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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Thromboxane A2 receptor
Species	Rattus norvegicus (Rat)
Gene	Tbxa2r
Synonym	prostanoid TP receptor TP receptor TXA2-R TXR2
Disease	N/A for non-human GPCRs
Length	341
Amino acid sequence	MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
UniProt	P34978
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3156
IUPHAR	346
DrugBank	N/A

Ligand

Name	CHEMBL43772
Molecular formula	C24H20ClFN2O4S
IUPAC name	3-[5-[(4-chlorophenyl)sulfonylamino]-3-[(4-fluorophenyl)methyl]indol-1-yl]propanoic acid
Molecular weight	486.942
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.6
Synonyms	BDBM50403568 SCHEMBL8537998
Inchi Key	BJRFXMWKJZXEBT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H20ClFN2O4S/c25-18-3-8-21(9-4-18)33(31,32)27-20-7-10-23-22(14-20)17(15-28(23)12-11-24(29)30)13-16-1-5-19(26)6-2-16/h1-10,14-15,27H,11-13H2,(H,29,30)
PubChem CID	18926534
ChEMBL	CHEMBL43772
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Kd	0.2344 nM	Bioorg. Med. Chem. Lett., (1996) 6:14:1691	ChEMBL

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