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GPCR

NameLysophosphatidic acid receptor 2
SpeciesHomo sapiens (Human)
GeneLPAR2
Synonymendothelial differentiation gene 4, lysophosphatidic acid G-protein-coupled receptor 4
LPA receptor 2
LPA-2
Edg4
Lysophosphatidic acid receptor Edg-4
[ Show all ]
DiseaseN/A
Length351
Amino acid sequenceMVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
UniProtQ9HBW0
Protein Data BankN/A
GPCR-HGmod modelQ9HBW0
3D structure modelThis predicted structure model is from GPCR-EXP Q9HBW0.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3724
IUPHAR273
DrugBankN/A

Ligand

NameCHEMBL381470
Molecular formulaC16H32KO6P
IUPAC namepotassium;(2-dodecyl-1,3-dioxolan-4-yl)methyl hydrogen phosphate
Molecular weight390.498
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogPNone
SynonymsN/A
Inchi KeyPUIPOGMHHGKFAG-UHFFFAOYSA-M
Inchi IDInChI=1S/C16H33O6P.K/c1-2-3-4-5-6-7-8-9-10-11-12-16-20-13-15(22-16)14-21-23(17,18)19;/h15-16H,2-14H2,1H3,(H2,17,18,19);/q;+1/p-1
PubChem CID44406630
ChEMBLCHEMBL381470
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessPartition coefficient log P of this ligand is not available.

Experimental Data

ParameterValueReferenceDatabase source
IC507430.0 nMPMID16290140ChEMBL
Ki745.0 nMPMID16290140ChEMBL

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