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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Thromboxane A2 receptor
Species	Mus musculus (Mouse)
Gene	Tbxa2r
Synonym	Prostanoid TP receptor TP receptor TXA2-R
Disease	N/A for non-human GPCRs
Length	341
Amino acid sequence	MWPNGTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAIVASQHAALLDWRATDPSCRLCYFMGVAMVFFGLCPLLLGAAMASERFVGITRPFSRPTATSRRAWATVGLVWVAAGALGLLPLLGLGRYSVQYPGSWCFLTLGTQRGDVVFGLIFALLGSASVGLSLLLNTVSVATLCRVYHTREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFIMQTLLQTPPVMSFSGQLLRATEHQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFSSQLQAVSLRRPPAQAMLSGP
UniProt	P30987
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1795181
IUPHAR	346
DrugBank	N/A

Ligand

Name	CHEMBL2315057
Molecular formula	C27H21Cl2FN2O4S
IUPAC name	6-[[5-chloro-2-[(4-chloro-2-fluorophenyl)methoxy]phenyl]methyl]-N-(4-methylphenyl)sulfonylpyridine-2-carboxamide
Molecular weight	559.433
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	6.7
Synonyms	BDBM50424382
Inchi Key	NVPDIBBYSPFSSM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H21Cl2FN2O4S/c1-17-5-10-23(11-6-17)37(34,35)32-27(33)25-4-2-3-22(31-25)14-19-13-20(28)9-12-26(19)36-16-18-7-8-21(29)15-24(18)30/h2-13,15H,14,16H2,1H3,(H,32,33)
PubChem CID	71517031
ChEMBL	CHEMBL2315057
IUPHAR	N/A
BindingDB	50424382
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<1000.0 nM	PMID23218714	ChEMBL

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