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GPCR

NameP2Y purinoceptor 2
SpeciesMus musculus (Mouse)
GeneP2ry2
SynonymPurinergic receptor
P2Y2 receptor
P2Y2
P2Y purinoceptor 2
ATP receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length373
Amino acid sequenceMAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSETKDIRL
UniProtP35383
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1075298
IUPHARN/A
DrugBankN/A

Ligand

NameCHEMBL404659
Molecular formulaC20H12N3O7S-
IUPAC name1-amino-4-(3-nitroanilino)-9,10-dioxoanthracene-2-sulfonate
Molecular weight438.39
Hydrogen bond acceptor9
Hydrogen bond donor2
XlogP3.3
SynonymsBDBM50227018
sodium 1-amino-4-(3-nitrophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
Inchi KeyBFYKRGJJESUQPP-UHFFFAOYSA-M
Inchi IDInChI=1S/C20H13N3O7S/c21-18-15(31(28,29)30)9-14(22-10-4-3-5-11(8-10)23(26)27)16-17(18)20(25)13-7-2-1-6-12(13)19(16)24/h1-9,22H,21H2,(H,28,29,30)/p-1
PubChem CID91935665
ChEMBLN/A
IUPHARN/A
BindingDB50227018
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
IC50<100000.0 nMPMID18006312BindingDB

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