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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Prostaglandin D2 receptor
Species	Mus musculus (Mouse)
Gene	Ptgdr
Synonym	prostanoid DP receptor-like Prostanoid DP receptor prostaglandin D2 receptor (DP) PGD2 receptor PGD receptor DP1 receptor DP1 PTGDR1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	357
Amino acid sequence	MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
UniProt	P70263
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3933
IUPHAR	338
DrugBank	N/A

Ligand

Name	CHEMBL184684
Molecular formula	C26H21NO6
IUPAC name	2-[1-[4-(1,3-benzodioxol-2-ylmethoxy)benzoyl]-2-methylindol-4-yl]acetic acid
Molecular weight	443.455
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.9
Synonyms	{1-[4-(Benzo[1,3]dioxol-2-ylmethoxy)-benzoyl]-2-methyl-1H-indol-4-yl}-acetic acid BDBM50152516 SCHEMBL5851218
Inchi Key	NGFCHDLVALKPTJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H21NO6/c1-16-13-20-18(14-24(28)29)5-4-6-21(20)27(16)26(30)17-9-11-19(12-10-17)31-15-25-32-22-7-2-3-8-23(22)33-25/h2-13,25H,14-15H2,1H3,(H,28,29)
PubChem CID	21974328
ChEMBL	CHEMBL184684
IUPHAR	N/A
BindingDB	50152516
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	9.4 nM	PMID15341946	BindingDB,ChEMBL

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