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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A3
Species	Bos taurus (Bovine)
Gene	ADORA3
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	317
Amino acid sequence	MPVNSTAVSLASVTYISVEILIGLCAIVGNVLVIWVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVISLGVTIHFYSCLLMTCLLMIFTHASIMSLLAIAVDRYLRVKLTVRYRRVTTQRRIWLALGLCWLVSFLVGLTPMFGWNMKLSSADKNLTFLPCQFRSVMRMDYMVYFSFFTWILIPLVVMCAIYFDIFYVIRNRLSQNFSGSKETGAFYGREFKTAKSLSLVLFLFALSWLPLSIINCIIYFNGEVPQIVLYLGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVICQPSKSMDPSIEQTSE
UniProt	Q0VC81
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1287626
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL112756
Molecular formula	C21H14N4O
IUPAC name	3,10-diphenyl-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Molecular weight	338.37
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.9
Synonyms	3,10-Diphenyl[1,2,4]triazino[4,3-a]benzimidazole-4(10H)-one 3,10-Diphenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one BDBM50102282
Inchi Key	BFVHCJSDSWWYEY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H14N4O/c26-20-19(15-9-3-1-4-10-15)22-23-21-24(16-11-5-2-6-12-16)17-13-7-8-14-18(17)25(20)21/h1-14H
PubChem CID	10449783
ChEMBL	CHEMBL112756
IUPHAR	N/A
BindingDB	50102282
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<1000.0 nM	PMID20937560	BindingDB,ChEMBL

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