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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Glucagon receptor
Species	Mus musculus (Mouse)
Gene	Gcgr
Synonym	GGR GL-R glucagon receptor GR
Disease	N/A for non-human GPCRs
Length	485
Amino acid sequence	MPLTQLHCPHLLLLLLVLSCLPEAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQPWRNASQCQLDDEEIEVQKGVAKMYSSQQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAMAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSLATFSERSFFSLYLGIGWGAPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVFLALLINFFIFVHIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSTKLFFDLFLSSFQGLLVAVLYCFLNKEVQAELMRRWRQWQEGKALQEERLASSHGSHMAPAGPCHGDPCEKLQLMSAGSSSGTGCVPSMETSLASSLPRLADSPT
UniProt	Q61606
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4773
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL346698
Molecular formula	C23H19ClN2O
IUPAC name	4-[5-(4-chlorophenyl)-3-(2-ethoxyphenyl)-1H-pyrrol-2-yl]pyridine
Molecular weight	374.868
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.6
Synonyms	2-(4-Pyridinyl)-3-(2-ethoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrole BDBM50075754 4-[5-(4-Chloro-phenyl)-3-(2-ethoxy-phenyl)-1H-pyrrol-2-yl]-pyridine
Inchi Key	MDNFXHVVRABLPD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H19ClN2O/c1-2-27-22-6-4-3-5-19(22)20-15-21(16-7-9-18(24)10-8-16)26-23(20)17-11-13-25-14-12-17/h3-15,26H,2H2,1H3
PubChem CID	44372676
ChEMBL	CHEMBL346698
IUPHAR	N/A
BindingDB	50075754
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	340.0 nM	PMID10201821	BindingDB,ChEMBL
Inhibition	22.0 %	PMID10201821	ChEMBL

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