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Name | G-protein coupled receptor 55 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR55 |
Synonym | GPR55 |
Disease | N/A |
Length | 319 |
Amino acid sequence | MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG |
UniProt | Q9Y2T6 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9Y2T6 |
3D structure model | This predicted structure model is from GPCR-EXP Q9Y2T6. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1075322 |
IUPHAR | 109 |
DrugBank | BE0005802 |
Name | CHEMBL2181543 |
---|---|
Molecular formula | C27H32O4 |
IUPAC name | 7-(1-butylcyclopentyl)-5-methoxy-3-[(2-methoxyphenyl)methyl]chromen-2-one |
Molecular weight | 420.549 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 0 |
XlogP | 7.9 |
Synonyms | BDBM50398217 |
Inchi Key | JDYPQQKFCAAXRZ-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C27H32O4/c1-4-5-12-27(13-8-9-14-27)21-17-24(30-3)22-16-20(26(28)31-25(22)18-21)15-19-10-6-7-11-23(19)29-2/h6-7,10-11,16-18H,4-5,8-9,12-15H2,1-3H3 |
PubChem CID | 70678102 |
ChEMBL | CHEMBL2181543 |
IUPHAR | N/A |
BindingDB | 50398217 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 30.0 % | PMID23679955 | ChEMBL |
IC50 | <10000.0 nM | PMID23679955 | BindingDB,ChEMBL |
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