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GPCR

NameGalanin receptor type 2
SpeciesHomo sapiens (Human)
GeneGALR2
SynonymGAL2 receptor
GAL2-R
GALNR2
GALR-2
DiseaseN/A
Length387
Amino acid sequenceMNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
UniProtO43603
Protein Data BankN/A
GPCR-HGmod modelO43603
3D structure modelThis predicted structure model is from GPCR-EXP O43603.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3176
IUPHAR244
DrugBankN/A

Ligand

NameCHEMBL571758
Molecular formulaC14H11BrClN3
IUPAC name7-bromo-N-(3-chlorophenyl)-1-methylpyrrolo[3,2-c]pyridin-4-amine
Molecular weight336.617
Hydrogen bond acceptor2
Hydrogen bond donor1
XlogP4.1
SynonymsSCHEMBL3993495
JFIOFXPCIFBCIW-UHFFFAOYSA-N
(7-Bromo-1-methyl-1H-pyrrolo[3,2-c]pyridin-4-yl)-(3-chloro-phenyl)-amine
Inchi KeyJFIOFXPCIFBCIW-UHFFFAOYSA-N
Inchi IDInChI=1S/C14H11BrClN3/c1-19-6-5-11-13(19)12(15)8-17-14(11)18-10-4-2-3-9(16)7-10/h2-8H,1H3,(H,17,18)
PubChem CID45487767
ChEMBLCHEMBL571758
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
Activity>10.0 %PMID19743867ChEMBL

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