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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-3 adrenergic receptor
Species	Rattus norvegicus (Rat)
Gene	Adrb3
Synonym	beta3-adrenoceptor beta3-adrenergic receptor Beta-3 adrenoreceptor Beta-3 adrenoceptor ADRB beta 3-AR atypical beta-adrenoceptor adrenergic receptor Adrb-3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	400
Amino acid sequence	MAPWPHKNGSLAFWSDAPTLDPSAANTSGLPGVPWAAALAGALLALATVGGNLLVITAIARTPRLQTITNVFVTSLATADLVVGLLVMPPGATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSATVSFAPIMSQWWRVGADAEAQECHSNPRCCSFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVAKRQRRLLRRELGRFPPEESPRSPSRSPSPATVGTPTASDGVPSCGRRPARLLPLGEHRALRTLGLIMGIFSLCWLPFFLANVLRALVGPSLVPSGVFIALNWLGYANSAFNPLIYCRSPDFRDAFRRLLCSYGGRGPEEPRVVTFPASPVASRQNSPLNRFDGYEGERPFPT
UniProt	P26255
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4031
IUPHAR	30
DrugBank	N/A

Ligand

Name	CHEMBL49650
Molecular formula	C21H27NO5
IUPAC name	methyl 2-[4-[2-[(2-hydroxy-3-phenoxypropyl)amino]propyl]phenoxy]acetate
Molecular weight	373.449
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.1
Synonyms	SCHEMBL9684241 [4-[2-(2-Hydroxy-3-phenoxypropylamino)propyl]phenoxy]acetic acid methyl ester
Inchi Key	KAVTURIWLISQMG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H27NO5/c1-16(22-13-18(23)14-26-19-6-4-3-5-7-19)12-17-8-10-20(11-9-17)27-15-21(24)25-2/h3-11,16,18,22-23H,12-15H2,1-2H3
PubChem CID	15034340
ChEMBL	CHEMBL49650
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ED50	0.003 mg.kg-1	PMID1350309	ChEMBL
ED50	0.007 mg.kg-1	PMID1350309	ChEMBL
SI	15.7 beats min-1	PMID1350309	ChEMBL
SI	43.0 beats min-1	PMID1350309	ChEMBL

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