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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	B1 bradykinin receptor
Species	Rattus norvegicus (Rat)
Gene	Bdkrb1
Synonym	KB1 bradykinin receptor BKR1 BK-1 receptor B1R B1BKR B1 receptor Kinin B1 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	337
Amino acid sequence	MASEVLLELQPSNRSLQAPANITSCESALEDWDLLYRVLPGFVITICFFGLLGNLLVLSFFLLPWRQWWWQQRQRQQRLTIAEIYLANLAASDLVFVLGLPFWAENIGNRFNWPFGTDLCRVVSGVIKANLFVSIFLVVAISQDRYRLLVYPMTSWGYRRRRQAQATCLLIWVAGGLLSIPTFLLRSVKVVPDLNVSACILLFPHEAWHFARMVELNVLGFLLPVTAIIFFNYHILASLRGQKEASRTRCGGPKGSKTTGLILTLVASFLVCWCPYHFFAFLDFLVQVRVIQDCSWKEITDLGLQLANFFAFVNSCLNPLIYVFAGRLLKTRVLGTL
UniProt	P97583
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4613
IUPHAR	41
DrugBank	N/A

Ligand

Name	CHEMBL320458
Molecular formula	C41H70N10O8
IUPAC name	(2S)-2-[[(2S)-1-[(2S)-2-[12-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]dodecanoylamino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Molecular weight	831.073
Hydrogen bond acceptor	11
Hydrogen bond donor	10
XlogP	-1.0
Synonyms	[12-(Lys-Arg-Amino-)dodecanoyl]-Ser-Pro-Phe-OH
Inchi Key	HEYQLRQWKZCACH-LJADHVKFSA-N
Inchi ID	InChI=1S/C41H70N10O8/c42-23-13-12-19-30(43)36(54)49-31(20-15-25-47-41(44)45)37(55)46-24-14-7-5-3-1-2-4-6-11-22-35(53)48-33(28-52)39(57)51-26-16-21-34(51)38(56)50-32(40(58)59)27-29-17-9-8-10-18-29/h8-10,17-18,30-34,52H,1-7,11-16,19-28,42-43H2,(H,46,55)(H,48,53)(H,49,54)(H,50,56)(H,58,59)(H4,44,45,47)/t30-,31-,32-,33-,34-/m0/s1
PubChem CID	10373299
ChEMBL	CHEMBL320458
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
pD2	6.0 -	PMID11170638	ChEMBL

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