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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	G-protein coupled receptor 55
Species	Homo sapiens (Human)
Gene	GPR55
Synonym	GPR55
Disease	N/A
Length	319
Amino acid sequence	MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATSIYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRFLAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAKVFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFLPVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIRAHRPSRVQLVLQDTTISRG
UniProt	Q9Y2T6
Protein Data Bank	N/A
GPCR-HGmod model	Q9Y2T6
3D structure model	This predicted structure model is from GPCR-EXP Q9Y2T6.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075322
IUPHAR	109
DrugBank	BE0005802

Ligand

Name	CHEMBL3221182
Molecular formula	C15H16N2O3S
IUPAC name	(2Z)-2-[(2,3-dimethoxyphenyl)methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-one
Molecular weight	304.364
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.5
Synonyms	N/A
Inchi Key	BEJABIGGCSYDJF-LUAWRHEFSA-N
Inchi ID	InChI=1S/C15H16N2O3S/c1-19-12-6-3-5-10(13(12)20-2)9-11-14(18)17-7-4-8-21-15(17)16-11/h3,5-6,9H,4,7-8H2,1-2H3/b11-9-
PubChem CID	90667653
ChEMBL	CHEMBL3221182
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Activity	0.0 %	MedChemComm, (2014) 5:5:632	ChEMBL
IC50	16400.0 nM	MedChemComm, (2014) 5:5:632	ChEMBL

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