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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptide Y receptor type 5
Species	Mus musculus (Mouse)
Gene	Npy5r
Synonym	food intake receptor neuropeptide Y receptor type 5 NPY-Y5 receptor NPY5-R NPYY5-R Y5 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	466
Amino acid sequence	MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVKPEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
UniProt	O70342
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3802
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL2070144
Molecular formula	C23H21NO2S
IUPAC name	2-(3-phenylphenyl)-5-propylsulfonyl-1H-indole
Molecular weight	375.486
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.5
Synonyms	BDBM50390237
Inchi Key	IMDBJTRJWRUFRG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H21NO2S/c1-2-13-27(25,26)21-11-12-22-20(15-21)16-23(24-22)19-10-6-9-18(14-19)17-7-4-3-5-8-17/h3-12,14-16,24H,2,13H2,1H3
PubChem CID	70688846
ChEMBL	CHEMBL2070144
IUPHAR	N/A
BindingDB	50390237
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	11.6 nM	PMID22853998	ChEMBL
IC50	12.0 nM	PMID22853998	BindingDB

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