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Name | Free fatty acid receptor 1 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Ffar1 |
Synonym | FFA1 receptor FFA1R G protein-coupled receptor 40 G-protein coupled receptor 40 GPR40 |
Disease | N/A for non-human GPCRs |
Length | 300 |
Amino acid sequence | MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLRLTPSLVYTLHLGCSDLLLAITLPLKAVEALASGAWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPRYSWGVCVAIWALVLCHLGLALGLETSGSWLDNSTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVRSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLGGSWRKLGLITGAWSVVLNPLVTGYLGTGPGRGTICVTRTQRGTIQK |
UniProt | Q76JU9 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5411 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL229227 |
---|---|
Molecular formula | C17H20O3S |
IUPAC name | 3-(4-butoxyphenyl)-3-thiophen-2-ylpropanoic acid |
Molecular weight | 304.404 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 1 |
XlogP | 4.1 |
Synonyms | SCHEMBL2944117 3-(4-butoxyphenyl)-3-(thiophen-2-yl)propanoic acid 3-Aryl-3-(4-phenoxy)-propionic Acid derivative, 46 BDBM22492 |
Inchi Key | PNGSWCVAXCXVHE-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C17H20O3S/c1-2-3-10-20-14-8-6-13(7-9-14)15(12-17(18)19)16-5-4-11-21-16/h4-9,11,15H,2-3,10,12H2,1H3,(H,18,19) |
PubChem CID | 16737695 |
ChEMBL | CHEMBL229227 |
IUPHAR | N/A |
BindingDB | 22492 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Activity | 171.0 % | PMID17500511 | ChEMBL |
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