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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Thromboxane A2 receptor
Species	Rattus norvegicus (Rat)
Gene	Tbxa2r
Synonym	prostanoid TP receptor TP receptor TXA2-R TXR2
Disease	N/A for non-human GPCRs
Length	341
Amino acid sequence	MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
UniProt	P34978
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3156
IUPHAR	346
DrugBank	N/A

Ligand

Name	CHEMBL296727
Molecular formula	C25H25ClN3NaO3
IUPAC name	sodium;3-[(4E)-4-[(4-chlorophenyl)carbamoylhydrazinylidene]butyl]-6-propan-2-ylazulene-1-carboxylate
Molecular weight	473.933
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	None
Synonyms	N/A
Inchi Key	KCUSJMHAPDMEOT-RRIBZKRYSA-M
Inchi ID	InChI=1S/C25H26ClN3O3.Na/c1-16(2)17-6-12-21-18(15-23(24(30)31)22(21)13-7-17)5-3-4-14-27-29-25(32)28-20-10-8-19(26)9-11-20;/h6-16H,3-5H2,1-2H3,(H,30,31)(H2,28,29,32);/q;+1/p-1/b27-14+;
PubChem CID	44291910
ChEMBL	CHEMBL296727
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<100000.0 nM	Bioorg. Med. Chem. Lett., (1993) 3:8:1687	ChEMBL

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