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GPCR

NameP2Y purinoceptor 6
SpeciesRattus norvegicus (Rat)
GeneP2ry6
SynonymP2Y ATP receptor 6
P2Y purinoceptor 6
P2Y6
P2Y6 receptor
pyrimidinergic receptor P2Y
[ Show all ]
DiseaseN/A for non-human GPCRs
Length328
Amino acid sequenceMERDNGTIQAPGLPPTTCVYREDFKRLLLPPVYSVVLVVGLPLNVCVIAQICASRRTLTRSAVYTLNLALADLLYACSLPLLIYNYARGDHWPFGDLACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWVVCGVVWLVVTAQCLPTAVFAATGIQRNRTVCYDLSPPILSTRYLPYGMALTVIGFLLPFTALLACYCRMARRLCRQDGPAGPVAQERRSKAARMAVVVAAVFVISFLPFHITKTAYLAVRSTPGVSCPVLETFAAAYKGTRPFASANSVLDPILFYFTQQKFRRQPHDLLQKLTAKWQRQRV
UniProtQ63371
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3543
IUPHAR326
DrugBankN/A

Ligand

NameCHEMBL590956
Molecular formulaC21H12FN2O7S-
IUPAC name1-amino-4-(2-carboxy-4-fluoroanilino)-9,10-dioxoanthracene-2-sulfonate
Molecular weight455.392
Hydrogen bond acceptor10
Hydrogen bond donor3
XlogP3.1
SynonymsSodium 1-amino-4-[4-fluoro-2-carboxyphenylamino]-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
BDBM50307835
Inchi KeyOBFSYBSKXOCXQH-UHFFFAOYSA-M
Inchi IDInChI=1S/C21H13FN2O7S/c22-9-5-6-13(12(7-9)21(27)28)24-14-8-15(32(29,30)31)18(23)17-16(14)19(25)10-3-1-2-4-11(10)20(17)26/h1-8,24H,23H2,(H,27,28)(H,29,30,31)/p-1
PubChem CID91934095
ChEMBLN/A
IUPHARN/A
BindingDB50307835
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Experimental Data

ParameterValueReferenceDatabase source
IC5010000.0 nMPMID20146483BindingDB

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