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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Glucagon receptor
Species	Mus musculus (Mouse)
Gene	Gcgr
Synonym	GGR GL-R glucagon receptor GR
Disease	N/A for non-human GPCRs
Length	485
Amino acid sequence	MPLTQLHCPHLLLLLLVLSCLPEAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQPWRNASQCQLDDEEIEVQKGVAKMYSSQQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAMAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSLATFSERSFFSLYLGIGWGAPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVFLALLINFFIFVHIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSTKLFFDLFLSSFQGLLVAVLYCFLNKEVQAELMRRWRQWQEGKALQEERLASSHGSHMAPAGPCHGDPCEKLQLMSAGSSSGTGCVPSMETSLASSLPRLADSPT
UniProt	Q61606
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4773
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL348401
Molecular formula	C21H21FN2
IUPAC name	4-[5-cyclohexyl-3-(4-fluorophenyl)-1H-pyrrol-2-yl]pyridine
Molecular weight	320.411
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50075769 4-[5-Cyclohexyl-3-(4-fluoro-phenyl)-1H-pyrrol-2-yl]-pyridine
Inchi Key	KVOWJSITTRQRSW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H21FN2/c22-18-8-6-15(7-9-18)19-14-20(16-4-2-1-3-5-16)24-21(19)17-10-12-23-13-11-17/h6-14,16,24H,1-5H2
PubChem CID	44372406
ChEMBL	CHEMBL348401
IUPHAR	N/A
BindingDB	50075769
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<1000.0 nM	PMID10201821	BindingDB,ChEMBL

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