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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	Somatostatin receptor type 5
Species	Homo sapiens (Human)
Gene	SSTR5
Synonym	SOMATO SS-5-R SS5-R SS5R SST5 receptor
Disease	N/A
Length	364
Amino acid sequence	MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQTSKL
UniProt	P35346
Protein Data Bank	N/A
GPCR-HGmod model	P35346
3D structure model	This predicted structure model is from GPCR-EXP P35346.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1792
IUPHAR	359
DrugBank	BE0002147

Ligand

Name	CHEMBL238057
Molecular formula	C22H27N3O2S
IUPAC name	N-[1-[(3-ethoxy-4-methoxyphenyl)methyl]piperidin-4-yl]-1,3-benzothiazol-2-amine
Molecular weight	397.537
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.1
Synonyms	BDBM50227103 N-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-yl)benzo[d]thiazol-2-amine SCHEMBL3579402
Inchi Key	AZFULYRYQKRUCE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27N3O2S/c1-3-27-20-14-16(8-9-19(20)26-2)15-25-12-10-17(11-13-25)23-22-24-18-6-4-5-7-21(18)28-22/h4-9,14,17H,3,10-13,15H2,1-2H3,(H,23,24)
PubChem CID	24740748
ChEMBL	CHEMBL238057
IUPHAR	N/A
BindingDB	50227103
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	326.0 nM	PMID18020390	BindingDB,ChEMBL

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