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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Prostaglandin D2 receptor
Species	Mus musculus (Mouse)
Gene	Ptgdr
Synonym	prostanoid DP receptor-like Prostanoid DP receptor prostaglandin D2 receptor (DP) PGD2 receptor PGD receptor DP1 receptor DP1 PTGDR1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	357
Amino acid sequence	MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
UniProt	P70263
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3933
IUPHAR	338
DrugBank	N/A

Ligand

Name	CHEMBL1819624
Molecular formula	C25H22ClFN2O5
IUPAC name	2-[5-[[2-chloro-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]-2-fluorophenyl]acetic acid
Molecular weight	484.908
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.5
Synonyms	BDBM50351497 SCHEMBL2194481
Inchi Key	INJUIJYGLDYSDZ-SFHVURJKSA-N
Inchi ID	InChI=1S/C25H22ClFN2O5/c1-29-13-18(34-23-5-3-2-4-22(23)29)14-33-17-7-8-19(20(26)12-17)25(32)28-16-6-9-21(27)15(10-16)11-24(30)31/h2-10,12,18H,11,13-14H2,1H3,(H,28,32)(H,30,31)/t18-/m0/s1
PubChem CID	56668529
ChEMBL	CHEMBL1819624
IUPHAR	N/A
BindingDB	50351497
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	50.0 nM	PMID21885288	BindingDB,ChEMBL
Ki	25.0 nM	PMID21885288	BindingDB,ChEMBL

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