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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	B2 bradykinin receptor
Species	Rattus norvegicus (Rat)
Gene	Bdkrb2
Synonym	B2 receptor B2BKR B2BRA BK-2 receptor BK2R bradykinin receptor B2R [ Show all ]
Disease	N/A for non-human GPCRs
Length	396
Amino acid sequence	MDTRSSLCPKTQAVVAVFWGPGCHLSTCIEMFNITTQALGSAHNGTFSEVNCPDTEWWSWLNAIQAPFLWVLFLLAALENIFVLSVFCLHKTNCTVAEIYLGNLAAADLILACGLPFWAITIANNFDWLFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWSCTLLLSSPMLVFRTMKDYREEGHNVTACVIVYPSRSWEVFTNMLLNLVGFLLPLSIITFCTVRIMQVLRNNEMKKFKEVQTEKKATVLVLAVLGLFVLCWFPFQISTFLDTLLRLGVLSGCWNERAVDIVTQISSYVAYSNSCLNPLVYVIVGKRFRKKSREVYQAICRKGGCMGESVQMENSMGTLRTSISVDRQIHKLQDWAGNKQ
UniProt	P25023
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2501
IUPHAR	42
DrugBank	N/A

Ligand

Name	CHEMBL165238
Molecular formula	C15H15N3O3
IUPAC name	1-benzyl-3-[(2-nitrophenyl)methyl]urea
Molecular weight	285.303
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.6
Synonyms	1-Benzyl-3-(2-nitro-benzyl)-urea DTXSID80571480 1-Benzyl-3-(2-nitrobenzyl)urea N-Benzyl-N'-[(2-nitrophenyl)methyl]urea BDBM50085697 CTK0A3637 188911-50-4 Urea, N-[(2-nitrophenyl)methyl]-N'-(phenylmethyl)- [ Show all ]
Inchi Key	IAZPBCJVNLDDIU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H15N3O3/c19-15(16-10-12-6-2-1-3-7-12)17-11-13-8-4-5-9-14(13)18(20)21/h1-9H,10-11H2,(H2,16,17,19)
PubChem CID	15323518
ChEMBL	CHEMBL165238
IUPHAR	N/A
BindingDB	50085697
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<100000.0 nM	PMID10715143	BindingDB,ChEMBL

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