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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 5
Species	Homo sapiens (Human)
Gene	LPAR5
Synonym	G-protein coupled receptor 92 LPAR5 LPA5 receptor LPA-5 LPA receptor 5 G protein-coupled receptor 92 GPR92 G-protein coupled receptor 93 GPR93 [ Show all ]
Disease	N/A
Length	372
Amino acid sequence	MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
UniProt	Q9H1C0
Protein Data Bank	N/A
GPCR-HGmod model	Q9H1C0
3D structure model	This predicted structure model is from GPCR-EXP Q9H1C0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5700
IUPHAR	124
DrugBank	N/A

Ligand

Name	4-[5-(3-nitrophenoxy)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]butanoic acid
Molecular formula	C18H14N2O7
IUPAC name	4-[5-(3-nitrophenoxy)-1,3-dioxoisoindol-2-yl]butanoic acid
Molecular weight	370.317
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.1
Synonyms	AKOS003334518 SR-01000281923 HMS2642D15 ZINC5065382 4-[5-(3-nitrophenoxy)-1,3-dioxoisoindol-2-yl]butanoic acid MolPort-001-578-620 SR-01000281923-1 MCULE-9754810652 AC1LP2UU SMR000300346 CHEMBL604273 STK266456 MLS000690484 [ Show all ]
Inchi Key	AUPJYDYZHVQFBI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H14N2O7/c21-16(22)5-2-8-19-17(23)14-7-6-13(10-15(14)18(19)24)27-12-4-1-3-11(9-12)20(25)26/h1,3-4,6-7,9-10H,2,5,8H2,(H,21,22)
PubChem CID	1300229
ChEMBL	CHEMBL604273
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	18.0 %	PMID19800804	ChEMBL

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