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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Platelet-activating factor receptor
Species	Cavia porcellus (Guinea pig)
Gene	PTAFR
Synonym	PAF-R PAFr
Disease	N/A for non-human GPCRs
Length	342
Amino acid sequence	MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
UniProt	P21556
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5136
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL273638
Molecular formula	C42H65ClN4O6
IUPAC name	[(2R,4R)-1-benzoyl-4-(octadecylcarbamoyloxymethyl)azetidin-2-yl]methyl N-acetyl-N-[(1-ethylpyridin-1-ium-2-yl)methyl]carbamate;chloride
Molecular weight	757.454
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	None
Synonyms	N/A
Inchi Key	BNBMJJSMZNFFEX-RUKDTIIFSA-N
Inchi ID	InChI=1S/C42H64N4O6.ClH/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-43-41(49)51-33-38-31-39(46(38)40(48)36-26-21-20-22-27-36)34-52-42(50)45(35(3)47)32-37-28-23-25-30-44(37)5-2;/h20-23,25-28,30,38-39H,4-19,24,29,31-34H2,1-3H3;1H/t38-,39-;/m1./s1
PubChem CID	44268191
ChEMBL	CHEMBL273638
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
IC50	138.0 nM	Bioorg. Med. Chem. Lett., (1995) 5:10:1097	ChEMBL
Ki	104.0 nM	Bioorg. Med. Chem. Lett., (1995) 5:10:1097	ChEMBL

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