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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1B angiotensin II receptor
Species	Rattus norvegicus (Rat)
Gene	Agtr1b
Synonym	Angiotensin II type-1B receptor AT1B AT3
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
UniProt	P29089
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL263
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL131209
Molecular formula	C32H36N4O3
IUPAC name	2-[4-[[2-butyl-7-(cyclohexylcarbamoylamino)benzimidazol-1-yl]methyl]phenyl]benzoic acid
Molecular weight	524.665
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	6.7
Synonyms	4''-[2-Butyl-7-(3-cyclohexyl-ureido)-benzoimidazol-1-ylmethyl]-biphenyl-2-carboxylic acid BDBM50043276 SCHEMBL8393841 4'-[[2-Butyl-7-(3-cyclohexylureido)-1H-benzimidazol-1-yl]methyl]-1,1'-biphenyl-2-carboxylic acid
Inchi Key	BLKXPTJWHWQXCM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H36N4O3/c1-2-3-16-29-34-27-14-9-15-28(35-32(39)33-24-10-5-4-6-11-24)30(27)36(29)21-22-17-19-23(20-18-22)25-12-7-8-13-26(25)31(37)38/h7-9,12-15,17-20,24H,2-6,10-11,16,21H2,1H3,(H,37,38)(H2,33,35,39)
PubChem CID	9984310
ChEMBL	CHEMBL131209
IUPHAR	N/A
BindingDB	50043276
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	160.0 nM	PMID8258826	BindingDB,ChEMBL

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