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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Cavia porcellus (Guinea pig)
Gene	Adrb2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	418
Amino acid sequence	MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
UniProt	Q8K4Z4
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5414
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3277367
Molecular formula	C12H17N3O
IUPAC name	1-(3H-benzimidazol-5-yl)-2-(propan-2-ylamino)ethanol
Molecular weight	219.288
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	1.0
Synonyms	SCHEMBL11476231
Inchi Key	AYYAZGVQQWKVRG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H17N3O/c1-8(2)13-6-12(16)9-3-4-10-11(5-9)15-7-14-10/h3-5,7-8,12-13,16H,6H2,1-2H3,(H,14,15)
PubChem CID	20340041
ChEMBL	CHEMBL3277367
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
%max	58.0 %	PMID619150	ChEMBL
Activity	4.79 %	PMID619150	ChEMBL
ED50	1.6 uM	PMID619150	ChEMBL
FC	2.0 -	PMID619150	ChEMBL
pD2	5.78 -	PMID619150	ChEMBL

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