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Name | Beta-2 adrenergic receptor |
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Species | Cavia porcellus (Guinea pig) |
Gene | Adrb2 |
Synonym | Beta-2 adrenoceptor Beta-2 adrenoreceptor |
Disease | N/A for non-human GPCRs |
Length | 418 |
Amino acid sequence | MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL |
UniProt | Q8K4Z4 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5414 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL105434 |
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Molecular formula | C13H19NO3 |
IUPAC name | 1-[(propan-2-ylamino)methyl]-3,4-dihydro-1H-isochromene-5,6-diol |
Molecular weight | 237.299 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 3 |
XlogP | 1.3 |
Synonyms | 1-(Isopropylamino-methyl)-isochroman-5,6-diol BDBM50041913 1-[(Isopropylamino)methyl]-3,4-dihydro-1H-2-benzopyran-5,6-diol |
Inchi Key | MQBIFSRHBOTBBZ-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C13H19NO3/c1-8(2)14-7-12-9-3-4-11(15)13(16)10(9)5-6-17-12/h3-4,8,12,14-16H,5-7H2,1-2H3 |
PubChem CID | 12828570 |
ChEMBL | CHEMBL105434 |
IUPHAR | N/A |
BindingDB | 50041913 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
pD2 | >3.5 - | PMID8230093 | ChEMBL |
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