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Name | G-protein coupled receptor 55 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR55 |
Synonym | GPR55 |
Disease | N/A |
Length | 319 |
Amino acid sequence | MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG |
UniProt | Q9Y2T6 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q9Y2T6 |
3D structure model | This predicted structure model is from GPCR-EXP Q9Y2T6. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1075322 |
IUPHAR | 109 |
DrugBank | BE0005802 |
Name | CHEMBL3220946 |
---|---|
Molecular formula | C20H18N2O3S |
IUPAC name | ethyl 6-oxo-5,5-diphenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazole-2-carboxylate |
Molecular weight | 366.435 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 0 |
XlogP | 3.6 |
Synonyms | 5,5-Diphenyl-6-oxo-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole-2-carboxylic acid ethyl ester |
Inchi Key | LLWVWQYDADULBL-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C20H18N2O3S/c1-2-25-17(23)16-13-22-19(26-16)21-18(24)20(22,14-9-5-3-6-10-14)15-11-7-4-8-12-15/h3-12,16H,2,13H2,1H3 |
PubChem CID | 21858022 |
ChEMBL | CHEMBL3220946 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 58.0 % | MedChemComm, (2014) 5:5:632 | ChEMBL |
IC50 | <10000.0 nM | MedChemComm, (2014) 5:5:632 | ChEMBL |
Inhibition | 41.0 % | MedChemComm, (2014) 5:5:632 | ChEMBL |
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