex assembly; GO:0033043 (0.03) ! regulation of organelle organization; GO:0016070 (0.03) ! RNA metabolic process; GO:0010557 (0.03) ! positive regulation of macromolecule biosynthetic process; GO:0009967 (0.03) ! positive regulation of signal transduction; GO:0009888 (0.03) ! tissue development; GO:0007188 (0.03) ! adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0007155 (0.03) ! cell adhesion; GO:0007010 (0.03) ! cytoskeleton organization; GO:0006955 (0.03) ! immune response; GO:0006954 (0.03) ! inflammatory response; GO:0006468 (0.03) ! protein phosphorylation; GO:0006357 (0.03) ! regulation of transcription from RNA polymerase II promoter; GO:0002237 (0.03) ! response to molecule of bacterial origin; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:1902115 (0.02) ! regulation of organelle assembly; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:1901698 (0.02) ! response to nitrogen compound; GO:0090066 (0.02) ! regulation of anatomical structure size; GO:0071822 (0.02) ! protein complex subunit organization; GO:0071702 (0.02) ! organic substance transport; GO:0071310 (0.02) ! cellular response to organic substance; GO:0070925 (0.02) ! organelle assembly; GO:0051962 (0.02) ! positive regulation of nervous system development; GO:0051607 (0.02) ! defense response to virus; GO:0051247 (0.02) ! positive regulation of protein metabolic process; GO:0051172 (0.02) ! negative regulation of nitrogen compound metabolic process; GO:0051129 (0.02) ! negative regulation of cellular component organization; GO:0051093 (0.02) ! negative regulation of developmental process; GO:0051050 (0.02) ! positive regulation of transport; GO:0048729 (0.02) ! tissue morphogenesis; GO:0048646 (0.02) ! anatomical structure formation involved in morphogenesis; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0048468 (0.02) ! cell development; GO:0046907 (0.02) ! intracellular transport; GO:0045944 (0.02) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045087 (0.02) ! innate immune response; GO:0044765 (0.02) ! single-organism transport; GO:0044710 (0.02) ! single-organism metabolic process; GO:0044089 (0.02) ! positive regulation of cellular component biogenesis; GO:0042127 (0.02) ! regulation of cell proliferation; GO:0035556 (0.02) ! intracellular signal transduction; GO:0034765 (0.02) ! regulation of ion transmembrane transport; GO:0033993 (0.02) ! response to lipid; GO:0033554 (0.02) ! cellular response to stress; GO:0032101 (0.02) ! regulation of response to external stimulus; GO:0031327 (0.02) ! negative regulation of cellular biosynthetic process; GO:0031032 (0.02) ! actomyosin structure organization; GO:0030308 (0.02) ! negative regulation of cell growth; GO:0030154 (0.02) ! cell differentiation; GO:0022618 (0.02) ! ribonucleoprotein complex assembly; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0022402 (0.02) ! cell cycle process; GO:0016477 (0.02) ! cell migration; GO:0014070 (0.02) ! response to organic cyclic compound; GO:0010941 (0.02) ! regulation of cell death; GO:0010629 (0.02) ! negative regulation of gene expression; GO:0010558 (0.02) ! negative regulation of macromolecule biosynthetic process; GO:0009886 (0.02) ! post-embryonic morphogenesis; GO:0009755 (0.02) ! hormone-mediated signaling pathway; GO:0009628 (0.02) ! response to abiotic stimulus; GO:0009056 (0.02) ! catabolic process; GO:0008104 (0.02) ! protein localization; GO:0007610 (0.02) ! behavior; GO:0007600 (0.02) ! sensory perception; GO:0007275 (0.02) ! multicellular organism development; GO:0007267 (0.02) ! cell-cell signaling; GO:0007190 (0.02) ! activation of adenylate cyclase activity; GO:0007189 (0.02) ! adenylate cyclase-activating G-protein coupled receptor signaling pathway; GO:0007017 (0.02) ! microtubule-based process; GO:0006397 (0.02) ! mRNA processing; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0001817 (0.02) ! regulation of cytokine production; GO:2000651 (0.01) ! positive regulation of sodium ion transmembrane transporter activity; GO:2000021 (0.01) ! regulation of ion homeostasis; GO:1904950 (0.01) ! negative regulation of establishment of protein localization; GO:1903827 (0.01) ! regulation of cellular protein localization; GO:1903706 (0.01) ! regulation of hemopoiesis; GO:1903530 (0.01) ! regulation of secretion by cell; GO:1903047 (0.01) ! mitotic cell cycle process; GO:1902580 (0.01) ! single-organism cellular localization; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:1901565 (0.01) ! organonitrogen compound catabolic process; GO:1901361 (0.01) ! organic cyclic compound catabolic process; GO:1901135 (0.01) ! carbohydrate derivative metabolic process; GO:0090287 (0.01) ! regulation of cellular response to growth factor stimulus; GO:0090263 (0.01) ! positive regulation of canonical Wnt signaling pathway; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0072593 (0.01) ! reactive oxygen species metabolic process; GO:0071727 (0.01) ! cellular response to triacyl bacterial lipopeptide; GO:0071726 (0.01) ! cellular response to diacyl bacterial lipopeptide; GO:0071495 (0.01) ! cellular response to endogenous stimulus; GO:0071396 (0.01) ! cellular response to lipid; GO:0071214 (0.01) ! cellular response to abiotic stimulus; GO:0061061 (0.01) ! muscle structure development; GO:0061024 (0.01) ! membrane organization; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051965 (0.01) ! positive regulation of synapse assembly; GO:0051705 (0.01) ! multi-organism behavior; GO:0051656 (0.01) ! establishment of organelle localization; GO:0051493 (0.01) ! regulation of cytoskeleton organization; GO:0051223 (0.01) ! regulation of protein transport; GO:0051091 (0.01) ! positive regulation of sequence-specific DNA binding transcription factor activity; GO:0051051 (0.01) ! negative regulation of transport; GO:0050920 (0.01) ! regulation of chemotaxis; GO:0050829 (0.01) ! defense response to Gram-negative bacterium; GO:0050772 (0.01) ! positive regulation of axonogenesis; GO:0050663 (0.01) ! cytokine secretion; GO:0048739 (0.01) ! cardiac muscle fiber development; GO:0048666 (0.01) ! neuron development; GO:0048608 (0.01) ! reproductive structure development; GO:0048511 (0.01) ! rhythmic process; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046700 (0.01) ! heterocycle catabolic process; GO:0046331 (0.01) ! lateral inhibition; GO:0045927 (0.01) ! positive regulation of growth; GO:0045359 (0.01) ! positive regulation of interferon-beta biosynthetic process; GO:0045356 (0.01) ! positive regulation of interferon-alpha biosynthetic process; GO:0045214 (0.01) ! sarcomere organization; GO:0045078 (0.01) ! positive regulation of interferon-gamma biosynthetic process; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0044719 (0.01) ! regulation of imaginal disc-derived wing size; GO:0044708 (0.01) ! single-organism behavior; GO:0044270 (0.01) ! cellular nitrogen compound catabolic process; GO:0044265 (0.01) ! cellular macromolecule catabolic process; GO:0043900 (0.01) ! regulation of multi-organism process; GO:0043410 (0.01) ! positive regulation of MAPK cascade; GO:0043331 (0.01) ! response to dsRNA; GO:0043122 (0.01) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043087 (0.01) ! regulation of GTPase activity; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0042592 (0.01) ! homeostatic process; GO:0042116 (0.01) ! macrophage activation; GO:0042058 (0.01) ! regulation of epidermal growth factor receptor signaling pathway; GO:0040017 (0.01) ! positive regulation of locomotion; GO:0040005 (0.01) ! chitin-based cuticle attachment to epithelium; GO:0035303 (0.01) ! regulation of dephosphorylation; GO:0035239 (0.01) ! tube morphogenesis; GO:0034660 (0.01) ! ncRNA metabolic process; GO:0034645 (0.01) ! cellular macromolecule biosynthetic process; GO:0034248 (0.01) ! regulation of cellular amide metabolic process; GO:0034154 (0.01) ! toll-like receptor 7 signaling pathway; GO:0034121 (0.01) ! regulation of toll-like receptor signaling pathway; GO:0034063 (0.01) ! stress granule assembly; GO:0033365 (0.01) ! protein localization to organelle; GO:0032970 (0.01) ! regulation of actin filament-based process; GO:0032774 (0.01) ! RNA biosynthetic process; GO:0032757 (0.01) ! positive regulation of interleukin-8 production; GO:0032496 (0.01) ! response to lipopolysaccharide; GO:0032490 (0.01) ! detection of molecule of bacterial origin; GO:0032386 (0.01) ! regulation of intracellular transport; GO:0032103 (0.01) ! positive regulation of response to external stimulus; GO:0032102 (0.01) ! negative regulation of response to external stimulus; GO:0031334 (0.01) ! positive regulation of protein complex assembly; GO:0031290 (0.01) ! retinal ganglion cell axon guidance; GO:0031103 (0.01) ! axon regeneration; GO:0030517 (0.01) ! negative regulation of axon extension; GO:0030336 (0.01) ! negative regulation of cell migration; GO:0030241 (0.01) ! skeletal muscle myosin thick filament assembly; GO:0030240 (0.01) ! skeletal muscle thin filament assembly; GO:0030198 (0.01) ! extracellular matrix organization; GO:0030155 (0.01) ! regulation of cell adhesion; GO:0030100 (0.01) ! regulation of endocytosis; GO:0022411 (0.01) ! cellular component disassembly; GO:0021952 (0.01) ! central nervous system projection neuron axonogenesis; GO:0019752 (0.01) ! carboxylic acid metabolic process; GO:0019439 (0.01) ! aromatic compound catabolic process; GO:0019233 (0.01) ! sensory perception of pain; GO:0018205 (0.01) ! peptidyl-lysine modification; GO:0016570 (0.01) ! histone modification; GO:0016482 (0.01) ! cytosolic transport; GO:0016337 (0.01) ! single organismal cell-cell adhesion; GO:0010638 (0.01) ! positive regulation of organelle organization; GO:0010631 (0.01) ! epithelial cell migration; GO:0010603 (0.01) ! regulation of cytoplasmic mRNA processing body assembly; GO:0010243 (0.01) ! response to organonitrogen compound; GO:0010035 (0.01) ! response to inorganic substance; GO:0009887 (0.01) ! organ morphogenesis; GO:0009792 (0.01) ! embryo development ending in birth or egg hatching; GO:0009725 (0.01) ! response to hormone; GO:0009612 (0.01) ! response to mechanical stimulus; GO:0009416 (0.01) ! response to light stimulus; GO:0008362 (0.01) ! chitin-based embryonic cuticle biosynthetic process; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008219 (0.01) ! cell death; GO:0008045 (0.01) ! motor neuron axon guidance; GO:0008037 (0.01) ! cell recognition; GO:0007626 (0.01) ! locomotory behavior; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007498 (0.01) ! mesoderm development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007475 (0.01) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.01) ! open tracheal system development; GO:0007420 (0.01) ! brain development; GO:0007417 (0.01) ! central nervous system development; GO:0007416 (0.01) ! synapse assembly; GO:0007346 (0.01) ! regulation of mitotic cell cycle; GO:0007283 (0.01) ! spermatogenesis; GO:0007169 (0.01) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007156 (0.01) ! homophilic cell adhesion via plasma membrane adhesion molecules; GO:0006941 (0.01) ! striated muscle contraction; GO:0006935 (0.01) ! chemotaxis; GO:0006897 (0.01) ! endocytosis; GO:0006886 (0.01) ! intracellular protein transport; GO:0006820 (0.01) ! anion transport; GO:0006508 (0.01) ! proteolysis; GO:0003013 (0.01) ! circulatory system process; GO:0003002 (0.01) ! regionalization; GO:0002831 (0.01) ! regulation of response to biotic stimulus; GO:0002700 (0.01) ! regulation of production of molecular mediator of immune response; GO:0002683 (0.01) ! negative regulation of immune system process; GO:0002009 (0.01) ! morphogenesis of an epithelium; GO:0001818 (0.01) ! negative regulation of cytokine production; GO:0001654 (0.01) ! eye development; GO:0001501 (0.01) ! skeletal system development; GO:0001101 (0.01) ! response to acid chemical; GO:0000398 (0.01) ! mRNA splicing, via spliceosome; GO:0000226 (0.01) ! microtubule cytoskeleton organization; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter GO:0044464 (0.78) ! cell part; GO:0044424 (0.58) ! intracellular part; GO:0005737 (0.37) ! cytoplasm; GO:0044421 (0.24) ! extracellular region part; GO:0044425 (0.19) ! membrane part; GO:0043226 (0.19) ! organelle; GO:0031012 (0.19) ! extracellular matrix; GO:0005615 (0.18) ! extracellular space; GO:0005578 (0.17) ! proteinaceous extracellular matrix; GO:0044459 (0.16) ! plasma membrane part; GO:0043229 (0.16) ! intracellular organelle; GO:0044444 (0.15) ! cytoplasmic part; GO:0043227 (0.15) ! membrane-bounded organelle; GO:0031224 (0.15) ! intrinsic component of membrane; GO:0016020 (0.15) ! membrane; GO:0032991 (0.14) ! macromolecular complex; GO:0031226 (0.14) ! intrinsic component of plasma membrane; GO:0016021 (0.14) ! integral component of membrane; GO:0044422 (0.13) ! organelle part; GO:0044446 (0.12) ! intracellular organelle part; GO:0043231 (0.12) ! intracellular membrane-bounded organelle; GO:0005887 (0.12) ! integral component of plasma membrane; GO:0043234 (0.11) ! protein complex; GO:0005886 (0.11) ! plasma membrane; GO:0005634 (0.07) ! nucleus; GO:0044428 (0.06) ! nuclear part; GO:0031988 (0.05) ! membrane-bounded vesicle; GO:0070062 (0.04) ! extracellular exosome; GO:0044430 (0.04) ! cytoskeletal part; GO:0043232 (0.04) ! intracellular non-membrane-bounded organelle; GO:1902494 (0.03) ! catalytic complex; GO:0098796 (0.03) ! membrane protein complex; GO:0097458 (0.03) ! neuron part; GO:0005654 (0.03) ! nucleoplasm; GO:0098797 (0.02) ! plasma membrane protein complex; GO:0098590 (0.02) ! plasma membrane region; GO:0098588 (0.02) ! bounding membrane of organelle; GO:0044463 (0.02) ! cell projection part; GO:0044451 (0.02) ! nucleoplasm part; GO:0044449 (0.02) ! contractile fiber part; GO:0044431 (0.02) ! Golgi apparatus part; GO:0043235 (0.02) ! receptor complex; GO:0043005 (0.02) ! neuron projection; GO:0030054 (0.02) ! cell junction; GO:0010494 (0.02) ! cytoplasmic stress granule; GO:0009986 (0.02) ! cell surface; GO:0005829 (0.02) ! cytosol; GO:0005783 (0.02) ! endoplasmic reticulum; GO:0005576 (0.02) ! extracellular region; GO:0099513 (0.01) ! polymeric cytoskeletal fiber; GO:0098802 (0.01) ! plasma membrane receptor complex; GO:0098791 (0.01) ! Golgi subcompartment; GO:0098552 (0.01) ! side of membrane; GO:0097060 (0.01) ! synaptic membrane; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0046696 (0.01) ! lipopolysaccharide receptor complex; GO:0045202 (0.01) ! synapse; GO:0045121 (0.01) ! membrane raft; GO:0044454 (0.01) ! nuclear chromosome part; GO:0044432 (0.01) ! endoplasmic reticulum part; GO:0043025 (0.01) ! neuronal cell body; GO:0042567 (0.01) ! insulin-like growth factor ternary complex; GO:0035097 (0.01) ! histone methyltransferase complex; GO:0034702 (0.01) ! ion channel complex; GO:0033267 (0.01) ! axon part; GO:0031430 (0.01) ! M band; GO:0031225 (0.01) ! anchored component of membrane; GO:0030426 (0.01) ! growth cone; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030135 (0.01) ! coated vesicle; GO:0030133 (0.01) ! transport vesicle; GO:0030018 (0.01) ! Z disc; GO:0016607 (0.01) ! nuclear speck; GO:0016323 (0.01) ! basolateral plasma membrane; GO:0015629 (0.01) ! actin cytoskeleton; GO:0005930 (0.01) ! axoneme; GO:0005924 (0.01) ! cell-substrate adherens junction; GO:0005911 (0.01) ! cell-cell junction; GO:0005875 (0.01) ! microtubule associated complex; GO:0005865 (0.01) ! striated muscle thin filament; GO:0005859 (0.01) ! muscle myosin complex; GO:0005796 (0.01) ! Golgi lumen; GO:0005794 (0.01) ! Golgi apparatus; GO:0005774 (0.01) ! vacuolar membrane; GO:0005768 (0.01) ! endosome; GO:0005739 (0.01) ! mitochondrion; GO:0005694 (0.01) ! chromosome; GO:0005681 (0.01) ! spliceosomal complex; GO:0005622 (0.01) ! intracellular; GO:0000139 (0.01) ! Golgi membrane GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 46511511-46555650 (17q21.31) High: testis (elongated or late spermatids; round or early spermatids);Low: testis (pachytene spermatocytes; preleptotene spermatocytes); Testis: 12.15; Pituitary: 7.56; Brain - Cerebellar Hemisphere: 7.45; Brain - Cerebellum: 7.00; Prostate: 5.92; Skin - Not Sun Exposed (Suprapubic): 5.70; Thyroid: 5.67; Uterus: 5.59; Skin - Sun Exposed (Lower leg): 5.47; Nerve - Tibial: 5.36; Vagina: 5.28; Cervix - Ectocervix: 5.08; Ovary: 5.00; Bladder: 4.96; Spleen: 4.55; Cervix - Endocervix: 4.54; Lung: 4.52; Colon - Sigmoid: 3.93; Artery - Aorta: 3.72; Breast - Mammary Tissue: 3.70; Brain - Cortex: 3.62; Esophagus - Gastroesophageal Junction: 3.62; Adipose - Subcutaneous: 3.60; Artery - Tibial: 3.59; Cells - EBV-transformed lymphocytes: 3.58; Artery - Coronary: 3.57; Minor Salivary Gland: 3.55; Brain - Frontal Cortex (BA9): 3.44; Esophagus - Muscularis: 3.38; Small Intestine - Terminal Ileum: 3.32; Esophagus - Mucosa: 3.15; Brain - Nucleus accumbens (basal ganglia): 3.11; Adipose - Visceral (Omentum): 3.10; Fallopian Tube: 3.07; Brain - Spinal cord (cervical c-1): 2.92; Colon - Transverse: 2.83; Brain - Hypothalamus: 2.68; Adrenal Gland: 2.54; Brain - Caudate (basal ganglia): 2.54; Whole Blood: 2.48; Brain - Hippocampus: 2.48; Cells - Transformed fibroblasts: 2.48; Stomach: 2.37; Brain - Anterior cingulate cortex (BA24): 2.24; Brain - Amygdala: 2.17; Muscle - Skeletal: 2.01; Brain - Substantia nigra: 1.83; Brain - Putamen (basal ganglia): 1.78; Kidney - Cortex: 1.77; Pancreas: 1.50; Heart - Atrial Appendage: 1.45; Liver: 1.20; Heart - Left Ventricle: 0.84; MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENAAEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPKVKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSEHFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSRGIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKILNRDPGDSEAPTEEEESEALP PRR15L Proline-rich protein 15-like protein PR15L_HUMAN (Q9BU68-1) GO:0044877 (0.31) ! macromolecular complex binding; GO:0005524 (0.31) ! ATP binding; GO:0004672 (0.31) ! protein kinase activity GO:0018108 (0.42) ! peptidyl-tyrosine phosphorylation; GO:0008283 (0.42) ! cell proliferation; GO:0006955 (0.42) ! immune response; GO:0006952 (0.42) ! defense response; GO:2001236 (0.31) ! regulation of extrinsic apoptotic signaling pathway; GO:2001234 (0.31) ! negative regulation of apoptotic signaling pathway; GO:0043068 (0.31) ! positive regulation of programmed cell death; GO:0022610 (0.31) ! biological adhesion GO:0044464 (0.95) ! cell part; GO:0044424 (0.89) ! intracellular part; GO:0005737 (0.84) ! cytoplasm; GO:0016020 (0.74) ! membrane; GO:0044425 (0.68) ! membrane part; GO:0044444 (0.63) ! cytoplasmic part; GO:0044459 (0.58) ! plasma membrane part; GO:0043226 (0.58) ! organelle; GO:0005829 (0.58) ! cytosol; GO:0043227 (0.53) ! membrane-bounded organelle; GO:0043231 (0.47) ! intracellular membrane-bounded organelle; GO:0098590 (0.37) ! plasma membrane region; GO:0005886 (0.37) ! plasma membrane; GO:0044446 (0.32) ! intracellular organelle part; GO:0043234 (0.32) ! protein complex; GO:0005634 (0.32) ! nucleus; GO:1902494 (0.26) ! catalytic complex; GO:1902911 (0.21) ! protein kinase complex; GO:0044421 (0.21) ! extracellular region part; GO:0031988 (0.21) ! membrane-bounded vesicle; GO:0016021 (0.21) ! integral component of membrane; GO:0032587 (0.16) ! ruffle membrane; GO:0031588 (0.16) ! nucleotide-activated protein kinase complex; GO:0031234 (0.16) ! extrinsic component of cytoplasmic side of plasma membrane; GO:0016324 (0.16) ! apical plasma membrane; GO:0005911 (0.16) ! cell-cell junction; GO:0005773 (0.16) ! vacuole; GO:0005654 (0.16) ! nucleoplasm; GO:0005615 (0.16) ! extracellular space; GO:0098796 (0.11) ! membrane protein complex; GO:0097458 (0.11) ! neuron part; GO:0070062 (0.11) ! extracellular exosome; GO:0045121 (0.11) ! membrane raft; GO:0043235 (0.11) ! receptor complex; GO:0042995 (0.11) ! cell projection; GO:0031090 (0.11) ! organelle membrane; GO:0030141 (0.11) ! secretory granule; GO:0005887 (0.11) ! integral component of plasma membrane; GO:0005768 (0.11) ! endosome; GO:0005764 (0.11) ! lysosome; GO:0005739 (0.11) ! mitochondrion; GO:0005622 (0.11) ! intracellular; GO:1990604 (0.05) ! IRE1-TRAF2-ASK1 complex; GO:0097342 (0.05) ! ripoptosome; GO:0048471 (0.05) ! perinuclear region of cytoplasm; GO:0043005 (0.05) ! neuron projection; GO:0042629 (0.05) ! mast cell granule; GO:0032593 (0.05) ! insulin-responsive compartment; GO:0031264 (0.05) ! death-inducing signaling complex; GO:0016323 (0.05) ! basolateral plasma membrane; GO:0016028 (0.05) ! rhabdomere; GO:0014069 (0.05) ! postsynaptic density; GO:0010008 (0.05) ! endosome membrane; GO:0009986 (0.05) ! cell surface; GO:0009898 (0.05) ! cytoplasmic side of plasma membrane; GO:0009897 (0.05) ! external side of plasma membrane; GO:0005938 (0.05) ! cell cortex; GO:0005913 (0.05) ! cell-cell adherens junction; GO:0005901 (0.05) ! caveola; GO:0005884 (0.05) ! actin filament; GO:0005856 (0.05) ! cytoskeleton; GO:0005783 (0.05) ! endoplasmic reticulum; GO:0005770 (0.05) ! late endosome; GO:0005769 (0.05) ! early endosome; GO:0005743 (0.05) ! mitochondrial inner membrane; GO:0005576 (0.05) ! extracellular region; GO:0001750 (0.05) ! photoreceptor outer segment; GO:0001669 (0.05) ! acrosomal vesicle 1 47951967-47957878 (17q21.32) High: cerebellum (Purkinje cells);lymph node (non-germinal center cells);small intestine (glandular cells);placenta (decidual cells);seminal vesicle (glandular cells);bone marrow (hematopoietic cells);bronchus (respiratory epithelial cells);tonsil (non-germinal center cells);testis (Leydig cells);endometrium 2 (glandular cells);appendix (glandular cells);colon (endothelial cells; glandular cells);gallbladder (glandular cells);stomach 2 (glandular cells);nasopharynx (respiratory epithelial cells);lung (macrophages);rectum (glandular cells);skin 2 (epidermal cells);kidney (cells in glomeruli; cells in tubules);duodenum (glandular cells);Medium: stomach 1 (glandular cells);colon (peripheral nerve/ganglion);smooth muscle (smooth muscle cells);testis (cells in seminiferous ducts);tonsil (germinal center cells);epididymis (glandular cells);adrenal gland (glandular cells);endometrium 1 (glandular cells);thyroid gland (glandular cells);heart muscle (myocytes);cerebral cortex (endothelial cells);lymph node (germinal center cells);parathyroid gland (glandular cells);skeletal muscle (myocytes);urinary bladder (urothelial cells);appendix (lymphoid tissue);liver (bile duct cells);prostate (glandular cells);pancreas (exocrine glandular cells; islets of Langerhans);placenta (trophoblastic cells);fallopian tube (glandular cells);spleen (cells in red pulp);soft tissue 1 (adipocytes; fibroblasts);soft tissue 2 (adipocytes; fibroblasts);ovary (follicle cells; ovarian stroma cells);oral mucosa (squamous epithelial cells);skin 1 (fibroblasts; keratinocytes; Langerhans; melanocytes);breast (glandular cells; myoepithelial cells);Low: cerebellum (cells in granular layer; cells in molecular layer);hippocampus (glial cells; neuronal cells);caudate (glial cells);spleen (cells in white pulp);soft tissue 1 (peripheral nerve);soft tissue 2 (peripheral nerve);tonsil (squamous epithelial cells);endometrium 2 (cells in endometrial stroma);salivary gland (glandular cells);lung (pneumocytes);breast (adipocytes);esophagus (squamous epithelial cells);cerebral cortex (glial cells; neuronal cells; neuropil);cervix, uterine (glandular cells; squamous epithelial cells); Stomach: 125.00; Thyroid: 107.95; Small Intestine - Terminal Ileum: 100.50; Colon - Transverse: 100.50; Minor Salivary Gland: 84.31; Pancreas: 72.31; Lung: 42.94; Prostate: 30.08; Kidney - Cortex: 27.38; Esophagus - Mucosa: 17.34; Breast - Mammary Tissue: 15.47; Skin - Sun Exposed (Lower leg): 14.59; Pituitary: 13.06; Skin - Not Sun Exposed (Suprapubic): 9.46; Vagina: 9.20; Bladder: 6.10; Testis: 5.57; Fallopian Tube: 4.72; Adipose - Visceral (Omentum): 1.17; Liver: 0.97; Colon - Sigmoid: 0.56; Cervix - Endocervix: 0.44; Cervix - Ectocervix: 0.30; Ovary: 0.29; Brain - Cerebellum: 0.29; Cells - EBV-transformed lymphocytes: 0.26; Uterus: 0.25; Cells - Transformed fibroblasts: 0.23; Brain - Cerebellar Hemisphere: 0.21; Nerve - Tibial: 0.20; Esophagus - Gastroesophageal Junction: 0.19; Esophagus - Muscularis: 0.19; Artery - Aorta: 0.19; Artery - Coronary: 0.17; Spleen: 0.15; Artery - Tibial: 0.15; Adrenal Gland: 0.13; Adipose - Subcutaneous: 0.12; Heart - Atrial Appendage: 0.12; Brain - Nucleus accumbens (basal ganglia): 0.11; Brain - Cortex: 0.11; Brain - Frontal Cortex (BA9): 0.10; Brain - Spinal cord (cervical c-1): 0.10; Brain - Caudate (basal ganglia): 0.09; Brain - Hypothalamus: 0.09; Brain - Putamen (basal ganglia): 0.08; Muscle - Skeletal: 0.08; Brain - Substantia nigra: 0.07; Brain - Anterior cingulate cortex (BA24): 0.07; Whole Blood: 0.07; Brain - Hippocampus: 0.07; Brain - Amygdala: 0.06; Heart - Left Ventricle: 0.05; MTTEIGWWKLTFLRKKKSTPKVLYEIPDTYAQTEGDAEPPRPDAGGPNSDFNTRLEKIVDKSTKGKHVKVSNSGRFKEKKKVRATLAENPNLFDDHEEGRSSK FAM117A FAM117A F117A_HUMAN (Q9C073-1) GO:0022891 (0.51) ! substrate-specific transmembrane transporter activity; GO:0005459 (0.40) ! UDP-galactose transmembrane transporter activity; GO:0003824 (0.23) ! catalytic activity; GO:0072341 (0.17) ! modified amino acid binding; GO:0033218 (0.17) ! amide binding; GO:0019842 (0.17) ! vitamin binding; GO:0005261 (0.10) ! cation channel activity; GO:0022843 (0.09) ! voltage-gated cation channel activity; GO:0005262 (0.09) ! calcium channel activity; GO:0005245 (0.08) ! voltage-gated calcium channel activity; GO:0016740 (0.06) ! transferase activity; GO:0008092 (0.06) ! cytoskeletal protein binding; GO:0016772 (0.05) ! transferase activity, transferring phosphorus-containing groups; GO:0008331 (0.05) ! high voltage-gated calcium channel activity; GO:0008332 (0.04) ! low voltage-gated calcium channel activity; GO:0008190 (0.04) ! eukaryotic initiation factor 4E binding; GO:0008017 (0.04) ! microtubule binding; GO:0003779 (0.04) ! actin binding; GO:0001055 (0.04) ! RNA polymerase II activity; GO:0098772 (0.03) ! molecular function regulator; GO:0097110 (0.03) ! scaffold protein binding; GO:0019899 (0.03) ! enzyme binding; GO:0016787 (0.03) ! hydrolase activity; GO:0003676 (0.03) ! nucleic acid binding; GO:0044877 (0.02) ! macromolecular complex binding; GO:0017016 (0.02) ! Ras GTPase binding; GO:0016788 (0.02) ! hydrolase activity, acting on ester bonds; GO:0005198 (0.02) ! structural molecule activity; GO:0005085 (0.02) ! guanyl-nucleotide exchange factor activity; GO:0003723 (0.02) ! RNA binding; GO:0001104 (0.02) ! RNA polymerase II transcription cofactor activity; GO:0052689 (0.01) ! carboxylic ester hydrolase activity; GO:0050839 (0.01) ! cell adhesion molecule binding; GO:0046983 (0.01) ! protein dimerization activity; GO:0044822 (0.01) ! poly(A) RNA binding; GO:0044325 (0.01) ! ion channel binding; GO:0044212 (0.01) ! transcription regulatory region DNA binding; GO:0034595 (0.01) ! phosphatidylinositol phosphate 5-phosphatase activity; GO:0031491 (0.01) ! nucleosome binding; GO:0031432 (0.01) ! titin binding; GO:0030507 (0.01) ! spectrin binding; GO:0030506 (0.01) ! ankyrin binding; GO:0030165 (0.01) ! PDZ domain binding; GO:0019902 (0.01) ! phosphatase binding; GO:0019901 (0.01) ! protein kinase binding; GO:0017049 (0.01) ! GTP-Rho binding; GO:0016887 (0.01) ! ATPase activity; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008093 (0.01) ! cytoskeletal adaptor activity; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005546 (0.01) ! phosphatidylinositol-4,5-bisphosphate binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005249 (0.01) ! voltage-gated potassium channel activity; GO:0005201 (0.01) ! extracellular matrix structural constituent; GO:0005102 (0.01) ! receptor binding; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0004872 (0.01) ! receptor activity; GO:0004871 (0.01) ! signal transducer activity; GO:0004857 (0.01) ! enzyme inhibitor activity; GO:0004674 (0.01) ! protein serine/threonine kinase activity; GO:0003777 (0.01) ! microtubule motor activity GO:0044699 (0.84) ! single-organism process; GO:0009987 (0.62) ! cellular process; GO:0044763 (0.55) ! single-organism cellular process; GO:0032501 (0.48) ! multicellular organismal process; GO:0044767 (0.46) ! single-organism developmental process; GO:0048856 (0.44) ! anatomical structure development; GO:0048869 (0.42) ! cellular developmental process; GO:0003008 (0.40) ! system process; GO:0051179 (0.37) ! localization; GO:0072015 (0.36) ! glomerular visceral epithelial cell development; GO:0006810 (0.36) ! transport; GO:0003094 (0.36) ! glomerular filtration; GO:0044765 (0.28) ! single-organism transport; GO:0071702 (0.26) ! organic substance transport; GO:0065007 (0.26) ! biological regulation; GO:0055085 (0.26) ! transmembrane transport; GO:0015931 (0.25) ! nucleobase-containing compound transport; GO:0072334 (0.24) ! UDP-galactose transmembrane transport; GO:0050794 (0.21) ! regulation of cellular process; GO:0065008 (0.17) ! regulation of biological quality; GO:0016043 (0.12) ! cellular component organization; GO:0042391 (0.11) ! regulation of membrane potential; GO:0051239 (0.10) ! regulation of multicellular organismal process; GO:0048522 (0.10) ! positive regulation of cellular process; GO:0008152 (0.10) ! metabolic process; GO:0044707 (0.09) ! single-multicellular organism process; GO:0007267 (0.08) ! cell-cell signaling; GO:0071704 (0.07) ! organic substance metabolic process; GO:0050896 (0.07) ! response to stimulus; GO:0044238 (0.07) ! primary metabolic process; GO:0044237 (0.07) ! cellular metabolic process; GO:0006996 (0.07) ! organelle organization; GO:1902589 (0.06) ! single-organism organelle organization; GO:1901360 (0.06) ! organic cyclic compound metabolic process; GO:0086010 (0.06) ! membrane depolarization during action potential; GO:0051128 (0.06) ! regulation of cellular component organization; GO:0048523 (0.06) ! negative regulation of cellular process; GO:0046483 (0.06) ! heterocycle metabolic process; GO:0044710 (0.06) ! single-organism metabolic process; GO:0009653 (0.06) ! anatomical structure morphogenesis; GO:0007010 (0.06) ! cytoskeleton organization; GO:0006816 (0.06) ! calcium ion transport; GO:1901576 (0.05) ! organic substance biosynthetic process; GO:0055114 (0.05) ! oxidation-reduction process; GO:0051641 (0.05) ! cellular localization; GO:0051130 (0.05) ! positive regulation of cellular component organization; GO:0050767 (0.05) ! regulation of neurogenesis; GO:0048646 (0.05) ! anatomical structure formation involved in morphogenesis; GO:0044249 (0.05) ! cellular biosynthetic process; GO:0042221 (0.05) ! response to chemical; GO:0032879 (0.05) ! regulation of localization; GO:0030036 (0.05) ! actin cytoskeleton organization; GO:0022603 (0.05) ! regulation of anatomical structure morphogenesis; GO:0008016 (0.05) ! regulation of heart contraction; GO:0007165 (0.05) ! signal transduction; GO:2000021 (0.04) ! regulation of ion homeostasis; GO:1901362 (0.04) ! organic cyclic compound biosynthetic process; GO:0070509 (0.04) ! calcium ion import; GO:0060255 (0.04) ! regulation of macromolecule metabolic process; GO:0051649 (0.04) ! establishment of localization in cell; GO:0051491 (0.04) ! positive regulation of filopodium assembly; GO:0051049 (0.04) ! regulation of transport; GO:0048813 (0.04) ! dendrite morphogenesis; GO:0045773 (0.04) ! positive regulation of axon extension; GO:0044281 (0.04) ! small molecule metabolic process; GO:0044260 (0.04) ! cellular macromolecule metabolic process; GO:0044255 (0.04) ! cellular lipid metabolic process; GO:0035149 (0.04) ! lumen formation, open tracheal system; GO:0035147 (0.04) ! branch fusion, open tracheal system; GO:0030716 (0.04) ! oocyte fate determination; GO:0018130 (0.04) ! heterocycle biosynthetic process; GO:0016319 (0.04) ! mushroom body development; GO:0016204 (0.04) ! determination of muscle attachment site; GO:0016203 (0.04) ! muscle attachment; GO:0016199 (0.04) ! axon midline choice point recognition; GO:0010646 (0.04) ! regulation of cell communication; GO:0010038 (0.04) ! response to metal ion; GO:0007475 (0.04) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.04) ! open tracheal system development; GO:0007423 (0.04) ! sensory organ development; GO:0007409 (0.04) ! axonogenesis; GO:0007268 (0.04) ! chemical synaptic transmission; GO:0007026 (0.04) ! negative regulation of microtubule depolymerization; GO:0002027 (0.04) ! regulation of heart rate; GO:0001578 (0.04) ! microtubule bundle formation; GO:0001508 (0.04) ! action potential; GO:2000112 (0.03) ! regulation of cellular macromolecule biosynthetic process; GO:0090304 (0.03) ! nucleic acid metabolic process; GO:0060371 (0.03) ! regulation of atrial cardiac muscle cell membrane depolarization; GO:0051252 (0.03) ! regulation of RNA metabolic process; GO:0051050 (0.03) ! positive regulation of transport; GO:0043933 (0.03) ! macromolecular complex subunit organization; GO:0042759 (0.03) ! long-chain fatty acid biosynthetic process; GO:0034613 (0.03) ! cellular protein localization; GO:0033068 (0.03) ! macrolide biosynthetic process; GO:0023051 (0.03) ! regulation of signaling; GO:0022607 (0.03) ! cellular component assembly; GO:0016192 (0.03) ! vesicle-mediated transport; GO:0010468 (0.03) ! regulation of gene expression; GO:0010045 (0.03) ! response to nickel cation; GO:0006457 (0.03) ! protein folding; GO:1902580 (0.02) ! single-organism cellular localization; GO:0061024 (0.02) ! membrane organization; GO:0051716 (0.02) ! cellular response to stimulus; GO:0048583 (0.02) ! regulation of response to stimulus; GO:0046903 (0.02) ! secretion; GO:0045956 (0.02) ! positive regulation of calcium ion-dependent exocytosis; GO:0045944 (0.02) ! positive regulation of transcription from RNA polymerase II promoter; GO:0044271 (0.02) ! cellular nitrogen compound biosynthetic process; GO:0044267 (0.02) ! cellular protein metabolic process; GO:0043412 (0.02) ! macromolecule modification; GO:0040011 (0.02) ! locomotion; GO:0035556 (0.02) ! intracellular signal transduction; GO:0034622 (0.02) ! cellular macromolecular complex assembly; GO:0034220 (0.02) ! ion transmembrane transport; GO:0030518 (0.02) ! intracellular steroid hormone receptor signaling pathway; GO:0022414 (0.02) ! reproductive process; GO:0016337 (0.02) ! single organismal cell-cell adhesion; GO:0016070 (0.02) ! RNA metabolic process; GO:0009059 (0.02) ! macromolecule biosynthetic process; GO:0007610 (0.02) ! behavior; GO:0007600 (0.02) ! sensory perception; GO:0007275 (0.02) ! multicellular organism development; GO:0006950 (0.02) ! response to stress; GO:0006928 (0.02) ! movement of cell or subcellular component; GO:0006886 (0.02) ! intracellular protein transport; GO:0006461 (0.02) ! protein complex assembly; GO:0006325 (0.02) ! chromatin organization; GO:0003013 (0.02) ! circulatory system process; GO:0002376 (0.02) ! immune system process; GO:1904062 (0.01) ! regulation of cation transmembrane transport; GO:1901700 (0.01) ! response to oxygen-containing compound; GO:1901361 (0.01) ! organic cyclic compound catabolic process; GO:0099643 (0.01) ! signal release from synapse; GO:0099531 (0.01) ! presynaptic process involved in chemical synaptic transmission; GO:0098910 (0.01) ! regulation of atrial cardiac muscle cell action potential; GO:0098779 (0.01) ! mitophagy in response to mitochondrial depolarization; GO:0090276 (0.01) ! regulation of peptide hormone secretion; GO:0090066 (0.01) ! regulation of anatomical structure size; GO:0086091 (0.01) ! regulation of heart rate by cardiac conduction; GO:0086070 (0.01) ! SA node cell to atrial cardiac muscle cell communication; GO:0086046 (0.01) ! membrane depolarization during SA node cell action potential; GO:0086015 (0.01) ! SA node cell action potential; GO:0072661 (0.01) ! protein targeting to plasma membrane; GO:0072659 (0.01) ! protein localization to plasma membrane; GO:0072507 (0.01) ! divalent inorganic cation homeostasis; GO:0070887 (0.01) ! cellular response to chemical stimulus; GO:0070588 (0.01) ! calcium ion transmembrane transport; GO:0060341 (0.01) ! regulation of cellular localization; GO:0060047 (0.01) ! heart contraction; GO:0060021 (0.01) ! palate development; GO:0055065 (0.01) ! metal ion homeostasis; GO:0051924 (0.01) ! regulation of calcium ion transport; GO:0051601 (0.01) ! exocyst localization; GO:0051315 (0.01) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051261 (0.01) ! protein depolymerization; GO:0051056 (0.01) ! regulation of small GTPase mediated signal transduction; GO:0050878 (0.01) ! regulation of body fluid levels; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0048729 (0.01) ! tissue morphogenesis; GO:0048598 (0.01) ! embryonic morphogenesis; GO:0048589 (0.01) ! developmental growth; GO:0048489 (0.01) ! synaptic vesicle transport; GO:0048488 (0.01) ! synaptic vesicle endocytosis; GO:0046486 (0.01) ! glycerolipid metabolic process; GO:0046164 (0.01) ! alcohol catabolic process; GO:0045892 (0.01) ! negative regulation of transcription, DNA-templated; GO:0045214 (0.01) ! sarcomere organization; GO:0045087 (0.01) ! innate immune response; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0044702 (0.01) ! single organism reproductive process; GO:0044248 (0.01) ! cellular catabolic process; GO:0044093 (0.01) ! positive regulation of molecular function; GO:0044092 (0.01) ! negative regulation of molecular function; GO:0043549 (0.01) ! regulation of kinase activity; GO:0043414 (0.01) ! macromolecule methylation; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0042330 (0.01) ! taxis; GO:0042110 (0.01) ! T cell activation; GO:0035372 (0.01) ! protein localization to microtubule; GO:0035107 (0.01) ! appendage morphogenesis; GO:0034660 (0.01) ! ncRNA metabolic process; GO:0034501 (0.01) ! protein localization to kinetochore; GO:0033993 (0.01) ! response to lipid; GO:0033554 (0.01) ! cellular response to stress; GO:0031134 (0.01) ! sister chromatid biorientation; GO:0030334 (0.01) ! regulation of cell migration; GO:0030241 (0.01) ! skeletal muscle myosin thick filament assembly; GO:0030239 (0.01) ! myofibril assembly; GO:0030155 (0.01) ! regulation of cell adhesion; GO:0022008 (0.01) ! neurogenesis; GO:0019827 (0.01) ! stem cell population maintenance; GO:0019725 (0.01) ! cellular homeostasis; GO:0019233 (0.01) ! sensory perception of pain; GO:0016477 (0.01) ! cell migration; GO:0016071 (0.01) ! mRNA metabolic process; GO:0016055 (0.01) ! Wnt signaling pathway; GO:0016050 (0.01) ! vesicle organization; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0010638 (0.01) ! positive regulation of organelle organization; GO:0009967 (0.01) ! positive regulation of signal transduction; GO:0009887 (0.01) ! organ morphogenesis; GO:0009628 (0.01) ! response to abiotic stimulus; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0007626 (0.01) ! locomotory behavior; GO:0007612 (0.01) ! learning; GO:0007605 (0.01) ! sensory perception of sound; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007416 (0.01) ! synapse assembly; GO:0007346 (0.01) ! regulation of mitotic cell cycle; GO:0007018 (0.01) ! microtubule-based movement; GO:0006913 (0.01) ! nucleocytoplasmic transport; GO:0006893 (0.01) ! Golgi to plasma membrane transport; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006887 (0.01) ! exocytosis; GO:0006836 (0.01) ! neurotransmitter transport; GO:0006796 (0.01) ! phosphate-containing compound metabolic process; GO:0006464 (0.01) ! cellular protein modification process; GO:0006396 (0.01) ! RNA processing; GO:0006366 (0.01) ! transcription from RNA polymerase II promoter; GO:0006338 (0.01) ! chromatin remodeling; GO:0006336 (0.01) ! DNA replication-independent nucleosome assembly; GO:0006259 (0.01) ! DNA metabolic process; GO:0003012 (0.01) ! muscle system process; GO:0003006 (0.01) ! developmental process involved in reproduction; GO:0001932 (0.01) ! regulation of protein phosphorylation; GO:0001701 (0.01) ! in utero embryonic development GO:0044464 (1.00) ! cell part; GO:0044424 (0.96) ! intracellular part; GO:0044444 (0.62) ! cytoplasmic part; GO:0005737 (0.57) ! cytoplasm; GO:0044422 (0.38) ! organelle part; GO:0044446 (0.36) ! intracellular organelle part; GO:0043229 (0.35) ! intracellular organelle; GO:0032991 (0.29) ! macromolecular complex; GO:0043234 (0.28) ! protein complex; GO:0044425 (0.25) ! membrane part; GO:0043227 (0.25) ! membrane-bounded organelle; GO:0043231 (0.24) ! intracellular membrane-bounded organelle; GO:0016021 (0.22) ! integral component of membrane; GO:0044431 (0.21) ! Golgi apparatus part; GO:0030176 (0.21) ! integral component of endoplasmic reticulum membrane; GO:0030173 (0.20) ! integral component of Golgi membrane; GO:0016020 (0.17) ! membrane; GO:0005886 (0.15) ! plasma membrane; GO:0005829 (0.13) ! cytosol; GO:0044445 (0.12) ! cytosolic part; GO:0043232 (0.11) ! intracellular non-membrane-bounded organelle; GO:0044428 (0.09) ! nuclear part; GO:0044421 (0.08) ! extracellular region part; GO:1903561 (0.07) ! extracellular vesicle; GO:0044451 (0.07) ! nucleoplasm part; GO:0031988 (0.07) ! membrane-bounded vesicle; GO:0097458 (0.06) ! neuron part; GO:0070062 (0.06) ! extracellular exosome; GO:0044430 (0.06) ! cytoskeletal part; GO:0030312 (0.06) ! external encapsulating structure; GO:0044463 (0.05) ! cell projection part; GO:0042995 (0.05) ! cell projection; GO:0042597 (0.05) ! periplasmic space; GO:0034081 (0.05) ! polyketide synthase complex; GO:0005835 (0.05) ! fatty acid synthase complex; GO:0005832 (0.05) ! chaperonin-containing T-complex; GO:0005811 (0.05) ! lipid particle; GO:0005777 (0.05) ! peroxisome; GO:0005768 (0.05) ! endosome; GO:0005739 (0.05) ! mitochondrion; GO:0005634 (0.05) ! nucleus; GO:0005618 (0.05) ! cell wall; GO:0044459 (0.04) ! plasma membrane part; GO:0033267 (0.04) ! axon part; GO:0030054 (0.04) ! cell junction; GO:0005874 (0.04) ! microtubule; GO:0005856 (0.04) ! cytoskeleton; GO:0005665 (0.04) ! DNA-directed RNA polymerase II, core complex; GO:0098796 (0.03) ! membrane protein complex; GO:0045169 (0.03) ! fusome; GO:0044295 (0.03) ! axonal growth cone; GO:0035371 (0.03) ! microtubule plus-end; GO:0030175 (0.03) ! filopodium; GO:0005927 (0.03) ! muscle tendon junction; GO:0000235 (0.03) ! astral microtubule; GO:0098797 (0.02) ! plasma membrane protein complex; GO:0098590 (0.02) ! plasma membrane region; GO:0070847 (0.02) ! core mediator complex; GO:0044456 (0.02) ! synapse part; GO:0044449 (0.02) ! contractile fiber part; GO:0043005 (0.02) ! neuron projection; GO:0016592 (0.02) ! mediator complex; GO:0005654 (0.02) ! nucleoplasm; GO:0097060 (0.01) ! synaptic membrane; GO:0072686 (0.01) ! mitotic spindle; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0045202 (0.01) ! synapse; GO:0043195 (0.01) ! terminal bouton; GO:0043034 (0.01) ! costamere; GO:0043025 (0.01) ! neuronal cell body; GO:0032044 (0.01) ! DSIF complex; GO:0031430 (0.01) ! M band; GO:0031012 (0.01) ! extracellular matrix; GO:0030496 (0.01) ! midbody; GO:0030425 (0.01) ! dendrite; GO:0030134 (0.01) ! ER to Golgi transport vesicle; GO:0030132 (0.01) ! clathrin coat of coated pit; GO:0030018 (0.01) ! Z disc; GO:0012506 (0.01) ! vesicle membrane; GO:0009986 (0.01) ! cell surface; GO:0005911 (0.01) ! cell-cell junction; GO:0005891 (0.01) ! voltage-gated calcium channel complex; GO:0005887 (0.01) ! integral component of plasma membrane; GO:0005875 (0.01) ! microtubule associated complex; GO:0005802 (0.01) ! trans-Golgi network; GO:0005643 (0.01) ! nuclear pore; GO:0005615 (0.01) ! extracellular space; GO:0000776 (0.01) ! kinetochore; GO:0000145 (0.01) ! exocyst 2 49710332-49789180 (17q21.33) High: stomach 2 (glandular cells);stomach 1 (glandular cells);seminal vesicle (glandular cells);colon (endothelial cells; glandular cells; peripheral nerve/ganglion);gallbladder (glandular cells);kidney (cells in tubules);testis (Leydig cells);thyroid gland (glandular cells);epididymis (glandular cells);adrenal gland (glandular cells);endometrium 1 (glandular cells);endometrium 2 (glandular cells);salivary gland (glandular cells);duodenum (glandular cells);placenta (decidual cells; trophoblastic cells);parathyroid gland (glandular cells);urinary bladder (urothelial cells);appendix (glandular cells);breast (glandular cells; myoepithelial cells);rectum (glandular cells);prostate (glandular cells);cervix, uterine (squamous epithelial cells);pancreas (exocrine glandular cells);cerebellum (Purkinje cells);fallopian tube (glandular cells);bone marrow (hematopoietic cells);soft tissue 2 (fibroblasts);small intestine (glandular cells);soft tissue 1 (fibroblasts);lung (pneumocytes);skin 1 (fibroblasts);Medium: lung (macrophages);esophagus (squamous epithelial cells);kidney (cells in glomeruli);testis (cells in seminiferous ducts);caudate (glial cells; neuronal cells);tonsil (germinal center cells; non-germinal center cells; squamous epithelial cells);breast (adipocytes);vagina (squamous epithelial cells);endometrium 1 (cells in endometrial stroma);endometrium 2 (cells in endometrial stroma);smooth muscle (smooth muscle cells);heart muscle (myocytes);cerebral cortex (endothelial cells; glial cells; neuronal cells);lymph node (non-germinal center cells);hippocampus (glial cells; neuronal cells);bronchus (respiratory epithelial cells);skeletal muscle (myocytes);appendix (lymphoid tissue);liver (bile duct cells; hepatocytes);cervix, uterine (glandular cells);pancreas (islets of Langerhans);cerebellum (cells in granular layer; cells in molecular layer);soft tissue 1 (adipocytes; chondrocytes; peripheral nerve);soft tissue 2 (peripheral nerve);ovary (follicle cells; ovarian stroma cells);oral mucosa (squamous epithelial cells);skin 1 (keratinocytes; Langerhans; melanocytes);skin 2 (epidermal cells);Low: lymph node (germinal center cells);cerebral cortex (neuropil); Spleen: 45.19; Cells - EBV-transformed lymphocytes: 41.30; Uterus: 35.30; Whole Blood: 34.07; Testis: 33.86; Artery - Tibial: 32.15; Colon - Sigmoid: 30.59; Ovary: 30.38; Bladder: 29.34; Fallopian Tube: 27.13; Skin - Sun Exposed (Lower leg): 23.26; Artery - Coronary: 23.02; Esophagus - Gastroesophageal Junction: 22.82; Thyroid: 22.63; Skin - Not Sun Exposed (Suprapubic): 22.63; Artery - Aorta: 21.55; Pituitary: 21.19; Esophagus - Muscularis: 20.98; Small Intestine - Terminal Ileum: 20.40; Cervix - Endocervix: 18.95; Nerve - Tibial: 18.16; Adipose - Subcutaneous: 16.77; Brain - Cerebellum: 16.15; Breast - Mammary Tissue: 16.10; Vagina: 15.19; Cervix - Ectocervix: 15.01; Brain - Cerebellar Hemisphere: 14.06; Prostate: 14.03; Lung: 13.81; Colon - Transverse: 12.93; Minor Salivary Gland: 12.73; Adipose - Visceral (Omentum): 12.46; Stomach: 10.55; Esophagus - Mucosa: 9.50; Pancreas: 7.96; Heart - Atrial Appendage: 7.74; Kidney - Cortex: 7.69; Adrenal Gland: 7.50; Brain - Nucleus accumbens (basal ganglia): 6.59; Liver: 5.75; Heart - Left Ventricle: 5.11; Brain - Caudate (basal ganglia): 4.78; Cells - Transformed fibroblasts: 4.31; Brain - Hypothalamus: 3.70; Brain - Putamen (basal ganglia): 3.61; Brain - Cortex: 3.48; Brain - Amygdala: 3.44; Brain - Frontal Cortex (BA9): 3.38; Brain - Anterior cingulate cortex (BA24): 3.32; Brain - Hippocampus: 2.92; Brain - Spinal cord (cervical c-1): 2.36; Brain - Substantia nigra: 2.33; Muscle - Skeletal: 2.04; MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPFQLQQPHQRRDGGGRAASVPCSVAPEKSVCRPQPLQVRRTFSLDTILSSYLLGQWPRDADGAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISKLKQQLQRTKLSRSGKEKERGSPLLGDHAVRGALRASPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGPDLAFLTSCPDKNKVHFNPTGSAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEEPVLFQSSLMV SAMD14 Sterile alpha motif domain-containing protein 14 SAM14_HUMAN (Q8IZD0-1) GO:0003824 (0.55) ! catalytic activity; GO:0044877 (0.48) ! macromolecular complex binding; GO:0032403 (0.47) ! protein complex binding; GO:0051015 (0.45) ! actin filament binding; GO:1901363 (0.43) ! heterocyclic compound binding; GO:0097159 (0.43) ! organic cyclic compound binding; GO:0043169 (0.42) ! cation binding; GO:0097367 (0.41) ! carbohydrate derivative binding; GO:0017076 (0.41) ! purine nucleotide binding; GO:0035639 (0.40) ! purine ribonucleoside triphosphate binding; GO:0032559 (0.40) ! adenyl ribonucleotide binding; GO:0032550 (0.40) ! purine ribonucleoside binding; GO:0016879 (0.40) ! ligase activity, forming carbon-nitrogen bonds; GO:0016421 (0.25) ! CoA carboxylase activity; GO:0016740 (0.13) ! transferase activity; GO:0016787 (0.12) ! hydrolase activity; GO:0016773 (0.12) ! phosphotransferase activity, alcohol group as acceptor; GO:0016301 (0.12) ! kinase activity; GO:0016788 (0.11) ! hydrolase activity, acting on ester bonds; GO:0042802 (0.09) ! identical protein binding; GO:0004672 (0.09) ! protein kinase activity; GO:0004871 (0.08) ! signal transducer activity; GO:0004620 (0.07) ! phospholipase activity; GO:0019904 (0.06) ! protein domain specific binding; GO:0042803 (0.05) ! protein homodimerization activity; GO:0005102 (0.05) ! receptor binding; GO:0004713 (0.05) ! protein tyrosine kinase activity; GO:0008022 (0.04) ! protein C-terminus binding; GO:0005003 (0.04) ! ephrin receptor activity; GO:0003676 (0.04) ! nucleic acid binding; GO:0046872 (0.03) ! metal ion binding; GO:0042578 (0.03) ! phosphoric ester hydrolase activity; GO:0035255 (0.03) ! ionotropic glutamate receptor binding; GO:0019899 (0.03) ! enzyme binding; GO:0005198 (0.03) ! structural molecule activity; GO:0004702 (0.03) ! receptor signaling protein serine/threonine kinase activity; GO:0004143 (0.03) ! diacylglycerol kinase activity; GO:0003677 (0.03) ! DNA binding; GO:0098772 (0.02) ! molecular function regulator; GO:0097110 (0.02) ! scaffold protein binding; GO:0051020 (0.02) ! GTPase binding; GO:0046982 (0.02) ! protein heterodimerization activity; GO:0035312 (0.02) ! 5'-3' exodeoxyribonuclease activity; GO:0030160 (0.02) ! GKAP/Homer scaffold activity; GO:0019903 (0.02) ! protein phosphatase binding; GO:0019901 (0.02) ! protein kinase binding; GO:0017124 (0.02) ! SH3 domain binding; GO:0008832 (0.02) ! dGTPase activity; GO:0008270 (0.02) ! zinc ion binding; GO:0005005 (0.02) ! transmembrane-ephrin receptor activity; GO:0005004 (0.02) ! GPI-linked ephrin receptor activity; GO:0003723 (0.02) ! RNA binding; GO:0003684 (0.02) ! damaged DNA binding; GO:0003682 (0.02) ! chromatin binding; GO:0097161 (0.01) ! DH domain binding; GO:0071532 (0.01) ! ankyrin repeat binding; GO:0070064 (0.01) ! proline-rich region binding; GO:0052745 (0.01) ! inositol phosphate phosphatase activity; GO:0046935 (0.01) ! 1-phosphatidylinositol-3-kinase regulator activity; GO:0046875 (0.01) ! ephrin receptor binding; GO:0044822 (0.01) ! poly(A) RNA binding; GO:0044325 (0.01) ! ion channel binding; GO:0042169 (0.01) ! SH2 domain binding; GO:0035591 (0.01) ! signaling adaptor activity; GO:0035064 (0.01) ! methylated histone binding; GO:0032567 (0.01) ! dGTP binding; GO:0032093 (0.01) ! SAM domain binding; GO:0031877 (0.01) ! somatostatin receptor binding; GO:0008157 (0.01) ! protein phosphatase 1 binding; GO:0008046 (0.01) ! axon guidance receptor activity; GO:0005547 (0.01) ! phosphatidylinositol-3,4,5-trisphosphate binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005246 (0.01) ! calcium channel regulator activity; GO:0004806 (0.01) ! triglyceride lipase activity; GO:0004709 (0.01) ! MAP kinase kinase kinase activity; GO:0003700 (0.01) ! transcription factor activity, sequence-specific DNA binding GO:0044699 (0.84) ! single-organism process; GO:0009987 (0.83) ! cellular process; GO:0065007 (0.80) ! biological regulation; GO:0050789 (0.78) ! regulation of biological process; GO:0044763 (0.75) ! single-organism cellular process; GO:0050794 (0.73) ! regulation of cellular process; GO:0016043 (0.64) ! cellular component organization; GO:0007165 (0.61) ! signal transduction; GO:0030030 (0.49) ! cell projection organization; GO:0035556 (0.47) ! intracellular signal transduction; GO:0019932 (0.46) ! second-messenger-mediated signaling; GO:0031175 (0.45) ! neuron projection development; GO:0019722 (0.45) ! calcium-mediated signaling; GO:0007015 (0.44) ! actin filament organization; GO:0071704 (0.37) ! organic substance metabolic process; GO:0044238 (0.37) ! primary metabolic process; GO:0044237 (0.37) ! cellular metabolic process; GO:0044710 (0.30) ! single-organism metabolic process; GO:0044281 (0.27) ! small molecule metabolic process; GO:0044255 (0.27) ! cellular lipid metabolic process; GO:0072330 (0.25) ! monocarboxylic acid biosynthetic process; GO:0008610 (0.25) ! lipid biosynthetic process; GO:0006631 (0.25) ! fatty acid metabolic process; GO:0032502 (0.14) ! developmental process; GO:0048518 (0.13) ! positive regulation of biological process; GO:0044767 (0.13) ! single-organism developmental process; GO:0050896 (0.12) ! response to stimulus; GO:0048523 (0.12) ! negative regulation of cellular process; GO:0007610 (0.12) ! behavior; GO:0051704 (0.11) ! multi-organism process; GO:0044260 (0.11) ! cellular macromolecule metabolic process; GO:0023051 (0.11) ! regulation of signaling; GO:0010646 (0.11) ! regulation of cell communication; GO:0051128 (0.10) ! regulation of cellular component organization; GO:0048583 (0.10) ! regulation of response to stimulus; GO:0044708 (0.10) ! single-organism behavior; GO:0043412 (0.10) ! macromolecule modification; GO:0019222 (0.10) ! regulation of metabolic process; GO:0006796 (0.10) ! phosphate-containing compound metabolic process; GO:0080090 (0.09) ! regulation of primary metabolic process; GO:0065008 (0.09) ! regulation of biological quality; GO:0060255 (0.09) ! regulation of macromolecule metabolic process; GO:0051705 (0.09) ! multi-organism behavior; GO:0051179 (0.09) ! localization; GO:0048522 (0.09) ! positive regulation of cellular process; GO:0031323 (0.09) ! regulation of cellular metabolic process; GO:0065009 (0.08) ! regulation of molecular function; GO:0050793 (0.08) ! regulation of developmental process; GO:0048856 (0.08) ! anatomical structure development; GO:0044087 (0.08) ! regulation of cellular component biogenesis; GO:0022607 (0.08) ! cellular component assembly; GO:0009966 (0.08) ! regulation of signal transduction; GO:0006996 (0.08) ! organelle organization; GO:0051960 (0.07) ! regulation of nervous system development; GO:0048869 (0.07) ! cellular developmental process; GO:0042048 (0.07) ! olfactory behavior; GO:0032501 (0.07) ! multicellular organismal process; GO:0016310 (0.07) ! phosphorylation; GO:0009653 (0.07) ! anatomical structure morphogenesis; GO:0007166 (0.07) ! cell surface receptor signaling pathway; GO:0006464 (0.07) ! cellular protein modification process; GO:0051129 (0.06) ! negative regulation of cellular component organization; GO:0050808 (0.06) ! synapse organization; GO:0050790 (0.06) ! regulation of catalytic activity; GO:0044707 (0.06) ! single-multicellular organism process; GO:0043933 (0.06) ! macromolecular complex subunit organization; GO:0042221 (0.06) ! response to chemical; GO:0032879 (0.06) ! regulation of localization; GO:0023057 (0.06) ! negative regulation of signaling; GO:0010648 (0.06) ! negative regulation of cell communication; GO:0007169 (0.06) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0006950 (0.06) ! response to stress; GO:0006810 (0.06) ! transport; GO:0006468 (0.06) ! protein phosphorylation; GO:0006139 (0.06) ! nucleobase-containing compound metabolic process; GO:0002121 (0.06) ! inter-male aggressive behavior; GO:0001932 (0.06) ! regulation of protein phosphorylation; GO:1902531 (0.05) ! regulation of intracellular signal transduction; GO:0051716 (0.05) ! cellular response to stimulus; GO:0051240 (0.05) ! positive regulation of multicellular organismal process; GO:0051130 (0.05) ! positive regulation of cellular component organization; GO:0051094 (0.05) ! positive regulation of developmental process; GO:0051049 (0.05) ! regulation of transport; GO:0050807 (0.05) ! regulation of synapse organization; GO:0050804 (0.05) ! modulation of synaptic transmission; GO:0045595 (0.05) ! regulation of cell differentiation; GO:0044093 (0.05) ! positive regulation of molecular function; GO:0032956 (0.05) ! regulation of actin cytoskeleton organization; GO:0023056 (0.05) ! positive regulation of signaling; GO:0022414 (0.05) ! reproductive process; GO:0010647 (0.05) ! positive regulation of cell communication; GO:0080134 (0.04) ! regulation of response to stress; GO:0051963 (0.04) ! regulation of synapse assembly; GO:0051962 (0.04) ! positive regulation of nervous system development; GO:0051649 (0.04) ! establishment of localization in cell; GO:0051641 (0.04) ! cellular localization; GO:0051338 (0.04) ! regulation of transferase activity; GO:0050877 (0.04) ! neurological system process; GO:0048812 (0.04) ! neuron projection morphogenesis; GO:0048513 (0.04) ! animal organ development; GO:0048167 (0.04) ! regulation of synaptic plasticity; GO:0048013 (0.04) ! ephrin receptor signaling pathway; GO:0044702 (0.04) ! single organism reproductive process; GO:0043408 (0.04) ! regulation of MAPK cascade; GO:0040011 (0.04) ! locomotion; GO:0032232 (0.04) ! negative regulation of actin filament bundle assembly; GO:0031325 (0.04) ! positive regulation of cellular metabolic process; GO:0022604 (0.04) ! regulation of cell morphogenesis; GO:0022402 (0.04) ! cell cycle process; GO:0019637 (0.04) ! organophosphate metabolic process; GO:0016192 (0.04) ! vesicle-mediated transport; GO:0010975 (0.04) ! regulation of neuron projection development; GO:0010605 (0.04) ! negative regulation of macromolecule metabolic process; GO:0010604 (0.04) ! positive regulation of macromolecule metabolic process; GO:0009889 (0.04) ! regulation of biosynthetic process; GO:0009605 (0.04) ! response to external stimulus; GO:0007416 (0.04) ! synapse assembly; GO:0006928 (0.04) ! movement of cell or subcellular component; GO:0006461 (0.04) ! protein complex assembly; GO:0006259 (0.04) ! DNA metabolic process; GO:1903046 (0.03) ! meiotic cell cycle process; GO:1902578 (0.03) ! single-organism localization; GO:0071625 (0.03) ! vocalization behavior; GO:0070887 (0.03) ! cellular response to chemical stimulus; GO:0070372 (0.03) ! regulation of ERK1 and ERK2 cascade; GO:0060999 (0.03) ! positive regulation of dendritic spine development; GO:0060997 (0.03) ! dendritic spine morphogenesis; GO:0060341 (0.03) ! regulation of cellular localization; GO:0051492 (0.03) ! regulation of stress fiber assembly; GO:0051259 (0.03) ! protein oligomerization; GO:0050806 (0.03) ! positive regulation of synaptic transmission; GO:0050805 (0.03) ! negative regulation of synaptic transmission; GO:0048814 (0.03) ! regulation of dendrite morphogenesis; GO:0046777 (0.03) ! protein autophosphorylation; GO:0046486 (0.03) ! glycerolipid metabolic process; GO:0045859 (0.03) ! regulation of protein kinase activity; GO:0043269 (0.03) ! regulation of ion transport; GO:0042592 (0.03) ! homeostatic process; GO:0042391 (0.03) ! regulation of membrane potential; GO:0035176 (0.03) ! social behavior; GO:0034660 (0.03) ! ncRNA metabolic process; GO:0033554 (0.03) ! cellular response to stress; GO:0031324 (0.03) ! negative regulation of cellular metabolic process; GO:0018193 (0.03) ! peptidyl-amino acid modification; GO:0016477 (0.03) ! cell migration; GO:0010033 (0.03) ! response to organic substance; GO:0009968 (0.03) ! negative regulation of signal transduction; GO:0009967 (0.03) ! positive regulation of signal transduction; GO:0009887 (0.03) ! organ morphogenesis; GO:0008104 (0.03) ! protein localization; GO:0007612 (0.03) ! learning; GO:0007411 (0.03) ! axon guidance; GO:0007283 (0.03) ! spermatogenesis; GO:0007155 (0.03) ! cell adhesion; GO:0006888 (0.03) ! ER to Golgi vesicle-mediated transport; GO:0006355 (0.03) ! regulation of transcription, DNA-templated; GO:0002682 (0.03) ! regulation of immune system process; GO:0001934 (0.03) ! positive regulation of protein phosphorylation; GO:0000280 (0.03) ! nuclear division; GO:1903530 (0.02) ! regulation of secretion by cell; GO:1900452 (0.02) ! regulation of long term synaptic depression; GO:1900271 (0.02) ! regulation of long-term synaptic potentiation; GO:0080135 (0.02) ! regulation of cellular response to stress; GO:0061001 (0.02) ! regulation of dendritic spine morphogenesis; GO:0060996 (0.02) ! dendritic spine development; GO:0060292 (0.02) ! long term synaptic depression; GO:0060291 (0.02) ! long-term synaptic potentiation; GO:0051965 (0.02) ! positive regulation of synapse assembly; GO:0051961 (0.02) ! negative regulation of nervous system development; GO:0051823 (0.02) ! regulation of synapse structural plasticity; GO:0051607 (0.02) ! defense response to virus; GO:0051497 (0.02) ! negative regulation of stress fiber assembly; GO:0051276 (0.02) ! chromosome organization; GO:0051260 (0.02) ! protein homooligomerization; GO:0050795 (0.02) ! regulation of behavior; GO:0048854 (0.02) ! brain morphogenesis; GO:0048646 (0.02) ! anatomical structure formation involved in morphogenesis; GO:0048638 (0.02) ! regulation of developmental growth; GO:0048468 (0.02) ! cell development; GO:0048168 (0.02) ! regulation of neuronal synaptic plasticity; GO:0046339 (0.02) ! diacylglycerol metabolic process; GO:0045926 (0.02) ! negative regulation of growth; GO:0045892 (0.02) ! negative regulation of transcription, DNA-templated; GO:0045860 (0.02) ! positive regulation of protein kinase activity; GO:0045088 (0.02) ! regulation of innate immune response; GO:0043410 (0.02) ! positive regulation of MAPK cascade; GO:0043087 (0.02) ! regulation of GTPase activity; GO:0043046 (0.02) ! DNA methylation involved in gamete generation; GO:0040012 (0.02) ! regulation of locomotion; GO:0036269 (0.02) ! swimming behavior; GO:0035640 (0.02) ! exploration behavior; GO:0034587 (0.02) ! piRNA metabolic process; GO:0032535 (0.02) ! regulation of cellular component size; GO:0032414 (0.02) ! positive regulation of ion transmembrane transporter activity; GO:0031589 (0.02) ! cell-substrate adhesion; GO:0031400 (0.02) ! negative regulation of protein modification process; GO:0030534 (0.02) ! adult behavior; GO:0030155 (0.02) ! regulation of cell adhesion; GO:0030154 (0.02) ! cell differentiation; GO:0021700 (0.02) ! developmental maturation; GO:0019725 (0.02) ! cellular homeostasis; GO:0018108 (0.02) ! peptidyl-tyrosine phosphorylation; GO:0010941 (0.02) ! regulation of cell death; GO:0007613 (0.02) ! memory; GO:0007205 (0.02) ! protein kinase C-activating G-protein coupled receptor signaling pathway; GO:0007154 (0.02) ! cell communication; GO:0007140 (0.02) ! male meiosis; GO:0007030 (0.02) ! Golgi organization; GO:0006974 (0.02) ! cellular response to DNA damage stimulus; GO:0006811 (0.02) ! ion transport; GO:0006644 (0.02) ! phospholipid metabolic process; GO:0006203 (0.02) ! dGTP catabolic process; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0001505 (0.02) ! regulation of neurotransmitter levels; GO:2001108 (0.01) ! positive regulation of Rho guanyl-nucleotide exchange factor activity; GO:2000969 (0.01) ! positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; GO:2000822 (0.01) ! regulation of behavioral fear response; GO:2000821 (0.01) ! regulation of grooming behavior; GO:2000463 (0.01) ! positive regulation of excitatory postsynaptic potential; GO:1904049 (0.01) ! negative regulation of spontaneous neurotransmitter secretion; GO:1903047 (0.01) ! mitotic cell cycle process; GO:1902589 (0.01) ! single-organism organelle organization; GO:1901700 (0.01) ! response to oxygen-containing compound; GO:1900454 (0.01) ! positive regulation of long term synaptic depression; GO:1900376 (0.01) ! regulation of secondary metabolite biosynthetic process; GO:1900273 (0.01) ! positive regulation of long-term synaptic potentiation; GO:1900272 (0.01) ! negative regulation of long-term synaptic potentiation; GO:0097237 (0.01) ! cellular response to toxic substance; GO:0097120 (0.01) ! receptor localization to synapse; GO:0097117 (0.01) ! guanylate kinase-associated protein clustering; GO:0097114 (0.01) ! NMDA glutamate receptor clustering; GO:0097113 (0.01) ! AMPA glutamate receptor clustering; GO:0097107 (0.01) ! postsynaptic density assembly; GO:0090090 (0.01) ! negative regulation of canonical Wnt signaling pathway; GO:0090005 (0.01) ! negative regulation of establishment of protein localization to plasma membrane; GO:0071364 (0.01) ! cellular response to epidermal growth factor stimulus; GO:0071214 (0.01) ! cellular response to abiotic stimulus; GO:0070791 (0.01) ! cleistothecium development; GO:0070374 (0.01) ! positive regulation of ERK1 and ERK2 cascade; GO:0070373 (0.01) ! negative regulation of ERK1 and ERK2 cascade; GO:0061351 (0.01) ! neural precursor cell proliferation; GO:0060326 (0.01) ! cell chemotaxis; GO:0060079 (0.01) ! excitatory postsynaptic potential; GO:0060074 (0.01) ! synapse maturation; GO:0051968 (0.01) ! positive regulation of synaptic transmission, glutamatergic; GO:0051835 (0.01) ! positive regulation of synapse structural plasticity; GO:0051496 (0.01) ! positive regulation of stress fiber assembly; GO:0051489 (0.01) ! regulation of filopodium assembly; GO:0051053 (0.01) ! negative regulation of DNA metabolic process; GO:0050965 (0.01) ! detection of temperature stimulus involved in sensory perception of pain; GO:0050885 (0.01) ! neuromuscular process controlling balance; GO:0050770 (0.01) ! regulation of axonogenesis; GO:0048731 (0.01) ! system development; GO:0048666 (0.01) ! neuron development; GO:0048589 (0.01) ! developmental growth; GO:0048534 (0.01) ! hematopoietic or lymphoid organ development; GO:0048172 (0.01) ! regulation of short-term neuronal synaptic plasticity; GO:0048170 (0.01) ! positive regulation of long-term neuronal synaptic plasticity; GO:0046854 (0.01) ! phosphatidylinositol phosphorylation; GO:0046328 (0.01) ! regulation of JNK cascade; GO:0046061 (0.01) ! dATP catabolic process; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045930 (0.01) ! negative regulation of mitotic cell cycle; GO:0045886 (0.01) ! negative regulation of synaptic growth at neuromuscular junction; GO:0045794 (0.01) ! negative regulation of cell volume; GO:0045087 (0.01) ! innate immune response; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0043647 (0.01) ! inositol phosphate metabolic process; GO:0043551 (0.01) ! regulation of phosphatidylinositol 3-kinase activity; GO:0043523 (0.01) ! regulation of neuron apoptotic process; GO:0043407 (0.01) ! negative regulation of MAP kinase activity; GO:0043051 (0.01) ! regulation of pharyngeal pumping; GO:0042297 (0.01) ! vocal learning; GO:0040029 (0.01) ! regulation of gene expression, epigenetic; GO:0040017 (0.01) ! positive regulation of locomotion; GO:0036297 (0.01) ! interstrand cross-link repair; GO:0035641 (0.01) ! locomotory exploration behavior; GO:0034599 (0.01) ! cellular response to oxidative stress; GO:0034446 (0.01) ! substrate adhesion-dependent cell spreading; GO:0033993 (0.01) ! response to lipid; GO:0033137 (0.01) ! negative regulation of peptidyl-serine phosphorylation; GO:0032237 (0.01) ! activation of store-operated calcium channel activity; GO:0032147 (0.01) ! activation of protein kinase activity; GO:0032102 (0.01) ! negative regulation of response to external stimulus; GO:0031848 (0.01) ! protection from non-homologous end joining at telomere; GO:0031290 (0.01) ! retinal ganglion cell axon guidance; GO:0030833 (0.01) ! regulation of actin filament polymerization; GO:0030336 (0.01) ! negative regulation of cell migration; GO:0030168 (0.01) ! platelet activation; GO:0030162 (0.01) ! regulation of proteolysis; GO:0030010 (0.01) ! establishment of cell polarity; GO:0022412 (0.01) ! cellular process involved in reproduction in multicellular organism; GO:0022407 (0.01) ! regulation of cell-cell adhesion; GO:0022008 (0.01) ! neurogenesis; GO:0021952 (0.01) ! central nervous system projection neuron axonogenesis; GO:0021773 (0.01) ! striatal medium spiny neuron differentiation; GO:0017157 (0.01) ! regulation of exocytosis; GO:0016925 (0.01) ! protein sumoylation; GO:0016574 (0.01) ! histone ubiquitination; GO:0016458 (0.01) ! gene silencing; GO:0016322 (0.01) ! neuron remodeling; GO:0016049 (0.01) ! cell growth; GO:0014047 (0.01) ! glutamate secretion; GO:0010977 (0.01) ! negative regulation of neuron projection development; GO:0010948 (0.01) ! negative regulation of cell cycle process; GO:0010765 (0.01) ! positive regulation of sodium ion transport; GO:0009725 (0.01) ! response to hormone; GO:0009267 (0.01) ! cellular response to starvation; GO:0008360 (0.01) ! regulation of cell shape; GO:0008306 (0.01) ! associative learning; GO:0008286 (0.01) ! insulin receptor signaling pathway; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0007616 (0.01) ! long-term memory; GO:0007608 (0.01) ! sensory perception of smell; GO:0007568 (0.01) ! aging; GO:0007528 (0.01) ! neuromuscular junction development; GO:0007507 (0.01) ! heart development; GO:0007420 (0.01) ! brain development; GO:0007413 (0.01) ! axonal fasciculation; GO:0007412 (0.01) ! axon target recognition; GO:0007368 (0.01) ! determination of left/right symmetry; GO:0007269 (0.01) ! neurotransmitter secretion; GO:0007173 (0.01) ! epidermal growth factor receptor signaling pathway; GO:0007088 (0.01) ! regulation of mitotic nuclear division; GO:0007017 (0.01) ! microtubule-based process; GO:0007010 (0.01) ! cytoskeleton organization; GO:0006929 (0.01) ! substrate-dependent cell migration; GO:0006897 (0.01) ! endocytosis; GO:0006874 (0.01) ! cellular calcium ion homeostasis; GO:0006661 (0.01) ! phosphatidylinositol biosynthetic process; GO:0006303 (0.01) ! double-strand break repair via nonhomologous end joining; GO:0002115 (0.01) ! store-operated calcium entry; GO:0002009 (0.01) ! morphogenesis of an epithelium; GO:0001958 (0.01) ! endochondral ossification; GO:0001525 (0.01) ! angiogenesis; GO:0000750 (0.01) ! pheromone-dependent signal transduction involved in conjugation with cellular fusion; GO:0000165 (0.01) ! MAPK cascade; GO:0000003 (0.01) ! reproduction GO:0044424 (1.00) ! intracellular part; GO:0043226 (0.84) ! organelle; GO:0043229 (0.83) ! intracellular organelle; GO:0044444 (0.81) ! cytoplasmic part; GO:0005737 (0.81) ! cytoplasm; GO:0044446 (0.64) ! intracellular organelle part; GO:0043232 (0.61) ! intracellular non-membrane-bounded organelle; GO:0043231 (0.61) ! intracellular membrane-bounded organelle; GO:0097458 (0.53) ! neuron part; GO:0042995 (0.51) ! cell projection; GO:0044456 (0.50) ! synapse part; GO:0043005 (0.50) ! neuron projection; GO:0016020 (0.50) ! membrane; GO:0005856 (0.50) ! cytoskeleton; GO:0015629 (0.42) ! actin cytoskeleton; GO:0014069 (0.42) ! postsynaptic density; GO:0030425 (0.38) ! dendrite; GO:0005829 (0.33) ! cytosol; GO:0005739 (0.30) ! mitochondrion; GO:0044425 (0.27) ! membrane part; GO:0032991 (0.27) ! macromolecular complex; GO:0044428 (0.26) ! nuclear part; GO:0043234 (0.25) ! protein complex; GO:0031090 (0.23) ! organelle membrane; GO:0005634 (0.23) ! nucleus; GO:0044432 (0.20) ! endoplasmic reticulum part; GO:0005783 (0.20) ! endoplasmic reticulum; GO:0005730 (0.20) ! nucleolus; GO:0031966 (0.19) ! mitochondrial membrane; GO:0005789 (0.19) ! endoplasmic reticulum membrane; GO:0044448 (0.16) ! cell cortex part; GO:0031988 (0.15) ! membrane-bounded vesicle; GO:0044463 (0.13) ! cell projection part; GO:0044421 (0.13) ! extracellular region part; GO:0005886 (0.13) ! plasma membrane; GO:1903561 (0.12) ! extracellular vesicle; GO:1902494 (0.12) ! catalytic complex; GO:0098588 (0.12) ! bounding membrane of organelle; GO:0044430 (0.12) ! cytoskeletal part; GO:0044309 (0.12) ! neuron spine; GO:0030427 (0.12) ! site of polarized growth; GO:0070062 (0.11) ! extracellular exosome; GO:0043197 (0.11) ! dendritic spine; GO:0030426 (0.11) ! growth cone; GO:0098858 (0.10) ! actin-based cell projection; GO:0098805 (0.10) ! whole membrane; GO:0044459 (0.09) ! plasma membrane part; GO:0042645 (0.09) ! mitochondrial nucleoid; GO:0030864 (0.09) ! cortical actin cytoskeleton; GO:0030175 (0.09) ! filopodium; GO:0012505 (0.09) ! endomembrane system; GO:0005951 (0.09) ! carbamoyl-phosphate synthase complex; GO:0005759 (0.09) ! mitochondrial matrix; GO:0005743 (0.09) ! mitochondrial inner membrane; GO:0005741 (0.09) ! mitochondrial outer membrane; GO:0099738 (0.07) ! cell cortex region; GO:0098590 (0.06) ! plasma membrane region; GO:0070938 (0.06) ! contractile ring; GO:0045179 (0.06) ! apical cortex; GO:0097060 (0.05) ! synaptic membrane; GO:0016023 (0.05) ! cytoplasmic, membrane-bounded vesicle; GO:0048786 (0.04) ! presynaptic active zone; GO:0045202 (0.04) ! synapse; GO:1990234 (0.03) ! transferase complex; GO:0098796 (0.03) ! membrane protein complex; GO:0044427 (0.03) ! chromosomal part; GO:0043025 (0.03) ! neuronal cell body; GO:0030134 (0.03) ! ER to Golgi transport vesicle; GO:0005887 (0.03) ! integral component of plasma membrane; GO:0005654 (0.03) ! nucleoplasm; GO:0099513 (0.02) ! polymeric cytoskeletal fiber; GO:0071546 (0.02) ! pi-body; GO:0060170 (0.02) ! ciliary membrane; GO:0045211 (0.02) ! postsynaptic membrane; GO:0036062 (0.02) ! presynaptic periactive zone; GO:0035102 (0.02) ! PRC1 complex; GO:0030027 (0.02) ! lamellipodium; GO:0008328 (0.02) ! ionotropic glutamate receptor complex; GO:0005925 (0.02) ! focal adhesion; GO:0005768 (0.02) ! endosome; GO:0000784 (0.02) ! nuclear chromosome, telomeric region; GO:1990761 (0.01) ! growth cone lamellipodium; GO:0098875 (0.01) ! epididymosome; GO:0060076 (0.01) ! excitatory synapse; GO:0051286 (0.01) ! cell tip; GO:0051285 (0.01) ! cell cortex of cell tip; GO:0044451 (0.01) ! nucleoplasm part; GO:0044326 (0.01) ! dendritic spine neck; GO:0032153 (0.01) ! cell division site; GO:0031965 (0.01) ! nuclear membrane; GO:0031901 (0.01) ! early endosome membrane; GO:0031594 (0.01) ! neuromuscular junction; GO:0031526 (0.01) ! brush border membrane; GO:0031097 (0.01) ! medial cortex; GO:0030424 (0.01) ! axon; GO:0017146 (0.01) ! NMDA selective glutamate receptor complex; GO:0016324 (0.01) ! apical plasma membrane; GO:0005942 (0.01) ! phosphatidylinositol 3-kinase complex; GO:0005911 (0.01) ! cell-cell junction; GO:0005883 (0.01) ! neurofilament; GO:0005874 (0.01) ! microtubule; GO:0005794 (0.01) ! Golgi apparatus; GO:0005694 (0.01) ! chromosome; GO:0005635 (0.01) ! nuclear envelope; GO:0005622 (0.01) ! intracellular; GO:0005615 (0.01) ! extracellular space; GO:0005576 (0.01) ! extracellular region; GO:0001917 (0.01) ! photoreceptor inner segment; GO:0001750 (0.01) ! photoreceptor outer segment; GO:0001725 (0.01) ! stress fiber; GO:0001669 (0.01) ! acrosomal vesicle; GO:0001411 (0.01) ! hyphal tip; GO:0000792 (0.01) ! heterochromatin 2 50110040-50129882 (17q21.33) Brain - Cerebellum: 129.40; Brain - Cerebellar Hemisphere: 128.30; Brain - Cortex: 37.99; Brain - Frontal Cortex (BA9): 34.44; Brain - Nucleus accumbens (basal ganglia): 32.69; Brain - Anterior cingulate cortex (BA24): 30.72; Brain - Amygdala: 24.09; Brain - Caudate (basal ganglia): 22.49; Brain - Putamen (basal ganglia): 20.32; Brain - Hippocampus: 19.82; Brain - Hypothalamus: 17.52; Brain - Substantia nigra: 10.44; Lung: 8.99; Artery - Aorta: 8.57; Brain - Spinal cord (cervical c-1): 6.31; Artery - Coronary: 6.27; Pituitary: 6.23; Prostate: 5.28; Testis: 4.72; Uterus: 4.63; Artery - Tibial: 3.76; Cervix - Ectocervix: 3.42; Esophagus - Gastroesophageal Junction: 3.35; Kidney - Cortex: 2.77; Spleen: 2.65; Ovary: 2.59; Bladder: 2.54; Cervix - Endocervix: 2.53; Vagina: 2.25; Esophagus - Muscularis: 2.19; Cells - Transformed fibroblasts: 2.05; Thyroid: 2.00; Colon - Sigmoid: 1.95; Adrenal Gland: 1.80; Adipose - Subcutaneous: 1.66; Small Intestine - Terminal Ileum: 1.47; Nerve - Tibial: 1.46; Adipose - Visceral (Omentum): 1.44; Fallopian Tube: 1.42; Colon - Transverse: 1.26; Whole Blood: 1.22; Stomach: 1.21; Heart - Atrial Appendage: 1.18; Cells - EBV-transformed lymphocytes: 0.95; Breast - Mammary Tissue: 0.91; Muscle - Skeletal: 0.81; Skin - Sun Exposed (Lower leg): 0.72; Esophagus - Mucosa: 0.71; Heart - Left Ventricle: 0.65; Liver: 0.57; Skin - Not Sun Exposed (Suprapubic): 0.55; Minor Salivary Gland: 0.31; Pancreas: 0.19; MASSKLREPVDEVFDLDLAVPETARLDSSLHKARAQLLAKGRRHRPSRSRLRDSASSAEDGEGSDGPGGKVTDGCGSPLHRLRSPLHSGPGSPAGGSFCLDPPGLRRSLDEDEPPPSPLTRYRPLHNAASHEGLAAASCSPPRSAPSSDSSPSFVRRHPRAEPHSEDDSRDASPPEPASPTIGLDKKTRRKFLDLGVTLRRASTGKSRKEKGSNRLSMGSRESVEGSGRSGGSPFLPFSWFTDSGKGSASSGSTTSPTCSPKHEGFSPKKSASQESTLSDDSTPPSSSPKIPSGPWQEAKCSYPYHTLSQSSDEFLDEPLPPVHHWTSQQVGQWLQSLNLEQYAAEFAARQVDGPQLLQLDGSKLKSLGLSNSHDRALVKRKLKEMAAAAEKERKAQEKAARQREKLRRREQEAKKS ANKRD40 Ankyrin repeat domain-containing protein 40 ANR40_HUMAN (Q6AI12-1) GO:0019899 (0.64) ! enzyme binding; GO:0044389 (0.62) ! ubiquitin-like protein ligase binding; GO:0008092 (0.62) ! cytoskeletal protein binding; GO:0030507 (0.57) ! spectrin binding; GO:0008093 (0.57) ! cytoskeletal adaptor activity; GO:0044877 (0.51) ! macromolecular complex binding; GO:0008134 (0.51) ! transcription factor binding; GO:0005048 (0.50) ! signal sequence binding; GO:0005200 (0.49) ! structural constituent of cytoskeleton; GO:0051117 (0.48) ! ATPase binding; GO:0003824 (0.33) ! catalytic activity; GO:0016740 (0.30) ! transferase activity; GO:0044325 (0.29) ! ion channel binding; GO:0019901 (0.29) ! protein kinase binding; GO:0004842 (0.26) ! ubiquitin-protein transferase activity; GO:0031625 (0.25) ! ubiquitin protein ligase binding; GO:0003676 (0.12) ! nucleic acid binding; GO:0003677 (0.10) ! DNA binding; GO:0043565 (0.08) ! sequence-specific DNA binding; GO:0001077 (0.08) ! transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0098772 (0.05) ! molecular function regulator; GO:0003712 (0.05) ! transcription cofactor activity; GO:0002039 (0.05) ! p53 binding; GO:0030234 (0.04) ! enzyme regulator activity; GO:0050839 (0.03) ! cell adhesion molecule binding; GO:0019904 (0.03) ! protein domain specific binding; GO:0019887 (0.03) ! protein kinase regulator activity; GO:0016787 (0.03) ! hydrolase activity; GO:0004672 (0.03) ! protein kinase activity; GO:0051059 (0.02) ! NF-kappaB binding; GO:0046983 (0.02) ! protein dimerization activity; GO:0042802 (0.02) ! identical protein binding; GO:0031432 (0.02) ! titin binding; GO:0030506 (0.02) ! ankyrin binding; GO:0030165 (0.02) ! PDZ domain binding; GO:0008381 (0.02) ! mechanically-gated ion channel activity; GO:0005262 (0.02) ! calcium channel activity; GO:0004674 (0.02) ! protein serine/threonine kinase activity; GO:0003723 (0.02) ! RNA binding; GO:0071889 (0.01) ! 14-3-3 protein binding; GO:0070742 (0.01) ! C2H2 zinc finger domain binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0046976 (0.01) ! histone methyltransferase activity (H3-K27 specific); GO:0046974 (0.01) ! histone methyltransferase activity (H3-K9 specific); GO:0045296 (0.01) ! cadherin binding; GO:0044822 (0.01) ! poly(A) RNA binding; GO:0044212 (0.01) ! transcription regulatory region DNA binding; GO:0043140 (0.01) ! ATP-dependent 3'-5' DNA helicase activity; GO:0042826 (0.01) ! histone deacetylase binding; GO:0042803 (0.01) ! protein homodimerization activity; GO:0042393 (0.01) ! histone binding; GO:0031072 (0.01) ! heat shock protein binding; GO:0031013 (0.01) ! troponin I binding; GO:0030296 (0.01) ! protein tyrosine kinase activator activity; GO:0030169 (0.01) ! low-density lipoprotein particle binding; GO:0019902 (0.01) ! phosphatase binding; GO:0019843 (0.01) ! rRNA binding; GO:0019208 (0.01) ! phosphatase regulator activity; GO:0016811 (0.01) ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0009378 (0.01) ! four-way junction helicase activity; GO:0008139 (0.01) ! nuclear localization sequence binding; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005178 (0.01) ! integrin binding; GO:0004871 (0.01) ! signal transducer activity; GO:0004857 (0.01) ! enzyme inhibitor activity; GO:0004540 (0.01) ! ribonuclease activity; GO:0003714 (0.01) ! transcription corepressor activity; GO:0003682 (0.01) ! chromatin binding GO:0065007 (0.82) ! biological regulation; GO:0050789 (0.78) ! regulation of biological process; GO:0050794 (0.77) ! regulation of cellular process; GO:0009987 (0.76) ! cellular process; GO:0044699 (0.72) ! single-organism process; GO:0044763 (0.66) ! single-organism cellular process; GO:0060255 (0.62) ! regulation of macromolecule metabolic process; GO:0007165 (0.62) ! signal transduction; GO:0080090 (0.61) ! regulation of primary metabolic process; GO:0031323 (0.61) ! regulation of cellular metabolic process; GO:0051179 (0.60) ! localization; GO:0048522 (0.60) ! positive regulation of cellular process; GO:0016043 (0.60) ! cellular component organization; GO:0065008 (0.58) ! regulation of biological quality; GO:0050896 (0.58) ! response to stimulus; GO:0048519 (0.58) ! negative regulation of biological process; GO:0006355 (0.58) ! regulation of transcription, DNA-templated; GO:0048523 (0.57) ! negative regulation of cellular process; GO:0010604 (0.57) ! positive regulation of macromolecule metabolic process; GO:0006810 (0.57) ! transport; GO:0031325 (0.56) ! positive regulation of cellular metabolic process; GO:0023051 (0.56) ! regulation of signaling; GO:0010646 (0.56) ! regulation of cell communication; GO:0006357 (0.56) ! regulation of transcription from RNA polymerase II promoter; GO:1902578 (0.55) ! single-organism localization; GO:0051239 (0.55) ! regulation of multicellular organismal process; GO:0051173 (0.55) ! positive regulation of nitrogen compound metabolic process; GO:0048583 (0.55) ! regulation of response to stimulus; GO:0009891 (0.55) ! positive regulation of biosynthetic process; GO:0006950 (0.55) ! response to stress; GO:1903508 (0.54) ! positive regulation of nucleic acid-templated transcription; GO:0065009 (0.54) ! regulation of molecular function; GO:0051246 (0.54) ! regulation of protein metabolic process; GO:0009966 (0.54) ! regulation of signal transduction; GO:2000026 (0.53) ! regulation of multicellular organismal development; GO:0051716 (0.53) ! cellular response to stimulus; GO:0051641 (0.53) ! cellular localization; GO:0042221 (0.53) ! response to chemical; GO:0032879 (0.53) ! regulation of localization; GO:0032268 (0.53) ! regulation of cellular protein metabolic process; GO:0002376 (0.53) ! immune system process; GO:1902531 (0.52) ! regulation of intracellular signal transduction; GO:0051247 (0.52) ! positive regulation of protein metabolic process; GO:0051049 (0.52) ! regulation of transport; GO:0048585 (0.52) ! negative regulation of response to stimulus; GO:0048584 (0.52) ! positive regulation of response to stimulus; GO:0045595 (0.52) ! regulation of cell differentiation; GO:0044802 (0.52) ! single-organism membrane organization; GO:0044765 (0.52) ! single-organism transport; GO:0044093 (0.52) ! positive regulation of molecular function; GO:0035556 (0.52) ! intracellular signal transduction; GO:0034613 (0.52) ! cellular protein localization; GO:0023057 (0.52) ! negative regulation of signaling; GO:0010941 (0.52) ! regulation of cell death; GO:0010648 (0.52) ! negative regulation of cell communication; GO:0010033 (0.52) ! response to organic substance; GO:0009628 (0.52) ! response to abiotic stimulus; GO:0009605 (0.52) ! response to external stimulus; GO:0007166 (0.52) ! cell surface receptor signaling pathway; GO:0006886 (0.52) ! intracellular protein transport; GO:1901700 (0.51) ! response to oxygen-containing compound; GO:0072661 (0.51) ! protein targeting to plasma membrane; GO:0071310 (0.51) ! cellular response to organic substance; GO:0051704 (0.51) ! multi-organism process; GO:0051241 (0.51) ! negative regulation of multicellular organismal process; GO:0051093 (0.51) ! negative regulation of developmental process; GO:0051051 (0.51) ! negative regulation of transport; GO:0051050 (0.51) ! positive regulation of transport; GO:0045596 (0.51) ! negative regulation of cell differentiation; GO:0044092 (0.51) ! negative regulation of molecular function; GO:0043207 (0.51) ! response to external biotic stimulus; GO:0043069 (0.51) ! negative regulation of programmed cell death; GO:0042981 (0.51) ! regulation of apoptotic process; GO:0034097 (0.51) ! response to cytokine; GO:0033554 (0.51) ! cellular response to stress; GO:0033157 (0.51) ! regulation of intracellular protein transport; GO:0031347 (0.51) ! regulation of defense response; GO:0009968 (0.51) ! negative regulation of signal transduction; GO:0009719 (0.51) ! response to endogenous stimulus; GO:0009266 (0.51) ! response to temperature stimulus; GO:0002682 (0.51) ! regulation of immune system process; GO:1903707 (0.50) ! negative regulation of hemopoiesis; GO:1901652 (0.50) ! response to peptide; GO:0071222 (0.50) ! cellular response to lipopolysaccharide; GO:0070423 (0.50) ! nucleotide-binding oligomerization domain containing signaling pathway; GO:0051101 (0.50) ! regulation of DNA binding; GO:0051100 (0.50) ! negative regulation of binding; GO:0051091 (0.50) ! positive regulation of sequence-specific DNA binding transcription factor activity; GO:0050851 (0.50) ! antigen receptor-mediated signaling pathway; GO:0045637 (0.50) ! regulation of myeloid cell differentiation; GO:0044764 (0.50) ! multi-organism cellular process; GO:0044403 (0.50) ! symbiosis, encompassing mutualism through parasitism; GO:0043433 (0.50) ! negative regulation of sequence-specific DNA binding transcription factor activity; GO:0043331 (0.50) ! response to dsRNA; GO:0042994 (0.50) ! cytoplasmic sequestering of transcription factor; GO:0042347 (0.50) ! negative regulation of NF-kappaB import into nucleus; GO:0038093 (0.50) ! Fc receptor signaling pathway; GO:0032376 (0.50) ! positive regulation of cholesterol transport; GO:0010883 (0.50) ! regulation of lipid storage; GO:0010874 (0.50) ! regulation of cholesterol efflux; GO:0010743 (0.50) ! regulation of macrophage derived foam cell differentiation; GO:0009612 (0.50) ! response to mechanical stimulus; GO:0009409 (0.50) ! response to cold; GO:0008593 (0.50) ! regulation of Notch signaling pathway; GO:0008283 (0.50) ! cell proliferation; GO:0002224 (0.50) ! toll-like receptor signaling pathway; GO:0002220 (0.50) ! innate immune response activating cell surface receptor signaling pathway; GO:0016192 (0.49) ! vesicle-mediated transport; GO:0048193 (0.48) ! Golgi vesicle transport; GO:0006888 (0.47) ! ER to Golgi vesicle-mediated transport; GO:0044767 (0.40) ! single-organism developmental process; GO:0032501 (0.36) ! multicellular organismal process; GO:0048856 (0.35) ! anatomical structure development; GO:0010628 (0.35) ! positive regulation of gene expression; GO:0044707 (0.34) ! single-multicellular organism process; GO:0006996 (0.34) ! organelle organization; GO:0051128 (0.33) ! regulation of cellular component organization; GO:0042391 (0.32) ! regulation of membrane potential; GO:0022607 (0.32) ! cellular component assembly; GO:0051130 (0.30) ! positive regulation of cellular component organization; GO:0048646 (0.30) ! anatomical structure formation involved in morphogenesis; GO:0044057 (0.30) ! regulation of system process; GO:0033043 (0.30) ! regulation of organelle organization; GO:0032970 (0.30) ! regulation of actin filament-based process; GO:0007010 (0.30) ! cytoskeleton organization; GO:2001257 (0.29) ! regulation of cation channel activity; GO:2000021 (0.29) ! regulation of ion homeostasis; GO:1904064 (0.29) ! positive regulation of cation transmembrane transport; GO:1901016 (0.29) ! regulation of potassium ion transmembrane transporter activity; GO:0098910 (0.29) ! regulation of atrial cardiac muscle cell action potential; GO:0051597 (0.29) ! response to methylmercury; GO:0033365 (0.29) ! protein localization to organelle; GO:0032414 (0.29) ! positive regulation of ion transmembrane transporter activity; GO:0030913 (0.29) ! paranodal junction assembly; GO:0002027 (0.29) ! regulation of heart rate; GO:2001259 (0.28) ! positive regulation of cation channel activity; GO:1901021 (0.28) ! positive regulation of calcium ion transmembrane transporter activity; GO:1901018 (0.28) ! positive regulation of potassium ion transmembrane transporter activity; GO:0098907 (0.28) ! regulation of SA node cell action potential; GO:0086091 (0.28) ! regulation of heart rate by cardiac conduction; GO:0086046 (0.28) ! membrane depolarization during SA node cell action potential; GO:0086005 (0.28) ! ventricular cardiac muscle cell action potential; GO:0070972 (0.28) ! protein localization to endoplasmic reticulum; GO:0060307 (0.28) ! regulation of ventricular cardiac muscle cell membrane repolarization; GO:0050821 (0.28) ! protein stabilization; GO:0036371 (0.28) ! protein localization to T-tubule; GO:0036309 (0.28) ! protein localization to M-band; GO:0034394 (0.28) ! protein localization to cell surface; GO:0033292 (0.28) ! T-tubule organization; GO:0032940 (0.28) ! secretion by cell; GO:0010881 (0.28) ! regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; GO:0010638 (0.28) ! positive regulation of organelle organization; GO:0003283 (0.28) ! atrial septum development; GO:0045199 (0.27) ! maintenance of epithelial cell apical/basal polarity; GO:0006887 (0.27) ! exocytosis; GO:0071704 (0.21) ! organic substance metabolic process; GO:0044238 (0.21) ! primary metabolic process; GO:0044237 (0.21) ! cellular metabolic process; GO:0044260 (0.18) ! cellular macromolecule metabolic process; GO:0043412 (0.14) ! macromolecule modification; GO:0019538 (0.13) ! protein metabolic process; GO:0006464 (0.12) ! cellular protein modification process; GO:0048869 (0.10) ! cellular developmental process; GO:0045893 (0.09) ! positive regulation of transcription, DNA-templated; GO:0042592 (0.09) ! homeostatic process; GO:0009653 (0.09) ! anatomical structure morphogenesis; GO:0045944 (0.08) ! positive regulation of transcription from RNA polymerase II promoter; GO:0022414 (0.08) ! reproductive process; GO:0006807 (0.08) ! nitrogen compound metabolic process; GO:1901360 (0.07) ! organic cyclic compound metabolic process; GO:0044702 (0.07) ! single organism reproductive process; GO:0034641 (0.07) ! cellular nitrogen compound metabolic process; GO:0019725 (0.07) ! cellular homeostasis; GO:0006796 (0.07) ! phosphate-containing compound metabolic process; GO:0006725 (0.07) ! cellular aromatic compound metabolic process; GO:0098771 (0.06) ! inorganic ion homeostasis; GO:0090304 (0.06) ! nucleic acid metabolic process; GO:0050790 (0.06) ! regulation of catalytic activity; GO:0031399 (0.06) ! regulation of protein modification process; GO:0031324 (0.06) ! negative regulation of cellular metabolic process; GO:0030001 (0.06) ! metal ion transport; GO:0010605 (0.06) ! negative regulation of macromolecule metabolic process; GO:0006952 (0.06) ! defense response; GO:0006468 (0.06) ! protein phosphorylation; GO:0003008 (0.06) ! system process; GO:2000113 (0.05) ! negative regulation of cellular macromolecule biosynthetic process; GO:0051960 (0.05) ! regulation of nervous system development; GO:0051253 (0.05) ! negative regulation of RNA metabolic process; GO:0051240 (0.05) ! positive regulation of multicellular organismal process; GO:0050877 (0.05) ! neurological system process; GO:0045087 (0.05) ! innate immune response; GO:0042325 (0.05) ! regulation of phosphorylation; GO:0032989 (0.05) ! cellular component morphogenesis; GO:0030154 (0.05) ! cell differentiation; GO:0030030 (0.05) ! cell projection organization; GO:0022402 (0.05) ! cell cycle process; GO:0010629 (0.05) ! negative regulation of gene expression; GO:0006874 (0.05) ! cellular calcium ion homeostasis; GO:1902589 (0.04) ! single-organism organelle organization; GO:1901575 (0.04) ! organic substance catabolic process; GO:0051480 (0.04) ! regulation of cytosolic calcium ion concentration; GO:0051094 (0.04) ! positive regulation of developmental process; GO:0048812 (0.04) ! neuron projection morphogenesis; GO:0048589 (0.04) ! developmental growth; GO:0045892 (0.04) ! negative regulation of transcription, DNA-templated; GO:0044710 (0.04) ! single-organism metabolic process; GO:0044708 (0.04) ! single-organism behavior; GO:0044248 (0.04) ! cellular catabolic process; GO:0044087 (0.04) ! regulation of cellular component biogenesis; GO:0032270 (0.04) ! positive regulation of cellular protein metabolic process; GO:0016567 (0.04) ! protein ubiquitination; GO:0016070 (0.04) ! RNA metabolic process; GO:0009967 (0.04) ! positive regulation of signal transduction; GO:0007600 (0.04) ! sensory perception; GO:0007276 (0.04) ! gamete generation; GO:0006828 (0.04) ! manganese ion transport; GO:0006259 (0.04) ! DNA metabolic process; GO:0001932 (0.04) ! regulation of protein phosphorylation; GO:1901576 (0.03) ! organic substance biosynthetic process; GO:0060828 (0.03) ! regulation of canonical Wnt signaling pathway; GO:0051962 (0.03) ! positive regulation of nervous system development; GO:0051726 (0.03) ! regulation of cell cycle; GO:0050808 (0.03) ! synapse organization; GO:0048675 (0.03) ! axon extension; GO:0048513 (0.03) ! animal organ development; GO:0045937 (0.03) ! positive regulation of phosphate metabolic process; GO:0045859 (0.03) ! regulation of protein kinase activity; GO:0045664 (0.03) ! regulation of neuron differentiation; GO:0044249 (0.03) ! cellular biosynthetic process; GO:0043046 (0.03) ! DNA methylation involved in gamete generation; GO:0042787 (0.03) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0042127 (0.03) ! regulation of cell proliferation; GO:0040008 (0.03) ! regulation of growth; GO:0034587 (0.03) ! piRNA metabolic process; GO:0031401 (0.03) ! positive regulation of protein modification process; GO:0022603 (0.03) ! regulation of anatomical structure morphogenesis; GO:0009888 (0.03) ! tissue development; GO:0007613 (0.03) ! memory; GO:0007605 (0.03) ! sensory perception of sound; GO:0007283 (0.03) ! spermatogenesis; GO:0007275 (0.03) ! multicellular organism development; GO:0007140 (0.03) ! male meiosis; GO:0000122 (0.03) ! negative regulation of transcription from RNA polymerase II promoter; GO:2000027 (0.02) ! regulation of organ morphogenesis; GO:1903047 (0.02) ! mitotic cell cycle process; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:1901605 (0.02) ! alpha-amino acid metabolic process; GO:1900074 (0.02) ! negative regulation of neuromuscular synaptic transmission; GO:0097193 (0.02) ! intrinsic apoptotic signaling pathway; GO:0071709 (0.02) ! membrane assembly; GO:0070050 (0.02) ! neuron cellular homeostasis; GO:0051345 (0.02) ! positive regulation of hydrolase activity; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0048468 (0.02) ! cell development; GO:0045887 (0.02) ! positive regulation of synaptic growth at neuromuscular junction; GO:0045786 (0.02) ! negative regulation of cell cycle; GO:0045597 (0.02) ! positive regulation of cell differentiation; GO:0044712 (0.02) ! single-organism catabolic process; GO:0043933 (0.02) ! macromolecular complex subunit organization; GO:0043161 (0.02) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043063 (0.02) ! intercellular bridge organization; GO:0042692 (0.02) ! muscle cell differentiation; GO:0040011 (0.02) ! locomotion; GO:0035239 (0.02) ! tube morphogenesis; GO:0032101 (0.02) ! regulation of response to external stimulus; GO:0031344 (0.02) ! regulation of cell projection organization; GO:0030162 (0.02) ! regulation of proteolysis; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0019233 (0.02) ! sensory perception of pain; GO:0018193 (0.02) ! peptidyl-amino acid modification; GO:0010639 (0.02) ! negative regulation of organelle organization; GO:0010564 (0.02) ! regulation of cell cycle process; GO:0009887 (0.02) ! organ morphogenesis; GO:0009886 (0.02) ! post-embryonic morphogenesis; GO:0009792 (0.02) ! embryo development ending in birth or egg hatching; GO:0007614 (0.02) ! short-term memory; GO:0007528 (0.02) ! neuromuscular junction development; GO:0007389 (0.02) ! pattern specification process; GO:0007346 (0.02) ! regulation of mitotic cell cycle; GO:0007338 (0.02) ! single fertilization; GO:0007249 (0.02) ! I-kappaB kinase/NF-kappaB signaling; GO:0007219 (0.02) ! Notch signaling pathway; GO:0006954 (0.02) ! inflammatory response; GO:0006928 (0.02) ! movement of cell or subcellular component; GO:0006897 (0.02) ! endocytosis; GO:0006816 (0.02) ! calcium ion transport; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0002009 (0.02) ! morphogenesis of an epithelium; GO:0001934 (0.02) ! positive regulation of protein phosphorylation; GO:0000226 (0.02) ! microtubule cytoskeleton organization; GO:0000209 (0.02) ! protein polyubiquitination; GO:2001233 (0.01) ! regulation of apoptotic signaling pathway; GO:2000045 (0.01) ! regulation of G1/S transition of mitotic cell cycle; GO:1990126 (0.01) ! retrograde transport, endosome to plasma membrane; GO:1904059 (0.01) ! regulation of locomotor rhythm; GO:1901991 (0.01) ! negative regulation of mitotic cell cycle phase transition; GO:1901796 (0.01) ! regulation of signal transduction by p53 class mediator; GO:1900006 (0.01) ! positive regulation of dendrite development; GO:0097150 (0.01) ! neuronal stem cell population maintenance; GO:0090316 (0.01) ! positive regulation of intracellular protein transport; GO:0090263 (0.01) ! positive regulation of canonical Wnt signaling pathway; GO:0090090 (0.01) ! negative regulation of canonical Wnt signaling pathway; GO:0086065 (0.01) ! cell communication involved in cardiac conduction; GO:0072671 (0.01) ! mitochondria-associated ubiquitin-dependent protein catabolic process; GO:0071900 (0.01) ! regulation of protein serine/threonine kinase activity; GO:0071630 (0.01) ! nucleus-associated proteasomal ubiquitin-dependent protein catabolic process; GO:0071476 (0.01) ! cellular hypotonic response; GO:0071417 (0.01) ! cellular response to organonitrogen compound; GO:0071407 (0.01) ! cellular response to organic cyclic compound; GO:0071363 (0.01) ! cellular response to growth factor stimulus; GO:0071345 (0.01) ! cellular response to cytokine stimulus; GO:0071260 (0.01) ! cellular response to mechanical stimulus; GO:0070588 (0.01) ! calcium ion transmembrane transport; GO:0070509 (0.01) ! calcium ion import; GO:0060429 (0.01) ! epithelium development; GO:0060047 (0.01) ! heart contraction; GO:0051896 (0.01) ! regulation of protein kinase B signaling; GO:0051640 (0.01) ! organelle localization; GO:0051570 (0.01) ! regulation of histone H3-K9 methylation; GO:0051494 (0.01) ! negative regulation of cytoskeleton organization; GO:0051438 (0.01) ! regulation of ubiquitin-protein transferase activity; GO:0051259 (0.01) ! protein oligomerization; GO:0051092 (0.01) ! positive regulation of NF-kappaB transcription factor activity; GO:0051052 (0.01) ! regulation of DNA metabolic process; GO:0050974 (0.01) ! detection of mechanical stimulus involved in sensory perception; GO:0050688 (0.01) ! regulation of defense response to virus; GO:0048936 (0.01) ! peripheral nervous system neuron axonogenesis; GO:0048814 (0.01) ! regulation of dendrite morphogenesis; GO:0048754 (0.01) ! branching morphogenesis of an epithelial tube; GO:0048514 (0.01) ! blood vessel morphogenesis; GO:0048477 (0.01) ! oogenesis; GO:0048259 (0.01) ! regulation of receptor-mediated endocytosis; GO:0046500 (0.01) ! S-adenosylmethionine metabolic process; GO:0046498 (0.01) ! S-adenosylhomocysteine metabolic process; GO:0046330 (0.01) ! positive regulation of JNK cascade; GO:0045860 (0.01) ! positive regulation of protein kinase activity; GO:0045787 (0.01) ! positive regulation of cell cycle; GO:0045665 (0.01) ! negative regulation of neuron differentiation; GO:0045314 (0.01) ! regulation of compound eye photoreceptor development; GO:0045022 (0.01) ! early endosome to late endosome transport; GO:0043547 (0.01) ! positive regulation of GTPase activity; GO:0043392 (0.01) ! negative regulation of DNA binding; GO:0043123 (0.01) ! positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043086 (0.01) ! negative regulation of catalytic activity; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0042742 (0.01) ! defense response to bacterium; GO:0042493 (0.01) ! response to drug; GO:0042246 (0.01) ! tissue regeneration; GO:0038180 (0.01) ! nerve growth factor signaling pathway; GO:0038061 (0.01) ! NIK/NF-kappaB signaling; GO:0035907 (0.01) ! dorsal aorta development; GO:0035317 (0.01) ! imaginal disc-derived wing hair organization; GO:0035307 (0.01) ! positive regulation of protein dephosphorylation; GO:0035295 (0.01) ! tube development; GO:0035107 (0.01) ! appendage morphogenesis; GO:0034654 (0.01) ! nucleobase-containing compound biosynthetic process; GO:0034645 (0.01) ! cellular macromolecule biosynthetic process; GO:0033048 (0.01) ! negative regulation of mitotic sister chromatid segregation; GO:0032956 (0.01) ! regulation of actin cytoskeleton organization; GO:0032846 (0.01) ! positive regulation of homeostatic process; GO:0032535 (0.01) ! regulation of cellular component size; GO:0032436 (0.01) ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0032271 (0.01) ! regulation of protein polymerization; GO:0032088 (0.01) ! negative regulation of NF-kappaB transcription factor activity; GO:0031667 (0.01) ! response to nutrient levels; GO:0031032 (0.01) ! actomyosin structure organization; GO:0030855 (0.01) ! epithelial cell differentiation; GO:0030725 (0.01) ! germline ring canal formation; GO:0030433 (0.01) ! ER-associated ubiquitin-dependent protein catabolic process; GO:0030334 (0.01) ! regulation of cell migration; GO:0022407 (0.01) ! regulation of cell-cell adhesion; GO:0021654 (0.01) ! rhombomere boundary formation; GO:0021514 (0.01) ! ventral spinal cord interneuron differentiation; GO:0018345 (0.01) ! protein palmitoylation; GO:0016570 (0.01) ! histone modification; GO:0010996 (0.01) ! response to auditory stimulus; GO:0010921 (0.01) ! regulation of phosphatase activity; GO:0010171 (0.01) ! body morphogenesis; GO:0010038 (0.01) ! response to metal ion; GO:0009725 (0.01) ! response to hormone; GO:0009636 (0.01) ! response to toxic substance; GO:0009615 (0.01) ! response to virus; GO:0009416 (0.01) ! response to light stimulus; GO:0009408 (0.01) ! response to heat; GO:0008544 (0.01) ! epidermis development; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008219 (0.01) ! cell death; GO:0007638 (0.01) ! mechanosensory behavior; GO:0007626 (0.01) ! locomotory behavior; GO:0007616 (0.01) ! long-term memory; GO:0007612 (0.01) ! learning; GO:0007560 (0.01) ! imaginal disc morphogenesis; GO:0007507 (0.01) ! heart development; GO:0007411 (0.01) ! axon guidance; GO:0007399 (0.01) ! nervous system development; GO:0007391 (0.01) ! dorsal closure; GO:0007231 (0.01) ! osmosensory signaling pathway; GO:0007204 (0.01) ! positive regulation of cytosolic calcium ion concentration; GO:0007155 (0.01) ! cell adhesion; GO:0007093 (0.01) ! mitotic cell cycle checkpoint; GO:0007050 (0.01) ! cell cycle arrest; GO:0007015 (0.01) ! actin filament organization; GO:0006650 (0.01) ! glycerophospholipid metabolic process; GO:0006543 (0.01) ! glutamine catabolic process; GO:0006537 (0.01) ! glutamate biosynthetic process; GO:0006479 (0.01) ! protein methylation; GO:0006396 (0.01) ! RNA processing; GO:0006310 (0.01) ! DNA recombination; GO:0006302 (0.01) ! double-strand break repair; GO:0003012 (0.01) ! muscle system process; GO:0003002 (0.01) ! regionalization; GO:0002252 (0.01) ! immune effector process; GO:0002244 (0.01) ! hematopoietic progenitor cell differentiation; GO:0001964 (0.01) ! startle response; GO:0001936 (0.01) ! regulation of endothelial cell proliferation; GO:0001933 (0.01) ! negative regulation of protein phosphorylation; GO:0001889 (0.01) ! liver development; GO:0001817 (0.01) ! regulation of cytokine production; GO:0001701 (0.01) ! in utero embryonic development; GO:0001667 (0.01) ! ameboidal-type cell migration; GO:0001558 (0.01) ! regulation of cell growth; GO:0001101 (0.01) ! response to acid chemical; GO:0000904 (0.01) ! cell morphogenesis involved in differentiation GO:0044464 (0.99) ! cell part; GO:0044424 (0.94) ! intracellular part; GO:0043229 (0.86) ! intracellular organelle; GO:0043227 (0.80) ! membrane-bounded organelle; GO:0043231 (0.79) ! intracellular membrane-bounded organelle; GO:0005737 (0.77) ! cytoplasm; GO:0044444 (0.66) ! cytoplasmic part; GO:0005634 (0.65) ! nucleus; GO:0016020 (0.63) ! membrane; GO:0044425 (0.56) ! membrane part; GO:0005886 (0.55) ! plasma membrane; GO:0032991 (0.53) ! macromolecular complex; GO:0044459 (0.51) ! plasma membrane part; GO:0044422 (0.51) ! organelle part; GO:0043234 (0.51) ! protein complex; GO:0016021 (0.46) ! integral component of membrane; GO:0005829 (0.43) ! cytosol; GO:0044446 (0.41) ! intracellular organelle part; GO:0097458 (0.34) ! neuron part; GO:0042995 (0.29) ! cell projection; GO:0098590 (0.28) ! plasma membrane region; GO:0044428 (0.27) ! nuclear part; GO:0005887 (0.27) ! integral component of plasma membrane; GO:0030054 (0.26) ! cell junction; GO:0043005 (0.25) ! neuron projection; GO:1902494 (0.24) ! catalytic complex; GO:0031410 (0.24) ! cytoplasmic vesicle; GO:0005622 (0.24) ! intracellular; GO:0005654 (0.23) ! nucleoplasm; GO:0043232 (0.22) ! intracellular non-membrane-bounded organelle; GO:0031988 (0.21) ! membrane-bounded vesicle; GO:0016023 (0.20) ! cytoplasmic, membrane-bounded vesicle; GO:0000151 (0.20) ! ubiquitin ligase complex; GO:0044463 (0.18) ! cell projection part; GO:0044456 (0.18) ! synapse part; GO:0009986 (0.17) ! cell surface; GO:0016324 (0.16) ! apical plasma membrane; GO:0097060 (0.14) ! synaptic membrane; GO:0031090 (0.14) ! organelle membrane; GO:0005856 (0.14) ! cytoskeleton; GO:0044431 (0.13) ! Golgi apparatus part; GO:0045202 (0.12) ! synapse; GO:0033267 (0.12) ! axon part; GO:0033256 (0.12) ! I-kappaB/NF-kappaB complex; GO:0005912 (0.12) ! adherens junction; GO:0045211 (0.11) ! postsynaptic membrane; GO:0044432 (0.11) ! endoplasmic reticulum part; GO:0044297 (0.11) ! cell body; GO:0005794 (0.11) ! Golgi apparatus; GO:0005783 (0.11) ! endoplasmic reticulum; GO:0000139 (0.11) ! Golgi membrane; GO:0044449 (0.10) ! contractile fiber part; GO:0042470 (0.10) ! melanosome; GO:0070013 (0.08) ! intracellular organelle lumen; GO:0043235 (0.08) ! receptor complex; GO:0042383 (0.08) ! sarcolemma; GO:0031672 (0.08) ! A band; GO:0031253 (0.08) ! cell projection membrane; GO:0030018 (0.08) ! Z disc; GO:0005770 (0.08) ! late endosome; GO:0005739 (0.08) ! mitochondrion; GO:0071944 (0.07) ! cell periphery; GO:0044295 (0.07) ! axonal growth cone; GO:0033257 (0.07) ! Bcl3/NF-kappaB2 complex; GO:0032589 (0.07) ! neuron projection membrane; GO:0032584 (0.07) ! growth cone membrane; GO:0032421 (0.07) ! stereocilium bundle; GO:0031430 (0.07) ! M band; GO:0030659 (0.07) ! cytoplasmic vesicle membrane; GO:0030424 (0.07) ! axon; GO:0030027 (0.07) ! lamellipodium; GO:0016323 (0.07) ! basolateral plasma membrane; GO:0005789 (0.07) ! endoplasmic reticulum membrane; GO:0005764 (0.07) ! lysosome; GO:0005576 (0.07) ! extracellular region; GO:0002193 (0.07) ! MAML1-RBP-Jkappa- ICN1 complex; GO:0001669 (0.07) ! acrosomal vesicle; GO:0098796 (0.05) ! membrane protein complex; GO:0044430 (0.05) ! cytoskeletal part; GO:0044429 (0.05) ! mitochondrial part; GO:0044421 (0.05) ! extracellular region part; GO:0043034 (0.05) ! costamere; GO:0042734 (0.05) ! presynaptic membrane; GO:0005911 (0.05) ! cell-cell junction; GO:1902495 (0.04) ! transmembrane transporter complex; GO:0098805 (0.04) ! whole membrane; GO:0097422 (0.04) ! tubular endosome; GO:0048471 (0.04) ! perinuclear region of cytoplasm; GO:0045171 (0.04) ! intercellular bridge; GO:0045121 (0.04) ! membrane raft; GO:0043025 (0.04) ! neuronal cell body; GO:0030425 (0.04) ! dendrite; GO:0030133 (0.04) ! transport vesicle; GO:0015629 (0.04) ! actin cytoskeleton; GO:0005769 (0.04) ! early endosome; GO:0005759 (0.04) ! mitochondrial matrix; GO:1990060 (0.03) ! maltose transport complex; GO:0055052 (0.03) ! ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; GO:0045111 (0.03) ! intermediate filament cytoskeleton; GO:0043197 (0.03) ! dendritic spine; GO:0035003 (0.03) ! subapical complex; GO:0032996 (0.03) ! Bcl3-Bcl10 complex; GO:0032591 (0.03) ! dendritic spine membrane; GO:0032426 (0.03) ! stereocilium tip; GO:0032420 (0.03) ! stereocilium; GO:0031941 (0.03) ! filamentous actin; GO:0030673 (0.03) ! axolemma; GO:0030660 (0.03) ! Golgi-associated vesicle membrane; GO:0030315 (0.03) ! T-tubule; GO:0030288 (0.03) ! outer membrane-bounded periplasmic space; GO:0030139 (0.03) ! endocytic vesicle; GO:0016529 (0.03) ! sarcoplasmic reticulum; GO:0016363 (0.03) ! nuclear matrix; GO:0014731 (0.03) ! spectrin-associated cytoskeleton; GO:0014704 (0.03) ! intercalated disc; GO:0012505 (0.03) ! endomembrane system; GO:0009897 (0.03) ! external side of plasma membrane; GO:0008540 (0.03) ! proteasome regulatory particle, base subcomplex; GO:0005903 (0.03) ! brush border; GO:0005902 (0.03) ! microvillus; GO:0005838 (0.03) ! proteasome regulatory particle; GO:0005796 (0.03) ! Golgi lumen; GO:0005788 (0.03) ! endoplasmic reticulum lumen; GO:0005694 (0.03) ! chromosome; GO:0000502 (0.03) ! proteasome complex; GO:0071546 (0.02) ! pi-body; GO:0044427 (0.02) ! chromosomal part; GO:0043195 (0.02) ! terminal bouton; GO:0036062 (0.02) ! presynaptic periactive zone; GO:0031594 (0.02) ! neuromuscular junction; GO:0098791 (0.01) ! Golgi subcompartment; GO:0070062 (0.01) ! extracellular exosome; GO:0045179 (0.01) ! apical cortex; GO:0045177 (0.01) ! apical part of cell; GO:0044454 (0.01) ! nuclear chromosome part; GO:0044451 (0.01) ! nucleoplasm part; GO:0043296 (0.01) ! apical junction complex; GO:0036266 (0.01) ! Cdc48p-Npl4p-Vms1p AAA ATPase complex; GO:0034703 (0.01) ! cation channel complex; GO:0031461 (0.01) ! cullin-RING ubiquitin ligase complex; GO:0030496 (0.01) ! midbody; GO:0030017 (0.01) ! sarcomere; GO:0014069 (0.01) ! postsynaptic density; GO:0005929 (0.01) ! cilium; GO:0005925 (0.01) ! focal adhesion; GO:0005913 (0.01) ! cell-cell adherens junction; GO:0005813 (0.01) ! centrosome; GO:0005774 (0.01) ! vacuolar membrane; GO:0000785 (0.01) ! chromatin; GO:0000776 (0.01) ! kinetochore GO:0005515 ! protein binding 3 GO:0005515 ! protein binding 50693190-50707924 (17q21.33) High: stomach 2 (glandular cells);stomach 1 (glandular cells);seminal vesicle (glandular cells);colon (endothelial cells; glandular cells; peripheral nerve/ganglion);gallbladder (glandular cells);esophagus (squamous epithelial cells);kidney (cells in glomeruli; cells in tubules);testis (cells in seminiferous ducts);caudate (glial cells);tonsil (germinal center cells; non-germinal center cells; squamous epithelial cells);thyroid gland (glandular cells);epididymis (glandular cells);adrenal gland (glandular cells);endometrium 1 (cells in endometrial stroma; glandular cells);endometrium 2 (glandular cells);salivary gland (glandular cells);pancreas (exocrine glandular cells; islets of Langerhans);cerebral cortex (endothelial cells; glial cells; neuronal cells);vagina (squamous epithelial cells);lymph node (germinal center cells; non-germinal center cells);placenta (decidual cells; trophoblastic cells);hippocampus (glial cells; neuronal cells);bronchus (respiratory epithelial cells);parathyroid gland (glandular cells);urinary bladder (urothelial cells);appendix (glandular cells; lymphoid tissue);breast (glandular cells);rectum (glandular cells);prostate (glandular cells);cervix, uterine (glandular cells; squamous epithelial cells);duodenum (glandular cells);cerebellum (cells in granular layer; cells in molecular layer; Purkinje cells);spleen (cells in red pulp; cells in white pulp);bone marrow (hematopoietic cells);small intestine (glandular cells);nasopharynx (respiratory epithelial cells);lung (macrophages; pneumocytes);ovary (follicle cells);oral mucosa (squamous epithelial cells);skin 2 (epidermal cells);Medium: testis (Leydig cells);caudate (neuronal cells);fallopian tube (glandular cells);soft tissue 1 (adipocytes; chondrocytes; fibroblasts; peripheral nerve);soft tissue 2 (fibroblasts; peripheral nerve);breast (myoepithelial cells);skin 1 (fibroblasts; keratinocytes; Langerhans; melanocytes);smooth muscle (smooth muscle cells);Low: soft tissue 2 (adipocytes);skeletal muscle (myocytes);endometrium 2 (cells in endometrial stroma);heart muscle (myocytes);ovary (ovarian stroma cells);liver (bile duct cells); Brain - Spinal cord (cervical c-1): 197.80; Brain - Substantia nigra: 113.60; Brain - Hippocampus: 73.81; Nerve - Tibial: 67.70; Brain - Putamen (basal ganglia): 66.50; Brain - Amygdala: 63.30; Muscle - Skeletal: 59.04; Brain - Hypothalamus: 57.57; Brain - Caudate (basal ganglia): 50.84; Artery - Tibial: 48.09; Brain - Cerebellar Hemisphere: 47.72; Adipose - Subcutaneous: 47.52; Colon - Sigmoid: 44.85; Brain - Cerebellum: 44.44; Uterus: 44.05; Bladder: 43.69; Cervix - Ectocervix: 42.92; Esophagus - Muscularis: 42.48; Brain - Frontal Cortex (BA9): 41.18; Brain - Nucleus accumbens (basal ganglia): 40.39; Adipose - Visceral (Omentum): 39.59; Esophagus - Gastroesophageal Junction: 38.53; Cells - Transformed fibroblasts: 38.36; Artery - Coronary: 37.69; Cervix - Endocervix: 37.63; Breast - Mammary Tissue: 36.41; Artery - Aorta: 36.09; Fallopian Tube: 35.75; Brain - Cortex: 35.33; Lung: 33.29; Brain - Anterior cingulate cortex (BA24): 33.24; Ovary: 31.67; Thyroid: 29.28; Prostate: 25.90; Vagina: 25.37; Colon - Transverse: 22.83; Adrenal Gland: 22.68; Spleen: 22.29; Skin - Sun Exposed (Lower leg): 19.69; Minor Salivary Gland: 18.99; Skin - Not Sun Exposed (Suprapubic): 18.60; Cells - EBV-transformed lymphocytes: 18.14; Small Intestine - Terminal Ileum: 17.79; Testis: 17.55; Stomach: 16.54; Heart - Atrial Appendage: 16.20; Esophagus - Mucosa: 15.85; Heart - Left Ventricle: 15.73; Pituitary: 15.13; Kidney - Cortex: 13.69; Pancreas: 11.10; Liver: 8.64; Whole Blood: 2.91; MNALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHWACKRNHGQVVSYLLKSGADKEILTTKGEMPVQLTSRREIRKIMGVEEEDDDDDDDDNLPQLKKESELPFVPNYLANPAFPFIYTPTAEDSAQMQNGGPSTPPASPPADGSPPLLPPGEPPLLGTFPRDHTSLALVQNGDVSAPSAILRTPESTKPGPVCQPPVSQSRSLFSSVPSKPPMSLEPQNGTYAGPAPAFQPFFFTGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVCCCELGVNPDQVEKIRKLPNTLLRKDKDVARLQDFQELELVLMISENNFLFRNAASTLTERPCYNRRASKLTY C17orf67 Uncharacterized protein C17orf67 CQ067_HUMAN (Q0P5P2-1) GO:0043169 (0.58) ! cation binding; GO:0004112 (0.58) ! cyclic-nucleotide phosphodiesterase activity; GO:0032561 (0.48) ! guanyl ribonucleotide binding; GO:0030551 (0.48) ! cyclic nucleotide binding GO:0046068 (0.48) ! cGMP metabolic process; GO:0009214 (0.48) ! cyclic nucleotide catabolic process; GO:0009154 (0.48) ! purine ribonucleotide catabolic process; GO:2000243 (0.37) ! positive regulation of reproductive process; GO:1900542 (0.37) ! regulation of purine nucleotide metabolic process; GO:0090075 (0.37) ! relaxation of muscle; GO:0071902 (0.37) ! positive regulation of protein serine/threonine kinase activity; GO:0060281 (0.37) ! regulation of oocyte development; GO:0055117 (0.37) ! regulation of cardiac muscle contraction; GO:0050868 (0.37) ! negative regulation of T cell activation; GO:0050672 (0.37) ! negative regulation of lymphocyte proliferation; GO:0045988 (0.37) ! negative regulation of striated muscle contraction; GO:0045822 (0.37) ! negative regulation of heart contraction; GO:0043902 (0.37) ! positive regulation of multi-organism process; GO:0043410 (0.37) ! positive regulation of MAPK cascade; GO:0043405 (0.37) ! regulation of MAP kinase activity; GO:0042129 (0.37) ! regulation of T cell proliferation; GO:0030799 (0.37) ! regulation of cyclic nucleotide metabolic process; GO:0014742 (0.37) ! positive regulation of muscle hypertrophy; GO:0010720 (0.37) ! positive regulation of cell development; GO:0010611 (0.37) ! regulation of cardiac muscle hypertrophy GO:0044464 (1.00) ! cell part; GO:0044424 (0.87) ! intracellular part; GO:0044444 (0.73) ! cytoplasmic part; GO:0005829 (0.53) ! cytosol; GO:0043226 (0.47) ! organelle; GO:0005737 (0.47) ! cytoplasm; GO:0043229 (0.33) ! intracellular organelle; GO:0016020 (0.33) ! membrane; GO:0044446 (0.27) ! intracellular organelle part; GO:0043227 (0.27) ! membrane-bounded organelle; GO:0097458 (0.20) ! neuron part; GO:0043231 (0.20) ! intracellular membrane-bounded organelle; GO:0005886 (0.20) ! plasma membrane; GO:0098590 (0.13) ! plasma membrane region; GO:0044421 (0.13) ! extracellular region part; GO:0043232 (0.13) ! intracellular non-membrane-bounded organelle; GO:0043204 (0.13) ! perikaryon; GO:0043025 (0.13) ! neuronal cell body; GO:0032991 (0.13) ! macromolecular complex; GO:0005759 (0.13) ! mitochondrial matrix; GO:0005739 (0.13) ! mitochondrion; GO:0005634 (0.13) ! nucleus; GO:0072372 (0.07) ! primary cilium; GO:0070062 (0.07) ! extracellular exosome; GO:0048471 (0.07) ! perinuclear region of cytoplasm; GO:0045121 (0.07) ! membrane raft; GO:0042734 (0.07) ! presynaptic membrane; GO:0022625 (0.07) ! cytosolic large ribosomal subunit; GO:0016324 (0.07) ! apical plasma membrane; GO:0012505 (0.07) ! endomembrane system; GO:0009507 (0.07) ! chloroplast; GO:0005891 (0.07) ! voltage-gated calcium channel complex; GO:0005856 (0.07) ! cytoskeleton; GO:0005840 (0.07) ! ribosome; GO:0005813 (0.07) ! centrosome; GO:0005794 (0.07) ! Golgi apparatus; GO:0005783 (0.07) ! endoplasmic reticulum; GO:0005654 (0.07) ! nucleoplasm; GO:0005622 (0.07) ! intracellular; GO:0005615 (0.07) ! extracellular space GO:0005515 ! protein binding GO:0005576 ! extracellular region 2 GO:0005515 ! protein binding 56791913-56838773 (17q22) Uterus: 5.22; Testis: 5.08; Spleen: 4.93; Nerve - Tibial: 4.40; Prostate: 4.36; Ovary: 3.82; Cervix - Ectocervix: 3.81; Cervix - Endocervix: 3.79; Vagina: 3.75; Fallopian Tube: 3.56; Thyroid: 3.24; Lung: 3.03; Cells - EBV-transformed lymphocytes: 2.90; Small Intestine - Terminal Ileum: 2.83; Colon - Sigmoid: 2.81; Pituitary: 2.80; Bladder: 2.73; Artery - Aorta: 2.70; Esophagus - Muscularis: 2.51; Esophagus - Gastroesophageal Junction: 2.46; Adipose - Visceral (Omentum): 2.40; Artery - Coronary: 2.39; Brain - Hypothalamus: 2.32; Breast - Mammary Tissue: 2.26; Brain - Cerebellar Hemisphere: 2.15; Brain - Cerebellum: 2.12; Brain - Spinal cord (cervical c-1): 2.08; Adipose - Subcutaneous: 1.90; Liver: 1.87; Artery - Tibial: 1.85; Colon - Transverse: 1.73; Cells - Transformed fibroblasts: 1.71; Brain - Frontal Cortex (BA9): 1.48; Pancreas: 1.38; Brain - Anterior cingulate cortex (BA24): 1.37; Minor Salivary Gland: 1.37; Brain - Substantia nigra: 1.36; Stomach: 1.35; Brain - Cortex: 1.35; Esophagus - Mucosa: 1.34; Brain - Hippocampus: 1.31; Brain - Nucleus accumbens (basal ganglia): 1.23; Brain - Amygdala: 1.18; Skin - Sun Exposed (Lower leg): 1.09; Skin - Not Sun Exposed (Suprapubic): 1.05; Brain - Caudate (basal ganglia): 1.05; Kidney - Cortex: 0.96; Whole Blood: 0.89; Brain - Putamen (basal ganglia): 0.83; Heart - Atrial Appendage: 0.81; Adrenal Gland: 0.49; Heart - Left Ventricle: 0.48; Muscle - Skeletal: 0.33; MASFKLADSVWEDSLSKRQRNQGRMKTLPVLVLSLTLLTVFSETSPILTEKQAKQLLRSRRQDRPSKPGFPDEPMREYMHHLLALEHRAEEQFLEHWLNPHCKPHCDRNRIHPV CUEDC1 CUE domain-containing protein 1 CUED1_HUMAN (Q9NWM3-1) GO:0022892 (0.35) ! substrate-specific transporter activity; GO:0019899 (0.32) ! enzyme binding; GO:0008331 (0.26) ! high voltage-gated calcium channel activity; GO:0005102 (0.23) ! receptor binding; GO:0042393 (0.20) ! histone binding; GO:0046872 (0.18) ! metal ion binding; GO:0035325 (0.17) ! Toll-like receptor binding; GO:0019900 (0.17) ! kinase binding; GO:0030234 (0.15) ! enzyme regulator activity; GO:0051879 (0.12) ! Hsp90 protein binding; GO:0044822 (0.12) ! poly(A) RNA binding; GO:0019904 (0.12) ! protein domain specific binding; GO:0008565 (0.12) ! protein transporter activity; GO:0008536 (0.12) ! Ran GTPase binding; GO:0008270 (0.12) ! zinc ion binding; GO:0008139 (0.12) ! nuclear localization sequence binding; GO:0004871 (0.11) ! signal transducer activity; GO:0003824 (0.11) ! catalytic activity; GO:0005096 (0.09) ! GTPase activator activity; GO:0005509 (0.07) ! calcium ion binding; GO:0046982 (0.06) ! protein heterodimerization activity; GO:0032183 (0.06) ! SUMO binding; GO:0031625 (0.06) ! ubiquitin protein ligase binding; GO:0031624 (0.06) ! ubiquitin conjugating enzyme binding; GO:0017025 (0.06) ! TBP-class protein binding; GO:0017022 (0.06) ! myosin binding; GO:0008601 (0.06) ! protein phosphatase type 2A regulator activity; GO:0005150 (0.06) ! interleukin-1, Type I receptor binding; GO:0004722 (0.06) ! protein serine/threonine phosphatase activity; GO:0003823 (0.06) ! antigen binding; GO:0004702 (0.05) ! receptor signaling protein serine/threonine kinase activity GO:0009987 (0.94) ! cellular process; GO:0065007 (0.58) ! biological regulation; GO:0044237 (0.58) ! cellular metabolic process; GO:0006796 (0.55) ! phosphate-containing compound metabolic process; GO:0050794 (0.52) ! regulation of cellular process; GO:0016310 (0.52) ! phosphorylation; GO:0044763 (0.40) ! single-organism cellular process; GO:0022402 (0.28) ! cell cycle process; GO:0080090 (0.27) ! regulation of primary metabolic process; GO:0050896 (0.27) ! response to stimulus; GO:0031325 (0.27) ! positive regulation of cellular metabolic process; GO:0010604 (0.27) ! positive regulation of macromolecule metabolic process; GO:0007267 (0.24) ! cell-cell signaling; GO:0045944 (0.23) ! positive regulation of transcription from RNA polymerase II promoter; GO:0033365 (0.23) ! protein localization to organelle; GO:0007165 (0.23) ! signal transduction; GO:0006950 (0.22) ! response to stress; GO:0036269 (0.20) ! swimming behavior; GO:0007274 (0.20) ! neuromuscular synaptic transmission; GO:0001966 (0.20) ! thigmotaxis; GO:0065008 (0.18) ! regulation of biological quality; GO:0000077 (0.18) ! DNA damage checkpoint; GO:0009968 (0.17) ! negative regulation of signal transduction; GO:1902589 (0.15) ! single-organism organelle organization; GO:0048869 (0.15) ! cellular developmental process; GO:0035556 (0.15) ! intracellular signal transduction; GO:0007010 (0.15) ! cytoskeleton organization; GO:1902532 (0.13) ! negative regulation of intracellular signal transduction; GO:0036010 (0.13) ! protein localization to endosome; GO:0090307 (0.12) ! mitotic spindle assembly; GO:0075733 (0.12) ! intracellular transport of virus; GO:0040001 (0.12) ! establishment of mitotic spindle localization; GO:0031291 (0.12) ! Ran protein signal transduction; GO:0030953 (0.12) ! astral microtubule organization; GO:0019054 (0.12) ! modulation by virus of host process; GO:0007080 (0.12) ! mitotic metaphase plate congression; GO:0007079 (0.12) ! mitotic chromosome movement towards spindle pole; GO:0006610 (0.12) ! ribosomal protein import into nucleus; GO:0006607 (0.12) ! NLS-bearing protein import into nucleus; GO:0006309 (0.12) ! apoptotic DNA fragmentation; GO:0000060 (0.12) ! protein import into nucleus, translocation; GO:0000059 (0.12) ! protein import into nucleus, docking; GO:0031399 (0.11) ! regulation of protein modification process; GO:0030111 (0.10) ! regulation of Wnt signaling pathway; GO:0030036 (0.10) ! actin cytoskeleton organization; GO:0030855 (0.09) ! epithelial cell differentiation; GO:0086010 (0.07) ! membrane depolarization during action potential; GO:0046580 (0.07) ! negative regulation of Ras protein signal transduction; GO:2001241 (0.06) ! positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; GO:1903538 (0.06) ! regulation of meiotic cell cycle process involved in oocyte maturation; GO:0070262 (0.06) ! peptidyl-serine dephosphorylation; GO:0051754 (0.06) ! meiotic sister chromatid cohesion, centromeric; GO:0051306 (0.06) ! mitotic sister chromatid separation; GO:0051232 (0.06) ! meiotic spindle elongation; GO:0045899 (0.06) ! positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; GO:0042518 (0.06) ! negative regulation of tyrosine phosphorylation of Stat3 protein; GO:0034047 (0.06) ! regulation of protein phosphatase type 2A activity; GO:0030308 (0.06) ! negative regulation of cell growth; GO:0030155 (0.06) ! regulation of cell adhesion; GO:0019932 (0.06) ! second-messenger-mediated signaling; GO:0016567 (0.06) ! protein ubiquitination; GO:0010265 (0.06) ! SCF complex assembly; GO:0010033 (0.06) ! response to organic substance; GO:0008380 (0.06) ! RNA splicing; GO:0008298 (0.06) ! intracellular mRNA localization; GO:0007533 (0.06) ! mating type switching; GO:0007143 (0.06) ! female meiotic division; GO:0007084 (0.06) ! mitotic nuclear envelope reassembly; GO:0006672 (0.06) ! ceramide metabolic process; GO:0006275 (0.06) ! regulation of DNA replication; GO:0000188 (0.06) ! inactivation of MAPK activity; GO:0000184 (0.06) ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; GO:0000086 (0.06) ! G2/M transition of mitotic cell cycle; GO:0033235 (0.05) ! positive regulation of protein sumoylation; GO:0045321 (0.04) ! leukocyte activation; GO:0030178 (0.04) ! negative regulation of Wnt signaling pathway; GO:0006954 (0.04) ! inflammatory response GO:0044424 (1.00) ! intracellular part; GO:0043227 (0.90) ! membrane-bounded organelle; GO:0005634 (0.85) ! nucleus; GO:0044446 (0.81) ! intracellular organelle part; GO:0005737 (0.75) ! cytoplasm; GO:0044428 (0.66) ! nuclear part; GO:0016020 (0.60) ! membrane; GO:0043234 (0.58) ! protein complex; GO:0070062 (0.56) ! extracellular exosome; GO:0044444 (0.56) ! cytoplasmic part; GO:0005643 (0.54) ! nuclear pore; GO:0005829 (0.36) ! cytosol; GO:0005654 (0.30) ! nucleoplasm; GO:0044459 (0.24) ! plasma membrane part; GO:1902494 (0.23) ! catalytic complex; GO:0034399 (0.23) ! nuclear periphery; GO:0031965 (0.23) ! nuclear membrane; GO:0005635 (0.23) ! nuclear envelope; GO:0005886 (0.20) ! plasma membrane; GO:0071782 (0.15) ! endoplasmic reticulum tubular network; GO:0044611 (0.15) ! nuclear pore inner ring; GO:0031235 (0.15) ! intrinsic component of the cytoplasmic side of the plasma membrane; GO:0015630 (0.15) ! microtubule cytoskeleton; GO:0005739 (0.15) ! mitochondrion; GO:0005694 (0.15) ! chromosome; GO:0000775 (0.15) ! chromosome, centromeric region; GO:0000159 (0.15) ! protein phosphatase type 2A complex; GO:0048471 (0.10) ! perinuclear region of cytoplasm; GO:0016604 (0.10) ! nuclear body; GO:0045323 (0.09) ! interleukin-1 receptor complex; GO:0045092 (0.09) ! interleukin-18 receptor complex; GO:0032154 (0.07) ! cleavage furrow; GO:0031461 (0.07) ! cullin-RING ubiquitin ligase complex; GO:0005938 (0.07) ! cell cortex; GO:0005794 (0.07) ! Golgi apparatus 2 57861243-57955323 (17q22) High: cerebellum (Purkinje cells);stomach 1 (glandular cells);Medium: stomach 2 (glandular cells);seminal vesicle (glandular cells);colon (endothelial cells; glandular cells; peripheral nerve/ganglion);gallbladder (glandular cells);esophagus (squamous epithelial cells);kidney (cells in tubules);testis (cells in seminiferous ducts; Leydig cells);caudate (neuronal cells);tonsil (germinal center cells; squamous epithelial cells);thyroid gland (glandular cells);epididymis (glandular cells);adrenal gland (glandular cells);endometrium 1 (glandular cells);endometrium 2 (glandular cells);salivary gland (glandular cells);smooth muscle (smooth muscle cells);heart muscle (myocytes);pancreas (exocrine glandular cells);cerebral cortex (endothelial cells; neuronal cells; neuropil);vagina (squamous epithelial cells);lymph node (non-germinal center cells);placenta (decidual cells; trophoblastic cells);hippocampus (neuronal cells);bronchus (respiratory epithelial cells);parathyroid gland (glandular cells);skeletal muscle (myocytes);urinary bladder (urothelial cells);appendix (glandular cells; lymphoid tissue);liver (bile duct cells; hepatocytes);rectum (glandular cells);prostate (glandular cells);cervix, uterine (glandular cells; squamous epithelial cells);duodenum (glandular cells);cerebellum (cells in granular layer; cells in molecular layer);fallopian tube (glandular cells);bone marrow (hematopoietic cells);soft tissue 2 (fibroblasts; peripheral nerve);skin 2 (epidermal cells);small intestine (glandular cells);soft tissue 1 (adipocytes; fibroblasts; peripheral nerve);nasopharynx (respiratory epithelial cells);lung (macrophages; pneumocytes);ovary (follicle cells);oral mucosa (squamous epithelial cells);skin 1 (fibroblasts; keratinocytes; melanocytes);breast (glandular cells; myoepithelial cells);Low: lymph node (germinal center cells);hippocampus (glial cells);caudate (glial cells);spleen (cells in red pulp; cells in white pulp);skin 1 (Langerhans);soft tissue 2 (adipocytes);tonsil (non-germinal center cells);endometrium 1 (cells in endometrial stroma);endometrium 2 (cells in endometrial stroma);breast (adipocytes);soft tissue 1 (chondrocytes);ovary (ovarian stroma cells);cerebral cortex (glial cells);kidney (cells in glomeruli); Colon - Sigmoid: 57.87; Esophagus - Muscularis: 57.63; Esophagus - Gastroesophageal Junction: 55.70; Fallopian Tube: 48.62; Cervix - Endocervix: 48.50; Uterus: 43.13; Prostate: 43.07; Nerve - Tibial: 41.99; Artery - Tibial: 39.90; Cervix - Ectocervix: 39.56; Bladder: 39.04; Pituitary: 38.66; Brain - Spinal cord (cervical c-1): 38.15; Artery - Coronary: 38.02; Thyroid: 33.91; Vagina: 33.61; Artery - Aorta: 32.90; Muscle - Skeletal: 32.63; Minor Salivary Gland: 31.04; Lung: 30.79; Cells - Transformed fibroblasts: 29.62; Adipose - Subcutaneous: 28.40; Esophagus - Mucosa: 28.32; Brain - Substantia nigra: 25.25; Breast - Mammary Tissue: 24.50; Brain - Hypothalamus: 23.76; Adrenal Gland: 23.74; Colon - Transverse: 23.15; Kidney - Cortex: 22.78; Stomach: 21.86; Heart - Atrial Appendage: 21.77; Adipose - Visceral (Omentum): 20.26; Brain - Cerebellum: 19.53; Heart - Left Ventricle: 18.29; Brain - Putamen (basal ganglia): 18.21; Brain - Cerebellar Hemisphere: 17.83; Brain - Hippocampus: 17.49; Spleen: 17.43; Brain - Caudate (basal ganglia): 17.12; Brain - Amygdala: 16.70; Skin - Sun Exposed (Lower leg): 15.48; Brain - Nucleus accumbens (basal ganglia): 15.37; Ovary: 13.84; Brain - Cortex: 13.81; Brain - Anterior cingulate cortex (BA24): 12.93; Brain - Frontal Cortex (BA9): 12.70; Skin - Not Sun Exposed (Suprapubic): 12.39; Pancreas: 11.31; Small Intestine - Terminal Ileum: 10.85; Whole Blood: 6.69; Testis: 5.17; Liver: 3.29; Cells - EBV-transformed lymphocytes: 0.42; MTSLFRRSSSGSGGGGTAGARGGGGGTAAPQELNNSRPARQVRRLEFNQAMDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEGGGSSGGVYEDSSDSEDSIPPEILERTLEPDSSDEEPPPVYSPPAYHMHVFDRPYPLAPPTPPPRIDALGSGAPTSQRRYRNWNPPLLGNLPDDFLRILPQQLDSIQGNAGGPKPGSGEGCPPAMAGPGPGDQESRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESQKSKSSSVAVGNDFGFSSPVPGTGDANPAVSEDALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAASTANLLDDVEGHACDEDFRGRRQEAPKVEEGLREGQ C17orf47 Uncharacterized protein C17orf47 CQ047_HUMAN (Q8NEP4-1) GO:1901363 (0.37) ! heterocyclic compound binding; GO:0097159 (0.37) ! organic cyclic compound binding; GO:0003676 (0.35) ! nucleic acid binding; GO:0003824 (0.21) ! catalytic activity; GO:0022892 (0.18) ! substrate-specific transporter activity; GO:0015075 (0.17) ! ion transmembrane transporter activity; GO:0008324 (0.16) ! cation transmembrane transporter activity; GO:0005216 (0.16) ! ion channel activity; GO:0005261 (0.15) ! cation channel activity; GO:0046873 (0.13) ! metal ion transmembrane transporter activity; GO:0008092 (0.13) ! cytoskeletal protein binding; GO:0022843 (0.12) ! voltage-gated cation channel activity; GO:0016740 (0.12) ! transferase activity; GO:0015085 (0.12) ! calcium ion transmembrane transporter activity; GO:0005262 (0.11) ! calcium channel activity; GO:0005198 (0.11) ! structural molecule activity; GO:0005245 (0.10) ! voltage-gated calcium channel activity; GO:0003779 (0.09) ! actin binding; GO:0044877 (0.07) ! macromolecular complex binding; GO:0019899 (0.07) ! enzyme binding; GO:0016787 (0.07) ! hydrolase activity; GO:0016772 (0.07) ! transferase activity, transferring phosphorus-containing groups; GO:0008331 (0.06) ! high voltage-gated calcium channel activity; GO:0098772 (0.05) ! molecular function regulator; GO:0032403 (0.05) ! protein complex binding; GO:0008190 (0.05) ! eukaryotic initiation factor 4E binding; GO:0008017 (0.05) ! microtubule binding; GO:0005201 (0.05) ! extracellular matrix structural constituent; GO:0051015 (0.04) ! actin filament binding; GO:0016887 (0.04) ! ATPase activity; GO:0004871 (0.04) ! signal transducer activity; GO:0004842 (0.04) ! ubiquitin-protein transferase activity; GO:0004672 (0.04) ! protein kinase activity; GO:0003723 (0.04) ! RNA binding; GO:0003677 (0.04) ! DNA binding; GO:0099600 (0.03) ! transmembrane receptor activity; GO:0097110 (0.03) ! scaffold protein binding; GO:0044822 (0.03) ! poly(A) RNA binding; GO:0043169 (0.03) ! cation binding; GO:0042623 (0.03) ! ATPase activity, coupled; GO:0017016 (0.03) ! Ras GTPase binding; GO:0008332 (0.03) ! low voltage-gated calcium channel activity; GO:0008307 (0.03) ! structural constituent of muscle; GO:0005096 (0.03) ! GTPase activator activity; GO:0004674 (0.03) ! protein serine/threonine kinase activity; GO:0003682 (0.03) ! chromatin binding; GO:0001055 (0.03) ! RNA polymerase II activity; GO:0097493 (0.02) ! structural molecule activity conferring elasticity; GO:0051371 (0.02) ! muscle alpha-actinin binding; GO:0030507 (0.02) ! spectrin binding; GO:0019904 (0.02) ! protein domain specific binding; GO:0019901 (0.02) ! protein kinase binding; GO:0017048 (0.02) ! Rho GTPase binding; GO:0016788 (0.02) ! hydrolase activity, acting on ester bonds; GO:0015079 (0.02) ! potassium ion transmembrane transporter activity; GO:0008093 (0.02) ! cytoskeletal adaptor activity; GO:0005543 (0.02) ! phospholipid binding; GO:0005509 (0.02) ! calcium ion binding; GO:0005200 (0.02) ! structural constituent of cytoskeleton; GO:0005102 (0.02) ! receptor binding; GO:0004930 (0.02) ! G-protein coupled receptor activity; GO:0003777 (0.02) ! microtubule motor activity; GO:0003712 (0.02) ! transcription cofactor activity; GO:0003700 (0.02) ! transcription factor activity, sequence-specific DNA binding; GO:0001076 (0.02) ! transcription factor activity, RNA polymerase II transcription factor binding; GO:0071949 (0.01) ! FAD binding; GO:0070011 (0.01) ! peptidase activity, acting on L-amino acid peptides; GO:0051011 (0.01) ! microtubule minus-end binding; GO:0050839 (0.01) ! cell adhesion molecule binding; GO:0048495 (0.01) ! Roundabout binding; GO:0047485 (0.01) ! protein N-terminus binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0044325 (0.01) ! ion channel binding; GO:0044212 (0.01) ! transcription regulatory region DNA binding; GO:0043621 (0.01) ! protein self-association; GO:0043565 (0.01) ! sequence-specific DNA binding; GO:0043140 (0.01) ! ATP-dependent 3'-5' DNA helicase activity; GO:0043015 (0.01) ! gamma-tubulin binding; GO:0042826 (0.01) ! histone deacetylase binding; GO:0042802 (0.01) ! identical protein binding; GO:0042800 (0.01) ! histone methyltransferase activity (H3-K4 specific); GO:0042626 (0.01) ! ATPase activity, coupled to transmembrane movement of substances; GO:0034596 (0.01) ! phosphatidylinositol phosphate 4-phosphatase activity; GO:0031625 (0.01) ! ubiquitin protein ligase binding; GO:0031491 (0.01) ! nucleosome binding; GO:0030165 (0.01) ! PDZ domain binding; GO:0019905 (0.01) ! syntaxin binding; GO:0017137 (0.01) ! Rab GTPase binding; GO:0017049 (0.01) ! GTP-Rho binding; GO:0016709 (0.01) ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; GO:0015291 (0.01) ! secondary active transmembrane transporter activity; GO:0009378 (0.01) ! four-way junction helicase activity; GO:0008201 (0.01) ! heparin binding; GO:0008134 (0.01) ! transcription factor binding; GO:0008022 (0.01) ! protein C-terminus binding; GO:0008013 (0.01) ! beta-catenin binding; GO:0005546 (0.01) ! phosphatidylinositol-4,5-bisphosphate binding; GO:0005544 (0.01) ! calcium-dependent phospholipid binding; GO:0005528 (0.01) ! FK506 binding; GO:0005524 (0.01) ! ATP binding; GO:0005522 (0.01) ! profilin binding; GO:0005516 (0.01) ! calmodulin binding; GO:0005254 (0.01) ! chloride channel activity; GO:0005249 (0.01) ! voltage-gated potassium channel activity; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0004713 (0.01) ! protein tyrosine kinase activity; GO:0004702 (0.01) ! receptor signaling protein serine/threonine kinase activity; GO:0004439 (0.01) ! phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; GO:0004438 (0.01) ! phosphatidylinositol-3-phosphatase activity; GO:0003918 (0.01) ! DNA topoisomerase type II (ATP-hydrolyzing) activity; GO:0003755 (0.01) ! peptidyl-prolyl cis-trans isomerase activity; GO:0003690 (0.01) ! double-stranded DNA binding; GO:0001104 (0.01) ! RNA polymerase II transcription cofactor activity; GO:0000981 (0.01) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0009987 (0.59) ! cellular process; GO:0044699 (0.51) ! single-organism process; GO:0065007 (0.50) ! biological regulation; GO:0044763 (0.42) ! single-organism cellular process; GO:0050789 (0.39) ! regulation of biological process; GO:0050794 (0.38) ! regulation of cellular process; GO:0044767 (0.27) ! single-organism developmental process; GO:0016043 (0.26) ! cellular component organization; GO:0065008 (0.25) ! regulation of biological quality; GO:0032501 (0.24) ! multicellular organismal process; GO:0008152 (0.22) ! metabolic process; GO:0071704 (0.21) ! organic substance metabolic process; GO:0051179 (0.21) ! localization; GO:0044238 (0.21) ! primary metabolic process; GO:0044237 (0.21) ! cellular metabolic process; GO:0048856 (0.20) ! anatomical structure development; GO:0043170 (0.20) ! macromolecule metabolic process; GO:0051234 (0.19) ! establishment of localization; GO:0050896 (0.19) ! response to stimulus; GO:0044707 (0.19) ! single-multicellular organism process; GO:0044260 (0.19) ! cellular macromolecule metabolic process; GO:0048518 (0.18) ! positive regulation of biological process; GO:0006810 (0.18) ! transport; GO:0048522 (0.17) ! positive regulation of cellular process; GO:0006996 (0.17) ! organelle organization; GO:0048519 (0.16) ! negative regulation of biological process; GO:0007165 (0.16) ! signal transduction; GO:0019222 (0.14) ! regulation of metabolic process; GO:0006950 (0.14) ! response to stress; GO:0006464 (0.14) ! cellular protein modification process; GO:0080090 (0.13) ! regulation of primary metabolic process; GO:0060255 (0.13) ! regulation of macromolecule metabolic process; GO:0042391 (0.13) ! regulation of membrane potential; GO:0009653 (0.13) ! anatomical structure morphogenesis; GO:0007010 (0.13) ! cytoskeleton organization; GO:1902589 (0.12) ! single-organism organelle organization; GO:1901360 (0.12) ! organic cyclic compound metabolic process; GO:0048869 (0.12) ! cellular developmental process; GO:0034641 (0.12) ! cellular nitrogen compound metabolic process; GO:0031323 (0.12) ! regulation of cellular metabolic process; GO:0090304 (0.11) ! nucleic acid metabolic process; GO:0051716 (0.11) ! cellular response to stimulus; GO:0051239 (0.11) ! regulation of multicellular organismal process; GO:0051128 (0.11) ! regulation of cellular component organization; GO:0031326 (0.11) ! regulation of cellular biosynthetic process; GO:0019219 (0.11) ! regulation of nucleobase-containing compound metabolic process; GO:2000112 (0.10) ! regulation of cellular macromolecule biosynthetic process; GO:0048523 (0.10) ! negative regulation of cellular process; GO:0044700 (0.10) ! single organism signaling; GO:0033554 (0.10) ! cellular response to stress; GO:0010468 (0.10) ! regulation of gene expression; GO:0007166 (0.10) ! cell surface receptor signaling pathway; GO:0007154 (0.10) ! cell communication; GO:1901576 (0.09) ! organic substance biosynthetic process; GO:0086010 (0.09) ! membrane depolarization during action potential; GO:0051641 (0.09) ! cellular localization; GO:0044249 (0.09) ! cellular biosynthetic process; GO:0032879 (0.09) ! regulation of localization; GO:0022607 (0.09) ! cellular component assembly; GO:0007267 (0.09) ! cell-cell signaling; GO:0006974 (0.09) ! cellular response to DNA damage stimulus; GO:0006811 (0.09) ! ion transport; GO:0006355 (0.09) ! regulation of transcription, DNA-templated; GO:0006259 (0.09) ! DNA metabolic process; GO:0048646 (0.08) ! anatomical structure formation involved in morphogenesis; GO:0033043 (0.08) ! regulation of organelle organization; GO:0031325 (0.08) ! positive regulation of cellular metabolic process; GO:0030036 (0.08) ! actin cytoskeleton organization; GO:0016070 (0.08) ! RNA metabolic process; GO:0010605 (0.08) ! negative regulation of macromolecule metabolic process; GO:0010604 (0.08) ! positive regulation of macromolecule metabolic process; GO:0009059 (0.08) ! macromolecule biosynthetic process; GO:0007017 (0.08) ! microtubule-based process; GO:0006812 (0.08) ! cation transport; GO:1902680 (0.07) ! positive regulation of RNA biosynthetic process; GO:0051649 (0.07) ! establishment of localization in cell; GO:0051052 (0.07) ! regulation of DNA metabolic process; GO:0051049 (0.07) ! regulation of transport; GO:0050793 (0.07) ! regulation of developmental process; GO:0048731 (0.07) ! system development; GO:0048513 (0.07) ! animal organ development; GO:0043933 (0.07) ! macromolecular complex subunit organization; GO:0034654 (0.07) ! nucleobase-containing compound biosynthetic process; GO:0034645 (0.07) ! cellular macromolecule biosynthetic process; GO:0023051 (0.07) ! regulation of signaling; GO:0022402 (0.07) ! cell cycle process; GO:0018193 (0.07) ! peptidyl-amino acid modification; GO:0016071 (0.07) ! mRNA metabolic process; GO:0010646 (0.07) ! regulation of cell communication; GO:0010629 (0.07) ! negative regulation of gene expression; GO:0010628 (0.07) ! positive regulation of gene expression; GO:0008104 (0.07) ! protein localization; GO:0006928 (0.07) ! movement of cell or subcellular component; GO:0006816 (0.07) ! calcium ion transport; GO:0006396 (0.07) ! RNA processing; GO:0006281 (0.07) ! DNA repair; GO:0003008 (0.07) ! system process; GO:2000026 (0.06) ! regulation of multicellular organismal development; GO:1903047 (0.06) ! mitotic cell cycle process; GO:0060627 (0.06) ! regulation of vesicle-mediated transport; GO:0051130 (0.06) ! positive regulation of cellular component organization; GO:0048583 (0.06) ! regulation of response to stimulus; GO:0048524 (0.06) ! positive regulation of viral process; GO:0045595 (0.06) ! regulation of cell differentiation; GO:0032989 (0.06) ! cellular component morphogenesis; GO:0030030 (0.06) ! cell projection organization; GO:0022604 (0.06) ! regulation of cell morphogenesis; GO:0022414 (0.06) ! reproductive process; GO:0019827 (0.06) ! stem cell population maintenance; GO:0007475 (0.06) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.06) ! open tracheal system development; GO:0007169 (0.06) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0006366 (0.06) ! transcription from RNA polymerase II promoter; GO:0000398 (0.06) ! mRNA splicing, via spliceosome; GO:0000226 (0.06) ! microtubule cytoskeleton organization; GO:1903530 (0.05) ! regulation of secretion by cell; GO:0071702 (0.05) ! organic substance transport; GO:0051960 (0.05) ! regulation of nervous system development; GO:0050434 (0.05) ! positive regulation of viral transcription; GO:0046907 (0.05) ! intracellular transport; GO:0044087 (0.05) ! regulation of cellular component biogenesis; GO:0042795 (0.05) ! snRNA transcription from RNA polymerase II promoter; GO:0042221 (0.05) ! response to chemical; GO:0035019 (0.05) ! somatic stem cell population maintenance; GO:0034613 (0.05) ! cellular protein localization; GO:0033120 (0.05) ! positive regulation of RNA splicing; GO:0031047 (0.05) ! gene silencing by RNA; GO:0017196 (0.05) ! N-terminal peptidyl-methionine acetylation; GO:0010769 (0.05) ! regulation of cell morphogenesis involved in differentiation; GO:0008543 (0.05) ! fibroblast growth factor receptor signaling pathway; GO:0008016 (0.05) ! regulation of heart contraction; GO:0006461 (0.05) ! protein complex assembly; GO:0006370 (0.05) ! 7-methylguanosine mRNA capping; GO:0006368 (0.05) ! transcription elongation from RNA polymerase II promoter; GO:0006367 (0.05) ! transcription initiation from RNA polymerase II promoter; GO:0006353 (0.05) ! DNA-templated transcription, termination; GO:0006298 (0.05) ! mismatch repair; GO:0006283 (0.05) ! transcription-coupled nucleotide-excision repair; GO:0001172 (0.05) ! transcription, RNA-templated; GO:0000018 (0.05) ! regulation of DNA recombination; GO:1903305 (0.04) ! regulation of regulated secretory pathway; GO:0090066 (0.04) ! regulation of anatomical structure size; GO:0070925 (0.04) ! organelle assembly; GO:0051493 (0.04) ! regulation of cytoskeleton organization; GO:0051240 (0.04) ! positive regulation of multicellular organismal process; GO:0050770 (0.04) ! regulation of axonogenesis; GO:0048870 (0.04) ! cell motility; GO:0048812 (0.04) ! neuron projection morphogenesis; GO:0044710 (0.04) ! single-organism metabolic process; GO:0044702 (0.04) ! single organism reproductive process; GO:0044089 (0.04) ! positive regulation of cellular component biogenesis; GO:0042592 (0.04) ! homeostatic process; GO:0040008 (0.04) ! regulation of growth; GO:0035556 (0.04) ! intracellular signal transduction; GO:0035239 (0.04) ! tube morphogenesis; GO:0034622 (0.04) ! cellular macromolecular complex assembly; GO:0034220 (0.04) ! ion transmembrane transport; GO:0032886 (0.04) ! regulation of microtubule-based process; GO:0031032 (0.04) ! actomyosin structure organization; GO:0016567 (0.04) ! protein ubiquitination; GO:0016192 (0.04) ! vesicle-mediated transport; GO:0015031 (0.04) ! protein transport; GO:0010927 (0.04) ! cellular component assembly involved in morphogenesis; GO:0010720 (0.04) ! positive regulation of cell development; GO:0010639 (0.04) ! negative regulation of organelle organization; GO:0009966 (0.04) ! regulation of signal transduction; GO:0009628 (0.04) ! response to abiotic stimulus; GO:0009605 (0.04) ! response to external stimulus; GO:0007275 (0.04) ! multicellular organism development; GO:0007268 (0.04) ! chemical synaptic transmission; GO:2000021 (0.03) ! regulation of ion homeostasis; GO:1902580 (0.03) ! single-organism cellular localization; GO:1902531 (0.03) ! regulation of intracellular signal transduction; GO:0098771 (0.03) ! inorganic ion homeostasis; GO:0070509 (0.03) ! calcium ion import; GO:0061024 (0.03) ! membrane organization; GO:0051726 (0.03) ! regulation of cell cycle; GO:0051491 (0.03) ! positive regulation of filopodium assembly; GO:0051270 (0.03) ! regulation of cellular component movement; GO:0051246 (0.03) ! regulation of protein metabolic process; GO:0050877 (0.03) ! neurological system process; GO:0050790 (0.03) ! regulation of catalytic activity; GO:0048813 (0.03) ! dendrite morphogenesis; GO:0048729 (0.03) ! tissue morphogenesis; GO:0048468 (0.03) ! cell development; GO:0046331 (0.03) ! lateral inhibition; GO:0045956 (0.03) ! positive regulation of calcium ion-dependent exocytosis; GO:0045934 (0.03) ! negative regulation of nucleobase-containing compound metabolic process; GO:0045773 (0.03) ! positive regulation of axon extension; GO:0045214 (0.03) ! sarcomere organization; GO:0044719 (0.03) ! regulation of imaginal disc-derived wing size; GO:0043623 (0.03) ! cellular protein complex assembly; GO:0042787 (0.03) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0040007 (0.03) ! growth; GO:0040005 (0.03) ! chitin-based cuticle attachment to epithelium; GO:0035149 (0.03) ! lumen formation, open tracheal system; GO:0035147 (0.03) ! branch fusion, open tracheal system; GO:0030716 (0.03) ! oocyte fate determination; GO:0030154 (0.03) ! cell differentiation; GO:0030003 (0.03) ! cellular cation homeostasis; GO:0016477 (0.03) ! cell migration; GO:0016319 (0.03) ! mushroom body development; GO:0016204 (0.03) ! determination of muscle attachment site; GO:0016203 (0.03) ! muscle attachment; GO:0016199 (0.03) ! axon midline choice point recognition; GO:0010038 (0.03) ! response to metal ion; GO:0009888 (0.03) ! tissue development; GO:0008362 (0.03) ! chitin-based embryonic cuticle biosynthetic process; GO:0007610 (0.03) ! behavior; GO:0007423 (0.03) ! sensory organ development; GO:0007409 (0.03) ! axonogenesis; GO:0007026 (0.03) ! negative regulation of microtubule depolymerization; GO:0007015 (0.03) ! actin filament organization; GO:0006952 (0.03) ! defense response; GO:0006936 (0.03) ! muscle contraction; GO:0006886 (0.03) ! intracellular protein transport; GO:0006796 (0.03) ! phosphate-containing compound metabolic process; GO:0006357 (0.03) ! regulation of transcription from RNA polymerase II promoter; GO:0002376 (0.03) ! immune system process; GO:0002027 (0.03) ! regulation of heart rate; GO:0001578 (0.03) ! microtubule bundle formation; GO:0001508 (0.03) ! action potential; GO:1903046 (0.02) ! meiotic cell cycle process; GO:1902275 (0.02) ! regulation of chromatin organization; GO:0098910 (0.02) ! regulation of atrial cardiac muscle cell action potential; GO:0098660 (0.02) ! inorganic ion transmembrane transport; GO:0072661 (0.02) ! protein targeting to plasma membrane; GO:0060371 (0.02) ! regulation of atrial cardiac muscle cell membrane depolarization; GO:0060341 (0.02) ! regulation of cellular localization; GO:0055008 (0.02) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.02) ! cardiac myofibril assembly; GO:0051704 (0.02) ! multi-organism process; GO:0051656 (0.02) ! establishment of organelle localization; GO:0051315 (0.02) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051276 (0.02) ! chromosome organization; GO:0050776 (0.02) ! regulation of immune response; GO:0048739 (0.02) ! cardiac muscle fiber development; GO:0048589 (0.02) ! developmental growth; GO:0045893 (0.02) ! positive regulation of transcription, DNA-templated; GO:0045892 (0.02) ! negative regulation of transcription, DNA-templated; GO:0045786 (0.02) ! negative regulation of cell cycle; GO:0045087 (0.02) ! innate immune response; GO:0044723 (0.02) ! single-organism carbohydrate metabolic process; GO:0044708 (0.02) ! single-organism behavior; GO:0043547 (0.02) ! positive regulation of GTPase activity; GO:0042981 (0.02) ! regulation of apoptotic process; GO:0042127 (0.02) ! regulation of cell proliferation; GO:0035372 (0.02) ! protein localization to microtubule; GO:0034501 (0.02) ! protein localization to kinetochore; GO:0031399 (0.02) ! regulation of protein modification process; GO:0031338 (0.02) ! regulation of vesicle fusion; GO:0031134 (0.02) ! sister chromatid biorientation; GO:0030241 (0.02) ! skeletal muscle myosin thick filament assembly; GO:0030240 (0.02) ! skeletal muscle thin filament assembly; GO:0030155 (0.02) ! regulation of cell adhesion; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0019220 (0.02) ! regulation of phosphate metabolic process; GO:0016049 (0.02) ! cell growth; GO:0010817 (0.02) ! regulation of hormone levels; GO:0010638 (0.02) ! positive regulation of organelle organization; GO:0010045 (0.02) ! response to nickel cation; GO:0010033 (0.02) ! response to organic substance; GO:0009968 (0.02) ! negative regulation of signal transduction; GO:0009967 (0.02) ! positive regulation of signal transduction; GO:0009314 (0.02) ! response to radiation; GO:0007626 (0.02) ! locomotory behavior; GO:0007600 (0.02) ! sensory perception; GO:0007519 (0.02) ! skeletal muscle tissue development; GO:0007389 (0.02) ! pattern specification process; GO:0007346 (0.02) ! regulation of mitotic cell cycle; GO:0007186 (0.02) ! G-protein coupled receptor signaling pathway; GO:0007155 (0.02) ! cell adhesion; GO:0007018 (0.02) ! microtubule-based movement; GO:0006941 (0.02) ! striated muscle contraction; GO:0006887 (0.02) ! exocytosis; GO:0006874 (0.02) ! cellular calcium ion homeostasis; GO:0006468 (0.02) ! protein phosphorylation; GO:0006325 (0.02) ! chromatin organization; GO:0006310 (0.02) ! DNA recombination; GO:2000241 (0.01) ! regulation of reproductive process; GO:2000045 (0.01) ! regulation of G1/S transition of mitotic cell cycle; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1902476 (0.01) ! chloride transmembrane transport; GO:1901991 (0.01) ! negative regulation of mitotic cell cycle phase transition; GO:1901700 (0.01) ! response to oxygen-containing compound; GO:1901575 (0.01) ! organic substance catabolic process; GO:1901564 (0.01) ! organonitrogen compound metabolic process; GO:0090630 (0.01) ! activation of GTPase activity; GO:0090307 (0.01) ! mitotic spindle assembly; GO:0090090 (0.01) ! negative regulation of canonical Wnt signaling pathway; GO:0090068 (0.01) ! positive regulation of cell cycle process; GO:0086091 (0.01) ! regulation of heart rate by cardiac conduction; GO:0086070 (0.01) ! SA node cell to atrial cardiac muscle cell communication; GO:0086015 (0.01) ! SA node cell action potential; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0072205 (0.01) ! metanephric collecting duct development; GO:0071896 (0.01) ! protein localization to adherens junction; GO:0071495 (0.01) ! cellular response to endogenous stimulus; GO:0071396 (0.01) ! cellular response to lipid; GO:0071214 (0.01) ! cellular response to abiotic stimulus; GO:0070588 (0.01) ! calcium ion transmembrane transport; GO:0061564 (0.01) ! axon development; GO:0061077 (0.01) ! chaperone-mediated protein folding; GO:0060968 (0.01) ! regulation of gene silencing; GO:0060441 (0.01) ! epithelial tube branching involved in lung morphogenesis; GO:0060429 (0.01) ! epithelium development; GO:0060361 (0.01) ! flight; GO:0060271 (0.01) ! cilium morphogenesis; GO:0060052 (0.01) ! neurofilament cytoskeleton organization; GO:0060047 (0.01) ! heart contraction; GO:0055114 (0.01) ! oxidation-reduction process; GO:0051924 (0.01) ! regulation of calcium ion transport; GO:0051646 (0.01) ! mitochondrion localization; GO:0051643 (0.01) ! endoplasmic reticulum localization; GO:0051601 (0.01) ! exocyst localization; GO:0051597 (0.01) ! response to methylmercury; GO:0051415 (0.01) ! interphase microtubule nucleation by interphase microtubule organizing center; GO:0051298 (0.01) ! centrosome duplication; GO:0051292 (0.01) ! nuclear pore complex assembly; GO:0051241 (0.01) ! negative regulation of multicellular organismal process; GO:0051093 (0.01) ! negative regulation of developmental process; GO:0051051 (0.01) ! negative regulation of transport; GO:0050982 (0.01) ! detection of mechanical stimulus; GO:0050808 (0.01) ! synapse organization; GO:0050796 (0.01) ! regulation of insulin secretion; GO:0048738 (0.01) ! cardiac muscle tissue development; GO:0048675 (0.01) ! axon extension; GO:0048666 (0.01) ! neuron development; GO:0048598 (0.01) ! embryonic morphogenesis; GO:0048488 (0.01) ! synaptic vesicle endocytosis; GO:0046928 (0.01) ! regulation of neurotransmitter secretion; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046649 (0.01) ! lymphocyte activation; GO:0046579 (0.01) ! positive regulation of Ras protein signal transduction; GO:0046488 (0.01) ! phosphatidylinositol metabolic process; GO:0046474 (0.01) ! glycerophospholipid biosynthetic process; GO:0045995 (0.01) ! regulation of embryonic development; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045936 (0.01) ! negative regulation of phosphate metabolic process; GO:0045859 (0.01) ! regulation of protein kinase activity; GO:0045596 (0.01) ! negative regulation of cell differentiation; GO:0045197 (0.01) ! establishment or maintenance of epithelial cell apical/basal polarity; GO:0045186 (0.01) ! zonula adherens assembly; GO:0045176 (0.01) ! apical protein localization; GO:0045110 (0.01) ! intermediate filament bundle assembly; GO:0045088 (0.01) ! regulation of innate immune response; GO:0044774 (0.01) ! mitotic DNA integrity checkpoint; GO:0044262 (0.01) ! cellular carbohydrate metabolic process; GO:0043313 (0.01) ! regulation of neutrophil degranulation; GO:0043254 (0.01) ! regulation of protein complex assembly; GO:0043122 (0.01) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043086 (0.01) ! negative regulation of catalytic activity; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0042742 (0.01) ! defense response to bacterium; GO:0042594 (0.01) ! response to starvation; GO:0042330 (0.01) ! taxis; GO:0042048 (0.01) ! olfactory behavior; GO:0040023 (0.01) ! establishment of nucleus localization; GO:0035545 (0.01) ! determination of left/right asymmetry in nervous system; GO:0035385 (0.01) ! Roundabout signaling pathway; GO:0035264 (0.01) ! multicellular organism growth; GO:0035150 (0.01) ! regulation of tube size; GO:0035107 (0.01) ! appendage morphogenesis; GO:0035036 (0.01) ! sperm-egg recognition; GO:0034651 (0.01) ! cortisol biosynthetic process; GO:0034453 (0.01) ! microtubule anchoring; GO:0034088 (0.01) ! maintenance of mitotic sister chromatid cohesion; GO:0033227 (0.01) ! dsRNA transport; GO:0032342 (0.01) ! aldosterone biosynthetic process; GO:0032101 (0.01) ! regulation of response to external stimulus; GO:0031647 (0.01) ! regulation of protein stability; GO:0031400 (0.01) ! negative regulation of protein modification process; GO:0031122 (0.01) ! cytoplasmic microtubule organization; GO:0031098 (0.01) ! stress-activated protein kinase signaling cascade; GO:0031058 (0.01) ! positive regulation of histone modification; GO:0030913 (0.01) ! paranodal junction assembly; GO:0030901 (0.01) ! midbrain development; GO:0030859 (0.01) ! polarized epithelial cell differentiation; GO:0030705 (0.01) ! cytoskeleton-dependent intracellular transport; GO:0030534 (0.01) ! adult behavior; GO:0030518 (0.01) ! intracellular steroid hormone receptor signaling pathway; GO:0030512 (0.01) ! negative regulation of transforming growth factor beta receptor signaling pathway; GO:0030334 (0.01) ! regulation of cell migration; GO:0030317 (0.01) ! sperm motility; GO:0030048 (0.01) ! actin filament-based movement; GO:0030042 (0.01) ! actin filament depolymerization; GO:0030031 (0.01) ! cell projection assembly; GO:0030010 (0.01) ! establishment of cell polarity; GO:0030004 (0.01) ! cellular monovalent inorganic cation homeostasis; GO:0022618 (0.01) ! ribonucleoprotein complex assembly; GO:0022008 (0.01) ! neurogenesis; GO:0019932 (0.01) ! second-messenger-mediated signaling; GO:0019233 (0.01) ! sensory perception of pain; GO:0018205 (0.01) ! peptidyl-lysine modification; GO:0018105 (0.01) ! peptidyl-serine phosphorylation; GO:0016571 (0.01) ! histone methylation; GO:0016337 (0.01) ! single organismal cell-cell adhesion; GO:0016311 (0.01) ! dephosphorylation; GO:0016266 (0.01) ! O-glycan processing; GO:0016197 (0.01) ! endosomal transport; GO:0016079 (0.01) ! synaptic vesicle exocytosis; GO:0016032 (0.01) ! viral process; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0010811 (0.01) ! positive regulation of cell-substrate adhesion; GO:0010631 (0.01) ! epithelial cell migration; GO:0010212 (0.01) ! response to ionizing radiation; GO:0009725 (0.01) ! response to hormone; GO:0009416 (0.01) ! response to light stimulus; GO:0009408 (0.01) ! response to heat; GO:0008360 (0.01) ! regulation of cell shape; GO:0008335 (0.01) ! female germline ring canal stabilization; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008064 (0.01) ! regulation of actin polymerization or depolymerization; GO:0007612 (0.01) ! learning; GO:0007605 (0.01) ! sensory perception of sound; GO:0007523 (0.01) ! larval visceral muscle development; GO:0007498 (0.01) ! mesoderm development; GO:0007420 (0.01) ! brain development; GO:0007399 (0.01) ! nervous system development; GO:0007303 (0.01) ! cytoplasmic transport, nurse cell to oocyte; GO:0007292 (0.01) ! female gamete generation; GO:0007283 (0.01) ! spermatogenesis; GO:0007265 (0.01) ! Ras protein signal transduction; GO:0007229 (0.01) ! integrin-mediated signaling pathway; GO:0007214 (0.01) ! gamma-aminobutyric acid signaling pathway; GO:0007204 (0.01) ! positive regulation of cytosolic calcium ion concentration; GO:0007162 (0.01) ! negative regulation of cell adhesion; GO:0007126 (0.01) ! meiotic nuclear division; GO:0007076 (0.01) ! mitotic chromosome condensation; GO:0007052 (0.01) ! mitotic spindle organization; GO:0007050 (0.01) ! cell cycle arrest; GO:0007009 (0.01) ! plasma membrane organization; GO:0006914 (0.01) ! autophagy; GO:0006893 (0.01) ! Golgi to plasma membrane transport; GO:0006836 (0.01) ! neurotransmitter transport; GO:0006508 (0.01) ! proteolysis; GO:0006336 (0.01) ! DNA replication-independent nucleosome assembly; GO:0006312 (0.01) ! mitotic recombination; GO:0006275 (0.01) ! regulation of DNA replication; GO:0006268 (0.01) ! DNA unwinding involved in DNA replication; GO:0006265 (0.01) ! DNA topological change; GO:0006260 (0.01) ! DNA replication; GO:0003007 (0.01) ! heart morphogenesis; GO:0003006 (0.01) ! developmental process involved in reproduction; GO:0003002 (0.01) ! regionalization; GO:0002831 (0.01) ! regulation of response to biotic stimulus; GO:0001822 (0.01) ! kidney development; GO:0001701 (0.01) ! in utero embryonic development; GO:0000910 (0.01) ! cytokinesis; GO:0000902 (0.01) ! cell morphogenesis; GO:0000819 (0.01) ! sister chromatid segregation; GO:0000724 (0.01) ! double-strand break repair via homologous recombination; GO:0000712 (0.01) ! resolution of meiotic recombination intermediates; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter GO:0044464 (0.97) ! cell part; GO:0044424 (0.95) ! intracellular part; GO:0032991 (0.69) ! macromolecular complex; GO:0043234 (0.68) ! protein complex; GO:0044444 (0.60) ! cytoplasmic part; GO:0043226 (0.57) ! organelle; GO:0043229 (0.56) ! intracellular organelle; GO:0044422 (0.47) ! organelle part; GO:0044446 (0.45) ! intracellular organelle part; GO:0005737 (0.41) ! cytoplasm; GO:0043227 (0.40) ! membrane-bounded organelle; GO:0043231 (0.38) ! intracellular membrane-bounded organelle; GO:1990234 (0.34) ! transferase complex; GO:0043232 (0.33) ! intracellular non-membrane-bounded organelle; GO:0016020 (0.33) ! membrane; GO:0044428 (0.27) ! nuclear part; GO:0005829 (0.27) ! cytosol; GO:0061695 (0.26) ! transferase complex, transferring phosphorus-containing groups; GO:0005886 (0.22) ! plasma membrane; GO:0005634 (0.22) ! nucleus; GO:0044451 (0.20) ! nucleoplasm part; GO:0005665 (0.17) ! DNA-directed RNA polymerase II, core complex; GO:0044445 (0.16) ! cytosolic part; GO:0044425 (0.14) ! membrane part; GO:0044430 (0.13) ! cytoskeletal part; GO:0005654 (0.12) ! nucleoplasm; GO:0044459 (0.11) ! plasma membrane part; GO:0044427 (0.11) ! chromosomal part; GO:0030529 (0.10) ! intracellular ribonucleoprotein complex; GO:0070013 (0.09) ! intracellular organelle lumen; GO:0019867 (0.09) ! outer membrane; GO:0005730 (0.09) ! nucleolus; GO:0005618 (0.09) ! cell wall; GO:0000790 (0.09) ! nuclear chromatin; GO:0097458 (0.08) ! neuron part; GO:0044421 (0.08) ! extracellular region part; GO:0034081 (0.08) ! polyketide synthase complex; GO:0032300 (0.08) ! mismatch repair complex; GO:0031416 (0.08) ! NatB complex; GO:0031415 (0.08) ! NatA complex; GO:0022626 (0.08) ! cytosolic ribosome; GO:0009360 (0.08) ! DNA polymerase III complex; GO:0005835 (0.08) ! fatty acid synthase complex; GO:0005811 (0.08) ! lipid particle; GO:0005777 (0.08) ! peroxisome; GO:0005759 (0.08) ! mitochondrial matrix; GO:0005739 (0.08) ! mitochondrion; GO:0005719 (0.08) ! nuclear euchromatin; GO:0000974 (0.08) ! Prp19 complex; GO:0042995 (0.07) ! cell projection; GO:0016021 (0.07) ! integral component of membrane; GO:0005887 (0.06) ! integral component of plasma membrane; GO:0099513 (0.05) ! polymeric cytoskeletal fiber; GO:0098796 (0.05) ! membrane protein complex; GO:0044449 (0.05) ! contractile fiber part; GO:0030054 (0.05) ! cell junction; GO:0005856 (0.05) ! cytoskeleton; GO:0098797 (0.04) ! plasma membrane protein complex; GO:0044463 (0.04) ! cell projection part; GO:0031988 (0.04) ! membrane-bounded vesicle; GO:0031012 (0.04) ! extracellular matrix; GO:0030018 (0.04) ! Z disc; GO:0005912 (0.04) ! adherens junction; GO:0005874 (0.04) ! microtubule; GO:0098858 (0.03) ! actin-based cell projection; GO:0070062 (0.03) ! extracellular exosome; GO:0043005 (0.03) ! neuron projection; GO:0035371 (0.03) ! microtubule plus-end; GO:0034703 (0.03) ! cation channel complex; GO:0033267 (0.03) ! axon part; GO:0031430 (0.03) ! M band; GO:0030426 (0.03) ! growth cone; GO:0005924 (0.03) ! cell-substrate adherens junction; GO:0005875 (0.03) ! microtubule associated complex; GO:0005694 (0.03) ! chromosome; GO:0000235 (0.03) ! astral microtubule; GO:0098590 (0.02) ! plasma membrane region; GO:0048471 (0.02) ! perinuclear region of cytoplasm; GO:0045169 (0.02) ! fusome; GO:0044456 (0.02) ! synapse part; GO:0044431 (0.02) ! Golgi apparatus part; GO:0044295 (0.02) ! axonal growth cone; GO:0043235 (0.02) ! receptor complex; GO:0030175 (0.02) ! filopodium; GO:0005927 (0.02) ! muscle tendon junction; GO:0005891 (0.02) ! voltage-gated calcium channel complex; GO:0005865 (0.02) ! striated muscle thin filament; GO:0005859 (0.02) ! muscle myosin complex; GO:0005819 (0.02) ! spindle; GO:0005615 (0.02) ! extracellular space; GO:0000777 (0.02) ! condensed chromosome kinetochore; GO:0098793 (0.01) ! presynapse; GO:0097060 (0.01) ! synaptic membrane; GO:0071013 (0.01) ! catalytic step 2 spliceosome; GO:0070847 (0.01) ! core mediator complex; GO:0051233 (0.01) ! spindle midzone; GO:0045202 (0.01) ! synapse; GO:0045121 (0.01) ! membrane raft; GO:0044666 (0.01) ! MLL3/4 complex; GO:0043204 (0.01) ! perikaryon; GO:0043034 (0.01) ! costamere; GO:0043025 (0.01) ! neuronal cell body; GO:0034707 (0.01) ! chloride channel complex; GO:0031672 (0.01) ! A band; GO:0030496 (0.01) ! midbody; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030133 (0.01) ! transport vesicle; GO:0030117 (0.01) ! membrane coat; GO:0019897 (0.01) ! extrinsic component of plasma membrane; GO:0016592 (0.01) ! mediator complex; GO:0016324 (0.01) ! apical plasma membrane; GO:0016234 (0.01) ! inclusion body; GO:0015629 (0.01) ! actin cytoskeleton; GO:0014069 (0.01) ! postsynaptic density; GO:0012505 (0.01) ! endomembrane system; GO:0009986 (0.01) ! cell surface; GO:0008305 (0.01) ! integrin complex; GO:0008023 (0.01) ! transcription elongation factor complex; GO:0005938 (0.01) ! cell cortex; GO:0005925 (0.01) ! focal adhesion; GO:0005913 (0.01) ! cell-cell adherens junction; GO:0005884 (0.01) ! actin filament; GO:0005871 (0.01) ! kinesin complex; GO:0005816 (0.01) ! spindle pole body; GO:0005813 (0.01) ! centrosome; GO:0005796 (0.01) ! Golgi lumen; GO:0005794 (0.01) ! Golgi apparatus; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005773 (0.01) ! vacuole; GO:0005640 (0.01) ! nuclear outer membrane; GO:0005635 (0.01) ! nuclear envelope; GO:0005622 (0.01) ! intracellular; GO:0005578 (0.01) ! proteinaceous extracellular matrix; GO:0005576 (0.01) ! extracellular region; GO:0001726 (0.01) ! ruffle; GO:0000930 (0.01) ! gamma-tubulin complex; GO:0000923 (0.01) ! equatorial microtubule organizing center; GO:0000922 (0.01) ! spindle pole; GO:0000793 (0.01) ! condensed chromosome; GO:0000228 (0.01) ! nuclear chromosome; GO:0000145 (0.01) ! exocyst 1 58541587-58544368 (17q22) Testis: 14.73; Spleen: 0.24; Lung: 0.22; Thyroid: 0.18; Pituitary: 0.13; Breast - Mammary Tissue: 0.13; Minor Salivary Gland: 0.11; Bladder: 0.11; Prostate: 0.11; Cervix - Ectocervix: 0.11; Cervix - Endocervix: 0.09; Artery - Aorta: 0.09; Small Intestine - Terminal Ileum: 0.08; Artery - Tibial: 0.08; Liver: 0.08; Stomach: 0.07; Artery - Coronary: 0.07; Nerve - Tibial: 0.07; Colon - Transverse: 0.07; Skin - Sun Exposed (Lower leg): 0.06; Brain - Cerebellum: 0.06; Pancreas: 0.06; Kidney - Cortex: 0.05; Fallopian Tube: 0.05; Adipose - Subcutaneous: 0.05; Ovary: 0.05; Adipose - Visceral (Omentum): 0.05; Adrenal Gland: 0.05; Brain - Cerebellar Hemisphere: 0.04; Uterus: 0.04; Skin - Not Sun Exposed (Suprapubic): 0.03; Cells - Transformed fibroblasts: 0.03; Vagina: 0.03; Esophagus - Mucosa: 0.02; Heart - Atrial Appendage: 0.02; MVKTNKPGAKVAVSAQRGSEVTTNTSPQQGHGYVLASSHRSAAVSLNPSHRRSEAAHPTTPHSASDYPRSVSLQSGPGHYAVPTPRGPETGPRTESSRHSSPHLKSQKTQTLASHASSRQWKVSPPREEAARRGSESKSGREVGHHASSIPDAKSTHQLSFQDQKNNLQSQILEDDPPSKVQNPQGVRVPRRILSYPKDEAVQTEPIQRITTTSEIRSPRSPSLLEHGSSCVSADYQTAQRRVPVEESETGPYGPIPSKPKALYRNMNLDSLLKLSVLKDSDGVHRVSARVDPESLHKYSAYPETKPSAKVLVSSQVESNVRTPIRGNSEVGRRVTISPGVQSVEPTHHVTVPSVSEGSHKSSMFVTPEPIYKQQTQKPPEITYMSQGPTPRYPELSQKPSIHAELELTPRPLPPRSLPRYGPDSSWWPLLNPEVETPQSQLTTPDFEPKCSPSLDLLLSGFKIDSSPFCEDLKFQREKASLSPPSPPKEFPSWAPLSEVPQTPKHTCKQPIQRFTAFFLDVSEEMYNRVIWWLKGLCFSLLWAHCGSLGDGRTGEEWHLCIYRAGSFRR C17orf82 Putative uncharacterized protein C17orf82 CQ082_HUMAN (Q86X59-1) GO:0015926 (0.39) ! glucosidase activity; GO:0003676 (0.34) ! nucleic acid binding GO:0009987 (0.69) ! cellular process; GO:0016043 (0.55) ! cellular component organization; GO:0032502 (0.52) ! developmental process; GO:0044699 (0.49) ! single-organism process; GO:0048856 (0.48) ! anatomical structure development; GO:0051179 (0.45) ! localization; GO:0071704 (0.44) ! organic substance metabolic process; GO:0006810 (0.44) ! transport; GO:0043170 (0.43) ! macromolecule metabolic process; GO:0044238 (0.42) ! primary metabolic process; GO:0044237 (0.42) ! cellular metabolic process; GO:0043933 (0.42) ! macromolecular complex subunit organization; GO:0022607 (0.42) ! cellular component assembly; GO:0044260 (0.40) ! cellular macromolecule metabolic process; GO:0065003 (0.39) ! macromolecular complex assembly; GO:0051641 (0.39) ! cellular localization; GO:0051649 (0.38) ! establishment of localization in cell; GO:0048731 (0.38) ! system development; GO:0006139 (0.38) ! nucleobase-containing compound metabolic process; GO:0090304 (0.37) ! nucleic acid metabolic process; GO:0065007 (0.37) ! biological regulation; GO:0034622 (0.37) ! cellular macromolecular complex assembly; GO:0046907 (0.36) ! intracellular transport; GO:0044249 (0.36) ! cellular biosynthetic process; GO:0022618 (0.36) ! ribonucleoprotein complex assembly; GO:0016070 (0.36) ! RNA metabolic process; GO:0009059 (0.36) ! macromolecule biosynthetic process; GO:0044763 (0.35) ! single-organism cellular process; GO:0034654 (0.35) ! nucleobase-containing compound biosynthetic process; GO:0034645 (0.35) ! cellular macromolecule biosynthetic process; GO:0016071 (0.35) ! mRNA metabolic process; GO:0006913 (0.34) ! nucleocytoplasmic transport; GO:0006351 (0.34) ! transcription, DNA-templated; GO:0000398 (0.34) ! mRNA splicing, via spliceosome; GO:0009056 (0.33) ! catabolic process; GO:1901575 (0.31) ! organic substance catabolic process; GO:0005975 (0.31) ! carbohydrate metabolic process; GO:0051275 (0.30) ! beta-glucan catabolic process; GO:0050789 (0.30) ! regulation of biological process; GO:0030243 (0.30) ! cellulose metabolic process; GO:0050794 (0.26) ! regulation of cellular process; GO:0044767 (0.25) ! single-organism developmental process; GO:0032501 (0.16) ! multicellular organismal process; GO:0065008 (0.15) ! regulation of biological quality; GO:0050896 (0.15) ! response to stimulus; GO:0048518 (0.13) ! positive regulation of biological process; GO:0044707 (0.13) ! single-multicellular organism process; GO:0009653 (0.13) ! anatomical structure morphogenesis; GO:0048522 (0.11) ! positive regulation of cellular process; GO:0030198 (0.10) ! extracellular matrix organization; GO:0007165 (0.10) ! signal transduction; GO:0006996 (0.10) ! organelle organization; GO:0051239 (0.09) ! regulation of multicellular organismal process; GO:0048869 (0.09) ! cellular developmental process; GO:0048523 (0.09) ! negative regulation of cellular process; GO:0048513 (0.09) ! animal organ development; GO:0032879 (0.09) ! regulation of localization; GO:0051716 (0.08) ! cellular response to stimulus; GO:1902578 (0.07) ! single-organism localization; GO:0071822 (0.07) ! protein complex subunit organization; GO:0051128 (0.07) ! regulation of cellular component organization; GO:0050793 (0.07) ! regulation of developmental process; GO:0044710 (0.07) ! single-organism metabolic process; GO:0042391 (0.07) ! regulation of membrane potential; GO:0019222 (0.07) ! regulation of metabolic process; GO:0006950 (0.07) ! response to stress; GO:2000026 (0.06) ! regulation of multicellular organismal development; GO:0080090 (0.06) ! regulation of primary metabolic process; GO:0060255 (0.06) ! regulation of macromolecule metabolic process; GO:0051049 (0.06) ! regulation of transport; GO:0048583 (0.06) ! regulation of response to stimulus; GO:0045595 (0.06) ! regulation of cell differentiation; GO:0044765 (0.06) ! single-organism transport; GO:0042221 (0.06) ! response to chemical; GO:0031323 (0.06) ! regulation of cellular metabolic process; GO:0023051 (0.06) ! regulation of signaling; GO:0010646 (0.06) ! regulation of cell communication; GO:0009628 (0.06) ! response to abiotic stimulus; GO:1902589 (0.05) ! single-organism organelle organization; GO:0086010 (0.05) ! membrane depolarization during action potential; GO:0044700 (0.05) ! single organism signaling; GO:0022603 (0.05) ! regulation of anatomical structure morphogenesis; GO:0019538 (0.05) ! protein metabolic process; GO:0016192 (0.05) ! vesicle-mediated transport; GO:0010033 (0.05) ! response to organic substance; GO:0009966 (0.05) ! regulation of signal transduction; GO:0009887 (0.05) ! organ morphogenesis; GO:0009605 (0.05) ! response to external stimulus; GO:0008104 (0.05) ! protein localization; GO:0007155 (0.05) ! cell adhesion; GO:0007154 (0.05) ! cell communication; GO:0007010 (0.05) ! cytoskeleton organization; GO:0006928 (0.05) ! movement of cell or subcellular component; GO:0006811 (0.05) ! ion transport; GO:0006461 (0.05) ! protein complex assembly; GO:0003008 (0.05) ! system process; GO:1903530 (0.04) ! regulation of secretion by cell; GO:1902580 (0.04) ! single-organism cellular localization; GO:1901700 (0.04) ! response to oxygen-containing compound; GO:1901698 (0.04) ! response to nitrogen compound; GO:0071702 (0.04) ! organic substance transport; GO:0071495 (0.04) ! cellular response to endogenous stimulus; GO:0071310 (0.04) ! cellular response to organic substance; GO:0060627 (0.04) ! regulation of vesicle-mediated transport; GO:0055085 (0.04) ! transmembrane transport; GO:0051130 (0.04) ! positive regulation of cellular component organization; GO:0050877 (0.04) ! neurological system process; GO:0050767 (0.04) ! regulation of neurogenesis; GO:0048729 (0.04) ! tissue morphogenesis; GO:0048584 (0.04) ! positive regulation of response to stimulus; GO:0042592 (0.04) ! homeostatic process; GO:0040011 (0.04) ! locomotion; GO:0033554 (0.04) ! cellular response to stress; GO:0032989 (0.04) ! cellular component morphogenesis; GO:0030574 (0.04) ! collagen catabolic process; GO:0030030 (0.04) ! cell projection organization; GO:0030001 (0.04) ! metal ion transport; GO:0022604 (0.04) ! regulation of cell morphogenesis; GO:0009893 (0.04) ! positive regulation of metabolic process; GO:0009888 (0.04) ! tissue development; GO:0007267 (0.04) ! cell-cell signaling; GO:0007166 (0.04) ! cell surface receptor signaling pathway; GO:0007017 (0.04) ! microtubule-based process; GO:0006464 (0.04) ! cellular protein modification process; GO:0006355 (0.04) ! regulation of transcription, DNA-templated; GO:1902531 (0.03) ! regulation of intracellular signal transduction; GO:1901701 (0.03) ! cellular response to oxygen-containing compound; GO:1901699 (0.03) ! cellular response to nitrogen compound; GO:0071214 (0.03) ! cellular response to abiotic stimulus; GO:0065009 (0.03) ! regulation of molecular function; GO:0051704 (0.03) ! multi-organism process; GO:0051270 (0.03) ! regulation of cellular component movement; GO:0051241 (0.03) ! negative regulation of multicellular organismal process; GO:0051240 (0.03) ! positive regulation of multicellular organismal process; GO:0051050 (0.03) ! positive regulation of transport; GO:0048878 (0.03) ! chemical homeostasis; GO:0048812 (0.03) ! neuron projection morphogenesis; GO:0048646 (0.03) ! anatomical structure formation involved in morphogenesis; GO:0048598 (0.03) ! embryonic morphogenesis; GO:0044802 (0.03) ! single-organism membrane organization; GO:0044087 (0.03) ! regulation of cellular component biogenesis; GO:0040008 (0.03) ! regulation of growth; GO:0035556 (0.03) ! intracellular signal transduction; GO:0034613 (0.03) ! cellular protein localization; GO:0034220 (0.03) ! ion transmembrane transport; GO:0033043 (0.03) ! regulation of organelle organization; GO:0032940 (0.03) ! secretion by cell; GO:0031325 (0.03) ! positive regulation of cellular metabolic process; GO:0031324 (0.03) ! negative regulation of cellular metabolic process; GO:0030199 (0.03) ! collagen fibril organization; GO:0030155 (0.03) ! regulation of cell adhesion; GO:0030154 (0.03) ! cell differentiation; GO:0030036 (0.03) ! actin cytoskeleton organization; GO:0022414 (0.03) ! reproductive process; GO:0017158 (0.03) ! regulation of calcium ion-dependent exocytosis; GO:0015031 (0.03) ! protein transport; GO:0010975 (0.03) ! regulation of neuron projection development; GO:0010769 (0.03) ! regulation of cell morphogenesis involved in differentiation; GO:0010720 (0.03) ! positive regulation of cell development; GO:0010628 (0.03) ! positive regulation of gene expression; GO:0010243 (0.03) ! response to organonitrogen compound; GO:0009967 (0.03) ! positive regulation of signal transduction; GO:0009612 (0.03) ! response to mechanical stimulus; GO:0009314 (0.03) ! response to radiation; GO:0007610 (0.03) ! behavior; GO:0007275 (0.03) ! multicellular organism development; GO:0007268 (0.03) ! chemical synaptic transmission; GO:0007167 (0.03) ! enzyme linked receptor protein signaling pathway; GO:0006979 (0.03) ! response to oxidative stress; GO:0006816 (0.03) ! calcium ion transport; GO:0002682 (0.03) ! regulation of immune system process; GO:0001501 (0.03) ! skeletal system development; GO:0000226 (0.03) ! microtubule cytoskeleton organization; GO:1903532 (0.02) ! positive regulation of secretion by cell; GO:1903047 (0.02) ! mitotic cell cycle process; GO:1902582 (0.02) ! single-organism intracellular transport; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:0099643 (0.02) ! signal release from synapse; GO:0099531 (0.02) ! presynaptic process involved in chemical synaptic transmission; GO:0099003 (0.02) ! vesicle mediated transport in synapse; GO:0090501 (0.02) ! RNA phosphodiester bond hydrolysis; GO:0080134 (0.02) ! regulation of response to stress; GO:0071470 (0.02) ! cellular response to osmotic stress; GO:0071230 (0.02) ! cellular response to amino acid stimulus; GO:0070925 (0.02) ! organelle assembly; GO:0061061 (0.02) ! muscle structure development; GO:0051707 (0.02) ! response to other organism; GO:0051606 (0.02) ! detection of stimulus; GO:0051491 (0.02) ! positive regulation of filopodium assembly; GO:0051336 (0.02) ! regulation of hydrolase activity; GO:0051259 (0.02) ! protein oligomerization; GO:0051093 (0.02) ! negative regulation of developmental process; GO:0050808 (0.02) ! synapse organization; GO:0050776 (0.02) ! regulation of immune response; GO:0048813 (0.02) ! dendrite morphogenesis; GO:0048589 (0.02) ! developmental growth; GO:0048585 (0.02) ! negative regulation of response to stimulus; GO:0048489 (0.02) ! synaptic vesicle transport; GO:0048468 (0.02) ! cell development; GO:0048193 (0.02) ! Golgi vesicle transport; GO:0045893 (0.02) ! positive regulation of transcription, DNA-templated; GO:0045892 (0.02) ! negative regulation of transcription, DNA-templated; GO:0045773 (0.02) ! positive regulation of axon extension; GO:0045596 (0.02) ! negative regulation of cell differentiation; GO:0044711 (0.02) ! single-organism biosynthetic process; GO:0044708 (0.02) ! single-organism behavior; GO:0044702 (0.02) ! single organism reproductive process; GO:0044281 (0.02) ! small molecule metabolic process; GO:0044093 (0.02) ! positive regulation of molecular function; GO:0044057 (0.02) ! regulation of system process; GO:0042981 (0.02) ! regulation of apoptotic process; GO:0035149 (0.02) ! lumen formation, open tracheal system; GO:0035147 (0.02) ! branch fusion, open tracheal system; GO:0035107 (0.02) ! appendage morphogenesis; GO:0033365 (0.02) ! protein localization to organelle; GO:0032836 (0.02) ! glomerular basement membrane development; GO:0030716 (0.02) ! oocyte fate determination; GO:0030518 (0.02) ! intracellular steroid hormone receptor signaling pathway; GO:0030334 (0.02) ! regulation of cell migration; GO:0023057 (0.02) ! negative regulation of signaling; GO:0016477 (0.02) ! cell migration; GO:0016337 (0.02) ! single organismal cell-cell adhesion; GO:0016319 (0.02) ! mushroom body development; GO:0016204 (0.02) ! determination of muscle attachment site; GO:0016203 (0.02) ! muscle attachment; GO:0016199 (0.02) ! axon midline choice point recognition; GO:0016050 (0.02) ! vesicle organization; GO:0014070 (0.02) ! response to organic cyclic compound; GO:0010648 (0.02) ! negative regulation of cell communication; GO:0009792 (0.02) ! embryo development ending in birth or egg hatching; GO:0009650 (0.02) ! UV protection; GO:0007605 (0.02) ! sensory perception of sound; GO:0007475 (0.02) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.02) ! open tracheal system development; GO:0007423 (0.02) ! sensory organ development; GO:0007409 (0.02) ! axonogenesis; GO:0007169 (0.02) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007026 (0.02) ! negative regulation of microtubule depolymerization; GO:0006898 (0.02) ! receptor-mediated endocytosis; GO:0006887 (0.02) ! exocytosis; GO:0006886 (0.02) ! intracellular protein transport; GO:0006875 (0.02) ! cellular metal ion homeostasis; GO:0006796 (0.02) ! phosphate-containing compound metabolic process; GO:0006357 (0.02) ! regulation of transcription from RNA polymerase II promoter; GO:0006325 (0.02) ! chromatin organization; GO:0006259 (0.02) ! DNA metabolic process; GO:0002376 (0.02) ! immune system process; GO:0002009 (0.02) ! morphogenesis of an epithelium; GO:0001932 (0.02) ! regulation of protein phosphorylation; GO:0001578 (0.02) ! microtubule bundle formation; GO:0001503 (0.02) ! ossification; GO:0000245 (0.02) ! spliceosomal complex assembly; GO:2001223 (0.01) ! negative regulation of neuron migration; GO:2000047 (0.01) ! regulation of cell-cell adhesion mediated by cadherin; GO:1903225 (0.01) ! negative regulation of endodermal cell differentiation; GO:1903046 (0.01) ! meiotic cell cycle process; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1901991 (0.01) ! negative regulation of mitotic cell cycle phase transition; GO:1901615 (0.01) ! organic hydroxy compound metabolic process; GO:1901564 (0.01) ! organonitrogen compound metabolic process; GO:1901135 (0.01) ! carbohydrate derivative metabolic process; GO:0098910 (0.01) ! regulation of atrial cardiac muscle cell action potential; GO:0098662 (0.01) ! inorganic cation transmembrane transport; GO:0090276 (0.01) ! regulation of peptide hormone secretion; GO:0090114 (0.01) ! COPII-coated vesicle budding; GO:0090110 (0.01) ! cargo loading into COPII-coated vesicle; GO:0090066 (0.01) ! regulation of anatomical structure size; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0072661 (0.01) ! protein targeting to plasma membrane; GO:0071711 (0.01) ! basement membrane organization; GO:0071705 (0.01) ! nitrogen compound transport; GO:0071407 (0.01) ! cellular response to organic cyclic compound; GO:0071396 (0.01) ! cellular response to lipid; GO:0071363 (0.01) ! cellular response to growth factor stimulus; GO:0070509 (0.01) ! calcium ion import; GO:0070482 (0.01) ! response to oxygen levels; GO:0070372 (0.01) ! regulation of ERK1 and ERK2 cascade; GO:0070208 (0.01) ! protein heterotrimerization; GO:0061448 (0.01) ! connective tissue development; GO:0061333 (0.01) ! renal tubule morphogenesis; GO:0060536 (0.01) ! cartilage morphogenesis; GO:0060429 (0.01) ! epithelium development; GO:0060415 (0.01) ! muscle tissue morphogenesis; GO:0060351 (0.01) ! cartilage development involved in endochondral bone morphogenesis; GO:0060271 (0.01) ! cilium morphogenesis; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0060021 (0.01) ! palate development; GO:0055113 (0.01) ! epiboly involved in gastrulation with mouth forming second; GO:0051591 (0.01) ! response to cAMP; GO:0051315 (0.01) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051297 (0.01) ! centrosome organization; GO:0051260 (0.01) ! protein homooligomerization; GO:0051222 (0.01) ! positive regulation of protein transport; GO:0050982 (0.01) ! detection of mechanical stimulus; GO:0050906 (0.01) ! detection of stimulus involved in sensory perception; GO:0050878 (0.01) ! regulation of body fluid levels; GO:0050829 (0.01) ! defense response to Gram-negative bacterium; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0050792 (0.01) ! regulation of viral process; GO:0050708 (0.01) ! regulation of protein secretion; GO:0048791 (0.01) ! calcium ion-regulated exocytosis of neurotransmitter; GO:0048747 (0.01) ! muscle fiber development; GO:0048705 (0.01) ! skeletal system morphogenesis; GO:0048675 (0.01) ! axon extension; GO:0048666 (0.01) ! neuron development; GO:0048592 (0.01) ! eye morphogenesis; GO:0048570 (0.01) ! notochord morphogenesis; GO:0048545 (0.01) ! response to steroid hormone; GO:0048514 (0.01) ! blood vessel morphogenesis; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046740 (0.01) ! transport of virus in host, cell to cell; GO:0046649 (0.01) ! lymphocyte activation; GO:0046488 (0.01) ! phosphatidylinositol metabolic process; GO:0045956 (0.01) ! positive regulation of calcium ion-dependent exocytosis; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045936 (0.01) ! negative regulation of phosphate metabolic process; GO:0045926 (0.01) ! negative regulation of growth; GO:0045214 (0.01) ! sarcomere organization; GO:0045089 (0.01) ! positive regulation of innate immune response; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0043902 (0.01) ! positive regulation of multi-organism process; GO:0043589 (0.01) ! skin morphogenesis; GO:0043588 (0.01) ! skin development; GO:0043547 (0.01) ! positive regulation of GTPase activity; GO:0043410 (0.01) ! positive regulation of MAPK cascade; GO:0043269 (0.01) ! regulation of ion transport; GO:0043206 (0.01) ! extracellular fibril organization; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0042953 (0.01) ! lipoprotein transport; GO:0042787 (0.01) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0042335 (0.01) ! cuticle development; GO:0042330 (0.01) ! taxis; GO:0042060 (0.01) ! wound healing; GO:0038063 (0.01) ! collagen-activated tyrosine kinase receptor signaling pathway; GO:0035987 (0.01) ! endodermal cell differentiation; GO:0035372 (0.01) ! protein localization to microtubule; GO:0035295 (0.01) ! tube development; GO:0035094 (0.01) ! response to nicotine; GO:0035088 (0.01) ! establishment or maintenance of apical/basal cell polarity; GO:0035025 (0.01) ! positive regulation of Rho protein signal transduction; GO:0034504 (0.01) ! protein localization to nucleus; GO:0034501 (0.01) ! protein localization to kinetochore; GO:0034097 (0.01) ! response to cytokine; GO:0033339 (0.01) ! pectoral fin development; GO:0033334 (0.01) ! fin morphogenesis; GO:0032964 (0.01) ! collagen biosynthetic process; GO:0032870 (0.01) ! cellular response to hormone stimulus; GO:0032844 (0.01) ! regulation of homeostatic process; GO:0032526 (0.01) ! response to retinoic acid; GO:0032386 (0.01) ! regulation of intracellular transport; GO:0031581 (0.01) ! hemidesmosome assembly; GO:0031214 (0.01) ! biomineral tissue development; GO:0031175 (0.01) ! neuron projection development; GO:0031134 (0.01) ! sister chromatid biorientation; GO:0031101 (0.01) ! fin regeneration; GO:0030903 (0.01) ! notochord development; GO:0030705 (0.01) ! cytoskeleton-dependent intracellular transport; GO:0030534 (0.01) ! adult behavior; GO:0030335 (0.01) ! positive regulation of cell migration; GO:0030278 (0.01) ! regulation of ossification; GO:0030168 (0.01) ! platelet activation; GO:0030111 (0.01) ! regulation of Wnt signaling pathway; GO:0030031 (0.01) ! cell projection assembly; GO:0022412 (0.01) ! cellular process involved in reproduction in multicellular organism; GO:0022411 (0.01) ! cellular component disassembly; GO:0022008 (0.01) ! neurogenesis; GO:0021987 (0.01) ! cerebral cortex development; GO:0019932 (0.01) ! second-messenger-mediated signaling; GO:0019233 (0.01) ! sensory perception of pain; GO:0018193 (0.01) ! peptidyl-amino acid modification; GO:0016570 (0.01) ! histone modification; GO:0016525 (0.01) ! negative regulation of angiogenesis; GO:0016338 (0.01) ! calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; GO:0010927 (0.01) ! cellular component assembly involved in morphogenesis; GO:0010810 (0.01) ! regulation of cell-substrate adhesion; GO:0010638 (0.01) ! positive regulation of organelle organization; GO:0010038 (0.01) ! response to metal ion; GO:0009615 (0.01) ! response to virus; GO:0008610 (0.01) ! lipid biosynthetic process; GO:0008544 (0.01) ! epidermis development; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008219 (0.01) ! cell death; GO:0008217 (0.01) ! regulation of blood pressure; GO:0008045 (0.01) ! motor neuron axon guidance; GO:0007638 (0.01) ! mechanosensory behavior; GO:0007626 (0.01) ! locomotory behavior; GO:0007612 (0.01) ! learning; GO:0007601 (0.01) ! visual perception; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007517 (0.01) ! muscle organ development; GO:0007507 (0.01) ! heart development; GO:0007420 (0.01) ! brain development; GO:0007417 (0.01) ! central nervous system development; GO:0007416 (0.01) ! synapse assembly; GO:0007283 (0.01) ! spermatogenesis; GO:0007274 (0.01) ! neuromuscular synaptic transmission; GO:0007271 (0.01) ! synaptic transmission, cholinergic; GO:0007269 (0.01) ! neurotransmitter secretion; GO:0007265 (0.01) ! Ras protein signal transduction; GO:0007229 (0.01) ! integrin-mediated signaling pathway; GO:0007204 (0.01) ! positive regulation of cytosolic calcium ion concentration; GO:0007187 (0.01) ! G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; GO:0007179 (0.01) ! transforming growth factor beta receptor signaling pathway; GO:0007162 (0.01) ! negative regulation of cell adhesion; GO:0007160 (0.01) ! cell-matrix adhesion; GO:0007156 (0.01) ! homophilic cell adhesion via plasma membrane adhesion molecules; GO:0007018 (0.01) ! microtubule-based movement; GO:0007005 (0.01) ! mitochondrion organization; GO:0006936 (0.01) ! muscle contraction; GO:0006906 (0.01) ! vesicle fusion; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006821 (0.01) ! chloride transport; GO:0006508 (0.01) ! proteolysis; GO:0006379 (0.01) ! mRNA cleavage; GO:0006366 (0.01) ! transcription from RNA polymerase II promoter; GO:0006334 (0.01) ! nucleosome assembly; GO:0006281 (0.01) ! DNA repair; GO:0006082 (0.01) ! organic acid metabolic process; GO:0003007 (0.01) ! heart morphogenesis; GO:0003006 (0.01) ! developmental process involved in reproduction; GO:0003002 (0.01) ! regionalization; GO:0002683 (0.01) ! negative regulation of immune system process; GO:0002062 (0.01) ! chondrocyte differentiation; GO:0001958 (0.01) ! endochondral ossification; GO:0001894 (0.01) ! tissue homeostasis; GO:0001763 (0.01) ! morphogenesis of a branching structure; GO:0001732 (0.01) ! formation of cytoplasmic translation initiation complex; GO:0001701 (0.01) ! in utero embryonic development; GO:0001568 (0.01) ! blood vessel development; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter; GO:0000045 (0.01) ! autophagosome assembly; GO:0000041 (0.01) ! transition metal ion transport GO:0044464 (0.80) ! cell part; GO:0044424 (0.65) ! intracellular part; GO:0005576 (0.53) ! extracellular region; GO:0016020 (0.48) ! membrane; GO:0005737 (0.44) ! cytoplasm; GO:0032991 (0.41) ! macromolecular complex; GO:0044444 (0.40) ! cytoplasmic part; GO:0043234 (0.39) ! protein complex; GO:0044422 (0.38) ! organelle part; GO:0044446 (0.36) ! intracellular organelle part; GO:0005886 (0.33) ! plasma membrane; GO:0043226 (0.31) ! organelle; GO:0043229 (0.27) ! intracellular organelle; GO:0043227 (0.27) ! membrane-bounded organelle; GO:0005829 (0.27) ! cytosol; GO:0044428 (0.23) ! nuclear part; GO:0043231 (0.23) ! intracellular membrane-bounded organelle; GO:0005618 (0.23) ! cell wall; GO:0044425 (0.22) ! membrane part; GO:0044421 (0.18) ! extracellular region part; GO:0043232 (0.17) ! intracellular non-membrane-bounded organelle; GO:0005634 (0.17) ! nucleus; GO:0097458 (0.16) ! neuron part; GO:0044451 (0.16) ! nucleoplasm part; GO:0042995 (0.16) ! cell projection; GO:0016021 (0.16) ! integral component of membrane; GO:0005654 (0.15) ! nucleoplasm; GO:0043005 (0.14) ! neuron projection; GO:0030529 (0.14) ! intracellular ribonucleoprotein complex; GO:0030018 (0.12) ! Z disc; GO:0005622 (0.12) ! intracellular; GO:0005581 (0.12) ! collagen trimer; GO:0097504 (0.11) ! Gemini of coiled bodies; GO:0043204 (0.11) ! perikaryon; GO:0036464 (0.11) ! cytoplasmic ribonucleoprotein granule; GO:0034719 (0.11) ! SMN-Sm protein complex; GO:0032797 (0.11) ! SMN complex; GO:0015030 (0.11) ! Cajal body; GO:0044420 (0.09) ! extracellular matrix component; GO:0031012 (0.09) ! extracellular matrix; GO:0044459 (0.08) ! plasma membrane part; GO:0031988 (0.08) ! membrane-bounded vesicle; GO:0044432 (0.07) ! endoplasmic reticulum part; GO:0044430 (0.07) ! cytoskeletal part; GO:0098796 (0.05) ! membrane protein complex; GO:0070062 (0.05) ! extracellular exosome; GO:0005788 (0.05) ! endoplasmic reticulum lumen; GO:0005615 (0.05) ! extracellular space; GO:0044463 (0.04) ! cell projection part; GO:0030054 (0.04) ! cell junction; GO:0005887 (0.04) ! integral component of plasma membrane; GO:0005587 (0.04) ! collagen type IV trimer; GO:0005583 (0.04) ! fibrillar collagen trimer; GO:0005578 (0.04) ! proteinaceous extracellular matrix; GO:1902494 (0.03) ! catalytic complex; GO:0099513 (0.03) ! polymeric cytoskeletal fiber; GO:0098797 (0.03) ! plasma membrane protein complex; GO:0071013 (0.03) ! catalytic step 2 spliceosome; GO:0044456 (0.03) ! synapse part; GO:0031410 (0.03) ! cytoplasmic vesicle; GO:0031090 (0.03) ! organelle membrane; GO:0030055 (0.03) ! cell-substrate junction; GO:0005856 (0.03) ! cytoskeleton; GO:0005684 (0.03) ! U2-type spliceosomal complex; GO:0005604 (0.03) ! basement membrane; GO:1990234 (0.02) ! transferase complex; GO:0098858 (0.02) ! actin-based cell projection; GO:0098805 (0.02) ! whole membrane; GO:0098590 (0.02) ! plasma membrane region; GO:0098588 (0.02) ! bounding membrane of organelle; GO:0071944 (0.02) ! cell periphery; GO:0071004 (0.02) ! U2-type prespliceosome; GO:0070847 (0.02) ! core mediator complex; GO:0045202 (0.02) ! synapse; GO:0044433 (0.02) ! cytoplasmic vesicle part; GO:0044427 (0.02) ! chromosomal part; GO:0035371 (0.02) ! microtubule plus-end; GO:0034703 (0.02) ! cation channel complex; GO:0033267 (0.02) ! axon part; GO:0030426 (0.02) ! growth cone; GO:0030133 (0.02) ! transport vesicle; GO:0030117 (0.02) ! membrane coat; GO:0016592 (0.02) ! mediator complex; GO:0009986 (0.02) ! cell surface; GO:0005924 (0.02) ! cell-substrate adherens junction; GO:0005783 (0.02) ! endoplasmic reticulum; GO:0005689 (0.02) ! U12-type spliceosomal complex; GO:0005686 (0.02) ! U2 snRNP; GO:0005588 (0.02) ! collagen type V trimer; GO:0000235 (0.02) ! astral microtubule; GO:0098793 (0.01) ! presynapse; GO:0098791 (0.01) ! Golgi subcompartment; GO:0098589 (0.01) ! membrane region; GO:0097060 (0.01) ! synaptic membrane; GO:0071565 (0.01) ! nBAF complex; GO:0071564 (0.01) ! npBAF complex; GO:0070971 (0.01) ! endoplasmic reticulum exit site; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0045169 (0.01) ! fusome; GO:0045111 (0.01) ! intermediate filament cytoskeleton; GO:0044448 (0.01) ! cell cortex part; GO:0044295 (0.01) ! axonal growth cone; GO:0043034 (0.01) ! costamere; GO:0043025 (0.01) ! neuronal cell body; GO:0042383 (0.01) ! sarcolemma; GO:0032044 (0.01) ! DSIF complex; GO:0030658 (0.01) ! transport vesicle membrane; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030175 (0.01) ! filopodium; GO:0030141 (0.01) ! secretory granule; GO:0030134 (0.01) ! ER to Golgi transport vesicle; GO:0030127 (0.01) ! COPII vesicle coat; GO:0030056 (0.01) ! hemidesmosome; GO:0016459 (0.01) ! myosin complex; GO:0014069 (0.01) ! postsynaptic density; GO:0005927 (0.01) ! muscle tendon junction; GO:0005911 (0.01) ! cell-cell junction; GO:0005892 (0.01) ! acetylcholine-gated channel complex; GO:0005891 (0.01) ! voltage-gated calcium channel complex; GO:0005871 (0.01) ! kinesin complex; GO:0005852 (0.01) ! eukaryotic translation initiation factor 3 complex; GO:0005847 (0.01) ! mRNA cleavage and polyadenylation specificity factor complex; GO:0005819 (0.01) ! spindle; GO:0005813 (0.01) ! centrosome; GO:0005794 (0.01) ! Golgi apparatus; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005774 (0.01) ! vacuolar membrane; GO:0005768 (0.01) ! endosome; GO:0005730 (0.01) ! nucleolus; GO:0005665 (0.01) ! DNA-directed RNA polymerase II, core complex; GO:0005605 (0.01) ! basal lamina; GO:0005594 (0.01) ! collagen type IX trimer; GO:0005592 (0.01) ! collagen type XI trimer; GO:0005585 (0.01) ! collagen type II trimer; GO:0005584 (0.01) ! collagen type I trimer; GO:0000790 (0.01) ! nuclear chromatin; GO:0000777 (0.01) ! condensed chromosome kinetochore GO:0005515 ! protein binding 1 GO:0005515 ! protein binding 61411751-61413280 (17q23.2) Lung: 3.77; Prostate: 3.53; Artery - Coronary: 2.90; Artery - Aorta: 2.71; Cervix - Endocervix: 2.65; Bladder: 2.29; Nerve - Tibial: 2.13; Artery - Tibial: 2.11; Uterus: 1.85; Cervix - Ectocervix: 1.80; Fallopian Tube: 1.68; Esophagus - Muscularis: 1.46; Minor Salivary Gland: 1.36; Ovary: 1.34; Testis: 1.26; Esophagus - Gastroesophageal Junction: 1.25; Thyroid: 1.20; Cells - Transformed fibroblasts: 1.13; Breast - Mammary Tissue: 1.08; Adipose - Subcutaneous: 1.07; Vagina: 1.00; Spleen: 0.94; Kidney - Cortex: 0.92; Adrenal Gland: 0.81; Adipose - Visceral (Omentum): 0.69; Pituitary: 0.51; Esophagus - Mucosa: 0.40; Small Intestine - Terminal Ileum: 0.39; Stomach: 0.34; Heart - Atrial Appendage: 0.34; Colon - Transverse: 0.32; Brain - Substantia nigra: 0.32; Skin - Sun Exposed (Lower leg): 0.29; Colon - Sigmoid: 0.27; Heart - Left Ventricle: 0.24; Brain - Hypothalamus: 0.22; Skin - Not Sun Exposed (Suprapubic): 0.22; Brain - Spinal cord (cervical c-1): 0.21; Brain - Caudate (basal ganglia): 0.16; Muscle - Skeletal: 0.16; Brain - Putamen (basal ganglia): 0.15; Brain - Hippocampus: 0.13; Brain - Cortex: 0.13; Brain - Amygdala: 0.12; Brain - Anterior cingulate cortex (BA24): 0.12; Liver: 0.11; Brain - Frontal Cortex (BA9): 0.11; Brain - Nucleus accumbens (basal ganglia): 0.10; Brain - Cerebellum: 0.10; Pancreas: 0.08; Brain - Cerebellar Hemisphere: 0.08; Cells - EBV-transformed lymphocytes: 0.05; MGRPLEGQPLRALDLYPEPAFLRSGKDPKSSPASSPSFAVLGPEVRSTGGQAGSRRRPSAPCSQDRAAAEGAPALLGGSPSSGSPGHPPGSAFGVEAGCRALNVSEHARGGFALGLPFGLSGGAYLFLLLDGAGDPKPTPEAPISSADGRAWFPSESSWQLPQLPAGSTSGSEPRARPGLGPRQLLTGPRDGAAGQGPGRGLTARLGREREIDCGPRQAGHGGTATDTGRAGSGARHRPPRDRGTPGLRTH EFCAB3 EF-hand calcium-binding domain-containing protein 3 EFCB3_HUMAN (Q8N7B9-1) GO:0043169 (0.74) ! cation binding; GO:0005509 (0.47) ! calcium ion binding; GO:0003824 (0.34) ! catalytic activity; GO:0004672 (0.28) ! protein kinase activity; GO:0009931 (0.27) ! calcium-dependent protein serine/threonine kinase activity; GO:0005516 (0.27) ! calmodulin binding; GO:0004683 (0.27) ! calmodulin-dependent protein kinase activity; GO:0008092 (0.13) ! cytoskeletal protein binding; GO:0005198 (0.10) ! structural molecule activity; GO:0003735 (0.07) ! structural constituent of ribosome; GO:0042803 (0.06) ! protein homodimerization activity; GO:0016787 (0.06) ! hydrolase activity; GO:0051393 (0.05) ! alpha-actinin binding; GO:0017166 (0.05) ! vinculin binding; GO:0098772 (0.04) ! molecular function regulator; GO:0032403 (0.04) ! protein complex binding; GO:0008233 (0.04) ! peptidase activity; GO:0003779 (0.04) ! actin binding; GO:0051015 (0.03) ! actin filament binding; GO:0048306 (0.03) ! calcium-dependent protein binding; GO:0030234 (0.03) ! enzyme regulator activity; GO:0004198 (0.03) ! calcium-dependent cysteine-type endopeptidase activity; GO:0022891 (0.02) ! substrate-specific transmembrane transporter activity; GO:0008307 (0.02) ! structural constituent of muscle; GO:1901363 (0.01) ! heterocyclic compound binding; GO:0097159 (0.01) ! organic cyclic compound binding; GO:0055103 (0.01) ! ligase regulator activity; GO:0050839 (0.01) ! cell adhesion molecule binding; GO:0047485 (0.01) ! protein N-terminus binding; GO:0044325 (0.01) ! ion channel binding; GO:0042578 (0.01) ! phosphoric ester hydrolase activity; GO:0035254 (0.01) ! glutamate receptor binding; GO:0032947 (0.01) ! protein complex scaffold; GO:0032036 (0.01) ! myosin heavy chain binding; GO:0031683 (0.01) ! G-protein beta/gamma-subunit complex binding; GO:0031432 (0.01) ! titin binding; GO:0031402 (0.01) ! sodium ion binding; GO:0030898 (0.01) ! actin-dependent ATPase activity; GO:0022836 (0.01) ! gated channel activity; GO:0019904 (0.01) ! protein domain specific binding; GO:0019900 (0.01) ! kinase binding; GO:0015459 (0.01) ! potassium channel regulator activity; GO:0008048 (0.01) ! calcium sensitive guanylate cyclase activator activity; GO:0008017 (0.01) ! microtubule binding; GO:0005347 (0.01) ! ATP transmembrane transporter activity; GO:0005216 (0.01) ! ion channel activity; GO:0004871 (0.01) ! signal transducer activity GO:0009987 (0.80) ! cellular process; GO:0065007 (0.64) ! biological regulation; GO:0071704 (0.61) ! organic substance metabolic process; GO:0050789 (0.61) ! regulation of biological process; GO:0044238 (0.60) ! primary metabolic process; GO:0043170 (0.59) ! macromolecule metabolic process; GO:0019538 (0.58) ! protein metabolic process; GO:0050794 (0.56) ! regulation of cellular process; GO:0044237 (0.55) ! cellular metabolic process; GO:0044260 (0.53) ! cellular macromolecule metabolic process; GO:0044267 (0.52) ! cellular protein metabolic process; GO:0007165 (0.46) ! signal transduction; GO:0050896 (0.43) ! response to stimulus; GO:0035556 (0.43) ! intracellular signal transduction; GO:0006796 (0.42) ! phosphate-containing compound metabolic process; GO:0006464 (0.41) ! cellular protein modification process; GO:0051179 (0.40) ! localization; GO:0006468 (0.40) ! protein phosphorylation; GO:0046777 (0.39) ! protein autophosphorylation; GO:0042221 (0.39) ! response to chemical; GO:0018105 (0.39) ! peptidyl-serine phosphorylation; GO:0051234 (0.38) ! establishment of localization; GO:0010038 (0.37) ! response to metal ion; GO:0009738 (0.34) ! abscisic acid-activated signaling pathway; GO:0044699 (0.32) ! single-organism process; GO:0044763 (0.25) ! single-organism cellular process; GO:0016043 (0.20) ! cellular component organization; GO:0032502 (0.19) ! developmental process; GO:0048856 (0.17) ! anatomical structure development; GO:0044767 (0.17) ! single-organism developmental process; GO:0006996 (0.16) ! organelle organization; GO:1902589 (0.14) ! single-organism organelle organization; GO:0007010 (0.14) ! cytoskeleton organization; GO:0030029 (0.13) ! actin filament-based process; GO:0006807 (0.13) ! nitrogen compound metabolic process; GO:1901576 (0.12) ! organic substance biosynthetic process; GO:1901564 (0.12) ! organonitrogen compound metabolic process; GO:0044249 (0.12) ! cellular biosynthetic process; GO:0034641 (0.12) ! cellular nitrogen compound metabolic process; GO:0030036 (0.12) ! actin cytoskeleton organization; GO:0045214 (0.11) ! sarcomere organization; GO:0032501 (0.11) ! multicellular organismal process; GO:0006412 (0.11) ! translation; GO:0048869 (0.10) ! cellular developmental process; GO:0055002 (0.09) ! striated muscle cell development; GO:0051239 (0.09) ! regulation of multicellular organismal process; GO:0003008 (0.09) ! system process; GO:0065008 (0.08) ! regulation of biological quality; GO:0048741 (0.08) ! skeletal muscle fiber development; GO:0048518 (0.07) ! positive regulation of biological process; GO:0032879 (0.07) ! regulation of localization; GO:0006936 (0.07) ! muscle contraction; GO:0065009 (0.06) ! regulation of molecular function; GO:0051716 (0.06) ! cellular response to stimulus; GO:0048583 (0.06) ! regulation of response to stimulus; GO:0048522 (0.06) ! positive regulation of cellular process; GO:0022607 (0.06) ! cellular component assembly; GO:0006950 (0.06) ! response to stress; GO:0006810 (0.06) ! transport; GO:0006508 (0.06) ! proteolysis; GO:1902578 (0.05) ! single-organism localization; GO:0080090 (0.05) ! regulation of primary metabolic process; GO:0051641 (0.05) ! cellular localization; GO:0051049 (0.05) ! regulation of transport; GO:0048523 (0.05) ! negative regulation of cellular process; GO:0044093 (0.05) ! positive regulation of molecular function; GO:0044057 (0.05) ! regulation of system process; GO:0031323 (0.05) ! regulation of cellular metabolic process; GO:0010941 (0.05) ! regulation of cell death; GO:0009966 (0.05) ! regulation of signal transduction; GO:1902531 (0.04) ! regulation of intracellular signal transduction; GO:0070887 (0.04) ! cellular response to chemical stimulus; GO:0061024 (0.04) ! membrane organization; GO:0060341 (0.04) ! regulation of cellular localization; GO:0060255 (0.04) ! regulation of macromolecule metabolic process; GO:0051592 (0.04) ! response to calcium ion; GO:0051128 (0.04) ! regulation of cellular component organization; GO:0050793 (0.04) ! regulation of developmental process; GO:0050790 (0.04) ! regulation of catalytic activity; GO:0048878 (0.04) ! chemical homeostasis; GO:0048584 (0.04) ! positive regulation of response to stimulus; GO:0044765 (0.04) ! single-organism transport; GO:0043067 (0.04) ! regulation of programmed cell death; GO:0034765 (0.04) ! regulation of ion transmembrane transport; GO:0031326 (0.04) ! regulation of cellular biosynthetic process; GO:0031325 (0.04) ! positive regulation of cellular metabolic process; GO:0022402 (0.04) ! cell cycle process; GO:0019219 (0.04) ! regulation of nucleobase-containing compound metabolic process; GO:0009628 (0.04) ! response to abiotic stimulus; GO:0008104 (0.04) ! protein localization; GO:0006941 (0.04) ! striated muscle contraction; GO:0006937 (0.04) ! regulation of muscle contraction; GO:2000026 (0.03) ! regulation of multicellular organismal development; GO:1904062 (0.03) ! regulation of cation transmembrane transport; GO:1903047 (0.03) ! mitotic cell cycle process; GO:1902580 (0.03) ! single-organism cellular localization; GO:1901700 (0.03) ! response to oxygen-containing compound; GO:0071702 (0.03) ! organic substance transport; GO:0070925 (0.03) ! organelle assembly; GO:0055074 (0.03) ! calcium ion homeostasis; GO:0051050 (0.03) ! positive regulation of transport; GO:0048646 (0.03) ! anatomical structure formation involved in morphogenesis; GO:0048638 (0.03) ! regulation of developmental growth; GO:0045935 (0.03) ! positive regulation of nucleobase-containing compound metabolic process; GO:0044802 (0.03) ! single-organism membrane organization; GO:0042981 (0.03) ! regulation of apoptotic process; GO:0034613 (0.03) ! cellular protein localization; GO:0033554 (0.03) ! cellular response to stress; GO:0032270 (0.03) ! positive regulation of cellular protein metabolic process; GO:0032269 (0.03) ! negative regulation of cellular protein metabolic process; GO:0032101 (0.03) ! regulation of response to external stimulus; GO:0031399 (0.03) ! regulation of protein modification process; GO:0031328 (0.03) ! positive regulation of cellular biosynthetic process; GO:0030003 (0.03) ! cellular cation homeostasis; GO:0022414 (0.03) ! reproductive process; GO:0010959 (0.03) ! regulation of metal ion transport; GO:0010033 (0.03) ! response to organic substance; GO:0006928 (0.03) ! movement of cell or subcellular component; GO:0006461 (0.03) ! protein complex assembly; GO:0006355 (0.03) ! regulation of transcription, DNA-templated; GO:0003009 (0.03) ! skeletal muscle contraction; GO:2000021 (0.02) ! regulation of ion homeostasis; GO:1904064 (0.02) ! positive regulation of cation transmembrane transport; GO:0097264 (0.02) ! self proteolysis; GO:0072657 (0.02) ! protein localization to membrane; GO:0071277 (0.02) ! cellular response to calcium ion; GO:0060048 (0.02) ! cardiac muscle contraction; GO:0051924 (0.02) ! regulation of calcium ion transport; GO:0051606 (0.02) ! detection of stimulus; GO:0051480 (0.02) ! regulation of cytosolic calcium ion concentration; GO:0051336 (0.02) ! regulation of hydrolase activity; GO:0051092 (0.02) ! positive regulation of NF-kappaB transcription factor activity; GO:0051051 (0.02) ! negative regulation of transport; GO:0048585 (0.02) ! negative regulation of response to stimulus; GO:0048513 (0.02) ! animal organ development; GO:0045893 (0.02) ! positive regulation of transcription, DNA-templated; GO:0045892 (0.02) ! negative regulation of transcription, DNA-templated; GO:0045862 (0.02) ! positive regulation of proteolysis; GO:0044710 (0.02) ! single-organism metabolic process; GO:0044707 (0.02) ! single-multicellular organism process; GO:0044702 (0.02) ! single organism reproductive process; GO:0043122 (0.02) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043085 (0.02) ! positive regulation of catalytic activity; GO:0043066 (0.02) ! negative regulation of apoptotic process; GO:0042325 (0.02) ! regulation of phosphorylation; GO:0033234 (0.02) ! negative regulation of protein sumoylation; GO:0033157 (0.02) ! regulation of intracellular protein transport; GO:0032412 (0.02) ! regulation of ion transmembrane transporter activity; GO:0031023 (0.02) ! microtubule organizing center organization; GO:0030239 (0.02) ! myofibril assembly; GO:0030048 (0.02) ! actin filament-based movement; GO:0030030 (0.02) ! cell projection organization; GO:0023057 (0.02) ! negative regulation of signaling; GO:0023056 (0.02) ! positive regulation of signaling; GO:0019722 (0.02) ! calcium-mediated signaling; GO:0016192 (0.02) ! vesicle-mediated transport; GO:0014850 (0.02) ! response to muscle activity; GO:0014718 (0.02) ! positive regulation of satellite cell activation involved in skeletal muscle regeneration; GO:0014070 (0.02) ! response to organic cyclic compound; GO:0010648 (0.02) ! negative regulation of cell communication; GO:0010647 (0.02) ! positive regulation of cell communication; GO:0010564 (0.02) ! regulation of cell cycle process; GO:0010243 (0.02) ! response to organonitrogen compound; GO:0009888 (0.02) ! tissue development; GO:0009653 (0.02) ! anatomical structure morphogenesis; GO:0009605 (0.02) ! response to external stimulus; GO:0007166 (0.02) ! cell surface receptor signaling pathway; GO:0006886 (0.02) ! intracellular protein transport; GO:0003231 (0.02) ! cardiac ventricle development; GO:0000226 (0.02) ! microtubule cytoskeleton organization; GO:2001259 (0.01) ! positive regulation of cation channel activity; GO:2001258 (0.01) ! negative regulation of cation channel activity; GO:2000241 (0.01) ! regulation of reproductive process; GO:1903046 (0.01) ! meiotic cell cycle process; GO:1901990 (0.01) ! regulation of mitotic cell cycle phase transition; GO:1901615 (0.01) ! organic hydroxy compound metabolic process; GO:1901379 (0.01) ! regulation of potassium ion transmembrane transport; GO:1901020 (0.01) ! negative regulation of calcium ion transmembrane transporter activity; GO:1900373 (0.01) ! positive regulation of purine nucleotide biosynthetic process; GO:0098660 (0.01) ! inorganic ion transmembrane transport; GO:0090002 (0.01) ! establishment of protein localization to plasma membrane; GO:0072659 (0.01) ! protein localization to plasma membrane; GO:0072594 (0.01) ! establishment of protein localization to organelle; GO:0071472 (0.01) ! cellular response to salt stress; GO:0071310 (0.01) ! cellular response to organic substance; GO:0070885 (0.01) ! negative regulation of calcineurin-NFAT signaling cascade; GO:0070527 (0.01) ! platelet aggregation; GO:0061061 (0.01) ! muscle structure development; GO:0061025 (0.01) ! membrane fusion; GO:0060314 (0.01) ! regulation of ryanodine-sensitive calcium-release channel activity; GO:0060047 (0.01) ! heart contraction; GO:0055114 (0.01) ! oxidation-reduction process; GO:0055067 (0.01) ! monovalent inorganic cation homeostasis; GO:0055013 (0.01) ! cardiac muscle cell development; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051704 (0.01) ! multi-organism process; GO:0051647 (0.01) ! nucleus localization; GO:0051591 (0.01) ! response to cAMP; GO:0051493 (0.01) ! regulation of cytoskeleton organization; GO:0051349 (0.01) ! positive regulation of lyase activity; GO:0051345 (0.01) ! positive regulation of hydrolase activity; GO:0051300 (0.01) ! spindle pole body organization; GO:0051281 (0.01) ! positive regulation of release of sequestered calcium ion into cytosol; GO:0051240 (0.01) ! positive regulation of multicellular organismal process; GO:0051130 (0.01) ! positive regulation of cellular component organization; GO:0051017 (0.01) ! actin filament bundle assembly; GO:0050921 (0.01) ! positive regulation of chemotaxis; GO:0050850 (0.01) ! positive regulation of calcium-mediated signaling; GO:0048729 (0.01) ! tissue morphogenesis; GO:0048589 (0.01) ! developmental growth; GO:0045913 (0.01) ! positive regulation of carbohydrate metabolic process; GO:0045859 (0.01) ! regulation of protein kinase activity; GO:0045216 (0.01) ! cell-cell junction organization; GO:0045161 (0.01) ! neuronal ion channel clustering; GO:0044351 (0.01) ! macropinocytosis; GO:0044281 (0.01) ! small molecule metabolic process; GO:0043900 (0.01) ! regulation of multi-organism process; GO:0043623 (0.01) ! cellular protein complex assembly; GO:0043462 (0.01) ! regulation of ATPase activity; GO:0043068 (0.01) ! positive regulation of programmed cell death; GO:0042594 (0.01) ! response to starvation; GO:0042335 (0.01) ! cuticle development; GO:0042308 (0.01) ! negative regulation of protein import into nucleus; GO:0042307 (0.01) ! positive regulation of protein import into nucleus; GO:0035690 (0.01) ! cellular response to drug; GO:0034599 (0.01) ! cellular response to oxidative stress; GO:0034329 (0.01) ! cell junction assembly; GO:0033993 (0.01) ! response to lipid; GO:0033365 (0.01) ! protein localization to organelle; GO:0032970 (0.01) ! regulation of actin filament-based process; GO:0032465 (0.01) ! regulation of cytokinesis; GO:0031952 (0.01) ! regulation of protein autophosphorylation; GO:0031401 (0.01) ! positive regulation of protein modification process; GO:0031344 (0.01) ! regulation of cell projection organization; GO:0031282 (0.01) ! regulation of guanylate cyclase activity; GO:0031281 (0.01) ! positive regulation of cyclase activity; GO:0030804 (0.01) ! positive regulation of cyclic nucleotide biosynthetic process; GO:0030335 (0.01) ! positive regulation of cell migration; GO:0030155 (0.01) ! regulation of cell adhesion; GO:0030154 (0.01) ! cell differentiation; GO:0030049 (0.01) ! muscle filament sliding; GO:0030031 (0.01) ! cell projection assembly; GO:0030001 (0.01) ! metal ion transport; GO:0022400 (0.01) ! regulation of rhodopsin mediated signaling pathway; GO:0019233 (0.01) ! sensory perception of pain; GO:0019221 (0.01) ! cytokine-mediated signaling pathway; GO:0016477 (0.01) ! cell migration; GO:0015867 (0.01) ! ATP transport; GO:0010921 (0.01) ! regulation of phosphatase activity; GO:0010769 (0.01) ! regulation of cell morphogenesis involved in differentiation; GO:0009887 (0.01) ! organ morphogenesis; GO:0009725 (0.01) ! response to hormone; GO:0009612 (0.01) ! response to mechanical stimulus; GO:0009611 (0.01) ! response to wounding; GO:0009408 (0.01) ! response to heat; GO:0009057 (0.01) ! macromolecule catabolic process; GO:0008360 (0.01) ! regulation of cell shape; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0007602 (0.01) ! phototransduction; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007507 (0.01) ! heart development; GO:0007275 (0.01) ! multicellular organism development; GO:0007267 (0.01) ! cell-cell signaling; GO:0007264 (0.01) ! small GTPase mediated signal transduction; GO:0007186 (0.01) ! G-protein coupled receptor signaling pathway; GO:0007099 (0.01) ! centriole replication; GO:0007067 (0.01) ! mitotic nuclear division; GO:0006952 (0.01) ! defense response; GO:0006942 (0.01) ! regulation of striated muscle contraction; GO:0006913 (0.01) ! nucleocytoplasmic transport; GO:0006839 (0.01) ! mitochondrial transport; GO:0006644 (0.01) ! phospholipid metabolic process; GO:0006612 (0.01) ! protein targeting to membrane; GO:0006470 (0.01) ! protein dephosphorylation; GO:0006281 (0.01) ! DNA repair; GO:0005513 (0.01) ! detection of calcium ion; GO:0003006 (0.01) ! developmental process involved in reproduction; GO:0002682 (0.01) ! regulation of immune system process; GO:0002576 (0.01) ! platelet degranulation; GO:0002376 (0.01) ! immune system process; GO:0002026 (0.01) ! regulation of the force of heart contraction; GO:0001933 (0.01) ! negative regulation of protein phosphorylation; GO:0001558 (0.01) ! regulation of cell growth; GO:0001101 (0.01) ! response to acid chemical; GO:0000904 (0.01) ! cell morphogenesis involved in differentiation; GO:0000281 (0.01) ! mitotic cytokinesis GO:0044464 (1.00) ! cell part; GO:0044424 (0.99) ! intracellular part; GO:0043226 (0.91) ! organelle; GO:0043229 (0.87) ! intracellular organelle; GO:0043227 (0.82) ! membrane-bounded organelle; GO:0016020 (0.82) ! membrane; GO:0044444 (0.80) ! cytoplasmic part; GO:0043231 (0.80) ! intracellular membrane-bounded organelle; GO:0005737 (0.68) ! cytoplasm; GO:0005886 (0.66) ! plasma membrane; GO:0044422 (0.64) ! organelle part; GO:0005634 (0.62) ! nucleus; GO:0044446 (0.59) ! intracellular organelle part; GO:0044425 (0.56) ! membrane part; GO:0043234 (0.45) ! protein complex; GO:0044459 (0.44) ! plasma membrane part; GO:0005829 (0.39) ! cytosol; GO:0044430 (0.38) ! cytoskeletal part; GO:0097458 (0.33) ! neuron part; GO:0031090 (0.31) ! organelle membrane; GO:0042995 (0.30) ! cell projection; GO:0043232 (0.28) ! intracellular non-membrane-bounded organelle; GO:0044449 (0.26) ! contractile fiber part; GO:0031988 (0.22) ! membrane-bounded vesicle; GO:0044463 (0.21) ! cell projection part; GO:0005739 (0.20) ! mitochondrion; GO:0098796 (0.19) ! membrane protein complex; GO:0031224 (0.19) ! intrinsic component of membrane; GO:0034703 (0.18) ! cation channel complex; GO:0016021 (0.18) ! integral component of membrane; GO:0044421 (0.17) ! extracellular region part; GO:0005743 (0.17) ! mitochondrial inner membrane; GO:0070062 (0.16) ! extracellular exosome; GO:0005856 (0.16) ! cytoskeleton; GO:0030054 (0.15) ! cell junction; GO:0043005 (0.14) ! neuron projection; GO:0098588 (0.13) ! bounding membrane of organelle; GO:0031410 (0.13) ! cytoplasmic vesicle; GO:1902494 (0.12) ! catalytic complex; GO:0098590 (0.12) ! plasma membrane region; GO:0044456 (0.12) ! synapse part; GO:0044441 (0.12) ! ciliary part; GO:0016023 (0.12) ! cytoplasmic, membrane-bounded vesicle; GO:0008076 (0.12) ! voltage-gated potassium channel complex; GO:0005815 (0.12) ! microtubule organizing center; GO:0099503 (0.11) ! secretory vesicle; GO:0034704 (0.11) ! calcium channel complex; GO:0005813 (0.11) ! centrosome; GO:0042641 (0.10) ! actomyosin; GO:0005912 (0.10) ! adherens junction; GO:0044428 (0.09) ! nuclear part; GO:0030863 (0.09) ! cortical cytoskeleton; GO:0030027 (0.09) ! lamellipodium; GO:0005925 (0.09) ! focal adhesion; GO:0005911 (0.09) ! cell-cell junction; GO:0005861 (0.09) ! troponin complex; GO:0001725 (0.09) ! stress fiber; GO:1990357 (0.08) ! terminal web; GO:0099513 (0.08) ! polymeric cytoskeletal fiber; GO:0097433 (0.08) ! dense body; GO:0090637 (0.08) ! inner dense plaque of desmosome; GO:0090636 (0.08) ! outer dense plaque of desmosome; GO:0072372 (0.08) ! primary cilium; GO:0045202 (0.08) ! synapse; GO:0042383 (0.08) ! sarcolemma; GO:0031252 (0.08) ! cell leading edge; GO:0030486 (0.08) ! smooth muscle dense body; GO:0016328 (0.08) ! lateral plasma membrane; GO:0005923 (0.08) ! bicellular tight junction; GO:0005915 (0.08) ! zonula adherens; GO:0005622 (0.08) ! intracellular; GO:0031253 (0.07) ! cell projection membrane; GO:0030427 (0.07) ! site of polarized growth; GO:0030425 (0.07) ! dendrite; GO:0030424 (0.07) ! axon; GO:0030133 (0.07) ! transport vesicle; GO:0030017 (0.07) ! sarcomere; GO:0005955 (0.07) ! calcineurin complex; GO:0005819 (0.07) ! spindle; GO:0005794 (0.07) ! Golgi apparatus; GO:0005654 (0.07) ! nucleoplasm; GO:0005576 (0.07) ! extracellular region; GO:0001750 (0.07) ! photoreceptor outer segment; GO:0000922 (0.07) ! spindle pole; GO:0000139 (0.07) ! Golgi membrane; GO:1990246 (0.06) ! uniplex complex; GO:0097381 (0.06) ! photoreceptor disc membrane; GO:0048471 (0.06) ! perinuclear region of cytoplasm; GO:0045211 (0.06) ! postsynaptic membrane; GO:0043209 (0.06) ! myelin sheath; GO:0036156 (0.06) ! inner dynein arm; GO:0033101 (0.06) ! cellular bud membrane; GO:0032592 (0.06) ! integral component of mitochondrial membrane; GO:0032153 (0.06) ! cell division site; GO:0031045 (0.06) ! dense core granule; GO:0030426 (0.06) ! growth cone; GO:0014069 (0.06) ! postsynaptic density; GO:0008021 (0.06) ! synaptic vesicle; GO:0005887 (0.06) ! integral component of plasma membrane; GO:0005876 (0.06) ! spindle microtubule; GO:0005758 (0.06) ! mitochondrial intermembrane space; GO:0016459 (0.04) ! myosin complex; GO:0044450 (0.03) ! microtubule organizing center part; GO:0043292 (0.03) ! contractile fiber; GO:0030018 (0.03) ! Z disc; GO:0016460 (0.03) ! myosin II complex; GO:0030315 (0.02) ! T-tubule; GO:0030016 (0.02) ! myofibril; GO:0005814 (0.02) ! centriole; GO:0005783 (0.02) ! endoplasmic reticulum; GO:0098858 (0.01) ! actin-based cell projection; GO:0072686 (0.01) ! mitotic spindle; GO:0071942 (0.01) ! XPC complex; GO:0055120 (0.01) ! striated muscle dense body; GO:0044432 (0.01) ! endoplasmic reticulum part; GO:0043679 (0.01) ! axon terminus; GO:0036064 (0.01) ! ciliary basal body; GO:0033270 (0.01) ! paranode region of axon; GO:0032587 (0.01) ! ruffle membrane; GO:0032391 (0.01) ! photoreceptor connecting cilium; GO:0031965 (0.01) ! nuclear membrane; GO:0031476 (0.01) ! myosin VI complex; GO:0030529 (0.01) ! intracellular ribonucleoprotein complex; GO:0015630 (0.01) ! microtubule cytoskeleton; GO:0015629 (0.01) ! actin cytoskeleton; GO:0005903 (0.01) ! brush border; GO:0005884 (0.01) ! actin filament; GO:0005865 (0.01) ! striated muscle thin filament; GO:0005859 (0.01) ! muscle myosin complex; GO:0005774 (0.01) ! vacuolar membrane; GO:0005623 (0.01) ! cell; GO:0005615 (0.01) ! extracellular space; GO:0001917 (0.01) ! photoreceptor inner segment; GO:0001891 (0.01) ! phagocytic cup; GO:0000331 (0.01) ! contractile vacuole GO:0005509 ! calcium ion binding; GO:0046872 ! metal ion binding 2 GO:0005509 ! calcium ion binding 62343941-62416479 (17q23.2) Testis: 6.95; Brain - Frontal Cortex (BA9): 0.01; MAVSEIKPKLKLNPLTKVPISHNKRDRDLPGSLQCQLQHKEKKLSASQMAAFQDAYNFFYKDKTGCIDFHGLMCTVAKLGMNLTKHDVYNELKCADIDRDGKVNFSDFIKVLTDKNLFLKAVVPEKETCLDLAGNPGILLFEILSRLLETSALPRKSIIEIVSYFQRKFQHTGPGMLWSPYTMGYGKRTLKPDICTPPSSSMAAFANAARIAIMKEKDLFKFLEELKRCNSGSDSPYSKIPIFPLFPNVDGVVMGKPFKDMQKLEMLRIKEPLHFFEDYFFHKRDWKTQAANIKSMDPASGYSNNIFTIDQMLKKKQTCTVADATAIKQHVKRATDTYNLGIALEHRKEMLNLWQKIRGDLIGMDSRNESFYDTFSTYTWSWNVCQELLSPKDLRLYDAYVNRNSSHNSRSSSSSDTSECYTDSGRKRKRKGLKGFQQ CEP95 Centrosomal protein of 95 kDa CEP95_HUMAN (Q96GE4-1) GO:0035639 (0.32) ! purine ribonucleoside triphosphate binding; GO:0032559 (0.32) ! adenyl ribonucleotide binding; GO:0032550 (0.32) ! purine ribonucleoside binding; GO:0003676 (0.32) ! nucleic acid binding; GO:0003824 (0.29) ! catalytic activity GO:0009987 (0.71) ! cellular process; GO:0044699 (0.61) ! single-organism process; GO:0044763 (0.55) ! single-organism cellular process; GO:0016043 (0.38) ! cellular component organization; GO:0065007 (0.37) ! biological regulation; GO:0050789 (0.36) ! regulation of biological process; GO:0050794 (0.35) ! regulation of cellular process; GO:0051179 (0.27) ! localization; GO:0007017 (0.26) ! microtubule-based process; GO:0032502 (0.25) ! developmental process; GO:0006928 (0.25) ! movement of cell or subcellular component; GO:0044767 (0.24) ! single-organism developmental process; GO:0008152 (0.23) ! metabolic process; GO:0006996 (0.23) ! organelle organization; GO:0071704 (0.22) ! organic substance metabolic process; GO:0044238 (0.22) ! primary metabolic process; GO:0044237 (0.22) ! cellular metabolic process; GO:0051641 (0.21) ! cellular localization; GO:0051234 (0.20) ! establishment of localization; GO:0044260 (0.20) ! cellular macromolecule metabolic process; GO:0051128 (0.19) ! regulation of cellular component organization; GO:0080090 (0.18) ! regulation of primary metabolic process; GO:0031323 (0.18) ! regulation of cellular metabolic process; GO:0007018 (0.18) ! microtubule-based movement; GO:0006810 (0.18) ! transport; GO:0060255 (0.17) ! regulation of macromolecule metabolic process; GO:0048519 (0.17) ! negative regulation of biological process; GO:0043412 (0.17) ! macromolecule modification; GO:1902589 (0.16) ! single-organism organelle organization; GO:0051649 (0.16) ! establishment of localization in cell; GO:0048523 (0.16) ! negative regulation of cellular process; GO:1901360 (0.15) ! organic cyclic compound metabolic process; GO:0048856 (0.15) ! anatomical structure development; GO:0034641 (0.15) ! cellular nitrogen compound metabolic process; GO:0006725 (0.15) ! cellular aromatic compound metabolic process; GO:0048869 (0.14) ! cellular developmental process; GO:0033036 (0.14) ! macromolecule localization; GO:0032501 (0.14) ! multicellular organismal process; GO:0022607 (0.14) ! cellular component assembly; GO:0007010 (0.14) ! cytoskeleton organization; GO:0006139 (0.14) ! nucleobase-containing compound metabolic process; GO:0090304 (0.13) ! nucleic acid metabolic process; GO:0019538 (0.13) ! protein metabolic process; GO:0048522 (0.12) ! positive regulation of cellular process; GO:0044267 (0.12) ! cellular protein metabolic process; GO:0032268 (0.12) ! regulation of cellular protein metabolic process; GO:0010468 (0.12) ! regulation of gene expression; GO:0006259 (0.12) ! DNA metabolic process; GO:2000112 (0.11) ! regulation of cellular macromolecule biosynthetic process; GO:0090305 (0.11) ! nucleic acid phosphodiester bond hydrolysis; GO:0051171 (0.11) ! regulation of nitrogen compound metabolic process; GO:0046907 (0.11) ! intracellular transport; GO:0043933 (0.11) ! macromolecular complex subunit organization; GO:0022402 (0.11) ! cell cycle process; GO:0009653 (0.11) ! anatomical structure morphogenesis; GO:0006464 (0.11) ! cellular protein modification process; GO:0006306 (0.11) ! DNA methylation; GO:0033043 (0.10) ! regulation of organelle organization; GO:0009892 (0.10) ! negative regulation of metabolic process; GO:0006355 (0.10) ! regulation of transcription, DNA-templated; GO:0050896 (0.09) ! response to stimulus; GO:0031324 (0.09) ! negative regulation of cellular metabolic process; GO:0030029 (0.09) ! actin filament-based process; GO:0023051 (0.09) ! regulation of signaling; GO:0010646 (0.09) ! regulation of cell communication; GO:0010605 (0.09) ! negative regulation of macromolecule metabolic process; GO:0008104 (0.09) ! protein localization; GO:0003008 (0.09) ! system process; GO:1903047 (0.08) ! mitotic cell cycle process; GO:1902578 (0.08) ! single-organism localization; GO:0070925 (0.08) ! organelle assembly; GO:0070727 (0.08) ! cellular macromolecule localization; GO:0065008 (0.08) ! regulation of biological quality; GO:0048583 (0.08) ! regulation of response to stimulus; GO:0045892 (0.08) ! negative regulation of transcription, DNA-templated; GO:0051726 (0.07) ! regulation of cell cycle; GO:0050793 (0.07) ! regulation of developmental process; GO:0048646 (0.07) ! anatomical structure formation involved in morphogenesis; GO:0034645 (0.07) ! cellular macromolecule biosynthetic process; GO:0030030 (0.07) ! cell projection organization; GO:0016192 (0.07) ! vesicle-mediated transport; GO:0016070 (0.07) ! RNA metabolic process; GO:0009966 (0.07) ! regulation of signal transduction; GO:0000226 (0.07) ! microtubule cytoskeleton organization; GO:0065009 (0.06) ! regulation of molecular function; GO:0051493 (0.06) ! regulation of cytoskeleton organization; GO:0051239 (0.06) ! regulation of multicellular organismal process; GO:0044765 (0.06) ! single-organism transport; GO:0044707 (0.06) ! single-multicellular organism process; GO:0044265 (0.06) ! cellular macromolecule catabolic process; GO:0043244 (0.06) ! regulation of protein complex disassembly; GO:0032989 (0.06) ! cellular component morphogenesis; GO:0032879 (0.06) ! regulation of localization; GO:0031325 (0.06) ! positive regulation of cellular metabolic process; GO:0030705 (0.06) ! cytoskeleton-dependent intracellular transport; GO:0030036 (0.06) ! actin cytoskeleton organization; GO:0019220 (0.06) ! regulation of phosphate metabolic process; GO:0016567 (0.06) ! protein ubiquitination; GO:0016071 (0.06) ! mRNA metabolic process; GO:0010604 (0.06) ! positive regulation of macromolecule metabolic process; GO:0010564 (0.06) ! regulation of cell cycle process; GO:0006417 (0.06) ! regulation of translation; GO:0006325 (0.06) ! chromatin organization; GO:0006310 (0.06) ! DNA recombination; GO:0005975 (0.06) ! carbohydrate metabolic process; GO:2000026 (0.05) ! regulation of multicellular organismal development; GO:0071822 (0.05) ! protein complex subunit organization; GO:0071702 (0.05) ! organic substance transport; GO:0070478 (0.05) ! nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; GO:0065003 (0.05) ! macromolecular complex assembly; GO:0051640 (0.05) ! organelle localization; GO:0050790 (0.05) ! regulation of catalytic activity; GO:0045184 (0.05) ! establishment of protein localization; GO:0040011 (0.05) ! locomotion; GO:0032270 (0.05) ! positive regulation of cellular protein metabolic process; GO:0030466 (0.05) ! chromatin silencing at silent mating-type cassette; GO:0030245 (0.05) ! cellulose catabolic process; GO:0030154 (0.05) ! cell differentiation; GO:0022414 (0.05) ! reproductive process; GO:0010927 (0.05) ! cellular component assembly involved in morphogenesis; GO:0008298 (0.05) ! intracellular mRNA localization; GO:0007165 (0.05) ! signal transduction; GO:0006796 (0.05) ! phosphate-containing compound metabolic process; GO:0006452 (0.05) ! translational frameshifting; GO:0006449 (0.05) ! regulation of translational termination; GO:0001932 (0.05) ! regulation of protein phosphorylation; GO:1902580 (0.04) ! single-organism cellular localization; GO:1902531 (0.04) ! regulation of intracellular signal transduction; GO:0051716 (0.04) ! cellular response to stimulus; GO:0051656 (0.04) ! establishment of organelle localization; GO:0051130 (0.04) ! positive regulation of cellular component organization; GO:0048870 (0.04) ! cell motility; GO:0048468 (0.04) ! cell development; GO:0045595 (0.04) ! regulation of cell differentiation; GO:0044702 (0.04) ! single organism reproductive process; GO:0044087 (0.04) ! regulation of cellular component biogenesis; GO:0034622 (0.04) ! cellular macromolecular complex assembly; GO:0032970 (0.04) ! regulation of actin filament-based process; GO:0031032 (0.04) ! actomyosin structure organization; GO:0030048 (0.04) ! actin filament-based movement; GO:0022604 (0.04) ! regulation of cell morphogenesis; GO:0015031 (0.04) ! protein transport; GO:0009968 (0.04) ! negative regulation of signal transduction; GO:0007600 (0.04) ! sensory perception; GO:0006950 (0.04) ! response to stress; GO:0006936 (0.04) ! muscle contraction; GO:0006468 (0.04) ! protein phosphorylation; GO:0006461 (0.04) ! protein complex assembly; GO:0001934 (0.04) ! positive regulation of protein phosphorylation; GO:1902582 (0.03) ! single-organism intracellular transport; GO:1901990 (0.03) ! regulation of mitotic cell cycle phase transition; GO:0097485 (0.03) ! neuron projection guidance; GO:0061024 (0.03) ! membrane organization; GO:0060284 (0.03) ! regulation of cell development; GO:0051783 (0.03) ! regulation of nuclear division; GO:0051336 (0.03) ! regulation of hydrolase activity; GO:0051297 (0.03) ! centrosome organization; GO:0051240 (0.03) ! positive regulation of multicellular organismal process; GO:0051129 (0.03) ! negative regulation of cellular component organization; GO:0051049 (0.03) ! regulation of transport; GO:0048729 (0.03) ! tissue morphogenesis; GO:0048584 (0.03) ! positive regulation of response to stimulus; GO:0048513 (0.03) ! animal organ development; GO:0044710 (0.03) ! single-organism metabolic process; GO:0043623 (0.03) ! cellular protein complex assembly; GO:0043085 (0.03) ! positive regulation of catalytic activity; GO:0042221 (0.03) ! response to chemical; GO:0035556 (0.03) ! intracellular signal transduction; GO:0034613 (0.03) ! cellular protein localization; GO:0033554 (0.03) ! cellular response to stress; GO:0033044 (0.03) ! regulation of chromosome organization; GO:0032956 (0.03) ! regulation of actin cytoskeleton organization; GO:0032886 (0.03) ! regulation of microtubule-based process; GO:0030031 (0.03) ! cell projection assembly; GO:0009888 (0.03) ! tissue development; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0007610 (0.03) ! behavior; GO:0007020 (0.03) ! microtubule nucleation; GO:0006941 (0.03) ! striated muscle contraction; GO:0006913 (0.03) ! nucleocytoplasmic transport; GO:0006886 (0.03) ! intracellular protein transport; GO:0000910 (0.03) ! cytokinesis; GO:0000902 (0.03) ! cell morphogenesis; GO:0000075 (0.03) ! cell cycle checkpoint; GO:2000145 (0.02) ! regulation of cell motility; GO:1903046 (0.02) ! meiotic cell cycle process; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:1902532 (0.02) ! negative regulation of intracellular signal transduction; GO:1901564 (0.02) ! organonitrogen compound metabolic process; GO:0080135 (0.02) ! regulation of cellular response to stress; GO:0071705 (0.02) ! nitrogen compound transport; GO:0071688 (0.02) ! striated muscle myosin thick filament assembly; GO:0070887 (0.02) ! cellular response to chemical stimulus; GO:0070252 (0.02) ! actin-mediated cell contraction; GO:0060341 (0.02) ! regulation of cellular localization; GO:0060271 (0.02) ! cilium morphogenesis; GO:0055001 (0.02) ! muscle cell development; GO:0051704 (0.02) ! multi-organism process; GO:0051276 (0.02) ! chromosome organization; GO:0051225 (0.02) ! spindle assembly; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0048589 (0.02) ! developmental growth; GO:0048193 (0.02) ! Golgi vesicle transport; GO:0045859 (0.02) ! regulation of protein kinase activity; GO:0044708 (0.02) ! single-organism behavior; GO:0044271 (0.02) ! cellular nitrogen compound biosynthetic process; GO:0044089 (0.02) ! positive regulation of cellular component biogenesis; GO:0043408 (0.02) ! regulation of MAPK cascade; GO:0043087 (0.02) ! regulation of GTPase activity; GO:0042384 (0.02) ! cilium assembly; GO:0042127 (0.02) ! regulation of cell proliferation; GO:0040008 (0.02) ! regulation of growth; GO:0034330 (0.02) ! cell junction organization; GO:0033365 (0.02) ! protein localization to organelle; GO:0032880 (0.02) ! regulation of protein localization; GO:0030865 (0.02) ! cortical cytoskeleton organization; GO:0030855 (0.02) ! epithelial cell differentiation; GO:0030239 (0.02) ! myofibril assembly; GO:0030198 (0.02) ! extracellular matrix organization; GO:0023061 (0.02) ! signal release; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0022411 (0.02) ! cellular component disassembly; GO:0016477 (0.02) ! cell migration; GO:0010975 (0.02) ! regulation of neuron projection development; GO:0010824 (0.02) ! regulation of centrosome duplication; GO:0010720 (0.02) ! positive regulation of cell development; GO:0010628 (0.02) ! positive regulation of gene expression; GO:0010033 (0.02) ! response to organic substance; GO:0009887 (0.02) ! organ morphogenesis; GO:0009605 (0.02) ! response to external stimulus; GO:0008360 (0.02) ! regulation of cell shape; GO:0007626 (0.02) ! locomotory behavior; GO:0007605 (0.02) ! sensory perception of sound; GO:0007411 (0.02) ! axon guidance; GO:0007389 (0.02) ! pattern specification process; GO:0007275 (0.02) ! multicellular organism development; GO:0007166 (0.02) ! cell surface receptor signaling pathway; GO:0007163 (0.02) ! establishment or maintenance of cell polarity; GO:0007155 (0.02) ! cell adhesion; GO:0007154 (0.02) ! cell communication; GO:0007094 (0.02) ! mitotic spindle assembly checkpoint; GO:0007033 (0.02) ! vacuole organization; GO:0007015 (0.02) ! actin filament organization; GO:0006974 (0.02) ! cellular response to DNA damage stimulus; GO:0006897 (0.02) ! endocytosis; GO:0006357 (0.02) ! regulation of transcription from RNA polymerase II promoter; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0000904 (0.02) ! cell morphogenesis involved in differentiation; GO:0000281 (0.02) ! mitotic cytokinesis; GO:2000241 (0.01) ! regulation of reproductive process; GO:1990778 (0.01) ! protein localization to cell periphery; GO:1903923 (0.01) ! positive regulation of protein processing in phagocytic vesicle; GO:1903919 (0.01) ! negative regulation of actin filament severing; GO:1903008 (0.01) ! organelle disassembly; GO:1902017 (0.01) ! regulation of cilium assembly; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:0098542 (0.01) ! defense response to other organism; GO:0090630 (0.01) ! activation of GTPase activity; GO:0090316 (0.01) ! positive regulation of intracellular protein transport; GO:0090307 (0.01) ! mitotic spindle assembly; GO:0090222 (0.01) ! centrosome-templated microtubule nucleation; GO:0090175 (0.01) ! regulation of establishment of planar polarity; GO:0090068 (0.01) ! positive regulation of cell cycle process; GO:0090002 (0.01) ! establishment of protein localization to plasma membrane; GO:0072698 (0.01) ! protein localization to microtubule cytoskeleton; GO:0072657 (0.01) ! protein localization to membrane; GO:0071896 (0.01) ! protein localization to adherens junction; GO:0071417 (0.01) ! cellular response to organonitrogen compound; GO:0071345 (0.01) ! cellular response to cytokine stimulus; GO:0071103 (0.01) ! DNA conformation change; GO:0061572 (0.01) ! actin filament bundle organization; GO:0061077 (0.01) ! chaperone-mediated protein folding; GO:0061025 (0.01) ! membrane fusion; GO:0060429 (0.01) ! epithelium development; GO:0060287 (0.01) ! epithelial cilium movement involved in determination of left/right asymmetry; GO:0060285 (0.01) ! cilium-dependent cell motility; GO:0060249 (0.01) ! anatomical structure homeostasis; GO:0060047 (0.01) ! heart contraction; GO:0055085 (0.01) ! transmembrane transport; GO:0055010 (0.01) ! ventricular cardiac muscle tissue morphogenesis; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051893 (0.01) ! regulation of focal adhesion assembly; GO:0051642 (0.01) ! centrosome localization; GO:0051495 (0.01) ! positive regulation of cytoskeleton organization; GO:0051492 (0.01) ! regulation of stress fiber assembly; GO:0051415 (0.01) ! interphase microtubule nucleation by interphase microtubule organizing center; GO:0051298 (0.01) ! centrosome duplication; GO:0051272 (0.01) ! positive regulation of cellular component movement; GO:0051241 (0.01) ! negative regulation of multicellular organismal process; GO:0051153 (0.01) ! regulation of striated muscle cell differentiation; GO:0051124 (0.01) ! synaptic growth at neuromuscular junction; GO:0051093 (0.01) ! negative regulation of developmental process; GO:0051052 (0.01) ! regulation of DNA metabolic process; GO:0051051 (0.01) ! negative regulation of transport; GO:0050906 (0.01) ! detection of stimulus involved in sensory perception; GO:0050773 (0.01) ! regulation of dendrite development; GO:0050770 (0.01) ! regulation of axonogenesis; GO:0048812 (0.01) ! neuron projection morphogenesis; GO:0048790 (0.01) ! maintenance of presynaptic active zone structure; GO:0048789 (0.01) ! cytoskeletal matrix organization at active zone; GO:0048739 (0.01) ! cardiac muscle fiber development; GO:0048638 (0.01) ! regulation of developmental growth; GO:0048488 (0.01) ! synaptic vesicle endocytosis; GO:0048477 (0.01) ! oogenesis; GO:0048211 (0.01) ! Golgi vesicle docking; GO:0048167 (0.01) ! regulation of synaptic plasticity; GO:0047496 (0.01) ! vesicle transport along microtubule; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046627 (0.01) ! negative regulation of insulin receptor signaling pathway; GO:0046580 (0.01) ! negative regulation of Ras protein signal transduction; GO:0046330 (0.01) ! positive regulation of JNK cascade; GO:0046034 (0.01) ! ATP metabolic process; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045926 (0.01) ! negative regulation of growth; GO:0045785 (0.01) ! positive regulation of cell adhesion; GO:0045214 (0.01) ! sarcomere organization; GO:0045197 (0.01) ! establishment or maintenance of epithelial cell apical/basal polarity; GO:0045176 (0.01) ! apical protein localization; GO:0045165 (0.01) ! cell fate commitment; GO:0045056 (0.01) ! transcytosis; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0044351 (0.01) ! macropinocytosis; GO:0043900 (0.01) ! regulation of multi-organism process; GO:0043405 (0.01) ! regulation of MAP kinase activity; GO:0043086 (0.01) ! negative regulation of catalytic activity; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0042391 (0.01) ! regulation of membrane potential; GO:0042246 (0.01) ! tissue regeneration; GO:0042147 (0.01) ! retrograde transport, endosome to Golgi; GO:0040019 (0.01) ! positive regulation of embryonic development; GO:0040017 (0.01) ! positive regulation of locomotion; GO:0035317 (0.01) ! imaginal disc-derived wing hair organization; GO:0035304 (0.01) ! regulation of protein dephosphorylation; GO:0035295 (0.01) ! tube development; GO:0035239 (0.01) ! tube morphogenesis; GO:0035107 (0.01) ! appendage morphogenesis; GO:0034454 (0.01) ! microtubule anchoring at centrosome; GO:0034341 (0.01) ! response to interferon-gamma; GO:0034333 (0.01) ! adherens junction assembly; GO:0032868 (0.01) ! response to insulin; GO:0032844 (0.01) ! regulation of homeostatic process; GO:0032507 (0.01) ! maintenance of protein location in cell; GO:0032506 (0.01) ! cytokinetic process; GO:0032465 (0.01) ! regulation of cytokinesis; GO:0032271 (0.01) ! regulation of protein polymerization; GO:0032147 (0.01) ! activation of protein kinase activity; GO:0032007 (0.01) ! negative regulation of TOR signaling; GO:0031667 (0.01) ! response to nutrient levels; GO:0031647 (0.01) ! regulation of protein stability; GO:0031589 (0.01) ! cell-substrate adhesion; GO:0031581 (0.01) ! hemidesmosome assembly; GO:0031572 (0.01) ! G2 DNA damage checkpoint; GO:0031532 (0.01) ! actin cytoskeleton reorganization; GO:0031503 (0.01) ! protein complex localization; GO:0031444 (0.01) ! slow-twitch skeletal muscle fiber contraction; GO:0031338 (0.01) ! regulation of vesicle fusion; GO:0031175 (0.01) ! neuron projection development; GO:0031122 (0.01) ! cytoplasmic microtubule organization; GO:0030866 (0.01) ! cortical actin cytoskeleton organization; GO:0030856 (0.01) ! regulation of epithelial cell differentiation; GO:0030512 (0.01) ! negative regulation of transforming growth factor beta receptor signaling pathway; GO:0030241 (0.01) ! skeletal muscle myosin thick filament assembly; GO:0030240 (0.01) ! skeletal muscle thin filament assembly; GO:0030216 (0.01) ! keratinocyte differentiation; GO:0030182 (0.01) ! neuron differentiation; GO:0030111 (0.01) ! regulation of Wnt signaling pathway; GO:0030049 (0.01) ! muscle filament sliding; GO:0030010 (0.01) ! establishment of cell polarity; GO:0022617 (0.01) ! extracellular matrix disassembly; GO:0022008 (0.01) ! neurogenesis; GO:0021987 (0.01) ! cerebral cortex development; GO:0019233 (0.01) ! sensory perception of pain; GO:0018193 (0.01) ! peptidyl-amino acid modification; GO:0018149 (0.01) ! peptide cross-linking; GO:0016337 (0.01) ! single organismal cell-cell adhesion; GO:0016319 (0.01) ! mushroom body development; GO:0016055 (0.01) ! Wnt signaling pathway; GO:0016050 (0.01) ! vesicle organization; GO:0016049 (0.01) ! cell growth; GO:0016032 (0.01) ! viral process; GO:0014823 (0.01) ! response to activity; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0010976 (0.01) ! positive regulation of neuron projection development; GO:0010959 (0.01) ! regulation of metal ion transport; GO:0010921 (0.01) ! regulation of phosphatase activity; GO:0010631 (0.01) ! epithelial cell migration; GO:0010506 (0.01) ! regulation of autophagy; GO:0010389 (0.01) ! regulation of G2/M transition of mitotic cell cycle; GO:0010224 (0.01) ! response to UV-B; GO:0009886 (0.01) ! post-embryonic morphogenesis; GO:0009880 (0.01) ! embryonic pattern specification; GO:0009798 (0.01) ! axis specification; GO:0009612 (0.01) ! response to mechanical stimulus; GO:0009582 (0.01) ! detection of abiotic stimulus; GO:0009581 (0.01) ! detection of external stimulus; GO:0009408 (0.01) ! response to heat; GO:0008608 (0.01) ! attachment of spindle microtubules to kinetochore; GO:0008544 (0.01) ! epidermis development; GO:0008361 (0.01) ! regulation of cell size; GO:0008356 (0.01) ! asymmetric cell division; GO:0008344 (0.01) ! adult locomotory behavior; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008064 (0.01) ! regulation of actin polymerization or depolymerization; GO:0007615 (0.01) ! anesthesia-resistant memory; GO:0007614 (0.01) ! short-term memory; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007517 (0.01) ! muscle organ development; GO:0007512 (0.01) ! adult heart development; GO:0007420 (0.01) ! brain development; GO:0007399 (0.01) ! nervous system development; GO:0007274 (0.01) ! neuromuscular synaptic transmission; GO:0007269 (0.01) ! neurotransmitter secretion; GO:0007266 (0.01) ! Rho protein signal transduction; GO:0007169 (0.01) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007131 (0.01) ! reciprocal meiotic recombination; GO:0007126 (0.01) ! meiotic nuclear division; GO:0007099 (0.01) ! centriole replication; GO:0007097 (0.01) ! nuclear migration; GO:0007067 (0.01) ! mitotic nuclear division; GO:0007062 (0.01) ! sister chromatid cohesion; GO:0007059 (0.01) ! chromosome segregation; GO:0007052 (0.01) ! mitotic spindle organization; GO:0007043 (0.01) ! cell-cell junction assembly; GO:0007030 (0.01) ! Golgi organization; GO:0007009 (0.01) ! plasma membrane organization; GO:0007005 (0.01) ! mitochondrion organization; GO:0006997 (0.01) ! nucleus organization; GO:0006955 (0.01) ! immune response; GO:0006911 (0.01) ! phagocytosis, engulfment; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006811 (0.01) ! ion transport; GO:0006629 (0.01) ! lipid metabolic process; GO:0006606 (0.01) ! protein import into nucleus; GO:0006508 (0.01) ! proteolysis; GO:0006446 (0.01) ! regulation of translational initiation; GO:0006412 (0.01) ! translation; GO:0006406 (0.01) ! mRNA export from nucleus; GO:0006351 (0.01) ! transcription, DNA-templated; GO:0006338 (0.01) ! chromatin remodeling; GO:0006281 (0.01) ! DNA repair; GO:0006109 (0.01) ! regulation of carbohydrate metabolic process; GO:0003198 (0.01) ! epithelial to mesenchymal transition involved in endocardial cushion formation; GO:0002685 (0.01) ! regulation of leukocyte migration; GO:0002684 (0.01) ! positive regulation of immune system process; GO:0002521 (0.01) ! leukocyte differentiation; GO:0002064 (0.01) ! epithelial cell development; GO:0002027 (0.01) ! regulation of heart rate; GO:0002009 (0.01) ! morphogenesis of an epithelium; GO:0001933 (0.01) ! negative regulation of protein phosphorylation; GO:0001817 (0.01) ! regulation of cytokine production; GO:0001736 (0.01) ! establishment of planar polarity; GO:0001701 (0.01) ! in utero embryonic development; GO:0001558 (0.01) ! regulation of cell growth; GO:0001525 (0.01) ! angiogenesis; GO:0000398 (0.01) ! mRNA splicing, via spliceosome; GO:0000278 (0.01) ! mitotic cell cycle; GO:0000132 (0.01) ! establishment of mitotic spindle orientation; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter; GO:0000086 (0.01) ! G2/M transition of mitotic cell cycle; GO:0000045 (0.01) ! autophagosome assembly; GO:0000022 (0.01) ! mitotic spindle elongation GO:0005813 (1.00) ! centrosome; GO:0000922 (1.00) ! spindle pole GO:0005813 ! centrosome; GO:0000922 ! spindle pole; GO:0005515 ! protein binding GO:0005815 ! microtubule organizing center; GO:0005737 ! cytoplasm; GO:0005856 ! cytoskeleton 4 GO:0005515 ! protein binding 64506588-64542461 (17q23.3) High: stomach 2 (glandular cells);small intestine (glandular cells);epididymis (glandular cells);appendix (glandular cells);colon (glandular cells);ovary (follicle cells);urinary bladder (urothelial cells);rectum (glandular cells);duodenum (glandular cells);Medium: stomach 1 (glandular cells);seminal vesicle (glandular cells);lung (macrophages; pneumocytes);gallbladder (glandular cells);kidney (cells in tubules);testis (Leydig cells);tonsil (squamous epithelial cells);endometrium 1 (cells in endometrial stroma; glandular cells);vagina (squamous epithelial cells);salivary gland (glandular cells);smooth muscle (smooth muscle cells);cerebral cortex (endothelial cells);hippocampus (neuronal cells);bronchus (respiratory epithelial cells);breast (myoepithelial cells);prostate (glandular cells);cervix, uterine (glandular cells; squamous epithelial cells);pancreas (islets of Langerhans);cerebellum (Purkinje cells);fallopian tube (glandular cells);soft tissue 1 (fibroblasts);soft tissue 2 (fibroblasts);nasopharynx (respiratory epithelial cells);oral mucosa (squamous epithelial cells);heart muscle (myocytes);Low: placenta (decidual cells; trophoblastic cells);testis (cells in seminiferous ducts);caudate (neuronal cells);skin 1 (fibroblasts; keratinocytes; Langerhans; melanocytes);tonsil (non-germinal center cells);skeletal muscle (myocytes);skin 2 (epidermal cells);adrenal gland (glandular cells);endometrium 2 (glandular cells);colon (endothelial cells);breast (glandular cells);thyroid gland (glandular cells);esophagus (squamous epithelial cells);pancreas (exocrine glandular cells);cerebral cortex (neuronal cells; neuropil);kidney (cells in glomeruli);liver (bile duct cells); Ovary: 58.72; Thyroid: 51.52; Cervix - Endocervix: 50.88; Nerve - Tibial: 44.45; Brain - Cerebellar Hemisphere: 43.59; Testis: 43.59; Uterus: 39.58; Fallopian Tube: 38.16; Brain - Cerebellum: 37.24; Cervix - Ectocervix: 36.86; Prostate: 32.93; Colon - Sigmoid: 29.49; Skin - Not Sun Exposed (Suprapubic): 29.06; Vagina: 28.59; Skin - Sun Exposed (Lower leg): 28.48; Pituitary: 28.43; Bladder: 26.95; Breast - Mammary Tissue: 26.51; Artery - Tibial: 26.31; Spleen: 26.30; Lung: 26.19; Adipose - Subcutaneous: 25.83; Small Intestine - Terminal Ileum: 24.34; Esophagus - Gastroesophageal Junction: 22.89; Artery - Aorta: 22.09; Cells - EBV-transformed lymphocytes: 21.30; Artery - Coronary: 21.21; Colon - Transverse: 21.18; Esophagus - Muscularis: 20.43; Adipose - Visceral (Omentum): 19.90; Minor Salivary Gland: 19.89; Cells - Transformed fibroblasts: 18.24; Kidney - Cortex: 16.55; Stomach: 16.48; Esophagus - Mucosa: 16.12; Brain - Spinal cord (cervical c-1): 13.34; Adrenal Gland: 12.04; Pancreas: 11.33; Brain - Frontal Cortex (BA9): 9.91; Brain - Cortex: 9.90; Heart - Atrial Appendage: 9.89; Brain - Nucleus accumbens (basal ganglia): 9.88; Brain - Hypothalamus: 9.67; Brain - Caudate (basal ganglia): 9.45; Liver: 9.38; Muscle - Skeletal: 8.96; Brain - Substantia nigra: 8.68; Brain - Hippocampus: 8.36; Brain - Putamen (basal ganglia): 8.15; Brain - Amygdala: 7.86; Brain - Anterior cingulate cortex (BA24): 7.79; Heart - Left Ventricle: 5.88; Whole Blood: 4.27; MAGSDAEWVTIANNLLFKCHIHLRIHELQDCDANVFIALYQSILGEKVPDLIVIPRSQEDDAHNVQAVIDSLALDYLQVSLSHITGENIVKGDKESIKNLLEIFDGLLEYLTERISETSHEKSETEQYFKESDRGERLEEPESTKESKSSWKRVSFGRCSLSSEMLGPSWDGDEAESTGEIIRLGDTAHTFSLRSNGAQCPNEMLSKKALASPSSKSHEDMLYPPSVLSKSRTSFVEDTETLSVSGIPNARKLGEPIRAAIPLHPPYHPSEPRAPCPIGKEYLHSSHCSPAVNSTGEHTEFSGDLDDGLFLISKLPKGSKWEVYPAQVQGPRTRKPPKGKRNENRATASSCNSPFPQRPRKRLTEQELHDVSEKLSQRLSELDWMLKSALGDRIKEKTDHKEENTGNEEVEDGTEETLSQHSDGIVEYGPKKSRPGLSMRRKPPYRSHSLSPSPVNKHKQFHLERKRQRKPRETDVRQFQAQAFTEAFERELRRHKVQENIGPLRIHEKEEETEKIYRGEAVRKGTPECSQPWKIYSRKTTTQSLRGGLPKPNKAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQQIAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIRRQRLTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLNIQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQAQTLHKVKRELRSKMEKEIQQLQDMITQNDDDVFFRELEAERFRSRLQLASFQYSKSPSL LRRC37A3 Leucine-rich repeat-containing protein 37A3 L37A3_HUMAN (O60309-1) GO:0098772 (0.29) ! molecular function regulator; GO:0004860 (0.28) ! protein kinase inhibitor activity; GO:0097367 (0.17) ! carbohydrate derivative binding; GO:0005102 (0.17) ! receptor binding; GO:0004872 (0.16) ! receptor activity; GO:0005539 (0.15) ! glycosaminoglycan binding; GO:0008201 (0.14) ! heparin binding; GO:0048495 (0.13) ! Roundabout binding; GO:0004871 (0.12) ! signal transducer activity; GO:0038023 (0.11) ! signaling receptor activity; GO:0003824 (0.10) ! catalytic activity; GO:0003676 (0.10) ! nucleic acid binding; GO:0004888 (0.08) ! transmembrane signaling receptor activity; GO:0003723 (0.07) ! RNA binding; GO:0004930 (0.06) ! G-protein coupled receptor activity; GO:0016740 (0.05) ! transferase activity; GO:0005198 (0.05) ! structural molecule activity; GO:0032403 (0.04) ! protein complex binding; GO:0004672 (0.04) ! protein kinase activity; GO:0044822 (0.03) ! poly(A) RNA binding; GO:0019899 (0.03) ! enzyme binding; GO:0016787 (0.03) ! hydrolase activity; GO:0005201 (0.03) ! extracellular matrix structural constituent; GO:0004674 (0.03) ! protein serine/threonine kinase activity; GO:0003779 (0.03) ! actin binding; GO:0003725 (0.03) ! double-stranded RNA binding; GO:0042802 (0.02) ! identical protein binding; GO:0042277 (0.02) ! peptide binding; GO:0019838 (0.02) ! growth factor binding; GO:0008528 (0.02) ! G-protein coupled peptide receptor activity; GO:0008289 (0.02) ! lipid binding; GO:0008190 (0.02) ! eukaryotic initiation factor 4E binding; GO:0005518 (0.02) ! collagen binding; GO:0005154 (0.02) ! epidermal growth factor receptor binding; GO:0003677 (0.02) ! DNA binding; GO:0097493 (0.01) ! structural molecule activity conferring elasticity; GO:0071723 (0.01) ! lipopeptide binding; GO:0070052 (0.01) ! collagen V binding; GO:0051371 (0.01) ! muscle alpha-actinin binding; GO:0051015 (0.01) ! actin filament binding; GO:0050840 (0.01) ! extracellular matrix binding; GO:0050839 (0.01) ! cell adhesion molecule binding; GO:0050431 (0.01) ! transforming growth factor beta binding; GO:0044212 (0.01) ! transcription regulatory region DNA binding; GO:0043565 (0.01) ! sequence-specific DNA binding; GO:0043394 (0.01) ! proteoglycan binding; GO:0042803 (0.01) ! protein homodimerization activity; GO:0035663 (0.01) ! Toll-like receptor 2 binding; GO:0035197 (0.01) ! siRNA binding; GO:0019904 (0.01) ! protein domain specific binding; GO:0019902 (0.01) ! phosphatase binding; GO:0019901 (0.01) ! protein kinase binding; GO:0017016 (0.01) ! Ras GTPase binding; GO:0016887 (0.01) ! ATPase activity; GO:0016811 (0.01) ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0016788 (0.01) ! hydrolase activity, acting on ester bonds; GO:0016500 (0.01) ! protein-hormone receptor activity; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008134 (0.01) ! transcription factor binding; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005540 (0.01) ! hyaluronic acid binding; GO:0005520 (0.01) ! insulin-like growth factor binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005216 (0.01) ! ion channel activity; GO:0005149 (0.01) ! interleukin-1 receptor binding; GO:0005030 (0.01) ! neurotrophin receptor activity; GO:0004842 (0.01) ! ubiquitin-protein transferase activity; GO:0004826 (0.01) ! phenylalanine-tRNA ligase activity; GO:0004252 (0.01) ! serine-type endopeptidase activity; GO:0003727 (0.01) ! single-stranded RNA binding; GO:0003713 (0.01) ! transcription coactivator activity; GO:0003700 (0.01) ! transcription factor activity, sequence-specific DNA binding; GO:0003682 (0.01) ! chromatin binding; GO:0001875 (0.01) ! lipopolysaccharide receptor activity; GO:0001530 (0.01) ! lipopolysaccharide binding; GO:0000166 (0.01) ! nucleotide binding GO:0065007 (0.62) ! biological regulation; GO:0050789 (0.60) ! regulation of biological process; GO:0050794 (0.59) ! regulation of cellular process; GO:0009987 (0.59) ! cellular process; GO:0044699 (0.54) ! single-organism process; GO:0044763 (0.48) ! single-organism cellular process; GO:0007165 (0.47) ! signal transduction; GO:0032502 (0.45) ! developmental process; GO:0044767 (0.44) ! single-organism developmental process; GO:0016043 (0.35) ! cellular component organization; GO:0048583 (0.34) ! regulation of response to stimulus; GO:0007166 (0.32) ! cell surface receptor signaling pathway; GO:0009653 (0.31) ! anatomical structure morphogenesis; GO:0019222 (0.30) ! regulation of metabolic process; GO:0048869 (0.29) ! cellular developmental process; GO:0048519 (0.29) ! negative regulation of biological process; GO:0031323 (0.29) ! regulation of cellular metabolic process; GO:0080090 (0.28) ! regulation of primary metabolic process; GO:0060255 (0.28) ! regulation of macromolecule metabolic process; GO:0048523 (0.28) ! negative regulation of cellular process; GO:0030030 (0.27) ! cell projection organization; GO:0065009 (0.26) ! regulation of molecular function; GO:0032989 (0.26) ! cellular component morphogenesis; GO:0009966 (0.26) ! regulation of signal transduction; GO:0007409 (0.25) ! axonogenesis; GO:0051246 (0.24) ! regulation of protein metabolic process; GO:0050790 (0.24) ! regulation of catalytic activity; GO:0019220 (0.24) ! regulation of phosphate metabolic process; GO:1902531 (0.23) ! regulation of intracellular signal transduction; GO:0031324 (0.23) ! negative regulation of cellular metabolic process; GO:0010605 (0.23) ! negative regulation of macromolecule metabolic process; GO:0009968 (0.23) ! negative regulation of signal transduction; GO:0001932 (0.23) ! regulation of protein phosphorylation; GO:0045936 (0.22) ! negative regulation of phosphate metabolic process; GO:0045859 (0.22) ! regulation of protein kinase activity; GO:0044092 (0.22) ! negative regulation of molecular function; GO:0031400 (0.22) ! negative regulation of protein modification process; GO:0046426 (0.21) ! negative regulation of JAK-STAT cascade; GO:0019221 (0.21) ! cytokine-mediated signaling pathway; GO:0006469 (0.21) ! negative regulation of protein kinase activity; GO:0048518 (0.19) ! positive regulation of biological process; GO:0051239 (0.17) ! regulation of multicellular organismal process; GO:0051128 (0.16) ! regulation of cellular component organization; GO:0050896 (0.15) ! response to stimulus; GO:2000026 (0.14) ! regulation of multicellular organismal development; GO:0051960 (0.12) ! regulation of nervous system development; GO:0045595 (0.12) ! regulation of cell differentiation; GO:0048856 (0.11) ! anatomical structure development; GO:0048584 (0.11) ! positive regulation of response to stimulus; GO:0048522 (0.11) ! positive regulation of cellular process; GO:0040007 (0.11) ! growth; GO:0010975 (0.11) ! regulation of neuron projection development; GO:0010769 (0.11) ! regulation of cell morphogenesis involved in differentiation; GO:0006950 (0.11) ! response to stress; GO:0002376 (0.11) ! immune system process; GO:1990138 (0.10) ! neuron projection extension; GO:0050770 (0.10) ! regulation of axonogenesis; GO:0035385 (0.10) ! Roundabout signaling pathway; GO:0032501 (0.10) ! multicellular organismal process; GO:0009605 (0.10) ! response to external stimulus; GO:0002682 (0.10) ! regulation of immune system process; GO:0071704 (0.09) ! organic substance metabolic process; GO:0048846 (0.09) ! axon extension involved in axon guidance; GO:0045088 (0.09) ! regulation of innate immune response; GO:0044237 (0.09) ! cellular metabolic process; GO:0043207 (0.09) ! response to external biotic stimulus; GO:0006952 (0.09) ! defense response; GO:0002684 (0.09) ! positive regulation of immune system process; GO:0051704 (0.08) ! multi-organism process; GO:0044238 (0.08) ! primary metabolic process; GO:0043170 (0.08) ! macromolecule metabolic process; GO:0002764 (0.08) ! immune response-regulating signaling pathway; GO:0002218 (0.08) ! activation of innate immune response; GO:0098542 (0.07) ! defense response to other organism; GO:0044260 (0.07) ! cellular macromolecule metabolic process; GO:0002224 (0.07) ! toll-like receptor signaling pathway; GO:0051171 (0.06) ! regulation of nitrogen compound metabolic process; GO:0044707 (0.06) ! single-multicellular organism process; GO:0031326 (0.06) ! regulation of cellular biosynthetic process; GO:0031325 (0.06) ! positive regulation of cellular metabolic process; GO:0006928 (0.06) ! movement of cell or subcellular component; GO:0065008 (0.05) ! regulation of biological quality; GO:0051179 (0.05) ! localization; GO:0032879 (0.05) ! regulation of localization; GO:0031328 (0.05) ! positive regulation of cellular biosynthetic process; GO:0022414 (0.05) ! reproductive process; GO:0019538 (0.05) ! protein metabolic process; GO:0019219 (0.05) ! regulation of nucleobase-containing compound metabolic process; GO:0010033 (0.05) ! response to organic substance; GO:0006996 (0.05) ! organelle organization; GO:2000112 (0.04) ! regulation of cellular macromolecule biosynthetic process; GO:1901360 (0.04) ! organic cyclic compound metabolic process; GO:0051716 (0.04) ! cellular response to stimulus; GO:0051252 (0.04) ! regulation of RNA metabolic process; GO:0051240 (0.04) ! positive regulation of multicellular organismal process; GO:0051173 (0.04) ! positive regulation of nitrogen compound metabolic process; GO:0048513 (0.04) ! animal organ development; GO:0046483 (0.04) ! heterocycle metabolic process; GO:0044702 (0.04) ! single organism reproductive process; GO:0044093 (0.04) ! positive regulation of molecular function; GO:0044087 (0.04) ! regulation of cellular component biogenesis; GO:0043933 (0.04) ! macromolecular complex subunit organization; GO:0034641 (0.04) ! cellular nitrogen compound metabolic process; GO:0023056 (0.04) ! positive regulation of signaling; GO:0022607 (0.04) ! cellular component assembly; GO:0010647 (0.04) ! positive regulation of cell communication; GO:0010604 (0.04) ! positive regulation of macromolecule metabolic process; GO:0010468 (0.04) ! regulation of gene expression; GO:0007411 (0.04) ! axon guidance; GO:0007186 (0.04) ! G-protein coupled receptor signaling pathway; GO:0006810 (0.04) ! transport; GO:0006725 (0.04) ! cellular aromatic compound metabolic process; GO:0006464 (0.04) ! cellular protein modification process; GO:0003008 (0.04) ! system process; GO:1902589 (0.03) ! single-organism organelle organization; GO:0065003 (0.03) ! macromolecular complex assembly; GO:0051641 (0.03) ! cellular localization; GO:0051241 (0.03) ! negative regulation of multicellular organismal process; GO:0051130 (0.03) ! positive regulation of cellular component organization; GO:0051049 (0.03) ! regulation of transport; GO:0050877 (0.03) ! neurological system process; GO:0048731 (0.03) ! system development; GO:0045935 (0.03) ! positive regulation of nucleobase-containing compound metabolic process; GO:0044419 (0.03) ! interspecies interaction between organisms; GO:0042742 (0.03) ! defense response to bacterium; GO:0040008 (0.03) ! regulation of growth; GO:0033043 (0.03) ! regulation of organelle organization; GO:0016477 (0.03) ! cell migration; GO:0016070 (0.03) ! RNA metabolic process; GO:0010557 (0.03) ! positive regulation of macromolecule biosynthetic process; GO:0009967 (0.03) ! positive regulation of signal transduction; GO:0008104 (0.03) ! protein localization; GO:0007188 (0.03) ! adenylate cyclase-modulating G-protein coupled receptor signaling pathway; GO:0007155 (0.03) ! cell adhesion; GO:0007010 (0.03) ! cytoskeleton organization; GO:0006955 (0.03) ! immune response; GO:0006954 (0.03) ! inflammatory response; GO:0006355 (0.03) ! regulation of transcription, DNA-templated; GO:0003006 (0.03) ! developmental process involved in reproduction; GO:0002237 (0.03) ! response to molecule of bacterial origin; GO:1903047 (0.02) ! mitotic cell cycle process; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:1901698 (0.02) ! response to nitrogen compound; GO:1901564 (0.02) ! organonitrogen compound metabolic process; GO:0090066 (0.02) ! regulation of anatomical structure size; GO:0071822 (0.02) ! protein complex subunit organization; GO:0071310 (0.02) ! cellular response to organic substance; GO:0071219 (0.02) ! cellular response to molecule of bacterial origin; GO:0070925 (0.02) ! organelle assembly; GO:0051962 (0.02) ! positive regulation of nervous system development; GO:0051607 (0.02) ! defense response to virus; GO:0051606 (0.02) ! detection of stimulus; GO:0051247 (0.02) ! positive regulation of protein metabolic process; GO:0051129 (0.02) ! negative regulation of cellular component organization; GO:0051093 (0.02) ! negative regulation of developmental process; GO:0051050 (0.02) ! positive regulation of transport; GO:0048729 (0.02) ! tissue morphogenesis; GO:0048646 (0.02) ! anatomical structure formation involved in morphogenesis; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0048468 (0.02) ! cell development; GO:0046907 (0.02) ! intracellular transport; GO:0045944 (0.02) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045937 (0.02) ! positive regulation of phosphate metabolic process; GO:0045087 (0.02) ! innate immune response; GO:0044765 (0.02) ! single-organism transport; GO:0044710 (0.02) ! single-organism metabolic process; GO:0044089 (0.02) ! positive regulation of cellular component biogenesis; GO:0043085 (0.02) ! positive regulation of catalytic activity; GO:0035556 (0.02) ! intracellular signal transduction; GO:0034622 (0.02) ! cellular macromolecular complex assembly; GO:0033993 (0.02) ! response to lipid; GO:0032493 (0.02) ! response to bacterial lipoprotein; GO:0032101 (0.02) ! regulation of response to external stimulus; GO:0031032 (0.02) ! actomyosin structure organization; GO:0030308 (0.02) ! negative regulation of cell growth; GO:0030154 (0.02) ! cell differentiation; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0016071 (0.02) ! mRNA metabolic process; GO:0015031 (0.02) ! protein transport; GO:0010941 (0.02) ! regulation of cell death; GO:0010629 (0.02) ! negative regulation of gene expression; GO:0009888 (0.02) ! tissue development; GO:0009886 (0.02) ! post-embryonic morphogenesis; GO:0007610 (0.02) ! behavior; GO:0007600 (0.02) ! sensory perception; GO:0007275 (0.02) ! multicellular organism development; GO:0007267 (0.02) ! cell-cell signaling; GO:0007189 (0.02) ! adenylate cyclase-activating G-protein coupled receptor signaling pathway; GO:0006468 (0.02) ! protein phosphorylation; GO:0001817 (0.02) ! regulation of cytokine production; GO:0001775 (0.02) ! cell activation; GO:2000021 (0.01) ! regulation of ion homeostasis; GO:1904064 (0.01) ! positive regulation of cation transmembrane transport; GO:1903827 (0.01) ! regulation of cellular protein localization; GO:1902580 (0.01) ! single-organism cellular localization; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:1901565 (0.01) ! organonitrogen compound catabolic process; GO:1901361 (0.01) ! organic cyclic compound catabolic process; GO:1901135 (0.01) ! carbohydrate derivative metabolic process; GO:1900227 (0.01) ! positive regulation of NLRP3 inflammasome complex assembly; GO:0090287 (0.01) ! regulation of cellular response to growth factor stimulus; GO:0090263 (0.01) ! positive regulation of canonical Wnt signaling pathway; GO:0080135 (0.01) ! regulation of cellular response to stress; GO:0072593 (0.01) ! reactive oxygen species metabolic process; GO:0071727 (0.01) ! cellular response to triacyl bacterial lipopeptide; GO:0071726 (0.01) ! cellular response to diacyl bacterial lipopeptide; GO:0071396 (0.01) ! cellular response to lipid; GO:0070372 (0.01) ! regulation of ERK1 and ERK2 cascade; GO:0061564 (0.01) ! axon development; GO:0061024 (0.01) ! membrane organization; GO:0060026 (0.01) ! convergent extension; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051965 (0.01) ! positive regulation of synapse assembly; GO:0051705 (0.01) ! multi-organism behavior; GO:0051646 (0.01) ! mitochondrion localization; GO:0051493 (0.01) ! regulation of cytoskeleton organization; GO:0051091 (0.01) ! positive regulation of sequence-specific DNA binding transcription factor activity; GO:0051056 (0.01) ! regulation of small GTPase mediated signal transduction; GO:0050920 (0.01) ! regulation of chemotaxis; GO:0050919 (0.01) ! negative chemotaxis; GO:0050829 (0.01) ! defense response to Gram-negative bacterium; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0050772 (0.01) ! positive regulation of axonogenesis; GO:0050709 (0.01) ! negative regulation of protein secretion; GO:0050702 (0.01) ! interleukin-1 beta secretion; GO:0048739 (0.01) ! cardiac muscle fiber development; GO:0048678 (0.01) ! response to axon injury; GO:0048608 (0.01) ! reproductive structure development; GO:0048569 (0.01) ! post-embryonic organ development; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046700 (0.01) ! heterocycle catabolic process; GO:0046331 (0.01) ! lateral inhibition; GO:0045927 (0.01) ! positive regulation of growth; GO:0045359 (0.01) ! positive regulation of interferon-beta biosynthetic process; GO:0045356 (0.01) ! positive regulation of interferon-alpha biosynthetic process; GO:0045214 (0.01) ! sarcomere organization; GO:0045078 (0.01) ! positive regulation of interferon-gamma biosynthetic process; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0044719 (0.01) ! regulation of imaginal disc-derived wing size; GO:0044712 (0.01) ! single-organism catabolic process; GO:0044708 (0.01) ! single-organism behavior; GO:0044270 (0.01) ! cellular nitrogen compound catabolic process; GO:0043902 (0.01) ! positive regulation of multi-organism process; GO:0043410 (0.01) ! positive regulation of MAPK cascade; GO:0043331 (0.01) ! response to dsRNA; GO:0043123 (0.01) ! positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043087 (0.01) ! regulation of GTPase activity; GO:0043069 (0.01) ! negative regulation of programmed cell death; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0042592 (0.01) ! homeostatic process; GO:0042116 (0.01) ! macrophage activation; GO:0042058 (0.01) ! regulation of epidermal growth factor receptor signaling pathway; GO:0040023 (0.01) ! establishment of nucleus localization; GO:0040017 (0.01) ! positive regulation of locomotion; GO:0040005 (0.01) ! chitin-based cuticle attachment to epithelium; GO:0035147 (0.01) ! branch fusion, open tracheal system; GO:0034660 (0.01) ! ncRNA metabolic process; GO:0034654 (0.01) ! nucleobase-containing compound biosynthetic process; GO:0034645 (0.01) ! cellular macromolecule biosynthetic process; GO:0034248 (0.01) ! regulation of cellular amide metabolic process; GO:0034121 (0.01) ! regulation of toll-like receptor signaling pathway; GO:0034063 (0.01) ! stress granule assembly; GO:0033554 (0.01) ! cellular response to stress; GO:0033365 (0.01) ! protein localization to organelle; GO:0032757 (0.01) ! positive regulation of interleukin-8 production; GO:0032755 (0.01) ! positive regulation of interleukin-6 production; GO:0032497 (0.01) ! detection of lipopolysaccharide; GO:0032414 (0.01) ! positive regulation of ion transmembrane transporter activity; GO:0032386 (0.01) ! regulation of intracellular transport; GO:0032103 (0.01) ! positive regulation of response to external stimulus; GO:0032102 (0.01) ! negative regulation of response to external stimulus; GO:0031290 (0.01) ! retinal ganglion cell axon guidance; GO:0030517 (0.01) ! negative regulation of axon extension; GO:0030336 (0.01) ! negative regulation of cell migration; GO:0030241 (0.01) ! skeletal muscle myosin thick filament assembly; GO:0030240 (0.01) ! skeletal muscle thin filament assembly; GO:0030198 (0.01) ! extracellular matrix organization; GO:0030155 (0.01) ! regulation of cell adhesion; GO:0030100 (0.01) ! regulation of endocytosis; GO:0022602 (0.01) ! ovulation cycle process; GO:0021952 (0.01) ! central nervous system projection neuron axonogenesis; GO:0019752 (0.01) ! carboxylic acid metabolic process; GO:0019730 (0.01) ! antimicrobial humoral response; GO:0019439 (0.01) ! aromatic compound catabolic process; GO:0019233 (0.01) ! sensory perception of pain; GO:0018205 (0.01) ! peptidyl-lysine modification; GO:0016570 (0.01) ! histone modification; GO:0016482 (0.01) ! cytosolic transport; GO:0016337 (0.01) ! single organismal cell-cell adhesion; GO:0012501 (0.01) ! programmed cell death; GO:0010959 (0.01) ! regulation of metal ion transport; GO:0010638 (0.01) ! positive regulation of organelle organization; GO:0010631 (0.01) ! epithelial cell migration; GO:0010603 (0.01) ! regulation of cytoplasmic mRNA processing body assembly; GO:0010243 (0.01) ! response to organonitrogen compound; GO:0009887 (0.01) ! organ morphogenesis; GO:0009792 (0.01) ! embryo development ending in birth or egg hatching; GO:0009755 (0.01) ! hormone-mediated signaling pathway; GO:0009725 (0.01) ! response to hormone; GO:0009612 (0.01) ! response to mechanical stimulus; GO:0009057 (0.01) ! macromolecule catabolic process; GO:0008362 (0.01) ! chitin-based embryonic cuticle biosynthetic process; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008045 (0.01) ! motor neuron axon guidance; GO:0008037 (0.01) ! cell recognition; GO:0007522 (0.01) ! visceral muscle development; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007498 (0.01) ! mesoderm development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007475 (0.01) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.01) ! open tracheal system development; GO:0007420 (0.01) ! brain development; GO:0007417 (0.01) ! central nervous system development; GO:0007416 (0.01) ! synapse assembly; GO:0007389 (0.01) ! pattern specification process; GO:0007346 (0.01) ! regulation of mitotic cell cycle; GO:0007283 (0.01) ! spermatogenesis; GO:0007190 (0.01) ! activation of adenylate cyclase activity; GO:0007169 (0.01) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007156 (0.01) ! homophilic cell adhesion via plasma membrane adhesion molecules; GO:0006941 (0.01) ! striated muscle contraction; GO:0006897 (0.01) ! endocytosis; GO:0006811 (0.01) ! ion transport; GO:0006790 (0.01) ! sulfur compound metabolic process; GO:0006259 (0.01) ! DNA metabolic process; GO:0003013 (0.01) ! circulatory system process; GO:0002833 (0.01) ! positive regulation of response to biotic stimulus; GO:0002761 (0.01) ! regulation of myeloid leukocyte differentiation; GO:0002700 (0.01) ! regulation of production of molecular mediator of immune response; GO:0002683 (0.01) ! negative regulation of immune system process; GO:0001818 (0.01) ! negative regulation of cytokine production; GO:0001654 (0.01) ! eye development; GO:0001501 (0.01) ! skeletal system development; GO:0000398 (0.01) ! mRNA splicing, via spliceosome; GO:0000281 (0.01) ! mitotic cytokinesis; GO:0000226 (0.01) ! microtubule cytoskeleton organization; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter GO:0044464 (0.77) ! cell part; GO:0044424 (0.57) ! intracellular part; GO:0005737 (0.38) ! cytoplasm; GO:0044421 (0.26) ! extracellular region part; GO:0044425 (0.20) ! membrane part; GO:0031012 (0.20) ! extracellular matrix; GO:0043226 (0.19) ! organelle; GO:0005615 (0.19) ! extracellular space; GO:0005578 (0.18) ! proteinaceous extracellular matrix; GO:0044459 (0.16) ! plasma membrane part; GO:0031224 (0.16) ! intrinsic component of membrane; GO:0016020 (0.16) ! membrane; GO:0043229 (0.15) ! intracellular organelle; GO:0043227 (0.15) ! membrane-bounded organelle; GO:0044444 (0.14) ! cytoplasmic part; GO:0031226 (0.14) ! intrinsic component of plasma membrane; GO:0016021 (0.14) ! integral component of membrane; GO:0032991 (0.13) ! macromolecular complex; GO:0005887 (0.13) ! integral component of plasma membrane; GO:0044422 (0.12) ! organelle part; GO:0043231 (0.12) ! intracellular membrane-bounded organelle; GO:0044446 (0.11) ! intracellular organelle part; GO:0005886 (0.11) ! plasma membrane; GO:0043234 (0.10) ! protein complex; GO:0005634 (0.07) ! nucleus; GO:0044428 (0.06) ! nuclear part; GO:0031988 (0.06) ! membrane-bounded vesicle; GO:0070062 (0.04) ! extracellular exosome; GO:0043232 (0.04) ! intracellular non-membrane-bounded organelle; GO:0005654 (0.04) ! nucleoplasm; GO:0098796 (0.03) ! membrane protein complex; GO:0097458 (0.03) ! neuron part; GO:0044430 (0.03) ! cytoskeletal part; GO:1902494 (0.02) ! catalytic complex; GO:0098797 (0.02) ! plasma membrane protein complex; GO:0098590 (0.02) ! plasma membrane region; GO:0098588 (0.02) ! bounding membrane of organelle; GO:0045121 (0.02) ! membrane raft; GO:0044463 (0.02) ! cell projection part; GO:0044451 (0.02) ! nucleoplasm part; GO:0044431 (0.02) ! Golgi apparatus part; GO:0043235 (0.02) ! receptor complex; GO:0042995 (0.02) ! cell projection; GO:0031410 (0.02) ! cytoplasmic vesicle; GO:0030529 (0.02) ! intracellular ribonucleoprotein complex; GO:0030054 (0.02) ! cell junction; GO:0030018 (0.02) ! Z disc; GO:0009986 (0.02) ! cell surface; GO:0005829 (0.02) ! cytosol; GO:0005794 (0.02) ! Golgi apparatus; GO:0005783 (0.02) ! endoplasmic reticulum; GO:0005576 (0.02) ! extracellular region; GO:0098791 (0.01) ! Golgi subcompartment; GO:0097060 (0.01) ! synaptic membrane; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0046696 (0.01) ! lipopolysaccharide receptor complex; GO:0045202 (0.01) ! synapse; GO:0044441 (0.01) ! ciliary part; GO:0044440 (0.01) ! endosomal part; GO:0044432 (0.01) ! endoplasmic reticulum part; GO:0044427 (0.01) ! chromosomal part; GO:0044297 (0.01) ! cell body; GO:0044295 (0.01) ! axonal growth cone; GO:0042567 (0.01) ! insulin-like growth factor ternary complex; GO:0035097 (0.01) ! histone methyltransferase complex; GO:0034702 (0.01) ! ion channel complex; GO:0031430 (0.01) ! M band; GO:0031225 (0.01) ! anchored component of membrane; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030134 (0.01) ! ER to Golgi transport vesicle; GO:0016607 (0.01) ! nuclear speck; GO:0016323 (0.01) ! basolateral plasma membrane; GO:0015629 (0.01) ! actin cytoskeleton; GO:0010494 (0.01) ! cytoplasmic stress granule; GO:0009897 (0.01) ! external side of plasma membrane; GO:0009328 (0.01) ! phenylalanine-tRNA ligase complex; GO:0008305 (0.01) ! integrin complex; GO:0005924 (0.01) ! cell-substrate adherens junction; GO:0005913 (0.01) ! cell-cell adherens junction; GO:0005884 (0.01) ! actin filament; GO:0005865 (0.01) ! striated muscle thin filament; GO:0005859 (0.01) ! muscle myosin complex; GO:0005815 (0.01) ! microtubule organizing center; GO:0005796 (0.01) ! Golgi lumen; GO:0005774 (0.01) ! vacuolar membrane; GO:0005768 (0.01) ! endosome; GO:0005764 (0.01) ! lysosome; GO:0005739 (0.01) ! mitochondrion; GO:0005694 (0.01) ! chromosome; GO:0005640 (0.01) ! nuclear outer membrane; GO:0005635 (0.01) ! nuclear envelope; GO:0005622 (0.01) ! intracellular; GO:0000164 (0.01) ! protein phosphatase type 1 complex; GO:0000139 (0.01) ! Golgi membrane GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 64854312-64919480 (17q24.1) High: testis (elongated or late spermatids; round or early spermatids);Low: testis (pachytene spermatocytes; preleptotene spermatocytes); Testis: 20.21; Pituitary: 14.32; Thyroid: 12.72; Brain - Cerebellar Hemisphere: 8.97; Brain - Cerebellum: 8.47; Brain - Hypothalamus: 5.96; Prostate: 5.39; Ovary: 4.94; Brain - Nucleus accumbens (basal ganglia): 4.81; Nerve - Tibial: 4.79; Brain - Cortex: 4.58; Brain - Frontal Cortex (BA9): 4.53; Fallopian Tube: 3.95; Kidney - Cortex: 3.85; Brain - Anterior cingulate cortex (BA24): 3.71; Brain - Caudate (basal ganglia): 3.62; Uterus: 3.45; Cervix - Endocervix: 3.26; Brain - Hippocampus: 3.06; Brain - Amygdala: 3.01; Artery - Coronary: 2.98; Vagina: 2.96; Brain - Substantia nigra: 2.85; Breast - Mammary Tissue: 2.77; Brain - Putamen (basal ganglia): 2.77; Artery - Aorta: 2.77; Lung: 2.71; Artery - Tibial: 2.68; Brain - Spinal cord (cervical c-1): 2.59; Cervix - Ectocervix: 2.50; Spleen: 2.39; Adipose - Subcutaneous: 2.33; Bladder: 2.09; Esophagus - Gastroesophageal Junction: 2.08; Colon - Sigmoid: 2.04; Skin - Sun Exposed (Lower leg): 1.98; Adipose - Visceral (Omentum): 1.87; Cells - Transformed fibroblasts: 1.75; Skin - Not Sun Exposed (Suprapubic): 1.72; Esophagus - Muscularis: 1.72; Adrenal Gland: 1.65; Minor Salivary Gland: 1.53; Small Intestine - Terminal Ileum: 1.41; Esophagus - Mucosa: 1.39; Colon - Transverse: 1.24; Stomach: 0.90; Heart - Atrial Appendage: 0.90; Pancreas: 0.86; Liver: 0.83; Whole Blood: 0.60; Muscle - Skeletal: 0.46; Cells - EBV-transformed lymphocytes: 0.46; Heart - Left Ventricle: 0.38; MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP C17orf58 UPF0450 protein C17orf58 CQ058_HUMAN (Q2M2W7-1) GO:0046872 (0.13) ! metal ion binding; GO:0008191 (0.13) ! metalloendopeptidase inhibitor activity; GO:0004252 (0.13) ! serine-type endopeptidase activity; GO:0002020 (0.13) ! protease binding; GO:0048037 (0.07) ! cofactor binding; GO:0031715 (0.07) ! C5L2 anaphylatoxin chemotactic receptor binding; GO:0016504 (0.07) ! peptidase activator activity; GO:0008289 (0.07) ! lipid binding; GO:0008201 (0.07) ! heparin binding; GO:0008083 (0.07) ! growth factor activity; GO:0005518 (0.07) ! collagen binding; GO:0005125 (0.07) ! cytokine activity; GO:0001849 (0.07) ! complement component C1q binding GO:0052548 (0.37) ! regulation of endopeptidase activity; GO:0010466 (0.37) ! negative regulation of peptidase activity GO:0044464 (0.80) ! cell part; GO:0043227 (0.80) ! membrane-bounded organelle; GO:0005615 (0.67) ! extracellular space; GO:0005576 (0.67) ! extracellular region; GO:0031988 (0.60) ! membrane-bounded vesicle; GO:0070062 (0.53) ! extracellular exosome; GO:0044424 (0.47) ! intracellular part; GO:0044446 (0.33) ! intracellular organelle part; GO:0043231 (0.33) ! intracellular membrane-bounded organelle; GO:0016020 (0.33) ! membrane; GO:0044444 (0.27) ! cytoplasmic part; GO:0044425 (0.27) ! membrane part; GO:0032991 (0.27) ! macromolecular complex; GO:0031012 (0.27) ! extracellular matrix; GO:0005886 (0.27) ! plasma membrane; GO:0005634 (0.27) ! nucleus; GO:0005737 (0.20) ! cytoplasm; GO:0005578 (0.20) ! proteinaceous extracellular matrix; GO:0072562 (0.13) ! blood microparticle; GO:0044428 (0.13) ! nuclear part; GO:0042995 (0.13) ! cell projection; GO:0034774 (0.13) ! secretory granule lumen; GO:0005604 (0.13) ! basement membrane; GO:0005579 (0.13) ! membrane attack complex; GO:0000785 (0.13) ! chromatin; GO:1990879 (0.07) ! CST complex; GO:0043025 (0.07) ! neuronal cell body; GO:0043005 (0.07) ! neuron projection; GO:0031143 (0.07) ! pseudopodium; GO:0031093 (0.07) ! platelet alpha granule lumen; GO:0031090 (0.07) ! organelle membrane; GO:0031089 (0.07) ! platelet dense granule lumen; GO:0030426 (0.07) ! growth cone; GO:0016023 (0.07) ! cytoplasmic, membrane-bounded vesicle; GO:0016021 (0.07) ! integral component of membrane; GO:0009986 (0.07) ! cell surface; GO:0005923 (0.07) ! bicellular tight junction; GO:0005905 (0.07) ! clathrin-coated pit; GO:0005829 (0.07) ! cytosol; GO:0005789 (0.07) ! endoplasmic reticulum membrane; GO:0005783 (0.07) ! endoplasmic reticulum; GO:0005724 (0.07) ! nuclear telomeric heterochromatin; GO:0005694 (0.07) ! chromosome; GO:0005654 (0.07) ! nucleoplasm; GO:0005622 (0.07) ! intracellular; GO:0000784 (0.07) ! nuclear chromosome, telomeric region 2 67991101-67996431 (17q24.2) Cervix - Endocervix: 27.79; Cervix - Ectocervix: 25.84; Brain - Cerebellar Hemisphere: 20.25; Uterus: 18.65; Vagina: 17.90; Breast - Mammary Tissue: 16.43; Brain - Cerebellum: 15.99; Adipose - Subcutaneous: 14.13; Cells - Transformed fibroblasts: 13.85; Brain - Frontal Cortex (BA9): 12.89; Fallopian Tube: 12.55; Adipose - Visceral (Omentum): 12.51; Bladder: 12.12; Thyroid: 11.74; Brain - Anterior cingulate cortex (BA24): 10.80; Brain - Cortex: 10.39; Artery - Coronary: 10.17; Brain - Nucleus accumbens (basal ganglia): 9.74; Adrenal Gland: 9.63; Prostate: 9.51; Brain - Amygdala: 9.28; Nerve - Tibial: 9.05; Brain - Caudate (basal ganglia): 9.01; Esophagus - Gastroesophageal Junction: 8.91; Esophagus - Mucosa: 8.58; Pituitary: 8.50; Testis: 8.40; Esophagus - Muscularis: 8.35; Brain - Hypothalamus: 8.05; Ovary: 7.96; Artery - Aorta: 7.78; Small Intestine - Terminal Ileum: 7.71; Minor Salivary Gland: 7.45; Colon - Transverse: 7.35; Brain - Hippocampus: 7.30; Brain - Putamen (basal ganglia): 7.27; Brain - Substantia nigra: 7.26; Brain - Spinal cord (cervical c-1): 7.18; Lung: 7.14; Stomach: 6.96; Colon - Sigmoid: 6.90; Heart - Atrial Appendage: 6.82; Spleen: 6.64; Skin - Sun Exposed (Lower leg): 6.44; Liver: 6.31; Skin - Not Sun Exposed (Suprapubic): 6.16; Kidney - Cortex: 6.05; Artery - Tibial: 5.06; Pancreas: 4.76; Cells - EBV-transformed lymphocytes: 4.39; Heart - Left Ventricle: 4.00; Muscle - Skeletal: 2.57; Whole Blood: 0.83; MNRLYLTPDGFFFRVHMLALDSSSCNKPCPEFKPGSRYIVMGHIYHKRRQLPTALLQVLRGRLRPGDGLLRSSSSYVKRFNRKREGQIQGAIHTQCI FAM104A FAM104A F104A_HUMAN (Q969W3-1) GO:0042802 (0.13) ! identical protein binding; GO:0005086 (0.13) ! ARF guanyl-nucleotide exchange factor activity; GO:0035091 (0.07) ! phosphatidylinositol binding; GO:0034987 (0.07) ! immunoglobulin receptor binding; GO:0008017 (0.07) ! microtubule binding; GO:0005524 (0.07) ! ATP binding; GO:0005096 (0.07) ! GTPase activator activity; GO:0004715 (0.07) ! non-membrane spanning protein tyrosine kinase activity GO:0044260 (0.81) ! cellular macromolecule metabolic process; GO:0044238 (0.81) ! primary metabolic process; GO:0006950 (0.81) ! response to stress; GO:0042276 (0.80) ! error-prone translesion synthesis; GO:0043547 (0.11) ! positive regulation of GTPase activity; GO:0006897 (0.11) ! endocytosis; GO:2000251 (0.06) ! positive regulation of actin cytoskeleton reorganization; GO:2000145 (0.06) ! regulation of cell motility; GO:0090339 (0.06) ! negative regulation of formin-nucleated actin cable assembly; GO:0051297 (0.06) ! centrosome organization; GO:0051056 (0.06) ! regulation of small GTPase mediated signal transduction; GO:0045639 (0.06) ! positive regulation of myeloid cell differentiation; GO:0045087 (0.06) ! innate immune response; GO:0043304 (0.06) ! regulation of mast cell degranulation; GO:0042127 (0.06) ! regulation of cell proliferation; GO:0038083 (0.06) ! peptidyl-tyrosine autophosphorylation; GO:0031116 (0.06) ! positive regulation of microtubule polymerization; GO:0030155 (0.06) ! regulation of cell adhesion; GO:0010976 (0.06) ! positive regulation of neuron projection development; GO:0008360 (0.06) ! regulation of cell shape; GO:0007173 (0.06) ! epidermal growth factor receptor signaling pathway; GO:0007067 (0.06) ! mitotic nuclear division; GO:0006935 (0.06) ! chemotaxis; GO:0001578 (0.06) ! microtubule bundle formation; GO:0000917 (0.06) ! barrier septum assembly GO:0044464 (1.00) ! cell part; GO:0043229 (0.98) ! intracellular organelle; GO:0043231 (0.96) ! intracellular membrane-bounded organelle; GO:0044446 (0.90) ! intracellular organelle part; GO:0032991 (0.86) ! macromolecular complex; GO:0043234 (0.85) ! protein complex; GO:0005634 (0.84) ! nucleus; GO:0044444 (0.82) ! cytoplasmic part; GO:0061695 (0.81) ! transferase complex, transferring phosphorus-containing groups; GO:0016035 (0.80) ! zeta DNA polymerase complex; GO:0005829 (0.68) ! cytosol; GO:0044425 (0.63) ! membrane part; GO:0016020 (0.57) ! membrane; GO:0005737 (0.57) ! cytoplasm; GO:0031982 (0.51) ! vesicle; GO:0005886 (0.51) ! plasma membrane; GO:0043232 (0.45) ! intracellular non-membrane-bounded organelle; GO:0031410 (0.45) ! cytoplasmic vesicle; GO:0030054 (0.45) ! cell junction; GO:0044459 (0.40) ! plasma membrane part; GO:0031988 (0.40) ! membrane-bounded vesicle; GO:0005773 (0.40) ! vacuole; GO:0005856 (0.34) ! cytoskeleton; GO:0098590 (0.29) ! plasma membrane region; GO:0044463 (0.29) ! cell projection part; GO:0016023 (0.29) ! cytoplasmic, membrane-bounded vesicle; GO:0005768 (0.29) ! endosome; GO:0097458 (0.24) ! neuron part; GO:0044431 (0.24) ! Golgi apparatus part; GO:0042995 (0.24) ! cell projection; GO:0030659 (0.24) ! cytoplasmic vesicle membrane; GO:0098589 (0.20) ! membrane region; GO:0048471 (0.20) ! perinuclear region of cytoplasm; GO:0044430 (0.20) ! cytoskeletal part; GO:0033267 (0.20) ! axon part; GO:0032587 (0.20) ! ruffle membrane; GO:0005925 (0.20) ! focal adhesion; GO:0005654 (0.20) ! nucleoplasm; GO:0098805 (0.15) ! whole membrane; GO:0098588 (0.15) ! bounding membrane of organelle; GO:0070062 (0.15) ! extracellular exosome; GO:0045202 (0.15) ! synapse; GO:0044456 (0.15) ! synapse part; GO:0032155 (0.15) ! cell division site part; GO:0005802 (0.15) ! trans-Golgi network; GO:0005794 (0.15) ! Golgi apparatus; GO:0071212 (0.10) ! subsynaptic reticulum; GO:0055038 (0.10) ! recycling endosome membrane; GO:0045211 (0.10) ! postsynaptic membrane; GO:0043679 (0.10) ! axon terminus; GO:0043209 (0.10) ! myelin sheath; GO:0043005 (0.10) ! neuron projection; GO:0032982 (0.10) ! myosin filament; GO:0032807 (0.10) ! DNA ligase IV complex; GO:0032154 (0.10) ! cleavage furrow; GO:0030496 (0.10) ! midbody; GO:0030137 (0.10) ! COPI-coated vesicle; GO:0030018 (0.10) ! Z disc; GO:0030017 (0.10) ! sarcomere; GO:0030016 (0.10) ! myofibril; GO:0019898 (0.10) ! extrinsic component of membrane; GO:0015630 (0.10) ! microtubule cytoskeleton; GO:0005958 (0.10) ! DNA-dependent protein kinase-DNA ligase 4 complex; GO:0005938 (0.10) ! cell cortex; GO:0005935 (0.10) ! cellular bud neck; GO:0005905 (0.10) ! clathrin-coated pit; GO:0005901 (0.10) ! caveola; GO:0005859 (0.10) ! muscle myosin complex; GO:0005813 (0.10) ! centrosome; GO:0005769 (0.10) ! early endosome; GO:0005764 (0.10) ! lysosome; GO:0001725 (0.10) ! stress fiber; GO:0000793 (0.10) ! condensed chromosome; GO:0072562 (0.05) ! blood microparticle; GO:0044697 (0.05) ! HICS complex; GO:0042627 (0.05) ! chylomicron; GO:0034366 (0.05) ! spherical high-density lipoprotein particle; GO:0034365 (0.05) ! discoidal high-density lipoprotein particle; GO:0034361 (0.05) ! very-low-density lipoprotein particle; GO:0031234 (0.05) ! extrinsic component of cytoplasmic side of plasma membrane; GO:0030672 (0.05) ! synaptic vesicle membrane; GO:0030139 (0.05) ! endocytic vesicle; GO:0030133 (0.05) ! transport vesicle; GO:0016021 (0.05) ! integral component of membrane; GO:0012505 (0.05) ! endomembrane system; GO:0009986 (0.05) ! cell surface; GO:0005942 (0.05) ! phosphatidylinositol 3-kinase complex; GO:0005934 (0.05) ! cellular bud tip; GO:0005913 (0.05) ! cell-cell adherens junction; GO:0005903 (0.05) ! brush border; GO:0005874 (0.05) ! microtubule; GO:0005777 (0.05) ! peroxisome; GO:0005741 (0.05) ! mitochondrial outer membrane; GO:0005739 (0.05) ! mitochondrion; GO:0005615 (0.05) ! extracellular space; GO:0005576 (0.05) ! extracellular region; GO:0001891 (0.05) ! phagocytic cup; GO:0000144 (0.05) ! cellular bud neck septin ring; GO:0000142 (0.05) ! cellular bud neck contractile ring GO:0005515 ! protein binding 2 GO:0005515 ! protein binding 73207353-73236753 (17q25.1) Testis: 140.40; Cells - EBV-transformed lymphocytes: 49.85; Cells - Transformed fibroblasts: 34.17; Skin - Sun Exposed (Lower leg): 23.85; Skin - Not Sun Exposed (Suprapubic): 23.27; Cervix - Endocervix: 22.90; Cervix - Ectocervix: 22.40; Adipose - Subcutaneous: 21.89; Bladder: 21.26; Artery - Tibial: 21.19; Artery - Aorta: 20.76; Vagina: 20.54; Breast - Mammary Tissue: 20.18; Pituitary: 19.60; Fallopian Tube: 19.44; Artery - Coronary: 19.41; Esophagus - Mucosa: 18.98; Lung: 18.66; Thyroid: 18.64; Uterus: 18.59; Prostate: 18.59; Nerve - Tibial: 18.56; Brain - Cerebellar Hemisphere: 18.30; Spleen: 18.00; Adipose - Visceral (Omentum): 17.68; Ovary: 17.42; Brain - Cerebellum: 16.99; Whole Blood: 16.94; Esophagus - Muscularis: 15.19; Esophagus - Gastroesophageal Junction: 14.83; Minor Salivary Gland: 14.52; Colon - Sigmoid: 14.18; Small Intestine - Terminal Ileum: 14.09; Stomach: 13.49; Colon - Transverse: 13.07; Adrenal Gland: 12.63; Brain - Spinal cord (cervical c-1): 11.38; Brain - Frontal Cortex (BA9): 11.16; Brain - Cortex: 10.62; Brain - Nucleus accumbens (basal ganglia): 10.42; Muscle - Skeletal: 10.10; Brain - Anterior cingulate cortex (BA24): 8.77; Brain - Hypothalamus: 8.58; Brain - Caudate (basal ganglia): 8.54; Pancreas: 7.97; Brain - Amygdala: 7.91; Kidney - Cortex: 7.78; Heart - Atrial Appendage: 7.66; Brain - Substantia nigra: 7.56; Brain - Hippocampus: 7.38; Brain - Putamen (basal ganglia): 6.85; Liver: 6.04; Heart - Left Ventricle: 5.60; MGGRGADAGSSGGTGPTEGYSPPAASTRAAARAKARGGGRGGRRNTTPSVPSLRGAAPRSFHPPAAMSERLRPRKRRRNGNEEDNHLPPQTKRSSRNPVFQDSWDTESSGSDSGGSSSSSSSSINSPDRASGPEGSLSQTMAGSSPNTPQPVPEQSALCQGLYFHINQTLREAHFHSLQHRGRPLT C17orf80 Uncharacterized protein C17orf80 CQ080_HUMAN (Q9BSJ5-1) GO:1901363 (0.43) ! heterocyclic compound binding; GO:0097159 (0.43) ! organic cyclic compound binding; GO:0097367 (0.40) ! carbohydrate derivative binding; GO:0035639 (0.39) ! purine ribonucleoside triphosphate binding; GO:0032559 (0.39) ! adenyl ribonucleotide binding; GO:0032550 (0.39) ! purine ribonucleoside binding; GO:0008092 (0.35) ! cytoskeletal protein binding; GO:0003676 (0.35) ! nucleic acid binding; GO:0003824 (0.34) ! catalytic activity; GO:0043169 (0.30) ! cation binding; GO:0005198 (0.20) ! structural molecule activity; GO:0005201 (0.16) ! extracellular matrix structural constituent; GO:0030674 (0.14) ! protein binding, bridging; GO:0030507 (0.12) ! spectrin binding; GO:0008093 (0.12) ! cytoskeletal adaptor activity; GO:0098772 (0.10) ! molecular function regulator; GO:0005096 (0.09) ! GTPase activator activity; GO:0016787 (0.07) ! hydrolase activity; GO:0019899 (0.06) ! enzyme binding; GO:0003677 (0.05) ! DNA binding; GO:0044822 (0.04) ! poly(A) RNA binding; GO:0017016 (0.04) ! Ras GTPase binding; GO:0016887 (0.04) ! ATPase activity; GO:0042623 (0.03) ! ATPase activity, coupled; GO:0032403 (0.03) ! protein complex binding; GO:0017137 (0.03) ! Rab GTPase binding; GO:0003779 (0.03) ! actin binding; GO:0003714 (0.03) ! transcription corepressor activity; GO:0051015 (0.02) ! actin filament binding; GO:0046983 (0.02) ! protein dimerization activity; GO:0044212 (0.02) ! transcription regulatory region DNA binding; GO:0022892 (0.02) ! substrate-specific transporter activity; GO:0019904 (0.02) ! protein domain specific binding; GO:0019901 (0.02) ! protein kinase binding; GO:0016811 (0.02) ! hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; GO:0008307 (0.02) ! structural constituent of muscle; GO:0008134 (0.02) ! transcription factor binding; GO:0008017 (0.02) ! microtubule binding; GO:0005200 (0.02) ! structural constituent of cytoskeleton; GO:0004672 (0.02) ! protein kinase activity; GO:0003700 (0.02) ! transcription factor activity, sequence-specific DNA binding; GO:0001191 (0.02) ! transcriptional repressor activity, RNA polymerase II transcription factor binding; GO:0097493 (0.01) ! structural molecule activity conferring elasticity; GO:0070087 (0.01) ! chromo shadow domain binding; GO:0051371 (0.01) ! muscle alpha-actinin binding; GO:0051117 (0.01) ! ATPase binding; GO:0047485 (0.01) ! protein N-terminus binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0045502 (0.01) ! dynein binding; GO:0045295 (0.01) ! gamma-catenin binding; GO:0044325 (0.01) ! ion channel binding; GO:0043565 (0.01) ! sequence-specific DNA binding; GO:0043531 (0.01) ! ADP binding; GO:0043495 (0.01) ! protein anchor; GO:0042826 (0.01) ! histone deacetylase binding; GO:0042803 (0.01) ! protein homodimerization activity; GO:0036033 (0.01) ! mediator complex binding; GO:0033040 (0.01) ! sour taste receptor activity; GO:0032027 (0.01) ! myosin light chain binding; GO:0030983 (0.01) ! mismatched DNA binding; GO:0030898 (0.01) ! actin-dependent ATPase activity; GO:0019902 (0.01) ! phosphatase binding; GO:0019894 (0.01) ! kinesin binding; GO:0017048 (0.01) ! Rho GTPase binding; GO:0015643 (0.01) ! toxic substance binding; GO:0008565 (0.01) ! protein transporter activity; GO:0008270 (0.01) ! zinc ion binding; GO:0008022 (0.01) ! protein C-terminus binding; GO:0008013 (0.01) ! beta-catenin binding; GO:0005524 (0.01) ! ATP binding; GO:0005262 (0.01) ! calcium channel activity; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0004843 (0.01) ! thiol-dependent ubiquitin-specific protease activity; GO:0004407 (0.01) ! histone deacetylase activity; GO:0004004 (0.01) ! ATP-dependent RNA helicase activity; GO:0003918 (0.01) ! DNA topoisomerase type II (ATP-hydrolyzing) activity; GO:0003697 (0.01) ! single-stranded DNA binding; GO:0003684 (0.01) ! damaged DNA binding; GO:0003682 (0.01) ! chromatin binding; GO:0001106 (0.01) ! RNA polymerase II transcription corepressor activity; GO:0001085 (0.01) ! RNA polymerase II transcription factor binding; GO:0001047 (0.01) ! core promoter binding; GO:0000146 (0.01) ! microfilament motor activity GO:0009987 (0.71) ! cellular process; GO:0044699 (0.64) ! single-organism process; GO:0065007 (0.63) ! biological regulation; GO:0044763 (0.62) ! single-organism cellular process; GO:0032501 (0.47) ! multicellular organismal process; GO:0044767 (0.46) ! single-organism developmental process; GO:0016043 (0.46) ! cellular component organization; GO:0065008 (0.44) ! regulation of biological quality; GO:0050794 (0.42) ! regulation of cellular process; GO:0044707 (0.37) ! single-multicellular organism process; GO:0006996 (0.33) ! organelle organization; GO:0051239 (0.30) ! regulation of multicellular organismal process; GO:0023051 (0.29) ! regulation of signaling; GO:0010646 (0.29) ! regulation of cell communication; GO:0003008 (0.29) ! system process; GO:1902589 (0.27) ! single-organism organelle organization; GO:0050877 (0.27) ! neurological system process; GO:0007600 (0.26) ! sensory perception; GO:0007010 (0.26) ! cytoskeleton organization; GO:0051128 (0.24) ! regulation of cellular component organization; GO:0048856 (0.24) ! anatomical structure development; GO:0019233 (0.24) ! sensory perception of pain; GO:0048523 (0.23) ! negative regulation of cellular process; GO:0048518 (0.23) ! positive regulation of biological process; GO:0048522 (0.22) ! positive regulation of cellular process; GO:0050793 (0.20) ! regulation of developmental process; GO:0048589 (0.20) ! developmental growth; GO:0009653 (0.20) ! anatomical structure morphogenesis; GO:2000026 (0.19) ! regulation of multicellular organismal development; GO:0060560 (0.19) ! developmental growth involved in morphogenesis; GO:0051179 (0.19) ! localization; GO:0050890 (0.19) ! cognition; GO:0048588 (0.19) ! developmental cell growth; GO:0007154 (0.19) ! cell communication; GO:0000226 (0.19) ! microtubule cytoskeleton organization; GO:0051962 (0.18) ! positive regulation of nervous system development; GO:0051641 (0.18) ! cellular localization; GO:0050807 (0.18) ! regulation of synapse organization; GO:0044087 (0.18) ! regulation of cellular component biogenesis; GO:0023057 (0.18) ! negative regulation of signaling; GO:0010648 (0.18) ! negative regulation of cell communication; GO:0007613 (0.18) ! memory; GO:0006810 (0.18) ! transport; GO:1900074 (0.17) ! negative regulation of neuromuscular synaptic transmission; GO:0070050 (0.17) ! neuron cellular homeostasis; GO:0051649 (0.17) ! establishment of localization in cell; GO:0048675 (0.17) ! axon extension; GO:0045887 (0.17) ! positive regulation of synaptic growth at neuromuscular junction; GO:0008104 (0.17) ! protein localization; GO:0007614 (0.17) ! short-term memory; GO:0007605 (0.17) ! sensory perception of sound; GO:0007528 (0.17) ! neuromuscular junction development; GO:0090066 (0.16) ! regulation of anatomical structure size; GO:0046907 (0.16) ! intracellular transport; GO:0015031 (0.16) ! protein transport; GO:0044700 (0.15) ! single organism signaling; GO:0032879 (0.15) ! regulation of localization; GO:0009886 (0.15) ! post-embryonic morphogenesis; GO:0008152 (0.15) ! metabolic process; GO:0006886 (0.15) ! intracellular protein transport; GO:1902578 (0.14) ! single-organism localization; GO:0046331 (0.14) ! lateral inhibition; GO:0044719 (0.14) ! regulation of imaginal disc-derived wing size; GO:0044238 (0.14) ! primary metabolic process; GO:0044237 (0.14) ! cellular metabolic process; GO:0043170 (0.14) ! macromolecule metabolic process; GO:0040005 (0.14) ! chitin-based cuticle attachment to epithelium; GO:0008362 (0.14) ! chitin-based embryonic cuticle biosynthetic process; GO:0007475 (0.14) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.14) ! open tracheal system development; GO:1902580 (0.13) ! single-organism cellular localization; GO:0061024 (0.13) ! membrane organization; GO:0044765 (0.13) ! single-organism transport; GO:0044260 (0.13) ! cellular macromolecule metabolic process; GO:0022607 (0.13) ! cellular component assembly; GO:0051270 (0.12) ! regulation of cellular component movement; GO:0034613 (0.12) ! cellular protein localization; GO:0032970 (0.12) ! regulation of actin filament-based process; GO:0098910 (0.11) ! regulation of atrial cardiac muscle cell action potential; GO:0072661 (0.11) ! protein targeting to plasma membrane; GO:0065009 (0.10) ! regulation of molecular function; GO:0051716 (0.10) ! cellular response to stimulus; GO:0043933 (0.10) ! macromolecular complex subunit organization; GO:0006139 (0.10) ! nucleobase-containing compound metabolic process; GO:0090304 (0.09) ! nucleic acid metabolic process; GO:0048869 (0.09) ! cellular developmental process; GO:0043087 (0.09) ! regulation of GTPase activity; GO:0034622 (0.09) ! cellular macromolecular complex assembly; GO:0033554 (0.09) ! cellular response to stress; GO:0060255 (0.08) ! regulation of macromolecule metabolic process; GO:0016070 (0.08) ! RNA metabolic process; GO:0080090 (0.07) ! regulation of primary metabolic process; GO:0030036 (0.07) ! actin cytoskeleton organization; GO:0022414 (0.07) ! reproductive process; GO:0010468 (0.07) ! regulation of gene expression; GO:0006974 (0.07) ! cellular response to DNA damage stimulus; GO:0006396 (0.07) ! RNA processing; GO:0034645 (0.06) ! cellular macromolecule biosynthetic process; GO:0032508 (0.06) ! DNA duplex unwinding; GO:0031668 (0.06) ! cellular response to extracellular stimulus; GO:0031323 (0.06) ! regulation of cellular metabolic process; GO:0006310 (0.06) ! DNA recombination; GO:0006281 (0.06) ! DNA repair; GO:0090502 (0.05) ! RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0048646 (0.05) ! anatomical structure formation involved in morphogenesis; GO:0044702 (0.05) ! single organism reproductive process; GO:0033043 (0.05) ! regulation of organelle organization; GO:0031054 (0.05) ! pre-miRNA processing; GO:0031053 (0.05) ! primary miRNA processing; GO:0031032 (0.05) ! actomyosin structure organization; GO:0030422 (0.05) ! production of siRNA involved in RNA interference; GO:0022402 (0.05) ! cell cycle process; GO:0019538 (0.05) ! protein metabolic process; GO:0010604 (0.05) ! positive regulation of macromolecule metabolic process; GO:0010501 (0.05) ! RNA secondary structure unwinding; GO:0009432 (0.05) ! SOS response; GO:0006355 (0.05) ! regulation of transcription, DNA-templated; GO:0006260 (0.05) ! DNA replication; GO:0000348 (0.05) ! mRNA branch site recognition; GO:0051049 (0.04) ! regulation of transport; GO:0048468 (0.04) ! cell development; GO:0045892 (0.04) ! negative regulation of transcription, DNA-templated; GO:0043623 (0.04) ! cellular protein complex assembly; GO:0031325 (0.04) ! positive regulation of cellular metabolic process; GO:0030154 (0.04) ! cell differentiation; GO:0030030 (0.04) ! cell projection organization; GO:0010927 (0.04) ! cellular component assembly involved in morphogenesis; GO:0010628 (0.04) ! positive regulation of gene expression; GO:0007519 (0.04) ! skeletal muscle tissue development; GO:0006464 (0.04) ! cellular protein modification process; GO:0006357 (0.04) ! regulation of transcription from RNA polymerase II promoter; GO:1903046 (0.03) ! meiotic cell cycle process; GO:0051247 (0.03) ! positive regulation of protein metabolic process; GO:0044093 (0.03) ! positive regulation of molecular function; GO:0034088 (0.03) ! maintenance of mitotic sister chromatid cohesion; GO:0032989 (0.03) ! cellular component morphogenesis; GO:0030239 (0.03) ! myofibril assembly; GO:0006796 (0.03) ! phosphate-containing compound metabolic process; GO:0000122 (0.03) ! negative regulation of transcription from RNA polymerase II promoter; GO:2000331 (0.02) ! regulation of terminal button organization; GO:1901880 (0.02) ! negative regulation of protein depolymerization; GO:0090630 (0.02) ! activation of GTPase activity; GO:0061564 (0.02) ! axon development; GO:0060341 (0.02) ! regulation of cellular localization; GO:0051726 (0.02) ! regulation of cell cycle; GO:0051494 (0.02) ! negative regulation of cytoskeleton organization; GO:0048729 (0.02) ! tissue morphogenesis; GO:0048699 (0.02) ! generation of neurons; GO:0048674 (0.02) ! collateral sprouting of injured axon; GO:0048666 (0.02) ! neuron development; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0045893 (0.02) ! positive regulation of transcription, DNA-templated; GO:0045595 (0.02) ! regulation of cell differentiation; GO:0045214 (0.02) ! sarcomere organization; GO:0045110 (0.02) ! intermediate filament bundle assembly; GO:0044710 (0.02) ! single-organism metabolic process; GO:0035112 (0.02) ! genitalia morphogenesis; GO:0035107 (0.02) ! appendage morphogenesis; GO:0032886 (0.02) ! regulation of microtubule-based process; GO:0032270 (0.02) ! positive regulation of cellular protein metabolic process; GO:0031338 (0.02) ! regulation of vesicle fusion; GO:0030241 (0.02) ! skeletal muscle myosin thick filament assembly; GO:0022604 (0.02) ! regulation of cell morphogenesis; GO:0016477 (0.02) ! cell migration; GO:0014866 (0.02) ! skeletal myofibril assembly; GO:0007616 (0.02) ! long-term memory; GO:0007283 (0.02) ! spermatogenesis; GO:0007165 (0.02) ! signal transduction; GO:0007030 (0.02) ! Golgi organization; GO:0007015 (0.02) ! actin filament organization; GO:0006888 (0.02) ! ER to Golgi vesicle-mediated transport; GO:0006812 (0.02) ! cation transport; GO:0006508 (0.02) ! proteolysis; GO:0006468 (0.02) ! protein phosphorylation; GO:0000902 (0.02) ! cell morphogenesis; GO:2001259 (0.01) ! positive regulation of cation channel activity; GO:2000210 (0.01) ! positive regulation of anoikis; GO:1903937 (0.01) ! response to acrylamide; GO:1903935 (0.01) ! response to sodium arsenite; GO:1903923 (0.01) ! positive regulation of protein processing in phagocytic vesicle; GO:1903919 (0.01) ! negative regulation of actin filament severing; GO:1902513 (0.01) ! regulation of organelle transport along microtubule; GO:1901021 (0.01) ! positive regulation of calcium ion transmembrane transporter activity; GO:1901018 (0.01) ! positive regulation of potassium ion transmembrane transporter activity; GO:0098907 (0.01) ! regulation of SA node cell action potential; GO:0090090 (0.01) ! negative regulation of canonical Wnt signaling pathway; GO:0086091 (0.01) ! regulation of heart rate by cardiac conduction; GO:0086070 (0.01) ! SA node cell to atrial cardiac muscle cell communication; GO:0086066 (0.01) ! atrial cardiac muscle cell to AV node cell communication; GO:0086046 (0.01) ! membrane depolarization during SA node cell action potential; GO:0086015 (0.01) ! SA node cell action potential; GO:0086014 (0.01) ! atrial cardiac muscle cell action potential; GO:0086005 (0.01) ! ventricular cardiac muscle cell action potential; GO:0072332 (0.01) ! intrinsic apoptotic signaling pathway by p53 class mediator; GO:0071481 (0.01) ! cellular response to X-ray; GO:0071468 (0.01) ! cellular response to acidic pH; GO:0071392 (0.01) ! cellular response to estradiol stimulus; GO:0071277 (0.01) ! cellular response to calcium ion; GO:0071158 (0.01) ! positive regulation of cell cycle arrest; GO:0070972 (0.01) ! protein localization to endoplasmic reticulum; GO:0070527 (0.01) ! platelet aggregation; GO:0070296 (0.01) ! sarcoplasmic reticulum calcium ion transport; GO:0061038 (0.01) ! uterus morphogenesis; GO:0061025 (0.01) ! membrane fusion; GO:0061010 (0.01) ! gall bladder development; GO:0060562 (0.01) ! epithelial tube morphogenesis; GO:0060325 (0.01) ! face morphogenesis; GO:0060307 (0.01) ! regulation of ventricular cardiac muscle cell membrane repolarization; GO:0060047 (0.01) ! heart contraction; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051693 (0.01) ! actin filament capping; GO:0051295 (0.01) ! establishment of meiotic spindle localization; GO:0051292 (0.01) ! nuclear pore complex assembly; GO:0050982 (0.01) ! detection of mechanical stimulus; GO:0050915 (0.01) ! sensory perception of sour taste; GO:0050821 (0.01) ! protein stabilization; GO:0050769 (0.01) ! positive regulation of neurogenesis; GO:0048803 (0.01) ! imaginal disc-derived male genitalia morphogenesis; GO:0048739 (0.01) ! cardiac muscle fiber development; GO:0048738 (0.01) ! cardiac muscle tissue development; GO:0048703 (0.01) ! embryonic viscerocranium morphogenesis; GO:0048701 (0.01) ! embryonic cranial skeleton morphogenesis; GO:0048619 (0.01) ! embryonic hindgut morphogenesis; GO:0048592 (0.01) ! eye morphogenesis; GO:0048570 (0.01) ! notochord morphogenesis; GO:0048557 (0.01) ! embryonic digestive tract morphogenesis; GO:0048211 (0.01) ! Golgi vesicle docking; GO:0046034 (0.01) ! ATP metabolic process; GO:0045995 (0.01) ! regulation of embryonic development; GO:0045778 (0.01) ! positive regulation of ossification; GO:0045732 (0.01) ! positive regulation of protein catabolic process; GO:0045444 (0.01) ! fat cell differentiation; GO:0045056 (0.01) ! transcytosis; GO:0044774 (0.01) ! mitotic DNA integrity checkpoint; GO:0043534 (0.01) ! blood vessel endothelial cell migration; GO:0042634 (0.01) ! regulation of hair cycle; GO:0042471 (0.01) ! ear morphogenesis; GO:0042220 (0.01) ! response to cocaine; GO:0042149 (0.01) ! cellular response to glucose starvation; GO:0040018 (0.01) ! positive regulation of multicellular organism growth; GO:0036371 (0.01) ! protein localization to T-tubule; GO:0036309 (0.01) ! protein localization to M-band; GO:0036091 (0.01) ! positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress; GO:0035296 (0.01) ! regulation of tube diameter; GO:0035261 (0.01) ! external genitalia morphogenesis; GO:0035115 (0.01) ! embryonic forelimb morphogenesis; GO:0034599 (0.01) ! cellular response to oxidative stress; GO:0034394 (0.01) ! protein localization to cell surface; GO:0033693 (0.01) ! neurofilament bundle assembly; GO:0033292 (0.01) ! T-tubule organization; GO:0032922 (0.01) ! circadian regulation of gene expression; GO:0032796 (0.01) ! uropod organization; GO:0031532 (0.01) ! actin cytoskeleton reorganization; GO:0031103 (0.01) ! axon regeneration; GO:0031065 (0.01) ! positive regulation of histone deacetylation; GO:0030282 (0.01) ! bone mineralization; GO:0030240 (0.01) ! skeletal muscle thin filament assembly; GO:0030224 (0.01) ! monocyte differentiation; GO:0030220 (0.01) ! platelet formation; GO:0030048 (0.01) ! actin filament-based movement; GO:0030041 (0.01) ! actin filament polymerization; GO:0030031 (0.01) ! cell projection assembly; GO:0022904 (0.01) ! respiratory electron transport chain; GO:0021987 (0.01) ! cerebral cortex development; GO:0021766 (0.01) ! hippocampus development; GO:0021510 (0.01) ! spinal cord development; GO:0019827 (0.01) ! stem cell population maintenance; GO:0016579 (0.01) ! protein deubiquitination; GO:0016575 (0.01) ! histone deacetylation; GO:0010881 (0.01) ! regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; GO:0008360 (0.01) ! regulation of cell shape; GO:0008283 (0.01) ! cell proliferation; GO:0007520 (0.01) ! myoblast fusion; GO:0007507 (0.01) ! heart development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007420 (0.01) ! brain development; GO:0007409 (0.01) ! axonogenesis; GO:0007389 (0.01) ! pattern specification process; GO:0007131 (0.01) ! reciprocal meiotic recombination; GO:0007064 (0.01) ! mitotic sister chromatid cohesion; GO:0007026 (0.01) ! negative regulation of microtubule depolymerization; GO:0006941 (0.01) ! striated muscle contraction; GO:0006913 (0.01) ! nucleocytoplasmic transport; GO:0006911 (0.01) ! phagocytosis, engulfment; GO:0006874 (0.01) ! cellular calcium ion homeostasis; GO:0006509 (0.01) ! membrane protein ectodomain proteolysis; GO:0006366 (0.01) ! transcription from RNA polymerase II promoter; GO:0006312 (0.01) ! mitotic recombination; GO:0006268 (0.01) ! DNA unwinding involved in DNA replication; GO:0006265 (0.01) ! DNA topological change; GO:0003283 (0.01) ! atrial septum development; GO:0003151 (0.01) ! outflow tract morphogenesis; GO:0003007 (0.01) ! heart morphogenesis; GO:0002064 (0.01) ! epithelial cell development; GO:0001768 (0.01) ! establishment of T cell polarity; GO:0001708 (0.01) ! cell fate specification; GO:0001701 (0.01) ! in utero embryonic development; GO:0001649 (0.01) ! osteoblast differentiation; GO:0001581 (0.01) ! detection of chemical stimulus involved in sensory perception of sour taste; GO:0001552 (0.01) ! ovarian follicle atresia; GO:0001525 (0.01) ! angiogenesis; GO:0001501 (0.01) ! skeletal system development; GO:0000910 (0.01) ! cytokinesis; GO:0000904 (0.01) ! cell morphogenesis involved in differentiation; GO:0000819 (0.01) ! sister chromatid segregation; GO:0000712 (0.01) ! resolution of meiotic recombination intermediates; GO:0000710 (0.01) ! meiotic mismatch repair; GO:0000398 (0.01) ! mRNA splicing, via spliceosome; GO:0000212 (0.01) ! meiotic spindle organization GO:0070062 (0.97) ! extracellular exosome; GO:0005753 (0.03) ! mitochondrial proton-transporting ATP synthase complex GO:0070062 ! extracellular exosome GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 73232233-73248947 (17q25.1) Testis: 36.04; Brain - Cerebellar Hemisphere: 19.23; Cervix - Endocervix: 18.88; Uterus: 18.29; Brain - Cerebellum: 17.64; Ovary: 17.46; Thyroid: 16.31; Fallopian Tube: 15.56; Colon - Sigmoid: 15.52; Cells - Transformed fibroblasts: 15.40; Pituitary: 15.35; Cells - EBV-transformed lymphocytes: 14.82; Bladder: 13.84; Esophagus - Gastroesophageal Junction: 13.82; Nerve - Tibial: 13.68; Esophagus - Muscularis: 13.63; Artery - Tibial: 13.11; Prostate: 13.10; Cervix - Ectocervix: 12.82; Artery - Coronary: 12.64; Artery - Aorta: 12.20; Muscle - Skeletal: 12.04; Spleen: 11.78; Vagina: 10.04; Adrenal Gland: 9.94; Adipose - Subcutaneous: 9.80; Lung: 9.57; Breast - Mammary Tissue: 9.51; Small Intestine - Terminal Ileum: 9.01; Minor Salivary Gland: 8.99; Colon - Transverse: 8.73; Adipose - Visceral (Omentum): 8.54; Brain - Spinal cord (cervical c-1): 8.36; Stomach: 8.18; Brain - Frontal Cortex (BA9): 8.13; Brain - Cortex: 7.97; Brain - Hypothalamus: 7.47; Skin - Sun Exposed (Lower leg): 7.12; Brain - Nucleus accumbens (basal ganglia): 7.05; Skin - Not Sun Exposed (Suprapubic): 7.03; Brain - Anterior cingulate cortex (BA24): 6.73; Brain - Caudate (basal ganglia): 6.69; Esophagus - Mucosa: 6.63; Brain - Substantia nigra: 6.52; Kidney - Cortex: 6.47; Heart - Atrial Appendage: 6.21; Heart - Left Ventricle: 5.86; Brain - Hippocampus: 5.61; Brain - Amygdala: 5.53; Brain - Putamen (basal ganglia): 5.35; Pancreas: 4.79; Liver: 3.98; Whole Blood: 2.07; MSDNPPRMEVCPYCKKPFKRLKSHLPYCKMIGPTIPTDQKVYQSKPATLPRAKKMKGPIKDLIKAKGKELETENEERNSKLVVDKPEQTVKTFPLPAVGLERAATTKADKDIKNPIQPSFKMLKNTKPMTTFQEETKAQFYASEKTSPKRELAKDLPKSGESRCNPSEAGASLLVGSIEPSLSNQDRKYSSTLPNDVQTTSGDLKLDKIDPQRQELLVKLLDVPTGDCHISPKNVSDGVKRVRTLLSNERDSKGRDHLSGVPTDVTVTETPEKNTESLILSLKMSSLGKIQVMEKQEKGLTLGVETCGSKGNAEKSMSATEKQERTVMSHGCENFNTRDSVTGKESQGERPHLSLFIPRETTYQFHSVSQSSSQSLASLATTFLQEKKAEAQNHHCVPDVKALMESPEGQLSLEPKSDSQFQASHTGCQSPLCSAQRHTPQSPFTNHAAAAGRKTLRSCMGLEWFPELYPGYLGLGVLPGKPQCWNAMTQKPQLISPQGERLSQVSLLERSSTHIRSLEPPAGLTTSNFSLMRLLGAVQKGWIRCNTTIRKSGFGGITMLFTGYFVLCCSWSFRRLKKLCRPLPWKSTVPPCIGVAKTTGDCRSKTCLD OTOP2 Otopetrin-2 OTOP2_HUMAN (Q7RTS6-1) GO:0046983 (0.55) ! protein dimerization activity; GO:0046873 (0.55) ! metal ion transmembrane transporter activity; GO:0042802 (0.55) ! identical protein binding; GO:0031420 (0.55) ! alkali metal ion binding; GO:0015077 (0.55) ! monovalent inorganic cation transmembrane transporter activity; GO:0009678 (0.39) ! hydrogen-translocating pyrophosphatase activity; GO:0004427 (0.39) ! inorganic diphosphatase activity GO:0042472 (1.00) ! inner ear morphogenesis; GO:0009590 (0.51) ! detection of gravity; GO:0045299 (0.49) ! otolith mineralization; GO:0032475 (0.49) ! otolith formation; GO:0098662 (0.41) ! inorganic cation transmembrane transport; GO:0030001 (0.41) ! metal ion transport; GO:0015992 (0.28) ! proton transport GO:0016020 (0.86) ! membrane; GO:0044464 (0.72) ! cell part; GO:0016021 (0.61) ! integral component of membrane; GO:0032991 (0.35) ! macromolecular complex; GO:0005886 (0.35) ! plasma membrane; GO:0044424 (0.31) ! intracellular part; GO:0043234 (0.31) ! protein complex; GO:1902494 (0.27) ! catalytic complex; GO:0005737 (0.24) ! cytoplasm; GO:0044459 (0.20) ! plasma membrane part; GO:0009380 (0.20) ! excinuclease repair complex; GO:0044444 (0.13) ! cytoplasmic part; GO:0098797 (0.10) ! plasma membrane protein complex; GO:0070469 (0.10) ! respiratory chain; GO:0043226 (0.10) ! organelle; GO:0005887 (0.10) ! integral component of plasma membrane; GO:0043229 (0.07) ! intracellular organelle; GO:0043227 (0.07) ! membrane-bounded organelle; GO:0043190 (0.07) ! ATP-binding cassette (ABC) transporter complex; GO:0016324 (0.07) ! apical plasma membrane; GO:0005829 (0.07) ! cytosol; GO:0005618 (0.07) ! cell wall; GO:0070470 (0.03) ! plasma membrane respiratory chain; GO:0070062 (0.03) ! extracellular exosome; GO:0046581 (0.03) ! intercellular canaliculus; GO:0045278 (0.03) ! plasma membrane respiratory chain complex IV; GO:0045177 (0.03) ! apical part of cell; GO:0043235 (0.03) ! receptor complex; GO:0042788 (0.03) ! polysomal ribosome; GO:0022626 (0.03) ! cytosolic ribosome; GO:0010494 (0.03) ! cytoplasmic stress granule; GO:0009986 (0.03) ! cell surface; GO:0005774 (0.03) ! vacuolar membrane; GO:0005773 (0.03) ! vacuole Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. {ECO:0000250|UniProtKB:Q80SX5}. GO:1902600 ! proton transmembrane transport; GO:0015252 ! proton channel activity GO:0005886 ! plasma membrane; GO:0016020 ! membrane; GO:0006811 ! ion transport; GO:0016021 ! integral component of membrane 2 74924275-74933912 (17q25.1) Colon - Transverse: 12.45; Testis: 10.48; Esophagus - Mucosa: 1.68; Small Intestine - Terminal Ileum: 1.53; Skin - Sun Exposed (Lower leg): 0.39; Uterus: 0.30; Skin - Not Sun Exposed (Suprapubic): 0.13; Vagina: 0.11; Brain - Cerebellum: 0.07; Cervix - Ectocervix: 0.06; Brain - Cerebellar Hemisphere: 0.06; Bladder: 0.05; Colon - Sigmoid: 0.05; Brain - Nucleus accumbens (basal ganglia): 0.03; Fallopian Tube: 0.02; Nerve - Tibial: 0.02; Spleen: 0.02; Minor Salivary Gland: 0.02; Adipose - Subcutaneous: 0.02; Adrenal Gland: 0.02; Brain - Caudate (basal ganglia): 0.01; Whole Blood: 0.01; MSEELAQGPKESPPAPRAGPREVWKKGGRLLSVLLAVNVLLLACTLISGGAFNKVAVYDTDVFALLTAMMLLATLWILFYLLRTVRCPCAVPYRDAHAGPIWLRGGLVLFGICTLIMDVFKTGYYSSFFECQSAIKILHPLIQAVFVIIQTYFLWVSAKDCVHVHLDLTWCGLMFTLTTNLAIWMAAVVDESVHQSHSYSSSHSNASHARLISDQHADNPVGGDSCLCSTAVCQIFQQGYFYLYPFNIEYSLFASTMLYVMWKNVGRFLASTPGHSHTPTPVSLFRETFFAGPVLGLLLFVVGLAVFIIYEVQVSGDGSRTRQALVIYYSFNIVCLGLTTLVSLSGSIIYRFDRRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVAGTPQDLLAGLNLTHALLMIAQHTFQNMFIIESLHRGPPGAEPHSTHPKEPCQDLTFTNLDALHTLSACPPNPGLVSPSPSDQREAVAIVSTPRSQWRRQCLKDISLFLLLCNVILWIMPAFGARPHFSNTVEVDFYGYSLWAVIVNICLPFGIFYRMHAVSSLLEVYVLS CDR2L Cerebellar degeneration-related protein 2-like CDR2L_HUMAN (Q86X02-1) GO:0003824 (0.49) ! catalytic activity; GO:0016787 (0.46) ! hydrolase activity; GO:0017111 (0.45) ! nucleoside-triphosphatase activity; GO:0008092 (0.37) ! cytoskeletal protein binding; GO:1901363 (0.35) ! heterocyclic compound binding; GO:0097159 (0.35) ! organic cyclic compound binding; GO:0035639 (0.33) ! purine ribonucleoside triphosphate binding; GO:0032559 (0.33) ! adenyl ribonucleotide binding; GO:0032550 (0.33) ! purine ribonucleoside binding; GO:0016887 (0.19) ! ATPase activity; GO:0003774 (0.19) ! motor activity; GO:0003777 (0.16) ! microtubule motor activity; GO:0019899 (0.07) ! enzyme binding; GO:0016740 (0.05) ! transferase activity; GO:0008574 (0.05) ! ATP-dependent microtubule motor activity, plus-end-directed; GO:0042802 (0.04) ! identical protein binding; GO:0005215 (0.04) ! transporter activity; GO:0005198 (0.04) ! structural molecule activity; GO:0046983 (0.03) ! protein dimerization activity; GO:0044877 (0.03) ! macromolecular complex binding; GO:0019901 (0.03) ! protein kinase binding; GO:0017016 (0.03) ! Ras GTPase binding; GO:0008017 (0.03) ! microtubule binding; GO:0004674 (0.03) ! protein serine/threonine kinase activity; GO:0003779 (0.03) ! actin binding; GO:0003676 (0.03) ! nucleic acid binding; GO:0060090 (0.02) ! binding, bridging; GO:0051015 (0.02) ! actin filament binding; GO:0042803 (0.02) ! protein homodimerization activity; GO:0042623 (0.02) ! ATPase activity, coupled; GO:0030695 (0.02) ! GTPase regulator activity; GO:0019904 (0.02) ! protein domain specific binding; GO:0017137 (0.02) ! Rab GTPase binding; GO:0005524 (0.02) ! ATP binding; GO:0005487 (0.02) ! nucleocytoplasmic transporter activity; GO:0004842 (0.02) ! ubiquitin-protein transferase activity; GO:0003723 (0.02) ! RNA binding; GO:0000146 (0.02) ! microfilament motor activity; GO:0098641 (0.01) ! cadherin binding involved in cell-cell adhesion; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0046872 (0.01) ! metal ion binding; GO:0045502 (0.01) ! dynein binding; GO:0044822 (0.01) ! poly(A) RNA binding; GO:0043565 (0.01) ! sequence-specific DNA binding; GO:0043130 (0.01) ! ubiquitin binding; GO:0042578 (0.01) ! phosphoric ester hydrolase activity; GO:0035091 (0.01) ! phosphatidylinositol binding; GO:0030898 (0.01) ! actin-dependent ATPase activity; GO:0030674 (0.01) ! protein binding, bridging; GO:0030165 (0.01) ! PDZ domain binding; GO:0030159 (0.01) ! receptor signaling complex scaffold activity; GO:0019894 (0.01) ! kinesin binding; GO:0017022 (0.01) ! myosin binding; GO:0016853 (0.01) ! isomerase activity; GO:0008565 (0.01) ! protein transporter activity; GO:0008432 (0.01) ! JUN kinase binding; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008134 (0.01) ! transcription factor binding; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005516 (0.01) ! calmodulin binding; GO:0005102 (0.01) ! receptor binding; GO:0005096 (0.01) ! GTPase activator activity; GO:0005078 (0.01) ! MAP-kinase scaffold activity; GO:0004872 (0.01) ! receptor activity; GO:0004702 (0.01) ! receptor signaling protein serine/threonine kinase activity; GO:0003700 (0.01) ! transcription factor activity, sequence-specific DNA binding; GO:0003682 (0.01) ! chromatin binding GO:0009987 (0.90) ! cellular process; GO:0044699 (0.83) ! single-organism process; GO:0044763 (0.80) ! single-organism cellular process; GO:0016043 (0.52) ! cellular component organization; GO:0006996 (0.44) ! organelle organization; GO:0022607 (0.37) ! cellular component assembly; GO:0007010 (0.36) ! cytoskeleton organization; GO:0070925 (0.33) ! organelle assembly; GO:0043933 (0.31) ! macromolecular complex subunit organization; GO:0043623 (0.30) ! cellular protein complex assembly; GO:0065007 (0.29) ! biological regulation; GO:0031106 (0.28) ! septin ring organization; GO:0050789 (0.27) ! regulation of biological process; GO:0007017 (0.27) ! microtubule-based process; GO:0051179 (0.26) ! localization; GO:0050794 (0.26) ! regulation of cellular process; GO:0006928 (0.26) ! movement of cell or subcellular component; GO:0051301 (0.24) ! cell division; GO:0051234 (0.23) ! establishment of localization; GO:0040016 (0.23) ! embryonic cleavage; GO:0007018 (0.20) ! microtubule-based movement; GO:0006810 (0.20) ! transport; GO:0032502 (0.19) ! developmental process; GO:0051641 (0.18) ! cellular localization; GO:0044767 (0.18) ! single-organism developmental process; GO:0051649 (0.17) ! establishment of localization in cell; GO:1902589 (0.13) ! single-organism organelle organization; GO:0051128 (0.13) ! regulation of cellular component organization; GO:0046907 (0.13) ! intracellular transport; GO:0048856 (0.12) ! anatomical structure development; GO:0048518 (0.12) ! positive regulation of biological process; GO:0048869 (0.11) ! cellular developmental process; GO:0048522 (0.11) ! positive regulation of cellular process; GO:0022402 (0.11) ! cell cycle process; GO:0008104 (0.11) ! protein localization; GO:0071704 (0.10) ! organic substance metabolic process; GO:0048519 (0.10) ! negative regulation of biological process; GO:0044238 (0.10) ! primary metabolic process; GO:0044237 (0.10) ! cellular metabolic process; GO:0032501 (0.10) ! multicellular organismal process; GO:1902578 (0.09) ! single-organism localization; GO:0080090 (0.09) ! regulation of primary metabolic process; GO:0060255 (0.09) ! regulation of macromolecule metabolic process; GO:0048523 (0.09) ! negative regulation of cellular process; GO:0044260 (0.09) ! cellular macromolecule metabolic process; GO:0033043 (0.09) ! regulation of organelle organization; GO:0031323 (0.09) ! regulation of cellular metabolic process; GO:0016192 (0.09) ! vesicle-mediated transport; GO:1903047 (0.08) ! mitotic cell cycle process; GO:0009653 (0.08) ! anatomical structure morphogenesis; GO:0065008 (0.07) ! regulation of biological quality; GO:0050896 (0.07) ! response to stimulus; GO:0050793 (0.07) ! regulation of developmental process; GO:0048583 (0.07) ! regulation of response to stimulus; GO:0044765 (0.07) ! single-organism transport; GO:0023051 (0.07) ! regulation of signaling; GO:0010646 (0.07) ! regulation of cell communication; GO:0071702 (0.06) ! organic substance transport; GO:0065009 (0.06) ! regulation of molecular function; GO:0051726 (0.06) ! regulation of cell cycle; GO:0051640 (0.06) ! organelle localization; GO:0051239 (0.06) ! regulation of multicellular organismal process; GO:0045184 (0.06) ! establishment of protein localization; GO:0044707 (0.06) ! single-multicellular organism process; GO:0044267 (0.06) ! cellular protein metabolic process; GO:0032879 (0.06) ! regulation of localization; GO:0032268 (0.06) ! regulation of cellular protein metabolic process; GO:0030705 (0.06) ! cytoskeleton-dependent intracellular transport; GO:0030029 (0.06) ! actin filament-based process; GO:0022414 (0.06) ! reproductive process; GO:0009966 (0.06) ! regulation of signal transduction; GO:0000226 (0.06) ! microtubule cytoskeleton organization; GO:2000026 (0.05) ! regulation of multicellular organismal development; GO:1902580 (0.05) ! single-organism cellular localization; GO:0051656 (0.05) ! establishment of organelle localization; GO:0051493 (0.05) ! regulation of cytoskeleton organization; GO:0050790 (0.05) ! regulation of catalytic activity; GO:0048646 (0.05) ! anatomical structure formation involved in morphogenesis; GO:0031325 (0.05) ! positive regulation of cellular metabolic process; GO:0030030 (0.05) ! cell projection organization; GO:0022603 (0.05) ! regulation of anatomical structure morphogenesis; GO:0015031 (0.05) ! protein transport; GO:0010604 (0.05) ! positive regulation of macromolecule metabolic process; GO:0007165 (0.05) ! signal transduction; GO:0006464 (0.05) ! cellular protein modification process; GO:0003008 (0.05) ! system process; GO:0061024 (0.04) ! membrane organization; GO:0060284 (0.04) ! regulation of cell development; GO:0051171 (0.04) ! regulation of nitrogen compound metabolic process; GO:0051130 (0.04) ! positive regulation of cellular component organization; GO:0051049 (0.04) ! regulation of transport; GO:0048585 (0.04) ! negative regulation of response to stimulus; GO:0048513 (0.04) ! animal organ development; GO:0048193 (0.04) ! Golgi vesicle transport; GO:0044702 (0.04) ! single organism reproductive process; GO:0044093 (0.04) ! positive regulation of molecular function; GO:0044087 (0.04) ! regulation of cellular component biogenesis; GO:0040011 (0.04) ! locomotion; GO:0034641 (0.04) ! cellular nitrogen compound metabolic process; GO:0032989 (0.04) ! cellular component morphogenesis; GO:0032270 (0.04) ! positive regulation of cellular protein metabolic process; GO:0031326 (0.04) ! regulation of cellular biosynthetic process; GO:0030154 (0.04) ! cell differentiation; GO:0030036 (0.04) ! actin cytoskeleton organization; GO:0022604 (0.04) ! regulation of cell morphogenesis; GO:0010564 (0.04) ! regulation of cell cycle process; GO:0010468 (0.04) ! regulation of gene expression; GO:0006886 (0.04) ! intracellular protein transport; GO:0001932 (0.04) ! regulation of protein phosphorylation; GO:1902582 (0.03) ! single-organism intracellular transport; GO:1902531 (0.03) ! regulation of intracellular signal transduction; GO:0090304 (0.03) ! nucleic acid metabolic process; GO:0060341 (0.03) ! regulation of cellular localization; GO:0051983 (0.03) ! regulation of chromosome segregation; GO:0051960 (0.03) ! regulation of nervous system development; GO:0051716 (0.03) ! cellular response to stimulus; GO:0051336 (0.03) ! regulation of hydrolase activity; GO:0051240 (0.03) ! positive regulation of multicellular organismal process; GO:0051094 (0.03) ! positive regulation of developmental process; GO:0048584 (0.03) ! positive regulation of response to stimulus; GO:0048468 (0.03) ! cell development; GO:0043085 (0.03) ! positive regulation of catalytic activity; GO:0034613 (0.03) ! cellular protein localization; GO:0033044 (0.03) ! regulation of chromosome organization; GO:0032956 (0.03) ! regulation of actin cytoskeleton organization; GO:0031344 (0.03) ! regulation of cell projection organization; GO:0016477 (0.03) ! cell migration; GO:0010927 (0.03) ! cellular component assembly involved in morphogenesis; GO:0010639 (0.03) ! negative regulation of organelle organization; GO:0009968 (0.03) ! negative regulation of signal transduction; GO:0009888 (0.03) ! tissue development; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0007411 (0.03) ! axon guidance; GO:0007088 (0.03) ! regulation of mitotic nuclear division; GO:0007033 (0.03) ! vacuole organization; GO:0006950 (0.03) ! response to stress; GO:0006796 (0.03) ! phosphate-containing compound metabolic process; GO:0006355 (0.03) ! regulation of transcription, DNA-templated; GO:0001934 (0.03) ! positive regulation of protein phosphorylation; GO:1903046 (0.02) ! meiotic cell cycle process; GO:1902533 (0.02) ! positive regulation of intracellular signal transduction; GO:0080134 (0.02) ! regulation of response to stress; GO:0072384 (0.02) ! organelle transport along microtubule; GO:0070507 (0.02) ! regulation of microtubule cytoskeleton organization; GO:0061640 (0.02) ! cytoskeleton-dependent cytokinesis; GO:0060627 (0.02) ! regulation of vesicle-mediated transport; GO:0051704 (0.02) ! multi-organism process; GO:0051650 (0.02) ! establishment of vesicle localization; GO:0051345 (0.02) ! positive regulation of hydrolase activity; GO:0051297 (0.02) ! centrosome organization; GO:0051294 (0.02) ! establishment of spindle orientation; GO:0051276 (0.02) ! chromosome organization; GO:0051270 (0.02) ! regulation of cellular component movement; GO:0051172 (0.02) ! negative regulation of nitrogen compound metabolic process; GO:0051050 (0.02) ! positive regulation of transport; GO:0048858 (0.02) ! cell projection morphogenesis; GO:0048729 (0.02) ! tissue morphogenesis; GO:0045859 (0.02) ! regulation of protein kinase activity; GO:0044802 (0.02) ! single-organism membrane organization; GO:0044782 (0.02) ! cilium organization; GO:0044710 (0.02) ! single-organism metabolic process; GO:0044708 (0.02) ! single-organism behavior; GO:0044271 (0.02) ! cellular nitrogen compound biosynthetic process; GO:0044089 (0.02) ! positive regulation of cellular component biogenesis; GO:0043087 (0.02) ! regulation of GTPase activity; GO:0042127 (0.02) ! regulation of cell proliferation; GO:0040012 (0.02) ! regulation of locomotion; GO:0040007 (0.02) ! growth; GO:0035556 (0.02) ! intracellular signal transduction; GO:0033554 (0.02) ! cellular response to stress; GO:0033365 (0.02) ! protein localization to organelle; GO:0033157 (0.02) ! regulation of intracellular protein transport; GO:0032940 (0.02) ! secretion by cell; GO:0032535 (0.02) ! regulation of cellular component size; GO:0031324 (0.02) ! negative regulation of cellular metabolic process; GO:0031032 (0.02) ! actomyosin structure organization; GO:0030855 (0.02) ! epithelial cell differentiation; GO:0030198 (0.02) ! extracellular matrix organization; GO:0030048 (0.02) ! actin filament-based movement; GO:0030031 (0.02) ! cell projection assembly; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0016070 (0.02) ! RNA metabolic process; GO:0010975 (0.02) ! regulation of neuron projection development; GO:0010941 (0.02) ! regulation of cell death; GO:0010769 (0.02) ! regulation of cell morphogenesis involved in differentiation; GO:0010720 (0.02) ! positive regulation of cell development; GO:0010638 (0.02) ! positive regulation of organelle organization; GO:0010628 (0.02) ! positive regulation of gene expression; GO:0010605 (0.02) ! negative regulation of macromolecule metabolic process; GO:0010033 (0.02) ! response to organic substance; GO:0009605 (0.02) ! response to external stimulus; GO:0009059 (0.02) ! macromolecule biosynthetic process; GO:0008360 (0.02) ! regulation of cell shape; GO:0007600 (0.02) ! sensory perception; GO:0007389 (0.02) ! pattern specification process; GO:0007166 (0.02) ! cell surface receptor signaling pathway; GO:0007163 (0.02) ! establishment or maintenance of cell polarity; GO:0007155 (0.02) ! cell adhesion; GO:0007154 (0.02) ! cell communication; GO:0007094 (0.02) ! mitotic spindle assembly checkpoint; GO:0007059 (0.02) ! chromosome segregation; GO:0007030 (0.02) ! Golgi organization; GO:0007020 (0.02) ! microtubule nucleation; GO:0006936 (0.02) ! muscle contraction; GO:0006913 (0.02) ! nucleocytoplasmic transport; GO:0006897 (0.02) ! endocytosis; GO:0006888 (0.02) ! ER to Golgi vesicle-mediated transport; GO:0006468 (0.02) ! protein phosphorylation; GO:0006357 (0.02) ! regulation of transcription from RNA polymerase II promoter; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0000902 (0.02) ! cell morphogenesis; GO:0000045 (0.02) ! autophagosome assembly; GO:2000027 (0.01) ! regulation of organ morphogenesis; GO:1903923 (0.01) ! positive regulation of protein processing in phagocytic vesicle; GO:1903919 (0.01) ! negative regulation of actin filament severing; GO:1903533 (0.01) ! regulation of protein targeting; GO:1903008 (0.01) ! organelle disassembly; GO:1902017 (0.01) ! regulation of cilium assembly; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:1901135 (0.01) ! carbohydrate derivative metabolic process; GO:0098930 (0.01) ! axonal transport; GO:0090630 (0.01) ! activation of GTPase activity; GO:0090316 (0.01) ! positive regulation of intracellular protein transport; GO:0090307 (0.01) ! mitotic spindle assembly; GO:0090306 (0.01) ! spindle assembly involved in meiosis; GO:0090305 (0.01) ! nucleic acid phosphodiester bond hydrolysis; GO:0090288 (0.01) ! negative regulation of cellular response to growth factor stimulus; GO:0090222 (0.01) ! centrosome-templated microtubule nucleation; GO:0090068 (0.01) ! positive regulation of cell cycle process; GO:0090002 (0.01) ! establishment of protein localization to plasma membrane; GO:0072659 (0.01) ! protein localization to plasma membrane; GO:0072521 (0.01) ! purine-containing compound metabolic process; GO:0071688 (0.01) ! striated muscle myosin thick filament assembly; GO:0071417 (0.01) ! cellular response to organonitrogen compound; GO:0061025 (0.01) ! membrane fusion; GO:0060429 (0.01) ! epithelium development; GO:0060317 (0.01) ! cardiac epithelial to mesenchymal transition; GO:0060271 (0.01) ! cilium morphogenesis; GO:0055086 (0.01) ! nucleobase-containing small molecule metabolic process; GO:0055059 (0.01) ! asymmetric neuroblast division; GO:0055013 (0.01) ! cardiac muscle cell development; GO:0051893 (0.01) ! regulation of focal adhesion assembly; GO:0051707 (0.01) ! response to other organism; GO:0051646 (0.01) ! mitochondrion localization; GO:0051642 (0.01) ! centrosome localization; GO:0051603 (0.01) ! proteolysis involved in cellular protein catabolic process; GO:0051496 (0.01) ! positive regulation of stress fiber assembly; GO:0051494 (0.01) ! negative regulation of cytoskeleton organization; GO:0051303 (0.01) ! establishment of chromosome localization; GO:0051302 (0.01) ! regulation of cell division; GO:0051259 (0.01) ! protein oligomerization; GO:0051241 (0.01) ! negative regulation of multicellular organismal process; GO:0051153 (0.01) ! regulation of striated muscle cell differentiation; GO:0051098 (0.01) ! regulation of binding; GO:0051093 (0.01) ! negative regulation of developmental process; GO:0051052 (0.01) ! regulation of DNA metabolic process; GO:0051051 (0.01) ! negative regulation of transport; GO:0050770 (0.01) ! regulation of axonogenesis; GO:0048878 (0.01) ! chemical homeostasis; GO:0048812 (0.01) ! neuron projection morphogenesis; GO:0048747 (0.01) ! muscle fiber development; GO:0048731 (0.01) ! system development; GO:0048638 (0.01) ! regulation of developmental growth; GO:0048598 (0.01) ! embryonic morphogenesis; GO:0048488 (0.01) ! synaptic vesicle endocytosis; GO:0048211 (0.01) ! Golgi vesicle docking; GO:0048167 (0.01) ! regulation of synaptic plasticity; GO:0047496 (0.01) ! vesicle transport along microtubule; GO:0046627 (0.01) ! negative regulation of insulin receptor signaling pathway; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045936 (0.01) ! negative regulation of phosphate metabolic process; GO:0045746 (0.01) ! negative regulation of Notch signaling pathway; GO:0045214 (0.01) ! sarcomere organization; GO:0045197 (0.01) ! establishment or maintenance of epithelial cell apical/basal polarity; GO:0045056 (0.01) ! transcytosis; GO:0045022 (0.01) ! early endosome to late endosome transport; GO:0044723 (0.01) ! single-organism carbohydrate metabolic process; GO:0044351 (0.01) ! macropinocytosis; GO:0044265 (0.01) ! cellular macromolecule catabolic process; GO:0043954 (0.01) ! cellular component maintenance; GO:0043254 (0.01) ! regulation of protein complex assembly; GO:0043086 (0.01) ! negative regulation of catalytic activity; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043009 (0.01) ! chordate embryonic development; GO:0042552 (0.01) ! myelination; GO:0042391 (0.01) ! regulation of membrane potential; GO:0042384 (0.01) ! cilium assembly; GO:0042246 (0.01) ! tissue regeneration; GO:0040019 (0.01) ! positive regulation of embryonic development; GO:0039689 (0.01) ! negative stranded viral RNA replication; GO:0035295 (0.01) ! tube development; GO:0035239 (0.01) ! tube morphogenesis; GO:0035107 (0.01) ! appendage morphogenesis; GO:0035082 (0.01) ! axoneme assembly; GO:0034976 (0.01) ! response to endoplasmic reticulum stress; GO:0034454 (0.01) ! microtubule anchoring at centrosome; GO:0034332 (0.01) ! adherens junction organization; GO:0033275 (0.01) ! actin-myosin filament sliding; GO:0032844 (0.01) ! regulation of homeostatic process; GO:0032507 (0.01) ! maintenance of protein location in cell; GO:0032506 (0.01) ! cytokinetic process; GO:0032269 (0.01) ! negative regulation of cellular protein metabolic process; GO:0032007 (0.01) ! negative regulation of TOR signaling; GO:0031589 (0.01) ! cell-substrate adhesion; GO:0031532 (0.01) ! actin cytoskeleton reorganization; GO:0031338 (0.01) ! regulation of vesicle fusion; GO:0031175 (0.01) ! neuron projection development; GO:0031122 (0.01) ! cytoplasmic microtubule organization; GO:0031110 (0.01) ! regulation of microtubule polymerization or depolymerization; GO:0030866 (0.01) ! cortical actin cytoskeleton organization; GO:0030335 (0.01) ! positive regulation of cell migration; GO:0030239 (0.01) ! myofibril assembly; GO:0030216 (0.01) ! keratinocyte differentiation; GO:0030182 (0.01) ! neuron differentiation; GO:0030111 (0.01) ! regulation of Wnt signaling pathway; GO:0030010 (0.01) ! establishment of cell polarity; GO:0022008 (0.01) ! neurogenesis; GO:0019637 (0.01) ! organophosphate metabolic process; GO:0019233 (0.01) ! sensory perception of pain; GO:0018193 (0.01) ! peptidyl-amino acid modification; GO:0018149 (0.01) ! peptide cross-linking; GO:0016567 (0.01) ! protein ubiquitination; GO:0016337 (0.01) ! single organismal cell-cell adhesion; GO:0016319 (0.01) ! mushroom body development; GO:0016236 (0.01) ! macroautophagy; GO:0016055 (0.01) ! Wnt signaling pathway; GO:0016050 (0.01) ! vesicle organization; GO:0016049 (0.01) ! cell growth; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0010976 (0.01) ! positive regulation of neuron projection development; GO:0010959 (0.01) ! regulation of metal ion transport; GO:0010824 (0.01) ! regulation of centrosome duplication; GO:0010811 (0.01) ! positive regulation of cell-substrate adhesion; GO:0010770 (0.01) ! positive regulation of cell morphogenesis involved in differentiation; GO:0010631 (0.01) ! epithelial cell migration; GO:0010506 (0.01) ! regulation of autophagy; GO:0010224 (0.01) ! response to UV-B; GO:0009887 (0.01) ! organ morphogenesis; GO:0009886 (0.01) ! post-embryonic morphogenesis; GO:0009880 (0.01) ! embryonic pattern specification; GO:0009798 (0.01) ! axis specification; GO:0009725 (0.01) ! response to hormone; GO:0009658 (0.01) ! chloroplast organization; GO:0009266 (0.01) ! response to temperature stimulus; GO:0008544 (0.01) ! epidermis development; GO:0008361 (0.01) ! regulation of cell size; GO:0008344 (0.01) ! adult locomotory behavior; GO:0008333 (0.01) ! endosome to lysosome transport; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008105 (0.01) ! asymmetric protein localization; GO:0008016 (0.01) ! regulation of heart contraction; GO:0007605 (0.01) ! sensory perception of sound; GO:0007528 (0.01) ! neuromuscular junction development; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007517 (0.01) ! muscle organ development; GO:0007507 (0.01) ! heart development; GO:0007420 (0.01) ! brain development; GO:0007416 (0.01) ! synapse assembly; GO:0007283 (0.01) ! spermatogenesis; GO:0007281 (0.01) ! germ cell development; GO:0007269 (0.01) ! neurotransmitter secretion; GO:0007268 (0.01) ! chemical synaptic transmission; GO:0007266 (0.01) ! Rho protein signal transduction; GO:0007257 (0.01) ! activation of JUN kinase activity; GO:0007169 (0.01) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007131 (0.01) ! reciprocal meiotic recombination; GO:0007100 (0.01) ! mitotic centrosome separation; GO:0007099 (0.01) ! centriole replication; GO:0007097 (0.01) ! nuclear migration; GO:0007067 (0.01) ! mitotic nuclear division; GO:0007062 (0.01) ! sister chromatid cohesion; GO:0007052 (0.01) ! mitotic spindle organization; GO:0007044 (0.01) ! cell-substrate junction assembly; GO:0007015 (0.01) ! actin filament organization; GO:0007005 (0.01) ! mitochondrion organization; GO:0006997 (0.01) ! nucleus organization; GO:0006974 (0.01) ! cellular response to DNA damage stimulus; GO:0006911 (0.01) ! phagocytosis, engulfment; GO:0006606 (0.01) ! protein import into nucleus; GO:0006457 (0.01) ! protein folding; GO:0006412 (0.01) ! translation; GO:0006405 (0.01) ! RNA export from nucleus; GO:0006325 (0.01) ! chromatin organization; GO:0006323 (0.01) ! DNA packaging; GO:0003341 (0.01) ! cilium movement; GO:0003009 (0.01) ! skeletal muscle contraction; GO:0002682 (0.01) ! regulation of immune system process; GO:0002376 (0.01) ! immune system process; GO:0002064 (0.01) ! epithelial cell development; GO:0002009 (0.01) ! morphogenesis of an epithelium; GO:0001822 (0.01) ! kidney development; GO:0001736 (0.01) ! establishment of planar polarity; GO:0001654 (0.01) ! eye development; GO:0001568 (0.01) ! blood vessel development; GO:0001558 (0.01) ! regulation of cell growth; GO:0001525 (0.01) ! angiogenesis; GO:0000301 (0.01) ! retrograde transport, vesicle recycling within Golgi; GO:0000281 (0.01) ! mitotic cytokinesis; GO:0000278 (0.01) ! mitotic cell cycle; GO:0000132 (0.01) ! establishment of mitotic spindle orientation; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter; GO:0000086 (0.01) ! G2/M transition of mitotic cell cycle; GO:0000070 (0.01) ! mitotic sister chromatid segregation; GO:0000022 (0.01) ! mitotic spindle elongation; GO:0000003 (0.01) ! reproduction GO:0044464 (1.00) ! cell part; GO:0044424 (0.99) ! intracellular part; GO:0044446 (0.89) ! intracellular organelle part; GO:0044430 (0.87) ! cytoskeletal part; GO:0043226 (0.87) ! organelle; GO:0043229 (0.86) ! intracellular organelle; GO:0044444 (0.85) ! cytoplasmic part; GO:0005737 (0.80) ! cytoplasm; GO:0032991 (0.65) ! macromolecular complex; GO:0043234 (0.64) ! protein complex; GO:0043232 (0.61) ! intracellular non-membrane-bounded organelle; GO:0016459 (0.54) ! myosin complex; GO:0016020 (0.49) ! membrane; GO:0043227 (0.41) ! membrane-bounded organelle; GO:0043231 (0.40) ! intracellular membrane-bounded organelle; GO:0044425 (0.33) ! membrane part; GO:0042995 (0.32) ! cell projection; GO:0032982 (0.31) ! myosin filament; GO:0031988 (0.30) ! membrane-bounded vesicle; GO:0005886 (0.29) ! plasma membrane; GO:0005856 (0.25) ! cytoskeleton; GO:0042641 (0.24) ! actomyosin; GO:0016023 (0.24) ! cytoplasmic, membrane-bounded vesicle; GO:0043292 (0.20) ! contractile fiber; GO:0030016 (0.19) ! myofibril; GO:0001725 (0.19) ! stress fiber; GO:0005634 (0.18) ! nucleus; GO:0099513 (0.17) ! polymeric cytoskeletal fiber; GO:0044421 (0.17) ! extracellular region part; GO:0005938 (0.17) ! cell cortex; GO:0044463 (0.16) ! cell projection part; GO:0044428 (0.16) ! nuclear part; GO:0031090 (0.16) ! organelle membrane; GO:0030139 (0.16) ! endocytic vesicle; GO:0016460 (0.16) ! myosin II complex; GO:0005829 (0.16) ! cytosol; GO:0070062 (0.15) ! extracellular exosome; GO:0044448 (0.15) ! cell cortex part; GO:0005794 (0.15) ! Golgi apparatus; GO:0044459 (0.14) ! plasma membrane part; GO:0005875 (0.14) ! microtubule associated complex; GO:0032155 (0.13) ! cell division site part; GO:0031252 (0.13) ! cell leading edge; GO:0005871 (0.13) ! kinesin complex; GO:0005773 (0.13) ! vacuole; GO:0001726 (0.13) ! ruffle; GO:0097458 (0.12) ! neuron part; GO:0032154 (0.12) ! cleavage furrow; GO:0031941 (0.12) ! filamentous actin; GO:0005903 (0.12) ! brush border; GO:0005884 (0.12) ! actin filament; GO:0044449 (0.11) ! contractile fiber part; GO:0005813 (0.11) ! centrosome; GO:0005654 (0.11) ! nucleoplasm; GO:0048471 (0.10) ! perinuclear region of cytoplasm; GO:0016021 (0.10) ! integral component of membrane; GO:0098589 (0.09) ! membrane region; GO:0098588 (0.09) ! bounding membrane of organelle; GO:0045335 (0.09) ! phagocytic vesicle; GO:0044431 (0.09) ! Golgi apparatus part; GO:0030054 (0.09) ! cell junction; GO:0030018 (0.09) ! Z disc; GO:0000331 (0.09) ! contractile vacuole; GO:1902494 (0.08) ! catalytic complex; GO:0098590 (0.08) ! plasma membrane region; GO:0005912 (0.08) ! adherens junction; GO:0005911 (0.08) ! cell-cell junction; GO:0061695 (0.07) ! transferase complex, transferring phosphorus-containing groups; GO:0031965 (0.07) ! nuclear membrane; GO:0030426 (0.07) ! growth cone; GO:0030424 (0.07) ! axon; GO:0030027 (0.07) ! lamellipodium; GO:0030017 (0.07) ! sarcomere; GO:0005913 (0.07) ! cell-cell adherens junction; GO:0005859 (0.07) ! muscle myosin complex; GO:0000139 (0.07) ! Golgi membrane; GO:0098858 (0.06) ! actin-based cell projection; GO:0098805 (0.06) ! whole membrane; GO:0097513 (0.06) ! myosin II filament; GO:0045334 (0.06) ! clathrin-coated endocytic vesicle; GO:0031253 (0.06) ! cell projection membrane; GO:0016591 (0.06) ! DNA-directed RNA polymerase II, holoenzyme; GO:0016328 (0.06) ! lateral plasma membrane; GO:0005940 (0.06) ! septin ring; GO:0005905 (0.06) ! clathrin-coated pit; GO:0044456 (0.05) ! synapse part; GO:0005819 (0.05) ! spindle; GO:0070160 (0.04) ! occluding junction; GO:0045202 (0.04) ! synapse; GO:0045179 (0.04) ! apical cortex; GO:0043025 (0.04) ! neuronal cell body; GO:0030496 (0.04) ! midbody; GO:0030141 (0.04) ! secretory granule; GO:0019898 (0.04) ! extrinsic component of membrane; GO:0015629 (0.04) ! actin cytoskeleton; GO:0005925 (0.04) ! focal adhesion; GO:0005874 (0.04) ! microtubule; GO:0005826 (0.04) ! actomyosin contractile ring; GO:0005774 (0.04) ! vacuolar membrane; GO:0005768 (0.04) ! endosome; GO:0005739 (0.04) ! mitochondrion; GO:0005730 (0.04) ! nucleolus; GO:0005643 (0.04) ! nuclear pore; GO:1990753 (0.03) ! equatorial cell cortex; GO:1990357 (0.03) ! terminal web; GO:0097433 (0.03) ! dense body; GO:0097204 (0.03) ! phagocytic cup base; GO:0090637 (0.03) ! inner dense plaque of desmosome; GO:0090636 (0.03) ! outer dense plaque of desmosome; GO:0071944 (0.03) ! cell periphery; GO:0060171 (0.03) ! stereocilium membrane; GO:0045160 (0.03) ! myosin I complex; GO:0045121 (0.03) ! membrane raft; GO:0044427 (0.03) ! chromosomal part; GO:0043209 (0.03) ! myelin sheath; GO:0043197 (0.03) ! dendritic spine; GO:0042383 (0.03) ! sarcolemma; GO:0032593 (0.03) ! insulin-responsive compartment; GO:0032588 (0.03) ! trans-Golgi network membrane; GO:0032587 (0.03) ! ruffle membrane; GO:0032420 (0.03) ! stereocilium; GO:0032009 (0.03) ! early phagosome; GO:0031594 (0.03) ! neuromuscular junction; GO:0031254 (0.03) ! cell trailing edge; GO:0031143 (0.03) ! pseudopodium; GO:0030486 (0.03) ! smooth muscle dense body; GO:0030175 (0.03) ! filopodium; GO:0010008 (0.03) ! endosome membrane; GO:0009925 (0.03) ! basal plasma membrane; GO:0005923 (0.03) ! bicellular tight junction; GO:0005915 (0.03) ! zonula adherens; GO:0005902 (0.03) ! microvillus; GO:0005769 (0.03) ! early endosome; GO:0005623 (0.03) ! cell; GO:0001931 (0.03) ! uropod; GO:0098791 (0.02) ! Golgi subcompartment; GO:0044441 (0.02) ! ciliary part; GO:0005814 (0.02) ! centriole; GO:0005783 (0.02) ! endoplasmic reticulum; GO:0000922 (0.02) ! spindle pole; GO:1990316 (0.01) ! ATG1/ULK1 kinase complex; GO:0098796 (0.01) ! membrane protein complex; GO:0098687 (0.01) ! chromosomal region; GO:0097539 (0.01) ! ciliary transition fiber; GO:0097431 (0.01) ! mitotic spindle pole; GO:0072686 (0.01) ! mitotic spindle; GO:0051233 (0.01) ! spindle midzone; GO:0048786 (0.01) ! presynaptic active zone; GO:0043256 (0.01) ! laminin complex; GO:0042734 (0.01) ! presynaptic membrane; GO:0036449 (0.01) ! microtubule minus-end; GO:0034451 (0.01) ! centriolar satellite; GO:0034045 (0.01) ! pre-autophagosomal structure membrane; GO:0033596 (0.01) ! TSC1-TSC2 complex; GO:0031985 (0.01) ! Golgi cisterna; GO:0031968 (0.01) ! organelle outer membrane; GO:0031012 (0.01) ! extracellular matrix; GO:0030529 (0.01) ! intracellular ribonucleoprotein complex; GO:0030133 (0.01) ! transport vesicle; GO:0015630 (0.01) ! microtubule cytoskeleton; GO:0012507 (0.01) ! ER to Golgi transport vesicle membrane; GO:0012505 (0.01) ! endomembrane system; GO:0005930 (0.01) ! axoneme; GO:0005929 (0.01) ! cilium; GO:0005881 (0.01) ! cytoplasmic microtubule; GO:0005876 (0.01) ! spindle microtubule; GO:0005801 (0.01) ! cis-Golgi network; GO:0005795 (0.01) ! Golgi stack; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005694 (0.01) ! chromosome; GO:0005635 (0.01) ! nuclear envelope; GO:0005622 (0.01) ! intracellular; GO:0005615 (0.01) ! extracellular space; GO:0005604 (0.01) ! basement membrane; GO:0005576 (0.01) ! extracellular region; GO:0000795 (0.01) ! synaptonemal complex; GO:0000785 (0.01) ! chromatin; GO:0000776 (0.01) ! kinetochore; GO:0000421 (0.01) ! autophagosome membrane; GO:0000242 (0.01) ! pericentriolar material; GO:0000151 (0.01) ! ubiquitin ligase complex GO:0005515 ! protein binding 3 GO:0005515 ! protein binding 74987632-75005800 (17q25.1) High: cerebellum (cells in granular layer; Purkinje cells);placenta (decidual cells);small intestine (glandular cells);tonsil (germinal center cells; squamous epithelial cells);appendix (glandular cells; lymphoid tissue);gallbladder (glandular cells);stomach 2 (glandular cells);esophagus (squamous epithelial cells);rectum (glandular cells);cervix, uterine (squamous epithelial cells);duodenum (glandular cells);Medium: stomach 1 (glandular cells);colon (glandular cells; peripheral nerve/ganglion);kidney (cells in tubules);testis (cells in seminiferous ducts);caudate (neuronal cells);tonsil (non-germinal center cells);thyroid gland (glandular cells);adrenal gland (glandular cells);endometrium 1 (glandular cells);endometrium 2 (glandular cells);vagina (squamous epithelial cells);cerebral cortex (neuropil);lymph node (germinal center cells; non-germinal center cells);placenta (trophoblastic cells);hippocampus (neuronal cells);bronchus (respiratory epithelial cells);parathyroid gland (glandular cells);urinary bladder (urothelial cells);breast (glandular cells; myoepithelial cells);prostate (glandular cells);pancreas (exocrine glandular cells; islets of Langerhans);cerebellum (cells in molecular layer);fallopian tube (glandular cells);spleen (cells in red pulp);bone marrow (hematopoietic cells);soft tissue 2 (fibroblasts);soft tissue 1 (fibroblasts);nasopharynx (respiratory epithelial cells);lung (macrophages);oral mucosa (squamous epithelial cells);skin 1 (fibroblasts; keratinocytes; melanocytes);skin 2 (epidermal cells);Low: testis (Leydig cells);caudate (glial cells);spleen (cells in white pulp);skin 1 (Langerhans);skeletal muscle (myocytes);endometrium 1 (cells in endometrial stroma);salivary gland (glandular cells);colon (endothelial cells);heart muscle (myocytes);smooth muscle (smooth muscle cells);soft tissue 1 (adipocytes);seminal vesicle (glandular cells);lung (pneumocytes);ovary (ovarian stroma cells);cerebral cortex (endothelial cells);kidney (cells in glomeruli);liver (hepatocytes); Brain - Cerebellum: 128.70; Brain - Cerebellar Hemisphere: 119.50; Brain - Spinal cord (cervical c-1): 55.35; Cells - Transformed fibroblasts: 30.72; Lung: 27.12; Artery - Aorta: 26.23; Cervix - Ectocervix: 24.84; Uterus: 24.66; Artery - Tibial: 23.05; Cervix - Endocervix: 22.42; Artery - Coronary: 22.34; Stomach: 21.27; Esophagus - Gastroesophageal Junction: 20.80; Brain - Substantia nigra: 20.39; Colon - Sigmoid: 19.69; Testis: 19.44; Esophagus - Muscularis: 18.70; Bladder: 16.37; Fallopian Tube: 16.36; Adipose - Visceral (Omentum): 16.01; Breast - Mammary Tissue: 15.65; Brain - Hippocampus: 15.36; Prostate: 15.24; Vagina: 14.93; Nerve - Tibial: 14.40; Small Intestine - Terminal Ileum: 14.21; Brain - Hypothalamus: 13.67; Minor Salivary Gland: 13.59; Adipose - Subcutaneous: 13.57; Brain - Putamen (basal ganglia): 12.48; Brain - Frontal Cortex (BA9): 12.43; Brain - Cortex: 12.40; Kidney - Cortex: 12.40; Pituitary: 11.90; Heart - Atrial Appendage: 11.76; Heart - Left Ventricle: 11.31; Thyroid: 10.75; Brain - Caudate (basal ganglia): 9.86; Esophagus - Mucosa: 9.73; Colon - Transverse: 8.81; Brain - Amygdala: 8.51; Skin - Sun Exposed (Lower leg): 8.37; Adrenal Gland: 8.00; Skin - Not Sun Exposed (Suprapubic): 7.06; Brain - Anterior cingulate cortex (BA24): 7.05; Brain - Nucleus accumbens (basal ganglia): 6.85; Ovary: 6.15; Spleen: 3.16; Pancreas: 2.93; Muscle - Skeletal: 1.54; Liver: 1.01; Whole Blood: 0.19; Cells - EBV-transformed lymphocytes: 0.12; MRRAAGMEDFSAEEEESWYDQQDLEQDLHLAAELGKTLLERNKELEGSLQQMYSTNEEQVQEIEYLTKQLDTLRHVNEQHAKVYEQLDLTARDLELTNHRLVLESKAAQQKIHGLTETIERLQAQVEELQAQVEQLRGLEQLRVLREKRERRRTIHTFPCLKELCTSPRCKDAFRLHSSSLELGPRPLEQENERLQTLVGALRSQVSQERQRKERAEREYTAVLQEYSELERQLCEMEACRLRVQELEAELLELQQMKQAKTYLLGPDDHLAEALLAPLTQAPEADDPQPGRGDDLGAQDGVSSPAASPGHVVRKSCSDTALNAIVAKDPASRHAGNLTLHANSVRKRGMSILREVDEQYHALLEKYEELLSKCRQHGAGVRHAGVQTSRPISRDSSWRDLRGGEEGQGEVKAGEKSLSQHVEAVDKRLEQSQPEYKALFKEIFSRIQKTKADINATKVKTHSSK TMEM94 Transmembrane protein 94 TMM94_HUMAN (Q12767-1) GO:0043492 (0.91) ! ATPase activity, coupled to movement of substances; GO:0022892 (0.91) ! substrate-specific transporter activity; GO:0019829 (0.74) ! cation-transporting ATPase activity; GO:0022890 (0.61) ! inorganic cation transmembrane transporter activity; GO:0015662 (0.61) ! ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; GO:0046873 (0.57) ! metal ion transmembrane transporter activity; GO:0015077 (0.41) ! monovalent inorganic cation transmembrane transporter activity; GO:0005524 (0.37) ! ATP binding; GO:0005391 (0.37) ! sodium:potassium-exchanging ATPase activity; GO:0046872 (0.29) ! metal ion binding; GO:0031420 (0.28) ! alkali metal ion binding; GO:0019899 (0.28) ! enzyme binding; GO:0072509 (0.24) ! divalent inorganic cation transmembrane transporter activity; GO:0004012 (0.24) ! phospholipid-translocating ATPase activity; GO:0005388 (0.23) ! calcium-transporting ATPase activity; GO:0015078 (0.09) ! hydrogen ion transmembrane transporter activity; GO:0046915 (0.08) ! transition metal ion transmembrane transporter activity; GO:0008553 (0.06) ! hydrogen-exporting ATPase activity, phosphorylative mechanism; GO:0043682 (0.04) ! copper-transporting ATPase activity; GO:0030165 (0.04) ! PDZ domain binding; GO:0015410 (0.04) ! manganese-transporting ATPase activity; GO:0008900 (0.03) ! hydrogen:potassium-exchanging ATPase activity; GO:0086039 (0.01) ! calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential; GO:0051087 (0.01) ! chaperone binding; GO:0046914 (0.01) ! transition metal ion binding; GO:0015086 (0.01) ! cadmium ion transmembrane transporter activity; GO:0005516 (0.01) ! calmodulin binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005385 (0.01) ! zinc ion transmembrane transporter activity; GO:0004008 (0.01) ! copper-exporting ATPase activity GO:0009987 (0.90) ! cellular process; GO:0044699 (0.85) ! single-organism process; GO:0044763 (0.84) ! single-organism cellular process; GO:0065007 (0.81) ! biological regulation; GO:0065008 (0.80) ! regulation of biological quality; GO:0098771 (0.77) ! inorganic ion homeostasis; GO:0030003 (0.77) ! cellular cation homeostasis; GO:0006875 (0.72) ! cellular metal ion homeostasis; GO:0006810 (0.71) ! transport; GO:0006812 (0.68) ! cation transport; GO:0034220 (0.66) ! ion transmembrane transport; GO:0098662 (0.65) ! inorganic cation transmembrane transport; GO:1902600 (0.64) ! hydrogen ion transmembrane transport; GO:0090662 (0.60) ! ATP hydrolysis coupled transmembrane transport; GO:0015988 (0.60) ! energy coupled proton transmembrane transport, against electrochemical gradient; GO:0030004 (0.57) ! cellular monovalent inorganic cation homeostasis; GO:0030001 (0.56) ! metal ion transport; GO:0071805 (0.52) ! potassium ion transmembrane transport; GO:0071436 (0.52) ! sodium ion export; GO:0055078 (0.52) ! sodium ion homeostasis; GO:0055075 (0.52) ! potassium ion homeostasis; GO:0006874 (0.35) ! cellular calcium ion homeostasis; GO:0050789 (0.34) ! regulation of biological process; GO:0032879 (0.31) ! regulation of localization; GO:0098657 (0.29) ! import into cell; GO:0042391 (0.29) ! regulation of membrane potential; GO:0010959 (0.29) ! regulation of metal ion transport; GO:0098739 (0.28) ! import across plasma membrane; GO:0010248 (0.28) ! establishment or maintenance of transmembrane electrochemical gradient; GO:0016043 (0.21) ! cellular component organization; GO:0006996 (0.17) ! organelle organization; GO:0036376 (0.15) ! sodium ion export from cell; GO:0030007 (0.15) ! cellular potassium ion homeostasis; GO:0015991 (0.15) ! ATP hydrolysis coupled proton transport; GO:0010107 (0.15) ! potassium ion import; GO:0006883 (0.15) ! cellular sodium ion homeostasis; GO:0061024 (0.14) ! membrane organization; GO:0048194 (0.10) ! Golgi vesicle budding; GO:0051453 (0.08) ! regulation of intracellular pH; GO:0050896 (0.07) ! response to stimulus; GO:0032502 (0.06) ! developmental process; GO:0007030 (0.06) ! Golgi organization; GO:0097035 (0.05) ! regulation of membrane lipid distribution; GO:0050794 (0.05) ! regulation of cellular process; GO:0048856 (0.05) ! anatomical structure development; GO:0044767 (0.05) ! single-organism developmental process; GO:0015914 (0.05) ! phospholipid transport; GO:0006816 (0.05) ! calcium ion transport; GO:0045332 (0.04) ! phospholipid translocation; GO:0042221 (0.04) ! response to chemical; GO:0032501 (0.04) ! multicellular organismal process; GO:0051716 (0.03) ! cellular response to stimulus; GO:0051480 (0.03) ! regulation of cytosolic calcium ion concentration; GO:0048518 (0.03) ! positive regulation of biological process; GO:0044057 (0.03) ! regulation of system process; GO:0016192 (0.03) ! vesicle-mediated transport; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0006950 (0.03) ! response to stress; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:0070887 (0.02) ! cellular response to chemical stimulus; GO:0048869 (0.02) ! cellular developmental process; GO:0048519 (0.02) ! negative regulation of biological process; GO:0048193 (0.02) ! Golgi vesicle transport; GO:0046916 (0.02) ! cellular transition metal ion homeostasis; GO:0044707 (0.02) ! single-multicellular organism process; GO:0044237 (0.02) ! cellular metabolic process; GO:0040011 (0.02) ! locomotion; GO:0035556 (0.02) ! intracellular signal transduction; GO:0023051 (0.02) ! regulation of signaling; GO:0009888 (0.02) ! tissue development; GO:0009725 (0.02) ! response to hormone; GO:0009653 (0.02) ! anatomical structure morphogenesis; GO:0008016 (0.02) ! regulation of heart contraction; GO:0006942 (0.02) ! regulation of striated muscle contraction; GO:0006897 (0.02) ! endocytosis; GO:0003008 (0.02) ! system process; GO:0000041 (0.02) ! transition metal ion transport; GO:1903779 (0.01) ! regulation of cardiac conduction; GO:1903416 (0.01) ! response to glycoside; GO:1902531 (0.01) ! regulation of intracellular signal transduction; GO:0099402 (0.01) ! plant organ development; GO:0098609 (0.01) ! cell-cell adhesion; GO:0090066 (0.01) ! regulation of anatomical structure size; GO:0086009 (0.01) ! membrane repolarization; GO:0080090 (0.01) ! regulation of primary metabolic process; GO:0071383 (0.01) ! cellular response to steroid hormone stimulus; GO:0070588 (0.01) ! calcium ion transmembrane transport; GO:0070509 (0.01) ! calcium ion import; GO:0060627 (0.01) ! regulation of vesicle-mediated transport; GO:0060416 (0.01) ! response to growth hormone; GO:0060255 (0.01) ! regulation of macromolecule metabolic process; GO:0060048 (0.01) ! cardiac muscle contraction; GO:0060003 (0.01) ! copper ion export; GO:0055119 (0.01) ! relaxation of cardiac muscle; GO:0051208 (0.01) ! sequestering of calcium ion; GO:0051128 (0.01) ! regulation of cellular component organization; GO:0051050 (0.01) ! positive regulation of transport; GO:0050911 (0.01) ! detection of chemical stimulus involved in sensory perception of smell; GO:0050790 (0.01) ! regulation of catalytic activity; GO:0048840 (0.01) ! otolith development; GO:0048666 (0.01) ! neuron development; GO:0048523 (0.01) ! negative regulation of cellular process; GO:0048522 (0.01) ! positive regulation of cellular process; GO:0045988 (0.01) ! negative regulation of striated muscle contraction; GO:0044702 (0.01) ! single organism reproductive process; GO:0044351 (0.01) ! macropinocytosis; GO:0042538 (0.01) ! hyperosmotic salinity response; GO:0042493 (0.01) ! response to drug; GO:0042044 (0.01) ! fluid transport; GO:0040012 (0.01) ! regulation of locomotion; GO:0035050 (0.01) ! embryonic heart tube development; GO:0034976 (0.01) ! response to endoplasmic reticulum stress; GO:0032880 (0.01) ! regulation of protein localization; GO:0032472 (0.01) ! Golgi calcium ion transport; GO:0031448 (0.01) ! positive regulation of fast-twitch skeletal muscle fiber contraction; GO:0031323 (0.01) ! regulation of cellular metabolic process; GO:0030317 (0.01) ! sperm motility; GO:0030154 (0.01) ! cell differentiation; GO:0030026 (0.01) ! cellular manganese ion homeostasis; GO:0021591 (0.01) ! ventricular system development; GO:0016049 (0.01) ! cell growth; GO:0010882 (0.01) ! regulation of cardiac muscle contraction by calcium ion signaling; GO:0010042 (0.01) ! response to manganese ion; GO:0009887 (0.01) ! organ morphogenesis; GO:0009792 (0.01) ! embryo development ending in birth or egg hatching; GO:0009612 (0.01) ! response to mechanical stimulus; GO:0009117 (0.01) ! nucleotide metabolic process; GO:0008544 (0.01) ! epidermis development; GO:0007626 (0.01) ! locomotory behavior; GO:0007605 (0.01) ! sensory perception of sound; GO:0007507 (0.01) ! heart development; GO:0007423 (0.01) ! sensory organ development; GO:0007420 (0.01) ! brain development; GO:0007368 (0.01) ! determination of left/right symmetry; GO:0007154 (0.01) ! cell communication; GO:0006890 (0.01) ! retrograde vesicle-mediated transport, Golgi to ER; GO:0006886 (0.01) ! intracellular protein transport; GO:0006878 (0.01) ! cellular copper ion homeostasis; GO:0006828 (0.01) ! manganese ion transport; GO:0006091 (0.01) ! generation of precursor metabolites and energy; GO:0002119 (0.01) ! nematode larval development; GO:0002028 (0.01) ! regulation of sodium ion transport; GO:0001947 (0.01) ! heart looping GO:0005654 (1.00) ! nucleoplasm GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 75441159-75500090 (17q25.1) High: cerebellum (cells in molecular layer);hippocampus (glial cells);liver (hepatocytes);bronchus (respiratory epithelial cells);urinary bladder (urothelial cells);small intestine (glandular cells);colon (glandular cells);gallbladder (glandular cells);lung (macrophages);cerebral cortex (glial cells; neuropil);kidney (cells in tubules);duodenum (glandular cells);Medium: cerebellum (cells in granular layer);stomach 2 (glandular cells);stomach 1 (glandular cells);caudate (glial cells);seminal vesicle (glandular cells);parathyroid gland (glandular cells);thyroid gland (glandular cells);adrenal gland (glandular cells);salivary gland (glandular cells);endometrium 2 (glandular cells);appendix (glandular cells);heart muscle (myocytes);nasopharynx (respiratory epithelial cells);rectum (glandular cells);Low: placenta (trophoblastic cells);testis (Leydig cells);caudate (neuronal cells);soft tissue 2 (fibroblasts);tonsil (non-germinal center cells; squamous epithelial cells);liver (bile duct cells);skeletal muscle (myocytes);epididymis (glandular cells);colon (peripheral nerve/ganglion);cervix, uterine (glandular cells);pancreas (exocrine glandular cells);kidney (cells in glomeruli);breast (glandular cells); MDLKEKHLGEPPSALGLSTRKALSVLKEQLEAVLEGHLRERKKCLTWKEVWRSSFLHHSNRCSCFHWPGASLMLLAVLLLLGCCGGQPAGSRGVGLVNASALFLLLLLNLVLIGRQDRLKRREVERRLRGIIDQIQDALRDGREIQWPSAMYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVERGPQSPQQHRLFRVLETPVIDNIRWCLDMALSRPVTALDNERFTVQSVMLHYAVPVVLAGFLITNALRFIFSAPGVTSWQYTLLQLQVNGVLPILPLLFPVLWVLATACGEARVLAQMSKASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVLGGTSPTLSHSSSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLTDGLSTRSFCHPEPHERDALLAGSLNNTLHLSNEQERGDWPGEAPKPPEPYSHHKAHGRSKHPSGSNVSFSRDTEGGEEEPSKTQPGMESDPYEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQLHLTSLKPLGLNVLLNLCDASVTERLCRFSDHLCNIALQESHSAVLPVHVPWGLCELARLIGFTPGAKELFKQENHLALYRLPSAETMKETSLGRLSCVTKRRPPLSHMISLFIKDTTTSTEQMLSHGTADVVLEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMNCALSSQLNGKCIELVQVPGQSSIFTMCELPSTIPIKQNARRSSWSSDEGIGEVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELKSKVFAEKMGLETGWNCHISLTPNGDMPGSEIPPSSPSHAGSLHDDLNQVSRDDAEGLLLMEEEGHSDLISFQPTDSDIPSFLEDSNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDISIALDPLYPSRCSWETFGYATSISMAQASDGLSPLQLSGQLNSLPCSLTFRQEETISIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSIMSMATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLICFGFTLQSFCDSSRDRNLTNCSSVMLPSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISITHVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTAVDLQLWTHRDSHVHFGLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF CASKIN2 Caskin-2 CSKI2_HUMAN (Q8WXE0-1) GO:0003824 (0.44) ! catalytic activity; GO:0016740 (0.39) ! transferase activity; GO:0019899 (0.31) ! enzyme binding; GO:0004842 (0.25) ! ubiquitin-protein transferase activity; GO:0008092 (0.21) ! cytoskeletal protein binding; GO:1901363 (0.18) ! heterocyclic compound binding; GO:0097159 (0.18) ! organic cyclic compound binding; GO:0031625 (0.18) ! ubiquitin protein ligase binding; GO:0030507 (0.15) ! spectrin binding; GO:0008093 (0.15) ! cytoskeletal adaptor activity; GO:0016773 (0.14) ! phosphotransferase activity, alcohol group as acceptor; GO:0016301 (0.14) ! kinase activity; GO:0005215 (0.14) ! transporter activity; GO:0003676 (0.14) ! nucleic acid binding; GO:0008324 (0.13) ! cation transmembrane transporter activity; GO:0005216 (0.13) ! ion channel activity; GO:0005198 (0.13) ! structural molecule activity; GO:0004672 (0.13) ! protein kinase activity; GO:0046873 (0.12) ! metal ion transmembrane transporter activity; GO:0005261 (0.12) ! cation channel activity; GO:0005262 (0.10) ! calcium channel activity; GO:0046872 (0.09) ! metal ion binding; GO:0044877 (0.09) ! macromolecular complex binding; GO:0016787 (0.09) ! hydrolase activity; GO:0005524 (0.09) ! ATP binding; GO:0005200 (0.09) ! structural constituent of cytoskeleton; GO:0051117 (0.08) ! ATPase binding; GO:0022836 (0.08) ! gated channel activity; GO:0003723 (0.08) ! RNA binding; GO:0019901 (0.07) ! protein kinase binding; GO:0098772 (0.06) ! molecular function regulator; GO:0044325 (0.06) ! ion channel binding; GO:0016788 (0.06) ! hydrolase activity, acting on ester bonds; GO:0003677 (0.06) ! DNA binding; GO:0000989 (0.06) ! transcription factor activity, transcription factor binding; GO:0003712 (0.05) ! transcription cofactor activity; GO:0003700 (0.05) ! transcription factor activity, sequence-specific DNA binding; GO:0043565 (0.04) ! sequence-specific DNA binding; GO:0043021 (0.04) ! ribonucleoprotein complex binding; GO:0030234 (0.04) ! enzyme regulator activity; GO:0019843 (0.04) ! rRNA binding; GO:0005516 (0.04) ! calmodulin binding; GO:0005227 (0.04) ! calcium activated cation channel activity; GO:0004674 (0.04) ! protein serine/threonine kinase activity; GO:0004521 (0.04) ! endoribonuclease activity; GO:0044822 (0.03) ! poly(A) RNA binding; GO:0044212 (0.03) ! transcription regulatory region DNA binding; GO:0022843 (0.03) ! voltage-gated cation channel activity; GO:0019904 (0.03) ! protein domain specific binding; GO:0017016 (0.03) ! Ras GTPase binding; GO:0008134 (0.03) ! transcription factor binding; GO:0005102 (0.03) ! receptor binding; GO:0004871 (0.03) ! signal transducer activity; GO:0003682 (0.03) ! chromatin binding; GO:0000981 (0.03) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0099600 (0.02) ! transmembrane receptor activity; GO:0050839 (0.02) ! cell adhesion molecule binding; GO:0042802 (0.02) ! identical protein binding; GO:0042393 (0.02) ! histone binding; GO:0032403 (0.02) ! protein complex binding; GO:0031432 (0.02) ! titin binding; GO:0030165 (0.02) ! PDZ domain binding; GO:0019887 (0.02) ! protein kinase regulator activity; GO:0017137 (0.02) ! Rab GTPase binding; GO:0015279 (0.02) ! store-operated calcium channel activity; GO:0008289 (0.02) ! lipid binding; GO:0008017 (0.02) ! microtubule binding; GO:0005249 (0.02) ! voltage-gated potassium channel activity; GO:0005085 (0.02) ! guanyl-nucleotide exchange factor activity; GO:0003779 (0.02) ! actin binding; GO:0003713 (0.02) ! transcription coactivator activity; GO:0002039 (0.02) ! p53 binding; GO:0000977 (0.02) ! RNA polymerase II regulatory region sequence-specific DNA binding; GO:1901981 (0.01) ! phosphatidylinositol phosphate binding; GO:0070011 (0.01) ! peptidase activity, acting on L-amino acid peptides; GO:0061630 (0.01) ! ubiquitin protein ligase activity; GO:0051427 (0.01) ! hormone receptor binding; GO:0051015 (0.01) ! actin filament binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0042803 (0.01) ! protein homodimerization activity; GO:0042623 (0.01) ! ATPase activity, coupled; GO:0042578 (0.01) ! phosphoric ester hydrolase activity; GO:0035064 (0.01) ! methylated histone binding; GO:0030374 (0.01) ! ligand-dependent nuclear receptor transcription coactivator activity; GO:0019903 (0.01) ! protein phosphatase binding; GO:0019208 (0.01) ! phosphatase regulator activity; GO:0018024 (0.01) ! histone-lysine N-methyltransferase activity; GO:0017124 (0.01) ! SH3 domain binding; GO:0017056 (0.01) ! structural constituent of nuclear pore; GO:0016779 (0.01) ! nucleotidyltransferase activity; GO:0016409 (0.01) ! palmitoyltransferase activity; GO:0015276 (0.01) ! ligand-gated ion channel activity; GO:0008381 (0.01) ! mechanically-gated ion channel activity; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008270 (0.01) ! zinc ion binding; GO:0008190 (0.01) ! eukaryotic initiation factor 4E binding; GO:0008139 (0.01) ! nuclear localization sequence binding; GO:0008022 (0.01) ! protein C-terminus binding; GO:0008013 (0.01) ! beta-catenin binding; GO:0005487 (0.01) ! nucleocytoplasmic transporter activity; GO:0005201 (0.01) ! extracellular matrix structural constituent; GO:0005096 (0.01) ! GTPase activator activity; GO:0004888 (0.01) ! transmembrane signaling receptor activity; GO:0004857 (0.01) ! enzyme inhibitor activity; GO:0004713 (0.01) ! protein tyrosine kinase activity; GO:0004702 (0.01) ! receptor signaling protein serine/threonine kinase activity; GO:0004359 (0.01) ! glutaminase activity; GO:0003714 (0.01) ! transcription corepressor activity; GO:0001104 (0.01) ! RNA polymerase II transcription cofactor activity; GO:0001077 (0.01) ! transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0000149 (0.01) ! SNARE binding GO:0065007 (0.71) ! biological regulation; GO:0050789 (0.66) ! regulation of biological process; GO:0050794 (0.65) ! regulation of cellular process; GO:0009987 (0.42) ! cellular process; GO:0007165 (0.41) ! signal transduction; GO:0044699 (0.36) ! single-organism process; GO:0044763 (0.27) ! single-organism cellular process; GO:0016043 (0.24) ! cellular component organization; GO:0080090 (0.18) ! regulation of primary metabolic process; GO:0060255 (0.18) ! regulation of macromolecule metabolic process; GO:0051179 (0.18) ! localization; GO:0044767 (0.18) ! single-organism developmental process; GO:0044237 (0.17) ! cellular metabolic process; GO:0031323 (0.17) ! regulation of cellular metabolic process; GO:0071704 (0.16) ! organic substance metabolic process; GO:0044238 (0.16) ! primary metabolic process; GO:0048523 (0.15) ! negative regulation of cellular process; GO:0048518 (0.15) ! positive regulation of biological process; GO:0043170 (0.15) ! macromolecule metabolic process; GO:0006810 (0.15) ! transport; GO:0048522 (0.14) ! positive regulation of cellular process; GO:0044260 (0.14) ! cellular macromolecule metabolic process; GO:0023051 (0.14) ! regulation of signaling; GO:0010646 (0.14) ! regulation of cell communication; GO:0050896 (0.13) ! response to stimulus; GO:0043412 (0.13) ! macromolecule modification; GO:0051171 (0.12) ! regulation of nitrogen compound metabolic process; GO:0048583 (0.12) ! regulation of response to stimulus; GO:0019538 (0.12) ! protein metabolic process; GO:2000112 (0.11) ! regulation of cellular macromolecule biosynthetic process; GO:0051641 (0.11) ! cellular localization; GO:0019219 (0.11) ! regulation of nucleobase-containing compound metabolic process; GO:0010468 (0.11) ! regulation of gene expression; GO:0006464 (0.11) ! cellular protein modification process; GO:1902578 (0.10) ! single-organism localization; GO:0065008 (0.10) ! regulation of biological quality; GO:0051239 (0.10) ! regulation of multicellular organismal process; GO:0048869 (0.10) ! cellular developmental process; GO:0048856 (0.10) ! anatomical structure development; GO:0046907 (0.10) ! intracellular transport; GO:0032501 (0.10) ! multicellular organismal process; GO:0009966 (0.10) ! regulation of signal transduction; GO:0009653 (0.10) ! anatomical structure morphogenesis; GO:0008104 (0.10) ! protein localization; GO:0006355 (0.10) ! regulation of transcription, DNA-templated; GO:0071702 (0.09) ! organic substance transport; GO:0045184 (0.09) ! establishment of protein localization; GO:0044765 (0.09) ! single-organism transport; GO:0044707 (0.09) ! single-multicellular organism process; GO:0034613 (0.09) ! cellular protein localization; GO:0072657 (0.08) ! protein localization to membrane; GO:0065009 (0.08) ! regulation of molecular function; GO:0051246 (0.08) ! regulation of protein metabolic process; GO:0051128 (0.08) ! regulation of cellular component organization; GO:0010604 (0.08) ! positive regulation of macromolecule metabolic process; GO:0006950 (0.08) ! response to stress; GO:0006886 (0.08) ! intracellular protein transport; GO:0006796 (0.08) ! phosphate-containing compound metabolic process; GO:0006357 (0.08) ! regulation of transcription from RNA polymerase II promoter; GO:2000026 (0.07) ! regulation of multicellular organismal development; GO:0072661 (0.07) ! protein targeting to plasma membrane; GO:0032879 (0.07) ! regulation of localization; GO:0031399 (0.07) ! regulation of protein modification process; GO:0031325 (0.07) ! positive regulation of cellular metabolic process; GO:0007166 (0.07) ! cell surface receptor signaling pathway; GO:0006996 (0.07) ! organelle organization; GO:1902531 (0.06) ! regulation of intracellular signal transduction; GO:0051172 (0.06) ! negative regulation of nitrogen compound metabolic process; GO:0050790 (0.06) ! regulation of catalytic activity; GO:0048584 (0.06) ! positive regulation of response to stimulus; GO:0042221 (0.06) ! response to chemical; GO:0035556 (0.06) ! intracellular signal transduction; GO:0032989 (0.06) ! cellular component morphogenesis; GO:0031324 (0.06) ! negative regulation of cellular metabolic process; GO:0030030 (0.06) ! cell projection organization; GO:0023057 (0.06) ! negative regulation of signaling; GO:0010648 (0.06) ! negative regulation of cell communication; GO:0010647 (0.06) ! positive regulation of cell communication; GO:0010605 (0.06) ! negative regulation of macromolecule metabolic process; GO:0006952 (0.06) ! defense response; GO:0006468 (0.06) ! protein phosphorylation; GO:0002376 (0.06) ! immune system process; GO:0051960 (0.05) ! regulation of nervous system development; GO:0051716 (0.05) ! cellular response to stimulus; GO:0051130 (0.05) ! positive regulation of cellular component organization; GO:0048812 (0.05) ! neuron projection morphogenesis; GO:0048585 (0.05) ! negative regulation of response to stimulus; GO:0045892 (0.05) ! negative regulation of transcription, DNA-templated; GO:0045595 (0.05) ! regulation of cell differentiation; GO:0045087 (0.05) ! innate immune response; GO:0044702 (0.05) ! single organism reproductive process; GO:0044087 (0.05) ! regulation of cellular component biogenesis; GO:0042325 (0.05) ! regulation of phosphorylation; GO:0030154 (0.05) ! cell differentiation; GO:0022607 (0.05) ! cellular component assembly; GO:0016192 (0.05) ! vesicle-mediated transport; GO:0010033 (0.05) ! response to organic substance; GO:0009967 (0.05) ! positive regulation of signal transduction; GO:0003008 (0.05) ! system process; GO:1902589 (0.04) ! single-organism organelle organization; GO:0090304 (0.04) ! nucleic acid metabolic process; GO:0080134 (0.04) ! regulation of response to stress; GO:0060828 (0.04) ! regulation of canonical Wnt signaling pathway; GO:0051240 (0.04) ! positive regulation of multicellular organismal process; GO:0051094 (0.04) ! positive regulation of developmental process; GO:0051049 (0.04) ! regulation of transport; GO:0050877 (0.04) ! neurological system process; GO:0048646 (0.04) ! anatomical structure formation involved in morphogenesis; GO:0048589 (0.04) ! developmental growth; GO:0048513 (0.04) ! animal organ development; GO:0045893 (0.04) ! positive regulation of transcription, DNA-templated; GO:0044708 (0.04) ! single-organism behavior; GO:0044093 (0.04) ! positive regulation of molecular function; GO:0042981 (0.04) ! regulation of apoptotic process; GO:0042592 (0.04) ! homeostatic process; GO:0042391 (0.04) ! regulation of membrane potential; GO:0033043 (0.04) ! regulation of organelle organization; GO:0032270 (0.04) ! positive regulation of cellular protein metabolic process; GO:0016567 (0.04) ! protein ubiquitination; GO:0009968 (0.04) ! negative regulation of signal transduction; GO:0009888 (0.04) ! tissue development; GO:0009605 (0.04) ! response to external stimulus; GO:0007010 (0.04) ! cytoskeleton organization; GO:0001932 (0.04) ! regulation of protein phosphorylation; GO:1902533 (0.03) ! positive regulation of intracellular signal transduction; GO:0097190 (0.03) ! apoptotic signaling pathway; GO:0080135 (0.03) ! regulation of cellular response to stress; GO:0051962 (0.03) ! positive regulation of nervous system development; GO:0051338 (0.03) ! regulation of transferase activity; GO:0051336 (0.03) ! regulation of hydrolase activity; GO:0051270 (0.03) ! regulation of cellular component movement; GO:0048675 (0.03) ! axon extension; GO:0048598 (0.03) ! embryonic morphogenesis; GO:0045944 (0.03) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045937 (0.03) ! positive regulation of phosphate metabolic process; GO:0045664 (0.03) ! regulation of neuron differentiation; GO:0044089 (0.03) ! positive regulation of cellular component biogenesis; GO:0043408 (0.03) ! regulation of MAPK cascade; GO:0043085 (0.03) ! positive regulation of catalytic activity; GO:0042127 (0.03) ! regulation of cell proliferation; GO:0040011 (0.03) ! locomotion; GO:0040008 (0.03) ! regulation of growth; GO:0032970 (0.03) ! regulation of actin filament-based process; GO:0031401 (0.03) ! positive regulation of protein modification process; GO:0022603 (0.03) ! regulation of anatomical structure morphogenesis; GO:0022402 (0.03) ! cell cycle process; GO:0019725 (0.03) ! cellular homeostasis; GO:0016070 (0.03) ! RNA metabolic process; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0007613 (0.03) ! memory; GO:0007605 (0.03) ! sensory perception of sound; GO:0007276 (0.03) ! gamete generation; GO:0007275 (0.03) ! multicellular organism development; GO:0007219 (0.03) ! Notch signaling pathway; GO:0006928 (0.03) ! movement of cell or subcellular component; GO:0006897 (0.03) ! endocytosis; GO:0006259 (0.03) ! DNA metabolic process; GO:0002009 (0.03) ! morphogenesis of an epithelium; GO:0000122 (0.03) ! negative regulation of transcription from RNA polymerase II promoter; GO:1903827 (0.02) ! regulation of cellular protein localization; GO:1903779 (0.02) ! regulation of cardiac conduction; GO:1901700 (0.02) ! response to oxygen-containing compound; GO:1900074 (0.02) ! negative regulation of neuromuscular synaptic transmission; GO:0098901 (0.02) ! regulation of cardiac muscle cell action potential; GO:0097193 (0.02) ! intrinsic apoptotic signaling pathway; GO:0090090 (0.02) ! negative regulation of canonical Wnt signaling pathway; GO:0071709 (0.02) ! membrane assembly; GO:0070887 (0.02) ! cellular response to chemical stimulus; GO:0070050 (0.02) ! neuron cellular homeostasis; GO:0060429 (0.02) ! epithelium development; GO:0055117 (0.02) ! regulation of cardiac muscle contraction; GO:0051726 (0.02) ! regulation of cell cycle; GO:0051704 (0.02) ! multi-organism process; GO:0051493 (0.02) ! regulation of cytoskeleton organization; GO:0051345 (0.02) ! positive regulation of hydrolase activity; GO:0051241 (0.02) ! negative regulation of multicellular organismal process; GO:0051223 (0.02) ! regulation of protein transport; GO:0051093 (0.02) ! negative regulation of developmental process; GO:0051050 (0.02) ! positive regulation of transport; GO:0048878 (0.02) ! chemical homeostasis; GO:0048731 (0.02) ! system development; GO:0048468 (0.02) ! cell development; GO:0046330 (0.02) ! positive regulation of JNK cascade; GO:0045887 (0.02) ! positive regulation of synaptic growth at neuromuscular junction; GO:0045859 (0.02) ! regulation of protein kinase activity; GO:0045597 (0.02) ! positive regulation of cell differentiation; GO:0045596 (0.02) ! negative regulation of cell differentiation; GO:0044710 (0.02) ! single-organism metabolic process; GO:0044092 (0.02) ! negative regulation of molecular function; GO:0043933 (0.02) ! macromolecular complex subunit organization; GO:0043207 (0.02) ! response to external biotic stimulus; GO:0043087 (0.02) ! regulation of GTPase activity; GO:0043066 (0.02) ! negative regulation of apoptotic process; GO:0043046 (0.02) ! DNA methylation involved in gamete generation; GO:0042787 (0.02) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0042692 (0.02) ! muscle cell differentiation; GO:0038061 (0.02) ! NIK/NF-kappaB signaling; GO:0035239 (0.02) ! tube morphogenesis; GO:0034587 (0.02) ! piRNA metabolic process; GO:0034097 (0.02) ! response to cytokine; GO:0033554 (0.02) ! cellular response to stress; GO:0032386 (0.02) ! regulation of intracellular transport; GO:0031344 (0.02) ! regulation of cell projection organization; GO:0030155 (0.02) ! regulation of cell adhesion; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0019233 (0.02) ! sensory perception of pain; GO:0016477 (0.02) ! cell migration; GO:0016197 (0.02) ! endosomal transport; GO:0010639 (0.02) ! negative regulation of organelle organization; GO:0009887 (0.02) ! organ morphogenesis; GO:0009886 (0.02) ! post-embryonic morphogenesis; GO:0009790 (0.02) ! embryo development; GO:0007614 (0.02) ! short-term memory; GO:0007528 (0.02) ! neuromuscular junction development; GO:0007389 (0.02) ! pattern specification process; GO:0007283 (0.02) ! spermatogenesis; GO:0007249 (0.02) ! I-kappaB kinase/NF-kappaB signaling; GO:0007140 (0.02) ! male meiosis; GO:0006954 (0.02) ! inflammatory response; GO:0006811 (0.02) ! ion transport; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0002682 (0.02) ! regulation of immune system process; GO:0000226 (0.02) ! microtubule cytoskeleton organization; GO:2001257 (0.01) ! regulation of cation channel activity; GO:2001252 (0.01) ! positive regulation of chromosome organization; GO:2001251 (0.01) ! negative regulation of chromosome organization; GO:2001233 (0.01) ! regulation of apoptotic signaling pathway; GO:2001020 (0.01) ! regulation of response to DNA damage stimulus; GO:2000045 (0.01) ! regulation of G1/S transition of mitotic cell cycle; GO:1990126 (0.01) ! retrograde transport, endosome to plasma membrane; GO:1904059 (0.01) ! regulation of locomotor rhythm; GO:1903707 (0.01) ! negative regulation of hemopoiesis; GO:1903530 (0.01) ! regulation of secretion by cell; GO:1903047 (0.01) ! mitotic cell cycle process; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1901988 (0.01) ! negative regulation of cell cycle phase transition; GO:1901796 (0.01) ! regulation of signal transduction by p53 class mediator; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:1900449 (0.01) ! regulation of glutamate receptor signaling pathway; GO:1900006 (0.01) ! positive regulation of dendrite development; GO:0099601 (0.01) ! regulation of neurotransmitter receptor activity; GO:0098910 (0.01) ! regulation of atrial cardiac muscle cell action potential; GO:0097305 (0.01) ! response to alcohol; GO:0090316 (0.01) ! positive regulation of intracellular protein transport; GO:0090263 (0.01) ! positive regulation of canonical Wnt signaling pathway; GO:0072507 (0.01) ! divalent inorganic cation homeostasis; GO:0071900 (0.01) ! regulation of protein serine/threonine kinase activity; GO:0071495 (0.01) ! cellular response to endogenous stimulus; GO:0071407 (0.01) ! cellular response to organic cyclic compound; GO:0071363 (0.01) ! cellular response to growth factor stimulus; GO:0071345 (0.01) ! cellular response to cytokine stimulus; GO:0071260 (0.01) ! cellular response to mechanical stimulus; GO:0070936 (0.01) ! protein K48-linked ubiquitination; GO:0070925 (0.01) ! organelle assembly; GO:0070542 (0.01) ! response to fatty acid; GO:0061327 (0.01) ! anterior Malpighian tubule development; GO:0061025 (0.01) ! membrane fusion; GO:0060997 (0.01) ! dendritic spine morphogenesis; GO:0060491 (0.01) ! regulation of cell projection assembly; GO:0060271 (0.01) ! cilium morphogenesis; GO:0055065 (0.01) ! metal ion homeostasis; GO:0051865 (0.01) ! protein autoubiquitination; GO:0051597 (0.01) ! response to methylmercury; GO:0051570 (0.01) ! regulation of histone H3-K9 methylation; GO:0051492 (0.01) ! regulation of stress fiber assembly; GO:0051438 (0.01) ! regulation of ubiquitin-protein transferase activity; GO:0051092 (0.01) ! positive regulation of NF-kappaB transcription factor activity; GO:0051054 (0.01) ! positive regulation of DNA metabolic process; GO:0051053 (0.01) ! negative regulation of DNA metabolic process; GO:0051017 (0.01) ! actin filament bundle assembly; GO:0050974 (0.01) ! detection of mechanical stimulus involved in sensory perception; GO:0050960 (0.01) ! detection of temperature stimulus involved in thermoception; GO:0050905 (0.01) ! neuromuscular process; GO:0050776 (0.01) ! regulation of immune response; GO:0050688 (0.01) ! regulation of defense response to virus; GO:0050673 (0.01) ! epithelial cell proliferation; GO:0048534 (0.01) ! hematopoietic or lymphoid organ development; GO:0048514 (0.01) ! blood vessel morphogenesis; GO:0048477 (0.01) ! oogenesis; GO:0048013 (0.01) ! ephrin receptor signaling pathway; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046578 (0.01) ! regulation of Ras protein signal transduction; GO:0046434 (0.01) ! organophosphate catabolic process; GO:0045930 (0.01) ! negative regulation of mitotic cell cycle; GO:0045860 (0.01) ! positive regulation of protein kinase activity; GO:0045787 (0.01) ! positive regulation of cell cycle; GO:0045765 (0.01) ! regulation of angiogenesis; GO:0045747 (0.01) ! positive regulation of Notch signaling pathway; GO:0045665 (0.01) ! negative regulation of neuron differentiation; GO:0045324 (0.01) ! late endosome to vacuole transport; GO:0045314 (0.01) ! regulation of compound eye photoreceptor development; GO:0045214 (0.01) ! sarcomere organization; GO:0045022 (0.01) ! early endosome to late endosome transport; GO:0044030 (0.01) ! regulation of DNA methylation; GO:0043547 (0.01) ! positive regulation of GTPase activity; GO:0043392 (0.01) ! negative regulation of DNA binding; GO:0043123 (0.01) ! positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043086 (0.01) ! negative regulation of catalytic activity; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0042994 (0.01) ! cytoplasmic sequestering of transcription factor; GO:0042742 (0.01) ! defense response to bacterium; GO:0042345 (0.01) ! regulation of NF-kappaB import into nucleus; GO:0042330 (0.01) ! taxis; GO:0042246 (0.01) ! tissue regeneration; GO:0042176 (0.01) ! regulation of protein catabolic process; GO:0038180 (0.01) ! nerve growth factor signaling pathway; GO:0035904 (0.01) ! aorta development; GO:0035690 (0.01) ! cellular response to drug; GO:0035317 (0.01) ! imaginal disc-derived wing hair organization; GO:0035304 (0.01) ! regulation of protein dephosphorylation; GO:0035107 (0.01) ! appendage morphogenesis; GO:0034645 (0.01) ! cellular macromolecule biosynthetic process; GO:0034502 (0.01) ! protein localization to chromosome; GO:0034220 (0.01) ! ion transmembrane transport; GO:0032846 (0.01) ! positive regulation of homeostatic process; GO:0032774 (0.01) ! RNA biosynthetic process; GO:0032496 (0.01) ! response to lipopolysaccharide; GO:0032414 (0.01) ! positive regulation of ion transmembrane transporter activity; GO:0032232 (0.01) ! negative regulation of actin filament bundle assembly; GO:0032102 (0.01) ! negative regulation of response to external stimulus; GO:0031667 (0.01) ! response to nutrient levels; GO:0031589 (0.01) ! cell-substrate adhesion; GO:0031349 (0.01) ! positive regulation of defense response; GO:0031333 (0.01) ! negative regulation of protein complex assembly; GO:0030913 (0.01) ! paranodal junction assembly; GO:0030833 (0.01) ! regulation of actin filament polymerization; GO:0030725 (0.01) ! germline ring canal formation; GO:0030336 (0.01) ! negative regulation of cell migration; GO:0030307 (0.01) ! positive regulation of cell growth; GO:0030162 (0.01) ! regulation of proteolysis; GO:0030100 (0.01) ! regulation of endocytosis; GO:0022407 (0.01) ! regulation of cell-cell adhesion; GO:0021700 (0.01) ! developmental maturation; GO:0021654 (0.01) ! rhombomere boundary formation; GO:0021514 (0.01) ! ventral spinal cord interneuron differentiation; GO:0019827 (0.01) ! stem cell population maintenance; GO:0018345 (0.01) ! protein palmitoylation; GO:0018108 (0.01) ! peptidyl-tyrosine phosphorylation; GO:0018022 (0.01) ! peptidyl-lysine methylation; GO:0016571 (0.01) ! histone methylation; GO:0012501 (0.01) ! programmed cell death; GO:0010959 (0.01) ! regulation of metal ion transport; GO:0010921 (0.01) ! regulation of phosphatase activity; GO:0010810 (0.01) ! regulation of cell-substrate adhesion; GO:0010769 (0.01) ! regulation of cell morphogenesis involved in differentiation; GO:0010243 (0.01) ! response to organonitrogen compound; GO:0010035 (0.01) ! response to inorganic substance; GO:0010001 (0.01) ! glial cell differentiation; GO:0009953 (0.01) ! dorsal/ventral pattern formation; GO:0009913 (0.01) ! epidermal cell differentiation; GO:0009791 (0.01) ! post-embryonic development; GO:0009788 (0.01) ! negative regulation of abscisic acid-activated signaling pathway; GO:0009725 (0.01) ! response to hormone; GO:0009636 (0.01) ! response to toxic substance; GO:0009615 (0.01) ! response to virus; GO:0009593 (0.01) ! detection of chemical stimulus; GO:0009416 (0.01) ! response to light stimulus; GO:0008544 (0.01) ! epidermis development; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0007638 (0.01) ! mechanosensory behavior; GO:0007626 (0.01) ! locomotory behavior; GO:0007616 (0.01) ! long-term memory; GO:0007612 (0.01) ! learning; GO:0007560 (0.01) ! imaginal disc morphogenesis; GO:0007520 (0.01) ! myoblast fusion; GO:0007507 (0.01) ! heart development; GO:0007423 (0.01) ! sensory organ development; GO:0007411 (0.01) ! axon guidance; GO:0007409 (0.01) ! axonogenesis; GO:0007399 (0.01) ! nervous system development; GO:0007391 (0.01) ! dorsal closure; GO:0007298 (0.01) ! border follicle cell migration; GO:0007221 (0.01) ! positive regulation of transcription of Notch receptor target; GO:0007163 (0.01) ! establishment or maintenance of cell polarity; GO:0007162 (0.01) ! negative regulation of cell adhesion; GO:0007154 (0.01) ! cell communication; GO:0007030 (0.01) ! Golgi organization; GO:0006974 (0.01) ! cellular response to DNA damage stimulus; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006873 (0.01) ! cellular ion homeostasis; GO:0006816 (0.01) ! calcium ion transport; GO:0006650 (0.01) ! glycerophospholipid metabolic process; GO:0006543 (0.01) ! glutamine catabolic process; GO:0006537 (0.01) ! glutamate biosynthetic process; GO:0006508 (0.01) ! proteolysis; GO:0006471 (0.01) ! protein ADP-ribosylation; GO:0006461 (0.01) ! protein complex assembly; GO:0006417 (0.01) ! regulation of translation; GO:0003013 (0.01) ! circulatory system process; GO:0002684 (0.01) ! positive regulation of immune system process; GO:0002252 (0.01) ! immune effector process; GO:0002244 (0.01) ! hematopoietic progenitor cell differentiation; GO:0001946 (0.01) ! lymphangiogenesis; GO:0001938 (0.01) ! positive regulation of endothelial cell proliferation; GO:0001933 (0.01) ! negative regulation of protein phosphorylation; GO:0001889 (0.01) ! liver development; GO:0001817 (0.01) ! regulation of cytokine production; GO:0001701 (0.01) ! in utero embryonic development; GO:0001569 (0.01) ! patterning of blood vessels; GO:0001525 (0.01) ! angiogenesis; GO:0000904 (0.01) ! cell morphogenesis involved in differentiation GO:0044464 (0.92) ! cell part; GO:0044424 (0.84) ! intracellular part; GO:0005737 (0.60) ! cytoplasm; GO:0043226 (0.46) ! organelle; GO:0043229 (0.45) ! intracellular organelle; GO:0043231 (0.41) ! intracellular membrane-bounded organelle; GO:0005634 (0.36) ! nucleus; GO:0032991 (0.26) ! macromolecular complex; GO:0043234 (0.24) ! protein complex; GO:1902494 (0.19) ! catalytic complex; GO:0044444 (0.19) ! cytoplasmic part; GO:0016020 (0.18) ! membrane; GO:0000151 (0.18) ! ubiquitin ligase complex; GO:0044422 (0.16) ! organelle part; GO:0044446 (0.12) ! intracellular organelle part; GO:0044425 (0.09) ! membrane part; GO:0005886 (0.09) ! plasma membrane; GO:0044459 (0.07) ! plasma membrane part; GO:0097458 (0.06) ! neuron part; GO:0044428 (0.06) ! nuclear part; GO:0043232 (0.06) ! intracellular non-membrane-bounded organelle; GO:0044449 (0.05) ! contractile fiber part; GO:0042995 (0.05) ! cell projection; GO:0005829 (0.05) ! cytosol; GO:0043005 (0.04) ! neuron projection; GO:0030054 (0.04) ! cell junction; GO:0005887 (0.04) ! integral component of plasma membrane; GO:0005654 (0.04) ! nucleoplasm; GO:0098590 (0.03) ! plasma membrane region; GO:0044463 (0.03) ! cell projection part; GO:0044456 (0.03) ! synapse part; GO:0031982 (0.03) ! vesicle; GO:0005912 (0.03) ! adherens junction; GO:0005773 (0.03) ! vacuole; GO:0098588 (0.02) ! bounding membrane of organelle; GO:0097060 (0.02) ! synaptic membrane; GO:0071546 (0.02) ! pi-body; GO:0044431 (0.02) ! Golgi apparatus part; GO:0044430 (0.02) ! cytoskeletal part; GO:0044427 (0.02) ! chromosomal part; GO:0043034 (0.02) ! costamere; GO:0033267 (0.02) ! axon part; GO:0033256 (0.02) ! I-kappaB/NF-kappaB complex; GO:0031988 (0.02) ! membrane-bounded vesicle; GO:0031594 (0.02) ! neuromuscular junction; GO:0031410 (0.02) ! cytoplasmic vesicle; GO:0030018 (0.02) ! Z disc; GO:0005911 (0.02) ! cell-cell junction; GO:0005856 (0.02) ! cytoskeleton; GO:0005769 (0.02) ! early endosome; GO:0097422 (0.01) ! tubular endosome; GO:0070062 (0.01) ! extracellular exosome; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0045211 (0.01) ! postsynaptic membrane; GO:0045179 (0.01) ! apical cortex; GO:0045177 (0.01) ! apical part of cell; GO:0045121 (0.01) ! membrane raft; GO:0044454 (0.01) ! nuclear chromosome part; GO:0043296 (0.01) ! apical junction complex; GO:0043235 (0.01) ! receptor complex; GO:0043195 (0.01) ! terminal bouton; GO:0043025 (0.01) ! neuronal cell body; GO:0042734 (0.01) ! presynaptic membrane; GO:0042383 (0.01) ! sarcolemma; GO:0036062 (0.01) ! presynaptic periactive zone; GO:0034703 (0.01) ! cation channel complex; GO:0031941 (0.01) ! filamentous actin; GO:0031672 (0.01) ! A band; GO:0031253 (0.01) ! cell projection membrane; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030133 (0.01) ! transport vesicle; GO:0030017 (0.01) ! sarcomere; GO:0016328 (0.01) ! lateral plasma membrane; GO:0015629 (0.01) ! actin cytoskeleton; GO:0014069 (0.01) ! postsynaptic density; GO:0009986 (0.01) ! cell surface; GO:0005929 (0.01) ! cilium; GO:0005925 (0.01) ! focal adhesion; GO:0005813 (0.01) ! centrosome; GO:0005802 (0.01) ! trans-Golgi network; GO:0005794 (0.01) ! Golgi apparatus; GO:0005783 (0.01) ! endoplasmic reticulum; GO:0005774 (0.01) ! vacuolar membrane; GO:0005770 (0.01) ! late endosome; GO:0005759 (0.01) ! mitochondrial matrix; GO:0005739 (0.01) ! mitochondrion; GO:0005622 (0.01) ! intracellular; GO:0005615 (0.01) ! extracellular space; GO:0000785 (0.01) ! chromatin; GO:0000139 (0.01) ! Golgi membrane GO:0016020 ! membrane; GO:0005737 ! cytoplasm 3 75500261-75515583 (17q25.1) High: stomach 2 (glandular cells);stomach 1 (glandular cells);cerebral cortex (endothelial cells);kidney (cells in glomeruli);Medium: colon (endothelial cells; glandular cells; peripheral nerve/ganglion);gallbladder (glandular cells);kidney (cells in tubules);testis (cells in seminiferous ducts; Leydig cells);caudate (glial cells);thyroid gland (glandular cells);epididymis (glandular cells);adrenal gland (glandular cells);endometrium 1 (glandular cells);endometrium 2 (glandular cells);salivary gland (glandular cells);duodenum (glandular cells);cerebral cortex (neuronal cells);placenta (trophoblastic cells);hippocampus (neuronal cells);bronchus (respiratory epithelial cells);appendix (glandular cells);heart muscle (myocytes);rectum (glandular cells);cervix, uterine (squamous epithelial cells);pancreas (exocrine glandular cells);cerebellum (cells in granular layer; cells in molecular layer; Purkinje cells);fallopian tube (glandular cells);soft tissue 1 (fibroblasts);soft tissue 2 (fibroblasts);small intestine (glandular cells);nasopharynx (respiratory epithelial cells);lung (pneumocytes);ovary (follicle cells);Low: lymph node (germinal center cells; non-germinal center cells);prostate (glandular cells);caudate (neuronal cells);spleen (cells in white pulp);bone marrow (hematopoietic cells);soft tissue 2 (peripheral nerve);tonsil (germinal center cells; non-germinal center cells; squamous epithelial cells);parathyroid gland (glandular cells);vagina (squamous epithelial cells);appendix (lymphoid tissue);skin 1 (keratinocytes);soft tissue 1 (peripheral nerve);esophagus (squamous epithelial cells);skin 2 (epidermal cells);cerebral cortex (neuropil);ovary (ovarian stroma cells);cervix, uterine (glandular cells);pancreas (islets of Langerhans); Nerve - Tibial: 140.95; Lung: 78.05; Fallopian Tube: 61.11; Spleen: 55.80; Adipose - Visceral (Omentum): 50.51; Thyroid: 50.23; Breast - Mammary Tissue: 49.02; Uterus: 48.01; Adipose - Subcutaneous: 46.88; Artery - Coronary: 37.66; Cervix - Ectocervix: 36.87; Esophagus - Muscularis: 36.52; Cervix - Endocervix: 36.51; Esophagus - Gastroesophageal Junction: 35.62; Artery - Aorta: 33.79; Artery - Tibial: 32.97; Bladder: 32.05; Colon - Sigmoid: 30.59; Prostate: 30.14; Kidney - Cortex: 28.82; Adrenal Gland: 27.68; Vagina: 26.42; Pituitary: 26.06; Brain - Cerebellum: 25.31; Ovary: 24.10; Brain - Spinal cord (cervical c-1): 22.36; Skin - Sun Exposed (Lower leg): 21.50; Skin - Not Sun Exposed (Suprapubic): 19.77; Brain - Cerebellar Hemisphere: 19.59; Stomach: 19.05; Brain - Cortex: 18.64; Colon - Transverse: 18.52; Minor Salivary Gland: 18.49; Brain - Caudate (basal ganglia): 17.23; Heart - Atrial Appendage: 16.70; Brain - Amygdala: 16.41; Brain - Nucleus accumbens (basal ganglia): 16.08; Brain - Substantia nigra: 15.97; Brain - Putamen (basal ganglia): 15.55; Heart - Left Ventricle: 15.23; Small Intestine - Terminal Ileum: 15.22; Esophagus - Mucosa: 15.10; Brain - Hypothalamus: 14.57; Testis: 13.60; Brain - Frontal Cortex (BA9): 13.49; Brain - Anterior cingulate cortex (BA24): 13.34; Brain - Hippocampus: 13.29; Muscle - Skeletal: 11.33; Cells - Transformed fibroblasts: 7.78; Liver: 7.74; Pancreas: 7.32; Cells - EBV-transformed lymphocytes: 0.38; Whole Blood: 0.24; MGREQDLILAVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDFWNLHDPTALNVRAGDVITVLEQHPDGRWKGHIHESQRGTDRIGYFPPGIVEVVSKRVGIPAARLPSAPTPLRPGFSRTPQPPAEEPPHPLTYSQLPRVGLSPDSPAGDRNSVGSEGSVGSIRSAGSGQSSEGTNGHGPGLLIENAQPLPSAGEDQVLPGLHPPSLADNLSHRPLANCRSGEQIFTQDVRPEQLLEGKDAQAIHNWLSEFQLEGYTAHFLQAGYDVPTISRMTPEDLTAIGVTKPGHRKKIASEIAQLSIAEWLPSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEELQEIGVNKLGHQKKLMLGVKRLAELRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQEGTPSASTKHILDDISTMFDALADQLDAMLD SMIM5 Small integral membrane protein 5 SMIM5_HUMAN (Q71RC9-1) GO:0051015 (0.33) ! actin filament binding; GO:0030274 (0.33) ! LIM domain binding; GO:0017166 (0.33) ! vinculin binding; GO:0005200 (0.33) ! structural constituent of cytoskeleton; GO:0005178 (0.33) ! integrin binding GO:0098876 (0.48) ! vesicle-mediated transport to the plasma membrane; GO:0071702 (0.48) ! organic substance transport; GO:0051278 (0.48) ! fungal-type cell wall polysaccharide biosynthetic process; GO:0045184 (0.48) ! establishment of protein localization; GO:0030010 (0.48) ! establishment of cell polarity; GO:0006892 (0.48) ! post-Golgi vesicle-mediated transport; GO:0006038 (0.48) ! cell wall chitin biosynthetic process; GO:0000281 (0.48) ! mitotic cytokinesis; GO:0070527 (0.33) ! platelet aggregation; GO:0030866 (0.33) ! cortical actin cytoskeleton organization; GO:0007044 (0.33) ! cell-substrate junction assembly; GO:0007016 (0.33) ! cytoskeletal anchoring at plasma membrane GO:0044424 (1.00) ! intracellular part; GO:0044446 (0.93) ! intracellular organelle part; GO:0043229 (0.93) ! intracellular organelle; GO:0043227 (0.93) ! membrane-bounded organelle; GO:0016020 (0.93) ! membrane; GO:0044444 (0.60) ! cytoplasmic part; GO:0043234 (0.60) ! protein complex; GO:0044431 (0.53) ! Golgi apparatus part; GO:0044425 (0.53) ! membrane part; GO:0005794 (0.53) ! Golgi apparatus; GO:0031988 (0.47) ! membrane-bounded vesicle; GO:0005737 (0.47) ! cytoplasm; GO:0070062 (0.40) ! extracellular exosome; GO:0044430 (0.40) ! cytoskeletal part; GO:0034044 (0.40) ! exomer complex; GO:0005925 (0.40) ! focal adhesion; GO:0005886 (0.40) ! plasma membrane; GO:0005856 (0.40) ! cytoskeleton; GO:0032587 (0.33) ! ruffle membrane; GO:0009986 (0.33) ! cell surface; GO:0005815 (0.33) ! microtubule organizing center; GO:0001726 (0.33) ! ruffle; GO:0031090 (0.20) ! organelle membrane; GO:0043529 (0.13) ! GET complex; GO:0022627 (0.13) ! cytosolic small ribosomal subunit; GO:0016021 (0.13) ! integral component of membrane; GO:0005789 (0.13) ! endoplasmic reticulum membrane; GO:0005783 (0.13) ! endoplasmic reticulum; GO:0000139 (0.13) ! Golgi membrane; GO:1990357 (0.07) ! terminal web; GO:0098723 (0.07) ! skeletal muscle myofibril; GO:0090637 (0.07) ! inner dense plaque of desmosome; GO:0090636 (0.07) ! outer dense plaque of desmosome; GO:0045121 (0.07) ! membrane raft; GO:0043034 (0.07) ! costamere; GO:0042383 (0.07) ! sarcolemma; GO:0031594 (0.07) ! neuromuscular junction; GO:0030486 (0.07) ! smooth muscle dense body; GO:0030140 (0.07) ! trans-Golgi network transport vesicle; GO:0030018 (0.07) ! Z disc; GO:0015629 (0.07) ! actin cytoskeleton; GO:0005927 (0.07) ! muscle tendon junction; GO:0005916 (0.07) ! fascia adherens; GO:0005915 (0.07) ! zonula adherens; GO:0005903 (0.07) ! brush border; GO:0005743 (0.07) ! mitochondrial inner membrane; GO:0005623 (0.07) ! cell; GO:0001725 (0.07) ! stress fiber GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 2 75633434-75641404 (17q25.1) High: stomach 2 (glandular cells);stomach 1 (glandular cells);seminal vesicle (glandular cells);colon (endothelial cells; glandular cells);gallbladder (glandular cells);esophagus (squamous epithelial cells);kidney (cells in glomeruli; cells in tubules);testis (cells in seminiferous ducts; Leydig cells);caudate (glial cells; neuronal cells);tonsil (germinal center cells; non-germinal center cells; squamous epithelial cells);thyroid gland (glandular cells);epididymis (glandular cells);adrenal gland (glandular cells);endometrium 1 (cells in endometrial stroma; glandular cells);endometrium 2 (cells in endometrial stroma; glandular cells);salivary gland (glandular cells);smooth muscle (smooth muscle cells);pancreas (exocrine glandular cells; islets of Langerhans);cerebral cortex (endothelial cells; glial cells; neuronal cells);vagina (squamous epithelial cells);lymph node (germinal center cells; non-germinal center cells);placenta (decidual cells; trophoblastic cells);hippocampus (glial cells; neuronal cells);bronchus (respiratory epithelial cells);parathyroid gland (glandular cells);skeletal muscle (myocytes);urinary bladder (urothelial cells);appendix (glandular cells; lymphoid tissue);breast (glandular cells; myoepithelial cells);rectum (glandular cells);prostate (glandular cells);cervix, uterine (glandular cells; squamous epithelial cells);duodenum (glandular cells);cerebellum (cells in granular layer; cells in molecular layer; Purkinje cells);fallopian tube (glandular cells);spleen (cells in red pulp; cells in white pulp);bone marrow (hematopoietic cells);soft tissue 2 (adipocytes; peripheral nerve);skin 2 (epidermal cells);small intestine (glandular cells);soft tissue 1 (adipocytes; chondrocytes);nasopharynx (respiratory epithelial cells);lung (macrophages; pneumocytes);ovary (ovarian stroma cells);oral mucosa (squamous epithelial cells);skin 1 (keratinocytes; melanocytes);heart muscle (myocytes);Medium: soft tissue 1 (fibroblasts);soft tissue 2 (fibroblasts);skin 1 (fibroblasts);breast (adipocytes);liver (bile duct cells; hepatocytes); Nerve - Tibial: 22.75; Thyroid: 19.07; Esophagus - Mucosa: 17.48; Kidney - Cortex: 13.62; Vagina: 11.37; Brain - Spinal cord (cervical c-1): 10.94; Skin - Not Sun Exposed (Suprapubic): 10.23; Bladder: 9.60; Small Intestine - Terminal Ileum: 9.44; Skin - Sun Exposed (Lower leg): 9.41; Colon - Transverse: 6.65; Cervix - Endocervix: 5.65; Stomach: 5.16; Fallopian Tube: 4.81; Colon - Sigmoid: 4.11; Spleen: 4.00; Prostate: 3.37; Heart - Atrial Appendage: 3.31; Heart - Left Ventricle: 3.20; Cervix - Ectocervix: 3.15; Testis: 3.14; Minor Salivary Gland: 3.06; Esophagus - Gastroesophageal Junction: 2.90; Whole Blood: 2.84; Lung: 2.80; Brain - Substantia nigra: 2.79; Esophagus - Muscularis: 2.67; Brain - Hippocampus: 2.29; Ovary: 2.23; Pituitary: 2.05; Brain - Hypothalamus: 1.85; Uterus: 1.72; Brain - Cerebellum: 1.22; Artery - Coronary: 1.16; Breast - Mammary Tissue: 1.13; Brain - Cerebellar Hemisphere: 1.05; Brain - Amygdala: 1.02; Brain - Caudate (basal ganglia): 1.00; Brain - Putamen (basal ganglia): 0.93; Adipose - Subcutaneous: 0.92; Adipose - Visceral (Omentum): 0.91; Pancreas: 0.88; Brain - Cortex: 0.81; Brain - Frontal Cortex (BA9): 0.66; Brain - Nucleus accumbens (basal ganglia): 0.62; Brain - Anterior cingulate cortex (BA24): 0.52; Artery - Tibial: 0.52; Artery - Aorta: 0.48; Adrenal Gland: 0.40; Liver: 0.40; Cells - EBV-transformed lymphocytes: 0.38; Cells - Transformed fibroblasts: 0.19; Muscle - Skeletal: 0.18; MAATDFVQEMRAVGERLLLKLQRLPQAEPVEIVAFSVIILFTATVLLLLLIACSCCCTHCCCPERRGRKVQVQPTPP TRIM47 Tripartite motif-containing protein 47 TRI47_HUMAN (Q96LD4-1) GO:0003824 (0.79) ! catalytic activity; GO:0004842 (0.76) ! ubiquitin-protein transferase activity; GO:0061630 (0.31) ! ubiquitin protein ligase activity; GO:0046872 (0.21) ! metal ion binding; GO:0004871 (0.21) ! signal transducer activity; GO:0004872 (0.20) ! receptor activity; GO:0008329 (0.19) ! signaling pattern recognition receptor activity; GO:0008270 (0.19) ! zinc ion binding; GO:0042802 (0.16) ! identical protein binding; GO:0019899 (0.14) ! enzyme binding; GO:0016787 (0.14) ! hydrolase activity; GO:0042803 (0.12) ! protein homodimerization activity; GO:0005102 (0.12) ! receptor binding; GO:0050827 (0.11) ! toxin receptor binding; GO:0004222 (0.11) ! metalloendopeptidase activity; GO:0030674 (0.09) ! protein binding, bridging; GO:0019901 (0.09) ! protein kinase binding; GO:1901982 (0.06) ! maltose binding; GO:0016874 (0.06) ! ligase activity; GO:0008320 (0.06) ! protein transmembrane transporter activity; GO:0005363 (0.06) ! maltose transmembrane transporter activity; GO:0003676 (0.06) ! nucleic acid binding; GO:0044877 (0.05) ! macromolecular complex binding; GO:0032182 (0.04) ! ubiquitin-like protein binding; GO:0019904 (0.04) ! protein domain specific binding; GO:0008092 (0.04) ! cytoskeletal protein binding; GO:0003682 (0.04) ! chromatin binding; GO:0003677 (0.04) ! DNA binding; GO:0042393 (0.03) ! histone binding; GO:0016887 (0.03) ! ATPase activity; GO:0015631 (0.03) ! tubulin binding; GO:0005543 (0.03) ! phospholipid binding; GO:0003723 (0.03) ! RNA binding; GO:0072572 (0.02) ! poly-ADP-D-ribose binding; GO:0051219 (0.02) ! phosphoprotein binding; GO:0046982 (0.02) ! protein heterodimerization activity; GO:0044822 (0.02) ! poly(A) RNA binding; GO:0043142 (0.02) ! single-stranded DNA-dependent ATPase activity; GO:0043130 (0.02) ! ubiquitin binding; GO:0032184 (0.02) ! SUMO polymer binding; GO:0032089 (0.02) ! NACHT domain binding; GO:0031625 (0.02) ! ubiquitin protein ligase binding; GO:0031624 (0.02) ! ubiquitin conjugating enzyme binding; GO:0019966 (0.02) ! interleukin-1 binding; GO:0008017 (0.02) ! microtubule binding; GO:0001786 (0.02) ! phosphatidylserine binding; GO:1990782 (0.01) ! protein tyrosine kinase binding; GO:1904264 (0.01) ! ubiquitin protein ligase activity involved in ERAD pathway; GO:0098641 (0.01) ! cadherin binding involved in cell-cell adhesion; GO:0070530 (0.01) ! K63-linked polyubiquitin binding; GO:0050681 (0.01) ! androgen receptor binding; GO:0044212 (0.01) ! transcription regulatory region DNA binding; GO:0043021 (0.01) ! ribonucleoprotein complex binding; GO:0035035 (0.01) ! histone acetyltransferase binding; GO:0031432 (0.01) ! titin binding; GO:0030234 (0.01) ! enzyme regulator activity; GO:0030165 (0.01) ! PDZ domain binding; GO:0008134 (0.01) ! transcription factor binding; GO:0004714 (0.01) ! transmembrane receptor protein tyrosine kinase activity; GO:0003712 (0.01) ! transcription cofactor activity; GO:0003700 (0.01) ! transcription factor activity, sequence-specific DNA binding GO:0009987 (0.85) ! cellular process; GO:0065007 (0.84) ! biological regulation; GO:0050789 (0.69) ! regulation of biological process; GO:0050794 (0.66) ! regulation of cellular process; GO:0071704 (0.60) ! organic substance metabolic process; GO:0044238 (0.60) ! primary metabolic process; GO:0044260 (0.59) ! cellular macromolecule metabolic process; GO:0031323 (0.54) ! regulation of cellular metabolic process; GO:0019538 (0.54) ! protein metabolic process; GO:0060255 (0.53) ! regulation of macromolecule metabolic process; GO:0080090 (0.52) ! regulation of primary metabolic process; GO:0048518 (0.50) ! positive regulation of biological process; GO:0006464 (0.50) ! cellular protein modification process; GO:0032446 (0.48) ! protein modification by small protein conjugation; GO:0048522 (0.47) ! positive regulation of cellular process; GO:0016567 (0.47) ! protein ubiquitination; GO:0065008 (0.46) ! regulation of biological quality; GO:0044764 (0.46) ! multi-organism cellular process; GO:0051715 (0.43) ! cytolysis in other organism; GO:0010468 (0.41) ! regulation of gene expression; GO:2001141 (0.40) ! regulation of RNA biosynthetic process; GO:2000112 (0.40) ! regulation of cellular macromolecule biosynthetic process; GO:0006355 (0.39) ! regulation of transcription, DNA-templated; GO:0050896 (0.36) ! response to stimulus; GO:0048519 (0.35) ! negative regulation of biological process; GO:0048583 (0.34) ! regulation of response to stimulus; GO:0010604 (0.34) ! positive regulation of macromolecule metabolic process; GO:0051246 (0.33) ! regulation of protein metabolic process; GO:0048523 (0.33) ! negative regulation of cellular process; GO:0031325 (0.33) ! positive regulation of cellular metabolic process; GO:0032268 (0.32) ! regulation of cellular protein metabolic process; GO:0044699 (0.29) ! single-organism process; GO:0006950 (0.29) ! response to stress; GO:0051247 (0.28) ! positive regulation of protein metabolic process; GO:0032270 (0.27) ! positive regulation of cellular protein metabolic process; GO:0009966 (0.27) ! regulation of signal transduction; GO:0002376 (0.27) ! immune system process; GO:0048584 (0.26) ! positive regulation of response to stimulus; GO:0009892 (0.25) ! negative regulation of metabolic process; GO:0065009 (0.24) ! regulation of molecular function; GO:0043900 (0.24) ! regulation of multi-organism process; GO:0031399 (0.24) ! regulation of protein modification process; GO:0031324 (0.24) ! negative regulation of cellular metabolic process; GO:0010605 (0.23) ! negative regulation of macromolecule metabolic process; GO:0000209 (0.23) ! protein polyubiquitination; GO:0051090 (0.22) ! regulation of sequence-specific DNA binding transcription factor activity; GO:0044763 (0.22) ! single-organism cellular process; GO:0009967 (0.22) ! positive regulation of signal transduction; GO:0044093 (0.21) ! positive regulation of molecular function; GO:0016043 (0.21) ! cellular component organization; GO:1902531 (0.20) ! regulation of intracellular signal transduction; GO:0080134 (0.20) ! regulation of response to stress; GO:0051091 (0.20) ! positive regulation of sequence-specific DNA binding transcription factor activity; GO:0032502 (0.19) ! developmental process; GO:0031401 (0.19) ! positive regulation of protein modification process; GO:0031327 (0.19) ! negative regulation of cellular biosynthetic process; GO:0044767 (0.18) ! single-organism developmental process; GO:1902533 (0.17) ! positive regulation of intracellular signal transduction; GO:0051092 (0.17) ! positive regulation of NF-kappaB transcription factor activity; GO:0043122 (0.17) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0009057 (0.17) ! macromolecule catabolic process; GO:0002682 (0.17) ! regulation of immune system process; GO:0070534 (0.16) ! protein K63-linked ubiquitination; GO:0051716 (0.16) ! cellular response to stimulus; GO:0050776 (0.16) ! regulation of immune response; GO:0043123 (0.16) ! positive regulation of I-kappaB kinase/NF-kappaB signaling; GO:0006511 (0.16) ! ubiquitin-dependent protein catabolic process; GO:0006259 (0.16) ! DNA metabolic process; GO:0033554 (0.15) ! cellular response to stress; GO:0031347 (0.15) ! regulation of defense response; GO:0006952 (0.15) ! defense response; GO:0050792 (0.14) ! regulation of viral process; GO:0045088 (0.14) ! regulation of innate immune response; GO:0006974 (0.14) ! cellular response to DNA damage stimulus; GO:0001932 (0.14) ! regulation of protein phosphorylation; GO:1903900 (0.13) ! regulation of viral life cycle; GO:1902679 (0.13) ! negative regulation of RNA biosynthetic process; GO:0048856 (0.13) ! anatomical structure development; GO:0045935 (0.13) ! positive regulation of nucleobase-containing compound metabolic process; GO:0043933 (0.13) ! macromolecular complex subunit organization; GO:0032101 (0.13) ! regulation of response to external stimulus; GO:0030163 (0.13) ! protein catabolic process; GO:0010629 (0.13) ! negative regulation of gene expression; GO:0006955 (0.13) ! immune response; GO:0006357 (0.13) ! regulation of transcription from RNA polymerase II promoter; GO:0006281 (0.13) ! DNA repair; GO:0002831 (0.13) ! regulation of response to biotic stimulus; GO:0002684 (0.13) ! positive regulation of immune system process; GO:0001934 (0.13) ! positive regulation of protein phosphorylation; GO:0051248 (0.12) ! negative regulation of protein metabolic process; GO:0051239 (0.12) ! regulation of multicellular organismal process; GO:0051128 (0.12) ! regulation of cellular component organization; GO:0045089 (0.12) ! positive regulation of innate immune response; GO:0045087 (0.12) ! innate immune response; GO:0043410 (0.12) ! positive regulation of MAPK cascade; GO:0043161 (0.12) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0022607 (0.12) ! cellular component assembly; GO:1903901 (0.11) ! negative regulation of viral life cycle; GO:0033043 (0.11) ! regulation of organelle organization; GO:0032501 (0.11) ! multicellular organismal process; GO:0031664 (0.11) ! regulation of lipopolysaccharide-mediated signaling pathway; GO:0031400 (0.11) ! negative regulation of protein modification process; GO:0002218 (0.11) ! activation of innate immune response; GO:0051726 (0.10) ! regulation of cell cycle; GO:0045893 (0.10) ! positive regulation of transcription, DNA-templated; GO:0032879 (0.10) ! regulation of localization; GO:0030162 (0.10) ! regulation of proteolysis; GO:0010033 (0.10) ! response to organic substance; GO:0006310 (0.10) ! DNA recombination; GO:0006302 (0.10) ! double-strand break repair; GO:0001817 (0.10) ! regulation of cytokine production; GO:1902186 (0.09) ! regulation of viral release from host cell; GO:0051129 (0.09) ! negative regulation of cellular component organization; GO:0042176 (0.09) ! regulation of protein catabolic process; GO:0032880 (0.09) ! regulation of protein localization; GO:0009628 (0.09) ! response to abiotic stimulus; GO:1903050 (0.08) ! regulation of proteolysis involved in cellular protein catabolic process; GO:1902275 (0.08) ! regulation of chromatin organization; GO:1902187 (0.08) ! negative regulation of viral release from host cell; GO:0071822 (0.08) ! protein complex subunit organization; GO:0051865 (0.08) ! protein autoubiquitination; GO:0046596 (0.08) ! regulation of viral entry into host cell; GO:0045862 (0.08) ! positive regulation of proteolysis; GO:0045787 (0.08) ! positive regulation of cell cycle; GO:0045732 (0.08) ! positive regulation of protein catabolic process; GO:0010639 (0.08) ! negative regulation of organelle organization; GO:0006996 (0.08) ! organelle organization; GO:0006513 (0.08) ! protein monoubiquitination; GO:1902589 (0.07) ! single-organism organelle organization; GO:0071158 (0.07) ! positive regulation of cell cycle arrest; GO:0048869 (0.07) ! cellular developmental process; GO:0045944 (0.07) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045892 (0.07) ! negative regulation of transcription, DNA-templated; GO:0045717 (0.07) ! negative regulation of fatty acid biosynthetic process; GO:0044707 (0.07) ! single-multicellular organism process; GO:0042127 (0.07) ! regulation of cell proliferation; GO:0032436 (0.07) ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process; GO:0016570 (0.07) ! histone modification; GO:0010638 (0.07) ! positive regulation of organelle organization; GO:0009314 (0.07) ! response to radiation; GO:0007165 (0.07) ! signal transduction; GO:0000724 (0.07) ! double-strand break repair via homologous recombination; GO:1903530 (0.06) ! regulation of secretion by cell; GO:1901700 (0.06) ! response to oxygen-containing compound; GO:0070925 (0.06) ! organelle assembly; GO:0070201 (0.06) ! regulation of establishment of protein localization; GO:0051259 (0.06) ! protein oligomerization; GO:0051240 (0.06) ! positive regulation of multicellular organismal process; GO:0051179 (0.06) ! localization; GO:0051052 (0.06) ! regulation of DNA metabolic process; GO:0046597 (0.06) ! negative regulation of viral entry into host cell; GO:0035067 (0.06) ! negative regulation of histone acetylation; GO:0035066 (0.06) ! positive regulation of histone acetylation; GO:0032897 (0.06) ! negative regulation of viral transcription; GO:0010927 (0.06) ! cellular component assembly involved in morphogenesis; GO:0009605 (0.06) ! response to external stimulus; GO:0002252 (0.06) ! immune effector process; GO:2000026 (0.05) ! regulation of multicellular organismal development; GO:0080135 (0.05) ! regulation of cellular response to stress; GO:0051641 (0.05) ! cellular localization; GO:0051241 (0.05) ! negative regulation of multicellular organismal process; GO:0050707 (0.05) ! regulation of cytokine secretion; GO:0048585 (0.05) ! negative regulation of response to stimulus; GO:0048513 (0.05) ! animal organ development; GO:0044710 (0.05) ! single-organism metabolic process; GO:0042981 (0.05) ! regulation of apoptotic process; GO:0040029 (0.05) ! regulation of gene expression, epigenetic; GO:0033522 (0.05) ! histone H2A ubiquitination; GO:0010508 (0.05) ! positive regulation of autophagy; GO:0010212 (0.05) ! response to ionizing radiation; GO:0008104 (0.05) ! protein localization; GO:0007275 (0.05) ! multicellular organism development; GO:0007166 (0.05) ! cell surface receptor signaling pathway; GO:0001819 (0.05) ! positive regulation of cytokine production; GO:0000122 (0.05) ! negative regulation of transcription from RNA polymerase II promoter; GO:1903320 (0.04) ! regulation of protein modification by small protein conjugation or removal; GO:0070206 (0.04) ! protein trimerization; GO:0060333 (0.04) ! interferon-gamma-mediated signaling pathway; GO:0045739 (0.04) ! positive regulation of DNA repair; GO:0045595 (0.04) ! regulation of cell differentiation; GO:0043009 (0.04) ! chordate embryonic development; GO:0042787 (0.04) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0042384 (0.04) ! cilium assembly; GO:0034097 (0.04) ! response to cytokine; GO:0033993 (0.04) ! response to lipid; GO:0009968 (0.04) ! negative regulation of signal transduction; GO:0009615 (0.04) ! response to virus; GO:0009048 (0.04) ! dosage compensation by inactivation of X chromosome; GO:0006810 (0.04) ! transport; GO:0006301 (0.04) ! postreplication repair; GO:0003012 (0.04) ! muscle system process; GO:0001818 (0.04) ! negative regulation of cytokine production; GO:1903321 (0.03) ! negative regulation of protein modification by small protein conjugation or removal; GO:0070936 (0.03) ! protein K48-linked ubiquitination; GO:0070535 (0.03) ! histone H2A K63-linked ubiquitination; GO:0051649 (0.03) ! establishment of localization in cell; GO:0051607 (0.03) ! defense response to virus; GO:0051493 (0.03) ! regulation of cytoskeleton organization; GO:0051260 (0.03) ! protein homooligomerization; GO:0051094 (0.03) ! positive regulation of developmental process; GO:0051051 (0.03) ! negative regulation of transport; GO:0050715 (0.03) ! positive regulation of cytokine secretion; GO:0048468 (0.03) ! cell development; GO:0045786 (0.03) ! negative regulation of cell cycle; GO:0045597 (0.03) ! positive regulation of cell differentiation; GO:0045190 (0.03) ! isotype switching; GO:0044802 (0.03) ! single-organism membrane organization; GO:0044765 (0.03) ! single-organism transport; GO:0044092 (0.03) ! negative regulation of molecular function; GO:0043627 (0.03) ! response to estrogen; GO:0035518 (0.03) ! histone H2A monoubiquitination; GO:0034244 (0.03) ! negative regulation of transcription elongation from RNA polymerase II promoter; GO:0033365 (0.03) ! protein localization to organelle; GO:0032651 (0.03) ! regulation of interleukin-1 beta production; GO:0032479 (0.03) ! regulation of type I interferon production; GO:0030154 (0.03) ! cell differentiation; GO:0022414 (0.03) ! reproductive process; GO:0018205 (0.03) ! peptidyl-lysine modification; GO:0015031 (0.03) ! protein transport; GO:0014070 (0.03) ! response to organic cyclic compound; GO:0010243 (0.03) ! response to organonitrogen compound; GO:0009725 (0.03) ! response to hormone; GO:0009411 (0.03) ! response to UV; GO:0006936 (0.03) ! muscle contraction; GO:0002683 (0.03) ! negative regulation of immune system process; GO:2001233 (0.02) ! regulation of apoptotic signaling pathway; GO:1903827 (0.02) ! regulation of cellular protein localization; GO:1902532 (0.02) ! negative regulation of intracellular signal transduction; GO:0090308 (0.02) ! regulation of methylation-dependent chromatin silencing; GO:0085020 (0.02) ! protein K6-linked ubiquitination; GO:0071310 (0.02) ! cellular response to organic substance; GO:0070507 (0.02) ! regulation of microtubule cytoskeleton organization; GO:0060416 (0.02) ! response to growth hormone; GO:0051494 (0.02) ! negative regulation of cytoskeleton organization; GO:0050790 (0.02) ! regulation of catalytic activity; GO:0050718 (0.02) ! positive regulation of interleukin-1 beta secretion; GO:0050710 (0.02) ! negative regulation of cytokine secretion; GO:0050688 (0.02) ! regulation of defense response to virus; GO:0048386 (0.02) ! positive regulation of retinoic acid receptor signaling pathway; GO:0046907 (0.02) ! intracellular transport; GO:0046598 (0.02) ! positive regulation of viral entry into host cell; GO:0045930 (0.02) ! negative regulation of mitotic cell cycle; GO:0045861 (0.02) ! negative regulation of proteolysis; GO:0045618 (0.02) ! positive regulation of keratinocyte differentiation; GO:0043967 (0.02) ! histone H4 acetylation; GO:0043966 (0.02) ! histone H3 acetylation; GO:0043523 (0.02) ! regulation of neuron apoptotic process; GO:0043486 (0.02) ! histone exchange; GO:0043254 (0.02) ! regulation of protein complex assembly; GO:0043065 (0.02) ! positive regulation of apoptotic process; GO:0036353 (0.02) ! histone H2A-K119 monoubiquitination; GO:0035372 (0.02) ! protein localization to microtubule; GO:0033523 (0.02) ! histone H2B ubiquitination; GO:0032940 (0.02) ! secretion by cell; GO:0032526 (0.02) ! response to retinoic acid; GO:0032481 (0.02) ! positive regulation of type I interferon production; GO:0032088 (0.02) ! negative regulation of NF-kappaB transcription factor activity; GO:0031648 (0.02) ! protein destabilization; GO:0031396 (0.02) ! regulation of protein ubiquitination; GO:0030218 (0.02) ! erythrocyte differentiation; GO:0030155 (0.02) ! regulation of cell adhesion; GO:0022402 (0.02) ! cell cycle process; GO:0016192 (0.02) ! vesicle-mediated transport; GO:0012501 (0.02) ! programmed cell death; GO:0010216 (0.02) ! maintenance of DNA methylation; GO:0008285 (0.02) ! negative regulation of cell proliferation; GO:0007517 (0.02) ! muscle organ development; GO:0007286 (0.02) ! spermatid development; GO:0007010 (0.02) ! cytoskeleton organization; GO:0006303 (0.02) ! double-strand break repair via nonhomologous end joining; GO:0001778 (0.02) ! plasma membrane repair; GO:2001235 (0.01) ! positive regulation of apoptotic signaling pathway; GO:2001234 (0.01) ! negative regulation of apoptotic signaling pathway; GO:2000679 (0.01) ! positive regulation of transcription regulatory region DNA binding; GO:2000378 (0.01) ! negative regulation of reactive oxygen species metabolic process; GO:2000059 (0.01) ! negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:1903895 (0.01) ! negative regulation of IRE1-mediated unfolded protein response; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:1901222 (0.01) ! regulation of NIK/NF-kappaB signaling; GO:1900226 (0.01) ! negative regulation of NLRP3 inflammasome complex assembly; GO:1900182 (0.01) ! positive regulation of protein localization to nucleus; GO:1900181 (0.01) ! negative regulation of protein localization to nucleus; GO:1900041 (0.01) ! negative regulation of interleukin-2 secretion; GO:0090281 (0.01) ! negative regulation of calcium ion import; GO:0090263 (0.01) ! positive regulation of canonical Wnt signaling pathway; GO:0090086 (0.01) ! negative regulation of protein deubiquitination; GO:0072643 (0.01) ! interferon-gamma secretion; GO:0071495 (0.01) ! cellular response to endogenous stimulus; GO:0071407 (0.01) ! cellular response to organic cyclic compound; GO:0060765 (0.01) ! regulation of androgen receptor signaling pathway; GO:0060627 (0.01) ! regulation of vesicle-mediated transport; GO:0060340 (0.01) ! positive regulation of type I interferon-mediated signaling pathway; GO:0060215 (0.01) ! primitive hemopoiesis; GO:0051384 (0.01) ! response to glucocorticoid; GO:0051345 (0.01) ! positive regulation of hydrolase activity; GO:0050767 (0.01) ! regulation of neurogenesis; GO:0048747 (0.01) ! muscle fiber development; GO:0048598 (0.01) ! embryonic morphogenesis; GO:0046716 (0.01) ! muscle cell cellular homeostasis; GO:0046683 (0.01) ! response to organophosphorus; GO:0046600 (0.01) ! negative regulation of centriole replication; GO:0046007 (0.01) ! negative regulation of activated T cell proliferation; GO:0045814 (0.01) ! negative regulation of gene expression, epigenetic; GO:0045785 (0.01) ! positive regulation of cell adhesion; GO:0045116 (0.01) ! protein neddylation; GO:0045071 (0.01) ! negative regulation of viral genome replication; GO:0043124 (0.01) ! negative regulation of I-kappaB kinase/NF-kappaB signaling; GO:0042147 (0.01) ! retrograde transport, endosome to Golgi; GO:0039535 (0.01) ! regulation of RIG-I signaling pathway; GO:0036503 (0.01) ! ERAD pathway; GO:0036352 (0.01) ! histone H2A-K15 ubiquitination; GO:0036351 (0.01) ! histone H2A-K13 ubiquitination; GO:0035458 (0.01) ! cellular response to interferon-beta; GO:0034660 (0.01) ! ncRNA metabolic process; GO:0034341 (0.01) ! response to interferon-gamma; GO:0034340 (0.01) ! response to type I interferon; GO:0034314 (0.01) ! Arp2/3 complex-mediated actin nucleation; GO:0033280 (0.01) ! response to vitamin D; GO:0033234 (0.01) ! negative regulation of protein sumoylation; GO:0033138 (0.01) ! positive regulation of peptidyl-serine phosphorylation; GO:0032874 (0.01) ! positive regulation of stress-activated MAPK cascade; GO:0032728 (0.01) ! positive regulation of interferon-beta production; GO:0032720 (0.01) ! negative regulation of tumor necrosis factor production; GO:0032608 (0.01) ! interferon-beta production; GO:0032496 (0.01) ! response to lipopolysaccharide; GO:0032480 (0.01) ! negative regulation of type I interferon production; GO:0032386 (0.01) ! regulation of intracellular transport; GO:0032102 (0.01) ! negative regulation of response to external stimulus; GO:0031398 (0.01) ! positive regulation of protein ubiquitination; GO:0031348 (0.01) ! negative regulation of defense response; GO:0031017 (0.01) ! exocrine pancreas development; GO:0030433 (0.01) ! ER-associated ubiquitin-dependent protein catabolic process; GO:0030239 (0.01) ! myofibril assembly; GO:0022603 (0.01) ! regulation of anatomical structure morphogenesis; GO:0022008 (0.01) ! neurogenesis; GO:0019985 (0.01) ! translesion synthesis; GO:0019827 (0.01) ! stem cell population maintenance; GO:0016925 (0.01) ! protein sumoylation; GO:0016558 (0.01) ! protein import into peroxisome matrix; GO:0016239 (0.01) ! positive regulation of macroautophagy; GO:0016050 (0.01) ! vesicle organization; GO:0014878 (0.01) ! response to electrical stimulus involved in regulation of muscle adaptation; GO:0010994 (0.01) ! free ubiquitin chain polymerization; GO:0010800 (0.01) ! positive regulation of peptidyl-threonine phosphorylation; GO:0010721 (0.01) ! negative regulation of cell development; GO:0010332 (0.01) ! response to gamma radiation; GO:0008283 (0.01) ! cell proliferation; GO:0007389 (0.01) ! pattern specification process; GO:0007093 (0.01) ! mitotic cell cycle checkpoint; GO:0007059 (0.01) ! chromosome segregation; GO:0007026 (0.01) ! negative regulation of microtubule depolymerization; GO:0007017 (0.01) ! microtubule-based process; GO:0006978 (0.01) ! DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; GO:0006941 (0.01) ! striated muscle contraction; GO:0006915 (0.01) ! apoptotic process; GO:0006914 (0.01) ! autophagy; GO:0006887 (0.01) ! exocytosis; GO:0006469 (0.01) ! negative regulation of protein kinase activity; GO:0006359 (0.01) ! regulation of transcription from RNA polymerase III promoter; GO:0002820 (0.01) ! negative regulation of adaptive immune response; GO:0002741 (0.01) ! positive regulation of cytokine secretion involved in immune response; GO:0002230 (0.01) ! positive regulation of defense response to virus by host; GO:0001666 (0.01) ! response to hypoxia; GO:0000077 (0.01) ! DNA damage checkpoint GO:0044464 (0.99) ! cell part; GO:0044424 (0.97) ! intracellular part; GO:0043226 (0.63) ! organelle; GO:0043229 (0.59) ! intracellular organelle; GO:0005737 (0.57) ! cytoplasm; GO:0043227 (0.52) ! membrane-bounded organelle; GO:0044444 (0.51) ! cytoplasmic part; GO:0044422 (0.51) ! organelle part; GO:0044446 (0.50) ! intracellular organelle part; GO:0032991 (0.49) ! macromolecular complex; GO:0043231 (0.46) ! intracellular membrane-bounded organelle; GO:0016020 (0.41) ! membrane; GO:0005634 (0.41) ! nucleus; GO:0005576 (0.41) ! extracellular region; GO:0043232 (0.38) ! intracellular non-membrane-bounded organelle; GO:0043234 (0.35) ! protein complex; GO:0044425 (0.33) ! membrane part; GO:0044428 (0.32) ! nuclear part; GO:0030529 (0.28) ! intracellular ribonucleoprotein complex; GO:1902494 (0.27) ! catalytic complex; GO:0031224 (0.27) ! intrinsic component of membrane; GO:0016021 (0.26) ! integral component of membrane; GO:0005622 (0.26) ! intracellular; GO:0000932 (0.26) ! cytoplasmic mRNA processing body; GO:1990234 (0.23) ! transferase complex; GO:0000151 (0.22) ! ubiquitin ligase complex; GO:0044231 (0.21) ! host cell presynaptic membrane; GO:0044221 (0.21) ! host cell synapse; GO:0044164 (0.21) ! host cell cytosol; GO:0044156 (0.21) ! host cell junction; GO:0030430 (0.21) ! host cell cytoplasm; GO:0020002 (0.21) ! host cell plasma membrane; GO:0031982 (0.20) ! vesicle; GO:0031410 (0.18) ! cytoplasmic vesicle; GO:0005886 (0.18) ! plasma membrane; GO:0005829 (0.18) ! cytosol; GO:0005654 (0.17) ! nucleoplasm; GO:0005773 (0.14) ! vacuole; GO:0005776 (0.13) ! autophagosome; GO:0044430 (0.12) ! cytoskeletal part; GO:1990462 (0.10) ! omegasome; GO:0000152 (0.10) ! nuclear ubiquitin ligase complex; GO:0031090 (0.09) ! organelle membrane; GO:0019005 (0.09) ! SCF ubiquitin ligase complex; GO:0042995 (0.08) ! cell projection; GO:0005874 (0.07) ! microtubule; GO:0044459 (0.06) ! plasma membrane part; GO:0042383 (0.06) ! sarcolemma; GO:0031436 (0.06) ! BRCA1-BARD1 complex; GO:0030659 (0.06) ! cytoplasmic vesicle membrane; GO:0005856 (0.06) ! cytoskeleton; GO:0098796 (0.05) ! membrane protein complex; GO:0070531 (0.05) ! BRCA1-A complex; GO:0044451 (0.05) ! nucleoplasm part; GO:0044427 (0.05) ! chromosomal part; GO:0005875 (0.05) ! microtubule associated complex; GO:1990060 (0.04) ! maltose transport complex; GO:0055052 (0.04) ! ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; GO:0044421 (0.04) ! extracellular region part; GO:0030288 (0.04) ! outer membrane-bounded periplasmic space; GO:0030027 (0.04) ! lamellipodium; GO:0016604 (0.04) ! nuclear body; GO:0005813 (0.04) ! centrosome; GO:0001726 (0.04) ! ruffle; GO:0031988 (0.03) ! membrane-bounded vesicle; GO:0030992 (0.03) ! intraciliary transport particle B; GO:0016605 (0.03) ! PML body; GO:0005929 (0.03) ! cilium; GO:0005720 (0.03) ! nuclear heterochromatin; GO:0098805 (0.02) ! whole membrane; GO:0098588 (0.02) ! bounding membrane of organelle; GO:0097505 (0.02) ! Rad6-Rad18 complex; GO:0070062 (0.02) ! extracellular exosome; GO:0035861 (0.02) ! site of double-strand break; GO:0035102 (0.02) ! PRC1 complex; GO:0005912 (0.02) ! adherens junction; GO:0005739 (0.02) ! mitochondrion; GO:0005730 (0.02) ! nucleolus; GO:0005694 (0.02) ! chromosome; GO:0071339 (0.01) ! MLL1 complex; GO:0044432 (0.01) ! endoplasmic reticulum part; GO:0033768 (0.01) ! SUMO-targeted ubiquitin ligase complex; GO:0031965 (0.01) ! nuclear membrane; GO:0030904 (0.01) ! retromer complex; GO:0030018 (0.01) ! Z disc; GO:0015630 (0.01) ! microtubule cytoskeleton; GO:0008385 (0.01) ! IkappaB kinase complex; GO:0008274 (0.01) ! gamma-tubulin ring complex; GO:0005925 (0.01) ! focal adhesion; GO:0005913 (0.01) ! cell-cell adherens junction; GO:0005887 (0.01) ! integral component of plasma membrane; GO:0005881 (0.01) ! cytoplasmic microtubule; GO:0005794 (0.01) ! Golgi apparatus; GO:0005783 (0.01) ! endoplasmic reticulum; GO:0005778 (0.01) ! peroxisomal membrane; GO:0005768 (0.01) ! endosome; GO:0005615 (0.01) ! extracellular space; GO:0000781 (0.01) ! chromosome, telomeric region; GO:0000139 (0.01) ! Golgi membrane GO:0005829 ! cytosol GO:0008270 ! zinc ion binding; GO:0005622 ! intracellular; GO:0046872 ! metal ion binding; GO:0005737 ! cytoplasm; GO:0005634 ! nucleus 4 GO:0008270 ! zinc ion binding 75874161-75878575 (17q25.1) Colon - Sigmoid: 107.70; Esophagus - Muscularis: 103.45; Uterus: 93.57; Artery - Coronary: 88.97; Artery - Aorta: 88.82; Nerve - Tibial: 85.15; Artery - Tibial: 85.11; Spleen: 83.52; Esophagus - Gastroesophageal Junction: 79.69; Vagina: 74.13; Bladder: 73.08; Cervix - Ectocervix: 70.08; Cervix - Endocervix: 69.11; Fallopian Tube: 67.36; Adipose - Subcutaneous: 66.47; Skin - Sun Exposed (Lower leg): 65.64; Kidney - Cortex: 62.55; Breast - Mammary Tissue: 59.55; Lung: 58.64; Minor Salivary Gland: 57.92; Adipose - Visceral (Omentum): 56.13; Colon - Transverse: 54.40; Prostate: 54.37; Skin - Not Sun Exposed (Suprapubic): 51.90; Thyroid: 46.51; Small Intestine - Terminal Ileum: 44.42; Brain - Cerebellum: 43.46; Esophagus - Mucosa: 42.84; Brain - Cerebellar Hemisphere: 34.85; Stomach: 32.65; Brain - Substantia nigra: 31.42; Brain - Cortex: 30.84; Brain - Hypothalamus: 26.32; Brain - Caudate (basal ganglia): 26.04; Brain - Spinal cord (cervical c-1): 25.95; Pituitary: 25.65; Brain - Putamen (basal ganglia): 25.08; Brain - Frontal Cortex (BA9): 24.45; Brain - Amygdala: 24.20; Brain - Anterior cingulate cortex (BA24): 24.18; Testis: 23.26; Brain - Hippocampus: 22.74; Adrenal Gland: 21.84; Brain - Nucleus accumbens (basal ganglia): 21.40; Ovary: 20.87; Heart - Atrial Appendage: 20.63; Liver: 17.68; Heart - Left Ventricle: 16.83; Cells - Transformed fibroblasts: 14.93; Pancreas: 12.18; Muscle - Skeletal: 7.60; Cells - EBV-transformed lymphocytes: 2.86; Whole Blood: 1.38; MDGSGPFSCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQLRKNHTLSELLQLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEPVRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHLRPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGIAQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRRQEEQRSRLSRARQNLSQVPEADSVSFLQELLALRLALEDGCGPGPGPPRELSFTKSSQAVRAVRDMLAVACVNQWEQLRGPGGNEDGPQKLDSEADAEPQDLESTNLLESEAPRDYFLKFAYIVDLDSDTADKFLQLFGTKGVKRVLCPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIEGWVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVGVCLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRLKPAFFLESVDAHLQIGPLKKSCISVLKRR UBALD2 UBA-like domain-containing protein 2 UBAD2_HUMAN (Q8IYN6-1) GO:0003824 (0.65) ! catalytic activity; GO:1901363 (0.46) ! heterocyclic compound binding; GO:0097159 (0.46) ! organic cyclic compound binding; GO:0043169 (0.41) ! cation binding; GO:0016491 (0.40) ! oxidoreductase activity; GO:0046906 (0.39) ! tetrapyrrole binding; GO:0016684 (0.39) ! oxidoreductase activity, acting on peroxide as acceptor; GO:0016209 (0.39) ! antioxidant activity; GO:0016772 (0.28) ! transferase activity, transferring phosphorus-containing groups; GO:0016779 (0.26) ! nucleotidyltransferase activity; GO:0001055 (0.25) ! RNA polymerase II activity; GO:0016787 (0.12) ! hydrolase activity; GO:0003676 (0.11) ! nucleic acid binding; GO:0001104 (0.11) ! RNA polymerase II transcription cofactor activity; GO:0003723 (0.09) ! RNA binding; GO:0019899 (0.06) ! enzyme binding; GO:0017111 (0.06) ! nucleoside-triphosphatase activity; GO:0046873 (0.05) ! metal ion transmembrane transporter activity; GO:0044877 (0.05) ! macromolecular complex binding; GO:0044822 (0.05) ! poly(A) RNA binding; GO:0005261 (0.05) ! cation channel activity; GO:0022843 (0.04) ! voltage-gated cation channel activity; GO:0016887 (0.04) ! ATPase activity; GO:0008289 (0.04) ! lipid binding; GO:0005509 (0.04) ! calcium ion binding; GO:0005262 (0.04) ! calcium channel activity; GO:0003677 (0.04) ! DNA binding; GO:0044212 (0.03) ! transcription regulatory region DNA binding; GO:0016788 (0.03) ! hydrolase activity, acting on ester bonds; GO:0008331 (0.03) ! high voltage-gated calcium channel activity; GO:0005543 (0.03) ! phospholipid binding; GO:0005102 (0.03) ! receptor binding; GO:0004872 (0.03) ! receptor activity; GO:0003777 (0.03) ! microtubule motor activity; GO:0003682 (0.03) ! chromatin binding; GO:0098772 (0.02) ! molecular function regulator; GO:0070011 (0.02) ! peptidase activity, acting on L-amino acid peptides; GO:0042802 (0.02) ! identical protein binding; GO:0032403 (0.02) ! protein complex binding; GO:0031625 (0.02) ! ubiquitin protein ligase binding; GO:0019901 (0.02) ! protein kinase binding; GO:0008092 (0.02) ! cytoskeletal protein binding; GO:0005544 (0.02) ! calcium-dependent phospholipid binding; GO:0005522 (0.02) ! profilin binding; GO:0005198 (0.02) ! structural molecule activity; GO:0004871 (0.02) ! signal transducer activity; GO:0004674 (0.02) ! protein serine/threonine kinase activity; GO:0003924 (0.02) ! GTPase activity; GO:0003713 (0.02) ! transcription coactivator activity; GO:0001191 (0.02) ! transcriptional repressor activity, RNA polymerase II transcription factor binding; GO:1990841 (0.01) ! promoter-specific chromatin binding; GO:1901681 (0.01) ! sulfur compound binding; GO:0097367 (0.01) ! carbohydrate derivative binding; GO:0097200 (0.01) ! cysteine-type endopeptidase activity involved in execution phase of apoptosis; GO:0071949 (0.01) ! FAD binding; GO:0071889 (0.01) ! 14-3-3 protein binding; GO:0052689 (0.01) ! carboxylic ester hydrolase activity; GO:0050998 (0.01) ! nitric-oxide synthase binding; GO:0050839 (0.01) ! cell adhesion molecule binding; GO:0050265 (0.01) ! RNA uridylyltransferase activity; GO:0048306 (0.01) ! calcium-dependent protein binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0044548 (0.01) ! S100 protein binding; GO:0042809 (0.01) ! vitamin D receptor binding; GO:0042043 (0.01) ! neurexin family protein binding; GO:0035612 (0.01) ! AP-2 adaptor complex binding; GO:0033040 (0.01) ! sour taste receptor activity; GO:0031749 (0.01) ! D2 dopamine receptor binding; GO:0031432 (0.01) ! titin binding; GO:0030506 (0.01) ! ankyrin binding; GO:0030374 (0.01) ! ligand-dependent nuclear receptor transcription coactivator activity; GO:0023026 (0.01) ! MHC class II protein complex binding; GO:0017056 (0.01) ! structural constituent of nuclear pore; GO:0016722 (0.01) ! oxidoreductase activity, oxidizing metal ions; GO:0016709 (0.01) ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; GO:0009931 (0.01) ! calcium-dependent protein serine/threonine kinase activity; GO:0008536 (0.01) ! Ran GTPase binding; GO:0008429 (0.01) ! phosphatidylethanolamine binding; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008094 (0.01) ! DNA-dependent ATPase activity; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005516 (0.01) ! calmodulin binding; GO:0005507 (0.01) ! copper ion binding; GO:0005249 (0.01) ! voltage-gated potassium channel activity; GO:0005096 (0.01) ! GTPase activator activity; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0004969 (0.01) ! histamine receptor activity; GO:0004702 (0.01) ! receptor signaling protein serine/threonine kinase activity; GO:0004683 (0.01) ! calmodulin-dependent protein kinase activity; GO:0004620 (0.01) ! phospholipase activity; GO:0004525 (0.01) ! ribonuclease III activity; GO:0004407 (0.01) ! histone deacetylase activity; GO:0004386 (0.01) ! helicase activity; GO:0004198 (0.01) ! calcium-dependent cysteine-type endopeptidase activity; GO:0004185 (0.01) ! serine-type carboxypeptidase activity; GO:0003910 (0.01) ! DNA ligase (ATP) activity; GO:0003779 (0.01) ! actin binding; GO:0003725 (0.01) ! double-stranded RNA binding; GO:0001222 (0.01) ! transcription corepressor binding; GO:0001106 (0.01) ! RNA polymerase II transcription corepressor activity; GO:0001105 (0.01) ! RNA polymerase II transcription coactivator activity; GO:0001047 (0.01) ! core promoter binding; GO:0000981 (0.01) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:0000978 (0.01) ! RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0009987 (0.81) ! cellular process; GO:0044699 (0.73) ! single-organism process; GO:0008152 (0.64) ! metabolic process; GO:0044237 (0.62) ! cellular metabolic process; GO:0044248 (0.53) ! cellular catabolic process; GO:0044763 (0.49) ! single-organism cellular process; GO:0050896 (0.44) ! response to stimulus; GO:0065007 (0.43) ! biological regulation; GO:0044710 (0.41) ! single-organism metabolic process; GO:0006950 (0.41) ! response to stress; GO:1990748 (0.39) ! cellular detoxification; GO:0050794 (0.39) ! regulation of cellular process; GO:0044238 (0.39) ! primary metabolic process; GO:0043170 (0.39) ! macromolecule metabolic process; GO:0042743 (0.39) ! hydrogen peroxide metabolic process; GO:0044260 (0.38) ! cellular macromolecule metabolic process; GO:0016043 (0.38) ! cellular component organization; GO:0006996 (0.29) ! organelle organization; GO:0019538 (0.27) ! protein metabolic process; GO:0051603 (0.22) ! proteolysis involved in cellular protein catabolic process; GO:0044265 (0.22) ! cellular macromolecule catabolic process; GO:0006998 (0.22) ! nuclear envelope organization; GO:0051179 (0.18) ! localization; GO:0031323 (0.17) ! regulation of cellular metabolic process; GO:0006810 (0.17) ! transport; GO:0007165 (0.16) ! signal transduction; GO:0048519 (0.13) ! negative regulation of biological process; GO:0080090 (0.12) ! regulation of primary metabolic process; GO:0048523 (0.12) ! negative regulation of cellular process; GO:0048518 (0.12) ! positive regulation of biological process; GO:0044767 (0.12) ! single-organism developmental process; GO:0016070 (0.12) ! RNA metabolic process; GO:0009892 (0.12) ! negative regulation of metabolic process; GO:0051641 (0.11) ! cellular localization; GO:0051252 (0.11) ! regulation of RNA metabolic process; GO:0048522 (0.11) ! positive regulation of cellular process; GO:0031324 (0.11) ! negative regulation of cellular metabolic process; GO:0030518 (0.11) ! intracellular steroid hormone receptor signaling pathway; GO:0010468 (0.11) ! regulation of gene expression; GO:0032501 (0.10) ! multicellular organismal process; GO:0009889 (0.10) ! regulation of biosynthetic process; GO:0051649 (0.09) ! establishment of localization in cell; GO:0006355 (0.09) ! regulation of transcription, DNA-templated; GO:0051254 (0.08) ! positive regulation of RNA metabolic process; GO:0046907 (0.08) ! intracellular transport; GO:0044707 (0.08) ! single-multicellular organism process; GO:0016192 (0.08) ! vesicle-mediated transport; GO:0010628 (0.08) ! positive regulation of gene expression; GO:1902680 (0.07) ! positive regulation of RNA biosynthetic process; GO:0065008 (0.07) ! regulation of biological quality; GO:0050790 (0.07) ! regulation of catalytic activity; GO:0048856 (0.07) ! anatomical structure development; GO:0044765 (0.07) ! single-organism transport; GO:0043933 (0.07) ! macromolecular complex subunit organization; GO:0006928 (0.07) ! movement of cell or subcellular component; GO:0051336 (0.06) ! regulation of hydrolase activity; GO:0045936 (0.06) ! negative regulation of phosphate metabolic process; GO:0045893 (0.06) ! positive regulation of transcription, DNA-templated; GO:0043086 (0.06) ! negative regulation of catalytic activity; GO:0032774 (0.06) ! RNA biosynthetic process; GO:0010629 (0.06) ! negative regulation of gene expression; GO:0009653 (0.06) ! anatomical structure morphogenesis; GO:0008104 (0.06) ! protein localization; GO:0006396 (0.06) ! RNA processing; GO:0006357 (0.06) ! regulation of transcription from RNA polymerase II promoter; GO:0071702 (0.05) ! organic substance transport; GO:0051049 (0.05) ! regulation of transport; GO:0045944 (0.05) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045892 (0.05) ! negative regulation of transcription, DNA-templated; GO:0040011 (0.05) ! locomotion; GO:0022607 (0.05) ! cellular component assembly; GO:0016071 (0.05) ! mRNA metabolic process; GO:0010923 (0.05) ! negative regulation of phosphatase activity; GO:0007155 (0.05) ! cell adhesion; GO:0007018 (0.05) ! microtubule-based movement; GO:0007010 (0.05) ! cytoskeleton organization; GO:0006464 (0.05) ! cellular protein modification process; GO:0003008 (0.05) ! system process; GO:1903530 (0.04) ! regulation of secretion by cell; GO:0051716 (0.04) ! cellular response to stimulus; GO:0050877 (0.04) ! neurological system process; GO:0048869 (0.04) ! cellular developmental process; GO:0048729 (0.04) ! tissue morphogenesis; GO:0048598 (0.04) ! embryonic morphogenesis; GO:0046903 (0.04) ! secretion; GO:0044702 (0.04) ! single organism reproductive process; GO:0042391 (0.04) ! regulation of membrane potential; GO:0034660 (0.04) ! ncRNA metabolic process; GO:0023051 (0.04) ! regulation of signaling; GO:0016337 (0.04) ! single organismal cell-cell adhesion; GO:0010646 (0.04) ! regulation of cell communication; GO:0009792 (0.04) ! embryo development ending in birth or egg hatching; GO:0007626 (0.04) ! locomotory behavior; GO:0007154 (0.04) ! cell communication; GO:0006886 (0.04) ! intracellular protein transport; GO:0006366 (0.04) ! transcription from RNA polymerase II promoter; GO:0006325 (0.04) ! chromatin organization; GO:0002376 (0.04) ! immune system process; GO:0000398 (0.04) ! mRNA splicing, via spliceosome; GO:0000122 (0.04) ! negative regulation of transcription from RNA polymerase II promoter; GO:1902589 (0.03) ! single-organism organelle organization; GO:1902580 (0.03) ! single-organism cellular localization; GO:0086010 (0.03) ! membrane depolarization during action potential; GO:0071822 (0.03) ! protein complex subunit organization; GO:0060627 (0.03) ! regulation of vesicle-mediated transport; GO:0051128 (0.03) ! regulation of cellular component organization; GO:0043484 (0.03) ! regulation of RNA splicing; GO:0043009 (0.03) ! chordate embryonic development; GO:0042221 (0.03) ! response to chemical; GO:0042110 (0.03) ! T cell activation; GO:0036269 (0.03) ! swimming behavior; GO:0033365 (0.03) ! protein localization to organelle; GO:0032940 (0.03) ! secretion by cell; GO:0030705 (0.03) ! cytoskeleton-dependent intracellular transport; GO:0009887 (0.03) ! organ morphogenesis; GO:0007600 (0.03) ! sensory perception; GO:0007274 (0.03) ! neuromuscular synaptic transmission; GO:0006897 (0.03) ! endocytosis; GO:0006888 (0.03) ! ER to Golgi vesicle-mediated transport; GO:0006368 (0.03) ! transcription elongation from RNA polymerase II promoter; GO:0006259 (0.03) ! DNA metabolic process; GO:0003006 (0.03) ! developmental process involved in reproduction; GO:0001966 (0.03) ! thigmotaxis; GO:0099531 (0.02) ! presynaptic process involved in chemical synaptic transmission; GO:0071705 (0.02) ! nitrogen compound transport; GO:0070278 (0.02) ! extracellular matrix constituent secretion; GO:0061061 (0.02) ! muscle structure development; GO:0060536 (0.02) ! cartilage morphogenesis; GO:0060026 (0.02) ! convergent extension; GO:0051704 (0.02) ! multi-organism process; GO:0051050 (0.02) ! positive regulation of transport; GO:0050767 (0.02) ! regulation of neurogenesis; GO:0050684 (0.02) ! regulation of mRNA processing; GO:0050434 (0.02) ! positive regulation of viral transcription; GO:0048731 (0.02) ! system development; GO:0048703 (0.02) ! embryonic viscerocranium morphogenesis; GO:0048513 (0.02) ! animal organ development; GO:0048468 (0.02) ! cell development; GO:0040008 (0.02) ! regulation of growth; GO:0040007 (0.02) ! growth; GO:0033120 (0.02) ! positive regulation of RNA splicing; GO:0032786 (0.02) ! positive regulation of DNA-templated transcription, elongation; GO:0032785 (0.02) ! negative regulation of DNA-templated transcription, elongation; GO:0031344 (0.02) ! regulation of cell projection organization; GO:0031054 (0.02) ! pre-miRNA processing; GO:0030154 (0.02) ! cell differentiation; GO:0030036 (0.02) ! actin cytoskeleton organization; GO:0030031 (0.02) ! cell projection assembly; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0022411 (0.02) ! cellular component disassembly; GO:0019827 (0.02) ! stem cell population maintenance; GO:0017157 (0.02) ! regulation of exocytosis; GO:0016477 (0.02) ! cell migration; GO:0010817 (0.02) ! regulation of hormone levels; GO:0010033 (0.02) ! response to organic substance; GO:0009966 (0.02) ! regulation of signal transduction; GO:0009628 (0.02) ! response to abiotic stimulus; GO:0007416 (0.02) ! synapse assembly; GO:0007346 (0.02) ! regulation of mitotic cell cycle; GO:0007169 (0.02) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0006974 (0.02) ! cellular response to DNA damage stimulus; GO:0006898 (0.02) ! receptor-mediated endocytosis; GO:0006812 (0.02) ! cation transport; GO:0006606 (0.02) ! protein import into nucleus; GO:0006468 (0.02) ! protein phosphorylation; GO:0006461 (0.02) ! protein complex assembly; GO:0006370 (0.02) ! 7-methylguanosine mRNA capping; GO:0006367 (0.02) ! transcription initiation from RNA polymerase II promoter; GO:0006353 (0.02) ! DNA-templated transcription, termination; GO:0006338 (0.02) ! chromatin remodeling; GO:2000369 (0.01) ! regulation of clathrin-mediated endocytosis; GO:1903423 (0.01) ! positive regulation of synaptic vesicle recycling; GO:1901998 (0.01) ! toxin transport; GO:1900364 (0.01) ! negative regulation of mRNA polyadenylation; GO:0098779 (0.01) ! mitophagy in response to mitochondrial depolarization; GO:0097194 (0.01) ! execution phase of apoptosis; GO:0090675 (0.01) ! intermicrovillar adhesion; GO:0090526 (0.01) ! regulation of gluconeogenesis involved in cellular glucose homeostasis; GO:0090502 (0.01) ! RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0071468 (0.01) ! cellular response to acidic pH; GO:0071453 (0.01) ! cellular response to oxygen levels; GO:0071044 (0.01) ! histone mRNA catabolic process; GO:0070973 (0.01) ! protein localization to endoplasmic reticulum exit site; GO:0060429 (0.01) ! epithelium development; GO:0060411 (0.01) ! cardiac septum morphogenesis; GO:0060384 (0.01) ! innervation; GO:0060324 (0.01) ! face development; GO:0060173 (0.01) ! limb development; GO:0060123 (0.01) ! regulation of growth hormone secretion; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0060021 (0.01) ! palate development; GO:0055114 (0.01) ! oxidation-reduction process; GO:0051932 (0.01) ! synaptic transmission, GABAergic; GO:0051666 (0.01) ! actin cortical patch localization; GO:0051592 (0.01) ! response to calcium ion; GO:0051262 (0.01) ! protein tetramerization; GO:0051103 (0.01) ! DNA ligation involved in DNA repair; GO:0051056 (0.01) ! regulation of small GTPase mediated signal transduction; GO:0050982 (0.01) ! detection of mechanical stimulus; GO:0050915 (0.01) ! sensory perception of sour taste; GO:0050890 (0.01) ! cognition; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0050770 (0.01) ! regulation of axonogenesis; GO:0048752 (0.01) ! semicircular canal morphogenesis; GO:0048747 (0.01) ! muscle fiber development; GO:0048208 (0.01) ! COPII vesicle coating; GO:0048013 (0.01) ! ephrin receptor signaling pathway; GO:0046847 (0.01) ! filopodium assembly; GO:0046777 (0.01) ! protein autophosphorylation; GO:0045956 (0.01) ! positive regulation of calcium ion-dependent exocytosis; GO:0045920 (0.01) ! negative regulation of exocytosis; GO:0045747 (0.01) ! positive regulation of Notch signaling pathway; GO:0045214 (0.01) ! sarcomere organization; GO:0044258 (0.01) ! intestinal lipid catabolic process; GO:0044241 (0.01) ! lipid digestion; GO:0043584 (0.01) ! nose development; GO:0043581 (0.01) ! mycelium development; GO:0043087 (0.01) ! regulation of GTPase activity; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0043010 (0.01) ! camera-type eye development; GO:0042795 (0.01) ! snRNA transcription from RNA polymerase II promoter; GO:0042789 (0.01) ! mRNA transcription from RNA polymerase II promoter; GO:0042472 (0.01) ! inner ear morphogenesis; GO:0042471 (0.01) ! ear morphogenesis; GO:0042048 (0.01) ! olfactory behavior; GO:0040018 (0.01) ! positive regulation of multicellular organism growth; GO:0039692 (0.01) ! single stranded viral RNA replication via double stranded DNA intermediate; GO:0036309 (0.01) ! protein localization to M-band; GO:0036302 (0.01) ! atrioventricular canal development; GO:0036180 (0.01) ! filamentous growth of a population of unicellular organisms in response to biotic stimulus; GO:0035909 (0.01) ! aorta morphogenesis; GO:0035904 (0.01) ! aorta development; GO:0035418 (0.01) ! protein localization to synapse; GO:0035176 (0.01) ! social behavior; GO:0035116 (0.01) ! embryonic hindlimb morphogenesis; GO:0035019 (0.01) ! somatic stem cell population maintenance; GO:0034587 (0.01) ! piRNA metabolic process; GO:0034244 (0.01) ! negative regulation of transcription elongation from RNA polymerase II promoter; GO:0034220 (0.01) ! ion transmembrane transport; GO:0033132 (0.01) ! negative regulation of glucokinase activity; GO:0032968 (0.01) ! positive regulation of transcription elongation from RNA polymerase II promoter; GO:0032532 (0.01) ! regulation of microvillus length; GO:0031505 (0.01) ! fungal-type cell wall organization; GO:0031123 (0.01) ! RNA 3'-end processing; GO:0031053 (0.01) ! primary miRNA processing; GO:0031047 (0.01) ! gene silencing by RNA; GO:0030540 (0.01) ! female genitalia development; GO:0030521 (0.01) ! androgen receptor signaling pathway; GO:0030448 (0.01) ! hyphal growth; GO:0030422 (0.01) ! production of siRNA involved in RNA interference; GO:0030308 (0.01) ! negative regulation of cell growth; GO:0030299 (0.01) ! intestinal cholesterol absorption; GO:0030260 (0.01) ! entry into host cell; GO:0030217 (0.01) ! T cell differentiation; GO:0030157 (0.01) ! pancreatic juice secretion; GO:0030097 (0.01) ! hemopoiesis; GO:0030073 (0.01) ! insulin secretion; GO:0030042 (0.01) ! actin filament depolymerization; GO:0021954 (0.01) ! central nervous system neuron development; GO:0021772 (0.01) ! olfactory bulb development; GO:0021591 (0.01) ! ventricular system development; GO:0021553 (0.01) ! olfactory nerve development; GO:0019933 (0.01) ! cAMP-mediated signaling; GO:0019886 (0.01) ! antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0019233 (0.01) ! sensory perception of pain; GO:0018350 (0.01) ! protein esterification; GO:0018105 (0.01) ! peptidyl-serine phosphorylation; GO:0016925 (0.01) ! protein sumoylation; GO:0016575 (0.01) ! histone deacetylation; GO:0016540 (0.01) ! protein autoprocessing; GO:0016239 (0.01) ! positive regulation of macroautophagy; GO:0016080 (0.01) ! synaptic vesicle targeting; GO:0016079 (0.01) ! synaptic vesicle exocytosis; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0010927 (0.01) ! cellular component assembly involved in morphogenesis; GO:0010880 (0.01) ! regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; GO:0010587 (0.01) ! miRNA catabolic process; GO:0010501 (0.01) ! RNA secondary structure unwinding; GO:0010467 (0.01) ! gene expression; GO:0009738 (0.01) ! abscisic acid-activated signaling pathway; GO:0009405 (0.01) ! pathogenesis; GO:0009062 (0.01) ! fatty acid catabolic process; GO:0008543 (0.01) ! fibroblast growth factor receptor signaling pathway; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008015 (0.01) ! blood circulation; GO:0007628 (0.01) ! adult walking behavior; GO:0007605 (0.01) ! sensory perception of sound; GO:0007512 (0.01) ! adult heart development; GO:0007420 (0.01) ! brain development; GO:0007417 (0.01) ! central nervous system development; GO:0007369 (0.01) ! gastrulation; GO:0007298 (0.01) ! border follicle cell migration; GO:0007286 (0.01) ! spermatid development; GO:0007158 (0.01) ! neuron cell-cell adhesion; GO:0007095 (0.01) ! mitotic G2 DNA damage checkpoint; GO:0007049 (0.01) ! cell cycle; GO:0007032 (0.01) ! endosome organization; GO:0006955 (0.01) ! immune response; GO:0006816 (0.01) ! calcium ion transport; GO:0006707 (0.01) ! cholesterol catabolic process; GO:0006641 (0.01) ! triglyceride metabolic process; GO:0006607 (0.01) ! NLS-bearing protein import into nucleus; GO:0006605 (0.01) ! protein targeting; GO:0006406 (0.01) ! mRNA export from nucleus; GO:0006283 (0.01) ! transcription-coupled nucleotide-excision repair; GO:0006273 (0.01) ! lagging strand elongation; GO:0003226 (0.01) ! right ventricular compact myocardium morphogenesis; GO:0003222 (0.01) ! ventricular trabecula myocardium morphogenesis; GO:0003007 (0.01) ! heart morphogenesis; GO:0002474 (0.01) ! antigen processing and presentation of peptide antigen via MHC class I; GO:0002312 (0.01) ! B cell activation involved in immune response; GO:0002031 (0.01) ! G-protein coupled receptor internalization; GO:0001974 (0.01) ! blood vessel remodeling; GO:0001764 (0.01) ! neuron migration; GO:0001701 (0.01) ! in utero embryonic development; GO:0001581 (0.01) ! detection of chemical stimulus involved in sensory perception of sour taste; GO:0001501 (0.01) ! skeletal system development; GO:0000389 (0.01) ! mRNA 3'-splice site recognition; GO:0000381 (0.01) ! regulation of alternative mRNA splicing, via spliceosome GO:0044464 (0.99) ! cell part; GO:0044424 (0.96) ! intracellular part; GO:0043226 (0.73) ! organelle; GO:0043227 (0.71) ! membrane-bounded organelle; GO:0043229 (0.70) ! intracellular organelle; GO:0043231 (0.67) ! intracellular membrane-bounded organelle; GO:0044444 (0.64) ! cytoplasmic part; GO:0044422 (0.62) ! organelle part; GO:0044446 (0.61) ! intracellular organelle part; GO:0005576 (0.55) ! extracellular region; GO:0032991 (0.46) ! macromolecular complex; GO:0043234 (0.44) ! protein complex; GO:0005634 (0.43) ! nucleus; GO:0044428 (0.42) ! nuclear part; GO:0044451 (0.36) ! nucleoplasm part; GO:0005737 (0.31) ! cytoplasm; GO:0005829 (0.30) ! cytosol; GO:1902494 (0.25) ! catalytic complex; GO:1990234 (0.24) ! transferase complex; GO:0005665 (0.23) ! DNA-directed RNA polymerase II, core complex; GO:0016020 (0.17) ! membrane; GO:0044429 (0.14) ! mitochondrial part; GO:0044425 (0.13) ! membrane part; GO:0031988 (0.11) ! membrane-bounded vesicle; GO:0031224 (0.11) ! intrinsic component of membrane; GO:0043232 (0.10) ! intracellular non-membrane-bounded organelle; GO:0016592 (0.09) ! mediator complex; GO:0070847 (0.08) ! core mediator complex; GO:0070062 (0.08) ! extracellular exosome; GO:0031984 (0.08) ! organelle subcompartment; GO:0005794 (0.08) ! Golgi apparatus; GO:0005773 (0.08) ! vacuole; GO:0044430 (0.07) ! cytoskeletal part; GO:0031304 (0.07) ! intrinsic component of mitochondrial inner membrane; GO:0009543 (0.07) ! chloroplast thylakoid lumen; GO:0009535 (0.07) ! chloroplast thylakoid membrane; GO:0009534 (0.07) ! chloroplast thylakoid; GO:0009507 (0.07) ! chloroplast; GO:0005886 (0.07) ! plasma membrane; GO:0005783 (0.07) ! endoplasmic reticulum; GO:0005759 (0.07) ! mitochondrial matrix; GO:0005758 (0.07) ! mitochondrial intermembrane space; GO:0005739 (0.07) ! mitochondrion; GO:0005654 (0.06) ! nucleoplasm; GO:0097458 (0.05) ! neuron part; GO:0045202 (0.04) ! synapse; GO:0016023 (0.04) ! cytoplasmic, membrane-bounded vesicle; GO:0005887 (0.04) ! integral component of plasma membrane; GO:0005875 (0.04) ! microtubule associated complex; GO:0044463 (0.03) ! cell projection part; GO:0044456 (0.03) ! synapse part; GO:0044454 (0.03) ! nuclear chromosome part; GO:0042995 (0.03) ! cell projection; GO:0030133 (0.03) ! transport vesicle; GO:0005871 (0.03) ! kinesin complex; GO:0005856 (0.03) ! cytoskeleton; GO:0098796 (0.02) ! membrane protein complex; GO:0071004 (0.02) ! U2-type prespliceosome; GO:0044448 (0.02) ! cell cortex part; GO:0043005 (0.02) ! neuron projection; GO:0032044 (0.02) ! DSIF complex; GO:0030496 (0.02) ! midbody; GO:0030134 (0.02) ! ER to Golgi transport vesicle; GO:0009986 (0.02) ! cell surface; GO:0005819 (0.02) ! spindle; GO:0005730 (0.02) ! nucleolus; GO:0005685 (0.02) ! U1 snRNP; GO:0005615 (0.02) ! extracellular space; GO:0000974 (0.02) ! Prp19 complex; GO:0000790 (0.02) ! nuclear chromatin; GO:1990023 (0.01) ! mitotic spindle midzone; GO:0097470 (0.01) ! ribbon synapse; GO:0097431 (0.01) ! mitotic spindle pole; GO:0072686 (0.01) ! mitotic spindle; GO:0071565 (0.01) ! nBAF complex; GO:0071564 (0.01) ! npBAF complex; GO:0060077 (0.01) ! inhibitory synapse; GO:0048788 (0.01) ! cytoskeleton of presynaptic active zone; GO:0048786 (0.01) ! presynaptic active zone; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0045335 (0.01) ! phagocytic vesicle; GO:0045121 (0.01) ! membrane raft; GO:0045111 (0.01) ! intermediate filament cytoskeleton; GO:0044317 (0.01) ! rod spherule; GO:0044316 (0.01) ! cone cell pedicle; GO:0044214 (0.01) ! spanning component of plasma membrane; GO:0043235 (0.01) ! receptor complex; GO:0043197 (0.01) ! dendritic spine; GO:0043196 (0.01) ! varicosity; GO:0043195 (0.01) ! terminal bouton; GO:0043025 (0.01) ! neuronal cell body; GO:0042582 (0.01) ! azurophil granule; GO:0042581 (0.01) ! specific granule; GO:0034703 (0.01) ! cation channel complex; GO:0032221 (0.01) ! Rpd3S complex; GO:0031594 (0.01) ! neuromuscular junction; GO:0031528 (0.01) ! microvillus membrane; GO:0031526 (0.01) ! brush border membrane; GO:0031430 (0.01) ! M band; GO:0031080 (0.01) ! nuclear pore outer ring; GO:0030426 (0.01) ! growth cone; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030312 (0.01) ! external encapsulating structure; GO:0030127 (0.01) ! COPII vesicle coat; GO:0030018 (0.01) ! Z disc; GO:0030016 (0.01) ! myofibril; GO:0016514 (0.01) ! SWI/SNF complex; GO:0016324 (0.01) ! apical plasma membrane; GO:0014069 (0.01) ! postsynaptic density; GO:0012507 (0.01) ! ER to Golgi transport vesicle membrane; GO:0008021 (0.01) ! synaptic vesicle; GO:0005905 (0.01) ! clathrin-coated pit; GO:0005813 (0.01) ! centrosome; GO:0005802 (0.01) ! trans-Golgi network; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005719 (0.01) ! nuclear euchromatin; GO:0005635 (0.01) ! nuclear envelope 2 76265202-76271299 (17q25.1) Whole Blood: 205.60; Cells - EBV-transformed lymphocytes: 187.70; Spleen: 82.09; Lung: 78.72; Esophagus - Mucosa: 72.39; Muscle - Skeletal: 65.42; Small Intestine - Terminal Ileum: 64.23; Skin - Not Sun Exposed (Suprapubic): 63.97; Skin - Sun Exposed (Lower leg): 61.47; Nerve - Tibial: 58.06; Minor Salivary Gland: 52.82; Breast - Mammary Tissue: 48.19; Vagina: 47.25; Adipose - Subcutaneous: 46.07; Cells - Transformed fibroblasts: 44.98; Colon - Transverse: 44.66; Fallopian Tube: 43.82; Thyroid: 43.62; Prostate: 41.97; Bladder: 41.37; Adipose - Visceral (Omentum): 40.88; Stomach: 40.66; Artery - Aorta: 37.25; Artery - Coronary: 36.20; Brain - Spinal cord (cervical c-1): 33.42; Colon - Sigmoid: 29.45; Artery - Tibial: 28.94; Esophagus - Muscularis: 28.60; Esophagus - Gastroesophageal Junction: 28.32; Cervix - Endocervix: 27.01; Uterus: 26.81; Cervix - Ectocervix: 26.11; Kidney - Cortex: 26.11; Testis: 25.34; Pituitary: 23.77; Brain - Cerebellum: 22.74; Brain - Substantia nigra: 22.02; Brain - Hypothalamus: 21.59; Brain - Cerebellar Hemisphere: 21.06; Brain - Frontal Cortex (BA9): 20.79; Ovary: 20.72; Brain - Cortex: 20.50; Brain - Hippocampus: 18.25; Heart - Atrial Appendage: 18.13; Pancreas: 17.61; Brain - Anterior cingulate cortex (BA24): 17.59; Brain - Nucleus accumbens (basal ganglia): 17.21; Brain - Amygdala: 16.99; Brain - Caudate (basal ganglia): 16.68; Adrenal Gland: 15.81; Brain - Putamen (basal ganglia): 15.63; Heart - Left Ventricle: 15.00; Liver: 12.54; MSVNMDELRHQVMINQFVLAAGCAADQAKQLLQAAHWQFETALSTFFQETNIPNSHHHHQMMCTPSNTPATPPNFPDALAMFSKLRASEGLQSSNSPMTAAACSPPANFSPFWASSPPSHQAPWIPPSSPTTFHHLHRPQPTWPPGAQQGGAQQKAMAAMDGQR QRICH2 Glutamine-rich protein 2 QRIC2_HUMAN (Q9H0J4-1) GO:0003824 (0.38) ! catalytic activity; GO:0016787 (0.29) ! hydrolase activity; GO:0017111 (0.26) ! nucleoside-triphosphatase activity; GO:0016887 (0.25) ! ATPase activity; GO:0003774 (0.23) ! motor activity; GO:0003777 (0.21) ! microtubule motor activity; GO:0008092 (0.15) ! cytoskeletal protein binding; GO:1901363 (0.12) ! heterocyclic compound binding; GO:0097159 (0.12) ! organic cyclic compound binding; GO:0019899 (0.11) ! enzyme binding; GO:0016740 (0.11) ! transferase activity; GO:0003676 (0.11) ! nucleic acid binding; GO:0015631 (0.08) ! tubulin binding; GO:0005198 (0.08) ! structural molecule activity; GO:0016301 (0.07) ! kinase activity; GO:0008574 (0.07) ! ATP-dependent microtubule motor activity, plus-end-directed; GO:0044877 (0.06) ! macromolecular complex binding; GO:0008017 (0.06) ! microtubule binding; GO:0003779 (0.06) ! actin binding; GO:0003723 (0.06) ! RNA binding; GO:0044822 (0.05) ! poly(A) RNA binding; GO:0042802 (0.05) ! identical protein binding; GO:0032403 (0.05) ! protein complex binding; GO:0017016 (0.05) ! Ras GTPase binding; GO:0005215 (0.05) ! transporter activity; GO:0004674 (0.05) ! protein serine/threonine kinase activity; GO:0046983 (0.04) ! protein dimerization activity; GO:0019901 (0.04) ! protein kinase binding; GO:0017137 (0.04) ! Rab GTPase binding; GO:0016788 (0.04) ! hydrolase activity, acting on ester bonds; GO:0005102 (0.04) ! receptor binding; GO:0004872 (0.04) ! receptor activity; GO:0004871 (0.04) ! signal transducer activity; GO:0003677 (0.04) ! DNA binding; GO:0097367 (0.03) ! carbohydrate derivative binding; GO:0042803 (0.03) ! protein homodimerization activity; GO:0042623 (0.03) ! ATPase activity, coupled; GO:0030234 (0.03) ! enzyme regulator activity; GO:0005487 (0.03) ! nucleocytoplasmic transporter activity; GO:0005200 (0.03) ! structural constituent of cytoskeleton; GO:0004842 (0.03) ! ubiquitin-protein transferase activity; GO:0004702 (0.03) ! receptor signaling protein serine/threonine kinase activity; GO:0004519 (0.03) ! endonuclease activity; GO:0051880 (0.02) ! G-quadruplex DNA binding; GO:0051015 (0.02) ! actin filament binding; GO:0046872 (0.02) ! metal ion binding; GO:0043130 (0.02) ! ubiquitin binding; GO:0043047 (0.02) ! single-stranded telomeric DNA binding; GO:0036094 (0.02) ! small molecule binding; GO:0019904 (0.02) ! protein domain specific binding; GO:0008408 (0.02) ! 3'-5' exonuclease activity; GO:0005543 (0.02) ! phospholipid binding; GO:0005096 (0.02) ! GTPase activator activity; GO:0004017 (0.02) ! adenylate kinase activity; GO:0004003 (0.02) ! ATP-dependent DNA helicase activity; GO:0003729 (0.02) ! mRNA binding; GO:0003712 (0.02) ! transcription cofactor activity; GO:0003691 (0.02) ! double-stranded telomeric DNA binding; GO:0000146 (0.02) ! microfilament motor activity; GO:0000014 (0.02) ! single-stranded DNA endodeoxyribonuclease activity; GO:0098641 (0.01) ! cadherin binding involved in cell-cell adhesion; GO:0070530 (0.01) ! K63-linked polyubiquitin binding; GO:0070011 (0.01) ! peptidase activity, acting on L-amino acid peptides; GO:0051427 (0.01) ! hormone receptor binding; GO:0048487 (0.01) ! beta-tubulin binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0045502 (0.01) ! dynein binding; GO:0044212 (0.01) ! transcription regulatory region DNA binding; GO:0035091 (0.01) ! phosphatidylinositol binding; GO:0032947 (0.01) ! protein complex scaffold; GO:0030898 (0.01) ! actin-dependent ATPase activity; GO:0030674 (0.01) ! protein binding, bridging; GO:0030374 (0.01) ! ligand-dependent nuclear receptor transcription coactivator activity; GO:0022857 (0.01) ! transmembrane transporter activity; GO:0019894 (0.01) ! kinesin binding; GO:0017056 (0.01) ! structural constituent of nuclear pore; GO:0017022 (0.01) ! myosin binding; GO:0008565 (0.01) ! protein transporter activity; GO:0008307 (0.01) ! structural constituent of muscle; GO:0008139 (0.01) ! nuclear localization sequence binding; GO:0008134 (0.01) ! transcription factor binding; GO:0008022 (0.01) ! protein C-terminus binding; GO:0005544 (0.01) ! calcium-dependent phospholipid binding; GO:0005540 (0.01) ! hyaluronic acid binding; GO:0005524 (0.01) ! ATP binding; GO:0005522 (0.01) ! profilin binding; GO:0005516 (0.01) ! calmodulin binding; GO:0005509 (0.01) ! calcium ion binding; GO:0005201 (0.01) ! extracellular matrix structural constituent; GO:0005125 (0.01) ! cytokine activity; GO:0004930 (0.01) ! G-protein coupled receptor activity; GO:0004526 (0.01) ! ribonuclease P activity; GO:0003700 (0.01) ! transcription factor activity, sequence-specific DNA binding; GO:0003682 (0.01) ! chromatin binding; GO:0001664 (0.01) ! G-protein coupled receptor binding GO:0009987 (0.79) ! cellular process; GO:0044699 (0.64) ! single-organism process; GO:0044763 (0.57) ! single-organism cellular process; GO:0016043 (0.43) ! cellular component organization; GO:0065007 (0.36) ! biological regulation; GO:0050789 (0.33) ! regulation of biological process; GO:0050794 (0.31) ! regulation of cellular process; GO:0006996 (0.31) ! organelle organization; GO:0007017 (0.30) ! microtubule-based process; GO:0051179 (0.29) ! localization; GO:0006928 (0.29) ! movement of cell or subcellular component; GO:0032502 (0.28) ! developmental process; GO:0044767 (0.27) ! single-organism developmental process; GO:0051234 (0.26) ! establishment of localization; GO:0051641 (0.22) ! cellular localization; GO:0007018 (0.22) ! microtubule-based movement; GO:0006810 (0.21) ! transport; GO:1902589 (0.20) ! single-organism organelle organization; GO:0051649 (0.20) ! establishment of localization in cell; GO:0048856 (0.17) ! anatomical structure development; GO:0071704 (0.16) ! organic substance metabolic process; GO:0022607 (0.16) ! cellular component assembly; GO:0022402 (0.16) ! cell cycle process; GO:0048518 (0.15) ! positive regulation of biological process; GO:0044238 (0.15) ! primary metabolic process; GO:0044237 (0.15) ! cellular metabolic process; GO:0043170 (0.15) ! macromolecule metabolic process; GO:0007010 (0.15) ! cytoskeleton organization; GO:0046907 (0.14) ! intracellular transport; GO:0044260 (0.14) ! cellular macromolecule metabolic process; GO:0051128 (0.13) ! regulation of cellular component organization; GO:0048869 (0.13) ! cellular developmental process; GO:0048522 (0.13) ! positive regulation of cellular process; GO:0009653 (0.13) ! anatomical structure morphogenesis; GO:0008104 (0.12) ! protein localization; GO:0032501 (0.11) ! multicellular organismal process; GO:1903047 (0.10) ! mitotic cell cycle process; GO:1902578 (0.10) ! single-organism localization; GO:0050896 (0.10) ! response to stimulus; GO:0048519 (0.10) ! negative regulation of biological process; GO:0019222 (0.10) ! regulation of metabolic process; GO:0000226 (0.10) ! microtubule cytoskeleton organization; GO:0080090 (0.09) ! regulation of primary metabolic process; GO:0070925 (0.09) ! organelle assembly; GO:0065008 (0.09) ! regulation of biological quality; GO:0060255 (0.09) ! regulation of macromolecule metabolic process; GO:0051640 (0.09) ! organelle localization; GO:0048646 (0.09) ! anatomical structure formation involved in morphogenesis; GO:0048523 (0.09) ! negative regulation of cellular process; GO:0034641 (0.09) ! cellular nitrogen compound metabolic process; GO:0033043 (0.09) ! regulation of organelle organization; GO:0031323 (0.09) ! regulation of cellular metabolic process; GO:0030030 (0.09) ! cell projection organization; GO:0022414 (0.09) ! reproductive process; GO:1902580 (0.08) ! single-organism cellular localization; GO:1901360 (0.08) ! organic cyclic compound metabolic process; GO:0051656 (0.08) ! establishment of organelle localization; GO:0048513 (0.08) ! animal organ development; GO:0044765 (0.08) ! single-organism transport; GO:0044707 (0.08) ! single-multicellular organism process; GO:0040011 (0.08) ! locomotion; GO:0019538 (0.08) ! protein metabolic process; GO:0016192 (0.08) ! vesicle-mediated transport; GO:0090304 (0.07) ! nucleic acid metabolic process; GO:0050793 (0.07) ! regulation of developmental process; GO:0048870 (0.07) ! cell motility; GO:0048583 (0.07) ! regulation of response to stimulus; GO:0044267 (0.07) ! cellular protein metabolic process; GO:0032879 (0.07) ! regulation of localization; GO:0030705 (0.07) ! cytoskeleton-dependent intracellular transport; GO:0015031 (0.07) ! protein transport; GO:0010927 (0.07) ! cellular component assembly involved in morphogenesis; GO:0007165 (0.07) ! signal transduction; GO:0051726 (0.06) ! regulation of cell cycle; GO:0051239 (0.06) ! regulation of multicellular organismal process; GO:0043933 (0.06) ! macromolecular complex subunit organization; GO:0023051 (0.06) ! regulation of signaling; GO:0010646 (0.06) ! regulation of cell communication; GO:0006950 (0.06) ! response to stress; GO:0006886 (0.06) ! intracellular protein transport; GO:2000112 (0.05) ! regulation of cellular macromolecule biosynthetic process; GO:2000026 (0.05) ! regulation of multicellular organismal development; GO:1902582 (0.05) ! single-organism intracellular transport; GO:0065009 (0.05) ! regulation of molecular function; GO:0065003 (0.05) ! macromolecular complex assembly; GO:0051716 (0.05) ! cellular response to stimulus; GO:0051049 (0.05) ! regulation of transport; GO:0048729 (0.05) ! tissue morphogenesis; GO:0044702 (0.05) ! single organism reproductive process; GO:0034613 (0.05) ! cellular protein localization; GO:0032989 (0.05) ! cellular component morphogenesis; GO:0032268 (0.05) ! regulation of cellular protein metabolic process; GO:0031325 (0.05) ! positive regulation of cellular metabolic process; GO:0030154 (0.05) ! cell differentiation; GO:0030031 (0.05) ! cell projection assembly; GO:0030029 (0.05) ! actin filament-based process; GO:0019219 (0.05) ! regulation of nucleobase-containing compound metabolic process; GO:0016477 (0.05) ! cell migration; GO:0010604 (0.05) ! positive regulation of macromolecule metabolic process; GO:0010564 (0.05) ! regulation of cell cycle process; GO:0010468 (0.05) ! regulation of gene expression; GO:0009966 (0.05) ! regulation of signal transduction; GO:0007155 (0.05) ! cell adhesion; GO:0006464 (0.05) ! cellular protein modification process; GO:1903046 (0.04) ! meiotic cell cycle process; GO:0051493 (0.04) ! regulation of cytoskeleton organization; GO:0051276 (0.04) ! chromosome organization; GO:0051130 (0.04) ! positive regulation of cellular component organization; GO:0051129 (0.04) ! negative regulation of cellular component organization; GO:0050790 (0.04) ! regulation of catalytic activity; GO:0048468 (0.04) ! cell development; GO:0048193 (0.04) ! Golgi vesicle transport; GO:0045595 (0.04) ! regulation of cell differentiation; GO:0044782 (0.04) ! cilium organization; GO:0044271 (0.04) ! cellular nitrogen compound biosynthetic process; GO:0044087 (0.04) ! regulation of cellular component biogenesis; GO:0034645 (0.04) ! cellular macromolecule biosynthetic process; GO:0034622 (0.04) ! cellular macromolecular complex assembly; GO:0033554 (0.04) ! cellular response to stress; GO:0031399 (0.04) ! regulation of protein modification process; GO:0030036 (0.04) ! actin cytoskeleton organization; GO:0022603 (0.04) ! regulation of anatomical structure morphogenesis; GO:0007163 (0.04) ! establishment or maintenance of cell polarity; GO:0006461 (0.04) ! protein complex assembly; GO:0006355 (0.04) ! regulation of transcription, DNA-templated; GO:0006259 (0.04) ! DNA metabolic process; GO:0003008 (0.04) ! system process; GO:0002009 (0.04) ! morphogenesis of an epithelium; GO:1902531 (0.03) ! regulation of intracellular signal transduction; GO:0090305 (0.03) ! nucleic acid phosphodiester bond hydrolysis; GO:0061343 (0.03) ! cell adhesion involved in heart morphogenesis; GO:0061024 (0.03) ! membrane organization; GO:0051983 (0.03) ! regulation of chromosome segregation; GO:0051297 (0.03) ! centrosome organization; GO:0051294 (0.03) ! establishment of spindle orientation; GO:0051240 (0.03) ! positive regulation of multicellular organismal process; GO:0051094 (0.03) ! positive regulation of developmental process; GO:0050767 (0.03) ! regulation of neurogenesis; GO:0048858 (0.03) ! cell projection morphogenesis; GO:0048585 (0.03) ! negative regulation of response to stimulus; GO:0048584 (0.03) ! positive regulation of response to stimulus; GO:0043623 (0.03) ! cellular protein complex assembly; GO:0043085 (0.03) ! positive regulation of catalytic activity; GO:0042981 (0.03) ! regulation of apoptotic process; GO:0042384 (0.03) ! cilium assembly; GO:0042221 (0.03) ! response to chemical; GO:0040007 (0.03) ! growth; GO:0035556 (0.03) ! intracellular signal transduction; GO:0035088 (0.03) ! establishment or maintenance of apical/basal cell polarity; GO:0033365 (0.03) ! protein localization to organelle; GO:0033044 (0.03) ! regulation of chromosome organization; GO:0031401 (0.03) ! positive regulation of protein modification process; GO:0031344 (0.03) ! regulation of cell projection organization; GO:0031324 (0.03) ! negative regulation of cellular metabolic process; GO:0022604 (0.03) ! regulation of cell morphogenesis; GO:0016070 (0.03) ! RNA metabolic process; GO:0010970 (0.03) ! establishment of localization by movement along microtubule; GO:0010639 (0.03) ! negative regulation of organelle organization; GO:0010605 (0.03) ! negative regulation of macromolecule metabolic process; GO:0009888 (0.03) ! tissue development; GO:0009605 (0.03) ! response to external stimulus; GO:0007508 (0.03) ! larval heart development; GO:0007346 (0.03) ! regulation of mitotic cell cycle; GO:0007131 (0.03) ! reciprocal meiotic recombination; GO:0007059 (0.03) ! chromosome segregation; GO:0006974 (0.03) ! cellular response to DNA damage stimulus; GO:0006913 (0.03) ! nucleocytoplasmic transport; GO:0006468 (0.03) ! protein phosphorylation; GO:0003006 (0.03) ! developmental process involved in reproduction; GO:0001932 (0.03) ! regulation of protein phosphorylation; GO:2000113 (0.02) ! negative regulation of cellular macromolecule biosynthetic process; GO:0098840 (0.02) ! protein transport along microtubule; GO:0098534 (0.02) ! centriole assembly; GO:0090501 (0.02) ! RNA phosphodiester bond hydrolysis; GO:0090066 (0.02) ! regulation of anatomical structure size; GO:0080134 (0.02) ! regulation of response to stress; GO:0072594 (0.02) ! establishment of protein localization to organelle; GO:0071103 (0.02) ! DNA conformation change; GO:0070507 (0.02) ! regulation of microtubule cytoskeleton organization; GO:0070192 (0.02) ! chromosome organization involved in meiotic cell cycle; GO:0061640 (0.02) ! cytoskeleton-dependent cytokinesis; GO:0060627 (0.02) ! regulation of vesicle-mediated transport; GO:0060341 (0.02) ! regulation of cellular localization; GO:0060285 (0.02) ! cilium-dependent cell motility; GO:0051704 (0.02) ! multi-organism process; GO:0051345 (0.02) ! positive regulation of hydrolase activity; GO:0051270 (0.02) ! regulation of cellular component movement; GO:0051253 (0.02) ! negative regulation of RNA metabolic process; GO:0051225 (0.02) ! spindle assembly; GO:0051050 (0.02) ! positive regulation of transport; GO:0050769 (0.02) ! positive regulation of neurogenesis; GO:0050000 (0.02) ! chromosome localization; GO:0048812 (0.02) ! neuron projection morphogenesis; GO:0048731 (0.02) ! system development; GO:0048638 (0.02) ! regulation of developmental growth; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0048589 (0.02) ! developmental growth; GO:0045893 (0.02) ! positive regulation of transcription, DNA-templated; GO:0044802 (0.02) ! single-organism membrane organization; GO:0044710 (0.02) ! single-organism metabolic process; GO:0044708 (0.02) ! single-organism behavior; GO:0044089 (0.02) ! positive regulation of cellular component biogenesis; GO:0043207 (0.02) ! response to external biotic stimulus; GO:0043087 (0.02) ! regulation of GTPase activity; GO:0043065 (0.02) ! positive regulation of apoptotic process; GO:0042127 (0.02) ! regulation of cell proliferation; GO:0042073 (0.02) ! intraciliary transport; GO:0040012 (0.02) ! regulation of locomotion; GO:0035239 (0.02) ! tube morphogenesis; GO:0034654 (0.02) ! nucleobase-containing compound biosynthetic process; GO:0032956 (0.02) ! regulation of actin cytoskeleton organization; GO:0032880 (0.02) ! regulation of protein localization; GO:0031346 (0.02) ! positive regulation of cell projection organization; GO:0031032 (0.02) ! actomyosin structure organization; GO:0030198 (0.02) ! extracellular matrix organization; GO:0030048 (0.02) ! actin filament-based movement; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0010975 (0.02) ! regulation of neuron projection development; GO:0010769 (0.02) ! regulation of cell morphogenesis involved in differentiation; GO:0010638 (0.02) ! positive regulation of organelle organization; GO:0010629 (0.02) ! negative regulation of gene expression; GO:0010033 (0.02) ! response to organic substance; GO:0009968 (0.02) ! negative regulation of signal transduction; GO:0009967 (0.02) ! positive regulation of signal transduction; GO:0009904 (0.02) ! chloroplast accumulation movement; GO:0009903 (0.02) ! chloroplast avoidance movement; GO:0009886 (0.02) ! post-embryonic morphogenesis; GO:0009719 (0.02) ! response to endogenous stimulus; GO:0009628 (0.02) ! response to abiotic stimulus; GO:0009056 (0.02) ! catabolic process; GO:0007600 (0.02) ! sensory perception; GO:0007411 (0.02) ! axon guidance; GO:0007389 (0.02) ! pattern specification process; GO:0007275 (0.02) ! multicellular organism development; GO:0007267 (0.02) ! cell-cell signaling; GO:0007166 (0.02) ! cell surface receptor signaling pathway; GO:0007094 (0.02) ! mitotic spindle assembly checkpoint; GO:0007052 (0.02) ! mitotic spindle organization; GO:0007030 (0.02) ! Golgi organization; GO:0007020 (0.02) ! microtubule nucleation; GO:0007015 (0.02) ! actin filament organization; GO:0006936 (0.02) ! muscle contraction; GO:0006897 (0.02) ! endocytosis; GO:0006412 (0.02) ! translation; GO:0006357 (0.02) ! regulation of transcription from RNA polymerase II promoter; GO:0003341 (0.02) ! cilium movement; GO:0002682 (0.02) ! regulation of immune system process; GO:0002376 (0.02) ! immune system process; GO:0001934 (0.02) ! positive regulation of protein phosphorylation; GO:0001578 (0.02) ! microtubule bundle formation; GO:0000904 (0.02) ! cell morphogenesis involved in differentiation; GO:0000724 (0.02) ! double-strand break repair via homologous recombination; GO:0000722 (0.02) ! telomere maintenance via recombination; GO:0000132 (0.02) ! establishment of mitotic spindle orientation; GO:2001252 (0.01) ! positive regulation of chromosome organization; GO:1990778 (0.01) ! protein localization to cell periphery; GO:1903530 (0.01) ! regulation of secretion by cell; GO:1903391 (0.01) ! regulation of adherens junction organization; GO:1903008 (0.01) ! organelle disassembly; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1902017 (0.01) ! regulation of cilium assembly; GO:1901888 (0.01) ! regulation of cell junction assembly; GO:1901701 (0.01) ! cellular response to oxygen-containing compound; GO:1901135 (0.01) ! carbohydrate derivative metabolic process; GO:0098789 (0.01) ! pre-mRNA cleavage required for polyadenylation; GO:0098535 (0.01) ! de novo centriole assembly; GO:0090630 (0.01) ! activation of GTPase activity; GO:0090502 (0.01) ! RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0090316 (0.01) ! positive regulation of intracellular protein transport; GO:0090307 (0.01) ! mitotic spindle assembly; GO:0090161 (0.01) ! Golgi ribbon formation; GO:0090068 (0.01) ! positive regulation of cell cycle process; GO:0090002 (0.01) ! establishment of protein localization to plasma membrane; GO:0072698 (0.01) ! protein localization to microtubule cytoskeleton; GO:0072657 (0.01) ! protein localization to membrane; GO:0071900 (0.01) ! regulation of protein serine/threonine kinase activity; GO:0071417 (0.01) ! cellular response to organonitrogen compound; GO:0070252 (0.01) ! actin-mediated cell contraction; GO:0061025 (0.01) ! membrane fusion; GO:0060429 (0.01) ! epithelium development; GO:0060287 (0.01) ! epithelial cilium movement involved in determination of left/right asymmetry; GO:0060271 (0.01) ! cilium morphogenesis; GO:0055059 (0.01) ! asymmetric neuroblast division; GO:0052553 (0.01) ! modulation by symbiont of host immune response; GO:0051781 (0.01) ! positive regulation of cell division; GO:0051646 (0.01) ! mitochondrion localization; GO:0051642 (0.01) ! centrosome localization; GO:0051495 (0.01) ! positive regulation of cytoskeleton organization; GO:0051492 (0.01) ! regulation of stress fiber assembly; GO:0051491 (0.01) ! positive regulation of filopodium assembly; GO:0051315 (0.01) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051241 (0.01) ! negative regulation of multicellular organismal process; GO:0051093 (0.01) ! negative regulation of developmental process; GO:0051052 (0.01) ! regulation of DNA metabolic process; GO:0050890 (0.01) ! cognition; GO:0050808 (0.01) ! synapse organization; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0050778 (0.01) ! positive regulation of immune response; GO:0048813 (0.01) ! dendrite morphogenesis; GO:0048747 (0.01) ! muscle fiber development; GO:0048568 (0.01) ! embryonic organ development; GO:0048489 (0.01) ! synaptic vesicle transport; GO:0048211 (0.01) ! Golgi vesicle docking; GO:0047496 (0.01) ! vesicle transport along microtubule; GO:0046777 (0.01) ! protein autophosphorylation; GO:0046331 (0.01) ! lateral inhibition; GO:0046330 (0.01) ! positive regulation of JNK cascade; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045931 (0.01) ! positive regulation of mitotic cell cycle; GO:0045862 (0.01) ! positive regulation of proteolysis; GO:0045785 (0.01) ! positive regulation of cell adhesion; GO:0045773 (0.01) ! positive regulation of axon extension; GO:0045596 (0.01) ! negative regulation of cell differentiation; GO:0045216 (0.01) ! cell-cell junction organization; GO:0045214 (0.01) ! sarcomere organization; GO:0045109 (0.01) ! intermediate filament organization; GO:0045087 (0.01) ! innate immune response; GO:0045056 (0.01) ! transcytosis; GO:0044281 (0.01) ! small molecule metabolic process; GO:0044057 (0.01) ! regulation of system process; GO:0043270 (0.01) ! positive regulation of ion transport; GO:0043161 (0.01) ! proteasome-mediated ubiquitin-dependent protein catabolic process; GO:0043122 (0.01) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043086 (0.01) ! negative regulation of catalytic activity; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043009 (0.01) ! chordate embryonic development; GO:0042391 (0.01) ! regulation of membrane potential; GO:0042330 (0.01) ! taxis; GO:0042246 (0.01) ! tissue regeneration; GO:0036159 (0.01) ! inner dynein arm assembly; GO:0035295 (0.01) ! tube development; GO:0035149 (0.01) ! lumen formation, open tracheal system; GO:0035147 (0.01) ! branch fusion, open tracheal system; GO:0035082 (0.01) ! axoneme assembly; GO:0034454 (0.01) ! microtubule anchoring at centrosome; GO:0034329 (0.01) ! cell junction assembly; GO:0033993 (0.01) ! response to lipid; GO:0032844 (0.01) ! regulation of homeostatic process; GO:0032774 (0.01) ! RNA biosynthetic process; GO:0032508 (0.01) ! DNA duplex unwinding; GO:0032465 (0.01) ! regulation of cytokinesis; GO:0032412 (0.01) ! regulation of ion transmembrane transporter activity; GO:0032271 (0.01) ! regulation of protein polymerization; GO:0032147 (0.01) ! activation of protein kinase activity; GO:0031589 (0.01) ! cell-substrate adhesion; GO:0031532 (0.01) ! actin cytoskeleton reorganization; GO:0031338 (0.01) ! regulation of vesicle fusion; GO:0031175 (0.01) ! neuron projection development; GO:0031034 (0.01) ! myosin filament assembly; GO:0030866 (0.01) ! cortical actin cytoskeleton organization; GO:0030855 (0.01) ! epithelial cell differentiation; GO:0030716 (0.01) ! oocyte fate determination; GO:0030707 (0.01) ! ovarian follicle cell development; GO:0030335 (0.01) ! positive regulation of cell migration; GO:0030239 (0.01) ! myofibril assembly; GO:0022618 (0.01) ! ribonucleoprotein complex assembly; GO:0022404 (0.01) ! molting cycle process; GO:0022008 (0.01) ! neurogenesis; GO:0019637 (0.01) ! organophosphate metabolic process; GO:0019233 (0.01) ! sensory perception of pain; GO:0018193 (0.01) ! peptidyl-amino acid modification; GO:0016570 (0.01) ! histone modification; GO:0016482 (0.01) ! cytosolic transport; GO:0016337 (0.01) ! single organismal cell-cell adhesion; GO:0016319 (0.01) ! mushroom body development; GO:0016233 (0.01) ! telomere capping; GO:0016204 (0.01) ! determination of muscle attachment site; GO:0016203 (0.01) ! muscle attachment; GO:0016199 (0.01) ! axon midline choice point recognition; GO:0016197 (0.01) ! endosomal transport; GO:0016050 (0.01) ! vesicle organization; GO:0016032 (0.01) ! viral process; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0010959 (0.01) ! regulation of metal ion transport; GO:0010824 (0.01) ! regulation of centrosome duplication; GO:0009887 (0.01) ! organ morphogenesis; GO:0009798 (0.01) ! axis specification; GO:0009725 (0.01) ! response to hormone; GO:0009611 (0.01) ! response to wounding; GO:0009416 (0.01) ! response to light stimulus; GO:0009266 (0.01) ! response to temperature stimulus; GO:0008360 (0.01) ! regulation of cell shape; GO:0008344 (0.01) ! adult locomotory behavior; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008088 (0.01) ! axo-dendritic transport; GO:0008064 (0.01) ! regulation of actin polymerization or depolymerization; GO:0007605 (0.01) ! sensory perception of sound; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007517 (0.01) ! muscle organ development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007475 (0.01) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.01) ! open tracheal system development; GO:0007420 (0.01) ! brain development; GO:0007409 (0.01) ! axonogenesis; GO:0007368 (0.01) ! determination of left/right symmetry; GO:0007281 (0.01) ! germ cell development; GO:0007276 (0.01) ! gamete generation; GO:0007269 (0.01) ! neurotransmitter secretion; GO:0007268 (0.01) ! chemical synaptic transmission; GO:0007265 (0.01) ! Ras protein signal transduction; GO:0007169 (0.01) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0007100 (0.01) ! mitotic centrosome separation; GO:0007099 (0.01) ! centriole replication; GO:0007097 (0.01) ! nuclear migration; GO:0007080 (0.01) ! mitotic metaphase plate congression; GO:0007067 (0.01) ! mitotic nuclear division; GO:0007062 (0.01) ! sister chromatid cohesion; GO:0007026 (0.01) ! negative regulation of microtubule depolymerization; GO:0007009 (0.01) ! plasma membrane organization; GO:0007005 (0.01) ! mitochondrion organization; GO:0007004 (0.01) ! telomere maintenance via telomerase; GO:0006997 (0.01) ! nucleus organization; GO:0006941 (0.01) ! striated muscle contraction; GO:0006914 (0.01) ! autophagy; GO:0006892 (0.01) ! post-Golgi vesicle-mediated transport; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006887 (0.01) ! exocytosis; GO:0006606 (0.01) ! protein import into nucleus; GO:0006605 (0.01) ! protein targeting; GO:0006405 (0.01) ! RNA export from nucleus; GO:0006396 (0.01) ! RNA processing; GO:0003198 (0.01) ! epithelial to mesenchymal transition involved in endocardial cushion formation; GO:0003013 (0.01) ! circulatory system process; GO:0002694 (0.01) ! regulation of leukocyte activation; GO:0001952 (0.01) ! regulation of cell-matrix adhesion; GO:0001947 (0.01) ! heart looping; GO:0001933 (0.01) ! negative regulation of protein phosphorylation; GO:0001822 (0.01) ! kidney development; GO:0001667 (0.01) ! ameboidal-type cell migration; GO:0001654 (0.01) ! eye development; GO:0000301 (0.01) ! retrograde transport, vesicle recycling within Golgi; GO:0000281 (0.01) ! mitotic cytokinesis; GO:0000278 (0.01) ! mitotic cell cycle; GO:0000209 (0.01) ! protein polyubiquitination; GO:0000122 (0.01) ! negative regulation of transcription from RNA polymerase II promoter; GO:0000086 (0.01) ! G2/M transition of mitotic cell cycle; GO:0000077 (0.01) ! DNA damage checkpoint; GO:0000070 (0.01) ! mitotic sister chromatid segregation; GO:0000045 (0.01) ! autophagosome assembly GO:0044464 (0.92) ! cell part; GO:0044424 (0.87) ! intracellular part; GO:0044422 (0.61) ! organelle part; GO:0044446 (0.59) ! intracellular organelle part; GO:0043226 (0.45) ! organelle; GO:0043229 (0.42) ! intracellular organelle; GO:0044430 (0.40) ! cytoskeletal part; GO:0032991 (0.39) ! macromolecular complex; GO:0044444 (0.36) ! cytoplasmic part; GO:0043234 (0.36) ! protein complex; GO:0043227 (0.26) ! membrane-bounded organelle; GO:0043232 (0.24) ! intracellular non-membrane-bounded organelle; GO:0043231 (0.23) ! intracellular membrane-bounded organelle; GO:0005737 (0.20) ! cytoplasm; GO:0044428 (0.17) ! nuclear part; GO:0005875 (0.17) ! microtubule associated complex; GO:0016020 (0.16) ! membrane; GO:0005871 (0.16) ! kinesin complex; GO:0044421 (0.12) ! extracellular region part; GO:0005634 (0.11) ! nucleus; GO:0005815 (0.10) ! microtubule organizing center; GO:0044427 (0.08) ! chromosomal part; GO:0044425 (0.08) ! membrane part; GO:0031982 (0.08) ! vesicle; GO:0005813 (0.08) ! centrosome; GO:0044463 (0.07) ! cell projection part; GO:0031988 (0.07) ! membrane-bounded vesicle; GO:0005829 (0.07) ! cytosol; GO:0099513 (0.06) ! polymeric cytoskeletal fiber; GO:0042995 (0.06) ! cell projection; GO:0005856 (0.06) ! cytoskeleton; GO:0097458 (0.05) ! neuron part; GO:0070062 (0.05) ! extracellular exosome; GO:0044459 (0.05) ! plasma membrane part; GO:0044441 (0.05) ! ciliary part; GO:0031090 (0.05) ! organelle membrane; GO:0030054 (0.05) ! cell junction; GO:0005886 (0.05) ! plasma membrane; GO:0005794 (0.05) ! Golgi apparatus; GO:0005654 (0.05) ! nucleoplasm; GO:0098588 (0.04) ! bounding membrane of organelle; GO:0044454 (0.04) ! nuclear chromosome part; GO:0044450 (0.04) ! microtubule organizing center part; GO:0044448 (0.04) ! cell cortex part; GO:0031012 (0.04) ! extracellular matrix; GO:1902494 (0.03) ! catalytic complex; GO:0098805 (0.03) ! whole membrane; GO:0044449 (0.03) ! contractile fiber part; GO:0044431 (0.03) ! Golgi apparatus part; GO:0030529 (0.03) ! intracellular ribonucleoprotein complex; GO:0016023 (0.03) ! cytoplasmic, membrane-bounded vesicle; GO:0016021 (0.03) ! integral component of membrane; GO:0005938 (0.03) ! cell cortex; GO:0005929 (0.03) ! cilium; GO:0005912 (0.03) ! adherens junction; GO:0005874 (0.03) ! microtubule; GO:0005814 (0.03) ! centriole; GO:0005615 (0.03) ! extracellular space; GO:0005578 (0.03) ! proteinaceous extracellular matrix; GO:0000922 (0.03) ! spindle pole; GO:0000776 (0.03) ! kinetochore; GO:1990752 (0.02) ! microtubule end; GO:1990234 (0.02) ! transferase complex; GO:0098791 (0.02) ! Golgi subcompartment; GO:0098687 (0.02) ! chromosomal region; GO:0098590 (0.02) ! plasma membrane region; GO:0048471 (0.02) ! perinuclear region of cytoplasm; GO:0045202 (0.02) ! synapse; GO:0044456 (0.02) ! synapse part; GO:0044451 (0.02) ! nucleoplasm part; GO:0044432 (0.02) ! endoplasmic reticulum part; GO:0044420 (0.02) ! extracellular matrix component; GO:0043005 (0.02) ! neuron projection; GO:0031967 (0.02) ! organelle envelope; GO:0030496 (0.02) ! midbody; GO:0016459 (0.02) ! myosin complex; GO:0005930 (0.02) ! axoneme; GO:0005924 (0.02) ! cell-substrate adherens junction; GO:0005911 (0.02) ! cell-cell junction; GO:0005882 (0.02) ! intermediate filament; GO:0005876 (0.02) ! spindle microtubule; GO:0005819 (0.02) ! spindle; GO:0005768 (0.02) ! endosome; GO:0005739 (0.02) ! mitochondrion; GO:0005643 (0.02) ! nuclear pore; GO:0005622 (0.02) ! intracellular; GO:0005576 (0.02) ! extracellular region; GO:0000793 (0.02) ! condensed chromosome; GO:0000790 (0.02) ! nuclear chromatin; GO:1990316 (0.01) ! ATG1/ULK1 kinase complex; GO:0098802 (0.01) ! plasma membrane receptor complex; GO:0098589 (0.01) ! membrane region; GO:0097539 (0.01) ! ciliary transition fiber; GO:0097431 (0.01) ! mitotic spindle pole; GO:0072686 (0.01) ! mitotic spindle; GO:0072372 (0.01) ! primary cilium; GO:0070938 (0.01) ! contractile ring; GO:0051233 (0.01) ! spindle midzone; GO:0048788 (0.01) ! cytoskeleton of presynaptic active zone; GO:0048786 (0.01) ! presynaptic active zone; GO:0045179 (0.01) ! apical cortex; GO:0045177 (0.01) ! apical part of cell; GO:0045169 (0.01) ! fusome; GO:0045111 (0.01) ! intermediate filament cytoskeleton; GO:0045095 (0.01) ! keratin filament; GO:0044613 (0.01) ! nuclear pore central transport channel; GO:0044445 (0.01) ! cytosolic part; GO:0044295 (0.01) ! axonal growth cone; GO:0043292 (0.01) ! contractile fiber; GO:0043025 (0.01) ! neuronal cell body; GO:0042734 (0.01) ! presynaptic membrane; GO:0042641 (0.01) ! actomyosin; GO:0036064 (0.01) ! ciliary basal body; GO:0035861 (0.01) ! site of double-strand break; GO:0035371 (0.01) ! microtubule plus-end; GO:0034451 (0.01) ! centriolar satellite; GO:0034045 (0.01) ! pre-autophagosomal structure membrane; GO:0032432 (0.01) ! actin filament bundle; GO:0032154 (0.01) ! cleavage furrow; GO:0031985 (0.01) ! Golgi cisterna; GO:0031968 (0.01) ! organelle outer membrane; GO:0031965 (0.01) ! nuclear membrane; GO:0031262 (0.01) ! Ndc80 complex; GO:0031253 (0.01) ! cell projection membrane; GO:0031252 (0.01) ! cell leading edge; GO:0030992 (0.01) ! intraciliary transport particle B; GO:0030870 (0.01) ! Mre11 complex; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030176 (0.01) ! integral component of endoplasmic reticulum membrane; GO:0030175 (0.01) ! filopodium; GO:0030141 (0.01) ! secretory granule; GO:0030133 (0.01) ! transport vesicle; GO:0030027 (0.01) ! lamellipodium; GO:0030018 (0.01) ! Z disc; GO:0030017 (0.01) ! sarcomere; GO:0019898 (0.01) ! extrinsic component of membrane; GO:0016604 (0.01) ! nuclear body; GO:0016363 (0.01) ! nuclear matrix; GO:0016324 (0.01) ! apical plasma membrane; GO:0015630 (0.01) ! microtubule cytoskeleton; GO:0015629 (0.01) ! actin cytoskeleton; GO:0014069 (0.01) ! postsynaptic density; GO:0012507 (0.01) ! ER to Golgi transport vesicle membrane; GO:0012505 (0.01) ! endomembrane system; GO:0009986 (0.01) ! cell surface; GO:0008091 (0.01) ! spectrin; GO:0005927 (0.01) ! muscle tendon junction; GO:0005925 (0.01) ! focal adhesion; GO:0005913 (0.01) ! cell-cell adherens junction; GO:0005887 (0.01) ! integral component of plasma membrane; GO:0005884 (0.01) ! actin filament; GO:0005859 (0.01) ! muscle myosin complex; GO:0005847 (0.01) ! mRNA cleavage and polyadenylation specificity factor complex; GO:0005840 (0.01) ! ribosome; GO:0005802 (0.01) ! trans-Golgi network; GO:0005801 (0.01) ! cis-Golgi network; GO:0005795 (0.01) ! Golgi stack; GO:0005783 (0.01) ! endoplasmic reticulum; GO:0005774 (0.01) ! vacuolar membrane; GO:0005730 (0.01) ! nucleolus; GO:0005667 (0.01) ! transcription factor complex; GO:0005655 (0.01) ! nucleolar ribonuclease P complex; GO:0005635 (0.01) ! nuclear envelope; GO:0005618 (0.01) ! cell wall; GO:0005604 (0.01) ! basement membrane; GO:0005581 (0.01) ! collagen trimer; GO:0000940 (0.01) ! condensed chromosome outer kinetochore; GO:0000795 (0.01) ! synaptonemal complex; GO:0000794 (0.01) ! condensed nuclear chromosome; GO:0000784 (0.01) ! nuclear chromosome, telomeric region; GO:0000778 (0.01) ! condensed nuclear chromosome kinetochore; GO:0000775 (0.01) ! chromosome, centromeric region; GO:0000242 (0.01) ! pericentriolar material; GO:0000235 (0.01) ! astral microtubule; GO:0000151 (0.01) ! ubiquitin ligase complex; GO:0000139 (0.01) ! Golgi membrane 3 76274049-76307998 (17q25.1) High: testis (cells in seminiferous ducts); Testis: 51.16; Brain - Cerebellum: 13.10; Brain - Cerebellar Hemisphere: 12.40; Thyroid: 12.03; Nerve - Tibial: 5.78; Minor Salivary Gland: 5.09; Cervix - Endocervix: 4.52; Prostate: 4.47; Brain - Cortex: 4.36; Vagina: 4.11; Brain - Frontal Cortex (BA9): 4.02; Cervix - Ectocervix: 3.98; Uterus: 3.77; Brain - Hypothalamus: 3.75; Brain - Nucleus accumbens (basal ganglia): 3.67; Pituitary: 3.63; Fallopian Tube: 3.61; Lung: 3.56; Artery - Aorta: 3.55; Brain - Caudate (basal ganglia): 3.39; Esophagus - Mucosa: 3.38; Brain - Spinal cord (cervical c-1): 3.37; Colon - Sigmoid: 3.07; Artery - Coronary: 3.02; Ovary: 2.95; Brain - Putamen (basal ganglia): 2.84; Brain - Anterior cingulate cortex (BA24): 2.79; Breast - Mammary Tissue: 2.44; Skin - Not Sun Exposed (Suprapubic): 2.44; Brain - Substantia nigra: 2.34; Skin - Sun Exposed (Lower leg): 2.24; Brain - Hippocampus: 2.20; Esophagus - Gastroesophageal Junction: 2.17; Spleen: 2.13; Esophagus - Muscularis: 2.13; Brain - Amygdala: 2.06; Colon - Transverse: 2.03; Bladder: 1.97; Small Intestine - Terminal Ileum: 1.96; Artery - Tibial: 1.95; Cells - Transformed fibroblasts: 1.90; Adipose - Visceral (Omentum): 1.70; Adipose - Subcutaneous: 1.62; Liver: 1.61; Stomach: 1.51; Kidney - Cortex: 1.42; Pancreas: 1.21; Heart - Atrial Appendage: 1.15; Adrenal Gland: 1.04; Muscle - Skeletal: 0.94; Heart - Left Ventricle: 0.84; Whole Blood: 0.58; Cells - EBV-transformed lymphocytes: 0.53; MKDAAEELSFARVLLQRVDELEKLFKDREQFLELVSRKLSLVPGAEEVTMVTWEELEQAITDGWRASQAGSETLMGFSKHGGFTSLTSPEGTLSGDSTKQPSIEQALDSASGLGPDRTASGSGGTAHPSDGVSSREQSKVPSGTGRQQQPRARDEAGVPRLHQSSTFQFKSDSDRHRSREKLTSTQPRRNARPGPVQQDLPLARDQPSSVPASQSQVHLRPDRRGLEPTGMNQPGLVPASTYPHGVVPLSMGQLGVPPPEMDDRELIPFVVDEQRMLPPSVPGRDQQGLELPSTDQHGLVSVSAYQHGMTFPGTDQRSMEPLGMDQRGCVISGMGQQGLVPPGIDQQGLTLPVVDQHGLVLPFTDQHGLVSPGLMPISADQQGFVQPSLEATGFIQPGTEQHDLIQSGRFQRALVQRGAYQPGLVQPGADQRGLVRPGMDQSGLAQPGADQRGLVWPGMDQSGLAQPGRDQHGLIQPGTGQHDLVQSGTGQGVLVQPGVDQPGMVQPGRFQRALVQPGAYQPGLVQPGADQIDVVQPGADQHGLVQSGADQSDLAQPGAVQHGLVQPGVDQRGLAQPRADHQRGLVPPGADQRGLVQPGADQHGLVQPGVDQHGLAQPGEVQRSLVQPGIVQRGLVQPGAVQRGLVQPGAVQRGLVQPGVDQRGLVQPGAVQRGLVQPGAVQHGLVQPGADQRGLVQPGVDQRGLVQPGVDQRGLVQPGMDQRGLIQPGADQPGLVQPGAGQLGMVQPGIGQQGMVQPQADPHGLVQPGAYPLGLVQPGAYLHDLSQSGTYPRGLVQPGMDQYGLRQPGAYQPGLIAPGTKLRGSSTFQADSTGFISVRPYQHGMVPPGREQYGQVSPLLASQGLASPGIDRRSLVPPETYQQGLMHPGTDQHSPIPLSTGLGSTHPDQQHVASPGPGEHDQVYPDAAQHGHAFSLFDSHDSMYPGYRGPGYLSADQHGQEGLDPNRTRASDRHGIPAQKAPGQDVTLFRSPDSVDRVLSEGSEVSSEVLSERRNSLRRMSSSFPTAVETFHLMGELSSLYVGLKESMKDLDEEQAGQTDLEKIQFLLAQMVKRTIPPELQEQLKTVKTLAKEVWQEKAKVERLQRILEGEGNQEAGKELKAGELRLQLGVLRVTVADIEKELAELRESQDRGKAAMENSVSEASLYLQDQLDKLRMIIESMLTSSSTLLSMSMAPHKAHTLAPGQIDPEATCPACSLDVSHQVSTLVRRYEQLQDMVNSLAVSRPSKKAKLQRQDEELLGRVQSAILQVQGDCEKLNITTSNLIEDHRQKQKDIAMLYQGLEKLEKEKANREHLEMEIDVKADKSALATKVSRVQFDATTEQLNHMMQELVAKMSGQEQDWQKMLDRLLTEMDNKLDRLELDPVKQLLEDRWKSLRQQLRERPPLYQADEAAAMRRQLLAHFHCLSCDRPLETPVTGHAIPVTPAGPGLPGHHSIRPYTVFELEQVRQHSRNLKLGSAFPRGDLAQMEQSVGRLRSMHSKMLMNIEKVQIHFGGSTKASSQIIRELLHAQCLGSPCYKRVTDMADYTYSTVPRRCGGSHTLTYPYHRSRPQHLPRGLYPTEEIQIAMKHDEVDILGLDGHIYKGRMDTRLPGILRKDSSGTSKRKSQQPRPHVHRPPSLSSNGQLPSRPQSAQISAGNTSER MXRA7 Matrix-remodeling-associated protein 7 MXRA7_HUMAN (P84157-1) GO:0003676 (0.40) ! nucleic acid binding; GO:0005198 (0.29) ! structural molecule activity; GO:0003824 (0.21) ! catalytic activity; GO:0003700 (0.12) ! transcription factor activity, sequence-specific DNA binding; GO:0003677 (0.12) ! DNA binding; GO:0097157 (0.10) ! pre-mRNA intronic binding; GO:0030623 (0.10) ! U5 snRNA binding; GO:0030620 (0.10) ! U2 snRNA binding; GO:0030619 (0.10) ! U1 snRNA binding; GO:0017070 (0.10) ! U6 snRNA binding; GO:0000386 (0.10) ! second spliceosomal transesterification activity; GO:0005543 (0.09) ! phospholipid binding; GO:0008324 (0.08) ! cation transmembrane transporter activity; GO:0004702 (0.07) ! receptor signaling protein serine/threonine kinase activity; GO:0016787 (0.06) ! hydrolase activity; GO:0042329 (0.05) ! structural constituent of collagen and cuticulin-based cuticle; GO:0017056 (0.05) ! structural constituent of nuclear pore; GO:0005544 (0.05) ! calcium-dependent phospholipid binding; GO:0005522 (0.05) ! profilin binding; GO:0005509 (0.05) ! calcium ion binding; GO:0044325 (0.04) ! ion channel binding; GO:0005384 (0.04) ! manganese ion transmembrane transporter activity; GO:0005381 (0.04) ! iron ion transmembrane transporter activity; GO:0005261 (0.04) ! cation channel activity; GO:0042802 (0.03) ! identical protein binding; GO:0030674 (0.03) ! protein binding, bridging; GO:0003918 (0.03) ! DNA topoisomerase type II (ATP-hydrolyzing) activity; GO:0043236 (0.02) ! laminin binding; GO:0017124 (0.02) ! SH3 domain binding; GO:0005518 (0.02) ! collagen binding; GO:0005178 (0.02) ! integrin binding; GO:0005080 (0.02) ! protein kinase C binding; GO:0004222 (0.02) ! metalloendopeptidase activity GO:0009987 (0.84) ! cellular process; GO:0050896 (0.43) ! response to stimulus; GO:0051716 (0.37) ! cellular response to stimulus; GO:0006950 (0.31) ! response to stress; GO:0044699 (0.30) ! single-organism process; GO:0044238 (0.30) ! primary metabolic process; GO:0043170 (0.30) ! macromolecule metabolic process; GO:0016043 (0.29) ! cellular component organization; GO:0090304 (0.28) ! nucleic acid metabolic process; GO:0044260 (0.28) ! cellular macromolecule metabolic process; GO:0044763 (0.27) ! single-organism cellular process; GO:0016070 (0.25) ! RNA metabolic process; GO:0006979 (0.24) ! response to oxidative stress; GO:0065007 (0.23) ! biological regulation; GO:0071470 (0.22) ! cellular response to osmotic stress; GO:0009650 (0.22) ! UV protection; GO:0050789 (0.20) ! regulation of biological process; GO:0006996 (0.18) ! organelle organization; GO:0006810 (0.18) ! transport; GO:0050794 (0.16) ! regulation of cellular process; GO:0000398 (0.16) ! mRNA splicing, via spliceosome; GO:0032879 (0.15) ! regulation of localization; GO:0022607 (0.15) ! cellular component assembly; GO:0071705 (0.14) ! nitrogen compound transport; GO:0071702 (0.14) ! organic substance transport; GO:0070887 (0.14) ! cellular response to chemical stimulus; GO:0010038 (0.14) ! response to metal ion; GO:0065003 (0.13) ! macromolecular complex assembly; GO:0071248 (0.12) ! cellular response to metal ion; GO:0065008 (0.11) ! regulation of biological quality; GO:0051592 (0.11) ! response to calcium ion; GO:0051049 (0.11) ! regulation of transport; GO:0007010 (0.11) ! cytoskeleton organization; GO:1902589 (0.10) ! single-organism organelle organization; GO:0051028 (0.10) ! mRNA transport; GO:0000389 (0.10) ! mRNA 3'-splice site recognition; GO:0000350 (0.10) ! generation of catalytic spliceosome for second transesterification step; GO:0000244 (0.10) ! spliceosomal tri-snRNP complex assembly; GO:0071277 (0.09) ! cellular response to calcium ion; GO:0032501 (0.09) ! multicellular organismal process; GO:0006366 (0.09) ! transcription from RNA polymerase II promoter; GO:0048856 (0.08) ! anatomical structure development; GO:0006461 (0.08) ! protein complex assembly; GO:1902578 (0.07) ! single-organism localization; GO:0034616 (0.07) ! response to laminar fluid shear stress; GO:0030036 (0.07) ! actin cytoskeleton organization; GO:0006875 (0.07) ! cellular metal ion homeostasis; GO:1903530 (0.06) ! regulation of secretion by cell; GO:0048523 (0.06) ! negative regulation of cellular process; GO:0030335 (0.06) ! positive regulation of cell migration; GO:0007165 (0.06) ! signal transduction; GO:0007160 (0.06) ! cell-matrix adhesion; GO:1990267 (0.05) ! response to transition metal nanoparticle; GO:1903047 (0.05) ! mitotic cell cycle process; GO:1902531 (0.05) ! regulation of intracellular signal transduction; GO:0048739 (0.05) ! cardiac muscle fiber development; GO:0046822 (0.05) ! regulation of nucleocytoplasmic transport; GO:0031505 (0.05) ! fungal-type cell wall organization; GO:0006999 (0.05) ! nuclear pore organization; GO:0001701 (0.05) ! in utero embryonic development; GO:0001570 (0.05) ! vasculogenesis; GO:0000059 (0.05) ! protein import into nucleus, docking; GO:0035418 (0.04) ! protein localization to synapse; GO:0030073 (0.04) ! insulin secretion; GO:0019933 (0.04) ! cAMP-mediated signaling; GO:0017157 (0.04) ! regulation of exocytosis; GO:0016080 (0.04) ! synaptic vesicle targeting; GO:0006939 (0.04) ! smooth muscle contraction; GO:1902236 (0.03) ! negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; GO:0071421 (0.03) ! manganese ion transmembrane transport; GO:0071281 (0.03) ! cellular response to iron ion; GO:0070208 (0.03) ! protein heterotrimerization; GO:0044774 (0.03) ! mitotic DNA integrity checkpoint; GO:0032469 (0.03) ! endoplasmic reticulum calcium ion homeostasis; GO:0030026 (0.03) ! cellular manganese ion homeostasis; GO:0006880 (0.03) ! intracellular sequestering of iron ion; GO:0006312 (0.03) ! mitotic recombination; GO:0006268 (0.03) ! DNA unwinding involved in DNA replication; GO:0006265 (0.03) ! DNA topological change; GO:0001944 (0.03) ! vasculature development; GO:0001935 (0.03) ! endothelial cell proliferation; GO:0000819 (0.03) ! sister chromatid segregation; GO:0000712 (0.03) ! resolution of meiotic recombination intermediates; GO:0071222 (0.02) ! cellular response to lipopolysaccharide; GO:0051549 (0.02) ! positive regulation of keratinocyte migration; GO:0051384 (0.02) ! response to glucocorticoid; GO:0051044 (0.02) ! positive regulation of membrane protein ectodomain proteolysis; GO:0050714 (0.02) ! positive regulation of protein secretion; GO:0042542 (0.02) ! response to hydrogen peroxide; GO:0042117 (0.02) ! monocyte activation; GO:0034612 (0.02) ! response to tumor necrosis factor; GO:0034241 (0.02) ! positive regulation of macrophage fusion; GO:0033630 (0.02) ! positive regulation of cell adhesion mediated by integrin; GO:0033627 (0.02) ! cell adhesion mediated by integrin; GO:0016477 (0.02) ! cell migration; GO:0010042 (0.02) ! response to manganese ion; GO:0007179 (0.02) ! transforming growth factor beta receptor signaling pathway; GO:0007121 (0.02) ! bipolar cellular bud site selection; GO:0007120 (0.02) ! axial cellular bud site selection; GO:0006897 (0.02) ! endocytosis; GO:0006509 (0.02) ! membrane protein ectodomain proteolysis; GO:0000186 (0.02) ! activation of MAPKK activity; GO:0000147 (0.02) ! actin cortical patch assembly GO:0044464 (0.99) ! cell part; GO:0044424 (0.85) ! intracellular part; GO:0043227 (0.71) ! membrane-bounded organelle; GO:0043229 (0.68) ! intracellular organelle; GO:0043231 (0.67) ! intracellular membrane-bounded organelle; GO:0005634 (0.59) ! nucleus; GO:0044446 (0.55) ! intracellular organelle part; GO:0044428 (0.53) ! nuclear part; GO:0032991 (0.45) ! macromolecular complex; GO:0009986 (0.30) ! cell surface; GO:0044444 (0.26) ! cytoplasmic part; GO:0016020 (0.24) ! membrane; GO:0071013 (0.23) ! catalytic step 2 spliceosome; GO:0043234 (0.23) ! protein complex; GO:0005737 (0.23) ! cytoplasm; GO:0005682 (0.23) ! U5 snRNP; GO:0005643 (0.23) ! nuclear pore; GO:0044425 (0.22) ! membrane part; GO:0046540 (0.17) ! U4/U6 x U5 tri-snRNP complex; GO:0071944 (0.14) ! cell periphery; GO:0070062 (0.13) ! extracellular exosome; GO:0005576 (0.13) ! extracellular region; GO:0044459 (0.12) ! plasma membrane part; GO:0005829 (0.11) ! cytosol; GO:0005654 (0.11) ! nucleoplasm; GO:0016323 (0.10) ! basolateral plasma membrane; GO:0005618 (0.10) ! cell wall; GO:0031224 (0.09) ! intrinsic component of membrane; GO:0016021 (0.07) ! integral component of membrane; GO:0005912 (0.07) ! adherens junction; GO:0072380 (0.06) ! TRC complex; GO:0071818 (0.06) ! BAT3 complex; GO:0044611 (0.06) ! nuclear pore inner ring; GO:0042597 (0.06) ! periplasmic space; GO:0042470 (0.06) ! melanosome; GO:0031526 (0.06) ! brush border membrane; GO:0016607 (0.06) ! nuclear speck; GO:0016324 (0.06) ! apical plasma membrane; GO:0016234 (0.06) ! inclusion body; GO:0008180 (0.06) ! COP9 signalosome; GO:0005913 (0.06) ! cell-cell adherens junction; GO:0005739 (0.06) ! mitochondrion; GO:0005622 (0.06) ! intracellular; GO:0044430 (0.05) ! cytoskeletal part; GO:0005783 (0.05) ! endoplasmic reticulum; GO:0031941 (0.04) ! filamentous actin; GO:0030446 (0.04) ! hyphal cell wall; GO:0030018 (0.04) ! Z disc; GO:0016461 (0.04) ! unconventional myosin complex; GO:0045202 (0.03) ! synapse; GO:0014069 (0.03) ! postsynaptic density; GO:0010168 (0.03) ! ER body; GO:0005794 (0.03) ! Golgi apparatus; GO:0030479 (0.02) ! actin cortical patch; GO:0019898 (0.02) ! extrinsic component of membrane; GO:0012505 (0.02) ! endomembrane system; GO:0009330 (0.02) ! DNA topoisomerase complex (ATP-hydrolyzing); GO:0009295 (0.02) ! nucleoid; GO:0031233 (0.01) ! intrinsic component of external side of plasma membrane; GO:0005925 (0.01) ! focal adhesion; GO:0005886 (0.01) ! plasma membrane; GO:0005615 (0.01) ! extracellular space GO:0031012 ! extracellular matrix GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 76672551-76711016 (17q25.1) Artery - Aorta: 150.00; Artery - Tibial: 143.10; Artery - Coronary: 121.90; Colon - Sigmoid: 114.40; Esophagus - Gastroesophageal Junction: 112.00; Esophagus - Muscularis: 106.80; Uterus: 99.08; Fallopian Tube: 81.21; Thyroid: 79.62; Cells - Transformed fibroblasts: 78.86; Bladder: 75.66; Nerve - Tibial: 73.11; Heart - Atrial Appendage: 71.21; Cervix - Endocervix: 67.54; Adipose - Subcutaneous: 65.00; Adrenal Gland: 61.58; Ovary: 60.34; Cervix - Ectocervix: 56.46; Adipose - Visceral (Omentum): 49.83; Lung: 48.97; Prostate: 47.98; Breast - Mammary Tissue: 45.38; Vagina: 42.71; Brain - Nucleus accumbens (basal ganglia): 41.77; Brain - Caudate (basal ganglia): 40.85; Testis: 40.68; Heart - Left Ventricle: 35.09; Brain - Cerebellar Hemisphere: 34.34; Colon - Transverse: 33.58; Brain - Putamen (basal ganglia): 33.32; Spleen: 33.21; Brain - Cerebellum: 31.47; Brain - Frontal Cortex (BA9): 28.18; Brain - Cortex: 26.57; Brain - Spinal cord (cervical c-1): 26.43; Brain - Anterior cingulate cortex (BA24): 22.67; Skin - Sun Exposed (Lower leg): 22.63; Brain - Hypothalamus: 22.33; Brain - Substantia nigra: 20.81; Minor Salivary Gland: 18.30; Skin - Not Sun Exposed (Suprapubic): 17.53; Brain - Hippocampus: 17.48; Brain - Amygdala: 16.18; Stomach: 15.66; Pituitary: 15.53; Esophagus - Mucosa: 15.24; Small Intestine - Terminal Ileum: 14.31; Kidney - Cortex: 12.26; Muscle - Skeletal: 9.52; Pancreas: 8.53; Whole Blood: 3.13; Liver: 2.96; Cells - EBV-transformed lymphocytes: 0.35; MEAPAELLAALPALATALALLLAWLLVRRGAAASPEPARAPPEPAPPAEATGAPAPSRPCAPEPAASPAGPEEPGEPAGLGELGEPAGPGEPEGPGDPAAAPAEAEEQAVEARQEEEQDLDGEKGPSSEGPEEEDGEGFSFKYSPGKLRGNQYKKMMTKEELEEEQRVQKEQLAAIFKLMKDNKETFGEMSDGDVQEQLRLYDM MFSD11 UNC93-like protein MFSD11 MFS11_HUMAN (O43934-1) GO:0005215 (0.85) ! transporter activity; GO:0022857 (0.84) ! transmembrane transporter activity; GO:0022892 (0.78) ! substrate-specific transporter activity; GO:0022891 (0.77) ! substrate-specific transmembrane transporter activity; GO:0051119 (0.74) ! sugar transmembrane transporter activity; GO:0015145 (0.72) ! monosaccharide transmembrane transporter activity; GO:0015149 (0.71) ! hexose transmembrane transporter activity; GO:0005355 (0.70) ! glucose transmembrane transporter activity; GO:0008324 (0.67) ! cation transmembrane transporter activity; GO:0005351 (0.66) ! sugar:proton symporter activity; GO:0051183 (0.34) ! vitamin transporter activity; GO:0048029 (0.33) ! monosaccharide binding; GO:0015146 (0.33) ! pentose transmembrane transporter activity; GO:0015148 (0.32) ! D-xylose transmembrane transporter activity; GO:0009679 (0.27) ! hexose:proton symporter activity; GO:0005354 (0.27) ! galactose transmembrane transporter activity; GO:0042900 (0.26) ! arabinose transmembrane transporter activity; GO:0015459 (0.21) ! potassium channel regulator activity; GO:0005353 (0.05) ! fructose transmembrane transporter activity; GO:0015578 (0.03) ! mannose transmembrane transporter activity; GO:0015574 (0.03) ! trehalose transmembrane transporter activity; GO:0055056 (0.02) ! D-glucose transmembrane transporter activity; GO:0033300 (0.02) ! dehydroascorbic acid transporter activity; GO:0005536 (0.02) ! glucose binding; GO:0005342 (0.02) ! organic acid transmembrane transporter activity; GO:0070061 (0.01) ! fructose binding; GO:0055054 (0.01) ! fructose:proton symporter activity; GO:0046943 (0.01) ! carboxylic acid transmembrane transporter activity; GO:0046624 (0.01) ! sphingolipid transporter activity; GO:0043621 (0.01) ! protein self-association; GO:0035325 (0.01) ! Toll-like receptor binding; GO:0015233 (0.01) ! pantothenate transmembrane transporter activity; GO:0015143 (0.01) ! urate transmembrane transporter activity; GO:0005365 (0.01) ! myo-inositol transmembrane transporter activity; GO:0005358 (0.01) ! high-affinity hydrogen:glucose symporter activity GO:0006810 (0.82) ! transport; GO:0044699 (0.74) ! single-organism process; GO:0071702 (0.70) ! organic substance transport; GO:0055085 (0.69) ! transmembrane transport; GO:0008643 (0.68) ! carbohydrate transport; GO:0015749 (0.67) ! monosaccharide transport; GO:0008645 (0.66) ! hexose transport; GO:0015758 (0.64) ! glucose transport; GO:0034219 (0.61) ! carbohydrate transmembrane transport; GO:0035428 (0.60) ! hexose transmembrane transport; GO:0046323 (0.47) ! glucose import; GO:0065007 (0.38) ! biological regulation; GO:0050896 (0.38) ! response to stimulus; GO:0006820 (0.38) ! anion transport; GO:0051716 (0.35) ! cellular response to stimulus; GO:0042221 (0.34) ! response to chemical; GO:1901700 (0.33) ! response to oxygen-containing compound; GO:0071704 (0.33) ! organic substance metabolic process; GO:0044710 (0.33) ! single-organism metabolic process; GO:0044237 (0.33) ! cellular metabolic process; GO:0010033 (0.33) ! response to organic substance; GO:0098657 (0.32) ! import into cell; GO:0098704 (0.31) ! carbohydrate import across plasma membrane; GO:0044281 (0.31) ! small molecule metabolic process; GO:0015755 (0.31) ! fructose transport; GO:0015750 (0.31) ! pentose transport; GO:0015711 (0.31) ! organic anion transport; GO:0009746 (0.31) ! response to hexose; GO:0071331 (0.30) ! cellular response to hexose stimulus; GO:0051180 (0.30) ! vitamin transport; GO:0032445 (0.30) ! fructose import; GO:0019752 (0.30) ! carboxylic acid metabolic process; GO:0009750 (0.30) ! response to fructose; GO:0006767 (0.30) ! water-soluble vitamin metabolic process; GO:0003073 (0.30) ! regulation of systemic arterial blood pressure; GO:1904659 (0.29) ! glucose transmembrane transport; GO:0044723 (0.27) ! single-organism carbohydrate metabolic process; GO:0019318 (0.25) ! hexose metabolic process; GO:0050789 (0.10) ! regulation of biological process; GO:0051049 (0.08) ! regulation of transport; GO:0044351 (0.08) ! macropinocytosis; GO:0043266 (0.07) ! regulation of potassium ion transport; GO:0006937 (0.07) ! regulation of muscle contraction; GO:0048856 (0.06) ! anatomical structure development; GO:0044767 (0.06) ! single-organism developmental process; GO:0006950 (0.06) ! response to stress; GO:0003009 (0.06) ! skeletal muscle contraction; GO:0030587 (0.05) ! sorocarp development; GO:0043434 (0.04) ! response to peptide hormone; GO:0033993 (0.04) ! response to lipid; GO:0071548 (0.03) ! response to dexamethasone; GO:0032868 (0.03) ! response to insulin; GO:0050794 (0.02) ! regulation of cellular process; GO:0033692 (0.02) ! cellular polysaccharide biosynthetic process; GO:0016043 (0.02) ! cellular component organization; GO:0015791 (0.02) ! polyol transport; GO:0015771 (0.02) ! trehalose transport; GO:1990539 (0.01) ! fructose import across plasma membrane; GO:1903530 (0.01) ! regulation of secretion by cell; GO:0098708 (0.01) ! glucose import across plasma membrane; GO:0071332 (0.01) ! cellular response to fructose stimulus; GO:0070837 (0.01) ! dehydroascorbic acid transport; GO:0051050 (0.01) ! positive regulation of transport; GO:0048523 (0.01) ! negative regulation of cellular process; GO:0046415 (0.01) ! urate metabolic process; GO:0044755 (0.01) ! pantothenate import into cell; GO:0042886 (0.01) ! amide transport; GO:0040011 (0.01) ! locomotion; GO:0034162 (0.01) ! toll-like receptor 9 signaling pathway; GO:0034154 (0.01) ! toll-like receptor 7 signaling pathway; GO:0034138 (0.01) ! toll-like receptor 3 signaling pathway; GO:0023051 (0.01) ! regulation of signaling; GO:0015849 (0.01) ! organic acid transport; GO:0015798 (0.01) ! myo-inositol transport; GO:0015797 (0.01) ! mannitol transport; GO:0015795 (0.01) ! sorbitol transport; GO:0015770 (0.01) ! sucrose transport; GO:0010646 (0.01) ! regulation of cell communication; GO:0009749 (0.01) ! response to glucose; GO:0009628 (0.01) ! response to abiotic stimulus; GO:0008646 (0.01) ! high-affinity hexose transport; GO:0006886 (0.01) ! intracellular protein transport; GO:0006461 (0.01) ! protein complex assembly; GO:0003376 (0.01) ! sphingosine-1-phosphate signaling pathway; GO:0003044 (0.01) ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0016021 (1.00) ! integral component of membrane; GO:0016020 (1.00) ! membrane; GO:0044464 (0.95) ! cell part; GO:0005887 (0.77) ! integral component of plasma membrane; GO:0005886 (0.70) ! plasma membrane; GO:0044424 (0.20) ! intracellular part; GO:0044444 (0.19) ! cytoplasmic part; GO:0043226 (0.18) ! organelle; GO:0044422 (0.17) ! organelle part; GO:0043227 (0.17) ! membrane-bounded organelle; GO:0098590 (0.16) ! plasma membrane region; GO:0016324 (0.15) ! apical plasma membrane; GO:0043229 (0.13) ! intracellular organelle; GO:0044446 (0.12) ! intracellular organelle part; GO:0043231 (0.12) ! intracellular membrane-bounded organelle; GO:0044421 (0.11) ! extracellular region part; GO:0098588 (0.08) ! bounding membrane of organelle; GO:0031988 (0.08) ! membrane-bounded vesicle; GO:0070062 (0.07) ! extracellular exosome; GO:0042383 (0.07) ! sarcolemma; GO:0043234 (0.06) ! protein complex; GO:0016323 (0.06) ! basolateral plasma membrane; GO:0005622 (0.06) ! intracellular; GO:0055120 (0.05) ! striated muscle dense body; GO:0005737 (0.05) ! cytoplasm; GO:0098852 (0.04) ! lytic vacuole membrane; GO:0045121 (0.04) ! membrane raft; GO:0044431 (0.04) ! Golgi apparatus part; GO:0030864 (0.04) ! cortical actin cytoskeleton; GO:0016023 (0.04) ! cytoplasmic, membrane-bounded vesicle; GO:0005911 (0.04) ! cell-cell junction; GO:0005634 (0.04) ! nucleus; GO:0000323 (0.04) ! lytic vacuole; GO:0072562 (0.03) ! blood microparticle; GO:0043235 (0.03) ! receptor complex; GO:0042470 (0.03) ! melanosome; GO:0030496 (0.03) ! midbody; GO:0016328 (0.03) ! lateral plasma membrane; GO:0009579 (0.03) ! thylakoid; GO:0009535 (0.03) ! chloroplast thylakoid membrane; GO:0009507 (0.03) ! chloroplast; GO:0005901 (0.03) ! caveola; GO:0005829 (0.03) ! cytosol; GO:0005615 (0.03) ! extracellular space; GO:0005576 (0.03) ! extracellular region; GO:0001939 (0.03) ! female pronucleus; GO:0000329 (0.03) ! fungal-type vacuole membrane; GO:0000324 (0.03) ! fungal-type vacuole; GO:0000220 (0.03) ! vacuolar proton-transporting V-type ATPase, V0 domain; GO:0000139 (0.03) ! Golgi membrane; GO:0032009 (0.01) ! early phagosome; GO:0005794 (0.01) ! Golgi apparatus; GO:0005783 (0.01) ! endoplasmic reticulum; GO:0005768 (0.01) ! endosome; GO:0005765 (0.01) ! lysosomal membrane; GO:0005764 (0.01) ! lysosome GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 3 76735865-76781449 (17q25.1) Testis: 20.45; Vagina: 16.40; Pituitary: 15.56; Cervix - Endocervix: 15.05; Cervix - Ectocervix: 14.95; Artery - Aorta: 14.94; Uterus: 13.99; Nerve - Tibial: 13.55; Skin - Sun Exposed (Lower leg): 13.54; Skin - Not Sun Exposed (Suprapubic): 13.50; Thyroid: 13.34; Lung: 13.32; Artery - Coronary: 12.76; Esophagus - Mucosa: 12.60; Spleen: 11.89; Bladder: 11.68; Adipose - Subcutaneous: 11.65; Minor Salivary Gland: 11.48; Artery - Tibial: 11.30; Breast - Mammary Tissue: 11.17; Fallopian Tube: 11.10; Small Intestine - Terminal Ileum: 10.34; Adipose - Visceral (Omentum): 10.30; Prostate: 10.28; Ovary: 10.28; Colon - Transverse: 10.26; Adrenal Gland: 9.65; Cells - Transformed fibroblasts: 9.58; Colon - Sigmoid: 9.47; Brain - Cerebellar Hemisphere: 9.22; Stomach: 8.79; Esophagus - Gastroesophageal Junction: 8.75; Brain - Cerebellum: 8.53; Cells - EBV-transformed lymphocytes: 8.32; Esophagus - Muscularis: 7.81; Heart - Atrial Appendage: 7.68; Muscle - Skeletal: 7.39; Brain - Hypothalamus: 5.84; Brain - Frontal Cortex (BA9): 5.68; Brain - Spinal cord (cervical c-1): 5.61; Heart - Left Ventricle: 5.41; Brain - Cortex: 4.77; Liver: 4.76; Whole Blood: 4.71; Brain - Substantia nigra: 4.66; Kidney - Cortex: 4.51; Pancreas: 4.34; Brain - Nucleus accumbens (basal ganglia): 4.15; Brain - Anterior cingulate cortex (BA24): 4.02; Brain - Caudate (basal ganglia): 4.00; Brain - Hippocampus: 3.88; Brain - Amygdala: 3.54; Brain - Putamen (basal ganglia): 3.28; MSPESKKLFNIIILGVAFMFMFTAFQTCGNVAQTVIRSLNRTDFHGSGYTSMAIIYGVFSASNLITPSVVAIVGPQLSMFASGLFYSMYIAVFIQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHSIGRNSGIFWALLQSSLFFGNLYIYFAWQGKTQISESDRRTVFIALTVISLVGTVLFFLIRKPDSENVLGEDESSDDQDMEVNESAQNNLTKAVDAFKKSFKLCVTKEMLLLSITTAYTGLELTFFSGVYGTCIGATNKFGAEEKSLIGLSGIFIGIGEILGGSLFGLLSKNNRFGRNPVVLLGILVHFIAFYLIFLNMPGDAPIAPVKGTDSSAYIKSSKEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAIFKFVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTISFFTVEWEAAAFVARGSDYRSI C17orf99 Uncharacterized protein C17orf99 CQ099_HUMAN (Q6UX52-1) GO:0004872 (0.63) ! receptor activity; GO:0004888 (0.56) ! transmembrane signaling receptor activity; GO:0003824 (0.54) ! catalytic activity; GO:0004672 (0.53) ! protein kinase activity; GO:0019199 (0.50) ! transmembrane receptor protein kinase activity; GO:0097367 (0.49) ! carbohydrate derivative binding; GO:0035639 (0.47) ! purine ribonucleoside triphosphate binding; GO:0032559 (0.47) ! adenyl ribonucleotide binding; GO:0032550 (0.47) ! purine ribonucleoside binding; GO:0046983 (0.39) ! protein dimerization activity; GO:0072341 (0.25) ! modified amino acid binding; GO:0005543 (0.25) ! phospholipid binding; GO:0042802 (0.24) ! identical protein binding; GO:0005102 (0.21) ! receptor binding; GO:0042803 (0.18) ! protein homodimerization activity; GO:0050839 (0.16) ! cell adhesion molecule binding; GO:0004713 (0.08) ! protein tyrosine kinase activity; GO:0032403 (0.07) ! protein complex binding; GO:0003823 (0.07) ! antigen binding; GO:0008092 (0.06) ! cytoskeletal protein binding; GO:0008046 (0.06) ! axon guidance receptor activity; GO:0005198 (0.06) ! structural molecule activity; GO:0004714 (0.06) ! transmembrane receptor protein tyrosine kinase activity; GO:1901681 (0.04) ! sulfur compound binding; GO:0098772 (0.04) ! molecular function regulator; GO:0019838 (0.04) ! growth factor binding; GO:0008307 (0.04) ! structural constituent of muscle; GO:0003779 (0.04) ! actin binding; GO:0051393 (0.03) ! alpha-actinin binding; GO:0051015 (0.03) ! actin filament binding; GO:0030234 (0.03) ! enzyme regulator activity; GO:0019899 (0.03) ! enzyme binding; GO:0008201 (0.03) ! heparin binding; GO:0005178 (0.03) ! integrin binding; GO:0097493 (0.02) ! structural molecule activity conferring elasticity; GO:0070851 (0.02) ! growth factor receptor binding; GO:0051371 (0.02) ! muscle alpha-actinin binding; GO:0022891 (0.02) ! substrate-specific transmembrane transporter activity; GO:0019904 (0.02) ! protein domain specific binding; GO:0019900 (0.02) ! kinase binding; GO:0017134 (0.02) ! fibroblast growth factor binding; GO:0016787 (0.02) ! hydrolase activity; GO:0005200 (0.02) ! structural constituent of cytoskeleton; GO:0005021 (0.02) ! vascular endothelial growth factor-activated receptor activity; GO:0005007 (0.02) ! fibroblast growth factor-activated receptor activity; GO:0004860 (0.02) ! protein kinase inhibitor activity; GO:0004674 (0.02) ! protein serine/threonine kinase activity; GO:0098632 (0.01) ! protein binding involved in cell-cell adhesion; GO:0071253 (0.01) ! connexin binding; GO:0050840 (0.01) ! extracellular matrix binding; GO:0048495 (0.01) ! Roundabout binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0045296 (0.01) ! cadherin binding; GO:0043548 (0.01) ! phosphatidylinositol 3-kinase binding; GO:0043121 (0.01) ! neurotrophin binding; GO:0042287 (0.01) ! MHC protein binding; GO:0034987 (0.01) ! immunoglobulin receptor binding; GO:0030971 (0.01) ! receptor tyrosine kinase binding; GO:0030506 (0.01) ! ankyrin binding; GO:0030246 (0.01) ! carbohydrate binding; GO:0030165 (0.01) ! PDZ domain binding; GO:0019955 (0.01) ! cytokine binding; GO:0019903 (0.01) ! protein phosphatase binding; GO:0019865 (0.01) ! immunoglobulin binding; GO:0017022 (0.01) ! myosin binding; GO:0008047 (0.01) ! enzyme activator activity; GO:0008013 (0.01) ! beta-catenin binding; GO:0005244 (0.01) ! voltage-gated ion channel activity; GO:0005154 (0.01) ! epidermal growth factor receptor binding; GO:0005126 (0.01) ! cytokine receptor binding; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0005057 (0.01) ! receptor signaling protein activity; GO:0005042 (0.01) ! netrin receptor activity; GO:0005030 (0.01) ! neurotrophin receptor activity; GO:0005001 (0.01) ! transmembrane receptor protein tyrosine phosphatase activity; GO:0004687 (0.01) ! myosin light chain kinase activity; GO:0004683 (0.01) ! calmodulin-dependent protein kinase activity; GO:0001948 (0.01) ! glycoprotein binding GO:0044699 (0.79) ! single-organism process; GO:0009987 (0.76) ! cellular process; GO:0044763 (0.75) ! single-organism cellular process; GO:0032502 (0.68) ! developmental process; GO:0044767 (0.67) ! single-organism developmental process; GO:0048869 (0.61) ! cellular developmental process; GO:0016043 (0.61) ! cellular component organization; GO:0009653 (0.60) ! anatomical structure morphogenesis; GO:0006928 (0.58) ! movement of cell or subcellular component; GO:0065007 (0.56) ! biological regulation; GO:0050789 (0.55) ! regulation of biological process; GO:0048856 (0.54) ! anatomical structure development; GO:0030030 (0.54) ! cell projection organization; GO:0050794 (0.53) ! regulation of cellular process; GO:0032989 (0.53) ! cellular component morphogenesis; GO:0048812 (0.52) ! neuron projection morphogenesis; GO:0044238 (0.52) ! primary metabolic process; GO:0043170 (0.52) ! macromolecule metabolic process; GO:0016477 (0.52) ! cell migration; GO:0006796 (0.51) ! phosphate-containing compound metabolic process; GO:0006464 (0.51) ! cellular protein modification process; GO:0016310 (0.50) ! phosphorylation; GO:0061564 (0.48) ! axon development; GO:0032501 (0.48) ! multicellular organismal process; GO:0018212 (0.48) ! peptidyl-tyrosine modification; GO:0000904 (0.48) ! cell morphogenesis involved in differentiation; GO:0048667 (0.47) ! cell morphogenesis involved in neuron differentiation; GO:0003008 (0.44) ! system process; GO:0050877 (0.41) ! neurological system process; GO:0048598 (0.41) ! embryonic morphogenesis; GO:0007155 (0.41) ! cell adhesion; GO:0007600 (0.40) ! sensory perception; GO:0051239 (0.39) ! regulation of multicellular organismal process; GO:0050954 (0.39) ! sensory perception of mechanical stimulus; GO:0048840 (0.39) ! otolith development; GO:0042472 (0.39) ! inner ear morphogenesis; GO:0021675 (0.39) ! nerve development; GO:0050896 (0.38) ! response to stimulus; GO:0050793 (0.38) ! regulation of developmental process; GO:0048518 (0.38) ! positive regulation of biological process; GO:0007165 (0.38) ! signal transduction; GO:2000026 (0.37) ! regulation of multicellular organismal development; GO:0051128 (0.37) ! regulation of cellular component organization; GO:0048583 (0.37) ! regulation of response to stimulus; GO:0045595 (0.36) ! regulation of cell differentiation; GO:0048522 (0.35) ! positive regulation of cellular process; GO:0048519 (0.35) ! negative regulation of biological process; GO:0048513 (0.35) ! animal organ development; GO:0007166 (0.35) ! cell surface receptor signaling pathway; GO:0048523 (0.34) ! negative regulation of cellular process; GO:0009966 (0.33) ! regulation of signal transduction; GO:0051179 (0.32) ! localization; GO:0048584 (0.32) ! positive regulation of response to stimulus; GO:0042221 (0.32) ! response to chemical; GO:0032879 (0.31) ! regulation of localization; GO:0010033 (0.31) ! response to organic substance; GO:0009605 (0.31) ! response to external stimulus; GO:0006810 (0.31) ! transport; GO:0002682 (0.31) ! regulation of immune system process; GO:0002376 (0.31) ! immune system process; GO:1902531 (0.30) ! regulation of intracellular signal transduction; GO:0044765 (0.30) ! single-organism transport; GO:0044707 (0.30) ! single-multicellular organism process; GO:0043207 (0.30) ! response to external biotic stimulus; GO:0009967 (0.30) ! positive regulation of signal transduction; GO:1902533 (0.29) ! positive regulation of intracellular signal transduction; GO:0098602 (0.29) ! single organism cell adhesion; GO:0065008 (0.29) ! regulation of biological quality; GO:0051240 (0.29) ! positive regulation of multicellular organismal process; GO:0051130 (0.29) ! positive regulation of cellular component organization; GO:0051094 (0.29) ! positive regulation of developmental process; GO:0044702 (0.29) ! single organism reproductive process; GO:0042981 (0.29) ! regulation of apoptotic process; GO:0007169 (0.29) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0006955 (0.29) ! immune response; GO:0006950 (0.29) ! response to stress; GO:0006909 (0.29) ! phagocytosis; GO:0002684 (0.29) ! positive regulation of immune system process; GO:0002237 (0.29) ! response to molecule of bacterial origin; GO:0051716 (0.28) ! cellular response to stimulus; GO:0051704 (0.28) ! multi-organism process; GO:0051241 (0.28) ! negative regulation of multicellular organismal process; GO:0045597 (0.28) ! positive regulation of cell differentiation; GO:0043069 (0.28) ! negative regulation of programmed cell death; GO:0006952 (0.28) ! defense response; GO:0003006 (0.28) ! developmental process involved in reproduction; GO:1901700 (0.27) ! response to oxygen-containing compound; GO:0071310 (0.27) ! cellular response to organic substance; GO:0051049 (0.27) ! regulation of transport; GO:0050865 (0.27) ! regulation of cell activation; GO:0043066 (0.27) ! negative regulation of apoptotic process; GO:0042592 (0.27) ! homeostatic process; GO:2000106 (0.26) ! regulation of leukocyte apoptotic process; GO:1902105 (0.26) ! regulation of leukocyte differentiation; GO:1901701 (0.26) ! cellular response to oxygen-containing compound; GO:1901215 (0.26) ! negative regulation of neuron death; GO:0071396 (0.26) ! cellular response to lipid; GO:0071219 (0.26) ! cellular response to molecule of bacterial origin; GO:0051251 (0.26) ! positive regulation of lymphocyte activation; GO:0050878 (0.26) ! regulation of body fluid levels; GO:0048872 (0.26) ! homeostasis of number of cells; GO:0048608 (0.26) ! reproductive structure development; GO:0048511 (0.26) ! rhythmic process; GO:0048232 (0.26) ! male gamete generation; GO:0046903 (0.26) ! secretion; GO:0045807 (0.26) ! positive regulation of endocytosis; GO:0043523 (0.26) ! regulation of neuron apoptotic process; GO:0034097 (0.26) ! response to cytokine; GO:0032649 (0.26) ! regulation of interferon-gamma production; GO:0032496 (0.26) ! response to lipopolysaccharide; GO:0031589 (0.26) ! cell-substrate adhesion; GO:0016032 (0.26) ! viral process; GO:0002695 (0.26) ! negative regulation of leukocyte activation; GO:0001818 (0.26) ! negative regulation of cytokine production; GO:2000668 (0.25) ! regulation of dendritic cell apoptotic process; GO:2000107 (0.25) ! negative regulation of leukocyte apoptotic process; GO:1903556 (0.25) ! negative regulation of tumor necrosis factor superfamily cytokine production; GO:0071496 (0.25) ! cellular response to external stimulus; GO:0060760 (0.25) ! positive regulation of response to cytokine stimulus; GO:0051896 (0.25) ! regulation of protein kinase B signaling; GO:0048771 (0.25) ! tissue remodeling; GO:0048548 (0.25) ! regulation of pinocytosis; GO:0045621 (0.25) ! positive regulation of lymphocyte differentiation; GO:0035455 (0.25) ! response to interferon-alpha; GO:0032823 (0.25) ! regulation of natural killer cell differentiation; GO:0032816 (0.25) ! positive regulation of natural killer cell activation; GO:0032680 (0.25) ! regulation of tumor necrosis factor production; GO:0030900 (0.25) ! forebrain development; GO:0030540 (0.25) ! female genitalia development; GO:0030260 (0.25) ! entry into host cell; GO:0021700 (0.25) ! developmental maturation; GO:0019058 (0.25) ! viral life cycle; GO:0009991 (0.25) ! response to extracellular stimulus; GO:0007596 (0.25) ! blood coagulation; GO:0002262 (0.25) ! myeloid cell homeostasis; GO:0001959 (0.25) ! regulation of cytokine-mediated signaling pathway; GO:0098609 (0.17) ! cell-cell adhesion; GO:0008037 (0.15) ! cell recognition; GO:0022603 (0.13) ! regulation of anatomical structure morphogenesis; GO:0098742 (0.12) ! cell-cell adhesion via plasma-membrane adhesion molecules; GO:0050767 (0.12) ! regulation of neurogenesis; GO:0007411 (0.12) ! axon guidance; GO:0048468 (0.11) ! cell development; GO:0022604 (0.11) ! regulation of cell morphogenesis; GO:0010975 (0.11) ! regulation of neuron projection development; GO:0007156 (0.11) ! homophilic cell adhesion via plasma membrane adhesion molecules; GO:0019222 (0.10) ! regulation of metabolic process; GO:0080090 (0.09) ! regulation of primary metabolic process; GO:0060255 (0.09) ! regulation of macromolecule metabolic process; GO:0048646 (0.09) ! anatomical structure formation involved in morphogenesis; GO:0031323 (0.09) ! regulation of cellular metabolic process; GO:0007157 (0.09) ! heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; GO:0051246 (0.08) ! regulation of protein metabolic process; GO:0050770 (0.08) ! regulation of axonogenesis; GO:0048731 (0.08) ! system development; GO:0048589 (0.08) ! developmental growth; GO:0022607 (0.08) ! cellular component assembly; GO:0008038 (0.08) ! neuron recognition; GO:0007409 (0.08) ! axonogenesis; GO:1902589 (0.07) ! single-organism organelle organization; GO:0001932 (0.07) ! regulation of protein phosphorylation; GO:0065009 (0.06) ! regulation of molecular function; GO:0050776 (0.06) ! regulation of immune response; GO:0048675 (0.06) ! axon extension; GO:0040012 (0.06) ! regulation of locomotion; GO:0031325 (0.06) ! positive regulation of cellular metabolic process; GO:0030154 (0.06) ! cell differentiation; GO:0030036 (0.06) ! actin cytoskeleton organization; GO:0016337 (0.06) ! single organismal cell-cell adhesion; GO:0010604 (0.06) ! positive regulation of macromolecule metabolic process; GO:0009888 (0.06) ! tissue development; GO:0009628 (0.06) ! response to abiotic stimulus; GO:0006468 (0.06) ! protein phosphorylation; GO:2000145 (0.05) ! regulation of cell motility; GO:0051606 (0.05) ! detection of stimulus; GO:0050790 (0.05) ! regulation of catalytic activity; GO:0050773 (0.05) ! regulation of dendrite development; GO:0048846 (0.05) ! axon extension involved in axon guidance; GO:0048729 (0.05) ! tissue morphogenesis; GO:0048666 (0.05) ! neuron development; GO:0048585 (0.05) ! negative regulation of response to stimulus; GO:0042127 (0.05) ! regulation of cell proliferation; GO:0016319 (0.05) ! mushroom body development; GO:0009612 (0.05) ! response to mechanical stimulus; GO:0007422 (0.05) ! peripheral nervous system development; GO:0007419 (0.05) ! ventral cord development; GO:0007413 (0.05) ! axonal fasciculation; GO:0001934 (0.05) ! positive regulation of protein phosphorylation; GO:0070593 (0.04) ! dendrite self-avoidance; GO:0051962 (0.04) ! positive regulation of nervous system development; GO:0050976 (0.04) ! detection of mechanical stimulus involved in sensory perception of touch; GO:0050778 (0.04) ! positive regulation of immune response; GO:0048814 (0.04) ! regulation of dendrite morphogenesis; GO:0048638 (0.04) ! regulation of developmental growth; GO:0045859 (0.04) ! regulation of protein kinase activity; GO:0043410 (0.04) ! positive regulation of MAPK cascade; GO:0035556 (0.04) ! intracellular signal transduction; GO:0032490 (0.04) ! detection of molecule of bacterial origin; GO:0031347 (0.04) ! regulation of defense response; GO:0031032 (0.04) ! actomyosin structure organization; GO:0030334 (0.04) ! regulation of cell migration; GO:0021551 (0.04) ! central nervous system morphogenesis; GO:0010720 (0.04) ! positive regulation of cell development; GO:0009968 (0.04) ! negative regulation of signal transduction; GO:0009887 (0.04) ! organ morphogenesis; GO:0008284 (0.04) ! positive regulation of cell proliferation; GO:0061024 (0.03) ! membrane organization; GO:0060429 (0.03) ! epithelium development; GO:0055013 (0.03) ! cardiac muscle cell development; GO:0051248 (0.03) ! negative regulation of protein metabolic process; GO:0051093 (0.03) ! negative regulation of developmental process; GO:0048747 (0.03) ! muscle fiber development; GO:0046777 (0.03) ! protein autophosphorylation; GO:0045214 (0.03) ! sarcomere organization; GO:0045088 (0.03) ! regulation of innate immune response; GO:0043085 (0.03) ! positive regulation of catalytic activity; GO:0040017 (0.03) ! positive regulation of locomotion; GO:0035295 (0.03) ! tube development; GO:0032101 (0.03) ! regulation of response to external stimulus; GO:0031326 (0.03) ! regulation of cellular biosynthetic process; GO:0031324 (0.03) ! negative regulation of cellular metabolic process; GO:0010976 (0.03) ! positive regulation of neuron projection development; GO:0010927 (0.03) ! cellular component assembly involved in morphogenesis; GO:0010556 (0.03) ! regulation of macromolecule biosynthetic process; GO:0010468 (0.03) ! regulation of gene expression; GO:0008045 (0.03) ! motor neuron axon guidance; GO:0007389 (0.03) ! pattern specification process; GO:0007154 (0.03) ! cell communication; GO:0007015 (0.03) ! actin filament organization; GO:0006936 (0.03) ! muscle contraction; GO:0002706 (0.03) ! regulation of lymphocyte mediated immunity; GO:0002252 (0.03) ! immune effector process; GO:0002009 (0.03) ! morphogenesis of an epithelium; GO:0001775 (0.03) ! cell activation; GO:0001667 (0.03) ! ameboidal-type cell migration; GO:0001558 (0.03) ! regulation of cell growth; GO:1902580 (0.02) ! single-organism cellular localization; GO:0071900 (0.02) ! regulation of protein serine/threonine kinase activity; GO:0071495 (0.02) ! cellular response to endogenous stimulus; GO:0070372 (0.02) ! regulation of ERK1 and ERK2 cascade; GO:0061061 (0.02) ! muscle structure development; GO:0060249 (0.02) ! anatomical structure homeostasis; GO:0055008 (0.02) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.02) ! cardiac myofibril assembly; GO:0051707 (0.02) ! response to other organism; GO:0051493 (0.02) ! regulation of cytoskeleton organization; GO:0051345 (0.02) ! positive regulation of hydrolase activity; GO:0051129 (0.02) ! negative regulation of cellular component organization; GO:0051046 (0.02) ! regulation of secretion; GO:0050900 (0.02) ! leukocyte migration; GO:0050772 (0.02) ! positive regulation of axonogenesis; GO:0050768 (0.02) ! negative regulation of neurogenesis; GO:0050678 (0.02) ! regulation of epithelial cell proliferation; GO:0048739 (0.02) ! cardiac muscle fiber development; GO:0048639 (0.02) ! positive regulation of developmental growth; GO:0046649 (0.02) ! lymphocyte activation; GO:0046426 (0.02) ! negative regulation of JAK-STAT cascade; GO:0045954 (0.02) ! positive regulation of natural killer cell mediated cytotoxicity; GO:0045860 (0.02) ! positive regulation of protein kinase activity; GO:0045785 (0.02) ! positive regulation of cell adhesion; GO:0045216 (0.02) ! cell-cell junction organization; GO:0045087 (0.02) ! innate immune response; GO:0044802 (0.02) ! single-organism membrane organization; GO:0044710 (0.02) ! single-organism metabolic process; GO:0042493 (0.02) ! response to drug; GO:0035385 (0.02) ! Roundabout signaling pathway; GO:0035239 (0.02) ! tube morphogenesis; GO:0034109 (0.02) ! homotypic cell-cell adhesion; GO:0033554 (0.02) ! cellular response to stress; GO:0032940 (0.02) ! secretion by cell; GO:0032102 (0.02) ! negative regulation of response to external stimulus; GO:0031328 (0.02) ! positive regulation of cellular biosynthetic process; GO:0031290 (0.02) ! retinal ganglion cell axon guidance; GO:0030516 (0.02) ! regulation of axon extension; GO:0030335 (0.02) ! positive regulation of cell migration; GO:0030241 (0.02) ! skeletal muscle myosin thick filament assembly; GO:0030198 (0.02) ! extracellular matrix organization; GO:0030182 (0.02) ! neuron differentiation; GO:0030097 (0.02) ! hemopoiesis; GO:0030031 (0.02) ! cell projection assembly; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0022407 (0.02) ! regulation of cell-cell adhesion; GO:0019221 (0.02) ! cytokine-mediated signaling pathway; GO:0018108 (0.02) ! peptidyl-tyrosine phosphorylation; GO:0010631 (0.02) ! epithelial cell migration; GO:0010628 (0.02) ! positive regulation of gene expression; GO:0010557 (0.02) ! positive regulation of macromolecule biosynthetic process; GO:0009886 (0.02) ! post-embryonic morphogenesis; GO:0009611 (0.02) ! response to wounding; GO:0008543 (0.02) ! fibroblast growth factor receptor signaling pathway; GO:0008360 (0.02) ! regulation of cell shape; GO:0008285 (0.02) ! negative regulation of cell proliferation; GO:0008283 (0.02) ! cell proliferation; GO:0008104 (0.02) ! protein localization; GO:0007610 (0.02) ! behavior; GO:0007420 (0.02) ! brain development; GO:0007416 (0.02) ! synapse assembly; GO:0007399 (0.02) ! nervous system development; GO:0007267 (0.02) ! cell-cell signaling; GO:0007163 (0.02) ! establishment or maintenance of cell polarity; GO:0007159 (0.02) ! leukocyte cell-cell adhesion; GO:0006959 (0.02) ! humoral immune response; GO:0006941 (0.02) ! striated muscle contraction; GO:0006935 (0.02) ! chemotaxis; GO:0006469 (0.02) ! negative regulation of protein kinase activity; GO:0006355 (0.02) ! regulation of transcription, DNA-templated; GO:0003002 (0.02) ! regionalization; GO:0002831 (0.02) ! regulation of response to biotic stimulus; GO:0002768 (0.02) ! immune response-regulating cell surface receptor signaling pathway; GO:0001764 (0.02) ! neuron migration; GO:0001525 (0.02) ! angiogenesis; GO:2001262 (0.01) ! positive regulation of semaphorin-plexin signaling pathway; GO:2000027 (0.01) ! regulation of organ morphogenesis; GO:1904018 (0.01) ! positive regulation of vasculature development; GO:1903859 (0.01) ! regulation of dendrite extension; GO:1903532 (0.01) ! positive regulation of secretion by cell; GO:1903531 (0.01) ! negative regulation of secretion by cell; GO:1903034 (0.01) ! regulation of response to wounding; GO:1902582 (0.01) ! single-organism intracellular transport; GO:1900006 (0.01) ! positive regulation of dendrite development; GO:0098771 (0.01) ! inorganic ion homeostasis; GO:0097205 (0.01) ! renal filtration; GO:0090287 (0.01) ! regulation of cellular response to growth factor stimulus; GO:0090066 (0.01) ! regulation of anatomical structure size; GO:0086067 (0.01) ! AV node cell to bundle of His cell communication; GO:0072657 (0.01) ! protein localization to membrane; GO:0072347 (0.01) ! response to anesthetic; GO:0071363 (0.01) ! cellular response to growth factor stimulus; GO:0070527 (0.01) ! platelet aggregation; GO:0070482 (0.01) ! response to oxygen levels; GO:0070374 (0.01) ! positive regulation of ERK1 and ERK2 cascade; GO:0070050 (0.01) ! neuron cellular homeostasis; GO:0061327 (0.01) ! anterior Malpighian tubule development; GO:0060828 (0.01) ! regulation of canonical Wnt signaling pathway; GO:0060370 (0.01) ! susceptibility to T cell mediated cytotoxicity; GO:0060341 (0.01) ! regulation of cellular localization; GO:0051963 (0.01) ! regulation of synapse assembly; GO:0051924 (0.01) ! regulation of calcium ion transport; GO:0051726 (0.01) ! regulation of cell cycle; GO:0051656 (0.01) ! establishment of organelle localization; GO:0051222 (0.01) ! positive regulation of protein transport; GO:0051147 (0.01) ! regulation of muscle cell differentiation; GO:0050922 (0.01) ! negative regulation of chemotaxis; GO:0050921 (0.01) ! positive regulation of chemotaxis; GO:0050919 (0.01) ! negative chemotaxis; GO:0050871 (0.01) ! positive regulation of B cell activation; GO:0050868 (0.01) ! negative regulation of T cell activation; GO:0050853 (0.01) ! B cell receptor signaling pathway; GO:0050804 (0.01) ! modulation of synaptic transmission; GO:0050803 (0.01) ! regulation of synapse structure or activity; GO:0050792 (0.01) ! regulation of viral process; GO:0050766 (0.01) ! positive regulation of phagocytosis; GO:0050731 (0.01) ! positive regulation of peptidyl-tyrosine phosphorylation; GO:0050728 (0.01) ! negative regulation of inflammatory response; GO:0050707 (0.01) ! regulation of cytokine secretion; GO:0050680 (0.01) ! negative regulation of epithelial cell proliferation; GO:0050679 (0.01) ! positive regulation of epithelial cell proliferation; GO:0050673 (0.01) ! epithelial cell proliferation; GO:0048863 (0.01) ! stem cell differentiation; GO:0048841 (0.01) ! regulation of axon extension involved in axon guidance; GO:0048813 (0.01) ! dendrite morphogenesis; GO:0048803 (0.01) ! imaginal disc-derived male genitalia morphogenesis; GO:0048738 (0.01) ! cardiac muscle tissue development; GO:0048732 (0.01) ! gland development; GO:0048678 (0.01) ! response to axon injury; GO:0048661 (0.01) ! positive regulation of smooth muscle cell proliferation; GO:0048644 (0.01) ! muscle organ morphogenesis; GO:0048568 (0.01) ! embryonic organ development; GO:0048565 (0.01) ! digestive tract development; GO:0048562 (0.01) ! embryonic organ morphogenesis; GO:0048514 (0.01) ! blood vessel morphogenesis; GO:0048015 (0.01) ! phosphatidylinositol-mediated signaling; GO:0048010 (0.01) ! vascular endothelial growth factor receptor signaling pathway; GO:0046651 (0.01) ! lymphocyte proliferation; GO:0046634 (0.01) ! regulation of alpha-beta T cell activation; GO:0046620 (0.01) ! regulation of organ growth; GO:0046579 (0.01) ! positive regulation of Ras protein signal transduction; GO:0046331 (0.01) ! lateral inhibition; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045892 (0.01) ! negative regulation of transcription, DNA-templated; GO:0045824 (0.01) ! negative regulation of innate immune response; GO:0045773 (0.01) ! positive regulation of axon extension; GO:0045670 (0.01) ! regulation of osteoclast differentiation; GO:0045610 (0.01) ! regulation of hemocyte differentiation; GO:0045576 (0.01) ! mast cell activation; GO:0045199 (0.01) ! maintenance of epithelial cell apical/basal polarity; GO:0045165 (0.01) ! cell fate commitment; GO:0045055 (0.01) ! regulated exocytosis; GO:0044089 (0.01) ! positive regulation of cellular component biogenesis; GO:0044057 (0.01) ! regulation of system process; GO:0043534 (0.01) ! blood vessel endothelial cell migration; GO:0043524 (0.01) ! negative regulation of neuron apoptotic process; GO:0043491 (0.01) ! protein kinase B signaling; GO:0043277 (0.01) ! apoptotic cell clearance; GO:0043087 (0.01) ! regulation of GTPase activity; GO:0043065 (0.01) ! positive regulation of apoptotic process; GO:0043009 (0.01) ! chordate embryonic development; GO:0042742 (0.01) ! defense response to bacterium; GO:0042698 (0.01) ! ovulation cycle; GO:0042271 (0.01) ! susceptibility to natural killer cell mediated cytotoxicity; GO:0042246 (0.01) ! tissue regeneration; GO:0042102 (0.01) ! positive regulation of T cell proliferation; GO:0042060 (0.01) ! wound healing; GO:0042059 (0.01) ! negative regulation of epidermal growth factor receptor signaling pathway; GO:0042035 (0.01) ! regulation of cytokine biosynthetic process; GO:0038202 (0.01) ! TORC1 signaling; GO:0038093 (0.01) ! Fc receptor signaling pathway; GO:0036335 (0.01) ! intestinal stem cell homeostasis; GO:0035282 (0.01) ! segmentation; GO:0035172 (0.01) ! hemocyte proliferation; GO:0035167 (0.01) ! larval lymph gland hemopoiesis; GO:0035107 (0.01) ! appendage morphogenesis; GO:0035099 (0.01) ! hemocyte migration; GO:0034446 (0.01) ! substrate adhesion-dependent cell spreading; GO:0034332 (0.01) ! adherens junction organization; GO:0034122 (0.01) ! negative regulation of toll-like receptor signaling pathway; GO:0034103 (0.01) ! regulation of tissue remodeling; GO:0033564 (0.01) ! anterior/posterior axon guidance; GO:0032956 (0.01) ! regulation of actin cytoskeleton organization; GO:0032869 (0.01) ! cellular response to insulin stimulus; GO:0032844 (0.01) ! regulation of homeostatic process; GO:0032693 (0.01) ! negative regulation of interleukin-10 production; GO:0031532 (0.01) ! actin cytoskeleton reorganization; GO:0031102 (0.01) ! neuron projection regeneration; GO:0030855 (0.01) ! epithelial cell differentiation; GO:0030593 (0.01) ! neutrophil chemotaxis; GO:0030517 (0.01) ! negative regulation of axon extension; GO:0030336 (0.01) ! negative regulation of cell migration; GO:0030240 (0.01) ! skeletal muscle thin filament assembly; GO:0030217 (0.01) ! T cell differentiation; GO:0030183 (0.01) ! B cell differentiation; GO:0030168 (0.01) ! platelet activation; GO:0030162 (0.01) ! regulation of proteolysis; GO:0022602 (0.01) ! ovulation cycle process; GO:0022411 (0.01) ! cellular component disassembly; GO:0021954 (0.01) ! central nervous system neuron development; GO:0021952 (0.01) ! central nervous system projection neuron axonogenesis; GO:0021885 (0.01) ! forebrain cell migration; GO:0019730 (0.01) ! antimicrobial humoral response; GO:0019233 (0.01) ! sensory perception of pain; GO:0019216 (0.01) ! regulation of lipid metabolic process; GO:0016525 (0.01) ! negative regulation of angiogenesis; GO:0016331 (0.01) ! morphogenesis of embryonic epithelium; GO:0016202 (0.01) ! regulation of striated muscle tissue development; GO:0016199 (0.01) ! axon midline choice point recognition; GO:0015031 (0.01) ! protein transport; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0014068 (0.01) ! positive regulation of phosphatidylinositol 3-kinase signaling; GO:0010906 (0.01) ! regulation of glucose metabolic process; GO:0010863 (0.01) ! positive regulation of phospholipase C activity; GO:0010842 (0.01) ! retina layer formation; GO:0010669 (0.01) ! epithelial structure maintenance; GO:0010638 (0.01) ! positive regulation of organelle organization; GO:0010594 (0.01) ! regulation of endothelial cell migration; GO:0010453 (0.01) ! regulation of cell fate commitment; GO:0010035 (0.01) ! response to inorganic substance; GO:0009952 (0.01) ! anterior/posterior pattern specification; GO:0008589 (0.01) ! regulation of smoothened signaling pathway; GO:0008406 (0.01) ! gonad development; GO:0008366 (0.01) ! axon ensheathment; GO:0008354 (0.01) ! germ cell migration; GO:0008039 (0.01) ! synaptic target recognition; GO:0007626 (0.01) ! locomotory behavior; GO:0007611 (0.01) ! learning or memory; GO:0007606 (0.01) ! sensory perception of chemical stimulus; GO:0007565 (0.01) ! female pregnancy; GO:0007528 (0.01) ! neuromuscular junction development; GO:0007520 (0.01) ! myoblast fusion; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007517 (0.01) ! muscle organ development; GO:0007516 (0.01) ! hemocyte development; GO:0007507 (0.01) ! heart development; GO:0007498 (0.01) ! mesoderm development; GO:0007443 (0.01) ! Malpighian tubule morphogenesis; GO:0007435 (0.01) ! salivary gland morphogenesis; GO:0007432 (0.01) ! salivary gland boundary specification; GO:0007423 (0.01) ! sensory organ development; GO:0007417 (0.01) ! central nervous system development; GO:0007415 (0.01) ! defasciculation of motor neuron axon; GO:0007298 (0.01) ! border follicle cell migration; GO:0007283 (0.01) ! spermatogenesis; GO:0007281 (0.01) ! germ cell development; GO:0007224 (0.01) ! smoothened signaling pathway; GO:0007043 (0.01) ! cell-cell junction assembly; GO:0007005 (0.01) ! mitochondrion organization; GO:0006974 (0.01) ! cellular response to DNA damage stimulus; GO:0006958 (0.01) ! complement activation, classical pathway; GO:0006954 (0.01) ! inflammatory response; GO:0006939 (0.01) ! smooth muscle contraction; GO:0006911 (0.01) ! phagocytosis, engulfment; GO:0006910 (0.01) ! phagocytosis, recognition; GO:0006898 (0.01) ! receptor-mediated endocytosis; GO:0006470 (0.01) ! protein dephosphorylation; GO:0003013 (0.01) ! circulatory system process; GO:0002860 (0.01) ! positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; GO:0002573 (0.01) ! myeloid leukocyte differentiation; GO:0002443 (0.01) ! leukocyte mediated immunity; GO:0002377 (0.01) ! immunoglobulin production; GO:0002366 (0.01) ! leukocyte activation involved in immune response; GO:0002064 (0.01) ! epithelial cell development; GO:0001936 (0.01) ! regulation of endothelial cell proliferation; GO:0001837 (0.01) ! epithelial to mesenchymal transition; GO:0001819 (0.01) ! positive regulation of cytokine production; GO:0001754 (0.01) ! eye photoreceptor cell differentiation; GO:0001745 (0.01) ! compound eye morphogenesis; GO:0001708 (0.01) ! cell fate specification; GO:0001657 (0.01) ! ureteric bud development; GO:0001569 (0.01) ! patterning of blood vessels; GO:0001568 (0.01) ! blood vessel development; GO:0000187 (0.01) ! activation of MAPK activity; GO:0000165 (0.01) ! MAPK cascade; GO:0000022 (0.01) ! mitotic spindle elongation GO:0031224 (1.00) ! intrinsic component of membrane; GO:0016020 (1.00) ! membrane; GO:0044464 (0.98) ! cell part; GO:0016021 (0.95) ! integral component of membrane; GO:0005886 (0.90) ! plasma membrane; GO:0044459 (0.75) ! plasma membrane part; GO:0005887 (0.63) ! integral component of plasma membrane; GO:0043226 (0.50) ! organelle; GO:0043227 (0.49) ! membrane-bounded organelle; GO:0031982 (0.42) ! vesicle; GO:0097458 (0.41) ! neuron part; GO:0044424 (0.41) ! intracellular part; GO:0042995 (0.40) ! cell projection; GO:0031988 (0.38) ! membrane-bounded vesicle; GO:0009986 (0.38) ! cell surface; GO:0043005 (0.35) ! neuron projection; GO:0030054 (0.35) ! cell junction; GO:0030424 (0.34) ! axon; GO:0044421 (0.32) ! extracellular region part; GO:0044444 (0.28) ! cytoplasmic part; GO:0043234 (0.28) ! protein complex; GO:0043229 (0.26) ! intracellular organelle; GO:0005912 (0.25) ! adherens junction; GO:0070062 (0.24) ! extracellular exosome; GO:0044463 (0.24) ! cell projection part; GO:0043231 (0.24) ! intracellular membrane-bounded organelle; GO:0005911 (0.24) ! cell-cell junction; GO:0005737 (0.24) ! cytoplasm; GO:0045202 (0.22) ! synapse; GO:0044422 (0.22) ! organelle part; GO:0044297 (0.21) ! cell body; GO:0043025 (0.20) ! neuronal cell body; GO:0005576 (0.19) ! extracellular region; GO:0098590 (0.17) ! plasma membrane region; GO:0005634 (0.17) ! nucleus; GO:0016023 (0.16) ! cytoplasmic, membrane-bounded vesicle; GO:0005913 (0.16) ! cell-cell adherens junction; GO:0044446 (0.15) ! intracellular organelle part; GO:0030425 (0.13) ! dendrite; GO:0005615 (0.13) ! extracellular space; GO:0098797 (0.11) ! plasma membrane protein complex; GO:0005794 (0.11) ! Golgi apparatus; GO:0044428 (0.10) ! nuclear part; GO:0031225 (0.10) ! anchored component of membrane; GO:0009897 (0.10) ! external side of plasma membrane; GO:0031012 (0.09) ! extracellular matrix; GO:0043235 (0.08) ! receptor complex; GO:0033267 (0.08) ! axon part; GO:0030426 (0.08) ! growth cone; GO:0005925 (0.08) ! focal adhesion; GO:0005654 (0.08) ! nucleoplasm; GO:0097060 (0.07) ! synaptic membrane; GO:0044449 (0.07) ! contractile fiber part; GO:0005938 (0.07) ! cell cortex; GO:0060076 (0.06) ! excitatory synapse; GO:0032584 (0.06) ! growth cone membrane; GO:0005622 (0.06) ! intracellular; GO:0045121 (0.05) ! membrane raft; GO:0044430 (0.05) ! cytoskeletal part; GO:0030018 (0.05) ! Z disc; GO:0005829 (0.05) ! cytosol; GO:0098588 (0.04) ! bounding membrane of organelle; GO:0045211 (0.04) ! postsynaptic membrane; GO:0044295 (0.04) ! axonal growth cone; GO:0044291 (0.04) ! cell-cell contact zone; GO:0043232 (0.04) ! intracellular non-membrane-bounded organelle; GO:0042101 (0.04) ! T cell receptor complex; GO:0031594 (0.04) ! neuromuscular junction; GO:0031430 (0.04) ! M band; GO:0031253 (0.04) ! cell projection membrane; GO:0016323 (0.04) ! basolateral plasma membrane; GO:0005783 (0.04) ! endoplasmic reticulum; GO:1990682 (0.03) ! CSF1-CSF1R complex; GO:0071666 (0.03) ! Slit-Robo signaling complex; GO:0071575 (0.03) ! integral component of external side of plasma membrane; GO:0060170 (0.03) ! ciliary membrane; GO:0044228 (0.03) ! host cell surface; GO:0044224 (0.03) ! juxtaparanode region of axon; GO:0043209 (0.03) ! myelin sheath; GO:0042734 (0.03) ! presynaptic membrane; GO:0033268 (0.03) ! node of Ranvier; GO:0031526 (0.03) ! brush border membrane; GO:0030133 (0.03) ! transport vesicle; GO:0016342 (0.03) ! catenin complex; GO:0016328 (0.03) ! lateral plasma membrane; GO:0016324 (0.03) ! apical plasma membrane; GO:0009925 (0.03) ! basal plasma membrane; GO:0008076 (0.03) ! voltage-gated potassium channel complex; GO:0005915 (0.03) ! zonula adherens; GO:0005604 (0.03) ! basement membrane; GO:0005865 (0.02) ! striated muscle thin filament; GO:0005859 (0.02) ! muscle myosin complex; GO:0005623 (0.02) ! cell; GO:0005578 (0.02) ! proteinaceous extracellular matrix; GO:0072562 (0.01) ! blood microparticle; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0042571 (0.01) ! immunoglobulin complex, circulating; GO:0032589 (0.01) ! neuron projection membrane; GO:0031674 (0.01) ! I band; GO:0031672 (0.01) ! A band; GO:0030175 (0.01) ! filopodium; GO:0030017 (0.01) ! sarcomere; GO:0016327 (0.01) ! apicolateral plasma membrane; GO:0014704 (0.01) ! intercalated disc; GO:0005923 (0.01) ! bicellular tight junction; GO:0005917 (0.01) ! nephrocyte diaphragm; GO:0005875 (0.01) ! microtubule associated complex; GO:0005856 (0.01) ! cytoskeleton; GO:0005811 (0.01) ! lipid particle; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005769 (0.01) ! early endosome; GO:0005635 (0.01) ! nuclear envelope; GO:0001669 (0.01) ! acrosomal vesicle GO:0002313 ! mature B cell differentiation involved in immune response; GO:0005615 ! extracellular space; GO:2000558 ! positive regulation of immunoglobulin production in mucosal tissue GO:0005576 ! extracellular region 2 78146353-78166177 (17q25.3) Cells - EBV-transformed lymphocytes: 3.62; Skin - Not Sun Exposed (Suprapubic): 0.37; Whole Blood: 0.36; Skin - Sun Exposed (Lower leg): 0.32; Spleen: 0.20; Vagina: 0.20; Esophagus - Mucosa: 0.15; Fallopian Tube: 0.11; Nerve - Tibial: 0.11; Ovary: 0.10; Lung: 0.10; Minor Salivary Gland: 0.09; Testis: 0.08; Small Intestine - Terminal Ileum: 0.08; Bladder: 0.07; Prostate: 0.06; Adipose - Subcutaneous: 0.05; Breast - Mammary Tissue: 0.05; Uterus: 0.04; Cervix - Ectocervix: 0.04; Colon - Transverse: 0.04; Adipose - Visceral (Omentum): 0.03; Esophagus - Gastroesophageal Junction: 0.03; Brain - Spinal cord (cervical c-1): 0.02; Colon - Sigmoid: 0.02; Brain - Substantia nigra: 0.02; Esophagus - Muscularis: 0.02; Pituitary: 0.02; Kidney - Cortex: 0.02; Brain - Putamen (basal ganglia): 0.01; Brain - Caudate (basal ganglia): 0.01; Brain - Hypothalamus: 0.01; Liver: 0.01; Brain - Hippocampus: 0.01; Brain - Anterior cingulate cortex (BA24): 0.01; Pancreas: 0.01; MGLPGLFCLAVLAASSFSKAREEEITPVVSIAYKVLEVFPKGRWVLITCCAPQPPPPITYSLCGTKNIKVAKKVVKTHEPASFNLNVTLKSSPDLLTYFCWASSTSGAHVDSARLQMHWELWSKPVSELRANFTLQDRGAGPRVEMICQASSGSPPITNSLIGKDGQVHLQQRPCHRQPANFSFLPSQTSDWFWCQAANNANVQHSALTVVPPGGDQKMEDWQGPLESPILALPLYRSTRRLSEEEFGGFRIGNGEVRGRKAAAM SYNGR2 Synaptogyrin-2 SNG2_HUMAN (O43760-1) GO:0043169 (0.37) ! cation binding; GO:0047485 (0.23) ! protein N-terminus binding; GO:0042169 (0.23) ! SH2 domain binding; GO:0016462 (0.22) ! pyrophosphatase activity; GO:0015405 (0.22) ! P-P-bond-hydrolysis-driven transmembrane transporter activity GO:0006810 (0.66) ! transport; GO:0051649 (0.64) ! establishment of localization in cell; GO:0051641 (0.64) ! cellular localization; GO:0006605 (0.52) ! protein targeting; GO:0065007 (0.51) ! biological regulation; GO:0050789 (0.51) ! regulation of biological process; GO:0051049 (0.31) ! regulation of transport; GO:0032411 (0.26) ! positive regulation of transporter activity; GO:0050794 (0.25) ! regulation of cellular process; GO:0044699 (0.25) ! single-organism process; GO:0048168 (0.20) ! regulation of neuronal synaptic plasticity; GO:0048172 (0.19) ! regulation of short-term neuronal synaptic plasticity; GO:0048169 (0.19) ! regulation of long-term neuronal synaptic plasticity; GO:0044765 (0.16) ! single-organism transport; GO:0048489 (0.12) ! synaptic vesicle transport; GO:0021762 (0.09) ! substantia nigra development; GO:0022008 (0.06) ! neurogenesis; GO:0016079 (0.06) ! synaptic vesicle exocytosis; GO:0017157 (0.05) ! regulation of exocytosis; GO:0015672 (0.05) ! monovalent inorganic cation transport; GO:0006818 (0.05) ! hydrogen transport GO:0031594 (1.00) ! neuromuscular junction; GO:0030672 (1.00) ! synaptic vesicle membrane; GO:0031988 (0.13) ! membrane-bounded vesicle; GO:0008021 (0.10) ! synaptic vesicle; GO:0070062 (0.06) ! extracellular exosome; GO:0016021 (0.06) ! integral component of membrane; GO:0043195 (0.01) ! terminal bouton May play a role in regulated exocytosis. In neuronal cells, modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in the formation and/or the maturation of this vesicles. May also play a role in GLUT4 storage and transport to the plasma membrane. {ECO:0000250|UniProtKB:O54980}. (Microbial infection) May play a role in the assembly of cytoplasmic inclusion bodies required for SFTS phlebovirus replication. {ECO:0000269|PubMed:27226560}. GO:0030672 ! synaptic vesicle membrane; GO:0005515 ! protein binding; GO:0070062 ! extracellular exosome; GO:0016021 ! integral component of membrane; GO:0048499 ! synaptic vesicle membrane organization; GO:0045055 ! regulated exocytosis; GO:0031594 ! neuromuscular junction GO:0030054 ! cell junction; GO:0005811 ! lipid droplet; GO:0031410 ! cytoplasmic vesicle; GO:0045202 ! synapse; GO:0016020 ! membrane; GO:0008021 ! synaptic vesicle; GO:0030659 ! cytoplasmic vesicle membrane 5 GO:0045055 ! regulated exocytosis; GO:0048499 ! synaptic vesicle membrane organization; GO:0005515 ! protein binding 78168558-78173527 (17q25.3) High: prostate (glandular cells);Medium: stomach 2 (glandular cells);stomach 1 (glandular cells);colon (glandular cells);gallbladder (glandular cells);tonsil (germinal center cells; non-germinal center cells; squamous epithelial cells);thyroid gland (glandular cells);epididymis (glandular cells);adrenal gland (glandular cells);endometrium 2 (glandular cells);salivary gland (glandular cells);duodenum (glandular cells);cerebral cortex (endothelial cells);lymph node (germinal center cells; non-germinal center cells);parathyroid gland (glandular cells);urinary bladder (urothelial cells);small intestine (glandular cells);breast (glandular cells);rectum (glandular cells);pancreas (exocrine glandular cells);placenta (trophoblastic cells);fallopian tube (glandular cells);spleen (cells in red pulp; cells in white pulp);appendix (glandular cells; lymphoid tissue);nasopharynx (respiratory epithelial cells);lung (macrophages);skin 2 (epidermal cells);Low: kidney (cells in tubules);bone marrow (hematopoietic cells);skin 1 (keratinocytes; melanocytes);endometrium 1 (glandular cells);seminal vesicle (glandular cells);breast (myoepithelial cells);esophagus (squamous epithelial cells);oral mucosa (squamous epithelial cells);cerebral cortex (glial cells);cervix, uterine (squamous epithelial cells); Cells - EBV-transformed lymphocytes: 348.30; Lung: 133.40; Spleen: 112.15; Minor Salivary Gland: 107.80; Prostate: 105.60; Skin - Not Sun Exposed (Suprapubic): 100.60; Skin - Sun Exposed (Lower leg): 100.50; Artery - Aorta: 90.22; Muscle - Skeletal: 89.39; Artery - Coronary: 80.53; Esophagus - Gastroesophageal Junction: 78.02; Brain - Spinal cord (cervical c-1): 75.15; Small Intestine - Terminal Ileum: 75.04; Esophagus - Mucosa: 74.43; Esophagus - Muscularis: 74.11; Pituitary: 73.59; Whole Blood: 71.61; Stomach: 70.48; Breast - Mammary Tissue: 69.88; Colon - Transverse: 67.47; Vagina: 64.60; Nerve - Tibial: 64.31; Artery - Tibial: 62.90; Bladder: 62.57; Adipose - Subcutaneous: 62.42; Thyroid: 61.09; Fallopian Tube: 57.39; Cervix - Endocervix: 53.84; Adipose - Visceral (Omentum): 53.40; Pancreas: 51.82; Uterus: 50.29; Cervix - Ectocervix: 48.41; Kidney - Cortex: 39.12; Ovary: 37.52; Heart - Left Ventricle: 37.21; Heart - Atrial Appendage: 34.36; Adrenal Gland: 32.48; Testis: 29.67; Brain - Cerebellum: 29.67; Colon - Sigmoid: 29.24; Brain - Cerebellar Hemisphere: 28.91; Liver: 26.21; Brain - Substantia nigra: 24.15; Brain - Hippocampus: 19.41; Brain - Hypothalamus: 17.94; Brain - Putamen (basal ganglia): 14.90; Brain - Caudate (basal ganglia): 13.72; Brain - Amygdala: 12.79; Brain - Cortex: 12.24; Brain - Frontal Cortex (BA9): 11.28; Brain - Nucleus accumbens (basal ganglia): 11.27; Brain - Anterior cingulate cortex (BA24): 8.62; Cells - Transformed fibroblasts: 8.35; MESGAYGAAKAGGSFDLRRFLTQPQVVARAVCLVFALIVFSCIYGEGYSNAHESKQMYCVFNRNEDACRYGSAIGVLAFLASAFFLVVDAYFPQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAVTNPKDVLVGADSVRAAITFSFFSIFSWGVLASLAYQRYKAGVDDFIQNYVDPTPDPNTAYASYPGASVDNYQQPPFTQNAETTEGYQPPPVY CEP295NL CEP295 N-terminal-like protein C295L_HUMAN (Q96MC4-1) GO:0003824 (0.63) ! catalytic activity; GO:0016740 (0.50) ! transferase activity; GO:0036094 (0.45) ! small molecule binding; GO:1901981 (0.44) ! phosphatidylinositol phosphate binding; GO:0030234 (0.44) ! enzyme regulator activity; GO:0033218 (0.43) ! amide binding; GO:0030246 (0.43) ! carbohydrate binding; GO:0010485 (0.43) ! H4 histone acetyltransferase activity; GO:0008375 (0.43) ! acetylglucosaminyltransferase activity; GO:0016787 (0.21) ! hydrolase activity; GO:0017111 (0.20) ! nucleoside-triphosphatase activity; GO:0016887 (0.19) ! ATPase activity; GO:0003774 (0.16) ! motor activity; GO:0005198 (0.12) ! structural molecule activity; GO:0003777 (0.12) ! microtubule motor activity; GO:0016301 (0.11) ! kinase activity; GO:0008092 (0.10) ! cytoskeletal protein binding; GO:0004674 (0.10) ! protein serine/threonine kinase activity; GO:1901363 (0.08) ! heterocyclic compound binding; GO:0097159 (0.08) ! organic cyclic compound binding; GO:0022892 (0.08) ! substrate-specific transporter activity; GO:0022857 (0.08) ! transmembrane transporter activity; GO:0019899 (0.08) ! enzyme binding; GO:0032403 (0.07) ! protein complex binding; GO:0022891 (0.07) ! substrate-specific transmembrane transporter activity; GO:0042623 (0.06) ! ATPase activity, coupled; GO:0003779 (0.06) ! actin binding; GO:0097367 (0.05) ! carbohydrate derivative binding; GO:0051015 (0.05) ! actin filament binding; GO:0046873 (0.05) ! metal ion transmembrane transporter activity; GO:0022843 (0.05) ! voltage-gated cation channel activity; GO:0003676 (0.05) ! nucleic acid binding; GO:0046872 (0.04) ! metal ion binding; GO:0044822 (0.04) ! poly(A) RNA binding; GO:0030674 (0.04) ! protein binding, bridging; GO:0008331 (0.04) ! high voltage-gated calcium channel activity; GO:0008307 (0.04) ! structural constituent of muscle; GO:0005524 (0.04) ! ATP binding; GO:0004702 (0.04) ! receptor signaling protein serine/threonine kinase activity; GO:0000146 (0.04) ! microfilament motor activity; GO:0042802 (0.03) ! identical protein binding; GO:0019901 (0.03) ! protein kinase binding; GO:0017016 (0.03) ! Ras GTPase binding; GO:0005200 (0.03) ! structural constituent of cytoskeleton; GO:0097493 (0.02) ! structural molecule activity conferring elasticity; GO:0051371 (0.02) ! muscle alpha-actinin binding; GO:0042803 (0.02) ! protein homodimerization activity; GO:0030898 (0.02) ! actin-dependent ATPase activity; GO:0030506 (0.02) ! ankyrin binding; GO:0019904 (0.02) ! protein domain specific binding; GO:0017137 (0.02) ! Rab GTPase binding; GO:0017048 (0.02) ! Rho GTPase binding; GO:0015171 (0.02) ! amino acid transmembrane transporter activity; GO:0008094 (0.02) ! DNA-dependent ATPase activity; GO:0008022 (0.02) ! protein C-terminus binding; GO:0005516 (0.02) ! calmodulin binding; GO:0005509 (0.02) ! calcium ion binding; GO:0000287 (0.02) ! magnesium ion binding; GO:0098641 (0.01) ! cadherin binding involved in cell-cell adhesion; GO:0097110 (0.01) ! scaffold protein binding; GO:0070087 (0.01) ! chromo shadow domain binding; GO:0051011 (0.01) ! microtubule minus-end binding; GO:0047485 (0.01) ! protein N-terminus binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0044212 (0.01) ! transcription regulatory region DNA binding; GO:0043621 (0.01) ! protein self-association; GO:0043531 (0.01) ! ADP binding; GO:0043141 (0.01) ! ATP-dependent 5'-3' DNA helicase activity; GO:0043130 (0.01) ! ubiquitin binding; GO:0043015 (0.01) ! gamma-tubulin binding; GO:0042826 (0.01) ! histone deacetylase binding; GO:0031433 (0.01) ! telethonin binding; GO:0030507 (0.01) ! spectrin binding; GO:0030165 (0.01) ! PDZ domain binding; GO:0019905 (0.01) ! syntaxin binding; GO:0019902 (0.01) ! phosphatase binding; GO:0019894 (0.01) ! kinesin binding; GO:0010521 (0.01) ! telomerase inhibitor activity; GO:0008574 (0.01) ! ATP-dependent microtubule motor activity, plus-end-directed; GO:0008565 (0.01) ! protein transporter activity; GO:0008093 (0.01) ! cytoskeletal adaptor activity; GO:0008047 (0.01) ! enzyme activator activity; GO:0005267 (0.01) ! potassium channel activity; GO:0005102 (0.01) ! receptor binding; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0005080 (0.01) ! protein kinase C binding; GO:0004842 (0.01) ! ubiquitin-protein transferase activity; GO:0004713 (0.01) ! protein tyrosine kinase activity; GO:0004687 (0.01) ! myosin light chain kinase activity; GO:0004683 (0.01) ! calmodulin-dependent protein kinase activity; GO:0004367 (0.01) ! glycerol-3-phosphate dehydrogenase [NAD+] activity; GO:0004004 (0.01) ! ATP-dependent RNA helicase activity; GO:0003700 (0.01) ! transcription factor activity, sequence-specific DNA binding; GO:0002020 (0.01) ! protease binding GO:0065007 (0.75) ! biological regulation; GO:0050789 (0.72) ! regulation of biological process; GO:0009987 (0.72) ! cellular process; GO:0050794 (0.71) ! regulation of cellular process; GO:0044699 (0.67) ! single-organism process; GO:0044763 (0.65) ! single-organism cellular process; GO:0051128 (0.64) ! regulation of cellular component organization; GO:0048518 (0.63) ! positive regulation of biological process; GO:0048522 (0.62) ! positive regulation of cellular process; GO:0033043 (0.61) ! regulation of organelle organization; GO:0010638 (0.58) ! positive regulation of organelle organization; GO:0016043 (0.55) ! cellular component organization; GO:0032502 (0.51) ! developmental process; GO:0044767 (0.49) ! single-organism developmental process; GO:0051179 (0.48) ! localization; GO:0006996 (0.48) ! organelle organization; GO:0071704 (0.47) ! organic substance metabolic process; GO:0048856 (0.47) ! anatomical structure development; GO:0044260 (0.46) ! cellular macromolecule metabolic process; GO:0044238 (0.46) ! primary metabolic process; GO:0065008 (0.44) ! regulation of biological quality; GO:0051641 (0.44) ! cellular localization; GO:0022607 (0.44) ! cellular component assembly; GO:0044267 (0.43) ! cellular protein metabolic process; GO:0080090 (0.42) ! regulation of primary metabolic process; GO:0050896 (0.42) ! response to stimulus; GO:0031323 (0.42) ! regulation of cellular metabolic process; GO:0006464 (0.42) ! cellular protein modification process; GO:0060255 (0.41) ! regulation of macromolecule metabolic process; GO:0051239 (0.41) ! regulation of multicellular organismal process; GO:0050793 (0.41) ! regulation of developmental process; GO:0048523 (0.41) ! negative regulation of cellular process; GO:0048513 (0.41) ! animal organ development; GO:0043933 (0.41) ! macromolecular complex subunit organization; GO:0032879 (0.41) ! regulation of localization; GO:0016310 (0.41) ! phosphorylation; GO:2000026 (0.40) ! regulation of multicellular organismal development; GO:0010468 (0.40) ! regulation of gene expression; GO:0051716 (0.39) ! cellular response to stimulus; GO:0051640 (0.39) ! organelle localization; GO:0051049 (0.39) ! regulation of transport; GO:0048583 (0.39) ! regulation of response to stimulus; GO:0032880 (0.39) ! regulation of protein localization; GO:0032270 (0.39) ! positive regulation of cellular protein metabolic process; GO:0031399 (0.39) ! regulation of protein modification process; GO:0031324 (0.39) ! negative regulation of cellular metabolic process; GO:0023051 (0.39) ! regulation of signaling; GO:0010646 (0.39) ! regulation of cell communication; GO:0010605 (0.39) ! negative regulation of macromolecule metabolic process; GO:0009605 (0.39) ! response to external stimulus; GO:0007165 (0.39) ! signal transduction; GO:0006461 (0.39) ! protein complex assembly; GO:0006357 (0.39) ! regulation of transcription from RNA polymerase II promoter; GO:0006139 (0.39) ! nucleobase-containing compound metabolic process; GO:1902531 (0.38) ! regulation of intracellular signal transduction; GO:0065009 (0.38) ! regulation of molecular function; GO:0060341 (0.38) ! regulation of cellular localization; GO:0051240 (0.38) ! positive regulation of multicellular organismal process; GO:0051129 (0.38) ! negative regulation of cellular component organization; GO:0051094 (0.38) ! positive regulation of developmental process; GO:0045595 (0.38) ! regulation of cell differentiation; GO:0043207 (0.38) ! response to external biotic stimulus; GO:0042221 (0.38) ! response to chemical; GO:0033044 (0.38) ! regulation of chromosome organization; GO:0032535 (0.38) ! regulation of cellular component size; GO:0031401 (0.38) ! positive regulation of protein modification process; GO:0010628 (0.38) ! positive regulation of gene expression; GO:0007166 (0.38) ! cell surface receptor signaling pathway; GO:0006325 (0.38) ! chromatin organization; GO:0001932 (0.38) ! regulation of protein phosphorylation; GO:2000379 (0.37) ! positive regulation of reactive oxygen species metabolic process; GO:1903829 (0.37) ! positive regulation of cellular protein localization; GO:1903578 (0.37) ! regulation of ATP metabolic process; GO:1903426 (0.37) ! regulation of reactive oxygen species biosynthetic process; GO:1903321 (0.37) ! negative regulation of protein modification by small protein conjugation or removal; GO:1901071 (0.37) ! glucosamine-containing compound metabolic process; GO:1900180 (0.37) ! regulation of protein localization to nucleus; GO:1900076 (0.37) ! regulation of cellular response to insulin stimulus; GO:1900037 (0.37) ! regulation of cellular response to hypoxia; GO:0090317 (0.37) ! negative regulation of intracellular protein transport; GO:0090313 (0.37) ! regulation of protein targeting to membrane; GO:0071396 (0.37) ! cellular response to lipid; GO:0071331 (0.37) ! cellular response to hexose stimulus; GO:0071229 (0.37) ! cellular response to acid chemical; GO:0071219 (0.37) ! cellular response to molecule of bacterial origin; GO:0070206 (0.37) ! protein trimerization; GO:0061085 (0.37) ! regulation of histone H3-K27 methylation; GO:0051569 (0.37) ! regulation of histone H3-K4 methylation; GO:0051291 (0.37) ! protein heterooligomerization; GO:0051260 (0.37) ! protein homooligomerization; GO:0051196 (0.37) ! regulation of coenzyme metabolic process; GO:0050790 (0.37) ! regulation of catalytic activity; GO:0048585 (0.37) ! negative regulation of response to stimulus; GO:0048311 (0.37) ! mitochondrion distribution; GO:0048017 (0.37) ! inositol lipid-mediated signaling; GO:0046578 (0.37) ! regulation of Ras protein signal transduction; GO:0045893 (0.37) ! positive regulation of transcription, DNA-templated; GO:0044093 (0.37) ! positive regulation of molecular function; GO:0043967 (0.37) ! histone H4 acetylation; GO:0043470 (0.37) ! regulation of carbohydrate catabolic process; GO:0043467 (0.37) ! regulation of generation of precursor metabolites and energy; GO:0042327 (0.37) ! positive regulation of phosphorylation; GO:0033135 (0.37) ! regulation of peptidyl-serine phosphorylation; GO:0032526 (0.37) ! response to retinoic acid; GO:0032496 (0.37) ! response to lipopolysaccharide; GO:0031667 (0.37) ! response to nutrient levels; GO:0031396 (0.37) ! regulation of protein ubiquitination; GO:0031062 (0.37) ! positive regulation of histone methylation; GO:0030852 (0.37) ! regulation of granulocyte differentiation; GO:0030162 (0.37) ! regulation of proteolysis; GO:0018023 (0.37) ! peptidyl-lysine trimethylation; GO:0016601 (0.37) ! Rac protein signal transduction; GO:0012501 (0.37) ! programmed cell death; GO:0010941 (0.37) ! regulation of cell death; GO:0010799 (0.37) ! regulation of peptidyl-threonine phosphorylation; GO:0009749 (0.37) ! response to glucose; GO:0009636 (0.37) ! response to toxic substance; GO:0008361 (0.37) ! regulation of cell size; GO:0008286 (0.37) ! insulin receptor signaling pathway; GO:0007623 (0.37) ! circadian rhythm; GO:0007420 (0.37) ! brain development; GO:0006486 (0.37) ! protein glycosylation; GO:0006111 (0.37) ! regulation of gluconeogenesis; GO:0006096 (0.37) ! glycolytic process; GO:0002763 (0.37) ! positive regulation of myeloid leukocyte differentiation; GO:0001933 (0.37) ! negative regulation of protein phosphorylation; GO:0001678 (0.37) ! cellular glucose homeostasis; GO:0044087 (0.35) ! regulation of cellular component biogenesis; GO:1902115 (0.33) ! regulation of organelle assembly; GO:1902117 (0.32) ! positive regulation of organelle assembly; GO:0006928 (0.19) ! movement of cell or subcellular component; GO:0051234 (0.16) ! establishment of localization; GO:0048869 (0.16) ! cellular developmental process; GO:0006810 (0.15) ! transport; GO:1902589 (0.14) ! single-organism organelle organization; GO:0007017 (0.13) ! microtubule-based process; GO:0007010 (0.13) ! cytoskeleton organization; GO:0030029 (0.12) ! actin filament-based process; GO:0009653 (0.11) ! anatomical structure morphogenesis; GO:0007018 (0.11) ! microtubule-based movement; GO:0032501 (0.10) ! multicellular organismal process; GO:0030036 (0.10) ! actin cytoskeleton organization; GO:0051649 (0.09) ! establishment of localization in cell; GO:0031032 (0.09) ! actomyosin structure organization; GO:0048646 (0.08) ! anatomical structure formation involved in morphogenesis; GO:0016192 (0.08) ! vesicle-mediated transport; GO:0003008 (0.08) ! system process; GO:1902578 (0.07) ! single-organism localization; GO:0046907 (0.07) ! intracellular transport; GO:0040011 (0.07) ! locomotion; GO:0030154 (0.07) ! cell differentiation; GO:0022414 (0.07) ! reproductive process; GO:0071702 (0.06) ! organic substance transport; GO:0070925 (0.06) ! organelle assembly; GO:0044765 (0.06) ! single-organism transport; GO:0030705 (0.06) ! cytoskeleton-dependent intracellular transport; GO:0030030 (0.06) ! cell projection organization; GO:0022402 (0.06) ! cell cycle process; GO:0010927 (0.06) ! cellular component assembly involved in morphogenesis; GO:0006468 (0.06) ! protein phosphorylation; GO:1903047 (0.05) ! mitotic cell cycle process; GO:0051726 (0.05) ! regulation of cell cycle; GO:0048468 (0.05) ! cell development; GO:0044707 (0.05) ! single-multicellular organism process; GO:0044702 (0.05) ! single organism reproductive process; GO:0042391 (0.05) ! regulation of membrane potential; GO:0016477 (0.05) ! cell migration; GO:0008104 (0.05) ! protein localization; GO:0090304 (0.04) ! nucleic acid metabolic process; GO:0061024 (0.04) ! membrane organization; GO:0051493 (0.04) ! regulation of cytoskeleton organization; GO:0045214 (0.04) ! sarcomere organization; GO:0043623 (0.04) ! cellular protein complex assembly; GO:0032989 (0.04) ! cellular component morphogenesis; GO:0032970 (0.04) ! regulation of actin filament-based process; GO:0030239 (0.04) ! myofibril assembly; GO:0010564 (0.04) ! regulation of cell cycle process; GO:0009888 (0.04) ! tissue development; GO:0009628 (0.04) ! response to abiotic stimulus; GO:0007610 (0.04) ! behavior; GO:0007015 (0.04) ! actin filament organization; GO:0006950 (0.04) ! response to stress; GO:2000113 (0.03) ! negative regulation of cellular macromolecule biosynthetic process; GO:1902580 (0.03) ! single-organism cellular localization; GO:0086010 (0.03) ! membrane depolarization during action potential; GO:0071705 (0.03) ! nitrogen compound transport; GO:0071688 (0.03) ! striated muscle myosin thick filament assembly; GO:0055085 (0.03) ! transmembrane transport; GO:0051960 (0.03) ! regulation of nervous system development; GO:0051704 (0.03) ! multi-organism process; GO:0050890 (0.03) ! cognition; GO:0048858 (0.03) ! cell projection morphogenesis; GO:0048729 (0.03) ! tissue morphogenesis; GO:0048638 (0.03) ! regulation of developmental growth; GO:0045934 (0.03) ! negative regulation of nucleobase-containing compound metabolic process; GO:0035107 (0.03) ! appendage morphogenesis; GO:0034613 (0.03) ! cellular protein localization; GO:0033554 (0.03) ! cellular response to stress; GO:0032886 (0.03) ! regulation of microtubule-based process; GO:0031175 (0.03) ! neuron projection development; GO:0030855 (0.03) ! epithelial cell differentiation; GO:0022603 (0.03) ! regulation of anatomical structure morphogenesis; GO:0022412 (0.03) ! cellular process involved in reproduction in multicellular organism; GO:0015031 (0.03) ! protein transport; GO:0007626 (0.03) ! locomotory behavior; GO:0007519 (0.03) ! skeletal muscle tissue development; GO:0007389 (0.03) ! pattern specification process; GO:0006936 (0.03) ! muscle contraction; GO:0001667 (0.03) ! ameboidal-type cell migration; GO:0000910 (0.03) ! cytokinesis; GO:0000226 (0.03) ! microtubule cytoskeleton organization; GO:1903046 (0.02) ! meiotic cell cycle process; GO:1902685 (0.02) ! positive regulation of receptor localization to synapse; GO:1902582 (0.02) ! single-organism intracellular transport; GO:1901576 (0.02) ! organic substance biosynthetic process; GO:0061564 (0.02) ! axon development; GO:0060271 (0.02) ! cilium morphogenesis; GO:0055008 (0.02) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.02) ! cardiac myofibril assembly; GO:0051656 (0.02) ! establishment of organelle localization; GO:0051276 (0.02) ! chromosome organization; GO:0051270 (0.02) ! regulation of cellular component movement; GO:0048739 (0.02) ! cardiac muscle fiber development; GO:0048598 (0.02) ! embryonic morphogenesis; GO:0048589 (0.02) ! developmental growth; GO:0046622 (0.02) ! positive regulation of organ growth; GO:0045109 (0.02) ! intermediate filament organization; GO:0044802 (0.02) ! single-organism membrane organization; GO:0044772 (0.02) ! mitotic cell cycle phase transition; GO:0044249 (0.02) ! cellular biosynthetic process; GO:0034330 (0.02) ! cell junction organization; GO:0032956 (0.02) ! regulation of actin cytoskeleton organization; GO:0032940 (0.02) ! secretion by cell; GO:0032465 (0.02) ! regulation of cytokinesis; GO:0031532 (0.02) ! actin cytoskeleton reorganization; GO:0030431 (0.02) ! sleep; GO:0030241 (0.02) ! skeletal muscle myosin thick filament assembly; GO:0030240 (0.02) ! skeletal muscle thin filament assembly; GO:0030216 (0.02) ! keratinocyte differentiation; GO:0030048 (0.02) ! actin filament-based movement; GO:0022604 (0.02) ! regulation of cell morphogenesis; GO:0022008 (0.02) ! neurogenesis; GO:0019730 (0.02) ! antimicrobial humoral response; GO:0018149 (0.02) ! peptide cross-linking; GO:0016322 (0.02) ! neuron remodeling; GO:0010824 (0.02) ! regulation of centrosome duplication; GO:0010224 (0.02) ! response to UV-B; GO:0009887 (0.02) ! organ morphogenesis; GO:0008582 (0.02) ! regulation of synaptic growth at neuromuscular junction; GO:0008340 (0.02) ! determination of adult lifespan; GO:0008016 (0.02) ! regulation of heart contraction; GO:0007614 (0.02) ! short-term memory; GO:0007600 (0.02) ! sensory perception; GO:0007476 (0.02) ! imaginal disc-derived wing morphogenesis; GO:0007411 (0.02) ! axon guidance; GO:0007379 (0.02) ! segment specification; GO:0007350 (0.02) ! blastoderm segmentation; GO:0007298 (0.02) ! border follicle cell migration; GO:0007059 (0.02) ! chromosome segregation; GO:0006974 (0.02) ! cellular response to DNA damage stimulus; GO:0006941 (0.02) ! striated muscle contraction; GO:0006886 (0.02) ! intracellular protein transport; GO:0006396 (0.02) ! RNA processing; GO:0006259 (0.02) ! DNA metabolic process; GO:0003333 (0.02) ! amino acid transmembrane transport; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0002064 (0.02) ! epithelial cell development; GO:0000122 (0.02) ! negative regulation of transcription from RNA polymerase II promoter; GO:2000431 (0.01) ! regulation of cytokinesis, actomyosin contractile ring assembly; GO:2000027 (0.01) ! regulation of organ morphogenesis; GO:1903923 (0.01) ! positive regulation of protein processing in phagocytic vesicle; GO:1903919 (0.01) ! negative regulation of actin filament severing; GO:1902513 (0.01) ! regulation of organelle transport along microtubule; GO:0098911 (0.01) ! regulation of ventricular cardiac muscle cell action potential; GO:0090316 (0.01) ! positive regulation of intracellular protein transport; GO:0090307 (0.01) ! mitotic spindle assembly; GO:0090164 (0.01) ! asymmetric Golgi ribbon formation; GO:0086091 (0.01) ! regulation of heart rate by cardiac conduction; GO:0086073 (0.01) ! bundle of His cell-Purkinje myocyte adhesion involved in cell communication; GO:0072659 (0.01) ! protein localization to plasma membrane; GO:0072104 (0.01) ! glomerular capillary formation; GO:0072015 (0.01) ! glomerular visceral epithelial cell development; GO:0071896 (0.01) ! protein localization to adherens junction; GO:0071689 (0.01) ! muscle thin filament assembly; GO:0071214 (0.01) ! cellular response to abiotic stimulus; GO:0061025 (0.01) ! membrane fusion; GO:0060627 (0.01) ! regulation of vesicle-mediated transport; GO:0060048 (0.01) ! cardiac muscle contraction; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0051974 (0.01) ! negative regulation of telomerase activity; GO:0051924 (0.01) ! regulation of calcium ion transport; GO:0051701 (0.01) ! interaction with host; GO:0051592 (0.01) ! response to calcium ion; GO:0051415 (0.01) ! interphase microtubule nucleation by interphase microtubule organizing center; GO:0051298 (0.01) ! centrosome duplication; GO:0050714 (0.01) ! positive regulation of protein secretion; GO:0048769 (0.01) ! sarcomerogenesis; GO:0048731 (0.01) ! system development; GO:0048699 (0.01) ! generation of neurons; GO:0048666 (0.01) ! neuron development; GO:0048477 (0.01) ! oogenesis; GO:0048211 (0.01) ! Golgi vesicle docking; GO:0048194 (0.01) ! Golgi vesicle budding; GO:0045944 (0.01) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045859 (0.01) ! regulation of protein kinase activity; GO:0045056 (0.01) ! transcytosis; GO:0044806 (0.01) ! G-quadruplex DNA unwinding; GO:0044248 (0.01) ! cellular catabolic process; GO:0043588 (0.01) ! skin development; GO:0043473 (0.01) ! pigmentation; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0042476 (0.01) ! odontogenesis; GO:0042060 (0.01) ! wound healing; GO:0035995 (0.01) ! detection of muscle stretch; GO:0035113 (0.01) ! embryonic appendage morphogenesis; GO:0035082 (0.01) ! axoneme assembly; GO:0035058 (0.01) ! nonmotile primary cilium assembly; GO:0034088 (0.01) ! maintenance of mitotic sister chromatid cohesion; GO:0033693 (0.01) ! neurofilament bundle assembly; GO:0033365 (0.01) ! protein localization to organelle; GO:0032869 (0.01) ! cellular response to insulin stimulus; GO:0032836 (0.01) ! glomerular basement membrane development; GO:0032835 (0.01) ! glomerulus development; GO:0032774 (0.01) ! RNA biosynthetic process; GO:0032508 (0.01) ! DNA duplex unwinding; GO:0032467 (0.01) ! positive regulation of cytokinesis; GO:0032439 (0.01) ! endosome localization; GO:0032252 (0.01) ! secretory granule localization; GO:0032211 (0.01) ! negative regulation of telomere maintenance via telomerase; GO:0031581 (0.01) ! hemidesmosome assembly; GO:0031503 (0.01) ! protein complex localization; GO:0031297 (0.01) ! replication fork processing; GO:0031122 (0.01) ! cytoplasmic microtubule organization; GO:0031100 (0.01) ! organ regeneration; GO:0030050 (0.01) ! vesicle transport along actin filament; GO:0016567 (0.01) ! protein ubiquitination; GO:0014866 (0.01) ! skeletal myofibril assembly; GO:0014070 (0.01) ! response to organic cyclic compound; GO:0010977 (0.01) ! negative regulation of neuron projection development; GO:0010970 (0.01) ! establishment of localization by movement along microtubule; GO:0010817 (0.01) ! regulation of hormone levels; GO:0010457 (0.01) ! centriole-centriole cohesion; GO:0009967 (0.01) ! positive regulation of signal transduction; GO:0009792 (0.01) ! embryo development ending in birth or egg hatching; GO:0009057 (0.01) ! macromolecule catabolic process; GO:0008360 (0.01) ! regulation of cell shape; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008217 (0.01) ! regulation of blood pressure; GO:0008064 (0.01) ! regulation of actin polymerization or depolymerization; GO:0007601 (0.01) ! visual perception; GO:0007528 (0.01) ! neuromuscular junction development; GO:0007507 (0.01) ! heart development; GO:0007498 (0.01) ! mesoderm development; GO:0007419 (0.01) ! ventral cord development; GO:0007409 (0.01) ! axonogenesis; GO:0007283 (0.01) ! spermatogenesis; GO:0007269 (0.01) ! neurotransmitter secretion; GO:0007268 (0.01) ! chemical synaptic transmission; GO:0007204 (0.01) ! positive regulation of cytosolic calcium ion concentration; GO:0007163 (0.01) ! establishment or maintenance of cell polarity; GO:0007126 (0.01) ! meiotic nuclear division; GO:0007112 (0.01) ! male meiosis cytokinesis; GO:0007091 (0.01) ! metaphase/anaphase transition of mitotic cell cycle; GO:0007067 (0.01) ! mitotic nuclear division; GO:0006997 (0.01) ! nucleus organization; GO:0006911 (0.01) ! phagocytosis, engulfment; GO:0006897 (0.01) ! endocytosis; GO:0006892 (0.01) ! post-Golgi vesicle-mediated transport; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006887 (0.01) ! exocytosis; GO:0006816 (0.01) ! calcium ion transport; GO:0006397 (0.01) ! mRNA processing; GO:0006364 (0.01) ! rRNA processing; GO:0006338 (0.01) ! chromatin remodeling; GO:0006260 (0.01) ! DNA replication; GO:0006072 (0.01) ! glycerol-3-phosphate metabolic process; GO:0003300 (0.01) ! cardiac muscle hypertrophy; GO:0003223 (0.01) ! ventricular compact myocardium morphogenesis; GO:0003094 (0.01) ! glomerular filtration; GO:0003007 (0.01) ! heart morphogenesis; GO:0002934 (0.01) ! desmosome organization; GO:0002009 (0.01) ! morphogenesis of an epithelium; GO:0001934 (0.01) ! positive regulation of protein phosphorylation; GO:0001558 (0.01) ! regulation of cell growth; GO:0000915 (0.01) ! actomyosin contractile ring assembly; GO:0000904 (0.01) ! cell morphogenesis involved in differentiation; GO:0000281 (0.01) ! mitotic cytokinesis; GO:0000278 (0.01) ! mitotic cell cycle; GO:0000086 (0.01) ! G2/M transition of mitotic cell cycle; GO:0000002 (0.01) ! mitochondrial genome maintenance GO:0044464 (1.00) ! cell part; GO:0044424 (0.97) ! intracellular part; GO:0044444 (0.83) ! cytoplasmic part; GO:0043226 (0.83) ! organelle; GO:0044422 (0.81) ! organelle part; GO:0044446 (0.80) ! intracellular organelle part; GO:0043229 (0.74) ! intracellular organelle; GO:0043234 (0.63) ! protein complex; GO:0043227 (0.59) ! membrane-bounded organelle; GO:0044430 (0.58) ! cytoskeletal part; GO:0043231 (0.57) ! intracellular membrane-bounded organelle; GO:0005737 (0.53) ! cytoplasm; GO:0016020 (0.44) ! membrane; GO:0005829 (0.43) ! cytosol; GO:0043232 (0.42) ! intracellular non-membrane-bounded organelle; GO:0044428 (0.33) ! nuclear part; GO:0005634 (0.33) ! nucleus; GO:0044450 (0.30) ! microtubule organizing center part; GO:1990234 (0.28) ! transferase complex; GO:0042995 (0.28) ! cell projection; GO:0005814 (0.28) ! centriole; GO:0005813 (0.27) ! centrosome; GO:0005886 (0.25) ! plasma membrane; GO:0005856 (0.25) ! cytoskeleton; GO:0005654 (0.25) ! nucleoplasm; GO:0044425 (0.22) ! membrane part; GO:0005739 (0.20) ! mitochondrion; GO:0031988 (0.18) ! membrane-bounded vesicle; GO:0005929 (0.16) ! cilium; GO:0000151 (0.16) ! ubiquitin ligase complex; GO:0031514 (0.15) ! motile cilium; GO:0005680 (0.15) ! anaphase-promoting complex; GO:0031090 (0.13) ! organelle membrane; GO:0098805 (0.12) ! whole membrane; GO:0098588 (0.12) ! bounding membrane of organelle; GO:0016021 (0.12) ! integral component of membrane; GO:0005875 (0.12) ! microtubule associated complex; GO:0000785 (0.12) ! chromatin; GO:0097458 (0.11) ! neuron part; GO:0070062 (0.11) ! extracellular exosome; GO:0031307 (0.11) ! integral component of mitochondrial outer membrane; GO:0031248 (0.11) ! protein acetyltransferase complex; GO:0005741 (0.11) ! mitochondrial outer membrane; GO:0043025 (0.10) ! neuronal cell body; GO:0043005 (0.09) ! neuron projection; GO:0031410 (0.09) ! cytoplasmic vesicle; GO:0005871 (0.09) ! kinesin complex; GO:0098796 (0.08) ! membrane protein complex; GO:0030141 (0.08) ! secretory granule; GO:0070688 (0.07) ! MLL5-L complex; GO:0044463 (0.07) ! cell projection part; GO:0044459 (0.07) ! plasma membrane part; GO:0042588 (0.07) ! zymogen granule; GO:0000791 (0.07) ! euchromatin; GO:0000123 (0.07) ! histone acetyltransferase complex; GO:0099513 (0.06) ! polymeric cytoskeletal fiber; GO:0044449 (0.06) ! contractile fiber part; GO:0098590 (0.05) ! plasma membrane region; GO:0016459 (0.05) ! myosin complex; GO:0015629 (0.05) ! actin cytoskeleton; GO:0005783 (0.05) ! endoplasmic reticulum; GO:0055087 (0.04) ! Ski complex; GO:0045177 (0.04) ! apical part of cell; GO:0032587 (0.04) ! ruffle membrane; GO:0031618 (0.04) ! nuclear pericentric heterochromatin; GO:0031416 (0.04) ! NatB complex; GO:0031415 (0.04) ! NatA complex; GO:0031205 (0.04) ! endoplasmic reticulum Sec complex; GO:0030992 (0.04) ! intraciliary transport particle B; GO:0030054 (0.04) ! cell junction; GO:0005876 (0.04) ! spindle microtubule; GO:0005819 (0.04) ! spindle; GO:0005790 (0.04) ! smooth endoplasmic reticulum; GO:0005788 (0.04) ! endoplasmic reticulum lumen; GO:0005742 (0.04) ! mitochondrial outer membrane translocase complex; GO:0005622 (0.04) ! intracellular; GO:0000127 (0.04) ! transcription factor TFIIIC complex; GO:0044448 (0.03) ! cell cortex part; GO:0030018 (0.03) ! Z disc; GO:0030017 (0.03) ! sarcomere; GO:0016460 (0.03) ! myosin II complex; GO:0005911 (0.03) ! cell-cell junction; GO:0098791 (0.02) ! Golgi subcompartment; GO:0042641 (0.02) ! actomyosin; GO:0034451 (0.02) ! centriolar satellite; GO:0032155 (0.02) ! cell division site part; GO:0031674 (0.02) ! I band; GO:0031430 (0.02) ! M band; GO:0031252 (0.02) ! cell leading edge; GO:0005938 (0.02) ! cell cortex; GO:0005925 (0.02) ! focal adhesion; GO:0005882 (0.02) ! intermediate filament; GO:0005865 (0.02) ! striated muscle thin filament; GO:0005859 (0.02) ! muscle myosin complex; GO:0001533 (0.02) ! cornified envelope; GO:0055037 (0.01) ! recycling endosome; GO:0048471 (0.01) ! perinuclear region of cytoplasm; GO:0045179 (0.01) ! apical cortex; GO:0045111 (0.01) ! intermediate filament cytoskeleton; GO:0044456 (0.01) ! synapse part; GO:0043292 (0.01) ! contractile fiber; GO:0043256 (0.01) ! laminin complex; GO:0043034 (0.01) ! costamere; GO:0042383 (0.01) ! sarcolemma; GO:0034399 (0.01) ! nuclear periphery; GO:0033267 (0.01) ! axon part; GO:0032593 (0.01) ! insulin-responsive compartment; GO:0032154 (0.01) ! cleavage furrow; GO:0032116 (0.01) ! SMC loading complex; GO:0031985 (0.01) ! Golgi cisterna; GO:0031965 (0.01) ! nuclear membrane; GO:0031672 (0.01) ! A band; GO:0031012 (0.01) ! extracellular matrix; GO:0030529 (0.01) ! intracellular ribonucleoprotein complex; GO:0030496 (0.01) ! midbody; GO:0030425 (0.01) ! dendrite; GO:0030424 (0.01) ! axon; GO:0030057 (0.01) ! desmosome; GO:0030056 (0.01) ! hemidesmosome; GO:0016528 (0.01) ! sarcoplasm; GO:0015630 (0.01) ! microtubule cytoskeleton; GO:0014704 (0.01) ! intercalated disc; GO:0012507 (0.01) ! ER to Golgi transport vesicle membrane; GO:0008274 (0.01) ! gamma-tubulin ring complex; GO:0005930 (0.01) ! axoneme; GO:0005913 (0.01) ! cell-cell adherens junction; GO:0005903 (0.01) ! brush border; GO:0005891 (0.01) ! voltage-gated calcium channel complex; GO:0005887 (0.01) ! integral component of plasma membrane; GO:0005826 (0.01) ! actomyosin contractile ring; GO:0005816 (0.01) ! spindle pole body; GO:0005802 (0.01) ! trans-Golgi network; GO:0005795 (0.01) ! Golgi stack; GO:0005794 (0.01) ! Golgi apparatus; GO:0005730 (0.01) ! nucleolus; GO:0005657 (0.01) ! replication fork; GO:0005615 (0.01) ! extracellular space; GO:0005604 (0.01) ! basement membrane; GO:0005576 (0.01) ! extracellular region; GO:0001726 (0.01) ! ruffle; GO:0000923 (0.01) ! equatorial microtubule organizing center; GO:0000922 (0.01) ! spindle pole; GO:0000347 (0.01) ! THO complex; GO:0000228 (0.01) ! nuclear chromosome GO:0005929 ! cilium; GO:0042995 ! cell projection 2 78870910-78903217 (17q25.3) MCSGWSSSVIWRHTQFAVERCGFCGSSGPGAPLEPSTLGSKHLPWEAVSAGFADRNRNMDGAMWLSLCPDNEDLLWRKKHKLLQARGKGDLALQRRADAKLWKNYQLQRLAEELRRGYQEAQHLHVGGLDRLQSARLLGWGGGRARENEPDSQGPIQRRSARPPRAKEKHRAALSEERSCREELGQQHPRHSRPRKTAASPEKPQTTKATGRMNSHLAPPEKRKGRPEPSTKSGGGRCAIHPRRSKGADLERSNPLVAAVGEIGLVEEKEKGTARAGRRQLGKGAVCFVPALTSRSQGQSLEGKLRDLGQLWPADSSCRREAVSPASQCTLREKNKWQKELELAFEELFNINRKLKKHLCLYLALKPRMDQRPGEGHAFSEMQECGAGTPRGKKMADPEMLPAGEPRSPAEEEAQQAASKTDLKTFMGKAQNQKYQGTVKPTFRNGSQTLSPEAGIFINKEDSLLYSTESGQETPKLGTLAEGSLQLHLQDQADRVGSTASRQRQKAEMEQRRQKQLESLEQMEHPDMSLEIHYKAELEKERREQRRARLAHLKSSSTRAQERERGSELSTTSPSGTSLADDDRHSQMIRDQQQQILQQNRLHKQFLEEARKCLREFQNIC TEPSIN AP-4 complex accessory subunit Tepsin AP4AT_HUMAN (Q96N21-1) GO:0003824 (0.47) ! catalytic activity; GO:0043167 (0.43) ! ion binding; GO:0043169 (0.42) ! cation binding; GO:0016740 (0.15) ! transferase activity; GO:0016787 (0.11) ! hydrolase activity; GO:0005198 (0.11) ! structural molecule activity; GO:1901363 (0.10) ! heterocyclic compound binding; GO:0097159 (0.10) ! organic cyclic compound binding; GO:0016772 (0.09) ! transferase activity, transferring phosphorus-containing groups; GO:0044877 (0.08) ! macromolecular complex binding; GO:0003676 (0.08) ! nucleic acid binding; GO:0098772 (0.07) ! molecular function regulator; GO:0005215 (0.07) ! transporter activity; GO:0004872 (0.07) ! receptor activity; GO:0001104 (0.07) ! RNA polymerase II transcription cofactor activity; GO:0032403 (0.06) ! protein complex binding; GO:0005261 (0.06) ! cation channel activity; GO:0005201 (0.06) ! extracellular matrix structural constituent; GO:0004871 (0.06) ! signal transducer activity; GO:0004672 (0.06) ! protein kinase activity; GO:0099600 (0.05) ! transmembrane receptor activity; GO:0046873 (0.05) ! metal ion transmembrane transporter activity; GO:0019899 (0.05) ! enzyme binding; GO:0016788 (0.05) ! hydrolase activity, acting on ester bonds; GO:0008092 (0.05) ! cytoskeletal protein binding; GO:0005543 (0.05) ! phospholipid binding; GO:0030276 (0.04) ! clathrin binding; GO:0030234 (0.04) ! enzyme regulator activity; GO:0022836 (0.04) ! gated channel activity; GO:0017111 (0.04) ! nucleoside-triphosphatase activity; GO:0005102 (0.04) ! receptor binding; GO:0004888 (0.04) ! transmembrane signaling receptor activity; GO:0004842 (0.04) ! ubiquitin-protein transferase activity; GO:0004674 (0.04) ! protein serine/threonine kinase activity; GO:0003779 (0.04) ! actin binding; GO:0003723 (0.04) ! RNA binding; GO:0003682 (0.04) ! chromatin binding; GO:0003677 (0.04) ! DNA binding; GO:0051015 (0.03) ! actin filament binding; GO:0050839 (0.03) ! cell adhesion molecule binding; GO:0044822 (0.03) ! poly(A) RNA binding; GO:0022843 (0.03) ! voltage-gated cation channel activity; GO:0016887 (0.03) ! ATPase activity; GO:0015079 (0.03) ! potassium ion transmembrane transporter activity; GO:0008134 (0.03) ! transcription factor binding; GO:0005509 (0.03) ! calcium ion binding; GO:0005262 (0.03) ! calcium channel activity; GO:0005096 (0.03) ! GTPase activator activity; GO:0003777 (0.03) ! microtubule motor activity; GO:0003700 (0.03) ! transcription factor activity, sequence-specific DNA binding; GO:0001055 (0.03) ! RNA polymerase II activity; GO:1901981 (0.02) ! phosphatidylinositol phosphate binding; GO:0098641 (0.02) ! cadherin binding involved in cell-cell adhesion; GO:0097367 (0.02) ! carbohydrate derivative binding; GO:0070011 (0.02) ! peptidase activity, acting on L-amino acid peptides; GO:0052689 (0.02) ! carboxylic ester hydrolase activity; GO:0046983 (0.02) ! protein dimerization activity; GO:0044212 (0.02) ! transcription regulatory region DNA binding; GO:0042802 (0.02) ! identical protein binding; GO:0031491 (0.02) ! nucleosome binding; GO:0019904 (0.02) ! protein domain specific binding; GO:0019901 (0.02) ! protein kinase binding; GO:0017154 (0.02) ! semaphorin receptor activity; GO:0016298 (0.02) ! lipase activity; GO:0008307 (0.02) ! structural constituent of muscle; GO:0005544 (0.02) ! calcium-dependent phospholipid binding; GO:0005249 (0.02) ! voltage-gated potassium channel activity; GO:0005088 (0.02) ! Ras guanyl-nucleotide exchange factor activity; GO:0004713 (0.02) ! protein tyrosine kinase activity; GO:0000981 (0.02) ! RNA polymerase II transcription factor activity, sequence-specific DNA binding; GO:1990175 (0.01) ! EH domain binding; GO:0097493 (0.01) ! structural molecule activity conferring elasticity; GO:0071889 (0.01) ! 14-3-3 protein binding; GO:0051371 (0.01) ! muscle alpha-actinin binding; GO:0048487 (0.01) ! beta-tubulin binding; GO:0046982 (0.01) ! protein heterodimerization activity; GO:0044325 (0.01) ! ion channel binding; GO:0043426 (0.01) ! MRF binding; GO:0042803 (0.01) ! protein homodimerization activity; GO:0042800 (0.01) ! histone methyltransferase activity (H3-K4 specific); GO:0042043 (0.01) ! neurexin family protein binding; GO:0032182 (0.01) ! ubiquitin-like protein binding; GO:0030507 (0.01) ! spectrin binding; GO:0030506 (0.01) ! ankyrin binding; GO:0030332 (0.01) ! cyclin binding; GO:0019905 (0.01) ! syntaxin binding; GO:0019902 (0.01) ! phosphatase binding; GO:0017124 (0.01) ! SH3 domain binding; GO:0017056 (0.01) ! structural constituent of nuclear pore; GO:0017049 (0.01) ! GTP-Rho binding; GO:0016791 (0.01) ! phosphatase activity; GO:0015279 (0.01) ! store-operated calcium channel activity; GO:0015276 (0.01) ! ligand-gated ion channel activity; GO:0008331 (0.01) ! high voltage-gated calcium channel activity; GO:0008236 (0.01) ! serine-type peptidase activity; GO:0008201 (0.01) ! heparin binding; GO:0008139 (0.01) ! nuclear localization sequence binding; GO:0008017 (0.01) ! microtubule binding; GO:0008013 (0.01) ! beta-catenin binding; GO:0005546 (0.01) ! phosphatidylinositol-4,5-bisphosphate binding; GO:0005525 (0.01) ! GTP binding; GO:0005522 (0.01) ! profilin binding; GO:0005516 (0.01) ! calmodulin binding; GO:0005487 (0.01) ! nucleocytoplasmic transporter activity; GO:0005200 (0.01) ! structural constituent of cytoskeleton; GO:0005089 (0.01) ! Rho guanyl-nucleotide exchange factor activity; GO:0004864 (0.01) ! protein phosphatase inhibitor activity; GO:0004860 (0.01) ! protein kinase inhibitor activity; GO:0004843 (0.01) ! thiol-dependent ubiquitin-specific protease activity; GO:0004806 (0.01) ! triglyceride lipase activity; GO:0004715 (0.01) ! non-membrane spanning protein tyrosine kinase activity; GO:0004702 (0.01) ! receptor signaling protein serine/threonine kinase activity; GO:0004620 (0.01) ! phospholipase activity; GO:0004536 (0.01) ! deoxyribonuclease activity; GO:0004525 (0.01) ! ribonuclease III activity; GO:0004407 (0.01) ! histone deacetylase activity; GO:0004402 (0.01) ! histone acetyltransferase activity; GO:0004197 (0.01) ! cysteine-type endopeptidase activity; GO:0003924 (0.01) ! GTPase activity; GO:0003729 (0.01) ! mRNA binding; GO:0003725 (0.01) ! double-stranded RNA binding; GO:0003713 (0.01) ! transcription coactivator activity; GO:0003684 (0.01) ! damaged DNA binding; GO:0002020 (0.01) ! protease binding; GO:0001595 (0.01) ! angiotensin receptor activity; GO:0001106 (0.01) ! RNA polymerase II transcription corepressor activity; GO:0001078 (0.01) ! transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; GO:0001047 (0.01) ! core promoter binding; GO:0000976 (0.01) ! transcription regulatory region sequence-specific DNA binding GO:0009987 (0.61) ! cellular process; GO:0044699 (0.53) ! single-organism process; GO:0065007 (0.52) ! biological regulation; GO:0050789 (0.44) ! regulation of biological process; GO:0050794 (0.42) ! regulation of cellular process; GO:0044763 (0.41) ! single-organism cellular process; GO:0044767 (0.27) ! single-organism developmental process; GO:0071704 (0.25) ! organic substance metabolic process; GO:0016043 (0.25) ! cellular component organization; GO:0044238 (0.24) ! primary metabolic process; GO:0044237 (0.24) ! cellular metabolic process; GO:0051179 (0.23) ! localization; GO:0044260 (0.22) ! cellular macromolecule metabolic process; GO:0007165 (0.22) ! signal transduction; GO:0006810 (0.22) ! transport; GO:0032501 (0.21) ! multicellular organismal process; GO:0065008 (0.19) ! regulation of biological quality; GO:0048856 (0.18) ! anatomical structure development; GO:0048519 (0.18) ! negative regulation of biological process; GO:0048518 (0.18) ! positive regulation of biological process; GO:0044707 (0.18) ! single-multicellular organism process; GO:0048522 (0.17) ! positive regulation of cellular process; GO:0019222 (0.16) ! regulation of metabolic process; GO:0060255 (0.15) ! regulation of macromolecule metabolic process; GO:0031323 (0.15) ! regulation of cellular metabolic process; GO:0080090 (0.14) ! regulation of primary metabolic process; GO:0048523 (0.14) ! negative regulation of cellular process; GO:0050896 (0.13) ! response to stimulus; GO:0009653 (0.13) ! anatomical structure morphogenesis; GO:0006996 (0.13) ! organelle organization; GO:0044267 (0.12) ! cellular protein metabolic process; GO:0031326 (0.12) ! regulation of cellular biosynthetic process; GO:0019219 (0.12) ! regulation of nucleobase-containing compound metabolic process; GO:0010468 (0.12) ! regulation of gene expression; GO:0007166 (0.12) ! cell surface receptor signaling pathway; GO:1901360 (0.11) ! organic cyclic compound metabolic process; GO:0051641 (0.11) ! cellular localization; GO:0048869 (0.11) ! cellular developmental process; GO:0034641 (0.11) ! cellular nitrogen compound metabolic process; GO:0022607 (0.11) ! cellular component assembly; GO:0016192 (0.11) ! vesicle-mediated transport; GO:0010605 (0.11) ! negative regulation of macromolecule metabolic process; GO:0006464 (0.11) ! cellular protein modification process; GO:0006355 (0.11) ! regulation of transcription, DNA-templated; GO:0051649 (0.10) ! establishment of localization in cell; GO:0050793 (0.10) ! regulation of developmental process; GO:0044765 (0.10) ! single-organism transport; GO:0023051 (0.10) ! regulation of signaling; GO:0016070 (0.10) ! RNA metabolic process; GO:0010646 (0.10) ! regulation of cell communication; GO:0007010 (0.10) ! cytoskeleton organization; GO:0071702 (0.09) ! organic substance transport; GO:0051716 (0.09) ! cellular response to stimulus; GO:0051239 (0.09) ! regulation of multicellular organismal process; GO:0051173 (0.09) ! positive regulation of nitrogen compound metabolic process; GO:0051128 (0.09) ! regulation of cellular component organization; GO:0043933 (0.09) ! macromolecular complex subunit organization; GO:0031325 (0.09) ! positive regulation of cellular metabolic process; GO:0010629 (0.09) ! negative regulation of gene expression; GO:0010604 (0.09) ! positive regulation of macromolecule metabolic process; GO:0006950 (0.09) ! response to stress; GO:2000026 (0.08) ! regulation of multicellular organismal development; GO:1902680 (0.08) ! positive regulation of RNA biosynthetic process; GO:1902589 (0.08) ! single-organism organelle organization; GO:0046907 (0.08) ! intracellular transport; GO:0032774 (0.08) ! RNA biosynthetic process; GO:0010628 (0.08) ! positive regulation of gene expression; GO:0009966 (0.08) ! regulation of signal transduction; GO:0090066 (0.07) ! regulation of anatomical structure size; GO:0065009 (0.07) ! regulation of molecular function; GO:0048731 (0.07) ! system development; GO:0045595 (0.07) ! regulation of cell differentiation; GO:0034645 (0.07) ! cellular macromolecule biosynthetic process; GO:0033554 (0.07) ! cellular response to stress; GO:0032879 (0.07) ! regulation of localization; GO:0008104 (0.07) ! protein localization; GO:0006897 (0.07) ! endocytosis; GO:0006396 (0.07) ! RNA processing; GO:0050790 (0.06) ! regulation of catalytic activity; GO:0046782 (0.06) ! regulation of viral transcription; GO:0034660 (0.06) ! ncRNA metabolic process; GO:0031324 (0.06) ! negative regulation of cellular metabolic process; GO:0019827 (0.06) ! stem cell population maintenance; GO:0016458 (0.06) ! gene silencing; GO:0007267 (0.06) ! cell-cell signaling; GO:0007169 (0.06) ! transmembrane receptor protein tyrosine kinase signaling pathway; GO:0006928 (0.06) ! movement of cell or subcellular component; GO:0006368 (0.06) ! transcription elongation from RNA polymerase II promoter; GO:0006367 (0.06) ! transcription initiation from RNA polymerase II promoter; GO:0006366 (0.06) ! transcription from RNA polymerase II promoter; GO:0006325 (0.06) ! chromatin organization; GO:0006259 (0.06) ! DNA metabolic process; GO:0000398 (0.06) ! mRNA splicing, via spliceosome; GO:0071705 (0.05) ! nitrogen compound transport; GO:0065003 (0.05) ! macromolecular complex assembly; GO:0051049 (0.05) ! regulation of transport; GO:0050434 (0.05) ! positive regulation of viral transcription; GO:0048584 (0.05) ! positive regulation of response to stimulus; GO:0046331 (0.05) ! lateral inhibition; GO:0045664 (0.05) ! regulation of neuron differentiation; GO:0044719 (0.05) ! regulation of imaginal disc-derived wing size; GO:0044710 (0.05) ! single-organism metabolic process; GO:0042795 (0.05) ! snRNA transcription from RNA polymerase II promoter; GO:0040005 (0.05) ! chitin-based cuticle attachment to epithelium; GO:0035019 (0.05) ! somatic stem cell population maintenance; GO:0033120 (0.05) ! positive regulation of RNA splicing; GO:0032940 (0.05) ! secretion by cell; GO:0031344 (0.05) ! regulation of cell projection organization; GO:0031047 (0.05) ! gene silencing by RNA; GO:0030036 (0.05) ! actin cytoskeleton organization; GO:0022604 (0.05) ! regulation of cell morphogenesis; GO:0015031 (0.05) ! protein transport; GO:0008543 (0.05) ! fibroblast growth factor receptor signaling pathway; GO:0008362 (0.05) ! chitin-based embryonic cuticle biosynthetic process; GO:0007623 (0.05) ! circadian rhythm; GO:0007475 (0.05) ! apposition of dorsal and ventral imaginal disc-derived wing surfaces; GO:0007424 (0.05) ! open tracheal system development; GO:0007275 (0.05) ! multicellular organism development; GO:0007017 (0.05) ! microtubule-based process; GO:0006370 (0.05) ! 7-methylguanosine mRNA capping; GO:0006353 (0.05) ! DNA-templated transcription, termination; GO:0006283 (0.05) ! transcription-coupled nucleotide-excision repair; GO:0003008 (0.05) ! system process; GO:0001172 (0.05) ! transcription, RNA-templated; GO:1902580 (0.04) ! single-organism cellular localization; GO:1902531 (0.04) ! regulation of intracellular signal transduction; GO:0099643 (0.04) ! signal release from synapse; GO:0099531 (0.04) ! presynaptic process involved in chemical synaptic transmission; GO:0099003 (0.04) ! vesicle mediated transport in synapse; GO:0060627 (0.04) ! regulation of vesicle-mediated transport; GO:0050770 (0.04) ! regulation of axonogenesis; GO:0050658 (0.04) ! RNA transport; GO:0048646 (0.04) ! anatomical structure formation involved in morphogenesis; GO:0048589 (0.04) ! developmental growth; GO:0048513 (0.04) ! animal organ development; GO:0045892 (0.04) ! negative regulation of transcription, DNA-templated; GO:0043009 (0.04) ! chordate embryonic development; GO:0042221 (0.04) ! response to chemical; GO:0034622 (0.04) ! cellular macromolecular complex assembly; GO:0032989 (0.04) ! cellular component morphogenesis; GO:0030518 (0.04) ! intracellular steroid hormone receptor signaling pathway; GO:0030154 (0.04) ! cell differentiation; GO:0030030 (0.04) ! cell projection organization; GO:0022414 (0.04) ! reproductive process; GO:0016567 (0.04) ! protein ubiquitination; GO:0010941 (0.04) ! regulation of cell death; GO:0009967 (0.04) ! positive regulation of signal transduction; GO:0007155 (0.04) ! cell adhesion; GO:0007015 (0.04) ! actin filament organization; GO:0006898 (0.04) ! receptor-mediated endocytosis; GO:0006886 (0.04) ! intracellular protein transport; GO:0006811 (0.04) ! ion transport; GO:0006796 (0.04) ! phosphate-containing compound metabolic process; GO:0006461 (0.04) ! protein complex assembly; GO:0006357 (0.04) ! regulation of transcription from RNA polymerase II promoter; GO:1903530 (0.03) ! regulation of secretion by cell; GO:1902582 (0.03) ! single-organism intracellular transport; GO:0098609 (0.03) ! cell-cell adhesion; GO:0070887 (0.03) ! cellular response to chemical stimulus; GO:0055085 (0.03) ! transmembrane transport; GO:0051704 (0.03) ! multi-organism process; GO:0051241 (0.03) ! negative regulation of multicellular organismal process; GO:0051240 (0.03) ! positive regulation of multicellular organismal process; GO:0051130 (0.03) ! positive regulation of cellular component organization; GO:0051093 (0.03) ! negative regulation of developmental process; GO:0050877 (0.03) ! neurological system process; GO:0048858 (0.03) ! cell projection morphogenesis; GO:0048488 (0.03) ! synaptic vesicle endocytosis; GO:0048468 (0.03) ! cell development; GO:0048193 (0.03) ! Golgi vesicle transport; GO:0045893 (0.03) ! positive regulation of transcription, DNA-templated; GO:0045596 (0.03) ! negative regulation of cell differentiation; GO:0044702 (0.03) ! single organism reproductive process; GO:0044093 (0.03) ! positive regulation of molecular function; GO:0043087 (0.03) ! regulation of GTPase activity; GO:0042981 (0.03) ! regulation of apoptotic process; GO:0042592 (0.03) ! homeostatic process; GO:0042391 (0.03) ! regulation of membrane potential; GO:0042127 (0.03) ! regulation of cell proliferation; GO:0040011 (0.03) ! locomotion; GO:0035556 (0.03) ! intracellular signal transduction; GO:0034613 (0.03) ! cellular protein localization; GO:0033227 (0.03) ! dsRNA transport; GO:0033043 (0.03) ! regulation of organelle organization; GO:0032268 (0.03) ! regulation of cellular protein metabolic process; GO:0030705 (0.03) ! cytoskeleton-dependent intracellular transport; GO:0019220 (0.03) ! regulation of phosphate metabolic process; GO:0018193 (0.03) ! peptidyl-amino acid modification; GO:0017038 (0.03) ! protein import; GO:0016570 (0.03) ! histone modification; GO:0016049 (0.03) ! cell growth; GO:0010927 (0.03) ! cellular component assembly involved in morphogenesis; GO:0010720 (0.03) ! positive regulation of cell development; GO:0010033 (0.03) ! response to organic substance; GO:0009628 (0.03) ! response to abiotic stimulus; GO:0009605 (0.03) ! response to external stimulus; GO:0007269 (0.03) ! neurotransmitter secretion; GO:0007219 (0.03) ! Notch signaling pathway; GO:0007018 (0.03) ! microtubule-based movement; GO:0006914 (0.03) ! autophagy; GO:0006812 (0.03) ! cation transport; GO:0006468 (0.03) ! protein phosphorylation; GO:0002376 (0.03) ! immune system process; GO:0001701 (0.03) ! in utero embryonic development; GO:0000226 (0.03) ! microtubule cytoskeleton organization; GO:1903047 (0.02) ! mitotic cell cycle process; GO:1902287 (0.02) ! semaphorin-plexin signaling pathway involved in axon guidance; GO:0086010 (0.02) ! membrane depolarization during action potential; GO:0071310 (0.02) ! cellular response to organic substance; GO:0071214 (0.02) ! cellular response to abiotic stimulus; GO:0070925 (0.02) ! organelle assembly; GO:0061061 (0.02) ! muscle structure development; GO:0061024 (0.02) ! membrane organization; GO:0060026 (0.02) ! convergent extension; GO:0051640 (0.02) ! organelle localization; GO:0051606 (0.02) ! detection of stimulus; GO:0051493 (0.02) ! regulation of cytoskeleton organization; GO:0051345 (0.02) ! positive regulation of hydrolase activity; GO:0051129 (0.02) ! negative regulation of cellular component organization; GO:0051050 (0.02) ! positive regulation of transport; GO:0050772 (0.02) ! positive regulation of axonogenesis; GO:0048878 (0.02) ! chemical homeostasis; GO:0048812 (0.02) ! neuron projection morphogenesis; GO:0048675 (0.02) ! axon extension; GO:0046486 (0.02) ! glycerolipid metabolic process; GO:0045944 (0.02) ! positive regulation of transcription from RNA polymerase II promoter; GO:0045936 (0.02) ! negative regulation of phosphate metabolic process; GO:0045859 (0.02) ! regulation of protein kinase activity; GO:0045747 (0.02) ! positive regulation of Notch signaling pathway; GO:0045214 (0.02) ! sarcomere organization; GO:0043623 (0.02) ! cellular protein complex assembly; GO:0043254 (0.02) ! regulation of protein complex assembly; GO:0043086 (0.02) ! negative regulation of catalytic activity; GO:0043065 (0.02) ! positive regulation of apoptotic process; GO:0040008 (0.02) ! regulation of growth; GO:0033365 (0.02) ! protein localization to organelle; GO:0032970 (0.02) ! regulation of actin filament-based process; GO:0032535 (0.02) ! regulation of cellular component size; GO:0031400 (0.02) ! negative regulation of protein modification process; GO:0030334 (0.02) ! regulation of cell migration; GO:0030001 (0.02) ! metal ion transport; GO:0019725 (0.02) ! cellular homeostasis; GO:0018205 (0.02) ! peptidyl-lysine modification; GO:0017158 (0.02) ! regulation of calcium ion-dependent exocytosis; GO:0016477 (0.02) ! cell migration; GO:0016337 (0.02) ! single organismal cell-cell adhesion; GO:0016050 (0.02) ! vesicle organization; GO:0015032 (0.02) ! storage protein import into fat body; GO:0010817 (0.02) ! regulation of hormone levels; GO:0009997 (0.02) ! negative regulation of cardioblast cell fate specification; GO:0009968 (0.02) ! negative regulation of signal transduction; GO:0008360 (0.02) ! regulation of cell shape; GO:0008283 (0.02) ! cell proliferation; GO:0007600 (0.02) ! sensory perception; GO:0007416 (0.02) ! synapse assembly; GO:0007276 (0.02) ! gamete generation; GO:0007186 (0.02) ! G-protein coupled receptor signaling pathway; GO:0007162 (0.02) ! negative regulation of cell adhesion; GO:0006952 (0.02) ! defense response; GO:0006936 (0.02) ! muscle contraction; GO:0006888 (0.02) ! ER to Golgi vesicle-mediated transport; GO:0006336 (0.02) ! DNA replication-independent nucleosome assembly; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0000122 (0.02) ! negative regulation of transcription from RNA polymerase II promoter; GO:1902533 (0.01) ! positive regulation of intracellular signal transduction; GO:1902275 (0.01) ! regulation of chromatin organization; GO:1901361 (0.01) ! organic cyclic compound catabolic process; GO:0090675 (0.01) ! intermicrovillar adhesion; GO:0090502 (0.01) ! RNA phosphodiester bond hydrolysis, endonucleolytic; GO:0090276 (0.01) ! regulation of peptide hormone secretion; GO:0090257 (0.01) ! regulation of muscle system process; GO:0090114 (0.01) ! COPII-coated vesicle budding; GO:0071407 (0.01) ! cellular response to organic cyclic compound; GO:0071300 (0.01) ! cellular response to retinoic acid; GO:0071241 (0.01) ! cellular response to inorganic substance; GO:0071156 (0.01) ! regulation of cell cycle arrest; GO:0070933 (0.01) ! histone H4 deacetylation; GO:0060988 (0.01) ! lipid tube assembly; GO:0060271 (0.01) ! cilium morphogenesis; GO:0060047 (0.01) ! heart contraction; GO:0060041 (0.01) ! retina development in camera-type eye; GO:0060024 (0.01) ! rhythmic synaptic transmission; GO:0055088 (0.01) ! lipid homeostasis; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051601 (0.01) ! exocyst localization; GO:0051592 (0.01) ! response to calcium ion; GO:0051056 (0.01) ! regulation of small GTPase mediated signal transduction; GO:0051017 (0.01) ! actin filament bundle assembly; GO:0051016 (0.01) ! barbed-end actin filament capping; GO:0050982 (0.01) ! detection of mechanical stimulus; GO:0050906 (0.01) ! detection of stimulus involved in sensory perception; GO:0050890 (0.01) ! cognition; GO:0050885 (0.01) ! neuromuscular process controlling balance; GO:0050883 (0.01) ! musculoskeletal movement, spinal reflex action; GO:0050878 (0.01) ! regulation of body fluid levels; GO:0050829 (0.01) ! defense response to Gram-negative bacterium; GO:0050709 (0.01) ! negative regulation of protein secretion; GO:0050684 (0.01) ! regulation of mRNA processing; GO:0048919 (0.01) ! posterior lateral line neuromast development; GO:0048813 (0.01) ! dendrite morphogenesis; GO:0048791 (0.01) ! calcium ion-regulated exocytosis of neurotransmitter; GO:0048739 (0.01) ! cardiac muscle fiber development; GO:0048738 (0.01) ! cardiac muscle tissue development; GO:0048711 (0.01) ! positive regulation of astrocyte differentiation; GO:0048598 (0.01) ! embryonic morphogenesis; GO:0048568 (0.01) ! embryonic organ development; GO:0048514 (0.01) ! blood vessel morphogenesis; GO:0048477 (0.01) ! oogenesis; GO:0048266 (0.01) ! behavioral response to pain; GO:0048265 (0.01) ! response to pain; GO:0046488 (0.01) ! phosphatidylinositol metabolic process; GO:0046426 (0.01) ! negative regulation of JAK-STAT cascade; GO:0045956 (0.01) ! positive regulation of calcium ion-dependent exocytosis; GO:0045937 (0.01) ! positive regulation of phosphate metabolic process; GO:0045807 (0.01) ! positive regulation of endocytosis; GO:0045682 (0.01) ! regulation of epidermis development; GO:0045665 (0.01) ! negative regulation of neuron differentiation; GO:0045089 (0.01) ! positive regulation of innate immune response; GO:0045087 (0.01) ! innate immune response; GO:0044419 (0.01) ! interspecies interaction between organisms; GO:0044351 (0.01) ! macropinocytosis; GO:0044236 (0.01) ! multicellular organism metabolic process; GO:0044089 (0.01) ! positive regulation of cellular component biogenesis; GO:0043968 (0.01) ! histone H2A acetylation; GO:0043967 (0.01) ! histone H4 acetylation; GO:0043547 (0.01) ! positive regulation of GTPase activity; GO:0043524 (0.01) ! negative regulation of neuron apoptotic process; GO:0043409 (0.01) ! negative regulation of MAPK cascade; GO:0043405 (0.01) ! regulation of MAP kinase activity; GO:0043279 (0.01) ! response to alkaloid; GO:0043122 (0.01) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043113 (0.01) ! receptor clustering; GO:0042787 (0.01) ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process; GO:0042692 (0.01) ! muscle cell differentiation; GO:0042461 (0.01) ! photoreceptor cell development; GO:0042445 (0.01) ! hormone metabolic process; GO:0042147 (0.01) ! retrograde transport, endosome to Golgi; GO:0042133 (0.01) ! neurotransmitter metabolic process; GO:0042110 (0.01) ! T cell activation; GO:0042059 (0.01) ! negative regulation of epidermal growth factor receptor signaling pathway; GO:0038166 (0.01) ! angiotensin-activated signaling pathway; GO:0038083 (0.01) ! peptidyl-tyrosine autophosphorylation; GO:0035690 (0.01) ! cellular response to drug; GO:0035303 (0.01) ! regulation of dephosphorylation; GO:0035264 (0.01) ! multicellular organism growth; GO:0035249 (0.01) ! synaptic transmission, glutamatergic; GO:0035082 (0.01) ! axoneme assembly; GO:0034968 (0.01) ! histone lysine methylation; GO:0034644 (0.01) ! cellular response to UV; GO:0034599 (0.01) ! cellular response to oxidative stress; GO:0034220 (0.01) ! ion transmembrane transport; GO:0034109 (0.01) ! homotypic cell-cell adhesion; GO:0032870 (0.01) ! cellular response to hormone stimulus; GO:0032786 (0.01) ! positive regulation of DNA-templated transcription, elongation; GO:0032785 (0.01) ! negative regulation of DNA-templated transcription, elongation; GO:0032532 (0.01) ! regulation of microvillus length; GO:0032414 (0.01) ! positive regulation of ion transmembrane transporter activity; GO:0032353 (0.01) ! negative regulation of hormone biosynthetic process; GO:0032270 (0.01) ! positive regulation of cellular protein metabolic process; GO:0032101 (0.01) ! regulation of response to external stimulus; GO:0032092 (0.01) ! positive regulation of protein binding; GO:0031623 (0.01) ! receptor internalization; GO:0031507 (0.01) ! heterochromatin assembly; GO:0031054 (0.01) ! pre-miRNA processing; GO:0031053 (0.01) ! primary miRNA processing; GO:0030644 (0.01) ! cellular chloride ion homeostasis; GO:0030521 (0.01) ! androgen receptor signaling pathway; GO:0030516 (0.01) ! regulation of axon extension; GO:0030422 (0.01) ! production of siRNA involved in RNA interference; GO:0030258 (0.01) ! lipid modification; GO:0030241 (0.01) ! skeletal muscle myosin thick filament assembly; GO:0030240 (0.01) ! skeletal muscle thin filament assembly; GO:0030177 (0.01) ! positive regulation of Wnt signaling pathway; GO:0022411 (0.01) ! cellular component disassembly; GO:0022008 (0.01) ! neurogenesis; GO:0021750 (0.01) ! vestibular nucleus development; GO:0021702 (0.01) ! cerebellar Purkinje cell differentiation; GO:0021680 (0.01) ! cerebellar Purkinje cell layer development; GO:0021679 (0.01) ! cerebellar molecular layer development; GO:0021591 (0.01) ! ventricular system development; GO:0021590 (0.01) ! cerebellum maturation; GO:0021522 (0.01) ! spinal cord motor neuron differentiation; GO:0019886 (0.01) ! antigen processing and presentation of exogenous peptide antigen via MHC class II; GO:0019433 (0.01) ! triglyceride catabolic process; GO:0019233 (0.01) ! sensory perception of pain; GO:0019226 (0.01) ! transmission of nerve impulse; GO:0019221 (0.01) ! cytokine-mediated signaling pathway; GO:0018105 (0.01) ! peptidyl-serine phosphorylation; GO:0016579 (0.01) ! protein deubiquitination; GO:0016311 (0.01) ! dephosphorylation; GO:0016080 (0.01) ! synaptic vesicle targeting; GO:0014866 (0.01) ! skeletal myofibril assembly; GO:0014056 (0.01) ! regulation of acetylcholine secretion, neurotransmission; GO:0014051 (0.01) ! gamma-aminobutyric acid secretion; GO:0010638 (0.01) ! positive regulation of organelle organization; GO:0009593 (0.01) ! detection of chemical stimulus; GO:0008285 (0.01) ! negative regulation of cell proliferation; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008277 (0.01) ! regulation of G-protein coupled receptor protein signaling pathway; GO:0008219 (0.01) ! cell death; GO:0007628 (0.01) ! adult walking behavior; GO:0007565 (0.01) ! female pregnancy; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007507 (0.01) ! heart development; GO:0007420 (0.01) ! brain development; GO:0007417 (0.01) ! central nervous system development; GO:0007283 (0.01) ! spermatogenesis; GO:0007274 (0.01) ! neuromuscular synaptic transmission; GO:0007265 (0.01) ! Ras protein signal transduction; GO:0007214 (0.01) ! gamma-aminobutyric acid signaling pathway; GO:0007204 (0.01) ! positive regulation of cytosolic calcium ion concentration; GO:0007158 (0.01) ! neuron cell-cell adhesion; GO:0006997 (0.01) ! nucleus organization; GO:0006941 (0.01) ! striated muscle contraction; GO:0006939 (0.01) ! smooth muscle contraction; GO:0006893 (0.01) ! Golgi to plasma membrane transport; GO:0006828 (0.01) ! manganese ion transport; GO:0006816 (0.01) ! calcium ion transport; GO:0006623 (0.01) ! protein targeting to vacuole; GO:0006606 (0.01) ! protein import into nucleus; GO:0006469 (0.01) ! negative regulation of protein kinase activity; GO:0006405 (0.01) ! RNA export from nucleus; GO:0006342 (0.01) ! chromatin silencing; GO:0006006 (0.01) ! glucose metabolic process; GO:0003007 (0.01) ! heart morphogenesis; GO:0001894 (0.01) ! tissue homeostasis; GO:0001817 (0.01) ! regulation of cytokine production; GO:0001525 (0.01) ! angiogenesis; GO:0001501 (0.01) ! skeletal system development; GO:0000902 (0.01) ! cell morphogenesis; GO:0000278 (0.01) ! mitotic cell cycle; GO:0000165 (0.01) ! MAPK cascade; GO:0000147 (0.01) ! actin cortical patch assembly; GO:0000096 (0.01) ! sulfur amino acid metabolic process; GO:0000086 (0.01) ! G2/M transition of mitotic cell cycle GO:0044424 (1.00) ! intracellular part; GO:0032991 (0.64) ! macromolecular complex; GO:0043234 (0.63) ! protein complex; GO:0043226 (0.63) ! organelle; GO:0043229 (0.61) ! intracellular organelle; GO:0005737 (0.60) ! cytoplasm; GO:0044422 (0.49) ! organelle part; GO:0044446 (0.48) ! intracellular organelle part; GO:0043227 (0.45) ! membrane-bounded organelle; GO:0044444 (0.44) ! cytoplasmic part; GO:0043231 (0.42) ! intracellular membrane-bounded organelle; GO:0016020 (0.41) ! membrane; GO:0044428 (0.38) ! nuclear part; GO:0043232 (0.33) ! intracellular non-membrane-bounded organelle; GO:1902494 (0.32) ! catalytic complex; GO:1990234 (0.31) ! transferase complex; GO:0005634 (0.30) ! nucleus; GO:0044451 (0.24) ! nucleoplasm part; GO:0061695 (0.23) ! transferase complex, transferring phosphorus-containing groups; GO:0005654 (0.23) ! nucleoplasm; GO:0005829 (0.18) ! cytosol; GO:0044425 (0.17) ! membrane part; GO:0005886 (0.17) ! plasma membrane; GO:0044430 (0.16) ! cytoskeletal part; GO:0005665 (0.16) ! DNA-directed RNA polymerase II, core complex; GO:0044445 (0.14) ! cytosolic part; GO:0044459 (0.12) ! plasma membrane part; GO:0044421 (0.11) ! extracellular region part; GO:0005856 (0.09) ! cytoskeleton; GO:0044454 (0.08) ! nuclear chromosome part; GO:0031988 (0.08) ! membrane-bounded vesicle; GO:0031248 (0.08) ! protein acetyltransferase complex; GO:0031224 (0.08) ! intrinsic component of membrane; GO:0030529 (0.08) ! intracellular ribonucleoprotein complex; GO:0005874 (0.08) ! microtubule; GO:0005811 (0.08) ! lipid particle; GO:0005730 (0.08) ! nucleolus; GO:0005618 (0.08) ! cell wall; GO:0000785 (0.08) ! chromatin; GO:0034081 (0.07) ! polyketide synthase complex; GO:0031416 (0.07) ! NatB complex; GO:0031415 (0.07) ! NatA complex; GO:0022626 (0.07) ! cytosolic ribosome; GO:0009360 (0.07) ! DNA polymerase III complex; GO:0005887 (0.07) ! integral component of plasma membrane; GO:0005876 (0.07) ! spindle microtubule; GO:0005835 (0.07) ! fatty acid synthase complex; GO:0005777 (0.07) ! peroxisome; GO:0005719 (0.07) ! nuclear euchromatin; GO:0000974 (0.07) ! Prp19 complex; GO:0097458 (0.06) ! neuron part; GO:0005794 (0.06) ! Golgi apparatus; GO:0098796 (0.05) ! membrane protein complex; GO:0044463 (0.05) ! cell projection part; GO:0042995 (0.05) ! cell projection; GO:0031012 (0.05) ! extracellular matrix; GO:0070847 (0.04) ! core mediator complex; GO:0070062 (0.04) ! extracellular exosome; GO:0043005 (0.04) ! neuron projection; GO:0030054 (0.04) ! cell junction; GO:0016592 (0.04) ! mediator complex; GO:0016023 (0.04) ! cytoplasmic, membrane-bounded vesicle; GO:0098590 (0.03) ! plasma membrane region; GO:0048471 (0.03) ! perinuclear region of cytoplasm; GO:0045202 (0.03) ! synapse; GO:0044456 (0.03) ! synapse part; GO:0044448 (0.03) ! cell cortex part; GO:0044431 (0.03) ! Golgi apparatus part; GO:0043235 (0.03) ! receptor complex; GO:0030135 (0.03) ! coated vesicle; GO:0005912 (0.03) ! adherens junction; GO:1902495 (0.02) ! transmembrane transporter complex; GO:0098797 (0.02) ! plasma membrane protein complex; GO:0098791 (0.02) ! Golgi subcompartment; GO:0098588 (0.02) ! bounding membrane of organelle; GO:0044432 (0.02) ! endoplasmic reticulum part; GO:0033267 (0.02) ! axon part; GO:0030425 (0.02) ! dendrite; GO:0030136 (0.02) ! clathrin-coated vesicle; GO:0030133 (0.02) ! transport vesicle; GO:0030120 (0.02) ! vesicle coat; GO:0030018 (0.02) ! Z disc; GO:0019897 (0.02) ! extrinsic component of plasma membrane; GO:0009986 (0.02) ! cell surface; GO:0005913 (0.02) ! cell-cell adherens junction; GO:0005905 (0.02) ! clathrin-coated pit; GO:0005871 (0.02) ! kinesin complex; GO:0005768 (0.02) ! endosome; GO:0005615 (0.02) ! extracellular space; GO:0002116 (0.02) ! semaphorin receptor complex; GO:0098805 (0.01) ! whole membrane; GO:0098802 (0.01) ! plasma membrane receptor complex; GO:0097525 (0.01) ! spliceosomal snRNP complex; GO:0071004 (0.01) ! U2-type prespliceosome; GO:0045211 (0.01) ! postsynaptic membrane; GO:0044666 (0.01) ! MLL3/4 complex; GO:0044214 (0.01) ! spanning component of plasma membrane; GO:0043195 (0.01) ! terminal bouton; GO:0043025 (0.01) ! neuronal cell body; GO:0034703 (0.01) ! cation channel complex; GO:0032044 (0.01) ! DSIF complex; GO:0031674 (0.01) ! I band; GO:0031672 (0.01) ! A band; GO:0031528 (0.01) ! microvillus membrane; GO:0031526 (0.01) ! brush border membrane; GO:0031430 (0.01) ! M band; GO:0031234 (0.01) ! extrinsic component of cytoplasmic side of plasma membrane; GO:0030659 (0.01) ! cytoplasmic vesicle membrane; GO:0030479 (0.01) ! actin cortical patch; GO:0030426 (0.01) ! growth cone; GO:0030424 (0.01) ! axon; GO:0030139 (0.01) ! endocytic vesicle; GO:0030134 (0.01) ! ER to Golgi transport vesicle; GO:0030127 (0.01) ! COPII vesicle coat; GO:0030125 (0.01) ! clathrin vesicle coat; GO:0017053 (0.01) ! transcriptional repressor complex; GO:0016607 (0.01) ! nuclear speck; GO:0016324 (0.01) ! apical plasma membrane; GO:0016010 (0.01) ! dystrophin-associated glycoprotein complex; GO:0015630 (0.01) ! microtubule cytoskeleton; GO:0015629 (0.01) ! actin cytoskeleton; GO:0014069 (0.01) ! postsynaptic density; GO:0009277 (0.01) ! fungal-type cell wall; GO:0008290 (0.01) ! F-actin capping protein complex; GO:0005930 (0.01) ! axoneme; GO:0005925 (0.01) ! focal adhesion; GO:0005865 (0.01) ! striated muscle thin filament; GO:0005859 (0.01) ! muscle myosin complex; GO:0005813 (0.01) ! centrosome; GO:0005802 (0.01) ! trans-Golgi network; GO:0005789 (0.01) ! endoplasmic reticulum membrane; GO:0005769 (0.01) ! early endosome; GO:0005622 (0.01) ! intracellular; GO:0005578 (0.01) ! proteinaceous extracellular matrix; GO:0001891 (0.01) ! phagocytic cup; GO:0000145 (0.01) ! exocyst; GO:0000139 (0.01) ! Golgi membrane; GO:0000123 (0.01) ! histone acetyltransferase complex; GO:0000118 (0.01) ! histone deacetylase complex Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network. {ECO:0000305|PubMed:22472443, ECO:0000305|PubMed:26542808}. GO:0030124 ! AP-4 adaptor complex; GO:0005794 ! Golgi apparatus; GO:0030662 ! coated vesicle membrane; GO:0032588 ! trans-Golgi network membrane; GO:0031312 ! extrinsic component of organelle membrane; GO:0005515 ! protein binding; GO:0005737 ! cytoplasm; GO:0031965 ! nuclear membrane; GO:0016607 ! nuclear speck GO:0031410 ! cytoplasmic vesicle; GO:0016020 ! membrane; GO:0005829 ! cytosol 5 GO:0005515 ! protein binding 81228277-81239091 (17q25.3) MAAAPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESPGSSQCLLEYLLSRLHSSSGHGKLKVLKILLYLCSHGSSFFLLILKRNSAFIQEAAAFAGPPDPLHGNSLYQKVRAAAQDLGSTLFSDTVLPLAPSQPLGTPPATGMGSQARPHSTLQGFGYSKEHGRTAVRHQPGQAGGGWDELDSGPSSQNSSQNSDLSRVSDSGSHSGSDSHSGASREPGDLAERVEVVALSDCQQELSLVRTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRALCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAESRRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACPRLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEPSAFAFLNA OXLD1 Oxidoreductase-like domain-containing protein 1 OXLD1_HUMAN (Q5BKU9-1) GO:0003824 (0.94) ! catalytic activity; GO:0016491 (0.87) ! oxidoreductase activity; GO:0000166 (0.82) ! nucleotide binding; GO:0071949 (0.73) ! FAD binding; GO:0004128 (0.73) ! cytochrome-b5 reductase activity, acting on NAD(P)H; GO:0016211 (0.52) ! ammonia ligase activity; GO:0035639 (0.33) ! purine ribonucleoside triphosphate binding; GO:0032559 (0.33) ! adenyl ribonucleotide binding; GO:0032550 (0.33) ! purine ribonucleoside binding; GO:0030586 (0.14) ! [methionine synthase] reductase activity GO:0015701 (0.90) ! bicarbonate transport; GO:0009084 (0.53) ! glutamine family amino acid biosynthetic process; GO:0008652 (0.53) ! cellular amino acid biosynthetic process; GO:0006541 (0.53) ! glutamine metabolic process; GO:0071941 (0.34) ! nitrogen cycle metabolic process GO:0043231 (1.00) ! intracellular membrane-bounded organelle; GO:0044444 (0.94) ! cytoplasmic part; GO:0005739 (0.90) ! mitochondrion; GO:0005737 (0.66) ! cytoplasm; GO:0016020 (0.19) ! membrane; GO:0005634 (0.18) ! nucleus; GO:0005886 (0.16) ! plasma membrane; GO:0005829 (0.12) ! cytosol; GO:0044428 (0.11) ! nuclear part; GO:0043234 (0.08) ! protein complex; GO:0005654 (0.08) ! nucleoplasm; GO:0070062 (0.04) ! extracellular exosome; GO:0045202 (0.04) ! synapse; GO:0043197 (0.04) ! dendritic spine; GO:0034399 (0.04) ! nuclear periphery; GO:0030496 (0.04) ! midbody; GO:0030426 (0.04) ! growth cone; GO:0030027 (0.04) ! lamellipodium; GO:0008074 (0.04) ! guanylate cyclase complex, soluble; GO:0005915 (0.04) ! zonula adherens; GO:0005789 (0.04) ! endoplasmic reticulum membrane; GO:0005618 (0.04) ! cell wall; GO:0005576 (0.04) ! extracellular region 1 81665036-81666635 (17q25.3) Testis: 62.40; Spleen: 58.87; Cells - EBV-transformed lymphocytes: 51.45; Prostate: 48.01; Cells - Transformed fibroblasts: 42.18; Thyroid: 41.66; Skin - Sun Exposed (Lower leg): 41.25; Skin - Not Sun Exposed (Suprapubic): 39.93; Pituitary: 37.22; Adrenal Gland: 34.71; Nerve - Tibial: 34.24; Fallopian Tube: 34.19; Bladder: 33.59; Breast - Mammary Tissue: 32.95; Uterus: 32.84; Lung: 32.09; Small Intestine - Terminal Ileum: 31.68; Stomach: 30.27; Vagina: 29.77; Esophagus - Mucosa: 29.77; Brain - Cerebellar Hemisphere: 29.26; Cervix - Ectocervix: 29.11; Artery - Coronary: 28.88; Minor Salivary Gland: 28.60; Kidney - Cortex: 28.34; Esophagus - Muscularis: 28.12; Adipose - Subcutaneous: 28.09; Esophagus - Gastroesophageal Junction: 27.69; Brain - Cerebellum: 27.46; Colon - Sigmoid: 27.39; Cervix - Endocervix: 27.35; Ovary: 27.22; Artery - Aorta: 26.48; Colon - Transverse: 26.32; Brain - Frontal Cortex (BA9): 24.69; Brain - Spinal cord (cervical c-1): 23.95; Brain - Hypothalamus: 23.11; Brain - Cortex: 22.87; Adipose - Visceral (Omentum): 22.49; Brain - Nucleus accumbens (basal ganglia): 22.42; Artery - Tibial: 21.57; Brain - Caudate (basal ganglia): 20.83; Brain - Substantia nigra: 20.35; Brain - Putamen (basal ganglia): 20.14; Brain - Anterior cingulate cortex (BA24): 20.13; Brain - Hippocampus: 19.09; Brain - Amygdala: 18.07; Liver: 16.45; Whole Blood: 16.03; Heart - Atrial Appendage: 14.65; Pancreas: 13.57; Muscle - Skeletal: 11.88; Heart - Left Ventricle: 11.73; MLLRRVVEGGRAVAAAVRGSGARRFSSPDCCQRLPGGGSFLQRHHPGAQAPDGRRKFGTDHVEVGSQAGADGTRPPKASLPPELQPPTNCCMSGCPNCVWVEYADRLLQHFQDGGERALAALEEHVADENLKAFLRMEIRLHTRCGG CCDC57 Coiled-coil domain-containing protein 57 CCD57_HUMAN (Q2TAC2-1) GO:0097367 (0.44) ! carbohydrate derivative binding; GO:0035639 (0.41) ! purine ribonucleoside triphosphate binding; GO:0032559 (0.41) ! adenyl ribonucleotide binding; GO:0032550 (0.41) ! purine ribonucleoside binding; GO:0052813 (0.31) ! phosphatidylinositol bisphosphate kinase activity; GO:0052742 (0.31) ! phosphatidylinositol kinase activity; GO:0035004 (0.31) ! phosphatidylinositol 3-kinase activity; GO:0016307 (0.31) ! phosphatidylinositol phosphate kinase activity; GO:0004872 (0.08) ! receptor activity; GO:0008201 (0.05) ! heparin binding GO:0009987 (0.91) ! cellular process; GO:0044699 (0.81) ! single-organism process; GO:0044763 (0.77) ! single-organism cellular process; GO:0065007 (0.61) ! biological regulation; GO:0050794 (0.59) ! regulation of cellular process; GO:0016043 (0.56) ! cellular component organization; GO:0048518 (0.50) ! positive regulation of biological process; GO:0060255 (0.48) ! regulation of macromolecule metabolic process; GO:0010604 (0.46) ! positive regulation of macromolecule metabolic process; GO:0035556 (0.43) ! intracellular signal transduction; GO:0010468 (0.43) ! regulation of gene expression; GO:0048017 (0.41) ! inositol lipid-mediated signaling; GO:0071704 (0.40) ! organic substance metabolic process; GO:0044238 (0.40) ! primary metabolic process; GO:0044237 (0.40) ! cellular metabolic process; GO:1901576 (0.34) ! organic substance biosynthetic process; GO:0044249 (0.34) ! cellular biosynthetic process; GO:0032502 (0.34) ! developmental process; GO:0044767 (0.33) ! single-organism developmental process; GO:0006796 (0.33) ! phosphate-containing compound metabolic process; GO:0044710 (0.32) ! single-organism metabolic process; GO:0016310 (0.32) ! phosphorylation; GO:0046834 (0.31) ! lipid phosphorylation; GO:0007017 (0.31) ! microtubule-based process; GO:0006996 (0.31) ! organelle organization; GO:0006928 (0.31) ! movement of cell or subcellular component; GO:0006661 (0.31) ! phosphatidylinositol biosynthetic process; GO:0051179 (0.28) ! localization; GO:0051234 (0.24) ! establishment of localization; GO:0051641 (0.21) ! cellular localization; GO:0048869 (0.21) ! cellular developmental process; GO:0007018 (0.21) ! microtubule-based movement; GO:1902589 (0.20) ! single-organism organelle organization; GO:0051649 (0.19) ! establishment of localization in cell; GO:0022402 (0.19) ! cell cycle process; GO:0009653 (0.19) ! anatomical structure morphogenesis; GO:0006810 (0.19) ! transport; GO:0022607 (0.17) ! cellular component assembly; GO:0007010 (0.15) ! cytoskeleton organization; GO:0048522 (0.14) ! positive regulation of cellular process; GO:0032989 (0.14) ! cellular component morphogenesis; GO:0080090 (0.13) ! regulation of primary metabolic process; GO:0051128 (0.13) ! regulation of cellular component organization; GO:0050896 (0.13) ! response to stimulus; GO:0048856 (0.13) ! anatomical structure development; GO:0044260 (0.13) ! cellular macromolecule metabolic process; GO:0031323 (0.13) ! regulation of cellular metabolic process; GO:0046907 (0.12) ! intracellular transport; GO:0000902 (0.12) ! cell morphogenesis; GO:1903047 (0.11) ! mitotic cell cycle process; GO:0040011 (0.11) ! locomotion; GO:0032501 (0.11) ! multicellular organismal process; GO:0008104 (0.11) ! protein localization; GO:0003198 (0.11) ! epithelial to mesenchymal transition involved in endocardial cushion formation; GO:0048870 (0.10) ! cell motility; GO:0048646 (0.10) ! anatomical structure formation involved in morphogenesis; GO:0048519 (0.10) ! negative regulation of biological process; GO:0032268 (0.10) ! regulation of cellular protein metabolic process; GO:0022414 (0.10) ! reproductive process; GO:0006950 (0.10) ! response to stress; GO:0000226 (0.10) ! microtubule cytoskeleton organization; GO:1902578 (0.09) ! single-organism localization; GO:0070925 (0.09) ! organelle assembly; GO:0065009 (0.09) ! regulation of molecular function; GO:0051640 (0.09) ! organelle localization; GO:0048523 (0.09) ! negative regulation of cellular process; GO:0033043 (0.09) ! regulation of organelle organization; GO:0031325 (0.09) ! positive regulation of cellular metabolic process; GO:0065008 (0.08) ! regulation of biological quality; GO:0051726 (0.08) ! regulation of cell cycle; GO:0051656 (0.08) ! establishment of organelle localization; GO:0050790 (0.08) ! regulation of catalytic activity; GO:0034641 (0.08) ! cellular nitrogen compound metabolic process; GO:0032270 (0.08) ! positive regulation of cellular protein metabolic process; GO:0030030 (0.08) ! cell projection organization; GO:0010927 (0.08) ! cellular component assembly involved in morphogenesis; GO:0051336 (0.07) ! regulation of hydrolase activity; GO:0044267 (0.07) ! cellular protein metabolic process; GO:0043085 (0.07) ! positive regulation of catalytic activity; GO:0016477 (0.07) ! cell migration; GO:0016192 (0.07) ! vesicle-mediated transport; GO:0009628 (0.07) ! response to abiotic stimulus; GO:1903046 (0.06) ! meiotic cell cycle process; GO:1902580 (0.06) ! single-organism cellular localization; GO:0090304 (0.06) ! nucleic acid metabolic process; GO:0051345 (0.06) ! positive regulation of hydrolase activity; GO:0050793 (0.06) ! regulation of developmental process; GO:0045184 (0.06) ! establishment of protein localization; GO:0044765 (0.06) ! single-organism transport; GO:0044707 (0.06) ! single-multicellular organism process; GO:0043933 (0.06) ! macromolecular complex subunit organization; GO:0042127 (0.06) ! regulation of cell proliferation; GO:0040012 (0.06) ! regulation of locomotion; GO:0032879 (0.06) ! regulation of localization; GO:0030705 (0.06) ! cytoskeleton-dependent intracellular transport; GO:0030198 (0.06) ! extracellular matrix organization; GO:0030162 (0.06) ! regulation of proteolysis; GO:0030029 (0.06) ! actin filament-based process; GO:0010564 (0.06) ! regulation of cell cycle process; GO:0010033 (0.06) ! response to organic substance; GO:0003008 (0.06) ! system process; GO:0071711 (0.05) ! basement membrane organization; GO:0051716 (0.05) ! cellular response to stimulus; GO:0051276 (0.05) ! chromosome organization; GO:0051239 (0.05) ! regulation of multicellular organismal process; GO:0048583 (0.05) ! regulation of response to stimulus; GO:0048513 (0.05) ! animal organ development; GO:0044702 (0.05) ! single organism reproductive process; GO:0044271 (0.05) ! cellular nitrogen compound biosynthetic process; GO:0040017 (0.05) ! positive regulation of locomotion; GO:0031023 (0.05) ! microtubule organizing center organization; GO:0030036 (0.05) ! actin cytoskeleton organization; GO:0030031 (0.05) ! cell projection assembly; GO:0023051 (0.05) ! regulation of signaling; GO:0015031 (0.05) ! protein transport; GO:0010950 (0.05) ! positive regulation of endopeptidase activity; GO:0010646 (0.05) ! regulation of cell communication; GO:0009408 (0.05) ! response to heat; GO:0009059 (0.05) ! macromolecule biosynthetic process; GO:0008038 (0.05) ! neuron recognition; GO:0007346 (0.05) ! regulation of mitotic cell cycle; GO:0006464 (0.05) ! cellular protein modification process; GO:0006461 (0.05) ! protein complex assembly; GO:0006310 (0.05) ! DNA recombination; GO:0001764 (0.05) ! neuron migration; GO:0000003 (0.05) ! reproduction; GO:2000026 (0.04) ! regulation of multicellular organismal development; GO:1901990 (0.04) ! regulation of mitotic cell cycle phase transition; GO:0051983 (0.04) ! regulation of chromosome segregation; GO:0051788 (0.04) ! response to misfolded protein; GO:0051493 (0.04) ! regulation of cytoskeleton organization; GO:0051297 (0.04) ! centrosome organization; GO:0051130 (0.04) ! positive regulation of cellular component organization; GO:0048468 (0.04) ! cell development; GO:0045786 (0.04) ! negative regulation of cell cycle; GO:0044782 (0.04) ! cilium organization; GO:0043623 (0.04) ! cellular protein complex assembly; GO:0034645 (0.04) ! cellular macromolecule biosynthetic process; GO:0034613 (0.04) ! cellular protein localization; GO:0033554 (0.04) ! cellular response to stress; GO:0033044 (0.04) ! regulation of chromosome organization; GO:0031399 (0.04) ! regulation of protein modification process; GO:0030154 (0.04) ! cell differentiation; GO:0022603 (0.04) ! regulation of anatomical structure morphogenesis; GO:0019220 (0.04) ! regulation of phosphate metabolic process; GO:0010639 (0.04) ! negative regulation of organelle organization; GO:0009966 (0.04) ! regulation of signal transduction; GO:0007414 (0.04) ! axonal defasciculation; GO:0007131 (0.04) ! reciprocal meiotic recombination; GO:0007088 (0.04) ! regulation of mitotic nuclear division; GO:0006886 (0.04) ! intracellular protein transport; GO:0003341 (0.04) ! cilium movement; GO:0000075 (0.04) ! cell cycle checkpoint; GO:2000112 (0.03) ! regulation of cellular macromolecule biosynthetic process; GO:1902582 (0.03) ! single-organism intracellular transport; GO:1902531 (0.03) ! regulation of intracellular signal transduction; GO:1901564 (0.03) ! organonitrogen compound metabolic process; GO:0071103 (0.03) ! DNA conformation change; GO:0061024 (0.03) ! membrane organization; GO:0060285 (0.03) ! cilium-dependent cell motility; GO:0060284 (0.03) ! regulation of cell development; GO:0051293 (0.03) ! establishment of spindle localization; GO:0051049 (0.03) ! regulation of transport; GO:0050877 (0.03) ! neurological system process; GO:0048598 (0.03) ! embryonic morphogenesis; GO:0048193 (0.03) ! Golgi vesicle transport; GO:0044087 (0.03) ! regulation of cellular component biogenesis; GO:0042592 (0.03) ! homeostatic process; GO:0042384 (0.03) ! cilium assembly; GO:0034654 (0.03) ! nucleobase-containing compound biosynthetic process; GO:0033365 (0.03) ! protein localization to organelle; GO:0032970 (0.03) ! regulation of actin filament-based process; GO:0031032 (0.03) ! actomyosin structure organization; GO:0022604 (0.03) ! regulation of cell morphogenesis; GO:0019219 (0.03) ! regulation of nucleobase-containing compound metabolic process; GO:0009888 (0.03) ! tissue development; GO:0007610 (0.03) ! behavior; GO:0007411 (0.03) ! axon guidance; GO:0007094 (0.03) ! mitotic spindle assembly checkpoint; GO:0007059 (0.03) ! chromosome segregation; GO:0007051 (0.03) ! spindle organization; GO:0007030 (0.03) ! Golgi organization; GO:0006974 (0.03) ! cellular response to DNA damage stimulus; GO:0006936 (0.03) ! muscle contraction; GO:0006913 (0.03) ! nucleocytoplasmic transport; GO:0001934 (0.03) ! positive regulation of protein phosphorylation; GO:1903827 (0.02) ! regulation of cellular protein localization; GO:0090305 (0.02) ! nucleic acid phosphodiester bond hydrolysis; GO:0080134 (0.02) ! regulation of response to stress; GO:0072393 (0.02) ! microtubule anchoring at microtubule organizing center; GO:0070507 (0.02) ! regulation of microtubule cytoskeleton organization; GO:0070201 (0.02) ! regulation of establishment of protein localization; GO:0070192 (0.02) ! chromosome organization involved in meiotic cell cycle; GO:0061640 (0.02) ! cytoskeleton-dependent cytokinesis; GO:0060287 (0.02) ! epithelial cilium movement involved in determination of left/right asymmetry; GO:0051270 (0.02) ! regulation of cellular component movement; GO:0051240 (0.02) ! positive regulation of multicellular organismal process; GO:0051225 (0.02) ! spindle assembly; GO:0051050 (0.02) ! positive regulation of transport; GO:0050000 (0.02) ! chromosome localization; GO:0048858 (0.02) ! cell projection morphogenesis; GO:0045934 (0.02) ! negative regulation of nucleobase-containing compound metabolic process; GO:0044708 (0.02) ! single-organism behavior; GO:0044089 (0.02) ! positive regulation of cellular component biogenesis; GO:0036159 (0.02) ! inner dynein arm assembly; GO:0035239 (0.02) ! tube morphogenesis; GO:0035082 (0.02) ! axoneme assembly; GO:0032956 (0.02) ! regulation of actin cytoskeleton organization; GO:0032508 (0.02) ! DNA duplex unwinding; GO:0030048 (0.02) ! actin filament-based movement; GO:0022412 (0.02) ! cellular process involved in reproduction in multicellular organism; GO:0016337 (0.02) ! single organismal cell-cell adhesion; GO:0016233 (0.02) ! telomere capping; GO:0010975 (0.02) ! regulation of neuron projection development; GO:0010970 (0.02) ! establishment of localization by movement along microtubule; GO:0010720 (0.02) ! positive regulation of cell development; GO:0010638 (0.02) ! positive regulation of organelle organization; GO:0010628 (0.02) ! positive regulation of gene expression; GO:0010605 (0.02) ! negative regulation of macromolecule metabolic process; GO:0009968 (0.02) ! negative regulation of signal transduction; GO:0009967 (0.02) ! positive regulation of signal transduction; GO:0007600 (0.02) ! sensory perception; GO:0007389 (0.02) ! pattern specification process; GO:0007163 (0.02) ! establishment or maintenance of cell polarity; GO:0007154 (0.02) ! cell communication; GO:0007099 (0.02) ! centriole replication; GO:0007052 (0.02) ! mitotic spindle organization; GO:0007033 (0.02) ! vacuole organization; GO:0007020 (0.02) ! microtubule nucleation; GO:0007015 (0.02) ! actin filament organization; GO:0007004 (0.02) ! telomere maintenance via telomerase; GO:0006941 (0.02) ! striated muscle contraction; GO:0006897 (0.02) ! endocytosis; GO:0006468 (0.02) ! protein phosphorylation; GO:0006412 (0.02) ! translation; GO:0006355 (0.02) ! regulation of transcription, DNA-templated; GO:0003006 (0.02) ! developmental process involved in reproduction; GO:0002009 (0.02) ! morphogenesis of an epithelium; GO:0000724 (0.02) ! double-strand break repair via homologous recombination; GO:0000722 (0.02) ! telomere maintenance via recombination; GO:0000280 (0.02) ! nuclear division; GO:0000132 (0.02) ! establishment of mitotic spindle orientation; GO:2000241 (0.01) ! regulation of reproductive process; GO:2000027 (0.01) ! regulation of organ morphogenesis; GO:1905269 (0.01) ! positive regulation of chromatin organization; GO:1903923 (0.01) ! positive regulation of protein processing in phagocytic vesicle; GO:1903919 (0.01) ! negative regulation of actin filament severing; GO:1903008 (0.01) ! organelle disassembly; GO:1902532 (0.01) ! negative regulation of intracellular signal transduction; GO:1902017 (0.01) ! regulation of cilium assembly; GO:1901879 (0.01) ! regulation of protein depolymerization; GO:1901700 (0.01) ! response to oxygen-containing compound; GO:1900006 (0.01) ! positive regulation of dendrite development; GO:0098840 (0.01) ! protein transport along microtubule; GO:0098535 (0.01) ! de novo centriole assembly; GO:0090630 (0.01) ! activation of GTPase activity; GO:0090316 (0.01) ! positive regulation of intracellular protein transport; GO:0090307 (0.01) ! mitotic spindle assembly; GO:0090222 (0.01) ! centrosome-templated microtubule nucleation; GO:0090161 (0.01) ! Golgi ribbon formation; GO:0090068 (0.01) ! positive regulation of cell cycle process; GO:0090002 (0.01) ! establishment of protein localization to plasma membrane; GO:0072698 (0.01) ! protein localization to microtubule cytoskeleton; GO:0072659 (0.01) ! protein localization to plasma membrane; GO:0071902 (0.01) ! positive regulation of protein serine/threonine kinase activity; GO:0071495 (0.01) ! cellular response to endogenous stimulus; GO:0071310 (0.01) ! cellular response to organic substance; GO:0061572 (0.01) ! actin filament bundle organization; GO:0061025 (0.01) ! membrane fusion; GO:0060429 (0.01) ! epithelium development; GO:0060271 (0.01) ! cilium morphogenesis; GO:0055059 (0.01) ! asymmetric neuroblast division; GO:0055008 (0.01) ! cardiac muscle tissue morphogenesis; GO:0055003 (0.01) ! cardiac myofibril assembly; GO:0051988 (0.01) ! regulation of attachment of spindle microtubules to kinetochore; GO:0051893 (0.01) ! regulation of focal adhesion assembly; GO:0051646 (0.01) ! mitochondrion localization; GO:0051642 (0.01) ! centrosome localization; GO:0051495 (0.01) ! positive regulation of cytoskeleton organization; GO:0051494 (0.01) ! negative regulation of cytoskeleton organization; GO:0051492 (0.01) ! regulation of stress fiber assembly; GO:0051315 (0.01) ! attachment of mitotic spindle microtubules to kinetochore; GO:0051260 (0.01) ! protein homooligomerization; GO:0051241 (0.01) ! negative regulation of multicellular organismal process; GO:0051231 (0.01) ! spindle elongation; GO:0051093 (0.01) ! negative regulation of developmental process; GO:0051051 (0.01) ! negative regulation of transport; GO:0051028 (0.01) ! mRNA transport; GO:0050770 (0.01) ! regulation of axonogenesis; GO:0048812 (0.01) ! neuron projection morphogenesis; GO:0048790 (0.01) ! maintenance of presynaptic active zone structure; GO:0048789 (0.01) ! cytoskeletal matrix organization at active zone; GO:0048739 (0.01) ! cardiac muscle fiber development; GO:0048731 (0.01) ! system development; GO:0048666 (0.01) ! neuron development; GO:0048638 (0.01) ! regulation of developmental growth; GO:0048211 (0.01) ! Golgi vesicle docking; GO:0048167 (0.01) ! regulation of synaptic plasticity; GO:0047496 (0.01) ! vesicle transport along microtubule; GO:0046627 (0.01) ! negative regulation of insulin receptor signaling pathway; GO:0046330 (0.01) ! positive regulation of JNK cascade; GO:0046034 (0.01) ! ATP metabolic process; GO:0045995 (0.01) ! regulation of embryonic development; GO:0045936 (0.01) ! negative regulation of phosphate metabolic process; GO:0045931 (0.01) ! positive regulation of mitotic cell cycle; GO:0045893 (0.01) ! positive regulation of transcription, DNA-templated; GO:0045892 (0.01) ! negative regulation of transcription, DNA-templated; GO:0045785 (0.01) ! positive regulation of cell adhesion; GO:0045216 (0.01) ! cell-cell junction organization; GO:0045214 (0.01) ! sarcomere organization; GO:0045197 (0.01) ! establishment or maintenance of epithelial cell apical/basal polarity; GO:0045103 (0.01) ! intermediate filament-based process; GO:0045056 (0.01) ! transcytosis; GO:0044419 (0.01) ! interspecies interaction between organisms; GO:0044351 (0.01) ! macropinocytosis; GO:0043900 (0.01) ! regulation of multi-organism process; GO:0043405 (0.01) ! regulation of MAP kinase activity; GO:0043122 (0.01) ! regulation of I-kappaB kinase/NF-kappaB signaling; GO:0043086 (0.01) ! negative regulation of catalytic activity; GO:0043066 (0.01) ! negative regulation of apoptotic process; GO:0043009 (0.01) ! chordate embryonic development; GO:0042770 (0.01) ! signal transduction in response to DNA damage; GO:0042246 (0.01) ! tissue regeneration; GO:0042073 (0.01) ! intraciliary transport; GO:0040040 (0.01) ! thermosensory behavior; GO:0035295 (0.01) ! tube development; GO:0034454 (0.01) ! microtubule anchoring at centrosome; GO:0034329 (0.01) ! cell junction assembly; GO:0034067 (0.01) ! protein localization to Golgi apparatus; GO:0032507 (0.01) ! maintenance of protein location in cell; GO:0032271 (0.01) ! regulation of protein polymerization; GO:0032147 (0.01) ! activation of protein kinase activity; GO:0032006 (0.01) ! regulation of TOR signaling; GO:0031589 (0.01) ! cell-substrate adhesion; GO:0031532 (0.01) ! actin cytoskeleton reorganization; GO:0031400 (0.01) ! negative regulation of protein modification process; GO:0031338 (0.01) ! regulation of vesicle fusion; GO:0031175 (0.01) ! neuron projection development; GO:0031122 (0.01) ! cytoplasmic microtubule organization; GO:0031110 (0.01) ! regulation of microtubule polymerization or depolymerization; GO:0030866 (0.01) ! cortical actin cytoskeleton organization; GO:0030334 (0.01) ! regulation of cell migration; GO:0030317 (0.01) ! sperm motility; GO:0030241 (0.01) ! skeletal muscle myosin thick filament assembly; GO:0030216 (0.01) ! keratinocyte differentiation; GO:0030049 (0.01) ! muscle filament sliding; GO:0030010 (0.01) ! establishment of cell polarity; GO:0022008 (0.01) ! neurogenesis; GO:0019233 (0.01) ! sensory perception of pain; GO:0018193 (0.01) ! peptidyl-amino acid modification; GO:0018149 (0.01) ! peptide cross-linking; GO:0016570 (0.01) ! histone modification; GO:0016567 (0.01) ! protein ubiquitination; GO:0016482 (0.01) ! cytosolic transport; GO:0016319 (0.01) ! mushroom body development; GO:0016197 (0.01) ! endosomal transport; GO:0016070 (0.01) ! RNA metabolic process; GO:0016050 (0.01) ! vesicle organization; GO:0010824 (0.01) ! regulation of centrosome duplication; GO:0010770 (0.01) ! positive regulation of cell morphogenesis involved in differentiation; GO:0010631 (0.01) ! epithelial cell migration; GO:0010389 (0.01) ! regulation of G2/M transition of mitotic cell cycle; GO:0010243 (0.01) ! response to organonitrogen compound; GO:0009904 (0.01) ! chloroplast accumulation movement; GO:0009903 (0.01) ! chloroplast avoidance movement; GO:0009887 (0.01) ! organ morphogenesis; GO:0009880 (0.01) ! embryonic pattern specification; GO:0009798 (0.01) ! axis specification; GO:0009725 (0.01) ! response to hormone; GO:0009607 (0.01) ! response to biotic stimulus; GO:0009605 (0.01) ! response to external stimulus; GO:0009416 (0.01) ! response to light stimulus; GO:0008544 (0.01) ! epidermis development; GO:0008361 (0.01) ! regulation of cell size; GO:0008360 (0.01) ! regulation of cell shape; GO:0008344 (0.01) ! adult locomotory behavior; GO:0008335 (0.01) ! female germline ring canal stabilization; GO:0008284 (0.01) ! positive regulation of cell proliferation; GO:0008283 (0.01) ! cell proliferation; GO:0008105 (0.01) ! asymmetric protein localization; GO:0008088 (0.01) ! axo-dendritic transport; GO:0008064 (0.01) ! regulation of actin polymerization or depolymerization; GO:0007615 (0.01) ! anesthesia-resistant memory; GO:0007614 (0.01) ! short-term memory; GO:0007605 (0.01) ! sensory perception of sound; GO:0007522 (0.01) ! visceral muscle development; GO:0007519 (0.01) ! skeletal muscle tissue development; GO:0007507 (0.01) ! heart development; GO:0007476 (0.01) ! imaginal disc-derived wing morphogenesis; GO:0007420 (0.01) ! brain development; GO:0007368 (0.01) ! determination of left/right symmetry; GO:0007283 (0.01) ! spermatogenesis; GO:0007281 (0.01) ! germ cell development; GO:0007274 (0.01) ! neuromuscular synaptic transmission; GO:0007269 (0.01) ! neurotransmitter secretion; GO:0007266 (0.01) ! Rho protein signal transduction; GO:0007166 (0.01) ! cell surface receptor signaling pathway; GO:0007126 (0.01) ! meiotic nuclear division; GO:0007097 (0.01) ! nuclear migration; GO:0007080 (0.01) ! mitotic metaphase plate congression; GO:0007076 (0.01) ! mitotic chromosome condensation; GO:0007067 (0.01) ! mitotic nuclear division; GO:0007062 (0.01) ! sister chromatid cohesion; GO:0007058 (0.01) ! spindle assembly involved in female meiosis II; GO:0007041 (0.01) ! lysosomal transport; GO:0007005 (0.01) ! mitochondrion organization; GO:0006997 (0.01) ! nucleus organization; GO:0006914 (0.01) ! autophagy; GO:0006911 (0.01) ! phagocytosis, engulfment; GO:0006898 (0.01) ! receptor-mediated endocytosis; GO:0006888 (0.01) ! ER to Golgi vesicle-mediated transport; GO:0006606 (0.01) ! protein import into nucleus; GO:0006605 (0.01) ! protein targeting; GO:0006511 (0.01) ! ubiquitin-dependent protein catabolic process; GO:0006486 (0.01) ! protein glycosylation; GO:0006405 (0.01) ! RNA export from nucleus; GO:0006357 (0.01) ! regulation of transcription from RNA polymerase II promoter; GO:0006275 (0.01) ! regulation of DNA replication; GO:0006109 (0.01) ! regulation of carbohydrate metabolic process; GO:0003009 (0.01) ! skeletal muscle contraction; GO:0002682 (0.01) ! regulation of immune system process; GO:0002376 (0.01) ! immune system process; GO:0002064 (0.01) ! epithelial cell development; GO:0002027 (0.01) ! regulation of heart rate; GO:0001947 (0.01) ! heart looping; GO:0001822 (0.01) ! kidney development; GO:0001736 (0.01) ! establishment of planar polarity; GO:0001558 (0.01) ! regulation of cell growth; GO:0001525 (0.01) ! angiogenesis; GO:0000301 (0.01) ! retrograde transport, vesicle recycling within Golgi; GO:0000281 (0.01) ! mitotic cytokinesis; GO:0000278 (0.01) ! mitotic cell cycle; GO:0000086 (0.01) ! G2/M transition of mitotic cell cycle; GO:0000077 (0.01) ! DNA damage checkpoint; GO:0000070 (0.01) ! mitotic sister chromatid segregation; GO:0000045 (0.01) ! autophagosome assembly GO:0044424 (1.00) ! intracellular part; GO:0016020 (1.00) ! membrane; GO:0043234 (0.90) ! protein complex; GO:0044425 (0.86) ! membrane part; GO:0005942 (0.85) ! phosphatidylinositol 3-kinase complex; GO:0043226 (0.77) ! organelle; GO:0044444 (0.76) ! cytoplasmic part; GO:0043229 (0.75) ! intracellular organelle; GO:0005737 (0.74) ! cytoplasm; GO:0044446 (0.72) ! intracellular organelle part; GO:0005886 (0.69) ! plasma membrane; GO:0043227 (0.67) ! membrane-bounded organelle; GO:0043231 (0.66) ! intracellular membrane-bounded organelle; GO:0005829 (0.60) ! cytosol; GO:0044430 (0.47) ! cytoskeletal part; GO:0044421 (0.35) ! extracellular region part; GO:0005773 (0.34) ! vacuole; GO:0044428 (0.33) ! nuclear part; GO:0043232 (0.32) ! intracellular non-membrane-bounded organelle; GO:0042995 (0.32) ! cell projection; GO:0031982 (0.32) ! vesicle; GO:0031988 (0.31) ! membrane-bounded vesicle; GO:0005634 (0.30) ! nucleus; GO:0097651 (0.28) ! phosphatidylinositol 3-kinase complex, class I; GO:0044463 (0.26) ! cell projection part; GO:0031090 (0.26) ! organelle membrane; GO:0005764 (0.23) ! lysosome; GO:0031410 (0.21) ! cytoplasmic vesicle; GO:0016023 (0.20) ! cytoplasmic, membrane-bounded vesicle; GO:0042629 (0.18) ! mast cell granule; GO:0098588 (0.16) ! bounding membrane of organelle; GO:0044441 (0.16) ! ciliary part; GO:0005875 (0.16) ! microtubule associated complex; GO:0098805 (0.15) ! whole membrane; GO:0030027 (0.15) ! lamellipodium; GO:0005622 (0.15) ! intracellular; GO:0005944 (0.14) ! phosphatidylinositol 3-kinase complex, class IB; GO:0005943 (0.14) ! phosphatidylinositol 3-kinase complex, class IA; GO:0005871 (0.14) ! kinesin complex; GO:0070062 (0.13) ! extracellular exosome; GO:0044459 (0.13) ! plasma membrane part; GO:0005930 (0.13) ! axoneme; GO:0048471 (0.12) ! perinuclear region of cytoplasm; GO:0005615 (0.12) ! extracellular space; GO:0098590 (0.11) ! plasma membrane region; GO:0030141 (0.11) ! secretory granule; GO:0005929 (0.11) ! cilium; GO:0005794 (0.11) ! Golgi apparatus; GO:0072372 (0.10) ! primary cilium; GO:0034399 (0.10) ! nuclear periphery; GO:0031965 (0.10) ! nuclear membrane; GO:0030659 (0.10) ! cytoplasmic vesicle membrane; GO:0030496 (0.10) ! midbody; GO:0030139 (0.10) ! endocytic vesicle; GO:0005815 (0.10) ! microtubule organizing center; GO:0005768 (0.10) ! endosome; GO:0005730 (0.10) ! nucleolus; GO:0045335 (0.09) ! phagocytic vesicle; GO:0045171 (0.09) ! intercellular bridge; GO:0044427 (0.09) ! chromosomal part; GO:0035032 (0.09) ! phosphatidylinositol 3-kinase complex, class III; GO:0031526 (0.09) ! brush border membrane; GO:0030670 (0.09) ! phagocytic vesicle membrane; GO:0005813 (0.09) ! centrosome; GO:0005776 (0.09) ! autophagosome; GO:0005770 (0.09) ! late endosome; GO:0097458 (0.08) ! neuron part; GO:0005654 (0.08) ! nucleoplasm; GO:0044431 (0.07) ! Golgi apparatus part; GO:0044450 (0.06) ! microtubule organizing center part; GO:0044432 (0.06) ! endoplasmic reticulum part; GO:0043005 (0.06) ! neuron projection; GO:0005604 (0.06) ! basement membrane; GO:0000139 (0.06) ! Golgi membrane; GO:0099513 (0.05) ! polymeric cytoskeletal fiber; GO:0044454 (0.05) ! nuclear chromosome part; GO:0043025 (0.05) ! neuronal cell body; GO:0030054 (0.05) ! cell junction; GO:0012505 (0.05) ! endomembrane system; GO:0005856 (0.05) ! cytoskeleton; GO:0005814 (0.05) ! centriole; GO:0005783 (0.05) ! endoplasmic reticulum; GO:0005774 (0.05) ! vacuolar membrane; GO:0005739 (0.05) ! mitochondrion; GO:0044449 (0.04) ! contractile fiber part; GO:0031932 (0.04) ! TORC2 complex; GO:0031931 (0.04) ! TORC1 complex; GO:0030425 (0.04) ! dendrite; GO:0016605 (0.04) ! PML body; GO:0005789 (0.04) ! endoplasmic reticulum membrane; GO:0005765 (0.04) ! lysosomal membrane; GO:0005741 (0.04) ! mitochondrial outer membrane; GO:0000922 (0.04) ! spindle pole; GO:0098791 (0.03) ! Golgi subcompartment; GO:0098687 (0.03) ! chromosomal region; GO:0070161 (0.03) ! anchoring junction; GO:0044448 (0.03) ! cell cortex part; GO:0030529 (0.03) ! intracellular ribonucleoprotein complex; GO:0016459 (0.03) ! myosin complex; GO:0016021 (0.03) ! integral component of membrane; GO:0005938 (0.03) ! cell cortex; GO:0005911 (0.03) ! cell-cell junction; GO:0005874 (0.03) ! microtubule; GO:0005819 (0.03) ! spindle; GO:0005694 (0.03) ! chromosome; GO:0005643 (0.03) ! nuclear pore; GO:0000785 (0.03) ! chromatin; GO:0000776 (0.03) ! kinetochore; GO:1990752 (0.02) ! microtubule end; GO:0099738 (0.02) ! cell cortex region; GO:0097539 (0.02) ! ciliary transition fiber; GO:0044456 (0.02) ! synapse part; GO:0035861 (0.02) ! site of double-strand break; GO:0031985 (0.02) ! Golgi cisterna; GO:0030870 (0.02) ! Mre11 complex; GO:0030176 (0.02) ! integral component of endoplasmic reticulum membrane; GO:0016460 (0.02) ! myosin II complex; GO:0005912 (0.02) ! adherens junction; GO:0005840 (0.02) ! ribosome; GO:0005801 (0.02) ! cis-Golgi network; GO:0005635 (0.02) ! nuclear envelope; GO:0000795 (0.02) ! synaptonemal complex; GO:0000794 (0.02) ! condensed nuclear chromosome; GO:0000790 (0.02) ! nuclear chromatin; GO:0000784 (0.02) ! nuclear chromosome, telomeric region; GO:1990316 (0.01) ! ATG1/ULK1 kinase complex; GO:0098589 (0.01) ! membrane region; GO:0097431 (0.01) ! mitotic spindle pole; GO:0097223 (0.01) ! sperm part; GO:0072686 (0.01) ! mitotic spindle; GO:0061689 (0.01) ! tricellular tight junction; GO:0051233 (0.01) ! spindle midzone; GO:0048786 (0.01) ! presynaptic active zone; GO:0045180 (0.01) ! basal cortex; GO:0045179 (0.01) ! apical cortex; GO:0045177 (0.01) ! apical part of cell; GO:0044291 (0.01) ! cell-cell contact zone; GO:0043256 (0.01) ! laminin complex; GO:0042734 (0.01) ! presynaptic membrane; GO:0036449 (0.01) ! microtubule minus-end; GO:0036064 (0.01) ! ciliary basal body; GO:0035371 (0.01) ! microtubule plus-end; GO:0034451 (0.01) ! centriolar satellite; GO:0034045 (0.01) ! pre-autophagosomal structure membrane; GO:0033596 (0.01) ! TSC1-TSC2 complex; GO:0033267 (0.01) ! axon part; GO:0032982 (0.01) ! myosin filament; GO:0032154 (0.01) ! cleavage furrow; GO:0031594 (0.01) ! neuromuscular junction; GO:0031252 (0.01) ! cell leading edge; GO:0031012 (0.01) ! extracellular matrix; GO:0030992 (0.01) ! intraciliary transport particle B; GO:0030893 (0.01) ! meiotic cohesin complex; GO:0030863 (0.01) ! cortical cytoskeleton; GO:0030662 (0.01) ! coated vesicle membrane; GO:0030426 (0.01) ! growth cone; GO:0030424 (0.01) ! axon; GO:0030133 (0.01) ! transport vesicle; GO:0030018 (0.01) ! Z disc; GO:0030017 (0.01) ! sarcomere; GO:0030016 (0.01) ! myofibril; GO:0019898 (0.01) ! extrinsic component of membrane; GO:0016363 (0.01) ! nuclear matrix; GO:0015630 (0.01) ! microtubule cytoskeleton; GO:0015629 (0.01) ! actin cytoskeleton; GO:0008305 (0.01) ! integrin complex; GO:0005925 (0.01) ! focal adhesion; GO:0005913 (0.01) ! cell-cell adherens junction; GO:0005884 (0.01) ! actin filament; GO:0005882 (0.01) ! intermediate filament; GO:0005881 (0.01) ! cytoplasmic microtubule; GO:0005876 (0.01) ! spindle microtubule; GO:0005859 (0.01) ! muscle myosin complex; GO:0005826 (0.01) ! actomyosin contractile ring; GO:0005802 (0.01) ! trans-Golgi network; GO:0005795 (0.01) ! Golgi stack; GO:0005769 (0.01) ! early endosome; GO:0005605 (0.01) ! basal lamina; GO:0005576 (0.01) ! extracellular region; GO:0001726 (0.01) ! ruffle; GO:0001725 (0.01) ! stress fiber; GO:0001533 (0.01) ! cornified envelope; GO:0000940 (0.01) ! condensed chromosome outer kinetochore; GO:0000778 (0.01) ! condensed nuclear chromosome kinetochore; GO:0000775 (0.01) ! chromosome, centromeric region; GO:0000242 (0.01) ! pericentriolar material; GO:0000151 (0.01) ! ubiquitin ligase complex; GO:0000137 (0.01) ! Golgi cis cisterna GO:0005515 ! protein binding 5 GO:0005515 ! protein binding 82101460-82212830 (17q25.3) High: stomach 2 (glandular cells);stomach 1 (glandular cells);seminal vesicle (glandular cells);colon (endothelial cells; glandular cells);gallbladder (glandular cells);esophagus (squamous epithelial cells);kidney (cells in glomeruli; cells in tubules);testis (cells in seminiferous ducts);tonsil (squamous epithelial cells);vagina (squamous epithelial cells);epididymis (glandular cells);adrenal gland (glandular cells);endometrium 1 (glandular cells);thyroid gland (glandular cells);salivary gland (glandular cells);heart muscle (myocytes);cerebral cortex (neuronal cells);lymph node (non-germinal center cells);placenta (trophoblastic cells);bronchus (respiratory epithelial cells);parathyroid gland (glandular cells);urinary bladder (urothelial cells);appendix (glandular cells);liver (bile duct cells);rectum (glandular cells);prostate (glandular cells);cervix, uterine (glandular cells; squamous epithelial cells);duodenum (glandular cells);cerebellum (cells in molecular layer; Purkinje cells);fallopian tube (glandular cells);skin 2 (epidermal cells);small intestine (glandular cells);nasopharynx (respiratory epithelial cells);oral mucosa (squamous epithelial cells);skin 1 (keratinocytes; melanocytes);breast (glandular cells; myoepithelial cells);Medium: colon (peripheral nerve/ganglion);smooth muscle (smooth muscle cells);testis (Leydig cells);caudate (neuronal cells);tonsil (germinal center cells; non-germinal center cells);endometrium 1 (cells in endometrial stroma);endometrium 2 (cells in endometrial stroma; glandular cells);cerebral cortex (endothelial cells);lymph node (germinal center cells);hippocampus (neuronal cells);skeletal muscle (myocytes);appendix (lymphoid tissue);breast (adipocytes);pancreas (exocrine glandular cells; islets of Langerhans);spleen (cells in white pulp);bone marrow (hematopoietic cells);soft tissue 2 (adipocytes; fibroblasts);soft tissue 1 (adipocytes; fibroblasts; peripheral nerve);lung (macrophages; pneumocytes);ovary (ovarian stroma cells);skin 1 (fibroblasts; Langerhans);liver (hepatocytes);Low: cerebellum (cells in granular layer);hippocampus (glial cells);caudate (glial cells);spleen (cells in red pulp);soft tissue 1 (chondrocytes);soft tissue 2 (peripheral nerve);ovary (follicle cells);cerebral cortex (glial cells); Thyroid: 27.31; Brain - Cerebellum: 23.59; Pituitary: 22.78; Testis: 21.43; Brain - Cerebellar Hemisphere: 20.41; Prostate: 19.98; Ovary: 19.02; Uterus: 18.12; Fallopian Tube: 17.73; Cervix - Endocervix: 13.96; Lung: 13.74; Cervix - Ectocervix: 13.68; Nerve - Tibial: 13.09; Minor Salivary Gland: 12.21; Bladder: 12.18; Breast - Mammary Tissue: 11.65; Colon - Sigmoid: 10.78; Vagina: 9.88; Spleen: 9.00; Cells - Transformed fibroblasts: 8.94; Small Intestine - Terminal Ileum: 8.89; Adrenal Gland: 8.88; Kidney - Cortex: 8.82; Stomach: 8.39; Esophagus - Muscularis: 7.86; Esophagus - Gastroesophageal Junction: 7.77; Colon - Transverse: 7.59; Adipose - Subcutaneous: 7.51; Brain - Cortex: 7.32; Skin - Not Sun Exposed (Suprapubic): 7.03; Skin - Sun Exposed (Lower leg): 6.98; Artery - Coronary: 6.81; Artery - Aorta: 6.55; Adipose - Visceral (Omentum): 6.44; Brain - Frontal Cortex (BA9): 5.85; Cells - EBV-transformed lymphocytes: 5.77; Brain - Nucleus accumbens (basal ganglia): 5.52; Pancreas: 5.45; Whole Blood: 5.44; Artery - Tibial: 5.33; Brain - Caudate (basal ganglia): 4.99; Esophagus - Mucosa: 4.31; Brain - Hypothalamus: 4.23; Brain - Anterior cingulate cortex (BA24): 4.18; Brain - Putamen (basal ganglia): 4.11; Liver: 3.67; Brain - Hippocampus: 3.26; Brain - Amygdala: 3.04; Brain - Spinal cord (cervical c-1): 3.03; Heart - Atrial Appendage: 2.95; Brain - Substantia nigra: 2.35; Muscle - Skeletal: 2.22; Heart - Left Ventricle: 1.47; MLPLGSEPALNELLLRKEEEWRALQAHRTQLQEAALQDTRSQLEEAQGKLRCLQEDFVYNLQVLEERDLELERYDAAFAQAREWEEARRAEVSELKIEAAKLRQALAREARKVEELQQQQQLAFQEHRLELERVHSDKNGEIDHHREQYENLKWTLERKLEELDGELALQRQELLLEFESKMRKREHEFRLQADNMSNTALSRELKVKLLHKELEALKEAGAKAAESLQRAEATNAELERKLQSRAGELQDLEAMSRARVKDLEDKLHSVQLTRKKEEETFKRKHEELDRLAREKDAVLVAVKGAHVEQLQELQTRVLELQAHCETLEAQLRRAEWRQADTAKEKDAAIDQLREDASTVKSAWDAQIAQLSKEMVSRDLQIQTLQEEEVKLKAQVARSQQDIERYKQQLSLAVERERSLERDQVQLGLDWQRRCDDIERDQIQKSEALIQGLSMAKSQVAAKLQETEQALQEQEVVLKAVTLERDQAVQALRMHGLPRPGAQMLLRQHEEEISKDFPSSEIQRLREQNTSLRNAIAQMRKEMEALSHQIPPPIQTAAESTDANQPDPEAGGDAATPDYVLALEAEIRTLKHKFKTLEKHLEDVLDPLKMSSPHAESQPSVRTSTETTGGSAQAGQAGGSVQAGQAGGSVQAGPVSSGLALRKLGDRVQLLNLLVTRLRQKVLREPLEPAALQRELPREVDQVHLEVLELRKQVAELGKHLRIAQHGGAEPSGRKQPPASDAVALGREQDAKSAEDEAPSRHLGKHQPRSAQVGSRLDALQGPKTQHSIHTVTCKSPRQKEDRSPKPPQAPQHPEEHGRQSHSSSSFASGTLQDMWRLLDLGSSPSGVTSQGDSTPELPAPPAADRRPVKMQAGIATPGMKTAAQAKAKTTGASRSHPAKAKGCQRPPKIRNYNIMD C17orf62 Uncharacterized protein C17orf62 CQ062_HUMAN (Q9BQA9-1) GO:0035639 (0.57) ! purine ribonucleoside triphosphate binding; GO:0032559 (0.57) ! adenyl ribonucleotide binding; GO:0032550 (0.57) ! purine ribonucleoside binding; GO:0051427 (0.37) ! hormone receptor binding; GO:0031701 (0.37) ! angiotensin receptor binding; GO:0005126 (0.37) ! cytokine receptor binding; GO:0004672 (0.37) ! protein kinase activity GO:0044351 (0.83) ! macropinocytosis; GO:0048870 (0.32) ! cell motility; GO:0048869 (0.32) ! cellular developmental process; GO:0046777 (0.32) ! protein autophosphorylation; GO:0018108 (0.32) ! peptidyl-tyrosine phosphorylation; GO:0008283 (0.32) ! cell proliferation; GO:0007165 (0.32) ! signal transduction; GO:0006955 (0.32) ! immune response; GO:0006952 (0.32) ! defense response GO:0044424 (1.00) ! intracellular part; GO:0044446 (0.95) ! intracellular organelle part; GO:0043226 (0.95) ! organelle; GO:0043229 (0.89) ! intracellular organelle; GO:0044444 (0.84) ! cytoplasmic part; GO:0043232 (0.79) ! intracellular non-membrane-bounded organelle; GO:0044430 (0.74) ! cytoskeletal part; GO:0043227 (0.74) ! membrane-bounded organelle; GO:0005856 (0.74) ! cytoskeleton; GO:0005737 (0.74) ! cytoplasm; GO:0043231 (0.68) ! intracellular membrane-bounded organelle; GO:0005874 (0.68) ! microtubule; GO:0005829 (0.68) ! cytosol; GO:0005871 (0.63) ! kinesin complex; GO:0016020 (0.53) ! membrane; GO:0005634 (0.53) ! nucleus; GO:0005815 (0.42) ! microtubule organizing center; GO:0005819 (0.37) ! spindle; GO:0005876 (0.32) ! spindle microtubule; GO:0044425 (0.26) ! membrane part; GO:0005813 (0.26) ! centrosome; GO:0044459 (0.21) ! plasma membrane part; GO:0044428 (0.21) ! nuclear part; GO:0042995 (0.21) ! cell projection; GO:0044448 (0.16) ! cell cortex part; GO:0044441 (0.16) ! ciliary part; GO:0044437 (0.16) ! vacuolar part; GO:0031234 (0.16) ! extrinsic component of cytoplasmic side of plasma membrane; GO:0015630 (0.16) ! microtubule cytoskeleton; GO:0005901 (0.16) ! caveola; GO:0005881 (0.16) ! cytoplasmic microtubule; GO:0000776 (0.16) ! kinetochore; GO:1990498 (0.11) ! mitotic spindle microtubule; GO:0097542 (0.11) ! ciliary tip; GO:0097458 (0.11) ! neuron part; GO:0072687 (0.11) ! meiotic spindle; GO:0070062 (0.11) ! extracellular exosome; GO:0048471 (0.11) ! perinuclear region of cytoplasm; GO:0035371 (0.11) ! microtubule plus-end; GO:0031904 (0.11) ! endosome lumen; GO:0030981 (0.11) ! cortical microtubule cytoskeleton; GO:0016363 (0.11) ! nuclear matrix; GO:0012505 (0.11) ! endomembrane system; GO:0005929 (0.11) ! cilium; GO:0005873 (0.11) ! plus-end kinesin complex; GO:0005872 (0.11) ! minus-end kinesin complex; GO:0005816 (0.11) ! spindle pole body; GO:0005654 (0.11) ! nucleoplasm; GO:0000922 (0.11) ! spindle pole; GO:0000777 (0.11) ! condensed chromosome kinetochore; GO:1990811 (0.05) ! Msd1-Wdr8-Pkl1 complex; GO:1990023 (0.05) ! mitotic spindle midzone; GO:1904115 (0.05) ! axon cytoplasm; GO:0098793 (0.05) ! presynapse; GO:0097228 (0.05) ! sperm principal piece; GO:0072686 (0.05) ! mitotic spindle; GO:0072372 (0.05) ! primary cilium; GO:0044732 (0.05) ! mitotic spindle pole body; GO:0043005 (0.05) ! neuron projection; GO:0030990 (0.05) ! intraciliary transport particle; GO:0030496 (0.05) ! midbody; GO:0030478 (0.05) ! actin cap; GO:0016939 (0.05) ! kinesin II complex; GO:0016021 (0.05) ! integral component of membrane; GO:0009570 (0.05) ! chloroplast stroma; GO:0009507 (0.05) ! chloroplast; GO:0005828 (0.05) ! kinetochore microtubule; GO:0005774 (0.05) ! vacuolar membrane; GO:0005773 (0.05) ! vacuole; GO:0005739 (0.05) ! mitochondrion; GO:0005730 (0.05) ! nucleolus; GO:0005694 (0.05) ! chromosome; GO:0001726 (0.05) ! ruffle; GO:0000778 (0.05) ! condensed nuclear chromosome kinetochore; GO:0000775 (0.05) ! chromosome, centromeric region GO:0005515 ! protein binding GO:0016020 ! membrane; GO:0016021 ! integral component of membrane 2 GO:0005515 ! protein binding 82442589-82450829 (17q25.3) Whole Blood: 173.20; Spleen: 169.90; Cells - EBV-transformed lymphocytes: 118.10; Cervix - Endocervix: 65.07; Lung: 59.58; Prostate: 58.26; Nerve - Tibial: 57.70; Fallopian Tube: 52.90; Uterus: 49.19; Bladder: 48.54; Small Intestine - Terminal Ileum: 48.16; Ovary: 46.64; Thyroid: 43.98; Adipose - Subcutaneous: 43.76; Cervix - Ectocervix: 43.38; Artery - Aorta: 42.93; Artery - Coronary: 42.37; Breast - Mammary Tissue: 42.05; Pituitary: 41.88; Cells - Transformed fibroblasts: 41.58; Adipose - Visceral (Omentum): 39.31; Brain - Spinal cord (cervical c-1): 37.67; Vagina: 37.64; Minor Salivary Gland: 33.43; Artery - Tibial: 33.41; Colon - Transverse: 32.48; Adrenal Gland: 31.39; Esophagus - Muscularis: 31.15; Colon - Sigmoid: 30.67; Kidney - Cortex: 30.40; Esophagus - Gastroesophageal Junction: 30.18; Stomach: 30.14; Skin - Sun Exposed (Lower leg): 29.32; Esophagus - Mucosa: 28.81; Liver: 27.49; Skin - Not Sun Exposed (Suprapubic): 27.34; Testis: 27.24; Brain - Cerebellum: 26.85; Brain - Cerebellar Hemisphere: 23.45; Brain - Substantia nigra: 21.93; Brain - Hypothalamus: 20.80; Brain - Cortex: 20.49; Brain - Nucleus accumbens (basal ganglia): 20.29; Brain - Caudate (basal ganglia): 19.67; Brain - Putamen (basal ganglia): 18.18; Brain - Frontal Cortex (BA9): 18.09; Pancreas: 17.96; Brain - Amygdala: 16.34; Brain - Hippocampus: 16.02; Brain - Anterior cingulate cortex (BA24): 13.66; Heart - Atrial Appendage: 13.43; Heart - Left Ventricle: 8.99; Muscle - Skeletal: 6.51; MYLQVETRTSSRLHLKRAPGIRSWSLLVGILSIGLAAAYYSGDSLGWKLFYVTGCLFVAVQNLEDWEEAIFDKSTGKVVLKTFSLYKKLLTLFRAGHDQVVVLLHDVRDVSVEEEKVRYFGKGYMVVLRLATGFSHPLTQSAVMGHRSDVEAIAKLITSFLELHCLESPTELSQSSDSEAGDPASQS